ONHS Report: HT942526TERPTRA

DoW Toxic Exposures Translational Research Award

Solicitation ID: HT942526TERPTRA

Agency: DHA

Type: Grant

Deadline: 2026-11-19T00:00:00 ET

Eligibility: Yes (Unrestricted)

Funding: $6.0M total to fund approximately four awards, with a maximum of $1.5M per award.

Doc Type: BAA

Clearance: No

Program Manager: help@eBRAP.org

Last Updated: 2026-08-19 14:52

Analyzed File: HT942526TERPTRA_GG.pdf

Eligibility Reasoning

Extramural and intramural U.S. Department of War (DOW) organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities. ... applications involving multidisciplinary collaborations among academia, industry, the DOW, the VA and other federal government agencies are highly encouraged.

Note: This is an AI-generated summary...

Summary

The Fiscal Year 2026 (FY26) Toxic Exposures Research Program (TERP) Translational Research Award (TRA) supports research to accelerate the translation of promising ideas related to military toxic exposures into clinical applications such as healthcare products, interventions, technologies, or clinical practice guidelines. With an approximate $6.0M allotment, the program expects to fund about four awards, each with a total cost cap of $1.5M for a maximum performance period of three years. A key feature is the Partnering Principal Investigator Option (PPIO) to encourage interdisciplinary collaborations. Proposed projects must address at least one TERP program goal (Predict and Prevent, Diagnose, Treat) and one topic area (e.g., Neurotoxin Exposure, Gulf War Illness, Airborne Hazards). While clinical trials are not allowed, preclinical and clinical research are permitted. Applications must include preliminary data, demonstrate a clear translational pathway, and articulate the project's potential impact on Service Members, Veterans, and their families.

Overall Technical Areas

Translational ScienceMechanistic ToxicologyBiomarker Identification & ValidationDiagnostic Assay DevelopmentTherapeutic DevelopmentPreclinical Model DevelopmentEpidemiological StudiesEnvironmental Exposure MonitoringComplex Exposure AssessmentNeurotoxicology ResearchReproductive & Multigenerational HealthHuman Subjects ResearchStatistical Modeling & Data AnalysisNew Approach Methodologies (NAMs)Correlative Clinical Studies

Probable LBNL Areas

N/A

Focus Areas

Example Priorities:

Identify strategies that can anticipate, identify, monitor, and prevent adverse effects of exposures to toxic substances.
Understand the mechanisms of multigenerational effects of military-related toxic exposures and the impact of these exposures on reproductive health to aid in predicting/preventing the effects.
Identify biological and/or psychosocial variables and risk factors that can impact disease outcomes from toxic exposures.
Develop, adapt, validate, or optimize monitoring, for example, personal devices to detect and characterize individual environmental exposures.

Specific Technical Skills:

EpidemiologyEnvironmental HealthToxicologyGenomicsEpigeneticsReproductive HealthRisk Factor AnalysisSensor DevelopmentExposure MonitoringPsychosocial Research

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Understand the clinical signs, symptoms, and outcomes associated with exposures; and predict disease progression to develop specific or improved diagnostics.
Understand complex, multi-exposure/physiological or nonchemical stressor (e.g., hormonal, sleep disorders, thermal stress) combinations, and how exposure impacts outcome.
Identify biomarkers of exposure to individual or multiple toxic substances alone or in combination with physiological/nonchemical stressors.
Develop diagnostic screens/assays/devices for toxic exposures.

Specific Technical Skills:

Clinical DiagnosticsBiomarker DiscoveryProteomicsMetabolomicsDiagnostic Assay DevelopmentMedical Device DevelopmentClinical PathologySystems BiologyStress PhysiologyData Science

Potential PIs for this Area:

Name	Score	Organization

Example Priorities:

Develop new or improve existing therapeutics, treatments and strategies.
Advance new therapeutics, treatments and strategies.
Address the need for preclinical models that capture the adverse outcomes of human toxic exposures.
Evaluation/treatment of long-term or chronic health impacts of traditional chemical weapons, including but not limited to the long-term effects of sub-lethal doses of sarin, soman, and sulfur mustard and Gulf War illness.

Specific Technical Skills:

Therapeutic DevelopmentPharmacologyPreclinical ModelingAnimal Model DevelopmentTranslational MedicineClinical ResearchToxicologyChronic Disease ManagementImmunotherapyNeurology

Potential PIs for this Area:

Name	Score	Organization

Potential LBNL PIs (Overall)

Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.

Name	Score	Organization
Thomas McKone	0.76	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Complex Exposure Assessment
Joshua Apte	0.75	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Environmental Exposure Monitoring
Zixi Hu	0.75	CSA \| AMCR \| Mathematics · Statistical Modeling & Data Analysis
Stephanie Holm	0.74	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Human Subjects Research
Jian-Hua Mao	0.73	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Biomarker Identification & Validation
Josh North	0.73	EESA \| CESD \| Earth System Sciences · Epidemiological Studies
Marion Russell	0.73	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · New Approach Methodologies (NAMs)
Andrew Wyrobek	0.72	LD \| LD \| ONHS · Reproductive & Multigenerational Health
Jennifer Rosenbluth	0.72	· Translational Science
Li-Wen (Audrey) Wang	0.72	BSA \| Biological Systems & Engineering \| Biodesign Dept · Diagnostic Assay Development

Fundamental Research Exemption (FRE)

In accordance with National Security Presidential Memorandum-33 and all associated laws, all fundamental research funded by the DOW must be evaluated for affiliations with foreign entities.