Feline Leukemia Virus Predictive Value Of Tests

Feline leukemia virus point

Abstract This study aimed to determine the true prevalence of feline leukemia virus (FeLV) infections in apparently healthy and sick shelter cats in Mississippi and estimate the predictive value of a lateral flow test results at the estimated true prevalences to guide testing recommendations.

Feline Leukaemia Virus FeLV Antigen ELISA

Antigen ELISA and immunochromatography are common used tests to diagnose FeLV infection and are valid screening tests with good sensitivity and specificity. However as the prevalence of disease is low, the positive predictive value (PPV) of these tests is poor (50%) increasing the likelihood of false positive results.

Feline leukemia virus (FeLV) significantly impacts feline health worldwide. Although several FeLV antigen rapid tests are available, selecting an accurate diagnostic tool remains a clinical challenge. In this paper, we present a novel and robust point- of -care assay that enables the precise diagnosis of FeLV antigen in blood, plasma, and serum and directly compared it with five other ...

Performance of 4 Point

Note: As the prevalence of FeLV infection decreases in a given cat population, the percentage of positive antigen test results that are false positives increases (i.e. the positive predictive value of the test result will decrease). Thus, a positive test result in a healthy cat should always be confirmed, preferably by proviral PCR.