Description
Krebs cycle: mitochondrial matrix pathway. Acetyl-CoA enters; oxaloacetate condenses to citrate; eight steps regenerate OAA and release 2 CO2, 3 NADH, 1 FADH2, 1 GTP per turn. Central hub for energy extraction and biosynthetic precursors (e.g., α-ketoglutarate for amino acids, oxaloacetate for gluconeogenesis).
Pathway Flowchart
Color Scheme (6-Color System)
Triggers & Inputs
Structures & Objects
Processing & Operations
Intermediates & States
Products & Outputs
Decision Diamonds (OR/AND)
This flowchart is based on verified biochemical data from peer-reviewed literature. All enzymatic steps, intermediates, and cofactor requirements have been validated against primary research sources and standard biochemistry textbooks. The model represents the current scientific consensus on the citric acid cycle as the central metabolic hub. Sequential AND: acetyl-CoA and oxaloacetate both required for citrate formation (shown as two inputs to citrate synthase).
| Process ID | pathways-krebs-cycle |
| Created | 2026-03-15 |
| Verified | ✅ Yes |
| Last Updated | 2026-03-15 |
Nodes: 18 | Edges: 18 | OR Gates: 0 | AND Gates: 0
Sequential AND: Acetyl-CoA and Oxaloacetate both required for citrate (convergence at citrate synthase); shown as two edges into one node, not a diamond.