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<article article-type="discussion" dtd-version="1.3" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">
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<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">PLoS Biol</journal-id>
<journal-id journal-id-type="publisher-id">plos</journal-id>
<journal-id journal-id-type="pmc">plosbiol</journal-id>
<journal-title-group>
<journal-title>PLOS Biology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1544-9173</issn>
<issn pub-type="epub">1545-7885</issn>
<publisher>
<publisher-name>Public Library of Science</publisher-name>
<publisher-loc>San Francisco, CA USA</publisher-loc>
</publisher>
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<article-meta>
<article-id pub-id-type="doi">10.1371/journal.pbio.3003455</article-id>
<article-id pub-id-type="publisher-id">PBIOLOGY-D-25-02014</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Community Page</subject>
</subj-group>
<subj-group subj-group-type="Discipline-v3">
<subject>Research and analysis methods</subject><subj-group><subject>Research assessment</subject><subj-group><subject>Peer review</subject></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Research and analysis methods</subject><subj-group><subject>Scientific publishing</subject></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Computer and information sciences</subject><subj-group><subject>Software engineering</subject><subj-group><subject>Computer software</subject><subj-group><subject>Open source software</subject></subj-group></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Engineering and technology</subject><subj-group><subject>Software engineering</subject><subj-group><subject>Computer software</subject><subj-group><subject>Open source software</subject></subj-group></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Science policy</subject><subj-group><subject>Open science</subject><subj-group><subject>Open source software</subject></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Computer and information sciences</subject><subj-group><subject>Software engineering</subject><subj-group><subject>Software tools</subject></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Engineering and technology</subject><subj-group><subject>Software engineering</subject><subj-group><subject>Software tools</subject></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Computer and information sciences</subject><subj-group><subject>Artificial intelligence</subject></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Science policy</subject><subj-group><subject>Science and technology workforce</subject><subj-group><subject>Careers in research</subject><subj-group><subject>Scientists</subject></subj-group></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>People and places</subject><subj-group><subject>Population groupings</subject><subj-group><subject>Professions</subject><subj-group><subject>Scientists</subject></subj-group></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Research and analysis methods</subject><subj-group><subject>Database and informatics methods</subject><subj-group><subject>Database searching</subject></subj-group></subj-group></subj-group><subj-group subj-group-type="Discipline-v3">
<subject>Science policy</subject><subj-group><subject>Research funding</subject><subj-group><subject>Research grants</subject></subj-group></subj-group></subj-group></article-categories>
<title-group>
<article-title>When goodbye comes too soon: How to wrap up science projects quickly</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes" equal-contrib="yes" xlink:type="simple">
<contrib-id authenticated="true" contrib-id-type="orcid">https://orcid.org/0000-0002-3715-9475</contrib-id>
<name name-style="western">
<surname>Hagenauer</surname>
<given-names>Megan Hastings</given-names>
</name>
<xref ref-type="aff" rid="aff001"><sup>1</sup></xref>
<xref ref-type="corresp" rid="cor001">*</xref>
</contrib>
<contrib contrib-type="author" equal-contrib="yes" xlink:type="simple">
<name name-style="western">
<surname>Winham</surname>
<given-names>Stacey J.</given-names>
</name>
<xref ref-type="aff" rid="aff002"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author" xlink:type="simple">
<name name-style="western">
<surname>Freeman</surname>
<given-names>Alexandra L. J.</given-names>
</name>
<xref ref-type="aff" rid="aff003"><sup>3</sup></xref>
</contrib>
<contrib contrib-type="author" xlink:type="simple">
<name name-style="western">
<surname>Sternberg</surname>
<given-names>Paul W.</given-names>
</name>
<xref ref-type="aff" rid="aff004"><sup>4</sup></xref>
</contrib>
<contrib contrib-type="author" xlink:type="simple">
<name name-style="western">
<surname>Kolber</surname>
<given-names>Benedict J.</given-names>
</name>
<xref ref-type="aff" rid="aff005"><sup>5</sup></xref>
</contrib>
</contrib-group>
<aff id="aff001"><label>1</label> <addr-line>Michigan Neuroscience Institute (MNI), University of Michigan, Ann Arbor, Michigan, United States of America</addr-line></aff>
<aff id="aff002"><label>2</label> <addr-line>Division of Computational Biology, Mayo Clinic Rochester, Rochester, Minnesota, United States of America</addr-line></aff>
<aff id="aff003"><label>3</label> <addr-line>Octopus Publishing CIC, Abingdon, United Kingdom</addr-line></aff>
<aff id="aff004"><label>4</label> <addr-line>Division of Biology and Biological Engineering, Caltech, Pasadena, California, United States of America</addr-line></aff>
<aff id="aff005"><label>5</label> <addr-line>Department of Neuroscience, University of Texas at Dallas, Richardson, Texas, United States of America</addr-line></aff>
<author-notes>
<corresp id="cor001">* E-mail: <email xlink:type="simple">hagenaue@umich.edu</email></corresp>
<fn fn-type="conflict" id="coi001">
<p>I have read the journal’s policy and the authors of this manuscript have the following competing interests: A.L.J.F. is the creator and director of the not-for-profit platform Octopus.ac. P.W.S. is a founder and Editor-in-Chief of the not-for-profit journal microPublication Biology. S.J.W. is the co-creator of the free web tool Fiddle. M.H.H. and B.J.K. have no competing interests.</p>
</fn>
<fn fn-type="other" id="fn001">
<p>☯ These authors contributed equally to this work.</p>
</fn>
</author-notes>
<pub-date pub-type="epub"><day>21</day><month>10</month><year>2025</year></pub-date>
<pub-date pub-type="collection"><month>10</month><year>2025</year></pub-date>
<volume>23</volume>
<issue>10</issue>
<elocation-id>e3003455</elocation-id>
<permissions>
<copyright-year>2025</copyright-year>
<copyright-holder>Hagenauer et al</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
<license-p>This is an open access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p></license>
</permissions>
<self-uri content-type="pdf" xlink:href="info:doi/10.1371/journal.pbio.3003455">
</self-uri>
<abstract abstract-type="teaser">
<p>Science projects are designed and funded to last several years, but sometimes end prematurely, leading to lost data and effort. We discuss inexpensive solutions for quickly documenting partially finished projects and for publishing “as you go” in an uncertain environment.</p>
</abstract>
<abstract abstract-type="toc">
<p>Science projects are designed and funded on the scale of years, so what happens when researchers need to finish prematurely? This Community Page discusses solutions for quickly documenting partially finished projects, and for publishing ‘as you go’ in an uncertain environment.</p>
</abstract>
<funding-group>
<award-group id="award001">
<funding-source>
<institution-wrap>
<institution-id institution-id-type="funder-id">http://dx.doi.org/10.13039/100000065</institution-id>
<institution>National Institute of Neurological Disorders and Stroke</institution>
</institution-wrap>
</funding-source><award-id>NINDS UE5 NS133011</award-id>
<principal-award-recipient><name name-style="western">
<surname>Kolber</surname><given-names>Benedict J.</given-names></name></principal-award-recipient></award-group>
<funding-statement>National Institute of Neurological Disorders and Stroke (<ext-link ext-link-type="uri" xlink:href="https://www.ninds.nih.gov/" xlink:type="simple">https://www.ninds.nih.gov/</ext-link>, NINDS UE5 NS133011: B.J.K.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.</funding-statement>
</funding-group>
<counts>
<fig-count count="0"/>
<table-count count="1"/>
<page-count count="5"/>
</counts>
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<custom-meta>
<meta-name>PLOS Publication Stage</meta-name>
<meta-value>vor-update-to-uncorrected-proof</meta-value>
</custom-meta>
<custom-meta>
<meta-name>Publication Update</meta-name>
<meta-value>2025-10-24</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
<body>
<p>Science is an assiduous endeavor. Projects are often designed and funded on the scale of years or decades. Even a completed project, fully written up, may spend many months undergoing peer review and revision prior to publication. And painfully, until the work is published, the public impact of complex scientific efforts is minimal.</p>
<p>In such a slow system, what can we salvage when multi-year projects need to end prematurely? This issue has come to the forefront recently due to the rapid reduction of US federal science funding and infrastructure [<xref ref-type="bibr" rid="pbio.3003455.ref001">1</xref>]. However, even under typical circumstances, many well-designed projects are never completed due to a lack of time or funding, and research can be disrupted as a result of career changes, visa issues, or personal circumstances. Transferring responsibility for a project to a collaborator may cause it to stall, or may simply be impossible, especially if the entire project is defunded or the laboratory closes.</p>
<p>Premature project terminations threaten to waste existing public and private investments [<xref ref-type="bibr" rid="pbio.3003455.ref002">2</xref>], and forfeit hard-earned knowledge. There is, therefore, an imperative to establish a scientific record of current progress efficiently and quickly. In this Community Page, we discuss existing venues and resources for rapidly documenting projects that have not reached their natural conclusion, as well as publishing “as you go” to prevent future problems in an uncertain environment. Importantly, these resources allow documentation in a manner that provides credit for individual efforts and accomplishments, enabling future researchers to build on unfinished work.</p>
<sec id="sec001">
<title>Where to publish half-finished projects</title>
<p>Within most scientific disciplines, it is traditional to wait to publish a study until the results provide a strong answer to a research question. However, there is active debate as to whether this is the ideal workflow. Under this model, an estimated 40% of data go unpublished [<xref ref-type="bibr" rid="pbio.3003455.ref003">3</xref>], with a strong skew against publishing negative results [<xref ref-type="bibr" rid="pbio.3003455.ref004">4</xref>]; a source of bias in the scientific literature referred to as “The File Drawer Problem.” Emphasizing a publishable “story” may also encourage questionable research practices, such as the flexible “dredging” of data to achieve statistically significant results (P-hacking), adapting hypotheses to match results (HARK-ing), and the selective reporting of findings (cherry picking) [<xref ref-type="bibr" rid="pbio.3003455.ref005">5</xref>].</p>
<p>In response, there has been a growing movement for “modular publishing,” or sharing smaller component parts of a study as they are produced [<xref ref-type="bibr" rid="pbio.3003455.ref006">6</xref>]. Within this model, components can be publicly released, either in specialized repositories as non-peer-reviewed interim products, or published separately in dedicated peer-reviewed journals (<xref ref-type="table" rid="pbio.3003455.t001">Table 1</xref>). There are also formats that encourage such staging, allowing components to be formally linked or released together, sometimes with opportunity for postpublication peer review and revision (e.g., <ext-link ext-link-type="uri" xlink:href="https://osf.io/" xlink:type="simple">Open Science Framework</ext-link> (OSF), <ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, and <ext-link ext-link-type="uri" xlink:href="https://riojournal.com/" xlink:type="simple">Research Ideas and Outcomes</ext-link>). Individual complete experiments can also be documented in short formats instead of being grouped together to build a larger “story.” In general, publication in specialized repositories is free and rapid (on the scale of days), whereas traditional journal publication is often accompanied by article processing charges and is much slower due to the editorial and peer review process, which may involve reviewer-requested experiments, or rejection and resubmission.</p>
<table-wrap id="pbio.3003455.t001" position="float"><object-id pub-id-type="doi">10.1371/journal.pbio.3003455.t001</object-id><label>Table 1</label><caption><title>Example venues for releasing or publishing products produced at each stage of the research process. In this table, we emphasize existing options that offer unique, persistent digital online identifiers (DOI) and indexing to facilitate product discovery and access. A version of this table can also be found at <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.6084/m9.figshare.29356853.v3" xlink:type="simple">https://doi.org/10.6084/m9.figshare.29356853.v3</ext-link> with updated hyperlinks and relevant additions as they become available.</title></caption>
<alternatives><graphic id="pbio.3003455.t001g" mimetype="image" position="float" xlink:href="info:doi/10.1371/journal.pbio.3003455.t001" xlink:type="simple"/><table><colgroup>
<col align="left" valign="middle"/>
<col align="left" valign="middle"/>
<col align="left" valign="middle"/>
</colgroup>
<thead>
<tr>
<th align="left">Stage of project</th>
<th align="left">Non-peer-reviewed products</th>
<th align="left">Peer-reviewed products</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left"><bold>Hypothesis, research problem, or proposal</bold></td>
<td align="left"><bold><italic>Compatible preprint servers:</italic></bold> <ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.preprints.org/" xlink:type="simple">Preprints.org</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchsquare.com/" xlink:type="simple">ResearchSquare</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Research proposal publication:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://riojournal.com/" xlink:type="simple">Research Ideas and Outcomes</ext-link><break/><bold><italic>Review article:</italic></bold><break/>Most scientific journals (to search: <ext-link ext-link-type="uri" xlink:href="https://jane.biosemantics.org/" xlink:type="simple">Jane</ext-link>)</td>
</tr>
<tr>
<td align="left"><bold>Vetted protocol</bold></td>
<td align="left"><bold><italic>Protocol repositories:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://osf.io/" xlink:type="simple">OSF</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.protocols.io/" xlink:type="simple">Protocols.io</ext-link></td>
<td align="left"><bold><italic>Protocol publication:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://bmcmethods.biomedcentral.com/" xlink:type="simple">BMC Methods</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://f1000research.com/for-authors/article-guidelines/study-protocols" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://gigabytejournal.com/" xlink:type="simple">GigaByte</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.jove.com/" xlink:type="simple">JoVE</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.nature.com/laban/content" xlink:type="simple">Lab Animal</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.nature.com/nprot/" xlink:type="simple">Nature Protocols</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://journals.plos.org/plosone/s/what-we-publish" xlink:type="simple">PLOS One</ext-link></td>
</tr>
<tr>
<td align="left"><bold>Methods paper or technical note</bold></td>
<td align="left"><bold><italic>Compatible preprint servers:</italic></bold> <ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.preprints.org/" xlink:type="simple">Preprints.org</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchsquare.com/" xlink:type="simple">ResearchSquare</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Methods papers or technical notes:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://biologicalproceduresonline.biomedcentral.com/" xlink:type="simple">Biological Procedures Online</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.cell.com/cell-reports-methods/home" xlink:type="simple">Cell Reports Methods</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.sciencedirect.com/journal/methods" xlink:type="simple">Methods</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.sciencedirect.com/journal/methodsx" xlink:type="simple">MethodsX</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.nature.com/nmeth/" xlink:type="simple">Nature Methods</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://journals.plos.org/plosbiology/s/what-we-publish" xlink:type="simple">PLOS Biology</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://journals.plos.org/ploscompbiol/s/submission-guidelines" xlink:type="simple">PLOS Computational Biology</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://jane.biosemantics.org/" xlink:type="simple">Jane</ext-link> and <ext-link ext-link-type="uri" xlink:href="https://en.wikipedia.org/wiki/Category:Research_methods_journals" xlink:type="simple">Wikipedia</ext-link>)</td>
</tr>
<tr>
<td align="left"><bold>Data release or data note</bold></td>
<td align="left"><bold><italic>Data release repositories:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://datadryad.org/" xlink:type="simple">Dryad</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://figshare.com/" xlink:type="simple">figshare</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://data.mendeley.com/" xlink:type="simple">Mendeley Data</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://zenodo.org/" xlink:type="simple">Zenodo</ext-link> (for disciplinary repositories: <ext-link ext-link-type="uri" xlink:href="https://commons.datacite.org/repositories" xlink:type="simple">DataCite</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://fairsharing.org/" xlink:type="simple">FAIRsharing</ext-link> or <ext-link ext-link-type="uri" xlink:href="https://www.re3data.org/" xlink:type="simple">re3data</ext-link>) <break/><bold><italic>Compatible preprint servers:</italic></bold> <ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.preprints.org/" xlink:type="simple">Preprints.org</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchsquare.com/" xlink:type="simple">ResearchSquare</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Data release paper or data note:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://bmcresnotes.biomedcentral.com/" xlink:type="simple">BMC Research Notes</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.mdpi.com/journal/data" xlink:type="simple">Data</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.sciencedirect.com/journal/data-in-brief" xlink:type="simple">Data in Brief</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://f1000research.com/for-authors/article-guidelines/data-notes" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://gigabytejournal.com/" xlink:type="simple">GigaByte</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://open-research-europe.ec.europa.eu/" xlink:type="simple">Open Research Europe</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.nature.com/sdata/" xlink:type="simple">Scientific Data</ext-link> (for others, see this <ext-link ext-link-type="uri" xlink:href="https://zenodo.org/records/7082126" xlink:type="simple">List of Data Journals</ext-link>)</td>
</tr>
<tr>
<td align="left"><bold>Algorithm, tool, or software</bold></td>
<td align="left"><bold><italic>Code or software release repository:</italic></bold> <ext-link ext-link-type="uri" xlink:href="https://codeocean.com/" xlink:type="simple">Code Ocean</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://github.com/" xlink:type="simple">GitHub</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://zenodo.org/" xlink:type="simple">Zenodo</ext-link><break/><bold><italic>Compatible preprint servers:</italic></bold><break/> <ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.preprints.org/" xlink:type="simple">Preprints.org</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchsquare.com/" xlink:type="simple">ResearchSquare</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Tool or software note:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://f1000research.com/for-authors/article-guidelines/software-tool-articles" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://openresearchsoftware.metajnl.com/" xlink:type="simple">Journal of Open Research Software</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://joss.theoj.org/" xlink:type="simple">Journal of Open Source Software</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://journals.plos.org/ploscompbiol/s/submission-guidelines" xlink:type="simple">PLOS Computational Biology</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.sciencedirect.com/journal/softwarex" xlink:type="simple">SoftwareX</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://www.software.ac.uk/top-tip/which-journals-should-i-publish-my-software" xlink:type="simple">The Software Sustainability Institute</ext-link>)</td>
</tr>
<tr>
<td align="left"><bold>Partial analysis, preliminary analysis, or small/limited study</bold></td>
<td align="left"><bold><italic>Poster servers:</italic></bold> <break/><ext-link ext-link-type="uri" xlink:href="https://f1000research.com/for-authors/posters-and-slides-guidelines" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.peeref.com/" xlink:type="simple">PeerRef</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.scienceopen.com/" xlink:type="simple">ScienceOpen</ext-link><break/><bold><italic>Research lecture notes or conference proceedings:</italic></bold> <break/><ext-link ext-link-type="uri" xlink:href="https://arxiv.org/" xlink:type="simple">arXiv</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link><break/><bold><italic>Generalized repositories:</italic></bold><break/> <ext-link ext-link-type="uri" xlink:href="https://figshare.com/" xlink:type="simple">figshare</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://zenodo.org/" xlink:type="simple">Zenodo</ext-link><break/><bold><italic>Short result preprint:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://www.octopus.ac/" xlink:type="simple">Octopus.ac</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Micropublication, brief report, short report, brief communication, or short communication:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://bmcresnotes.biomedcentral.com/" xlink:type="simple">BMC Research Notes</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://f1000research.com/for-authors/article-guidelines/brief-report" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.nature.com/laban/content" xlink:type="simple">Lab Animal</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.micropublication.org/" xlink:type="simple">microPublication.org</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://journals.plos.org/plosbiology/s/what-we-publish" xlink:type="simple">PLOS Biology</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://riojournal.com/" xlink:type="simple">Research Ideas and Outcomes</ext-link>, many field specific journals (see <ext-link ext-link-type="uri" xlink:href="https://jane.biosemantics.org/" xlink:type="simple">Jane</ext-link>)</td>
</tr>
<tr>
<td align="left"><bold>Thesis or dissertation (no time to reformat)</bold></td>
<td align="left"><bold><italic>Compatible preprint servers:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://arxiv.org/" xlink:type="simple">arXiv</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://osf.io/preprints/thesiscommons" xlink:type="simple">OSF Thesis Commons</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchequals.com/" xlink:type="simple">ResearchEquals</ext-link></td>
<td align="left"><bold><italic>Peer-reviewed preprints:</italic></bold> <break/><ext-link ext-link-type="uri" xlink:href="https://peercommunityin.org/" xlink:type="simple">Peer Community in</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://prereview.org/" xlink:type="simple">PREreview</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchhub.com/" xlink:type="simple">ResearchHub</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.scienceopen.com/" xlink:type="simple">ScienceOpen</ext-link> <break/><bold><italic>Post-publication review:</italic></bold><break/> <ext-link ext-link-type="uri" xlink:href="https://riojournal.com/" xlink:type="simple">Research Ideas and Outcomes</ext-link></td>
</tr>
<tr>
<td align="left"><bold>Full manuscript (no time for lengthy peer review)</bold></td>
<td align="left"><bold><italic>All preprint servers:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://arxiv.org/" xlink:type="simple">arXiv</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.biorxiv.org/" xlink:type="simple">bioRxiv</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.preprints.org/" xlink:type="simple">Preprints.org</ext-link> (for others, see <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAPbio</ext-link>)</td>
<td align="left"><bold><italic>Peer-reviewed preprints:</italic></bold> <break/><ext-link ext-link-type="uri" xlink:href="https://elifesciences.org/" xlink:type="simple">eLife</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://peercommunityin.org/" xlink:type="simple">Peer Community in</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://prereview.org/" xlink:type="simple">PREreview</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.researchhub.com/" xlink:type="simple">ResearchHub</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.reviewcommons.org/" xlink:type="simple">Review Commons</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.scienceopen.com/" xlink:type="simple">ScienceOpen</ext-link> <break/><bold><italic>Post-publication review:</italic></bold><break/><ext-link ext-link-type="uri" xlink:href="https://publications.copernicus.org/open-access_journals/life_sciences.html" xlink:type="simple">Copernicus Publications</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://f1000research.com/about" xlink:type="simple">F1000Research</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://open-research-europe.ec.europa.eu/" xlink:type="simple">Open Research Europe</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://www.mdpi.com/journal/sci" xlink:type="simple">Sci</ext-link></td>
</tr>
</tbody>
</table>
</alternatives></table-wrap>
<p>Online tools are available to help match publishing solutions to the needs of the researcher. The online tool <ext-link ext-link-type="uri" xlink:href="https://s-quest.bihealth.org/fiddle/" xlink:type="simple">Fiddle</ext-link> can match scientists with peer-reviewed and non-peer-reviewed options, taking into account individual financing and indexing constraints. The online tools <ext-link ext-link-type="uri" xlink:href="https://jane.biosemantics.org/" xlink:type="simple">Jane</ext-link> and <ext-link ext-link-type="uri" xlink:href="https://journalfinder.elsevier.com/" xlink:type="simple">Journal Finder</ext-link> recommend journals using the abstract text and/or title, and <ext-link ext-link-type="uri" xlink:href="https://transpose-publishing.github.io/" xlink:type="simple">Transpose</ext-link> provides an easy way to search for journals with particular policies that can expedite publishing [<xref ref-type="bibr" rid="pbio.3003455.ref007">7</xref>], including peer review transfers between journals (although this database is no longer actively maintained). <ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">ASAP</ext-link><ext-link ext-link-type="uri" xlink:href="https://asapbio.org/preprint-servers/" xlink:type="simple">bio</ext-link> also hosts a searchable database of preprint servers, and <ext-link ext-link-type="uri" xlink:href="https://www.re3data.org/" xlink:type="simple">re3data</ext-link>, <ext-link ext-link-type="uri" xlink:href="https://fairsharing.org/" xlink:type="simple">FAIR</ext-link><ext-link ext-link-type="uri" xlink:href="https://fairsharing.org/" xlink:type="simple">sharing</ext-link>, and <ext-link ext-link-type="uri" xlink:href="https://commons.datacite.org/repositories" xlink:type="simple">DataCite</ext-link> have extensive guidance regarding field-specific data repositories.</p>
</sec>
<sec id="sec002">
<title>Is there a down-side to releasing research products piecemeal?</title>
<p>There are reasons not to publicly release partially finished projects. Some research may be incompatible with these formats owing to ethical constraints on the public release of human subjects data or sensitive animal data. There may also be concerns that publication of research components may hinder later attempts at traditional publication. To this end, most major journals have begun to welcome, or even encourage, the separate release of study components [<xref ref-type="bibr" rid="pbio.3003455.ref008">8</xref>], as this relieves the final publication of the burden of providing the full study documentation necessary for research reproducibility. The <ext-link ext-link-type="uri" xlink:href="https://en.wikipedia.org/wiki/List_of_academic_publishers_by_preprint_policy" xlink:type="simple">vast majority of journals</ext-link> also welcome manuscripts that have been released as preprints [<xref ref-type="bibr" rid="pbio.3003455.ref007">7</xref>], with some even accepting direct transfer of preprints (and sometimes their reviews) to journal submission systems. In the meantime, these modular research outputs can be reported on CVs and grant applications to illustrate productivity, skills, and dedication to open science practices.</p>
<p>Another concern is that “unfinished” projects may lack replication or validation work. The publication of such data without acknowledging its exploratory nature may lead to wasted future effort. However, if limitations are properly acknowledged, contributing exploratory work to the scientific record can benefit future meta-analyses and encourage replication attempts.</p>
</sec>
<sec id="sec003">
<title>Wrapping things up quickly</title>
<p>Although the options described in <xref ref-type="table" rid="pbio.3003455.t001">Table 1</xref> for modular publishing or preprinting are faster than traditional scientific publications, preparing these products still requires effort and time. All formats require gathering coauthor approval and conflict of interest disclosures, which can take several weeks, and peer-reviewed products will still require both editorial and peer review, and often revision and re-review (for individual journal time estimates, see <ext-link ext-link-type="uri" xlink:href="https://scirev.org/" xlink:type="simple">SciRev.org</ext-link>). Furthermore, the products should be carefully prepared and cleanly formatted, as they will be joining the permanent public record and their utility will depend on the quality of their description.</p>
<p>To this end, scientists who still have access to resources may consider offloading some work onto a <ext-link ext-link-type="uri" xlink:href="https://www.nasw.org/page/services-editors-and-employers" xlink:type="simple">professional science writer</ext-link>, paper reformatting service (e.g., <ext-link ext-link-type="uri" xlink:href="https://www.editage.com/services/research-paper-manuscript-formatting-services" xlink:type="simple">Editage</ext-link>) or scientific editing service (e.g., those offered by <ext-link ext-link-type="uri" xlink:href="https://authorservices.springernature.com/scientific-editing" xlink:type="simple">SpringerNature</ext-link> or <ext-link ext-link-type="uri" xlink:href="https://webshop.elsevier.com/language-editing/" xlink:type="simple">Elsevier</ext-link>). If so, it is important to select a writer or service with suitable training and qualifications, and to <ext-link ext-link-type="uri" xlink:href="https://blog.amwa.org/understanding-authorship-in-a-changing-world" xlink:type="simple">properly define, oversee, and acknowledge</ext-link> their involvement, as ghost authorship is ethically prohibited in most contexts. Moreover, substantial contributions to interpretation may require consideration for full authorship [<xref ref-type="bibr" rid="pbio.3003455.ref009">9</xref>].</p>
<p>Artificial intelligence (AI) tools can also help with browsing literature, summarizing rough notes, digitizing protocols, organizing code or data for release, improving data visualizations, improving grammar, clarity, tone, or conciseness of text, and helping reformat a paper to fit journal requirements [<xref ref-type="bibr" rid="pbio.3003455.ref010">10</xref>]. Researchers need to proceed with AI tools carefully. Some tools will store and reuse inputted data, which is incompatible with sensitive data (e.g., clinical data). It is also important to double-check AI output for inaccuracy, inappropriate use or misinterpretation of source material and hallucinations [<xref ref-type="bibr" rid="pbio.3003455.ref011">11</xref>]. Moreover, the paper must still center on the authors’ own work and ideas, and all AI usage must be carefully documented and transparently disclosed, following journal requirements [<xref ref-type="bibr" rid="pbio.3003455.ref009">9</xref>].</p>
</sec>
<sec id="sec004">
<title>What about money?</title>
<p>Many of the publishing outlets in <xref ref-type="table" rid="pbio.3003455.t001">Table 1</xref> are free, but some charge fees. Ideally, costs such as article processing charges would be charged to grants, as it is in the funders’ best interest for all research products to be publicly shared. If funding is unavailable, it is worth contacting your institution’s library or grants office, if available, to determine if any journals or publishers have an open access agreement or fee waiver for your institution or research society (e.g., the <ext-link ext-link-type="uri" xlink:href="https://btaa.org/library/open-scholarship/agreements" xlink:type="simple">Big 10 Academic Alliance</ext-link>). Many journals also offer <ext-link ext-link-type="uri" xlink:href="https://group.springernature.com/gp/group/media/press-releases/nature-announces-support-for-authors-to-publish-open-access/23894926" xlink:type="simple">fee waivers</ext-link> or reduced charges for researchers from low- and middle-income countries (e.g., <ext-link ext-link-type="uri" xlink:href="https://www.research4life.org/access/eligibility/" xlink:type="simple">Research4Life</ext-link>), or in exchange for reviewing papers.</p>
<p>What about the cost of preparing the publications and research products? At this point, there are few sources of support for scientists interested in cleaning out their file drawers. The American Association of University Women offers grants to <ext-link ext-link-type="uri" xlink:href="https://www.aauw.org/resources/programs/fellowships-grants/current-opportunities/american-dissertation-fellowship-program/" xlink:type="simple">finish dissertation writing</ext-link> or <ext-link ext-link-type="uri" xlink:href="https://www.aauw.org/resources/programs/fellowships-grants/current-opportunities/american-short-term-research-publication-grants/" xlink:type="simple">prepare manuscripts for publication</ext-link>, and publication grants are occasionally available at the institution level. Offering grants to defunded or transitioning researchers for rapid research product release and manuscript preparation would be a high-impact investment for institutions and research foundations, yielding high returns for minimal upfront costs.</p>
</sec>
<sec id="sec005" sec-type="conclusions">
<title>Conclusions</title>
<p>Due to a variety of circumstances, including sudden policy shifts and common personal challenges, many science projects will never be finished, despite years of invested resources and effort. By carefully and strategically documenting scientific work achieved, components of unfinished projects can be salvaged and preserved to benefit future researchers. Moreover, by thoughtfully considering options for modular publishing before they are needed, scientists can be better prepared for unexpected changes to their trajectory and careers.</p>
</sec>
</body>
<back>
<glossary>
<title>Abbreviations</title>
<def-list><def-item><term>AI</term><def><p>artificial intelligence</p></def></def-item><def-item><term>DOI</term><def><p>digital online identifiers</p></def></def-item><def-item><term>OSF</term><def><p>open science framework</p></def></def-item></def-list>
</glossary>
<ack>
<p>These resources were collected as part of a workshop on <italic><italic>Emptying the File Drawer</italic></italic> held at the 2024 Society for Neuroscience Conference<italic>.</italic></p>
</ack>
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