Funding: Approximately $9.0M is allotted to fund about six applications. Individual awards have total cost caps of $1.0M for Research Level 1 and $2.0M for Research Level 2.
Doc Type: BAA
Clearance:No
Program Manager: N/A
Last Updated: 2026-08-19 14:50
Analyzed File:HT942526TBIPHRPTRA-GG.pdf
Eligibility Reasoning
Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities. ... Applications from investigators within the DOW and applications involving multidisciplinary collaborations among academia, industry, the DOW, the U.S. Department of Veterans Affairs (VA) and other federal government agencies are highly encouraged.
Note: This is an AI-generated summary...
Summary
The FY26 Traumatic Brain Injury and Psychological Health (TBIPHRP) Translational Research Award (TRA) is a grant from the Defense Health Agency designed to accelerate the conversion of scientific findings into impactful clinical applications for TBI and psychological health. The award prioritizes innovative, non-incremental research and explicitly prohibits basic research and clinical trials. Proposals must address one of three focus areas: 1) Understand, 2) Prevent and Assess, or 3) Treat. The award is structured into two funding tiers: Research Level 1, with a $1.0M cost cap, supports the refinement of mature concepts into products for further evaluation, and Research Level 2, with a $2.0M cost cap, supports rigorous evaluation of products in preparation for first-in-human studies. Preliminary data is required. For research prospectively enrolling human subjects, a community-based participatory research (CBPR) approach is mandatory. The program also offers an Early-Career Investigator Partnering Option, allowing for a collaboration between an established and an early-career PI, with separate awards for each.
Overall Technical Areas
Traumatic Brain Injury (TBI) EtiologyPsychological Health EtiologyBiological Risk Factor AnalysisBiomarker Identification and ValidationObjective Diagnostic MethodsReal-time Health MonitoringClinical Data ModelingTBI Prevention TechnologiesNeuroprotective InterventionsPsychological Resilience InterventionsSuicide and Violence PreventionFunctional Recovery InterventionsNeurorehabilitation TherapiesPersonalized Medicine ApproachesMobile Health (mHealth) Technologies
Probable LBNL Areas
N/A
Focus Areas
Example Priorities:
Understanding of risk, protective and biological factors, including sex as a biological variable, contributing to an individual’s vulnerability to, response to and long-term outcomes of psychological health conditions and/or TBI.
Understanding psychological health factors or outcomes associated with sexual harassment and assault perpetration, victimization and barriers to reporting and response.
Development and analysis of modeling from clinical data and other human data (e.g., electronic health records, exposure, training and/or occupational data) to forecast the long-term and/or late effects of brain exposures, such as TBI, and co-occurring conditions.
Specific Technical Skills:
EpidemiologyEtiologyNeurobiologyPathophysiologyBiostatisticsClinical Data ModelingGeneticsSocial Science ResearchPsychologySABV Analysis
Potential PIs for this Area:
Name
Score
Organization
Example Priorities:
Identification and validation of biomarkers or other objective methods for assessment, diagnosis, prognosis or real-time monitoring of psychological health conditions and/or TBI, including subclinical presentations, and associated sequelae of these conditions.
Development and evaluation of approaches or tools to prevent or reduce risk of psychological health conditions and/or TBI.
Development and evaluation of crosscutting prevention approaches to address multiple adverse outcomes such as suicide, interpersonal violence including intimate partner and family violence, sexual assault, psychological health issues and/or TBI.
Development and evaluation of solutions to support military and Family readiness and increase psychological resilience in individuals to the potential negative impacts of specific military and life stressors.
Specific Technical Skills:
Biomarker DiscoveryDiagnostic Assay DevelopmentPrognostic ModelingReal-time Health MonitoringSensor Data AnalysisPreventive MedicineProtective Materials SciencePsychometricsClinical Decision SupportResilience Training
Potential PIs for this Area:
Name
Score
Organization
Example Priorities:
Interventions that promote sustained functional recovery, including interventions administered acutely, during the post-acute phase or chronic phase of injury.
Development of postvention strategies to support individuals in workplace or community environments following a sexual assault, suicide event or other trauma.
Health services research to improve the adoption of evidence-based practices, access to care, or reduce barriers to care.
Personalized medicine approaches to treatment that may include tailoring treatment to the biological and endophenotypic elements present.
In accordance with National Security Presidential Memorandum-33 and all associated laws, all fundamental research funded by the DOW must be evaluated for affiliations with foreign entities.
ONHS Funding Opportunity Report