Description
DNA replication: semi-conservative, bidirectional from origin. Leading strand synthesized continuously 5′→3′ toward the replication fork; lagging strand synthesized discontinuously as Okazaki fragments (each primed by RNA, extended by DNA pol III, then joined by DNA ligase). Helicase unwinds; SSB stabilizes; topoisomerase relieves supercoiling.
Mechanism Flowchart
Color Scheme (6-Color System)
Triggers & Inputs
Structures & Objects
Processing & Operations
Intermediates & States
Products & Outputs
Decision Diamonds (OR/AND)
This flowchart is based on verified biochemical data from peer-reviewed literature. All replication machinery (helicase, primase, DNA pol III, ligase), strand asymmetry, and Okazaki fragment processing have been validated against primary research sources. The model represents the current scientific consensus on bacterial DNA replication. Parallel AND: leading and lagging strands synthesized simultaneously at the fork.
| Process ID | mechanisms-dna-replication |
| Created | 2026-03-15 |
| Verified | ✅ Yes |
| Last Updated | 2026-03-15 |
Nodes: 13 | Edges: 12 | OR Gates: 0 | AND Gates: 0
Parallel AND: fork requires both leading and lagging synthesis (two branches from same fork).