Glp 1 And Fasting Induced Changes In Oxidative Stress
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Association of fasting glucagon
Aim: The present study was designed to study the circulating fasting level of total GLP-1 in Type 2 diabetes mellitus (T2DM) patients compared to control subjects and to assess the GLP-1 effect on oxidative stress , atherosclerotic vascular changes (measured by Carotid IMT and ABPI) and other cardio-metabolic risk factors.
Effects of Glucagon
Glp 1 And Fasting Induced Changes In Oxidative Stress
Nrf2 is a master regulator of cellular stress responses, induces the expression of antioxidant and detoxification enzymes, and protects against oxidative stress - induced cell damage. Glucagon-like peptide-1 ( GLP-1 ) is an incretin hormone, which was originally found to increase insulin synthesis and secretion.
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Glp 1 And Fasting Induced Changes In Oxidative Stress
The aim of this work was to evaluate the effects of glucagon-like peptide-1 ( GLP-1 ) on high-glucose- induced oxidative stress and investigate the possible mechanisms underlying this process.
However, a hypothesis involving oxidative stress (OS) and inflammation as potent causative initiators of diabetic complications in general has been put forward [4, 5]. Glucagon-like peptide-1 ( GLP-1 ) constitutes a relatively recent therapeutic option for type 2 diabetic patients.
