Overview of Exendin 4 Cas 141758 74 9 Glp 1 Activator
Background on Exendin-4 Exendin-4 , a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors.
Exendin-4 is a 39-amino-acid polypeptide (48-86) and a long-acting glucagon-like peptide-1 ( GLP-1 ) receptor agonist with an IC50 of 3.22 nM.
Key Details About Exendin 4 Cas 141758 74 9 Glp 1 Activator
Exenatide ( Exendin-4 ), a bioactive peptide composed of 39 amino acids, is antidiabetic medication acting as a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.
Exendin-4 (Exenatide) ( CAS : 141758-74-9 ) (ab120214) is a incretin mimetic and composed of 39 amino acids. Exendin-4 is a long-acting glucagon-like peptide-1 ( GLP-1 ) receptor agonist. MW 4187. - Available in different sizes to fit your experimental needs. Larger volume format available upon request
Useful Notes on Exendin 4 Cas 141758 74 9 Glp 1 Activator
Buy Exendin-4 ( CAS 141758-74-9 ) from BenchChem. BBB-permeable GLP -1R agonist with intrinsic DPP-4 resistance for neuroprotection & metabolic research. In stock, global shipping.
Exendin-4 (Exenatide) is a synthetic incretin mimetic peptide and a GLP-1 receptor agonist used in type 2 diabetes, obesity, and metabolic research.
Overview of Exendin 4 Cas 141758 74 9 Glp 1 Activator
Exendin-4 mimics the activity of mammalian incretin hormone glucagon-like peptide 1 ( GLP-1 ), and thus, functions in the control of glucose. This includes the secretion of insulin in a glucose dependent manner, negative regulation of high glucagon secretion, and increased duration of stomach emptying.
Exendin-4 ( CAS 141758-74-9 ) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices ...
Key Details About Exendin 4 Cas 141758 74 9 Glp 1 Activator
Exendin-4 is an incretin mimetic peptide and an analog of glucagon-like peptide 1 ( GLP-1 ). The mimetic activity of Exendin-4 controls insulin secretion in a glucose-dependent manner.
Biological Activity for Exendin-4 Exendin-4 is a high affinity glucagon-like peptide 1 ( GLP-1 ) receptor agonist (K d = 136 pM); originally isolated from Heloderma suspectum venom. Exendin-4 potently induces cAMP formation without stimulating amylase release in pancreatic acini. Potentiates glucose-induced insulin secretion in isolated rat islets.