ONHS Report: HT9427RFI2027LRP

RFI Lupus Research Program (LRP) Public

Solicitation ID: HT9427RFI2027LRP

Agency: Congressionally Directed Medical Research Programs/LRP

Type: Sources Sought

Deadline: 2026-11-16T16:00:00 ET

Eligibility: Yes (Unrestricted)

Funding: N/A

Doc Type: RFI

Clearance: No

Program Manager: jared.d.acre.civ@health.mil

Last Updated: 2026-10-14 16:03

Analyzed File: FY27 LRP RFI survey monkey text_Final.docx

Eligibility Reasoning

The CDMRP wants to hear from all audiences, interested parties, and individuals from academia, industry, community and non-profit organizations, scientific and professional organizations, federal agencies, and the public.

Note: This is an AI-generated summary...

Summary

The Congressionally Directed Medical Research Programs (CDMRP) has released a Request for Information (RFI) on behalf of the Lupus Research Program (LRP) to guide strategic planning and potential future funding opportunities for Fiscal Year 2027 (FY27). This RFI is for information and planning purposes only and does not constitute a solicitation for proposals. The LRP seeks feedback from a wide range of stakeholders, including academia, industry, patient advocates, and the public, through a survey. The survey aims to identify critical gaps in the LRP's current strategic goals and focus areas, determine the most underfunded yet impactful areas of lupus research, and prioritize research types (e.g., heterogeneity, biological mechanisms, quality of life, clinical trials) that would most significantly advance the field.

Overall Technical Areas

Lupus Disease HeterogeneityBiopsychosocial StudiesPersonalized MedicineSystems BiologyEpidemiological StudiesLupus Biological MechanismsPathobiology of End Organ InjuryOutcomes ResearchComparative Effectiveness ResearchMaternal Fetal Health ResearchGenetic and Epigenetic AnalysisGene-Environment InteractionsFunctional Genomic StudiesInnovative Health Care Delivery

Probable LBNL Areas

BSACSAEESAETA

Focus Areas

Example Priorities:

Understanding how lupus disease heterogeneity impacts risk of disease, disease presentation, clinical course and outcomes using a diverse range of research disciplines including, but not limited to, biopsychosocial studies, personalized medicine, variation in treatment studies, health economics, socioeconomic studies, environmental studies, systems biology, maternal fetal health and epidemiological studies.
Understanding the biological mechanisms of lupus disease including, but not limited to, studies of informative/rare patients.
Determining the pathobiology of end organ injury related to lupus disease in target human tissues.
Understanding the underlying genetic and epigenetic components and gene-environment interactions of lupus and how they may relate to clinical disease characteristics, variations, disparities and differences in response to therapies using functional genomic studies.

Specific Technical Skills:

Systems BiologyFunctional GenomicsEpigeneticsImmunologyPathobiologyPersonalized MedicineEpidemiologyEnvironmental StudiesBiopsychosocial StudiesMaternal Fetal Health

Potential PIs for this Area:

Name	Score	Organization
Adam Deutschbauer	0.76	BSA \| Env. Genomics & Sys. Biology \| Comparative and Funct Genomics · Functional Genomics
Sharon Greenblum	0.76	BSA \| DOE Joint Genome Institute \| JGI Technology Dept · Systems Biology
Jamie Inman	0.75	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Systems Biology
Maximilian Auffhammer	0.73	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Environmental Studies
Momoe Kato	0.73	BSA \| Env. Genomics & Sys. Biology \| Comparative and Funct Genomics · Epigenetics
Deepika Awasthi	0.73	BSA \| Biological Systems & Engineering \| Biodesign Dept · Immunology
Cynthia Gerlein-Safdi	0.73	EESA \| CESD \| Integrated Ecosystem Sciences · Maternal Fetal Health
Mohammad Kaazem Pur Mofrad	0.72	BSA \| Molecular Biophysics & Integrated Bioimaging \| Structural Biology Dept · Biopsychosocial Studies
Jian-Hua Mao	0.72	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Personalized Medicine
Joshua Apte	0.72	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Epidemiology

Example Priorities:

Improving quality of life for individuals living with lupus including, but not limited to, addressing social determinants of health, nutrition, alternative therapies, access to health care resources, outcomes research, patient-report outcomes, symptom and disease control, comparative effectiveness research, maternal fetal health and issues and challenges that, when addressed, make day-to-day living with lupus easier and life more fulfilling.
Improving outcomes for lupus through innovative health care delivery models.
Designing and implementing an intervention either at the individual and/or health care system level to improve the quality of life and mental health for individuals living with lupus.

Specific Technical Skills:

Outcomes ResearchHealth Services ResearchComparative Effectiveness ResearchHealth Care Delivery ModelsIntervention DesignPatient-Reported OutcomesSocial Determinants of HealthHealth EconomicsMental Health ResearchNutritional Science

Potential PIs for this Area:

Name	Score	Organization
Stephanie Holm	0.71	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Social Determinants of Health
Timothy Hackmann	0.70	BSA \| DOE Joint Genome Institute \| JGI Science Dept · Nutritional Science
Alan Sanstad	0.70	ETA \| Energy Analysis \| Energy Markets & Planning · Health Economics
Rajshree Deshmukh	0.70	CSA \| SciData \| Data Science Applications · Intervention Design
Drew Paine	0.70	CSA \| SciData \| Data Science Applications · Patient-Reported Outcomes
Dianna LaFerry	0.70	CSA \| Computing \| CSDO Divisional Office · Mental Health Research
Rafael Zamora-Resendiz	0.69	CSA \| AMCR \| Computer Science · Health Services Research
Jing Ke	0.69	ETA \| Energy Analysis \| Energy Efficiency Studies · Comparative Effectiveness Research
Maximilian Auffhammer	0.69	ETA \| Energy Analysis \| Systems & Energy Tech Analysis · Outcomes Research
Eleanor Zizka	0.68	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Health Care Delivery Models

Potential LBNL PIs (Overall)

Note on PI Matching: These suggestions are generated through an AI-driven semantic analysis of LBNL staff profiles.

Name	Score	Organization
Adam Deutschbauer	0.77	BSA \| Env. Genomics & Sys. Biology \| Comparative and Funct Genomics · Functional Genomic Studies
Sharon Greenblum	0.76	BSA \| DOE Joint Genome Institute \| JGI Technology Dept · Systems Biology
Yuko Yoshinaga	0.74	BSA \| DOE Joint Genome Institute \| JGI Technology Dept · Genetic and Epigenetic Analysis
Jian-Hua Mao	0.74	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Personalized Medicine
Mohammad Kaazem Pur Mofrad	0.72	BSA \| Molecular Biophysics & Integrated Bioimaging \| Structural Biology Dept · Biopsychosocial Studies
Kenneth Wan	0.72	ESA \| CSD \| Other Program · Pathobiology of End Organ Injury
Jennifer Rosenbluth	0.72	· Lupus Disease Heterogeneity
Morgan Price	0.72	BSA \| Env. Genomics & Sys. Biology \| Comparative and Funct Genomics · Comparative Effectiveness Research
Abby Dernburg	0.72	BSA \| Biological Systems & Engineering \| Department of BioEngineering and BioMedical Sciences · Lupus Biological Mechanisms
Steven Hofmeyr	0.71	CSA \| AMCR \| Computer Science · Epidemiological Studies

Fundamental Research Exemption (FRE)

Not Mentioned