Overview of Anti Inflammatory Drugs For Elevated Prostate Specific Antigen Levels
This trial tests whether common anti-inflammatory medications like ibuprofen and naproxen can lower elevated prostate-specific antigen (PSA) levels in men. Elevated PSA levels often lead to prostate biopsies, but sometimes cancer is absent, and inflammation might be the cause.
PSA test can be elevated due to reasons other than cancer such as inflammation or natural variation in the level . Investigators plan to treat men with elevated PSA level with over the counter anti-inflammatory medications (ibuprofen, naproxen) to see if the PSA level will decrease to an acceptable level .
Key Details About Anti Inflammatory Drugs For Elevated Prostate Specific Antigen Levels
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Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen Results from the 2001-2002 National Health and Nutrition Examination Survey Eric A. Singer MD, MA Department of Urology, University of Rochester Medical Center, Rochester, New York Ganesh S. Palapattu MD
Official answer: Some medications can increase levels of prostate-specific antigen (PSA) in the blood, falsely indicating the presence...
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Full description Serum prostate-specific antigen (PSA) is widely used as a screening marker for prostate cancer. However, elevated serum PSA level could result from various conditions other than malignancy such as benign prostatic hyperplasia (BPH), urinary tract infection, or inflammation (prostatitis).
What Medications Can Increase PSA Levels
Certain anti-inflammatory and herbal medications Some non-steroidal anti-inflammatory drugs (NSAIDs) and herbal supplements, particularly those containing saw palmetto, can influence PSA levels . Saw palmetto in particular has been shown to suppress PSA similarly to 5-alpha-reductase inhibitors, which may mask elevated readings.
An elevated PSA ( prostate-specific antigen ) level can be a sign of prostate cancer. Talk to a healthcare provider to see if you should have regular PSA tests.
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