Light Microscopic Sciatic Nerve Changes in Control Beagle Dogs from ...
Although the dog is a common choice among nonrodent species in evaluation of compound safety for regulatory submission, information regarding the incidence of spontaneous or incidental microscopic changes in canine peripheral nerve is limited. A retrospective examination was performed of routine histologic preparations of sciatic nerve from eighty-one control dogs in toxicity studies ranging ...
Control purpose-bred beagle dogs can have a range of spontaneous background changes in sciatic nerve sections. To distinguish incidental changes from those related to compound, careful attention to detail and knowledge of characteristics and incidence of spontaneous changes are important.
(PDF) Light Microscopic Sciatic Nerve Changes in Control
Light Microscopic Sciatic Nerve Changes in Control Beagle Dogs From Toxicity Studies by Katharine M. Whitney, Annette J. Schwartz Sterman, Jackie
Whitney, K. M., Schwartz Sterman, A. J., O'Connor, J., Foley, G. L., & Garman, R. H. (2011). Light Microscopic Sciatic Nerve Changes in Control Beagle Dogs from ...
Representative foci of change within canine nerve fibers. (A) Typical ...
Scale bars: 50 mm (A-D), 100 mm (E). from publication: Light Microscopic Sciatic Nerve Changes in Control Beagle Dogs from Toxicity Studies | Although the dog is a common choice among nonrodent ...
The morphology of Renaut bodies ( light microscopy, histochemistry, immunohistochemistry and transmission electron microscopy) in the Beagle dog will be discussed, as well as their biological significance. 0940-2993/01/53/01-019 $ 15.00/ 19 Materials and methods The sciatic nerves of control Beagle dogs from 23 historical Bayer studies (14 ...
Renaut bodies in the sciatic nerve of beagle dogs
Summary 182 control Beagle dogs from 23 historical studies (14 chronic, 9 subchronic) were reviewed histologically for the presence of Renaut bodies in the sciatic nerve . Renaut bodies were found in 36.1 percent of the subchronic-study dogs and in 46.4 percent of the chronic-study dogs .
SUMMARY REPORT (R041) - by Moderator Dr. Byron Boysen Dogs , Beagle , CD-1, Axonal Spheroids, Spontaneous LIGHT MICROSCOPIC DIAGNOSES: Axonal spheroids, diencephalon (thalamus), metencephalon (cochlear nucleus), and myelencephalon (cuneate nucleus), Beagle dog . Axonal spheroids, myelencephalon (gracilis nucleus), CD-1 mouse. CONFERENCE NOTES: The contributor has provided a brief summary of the ...
Beagle sciatic nerve regeneration across a 30 mm defect bridged by ...
Longitudinally oriented microstructures are essential for a nerve scaffold to promote the significant regeneration of injured peripheral axons across nerve gaps. In the current study, we present a novel nerve -guiding collagen-chitosan (CCH) scaffold that facilitated the repair of 30 mm-long sciatic nerve defects in beagles . The CCH scaffolds were observed with a scanning electron microscope ...
Longitudinally oriented microstructures are essential for a nerve scaffold to promote the significant regeneration of injured peripheral axons across nerve gaps. In the current study, we present a novel nerve -guiding collagen-chitosan (CCH) scaffold that facilitated the repair of 30 mm-long sciatic nerve defects in beagles . The CCH scaffolds were observed with a scanning electron microscope ...