Ivermectin Use in Cats: Hidden Seizure Risk Explained
By Kristen Payne · May 16, 2026
Ivermectin Toxicity in Cats
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Unlocking the Mechanism of Ivermectin Toxicity Most veterinarians and veterinary students understand that ivermectin can overstimulate GABA receptors, leading to central nervous system (CNS) depression. Yet, the appearance of tremors or seizures in poisoned cats has baffled many pet owners.
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Ivermectin is a medication commonly used for dogs and livestock but can be harmful to cats . Key symptoms of ivermectin toxicity include vomiting, drooling, tremors, seizures , and lethargy. It's crucial to observe your cat and contact a veterinarian right away if you notice any of these signs.
Most Common Causes of Toxin Seizures in Cats
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Acetaminophen is a potent inducer of methemoglobinemia, especially in cats . Seizures may be seen secondary to hypoxia in patients with methemoglobinemia. Ivermectin and Moxidectin are in the avermectin family of anthelmintics. At supratherapeutic dosages, variety of CNS signs can be seen, including depression, ataxia and seizures .
This article unravels the complexities behind ivermectin toxicity in cats , highlighting symptoms and safe treatment practices. Unlocking the Mechanism of Ivermectin Toxicity Most veterinarians and veterinary students understand that ivermectin can overstimulate GABA receptors, leading to central nervous system (CNS) depression.
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Ivermectin for Cats
But your veterinarian might also prescribe ivermectin for a variety of other parasites, including ear mites and scabies. Ivermectin comes in tablet, liquid (for use in the ear), and injectable forms. Ivermectin is quite safe for cats when used at recommended doses but can have serious side effects at high doses.
Read this toxicology article by Vera M. Steinbergen. Content contains information on clinical signs, treatment, and more.
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Ivermectin toxicity in a cat
In this VETgirl online veterinary continuing education blog, we review ivermectin toxicity in a cat . Intravenous lipid emulsion may be used as treatment.
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