The science behind lifespan extension
As your dog ages, their metabolic health declines. This can undermine your dog's quality of life and lead to multiple age-related diseases. Slowing or even reversing the loss of metabolic health can extend lifespan and maintain quality of life.
The science behind lifespan extension : Metabolic dysfunction As your dog ages, their metabolic health declines. This can undermine your dog's quality of life and lead to multiple age-related diseases. Slowing or even reversing the loss of metabolic health can extend lifespan and maintain quality of life.
What's the science behind lifespan extension Studies have ...
What's the science behind lifespan extension ? Studies have shown that preserving metabolic health — and preventing metabolic dysfunction — can lead to longer, healthier lifespans in dogs. Learn more about the science behind our senior dog drug, LOY-002, on our blog: https:// loyal .dog/MD See less Pages Other Brand Pharmaceuticals Loyal ...
Coinciding with this work, Loyal recently announced progress toward conditional FDA approval for LOY-002, a once-daily pill that targets age-related metabolic dysfunction in senior dogs. If approved, Loyal says it would be the first FDA-authorized drug specifically indicated for lifespan extension in any species. 1
Loyal's LOY
LOY-002 targets age-related metabolic dysfunction in canines aged 10 years and older, weighing at least 14 lbs, aiming to improve their quality of life. Targeting Metabolic Dysfunction in Aging Dogs LOY-002 is designed to combat the effects of aging by addressing metabolic dysfunction , a key factor in the decline of health in senior dogs.
LOY-002 targets metabolic dysfunction , a core driver of the diseases many senior dogs experience as they age. By addressing the root cause, LOY-002 aims to extend lifespan and maintain quality of life for longer.
Lifespan extension drug in development for senior dogs reaches ...
A drug in development for healthy lifespan extension in senior canines has reached a new milestone on the path toward potential FDA approval. The conditional approval application for the drug LOY-002, created by Loyal , has had its target animal safety (TAS) technical section accepted by the federal agency, according to the biotechnology animal ...
Loyal stated its intention in developing the drug was to address " metabolic dysfunction " in senior dogs, which they defined as "a set of interconnected processes that contribute to poor metabolic ...
The Pill That Could Give Your Dog More Time
The biology of aging in dogs mirrors that in humans more than you might think. Metabolic dysfunction , IGF-1 signaling, cellular senescence…these aren't just canine concerns. They're human ones, too. In fact, some longevity researchers believe dogs are the perfect testbed for anti-aging drugs that could eventually apply to us.
The STAY Trial Loyal's STAY clinical trial enrolled approximately 1,300 senior dogs across multiple veterinary sites — making it the largest veterinary clinical trial in history. The trial assesses whether LOY-002 extends healthy lifespan in senior dogs by tracking survival, disease events, quality of life, and biomarker trajectories.