Funding: Approximately $3.8M is expected to fund four awards, with a total cost cap of $950,000 per award.
Doc Type: BAA
Clearance:No
Program Manager: help@eBRAP.org
Last Updated: 2026-08-19 14:45
Analyzed File:HT942526ORPARA_GG.pdf
Eligibility Reasoning
Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities. ... Applications involving interdisciplinary collaborations among academia, industry, the military services, the U.S. Department of Veterans Affairs (VA) and/or other federal agencies are highly encouraged.
Note: This is an AI-generated summary...
Summary
The Department of War's (DOW) Orthopaedic Research Program (ORP) is offering the Applied Research Award (ARA) to fund applied research focused on advancing optimal treatment and restoring function for individuals with orthopaedic injuries from combat or service-related activities. Proposals must address one or more of five specific focus areas: Battlefield Fracture-Related Infection, Composite Tissue Regeneration, Limb Stabilization and Protection, Osteointegration Outcomes, or Return-to-Duty Strategies. This grant requires preliminary data and a strong emphasis on military relevance. The program defines applied research as work that refines concepts into potential solutions and evaluates the technical feasibility of new products, interventions, or technologies. Clinical trials and fundamental basic research are not allowed. The program expects to fund approximately four awards, with a total cost cap of $950,000 per award for a maximum performance period of three years.
Battlefield Fracture-Related Infection: Strategies to decrease the burden of fracture-related infections on the battlefield, which may include prevention, early detection or improved eradication. The ORP encourages applications proposing alternatives to systemic antibiotic delivery. The ORP will not consider applications proposing strategies not feasible in a battlefield or combat environment.
Composite Tissue Regeneration: Advanced tissue regeneration therapeutics in composite tissue for the restoration of traumatically injured extremities. The ORP encourages applications proposing techniques aimed at improving outcomes following high-energy extremity trauma, with a focus on improving wound healing and neuromuscular recovery following composite tissue loss and segmental bone loss. The ORP will not consider tissue engineering studies that solely address bone, cartilage, muscle or nerve.
Limb Stabilization and Protection: Development and/or clinical evaluation of rapid limb stabilization and novel wound protectants for severely or critically wounded limbs to enable prolonged care and eventual transport to the point of definitive treatment. The ORP will not consider applications proposing interventions that solely address infection.
Osteointegration Outcomes: Identification of best practices to optimize outcomes of patients who have percutaneous osseointegrated prosthetic limbs, e.g., infection, rejection, adapters and fail-safe devices, clinical outcomes.
Return-to-Duty Strategies: Optimization and/or validation of decision-support tools, interventions and/or rehabilitation strategies that can retain a Service Member on duty, enable them to return to duty within one year of injury or avoid reinjury for common combat-related musculoskeletal injuries. Applications must describe the current standard of care and the proposed rehabilitation strategy, as applicable. The ORP encourages applications proposing treatment strategies for use along the continuum of care, capabilities for diagnosis of underlying pathology and efficacy of intervention measurements. The ORP will not consider applications proposing biomarker studies.
Specific Technical Skills:
Battlefield Fracture-Related Infection: Strategies to decrease the burden of fracture-related infections on the battlefield, which may include prevention, early detection or improved eradication. The ORP encourages applications proposing alternatives to systemic antibiotic delivery. The ORP will not consider applications proposing strategies not feasible in a battlefield or combat environment.Composite Tissue Regeneration: Advanced tissue regeneration therapeutics in composite tissue for the restoration of traumatically injured extremities. The ORP encourages applications proposing techniques aimed at improving outcomes following high-energy extremity trauma, with a focus on improving wound healing and neuromuscular recovery following composite tissue loss and segmental bone loss. The ORP will not consider tissue engineering studies that solely address bone, cartilage, muscle or nerve.Limb Stabilization and Protection: Development and/or clinical evaluation of rapid limb stabilization and novel wound protectants for severely or critically wounded limbs to enable prolonged care and eventual transport to the point of definitive treatment. The ORP will not consider applications proposing interventions that solely address infection.Osteointegration Outcomes: Identification of best practices to optimize outcomes of patients who have percutaneous osseointegrated prosthetic limbs, e.g., infection, rejection, adapters and fail-safe devices, clinical outcomes.Return-to-Duty Strategies: Optimization and/or validation of decision-support tools, interventions and/or rehabilitation strategies that can retain a Service Member on duty, enable them to return to duty within one year of injury or avoid reinjury for common combat-related musculoskeletal injuries. Applications must describe the current standard of care and the proposed rehabilitation strategy, as applicable. The ORP encourages applications proposing treatment strategies for use along the continuum of care, capabilities for diagnosis of underlying pathology and efficacy of intervention measurements. The ORP will not consider applications proposing biomarker studies.
Potential PIs for this Area:
Name
Score
Organization
Potential LBNL PIs (Overall)
Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.
BSA | Biological Systems & Engineering | Process Engr & Analytics · Battlefield Fracture-Related Infection
Fundamental Research Exemption (FRE)
Awards may not be used to support fundamental basic research. Basic research is defined as research directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications toward process or products in mind.
ONHS Funding Opportunity Report