Overview of Exendin 4 Conjugated Manganese Magnetism Engineered Iron Oxide

To specifically detect and trace transplanted islet β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron oxide nanoparticles (MnMEIO NPs) with exendin-4 (Ex4) which specifically binds glucagon-like peptide-1 ...

To specifically detect and trace transplanted islet β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron oxide nanoparticles (MnMEIO NPs) with exendin-4 (Ex4) which specifically binds glucagon-like peptide-1 receptors on the surface of β-cells. The size distribution of MnMEIO and MnMEIO-Ex4 NPs were 67.8 ± 1.3 and 70.2 ± 2.3 nm and zeta potential ...
Key Details About Exendin 4 Conjugated Manganese Magnetism Engineered Iron Oxide

PDF | To specifically detect and trace transplanted islet β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron ... | Find, read and cite all the research ...
A new class of iron oxide NPs, mag - netism-engineered iron oxide (MEIO) NPs, has been created with high and tunable na- nomagnetism [45]. These MEIO NPs were doped with manganese (MnMEIO NPs) to ...

Useful Notes on Exendin 4 Conjugated Manganese Magnetism Engineered Iron Oxide
To specifically detect and trace transplanted islet β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron oxide ...
The synthesized exendin-4 conjugated magnetic iron oxide -based nanoparticle probe targeting glucagon-like peptide 1 receptor, which is highly expressed on the surface of pancreatic β-cells, has the potential for monitoring the disease development and response of T1D to therapy.

Overview of Exendin 4 Conjugated Manganese Magnetism Engineered Iron Oxide
To detect and trace transplanted β-cells by magnetic resonance imaging (MRI), we conjugated manganese magnetism-engineered iron oxide (MnMEIO) nanoparticles with exendin-4 (MnMEIO-Ex4) which can specifically bind glucagon-like peptide-1 receptors on β-cells.
Recently, we have shown that manganese magnetism-engineered iron oxide nanoparticles (MnMEIO NPs) conjugated with exendin-4 (Ex4) act as a contrast agent that directly trace implanted mouse islet β-cells by magnetic resonance imaging (MRI). Here we further advanced this technology to track implanted porcine neonatal pancreatic cell clusters (NPCCs) containing ducts, endocrine, and exocrine ...

Key Details About Exendin 4 Conjugated Manganese Magnetism Engineered Iron Oxide
Exendin-4-Conjugated Manganese Magnetism-Engineered Iron Oxide Nanoparticles as a Potential Magnetic Resonance Imaging Contrast Agent for Tracking Transplanted β-Cells







Abstract:Recently, we have shown that manganese magnetism-engineered iron oxide nanoparticles (MnMEIO NPs) conjugated with exendin-4 (Ex4) act as a contrast agent that directly trace implanted mouse islet β-cells by magnetic resonance imaging (MRI). Here we further advanced this technology to track implanted porcine neonatal pancreatic cell clusters (NPCCs) containing ducts, endocrine, and ...