Cognitive dysfunction in systemic lupus erythematosus
Despite the high reported prevalence and burden of cognitive dysfunction in systemic lupus erythematosus (SLE), there is poor understanding of its aetiology, clinical assessment, and management. In part, this lack of understanding is due to conceptual disorganisation in the available literature. In this Review, we address key knowledge gaps in the nomenclature, assessment, and interpretation ...
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease that is associated with considerable morbidity and reduced life expectancy. 1 Symptoms of cognitive dysfunction are distressing for patients with SLE,2, 3 and objectively defined cognitive dysfunction is associated with a negative effect on daily function and ...
Cognitive dysfunction in systemic lupus erythematosus
Despite the high reported prevalence and burden of cognitive dysfunction in systemic lupus erythematosus (SLE), there is poor understanding of its aetiology, clinical assessment, and management.
Raghunath S, Glikmann- Johnston Y, Hanly JG, et al. Cognitive dysfunction in systemic lupus erythematosus : how do we advance our understanding? The Lancet Rheumatology 2022;4:e293-302.
Cognitive Dysfunction in Systemic Lupus Erythematosus ...
Cognitive dysfunction (CD) is a common yet often clinically subtle manifestation that considerably impacts the health-related quality of life in patients with systemic lupus erythaematosus (SLE). Given the inconsistencies in CD assessment and challenges in its attribution to SLE, the reported preval …
Abstract Abstract Systemic lupus erythematosus (SLE) is an autoimmune-mediated collagen disease that results in multiorgan failure. It is the collagen disease most frequently associated with neuropsychiatric symptoms, which have been hypothesized to stem from certain types of cognitive dysfunction .
Altered cognitive function in systemic lupus erythematosus and ...
Cognitive dysfunction (CD) is common in systemic lupus erythematosus (SLE) but the cause remains unclear and treatment options are limited. We aimed to compare cognitive function in SLE and healthy controls (HCs) using both behavioural and neuroimaging techniques.
Cognitive dysfunction in SLE is common, but clinical risk factors are poorly understood. This study aims to explore the associations of cognitive dysfunction in SLE with disease activity, organ damage, biomarkers and medications. We performed ...
Lupus Cognitive Impairment
Lupus cognitive impairment is a disruption in memory, attention, processing speed, and language that occurs when systemic lupus erythematosus affects the brain, either through inflammation of blood vessels, autoantibodies crossing into neural tissue, or the sheer physiological toll of chronic disease activity.
Introduction Neurocognitive changes may hinder the autonomy and independence of patients diagnosed with Systemic Lupus Erythematosus (SLE), being considered as one of the main negative outcomes. Objectives To evaluate the cognitive functions of patients diagnosed with active SLE and in remission at the Rheumatology Outpatient Clinic of the Hospital das Clínicas, School of Medicine ...