Project

MitoBrainMap is a high-resolution brain-wide map of mitochondrial distribution and specialization based on biochemical and molecular mitochondrial phenotypes assessed on frozen human brain tissue voxels. The resulting probabilistic mitochondrial map bridges the gap between molecular energy landscapes and neuroimaging data to advance our understanding of the energy landscape underlying brain health, with implications for tracing the origin of neurodegenerative and neuropsychiatric disorders.