Coverage Report

Created: 2023-06-07 06:43

/src/htslib/cram/cram_stats.c
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/*
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Copyright (c) 2012-2014, 2016, 2018, 2020 Genome Research Ltd.
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Author: James Bonfield <jkb@sanger.ac.uk>
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Redistribution and use in source and binary forms, with or without
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modification, are permitted provided that the following conditions are met:
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   1. Redistributions of source code must retain the above copyright notice,
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this list of conditions and the following disclaimer.
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   2. Redistributions in binary form must reproduce the above copyright notice,
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this list of conditions and the following disclaimer in the documentation
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and/or other materials provided with the distribution.
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   3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
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Institute nor the names of its contributors may be used to endorse or promote
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products derived from this software without specific prior written permission.
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THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
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ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
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WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
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DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
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FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
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DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
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SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
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CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
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OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
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OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
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*/
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#define HTS_BUILDING_LIBRARY // Enables HTSLIB_EXPORT, see htslib/hts_defs.h
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#include <config.h>
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#include <stdio.h>
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#include <errno.h>
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#include <assert.h>
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#include <stdlib.h>
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#include <string.h>
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#include <zlib.h>
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#include <sys/types.h>
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#include <sys/stat.h>
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#include <math.h>
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#include <inttypes.h>
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#include "cram.h"
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#include "os.h"
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cram_stats *cram_stats_create(void) {
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    return calloc(1, sizeof(cram_stats));
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}
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int cram_stats_add(cram_stats *st, int64_t val) {
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    st->nsamp++;
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    //assert(val >= 0);
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    if (val < MAX_STAT_VAL && val >= 0) {
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        st->freqs[val]++;
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    } else {
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        khint_t k;
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        int r;
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        if (!st->h) {
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            st->h = kh_init(m_i2i);
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            if (!st->h)
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                return -1;
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        }
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        k = kh_put(m_i2i, st->h, val, &r);
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        if (r == 0)
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            kh_val(st->h, k)++;
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        else if (r != -1)
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            kh_val(st->h, k) = 1;
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        else
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            return -1;
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    }
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    return 0;
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}
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void cram_stats_del(cram_stats *st, int64_t val) {
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    st->nsamp--;
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    //assert(val >= 0);
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    if (val < MAX_STAT_VAL && val >= 0) {
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        st->freqs[val]--;
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        assert(st->freqs[val] >= 0);
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    } else if (st->h) {
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        khint_t k = kh_get(m_i2i, st->h, val);
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        if (k != kh_end(st->h)) {
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            if (--kh_val(st->h, k) == 0)
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                kh_del(m_i2i, st->h, k);
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        } else {
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            hts_log_warning("Failed to remove val %"PRId64" from cram_stats", val);
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            st->nsamp++;
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        }
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    } else {
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        hts_log_warning("Failed to remove val %"PRId64" from cram_stats", val);
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        st->nsamp++;
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    }
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}
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#if DEBUG_CRAM_STATS
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void cram_stats_dump(cram_stats *st) {
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    int i;
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    fprintf(stderr, "cram_stats:\n");
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    for (i = 0; i < MAX_STAT_VAL; i++) {
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        if (!st->freqs[i])
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            continue;
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        fprintf(stderr, "\t%d\t%d\n", i, st->freqs[i]);
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    }
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    if (st->h) {
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        khint_t k;
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        for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
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            if (!kh_exist(st->h, k))
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                continue;
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            fprintf(stderr, "\t%d\t%d\n", kh_key(st->h, k), kh_val(st->h, k));
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        }
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    }
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}
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#endif
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/*
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 * Computes entropy from integer frequencies for various encoding methods and
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 * picks the best encoding.
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 *
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 * FIXME: we could reuse some of the code here for the actual encoding
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 * parameters too. Eg the best 'k' for SUBEXP or the code lengths for huffman.
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 *
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 * Returns the best codec to use.
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 */
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enum cram_encoding cram_stats_encoding(cram_fd *fd, cram_stats *st) {
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    int nvals, i, ntot = 0, max_val = 0, min_val = INT_MAX;
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    int *vals = NULL, *freqs = NULL, vals_alloc = 0;
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#if DEBUG_CRAM_STATS
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    cram_stats_dump(st);
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#endif
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    /* Count number of unique symbols */
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    for (nvals = i = 0; i < MAX_STAT_VAL; i++) {
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        if (!st->freqs[i])
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            continue;
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        if (nvals >= vals_alloc) {
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            vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
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            int *vals_tmp  = realloc(vals,  vals_alloc * sizeof(int));
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            int *freqs_tmp = realloc(freqs, vals_alloc * sizeof(int));
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            if (!vals_tmp || !freqs_tmp) {
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                free(vals_tmp  ? vals_tmp  : vals);
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                free(freqs_tmp ? freqs_tmp : freqs);
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                return E_HUFFMAN; // Cannot do much else atm
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            }
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            vals = vals_tmp;
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            freqs = freqs_tmp;
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        }
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        vals[nvals] = i;
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        freqs[nvals] = st->freqs[i];
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        ntot += freqs[nvals];
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        if (max_val < i) max_val = i;
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        if (min_val > i) min_val = i;
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        nvals++;
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    }
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    if (st->h) {
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        khint_t k;
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        int i;
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        for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
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            if (!kh_exist(st->h, k))
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                continue;
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            if (nvals >= vals_alloc) {
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                vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
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                int *vals_tmp  = realloc(vals,  vals_alloc * sizeof(int));
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                int *freqs_tmp = realloc(freqs, vals_alloc * sizeof(int));
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                if (!vals_tmp || !freqs_tmp) {
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                    free(vals_tmp  ? vals_tmp  : vals);
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                    free(freqs_tmp ? freqs_tmp : freqs);
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                    return E_HUFFMAN; // Cannot do much else atm
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                }
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                vals = vals_tmp;
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                freqs = freqs_tmp;
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            }
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            i = kh_key(st->h, k);
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            vals[nvals]=i;
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            freqs[nvals] = kh_val(st->h, k);
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            ntot += freqs[nvals];
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            if (max_val < i) max_val = i;
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            if (min_val > i) min_val = i;
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            nvals++;
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        }
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    }
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    st->nvals = nvals;
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    st->min_val = min_val;
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    st->max_val = max_val;
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    assert(ntot == st->nsamp);
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    free(vals);
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    free(freqs);
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    /*
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     * Simple policy that everything is external unless it can be
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     * encoded using zero bits as a unary item huffman table.
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     */
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    if (CRAM_MAJOR_VERS(fd->version) >= 4) {
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        // Note, we're assuming integer data here as we don't have the
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        // type passed in.  Cram_encoder_init does know the type and
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        // will convert to E_CONST_BYTE or E_EXTERNAL as appropriate.
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        if (nvals == 1)
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            return E_CONST_INT;
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        else if (nvals == 0 || min_val < 0)
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            return E_VARINT_SIGNED;
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        else
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            return E_VARINT_UNSIGNED;
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    } else {
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        return nvals <= 1 ? E_HUFFMAN : E_EXTERNAL;
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    }
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}
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void cram_stats_free(cram_stats *st) {
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    if (st->h)
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        kh_destroy(m_i2i, st->h);
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    free(st);
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}