ONHS Report: HT942526TERPIIRA

DoW Toxic Exposures Investigator Initiated Research Award

Solicitation ID: HT942526TERPIIRA

Agency: DHA

Type: Grant

Deadline: 2026-11-19T00:00:00 ET

Eligibility: Yes (Unrestricted)

Funding: Approximately $2.4M is expected to fund three awards, with a total cost cap of $800,000 per award.

Doc Type: BAA

Clearance: No

Program Manager: help@eBRAP.org

Last Updated: 2026-08-19 14:48

Analyzed File: HT942526TERPIIRA_GG.pdf

Eligibility Reasoning

Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities. ... Intragovernmental obligations of funding will be made according to the terms of a negotiated Inter-Agency Agreement and managed by a CDMRP Science Officer.

Note: This is an AI-generated summary...

Summary

The Fiscal Year 2026 (FY26) Toxic Exposures Research Program (TERP) Investigator-Initiated Research Award (IIRA) supports studies contributing to research and patient care for diseases associated with military-related toxic exposures. This award is open to independent investigators at all career levels. The scope of research can range from basic laboratory to translational research, including preclinical studies, human subject research, correlative studies, and New Approach Methodologies. Clinical trials are explicitly excluded. Applicants must provide preliminary data and address at least one of the FY26 TERP program goals (Predict and Prevent; Diagnose; Treat) and one topic area (Neurotoxin Exposure; Gulf War Illness and Its Treatment; Airborne Hazards and Burn Pits; or Other Military Service-Related Toxic Exposures). The award provides a maximum of $800,000 in total costs for a performance period of up to 3 years. Approximately three awards are expected to be funded.

Overall Technical Areas

Toxic Exposure Health EffectsReproductive ToxicologyMultigenerational Health EffectsNeurotoxicology ResearchEnvironmental Exposure MonitoringExposure Biomarker DiscoveryDiagnostic Assay DevelopmentTherapeutic DevelopmentPreclinical Model DevelopmentGulf War Illness ResearchAirborne Hazard ResearchEpidemiological ResearchTranslational ResearchBiostatistics and Data Analysis

Probable LBNL Areas

N/A

Focus Areas

Example Priorities:

Identify strategies that can anticipate, identify, monitor and prevent adverse effects of exposures to toxic substances.
Understand the full range of effects from military-related environmental and toxic exposures to aid in predicting/preventing the effects.
Understand the mechanisms of multigenerational effects of military-related toxic exposures and the impact of these exposures on reproductive health to aid in predicting/preventing the effects.
Identify biological and/or psychosocial variables and risk factors that can impact disease outcomes from toxic exposures.
Develop, adapt, validate, or optimize monitoring, for example, personal devices to detect and characterize individual environmental exposures.

Specific Technical Skills:

ToxicologyExposure ScienceEpidemiologyRisk AssessmentSensor DevelopmentPredictive ModelingReproductive HealthGenetic ToxicologyEnvironmental MonitoringPsychosocial Research

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Understand the clinical signs, symptoms, and outcomes associated with exposures, and predict disease progression to develop specific or improved diagnostics.
Understand complex, multi-exposure/physiological or nonchemical stressor (e.g., hormonal, sleep disorders, thermal stress) combinations and how exposure impacts outcome.
Identify biomarkers of exposure to individual or multiple toxic substances alone or in combination with physiological/nonchemical stressors.
Develop diagnostic screens/assays/devices for toxic exposures.

Specific Technical Skills:

Biomarker DiscoveryClinical DiagnosticsAssay DevelopmentMolecular BiologyPathophysiologyImmunologyNeurotoxicologyMulti-omics AnalysisBioinformaticsComputational Biology

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Minimize symptoms and disease progression associated with exposures.
Develop new or improve existing therapeutics, treatments and strategies.
Advance new therapeutics, treatments and strategies.
Address the need for preclinical models that capture the adverse outcomes of human toxic exposures.

Specific Technical Skills:

PharmacologyDrug DiscoveryPreclinical ModelingAnimal ModelsTranslational ResearchNew Approach MethodologiesCellular BiologyGulf War IllnessSymptom ManagementTherapeutic Strategies

Potential PIs for this Area:

Name	Score	Organization

Potential LBNL PIs (Overall)

Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.

Name	Score	Organization
Joshua Apte	0.75	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Environmental Exposure Monitoring
Stephanie Holm	0.74	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Multigenerational Health Effects
Andrew Wyrobek	0.74	LD \| LD \| ONHS · Reproductive Toxicology
Jian-Hua Mao	0.73	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Exposure Biomarker Discovery
Thomas McKone	0.73	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Toxic Exposure Health Effects
Jennifer Rosenbluth	0.72	· Translational Research
Philip Long	0.72	Operations \| Environmental, Health, & Safety \| Occupational Safety · Airborne Hazard Research
Li-Wen (Audrey) Wang	0.72	BSA \| Biological Systems & Engineering \| Biodesign Dept · Diagnostic Assay Development
Zixi Hu	0.72	CSA \| AMCR \| Mathematics · Biostatistics and Data Analysis
Michelle O'Malley	0.71	BSA \| Biological Systems & Engineering \| Biodesign Dept · Therapeutic Development

Fundamental Research Exemption (FRE)

In accordance with National Security Presidential Memorandum-33 and all associated laws, all fundamental research funded by the DOW must be evaluated for affiliations with foreign entities.