Microbiome and Postbiotics in Skin Health
The resident skin microbiome, an ecosystem of bacteria , fungi, viruses, and archaea, plays a vital role in maintaining skin homeostasis and health [31]. The microbiome supports the skin by producing AMPs, regulating pH, and metabolizing sebum, the skin's natural oil [5].
Bacteriophages infecting skin bacteria may influence community composition and gene exchange, with healthy individuals harboring distinct phage populations compared to those with skin diseases. Microscopic arthropods such as Demodex mites inhabit hair follicles and sebaceous glands, feeding on sebum and interacting with both bacteria and fungi.
The human skin microbiome
Furthermore, visual representations like the one above help us fully grasp the concept of Regulating Skin Bacteria.
The skin microbiome is composed of a diverse community of microorganisms, including bacteria , fungi, viruses and mites. These microorganisms have a crucial role in maintaining skin health ...
Commensal bacteria of the genus Cutibacterium, which normally dominate healthy seborrheic skin , are significantly reduced in affected areas. Their presence is associated with improved skin hydration, sebum homeostasis, and the ability to produce bacteriocins that inhibit Staphylococcus growth.
Conversation between skin microbiota and the host
The human skin microbiome is a complex ecosystem of bacteria , fungi, and viruses that plays a vital role in maintaining skin health and protecting against pathogens. Disruptions in the delicate balance of the skin microbiome have been implicated in various dermatological disorders, including atopic dermatitis, acne, rosacea, and psoriasis.
The Skin Microbiome Revolution
Skin flora, also called skin microbiota, refers to microbiota (communities of microorganisms) that reside on the skin , typically human skin . Many of them are bacteria of which there are around 1,000 species upon human skin from nineteen phyla. [1][2] Most are found in the superficial layers of the epidermis and the upper parts of hair follicles.
Human skin bacterial microbiota homeostasis
As the largest organ of the body, the skin acts as a barrier to prevent diseases and harbors a variety of beneficial bacteria . Furthermore, the skin bacterial microbiota plays a vital role in health and disease. Disruption of the barrier or an imbalance between symbionts and pathogens can lead to skin disorders or even systemic diseases. In this review, we first provide an overview of research ...
Maintaining the balance between the host and commensal microorganisms is essential for skin health. The disruption of this equilibrium (dysbiosis) can contribute to inflammatory and infectious diseases and accelerate skin aging. Dysbiosis also accompanies skin cancers and may influence their progression. Causes of dysbiosis include exogenous factors such as cosmetics, UV radiation, pollution ...
