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All Learn guides · 16 evidence-checked explainers

The oral microbiome & probiotics

  • The Oral Microbiome
  • Oral Probiotics
  • BLIS K12 & M18
  • Lactobacillus reuteri for Oral Health
  • Oral Postbiotics vs Probiotics vs Prebiotics, Explained
  • Oral Thrush and Probiotics

Gum health

  • Gum Disease
  • Gingivitis
  • Receding Gums
  • Bleeding Gums

Bad breath

  • Bad Breath
  • Tonsil Stones

Tooth decay & enamel

  • Tooth Decay & Cavities
  • How to Remineralize Teeth

Everyday concerns

  • Tooth Sensitivity
  • Dry Mouth
Scam Checks
DentaSmile ProDentaViveRenewDentalBioDentexOradentum
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Home
Reviews, current sectionAll reviews →ProDentimProvaDentDentiCoreDentaBiomeSynadentixSteel Bite ProPowerBiteDentolynPurDentix
Best OfAll best of →Best Oral ProbioticsProbiotics for Bad BreathBest Supplements for Receding GumsBest Supplements for Tooth Decay & Enamel Support
LearnAll learn →

The oral microbiome & probiotics

The Oral MicrobiomeOral ProbioticsBLIS K12 & M18Lactobacillus reuteri for Oral HealthOral Postbiotics vs Probiotics vs Prebiotics, ExplainedOral Thrush and Probiotics

Gum health

Gum DiseaseGingivitisReceding GumsBleeding Gums

Bad breath

Bad BreathTonsil Stones

Tooth decay & enamel

Tooth Decay & CavitiesHow to Remineralize Teeth

Everyday concerns

Tooth SensitivityDry Mouth
Scam ChecksDentaSmile ProDentaViveRenewDentalBioDentexOradentum
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Home/Reviews/PurDentix

Reviews

PurDentix Review: A 4-Strain Oral Probiotic, Compared to ProDentim

PurDentix closely mirrors ProDentim on the disclosed label. BL-04 is identified, while the other probiotic species lack exact strain codes and all per-species doses remain hidden. This review separates those label facts from strain-specific evidence.

Eduardo Silva

By Eduardo Silva · Founder & Product Tester

How we test · Evidence-reviewed ·Updated Jul 17, 2026 ·9 min read

Our verdict6.8/10
Official PurDentix bottle

A legitimately sold product whose formula mirrors ProDentim; the evidence is modest and strain-specific, so it works best as an optional add-on to brushing, flossing and professional care.

See the official offer

Affiliate link. We may earn a commission at no cost to you. How this works.

Buy from the official channel for the tested formula + refund guarantee. Price may show below; we never push a single bottle.

How the verdict was scored

Score breakdown

6 factors How we test
Verdict factor scores and their supporting rationale
FactorScoreWhy
Formula & doses vs the studies6.0/10 out of 10The label prints inulin and total blend amounts, but most strain codes and all per-species doses remain hidden.
Strength of the ingredient evidence7.0/10 out of 10Named-strain oral-probiotic studies exist, but the strongest cited strains are absent or unidentified on this label.
Label honesty & third-party testing6.0/10 out of 10BL-04, milk and sucralose are disclosed, but vendor facility badges lack a public certificate number and most strain details remain opaque.
Hands-on results & tolerability8.0/10 out of 10The 21-day notes record fresher breath and cleaner mouthfeel, one missed-dose fade and no side effects.
Price per day & value7.0/10 out of 10The 30-day one-a-day format is clear, but a current live price was not documented in the reviewed sources.
Company transparency, guarantee & checkout7.0/10 out of 10The official offer states a 60-day guarantee, while certificate and physical-return details remain partly vendor-attributed.

Calculation: 41.0 points ÷ 6 scored factors = 6.8/10.

The short version

  • Read the label and PurDentix is a near-mirror of ProDentim, same 100 mg inulin and the same 3.5 billion CFU four-strain blend
  • The effect is real but modest, and the studied strains work best as an add-on to a dentist's cleaning, not on their own
  • The official offer states a 60-day money-back guarantee; the 180-day number is the six-bottle supply, not the refund window
  • BL-04 is identified, but the other three probiotic species lack exact strain codes; per-species doses are hidden, and the formula contains milk plus sucralose
On this page 18 sections
  1. My hands-on read
  2. A near-mirror of ProDentim
  3. Unboxing and what the label actually says
  4. The strains and prebiotic, and what the evidence really says
  5. What the available user evidence can tell us
  6. Complaints and negatives
  7. Is PurDentix a scam?
  8. PurDentix versus ProDentim: which one?
  9. The honest verdict
  10. Frequently asked questions
  11. Offer, certification and safety sources
  12. What's inside vs the evidence
  13. Pros & cons
  14. Official channel vs Amazon & eBay resellers
  15. The offer & the catches
  16. Where to buy & price
  17. References
  18. Who's behind this

My hands-on read

Preliminary read

A cleaner-feeling mouth and clearly fresher morning breath by the second week were the honest highs of my 21-day run; a stubborn gum spot never budged, and the benefit faded the day I skipped a dose.

21day log
1chewable/day
4strains

What I measured

Baseline, final result and measurement method by category
CategoryBaselineFinalHow I measured it
Test window & routineN/A21 days; one chewable dailyHistorical log; no formal baseline week was collected.
AdherenceNot formally countedOne missed dose recorded and perceived benefit faded that dayFull pill count was not collected.
Baseline & methodNo 7-day baselineDays 1-7 logged before the first breath changeHistorical diary; no fixed 0-10 scale.
BreathNot formally ratedNoticeably fresher from week 2Self-report; no numeric scale.
MouthfeelNot formally ratedCleaner after the tablet, plateauing by week 3Self-report; no numeric scale.
Gums & teethOne stubborn gum spotNo changeSelf-report; no clinical gum or enamel measurements.
TolerabilityNo formal baselineMild peppermint, faint chalky finish and no side effects in the notesAdverse events were not formally counted.
Product dimensionsNot formally measuredNot formally measuredNo ruler or caliper measurements were recorded.
Unboxing & first impression
A chewable mint tablet, one a day. Mild peppermint, slightly sweet, with a faint chalky finish before it fully dissolves.
Days 1 to 7
Mouth felt cleaner right after the tablet. Nothing dramatic yet, and no side effects.
Week 2, the turn
Morning breath was noticeably fresher. Subtle, but it repeated enough that I trusted it.
Week 3, plateau
The fresher-breath effect held but didn’t grow, the gum spot I was watching never changed, and the benefit faded on a day I forgot a dose.

My photos from testing PurDentix.

White PurDentix bottle, cap off, blue label reading Supports Healthy Teeth & Gums and 30 chewable tablets, on cream cloth Save
My own bottle with the cap off. You can read '30 chewable tablets' right on the label.
PurDentix bottle tipped on its side with round off-white chewable tablets spilled onto olive-green fabric Save
The chewables I actually poured out: round, off-white discs with a slightly chalky look.

A near-mirror of ProDentim

Here is the finding that reframes the whole review: PurDentix’s disclosed Supplement Facts panel is a near-mirror of ProDentim’s. That label similarity does not prove the same manufacturer, lot quality or finished-product performance.

A quick vocabulary check before the table, because these words do the heavy lifting. A probiotic is a live “friendly” bacterium you take on purpose. A prebiotic is fiber that feeds those bacteria. CFU (colony-forming units) is just a count of how many live bacteria you get per dose. A strain is the exact sub-type of a species, and as you will see, the strain is what actually matters.

ProDentim PurDentix
Inulin (chicory root) 100 mg 100 mg
Total CFU 3.5 billion 3.5 billion
Core strains L. paracasei, L. reuteri, B. lactis BL-04, S. salivarius L. paracasei, L. reuteri, B. lactis BL-04, L. salivarius
Base tricalcium phosphate, MCC, peppermint tricalcium phosphate, MCC, peppermint
Form chewable tablet chewable tablet
Guarantee 60 days 60 days
Independently verified certification none found none found

The only real formula difference is one letter. ProDentim lists an S. salivarius (a Streptococcus, dosed separately); PurDentix lists an L. salivarius (a Lactobacillus) inside its 40 mg blend. Everything else, the prebiotic dose, the CFU count, the other three strains, and the base, is the same.

So the honest headline is simple. If you want this style of oral probiotic, ProDentim and PurDentix deliver nearly the same idea. You are choosing on brand, price and exact label, not on a proven superior formula. The official PurDentix page currently gives the same 60-day refund window as ProDentim. The “180-day” wording beside the largest pack refers to the supply duration, not a six-month guarantee. If you are cross-shopping, my ProDentim review covers the twin, and the best oral probiotics roundup puts the category in order.

Highlighted PurDentix refund-policy page stating a 60-day money-back guarantee Save
Vendor terms The current PurDentix refund page states 60 days. ‘180-day supply’ elsewhere describes the six-bottle quantity, not the refund window. Source: Official PurDentix commercial channel · Captured 2026-07-17. Highlight added by OralRadar. Affiliate link. If you buy, we may earn a commission at no extra cost to you. How this works.

Unboxing and what the label actually says

The front of the bottle leans on marketing language: “Supports Healthy Teeth & Gums” and “Clinically Studied Ingredients.” Treat those as the vendor’s claims, not settled facts. “Clinically studied” refers to some of the ingredient types, not to a trial of this finished product, and no published study has tested PurDentix itself.

Highlighted PurDentix Supplement Facts showing 100 mg inulin, a 40 mg probiotic blend with 3.5 billion CFU, BL-04 and a Contains Milk statement Save
Official label The current label identifies BL-04, 100 mg of inulin, a 40 mg probiotic blend with 3.5 billion CFU and ‘Contains Milk.’ It should control over the sales page's B1-04 typo and ‘Dairy Free’ badge. Source: Official PurDentix commercial channel · Captured 2026-07-17. Highlight added by OralRadar. Affiliate link. If you buy, we may earn a commission at no extra cost to you. How this works.

The offer page displays FDA-facility, cGMP, non-GMO and allergen badges, but it gives no facility name, registration number, audit certificate or public certifier record. Those are vendor statements, not independently verified certifications. FDA says registration does not mean the agency approved the facility or product. I checked that distinction against the FDA’s approval guidance on July 16, 2026.

Highlighted FDA guidance explaining that dietary supplements are not approved for safety and effectiveness before sale Save
Official guidance FDA distinguishes dietary supplements from products that receive premarket approval for safety and effectiveness. Source: FDA 101: Dietary Supplements · Captured 2026-07-16. Highlight added by OralRadar.

Two honest cautions come straight off the ingredient panel. It is sweetened with sucralose, and it Contains Milk, a dairy allergen. Neither is a dealbreaker for most people, but if you have a milk allergy or avoid that sweetener, this isn’t your bottle.

The strains and prebiotic, and what the evidence really says

This is the part the sales page skips, so I want to be careful and specific. The rule that governs everything here: evidence belongs to an exact strain, not to a species name. A generic “L. reuteri” on a label is not automatically the “L. reuteri” tested in a trial. PurDentix identifies B. lactis BL-04, but its L. reuteri, L. paracasei and L. salivarius lack exact strain codes. BL-04 is not the HN019 gum-study strain, so none of the strongest cited results can be assumed to transfer to the finished formula.

First, the mechanism, so the idea isn’t hand-waving. Your mouth runs on a balanced community of microbes, and dental disease is largely a dysbiosis, a tilt in that balance toward acid-making or inflammation-driving bugs. Reviews of oral ecology describe how helpful species can buffer acid and crowd out troublemakers, which is the plausible reason an oral probiotic might help at all (According to PubMed, PMID 29195050, DOI; PMID 32307660, DOI). Plausible is not the same as proven, so here is strain by strain.

L. reuteri (best-supported, and only as an add-on). The reuteri combination studied for gums is a named pair, DSM 17938 plus ATCC PTA 5289. Used as an adjunct (an add-on) to a dentist’s deep cleaning, called scaling and root planing, it produced modest extra improvements in gum-pocket depth and attachment in randomized trials, though the meta-analysis authors call the benefit short-term (PMID 32373987, DOI; trials PMID 24164569 and PMID 25741580). Two honest limits: taken on its own for mild gingivitis, a systematic review found no significant difference versus placebo (PMID 31682012, DOI), and in smokers one trial found no benefit either (PMID 30931588, DOI). And again, PurDentix does not print the strain code, so a match to that studied pair is not guaranteed.

Screenshot of the PubMed study page for PMID 32373987 showing the Lactobacillus reuteri periodontitis meta-analysis title, authors, PMID and DOI Save
PubMed study page L. reuteri showed a short-term adjunctive benefit with scaling and root planing, not a replacement for it. Sources: PubMed PMID 32373987, DOI 10.26355/eurrev_202004_21032 · Captured 2026-07-17.

L. paracasei (moderate, but the strain has to match). The paracasei evidence in the mouth is for specific strains, Lpc-37 and SD1, mostly for reducing cavity-causing bacteria in children, and even there the certainty is graded moderate to low (PMID 41706206, DOI). A generic “L. paracasei” is not those strains, so this is promising for the species, unproven for this bottle.

B. lactis BL-04 (thin for the mouth). This one is a common mislead. The solid gum trial for a B. lactis used strain HN019 as an add-on to deep cleaning (PMID 30076613, DOI). PurDentix lists BL-04, a different strain that is studied mostly for immune and respiratory support, not periodontal health. BL-04’s oral evidence is essentially absent, and it should not borrow HN019’s results.

L. salivarius (limited, and not the famous one). Read this carefully. PurDentix uses Lactobacillus salivarius. The bacterium with the well-known bad-breath data is Streptococcus salivarius (the BLIS K12 and M18 strains). They are different genera, and the K12 breath evidence does not transfer to the Lactobacillus on this label. On its own, this ingredient’s oral evidence is limited.

Inulin (weak). The 100 mg of prebiotic fiber has a plausible feed-the-good-bugs rationale, but no trial has tested inulin alone for an oral outcome. A systematic review of prebiotic fibers and cavities was mostly test-tube work with few showing a pH benefit (PMID 39812321, DOI), and, tellingly, one children’s cavity trial used a large dose of inulin as its inert placebo (PMID 25428785, DOI).

Put together: the honest read is moderate at best, strain-specific, and adjunct-only. The strongest signals need the exact studied strains and a dentist’s cleaning underneath them. None of this cures gum disease, regrows gum tissue, or replaces professional care. If your gums bleed or hurt, see a dentist or periodontist first; a probiotic is at most a studied helper on top of that, and you can see how I weigh these things on the how we test page.

What the available user evidence can tell us

For real-world category context, I reviewed public retailer feedback for BioGaia Prodentis and NOW OralBiotic. They are different products with different strains, doses, formulations, mouth-contact time and use schedules. This is a qualitative synthesis of analogous products, not a statistical estimate or evidence for PurDentix itself.

Recurring themes include perceived fresher breath, oral comfort, pleasant taste and a routine that is easy to follow. The reports are not uniform: some people notice no clear or immediate effect, while others criticize taste, price or packaging. That mixed pattern is useful for understanding the category, but it cannot establish PurDentix’s benefits, onset or adverse-event frequency.

Complaints and negatives

Let me separate the fair criticisms from the noise, because both exist.

Fair, and worth knowing. The tablet was slow to dissolve and left a slightly chalky finish in the limited use notes. It contains sucralose and milk. BL-04 is identified, but the other three probiotic species lack exact strain codes, and the blend hides every per-species dose. The verified 60-day return window gives you a cutoff, but it does not prove that the formula works or remove the time and return-shipping cost of a trial.

Mostly noise. A newly launched, heavily advertised brand collects skeptical chatter fast, and PurDentix is no exception. Much of the “is this real?” worry online traces back to third-party Amazon listings rather than the product itself (see the channel section below). The core product isn’t the problem there; the reseller channel is.

Is PurDentix a scam?

Short answer: no, it is not a phantom checkout. The official page uses ClickBank checkout and states a 60-day money-back guarantee. That offer fact was checked on July 16, 2026; it isn’t a prediction about delivery quality or automatic refund approval.

The fair criticism isn’t fraud, it is overselling. The marketing implies more certainty than the evidence supports for a formula whose real-world proof is moderate at best and strain-dependent. Buy it understanding that, set modest expectations, and use the official channel so the guarantee and support actually apply to you.

PurDentix versus ProDentim: which one?

Because the formulas are twins, this is a short decision, not a long debate. On the bacteria and prebiotic, they are the same, so there is no “better formula” to chase.

Compare PurDentix and ProDentim on their currently disclosed labels, checkout prices and return terms; this review did not document evidence sufficient to rank one by brand history or manufacturing quality. Both currently state a 60-day return window, and I found no public certificate that gives PurDentix an independent quality advantage. The ProDentim review and best oral probiotics roundup lay out the remaining evidence gaps.

The honest verdict

PurDentix keeps its calibrated 6.8 out of 10. Its disclosed label mirrors ProDentim, but the strongest cited evidence belongs to exact strains that this formula either does not contain (HN019) or does not identify. The limited 21-day notes recorded a cleaner-feeling mouth and fresher morning breath, nothing dramatic, and no change in one gum spot; those observations are not clinical proof.

Who it’s for: someone who wants a low-effort, once-a-day oral probiotic and accepts that any benefit may be small or absent. The 60-day return window limits the purchase period; it does not make the trial risk-free.

Expectation boundary: whitening teeth, curing gum disease and replacing a dental visit are outside the evidence, and the formula has no finished-product trial. Its qualified-yes role is an optional adjunct on top of the basics, with professional cleanings kept in place.

Check the official PurDentix offer

Affiliate link. We may earn a commission at no cost to you. How this works.

Frequently asked questions

Is PurDentix safe, and does it have side effects?

The cited periodontal trials provide safety observations for their exact L. reuteri preparations, not this finished formula (PMID 24164569; PMID 25741580). PurDentix identifies BL-04 but not the exact L. reuteri, L. paracasei or L. salivarius strains, and it hides per-species amounts. The label Contains Milk (a dairy allergen) and uses sucralose. If you are pregnant, immunocompromised, take medication or have a milk allergy, review the label with a clinician first. Treat this as label reading and evidence review, not individual medical clearance.

Is PurDentix FDA approved?

No, and neither is any dietary supplement. The FDA does not approve supplements for safety or effectiveness before sale. The vendor page displays FDA-facility and cGMP badges, but I found no public certificate number or named certifier to verify them. Treat those as vendor manufacturing claims, not FDA approval or independent proof.

How long does PurDentix take to work?

No published trial of the finished PurDentix formula defines an onset. The cited probiotic studies measured outcomes over weeks, but they used exact strains and clinical contexts that do not match this label, so they cannot promise a one-to-two-week result. Treat it as an optional add-on to brushing and flossing, not a replacement.

Does PurDentix really work?

The finished formula has no published clinical trial. The cited results come from exact studied strains and clinical contexts such as the L. reuteri DSM 17938 plus ATCC PTA 5289 pair used alongside professional care (PMID 32373987; PMID 41706206). PurDentix identifies BL-04, which is not the HN019 gum-study strain, while its other probiotic species lack exact strain codes. Those studies therefore cannot establish that this bottle works; do not treat it as whitening or a cure.

Does PurDentix whiten teeth?

No. There is no evidence that an oral probiotic whitens teeth, that isn’t what these strains do, and PurDentix contains no whitening agent. Any “brighter smile” impression is likely just a cleaner-feeling mouth, not an actual shade change. For whitening, that is a conversation with your dentist.

Is PurDentix legit or a scam?

It is sold through a live ClickBank checkout with a 60-day vendor guarantee, checked July 16, 2026, and its label is near-identical to the better-known ProDentim. The honest catch isn’t the checkout; it is marketing that oversells a formula whose evidence is moderate at best. Buy through the official channel if you want the stated return terms and vendor support.

What are people saying on Reddit, Trustpilot and in complaints?

I did not use a dated, attributable Reddit, Trustpilot or BBB dataset for this review, so I cannot characterize overall sentiment or call any complaint recurring. Product-specific user sentiment remains unscored. If you buy, save the 60-day terms shown at checkout and document any support exchange.

Where can I buy PurDentix, and is it on Amazon or Walmart?

Third-party listings do appear on Amazon and Walmart, but those are reseller SKUs that may differ from the official formula. The vendor’s 60-day terms and support apply to the official channel, not automatically to a marketplace reseller.

Offer, certification and safety sources

I checked the official PurDentix offer (affiliate link; we may earn a commission at no extra cost to you), the ClickBank return policy, and the FDA explanation of supplement approval on July 16, 2026. The offer states 60 days, not 180. No NSF record or certificate number was provided on the offer, so this review makes no NSF-certified claim.

Highlighted ClickBank return-policy excerpt showing its standard 60-day window and seller-policy exception, used as context for PurDentix Save
Platform policy context ClickBank describes a standard 60-day window, matching PurDentix's stated guarantee. The "180-day" wording on the six-bottle pack describes supply duration, not the return period; the live product terms still govern a claim. Source: ClickBank Return and Subscription Cancellation Policy · Captured 2026-07-16. Highlight added by OralRadar.

What's inside vs the evidence

IngredientAmountWhat it's forHonest evidence read
Inulin (chicory root)100 mgPrebiotic fiber, meant to feed helpful mouth bacteriaWeak. No trial has tested inulin alone on teeth or gums, and one cavity study used 20 g of it as the inert placebo.
Lactobacillus reuteriin 40 mg blendGum-inflammation probioticModerate but strain-specific. The gum trials used the DSM 17938 plus ATCC PTA 5289 combo; this label prints no strain code.
Lactobacillus paracaseiin 40 mg blendAnti-cavity probioticModerate but strain-specific. The cavity evidence is for Lpc-37 and SD1 in children, not a generic paracasei.
Bifidobacterium lactis BL-04in 40 mg blendImmune-oriented probioticThin for the mouth. The gum RCT used a different strain (HN019); BL-04 is studied mostly for immunity.
Lactobacillus salivariusin 40 mg blendOral probioticLimited. This is Lactobacillus salivarius, not the S. salivarius K12 or M18 used in bad-breath studies, so that evidence does not carry over.

Pros & cons

Pros

  • One chewable a day, easy to keep up
  • Mouth felt cleaner and morning breath was fresher by week two in my short run
  • The official offer states a 60-day money-back guarantee
  • No side effects for me; named L. reuteri preparations were generally well tolerated in the cited trials

Cons

  • The tablet is slow to dissolve and leaves a faint chalky finish
  • Sweetened with sucralose and it contains milk, a dairy allergen
  • BL-04 is named, but L. reuteri, L. paracasei and L. salivarius lack exact strain codes; per-species doses are hidden
  • 3.5 billion CFU is modest, and a stubborn gum spot of mine never changed
  • Its disclosed label is a near-mirror of ProDentim; that similarity does not establish the same manufacturer, quality or performance

Official channel vs Amazon & eBay resellers

Official channel: The official channel sells the formula described here and states a 60-day money-back guarantee. Offer and refund terms were checked on July 16, 2026.

Amazon or eBay (3rd-party resellers): The Amazon and Walmart listings are third-party reseller SKUs, and buyers on the listing itself question whether they match the official product. The formula, packaging and guarantee can differ, so I can't vouch that it's the same bottle. eBay and other marketplace resellers carry the same risk: a different seller, possibly a different formula, and none of the maker's refund guarantee.

The offer & the catches

Format30 chewable tablets, one a day
PriceA live PurDentix price was not documented in the sources used for this review; verify the amount and pack size at checkout
Guarantee60 days, stated twice on the official offer page and checked July 16, 2026
CertificationThe vendor displays FDA-facility and cGMP badges but no public certificate number; treat these as vendor claims, not independent certification
Refund termsThe vendor says to return all bottles; ClickBank says physical-product returns follow the seller policy, so save the checkout terms

Where to buy & price

Buy through the official channel for the tested formula and the money-back guarantee.

See the official offer

Affiliate link. We may earn a commission at no cost to you. How this works.

References

  • U.S. Food and Drug Administration. Is It Really ‘FDA Approved’? [Internet]. FDA. Updated May 4, 2026; accessed July 17, 2026. Available from: FDA — Is It Really ‘FDA Approved’?

  • ClickBank. ClickBank’s Return and Subscription Cancellation Policy [Internet; return and subscription cancellation policy]. Published April 10, 2025; accessed July 17, 2026. Available from: ClickBank Return and Subscription Cancellation Policy

  • U.S. Food and Drug Administration. FDA 101: Dietary Supplements [Internet]. FDA. Content current as of June 2, 2022; accessed July 17, 2026. Available from: FDA 101 — Dietary Supplements

  • Rosier BT, Marsh PD, Mira A. Resilience of the Oral Microbiota in Health: Mechanisms That Prevent Dysbiosis. J Dent Res. 2018 Apr;97(4):371-380. https://doi.org/10.1177/0022034517742139 · PubMed PMID 29195050

  • Sivamaruthi BS, Kesika P, Chaiyasut C. A Review of the Role of Probiotic Supplementation in Dental Caries. Probiotics Antimicrob Proteins. 2020 Dec;12(4):1300-1309. https://doi.org/10.1007/s12602-020-09652-9 · PubMed PMID 32307660

  • Song D, Liu XR. Role of probiotics containing Lactobacillus reuteri in adjunct to scaling and root planing for management of patients with chronic periodontitis: a meta-analysis. Eur Rev Med Pharmacol Sci. 2020 Apr;24(8):4495-4505. https://doi.org/10.26355/eurrev_202004_21032 · PubMed PMID 32373987

  • Teughels W, Durukan A, Ozcelik O, Pauwels M, Quirynen M, Haytac MC. Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study. J Clin Periodontol. 2013 Nov;40(11):1025-35. https://doi.org/10.1111/jcpe.12155 · PubMed PMID 24164569

  • İnce G, Gürsoy H, İpçi ŞD, Cakar G, Emekli-Alturfan E, Yılmaz S. Clinical and Biochemical Evaluation of Lozenges Containing Lactobacillus reuteri as an Adjunct to Non-Surgical Periodontal Therapy in Chronic Periodontitis. J Periodontol. 2015 Jun;86(6):746-54. https://doi.org/10.1902/jop.2015.140612 · PubMed PMID 25741580

  • Akram Z, Shafqat SS, Aati S, Kujan O, Fawzy A. Clinical efficacy of probiotics in the treatment of gingivitis: A systematic review and meta-analysis. Aust Dent J. 2020 Mar;65(1):12-20. https://doi.org/10.1111/adj.12733 · PubMed PMID 31682012

  • Theodoro LH, Cláudio MM, Nuernberg MAA, Miessi DMJ, Batista JA, Duque C, et al. Effects of Lactobacillus reuteri as an adjunct to the treatment of periodontitis in smokers: randomised clinical trial. Benef Microbes. 2019 Apr 19;10(4):375-384. https://doi.org/10.3920/BM2018.0150 · PubMed PMID 30931588

  • Invernici MM, Salvador SL, Silva PHF, Soares MSM, Casarin R, Palioto DB, et al. Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial. J Clin Periodontol. 2018 Oct;45(10):1198-1210. https://doi.org/10.1111/jcpe.12995 · PubMed PMID 30076613

  • Rodriguez G, Fernández Godoy E, Chaple Gil A, Contador R, Bersezio Miranda C, Cabello R. Probiotic supplementation and dental caries prevention in children and adolescents: a systematic review of strain-specific and context-dependent effects. Clin Oral Investig. 2026 Feb 18;30(2):82. https://doi.org/10.1007/s00784-026-06752-8 · PubMed PMID 41706206

  • Fernández CE, Maturana-Valenzuela C, Rojas-Castillo N, Rosier B. Potential effects of prebiotic fibers on dental caries: a systematic review. J Sci Food Agric. 2025 Aug 30;105(11):5640-5651. https://doi.org/10.1002/jsfa.14113 · PubMed PMID 39812321

  • Lee W, Spiekerman C, Heima M, Eggertsson H, Ferretti G, Milgrom P, et al. The effectiveness of xylitol in a school-based cluster-randomized clinical trial. Caries Res. 2015;49(1):41-9. https://doi.org/10.1159/000360869 · PubMed PMID 25428785

Who's behind this

Eduardo Silva

Eduardo Silva · Founder & Product Tester

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