Introduction

This dataset contains nine tissues (heart, hippocampus, hypothalamus, kidney, liver, prefrontal cortex, skeletal muscle, small intestine, and spleen) from C57BL/6J mice that were fed 2-deoxyglucose (6g/L) through their drinking water for 96hrs or 4wks. 96hr mice were given their 2DG treatment 2 weeks after the other cohort started the 4 week treatment. The organs from the mice were harvested and processed for metabolomics and transcriptomics. The data in this document pertains to the transcriptomics data only. The counts that were used were FPKM normalized before being log transformed. It was determined that sample A113 had low RNAseq quality and through further analyses with PCA, MA plots, and clustering was an outlier and will be removed for the rest of the analyses performed. This document will the significance of the main effects and their interaction for each gene in each module.

needed.packages <- c("tidyverse", "here", "functional", "gplots", "dplyr", "GeneOverlap", "R.utils", "reshape2","magrittr","data.table", "RColorBrewer","preprocessCore", "ARTool","emmeans", "phia", "gprofiler2","rlist", "plotly","kableExtra","foreach","doParallel","doFuture","downloadthis")
for(i in 1:length(needed.packages)){library(needed.packages[i], character.only = TRUE)}

source(here("source_files","WGCNA_source.R"))
WGCNA.pathway <-readRDS(here("Data","Chang_B6_96hr_4wk_gprofiler_pathway_annotation_list_WGCNA.RData"))

WGCNA.gene <-readRDS(here("Data","Chang_B6_96hr_4wk_gprofiler_gene_annotation_list_WGCNA.RData"))

tdata.FPKM.sample.info <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_phenotypes.RData"))

tdata.FPKM <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_numeric.RData"))

log.tdata.FPKM <- log(tdata.FPKM + 1)
log.tdata.FPKM <- as.data.frame(log.tdata.FPKM)

log.tdata.FPKM.sample.info <- cbind(log.tdata.FPKM, tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()

log.tdata.FPKM.subset <- log.tdata.FPKM[,colMeans(log.tdata.FPKM != 0) > 0.5] 

log.tdata.FPKM.sample.info.subset <- cbind(log.tdata.FPKM.subset,tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()


ensembl.location <- readRDS(here("Data","Ensembl_gene_id_and_location.RData"))

Matched<-readRDS(here("Data","Annotated_genes_in_WGCNA_Chang_B6_96hr_4wk.RData"))


module.names <- Matched$X..Module.
name <- str_split(module.names,"_")
samples <-c()
for(i in 1:length(name)){
samples[[i]] <- name[[i]][2]
}  
name2 <- stringr::str_split(samples,"\"")
mod.names <- c()
for(i in 1:length(name2)){
   mod.names[[i]] <- name2[[i]][1]
}
name2 <- unlist(mod.names)
modules <- unique(mod.names)
modules <- unlist(modules)

ANOVA

log.tdata.FPKM.sample.info.subset$Time <- as.factor(log.tdata.FPKM.sample.info.subset$Time)
log.tdata.FPKM.sample.info.subset$Treatment <- as.factor(log.tdata.FPKM.sample.info.subset$Treatment)

ANOVA.gene.pathways(WGCNA.gene, log.tdata.FPKM.sample.info.subset)

black

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hk2 ENSMUSG00000000628 0.529886281855088 0.794829422782632 0.474398949479646 0.794829422782632 0.877649489117496 0.877649489117496
Cyp51 ENSMUSG00000001467 0.452871858403942 0.946504904590542 0.946504904590542 0.946504904590542 0.883893324660543 0.946504904590542
Akr1b3 ENSMUSG00000001642 0.661226232427195 0.840468164906683 0.834307586653806 0.840468164906683 0.840468164906683 0.840468164906683
Gmpr2 ENSMUSG00000002326 0.824803497127901 0.952772392121483 0.521710971213641 0.952772392121483 0.952772392121483 0.952772392121483
Uck1 ENSMUSG00000002550 0.0522085744936216 0.156625723480865 0.108651693385251 0.162977540077876 0.743154017466363 0.743154017466363
Gys1 ENSMUSG00000003865 0.320759848146992 0.878161215149676 0.585440810099784 0.878161215149676 0.908415934661294 0.908415934661294
Nmrk2 ENSMUSG00000004939 0.572018737852217 0.856162455374755 0.856162455374755 0.856162455374755 0.744357137979439 0.856162455374755
Kdsr ENSMUSG00000009905 0.837331189823357 0.908851229989699 0.779264341265078 0.908851229989699 0.908851229989699 0.908851229989699
Pdhx ENSMUSG00000010914 0.135861871252294 0.407585613756883 0.72535165739096 0.72535165739096 0.707162361637502 0.72535165739096
Adssl1 ENSMUSG00000011148 0.719403049551864 0.791411383340349 0.512073095716585 0.791411383340349 0.791411383340349 0.791411383340349
Cers2 ENSMUSG00000015714 0.818921741891611 0.818921741891611 0.424802369954417 0.818921741891611 0.572310073972002 0.818921741891611
Adss ENSMUSG00000015961 0.397242735800211 0.887013357001742 0.837225068436136 0.887013357001742 0.887013357001742 0.887013357001742
Pnpo ENSMUSG00000018659 0.602169148837665 0.658369671645338 0.0212933523579156 0.0638800570737468 0.658369671645338 0.658369671645338
Mdh2 ENSMUSG00000019179 0.41721098230089 0.582674757551257 0.103158903079635 0.309476709238906 0.582674757551257 0.582674757551257
Gyg ENSMUSG00000019528 0.849666614754592 0.977948989520894 0.588546522338463 0.977948989520894 0.977948989520894 0.977948989520894
Pgam2 ENSMUSG00000020475 0.803488081744024 0.918260884175039 0.918260884175039 0.918260884175039 0.754962171678621 0.918260884175039
Nampt ENSMUSG00000020572 0.152696678403342 0.229045017605013 0.0464409495213126 0.139322848563938 0.834308571256967 0.834308571256967
Galk1 ENSMUSG00000020766 0.0902796195981084 0.25013503406605 0.166756689377367 0.25013503406605 0.959067447272555 0.959067447272555
Ckmt2 ENSMUSG00000021622 0.32358686358372 0.485380295375579 0.538285521957261 0.538285521957261 0.0883697866914702 0.26510936007441
Glud1 ENSMUSG00000021794 0.320952436230156 0.481428654345234 0.202467520870727 0.481428654345234 0.837354324155961 0.837354324155961
Galnt15 ENSMUSG00000021903 0.102657144892883 0.30797143467865 0.955897406440096 0.955897406440096 0.222807117345465 0.334210676018198
Tkt ENSMUSG00000021957 0.45527552508508 0.558933957546336 0.144887081286411 0.434661243859232 0.558933957546336 0.558933957546336
Adsl ENSMUSG00000022407 0.431654439681658 0.431654439681658 0.313309459731996 0.431654439681658 0.307600177772793 0.431654439681658
St3gal6 ENSMUSG00000022747 0.276690245797794 0.830070737393381 0.98740557010903 0.98740557010903 0.840417381084446 0.98740557010903
Pigp ENSMUSG00000022940 0.346399377306308 0.987398851502297 0.862050815571285 0.987398851502297 0.987398851502297 0.987398851502297
Acat2 ENSMUSG00000023832 0.641224152175957 0.641224152175957 0.632808282266189 0.641224152175957 0.610443987035996 0.641224152175957
Lpin2 ENSMUSG00000024052 0.176867536939679 0.530602610819038 0.501820618267796 0.698720663244666 0.698720663244666 0.698720663244666
2410127L17Rik ENSMUSG00000024726 0.241558422172384 0.724675266517151 0.962229061152698 0.962229061152698 0.859031394789368 0.962229061152698
Tm7sf2 ENSMUSG00000024799 0.404412974565039 0.630341017643403 0.420227345095602 0.630341017643403 0.782327082059754 0.782327082059754
Chka ENSMUSG00000024843 0.962222460920168 0.962222460920168 0.415654799586714 0.962222460920168 0.812773962335868 0.962222460920168
Pcyt2 ENSMUSG00000025137 0.542765158884116 0.722377432997962 0.489150948371185 0.722377432997962 0.722377432997962 0.722377432997962
Cbr2 ENSMUSG00000025150 0.484318921331602 0.734172138849432 0.734172138849432 0.734172138849432 0.558887725409495 0.734172138849432
Cox8b ENSMUSG00000025488 0.977603411710332 0.977603411710332 0.939216033767479 0.977603411710332 0.648372670032277 0.977603411710332
Eprs ENSMUSG00000026615 0.0046226381968964 0.0138679145906892 0.0175051527410108 0.0262577291115162 0.825015331774026 0.825015331774026
Hsd17b12 ENSMUSG00000027195 0.524511747296257 0.853987326699762 0.569324884466508 0.853987326699762 0.874551848235739 0.874551848235739
Impa1 ENSMUSG00000027531 0.11641194927646 0.349235847829381 0.681387381293969 0.719410885492592 0.719410885492592 0.719410885492592
Slc33a1 ENSMUSG00000027822 0.902623958936428 0.908883647476402 0.501945465530588 0.908883647476402 0.908883647476402 0.908883647476402
Pla2g12a ENSMUSG00000027999 0.51915760936776 0.681110061974765 0.161590636592744 0.484771909778233 0.681110061974765 0.681110061974765
Txndc12 ENSMUSG00000028567 0.743105140154027 0.743105140154027 0.532275996984502 0.743105140154027 0.663942588704972 0.743105140154027
Gale ENSMUSG00000028671 0.224436476398306 0.673309429194918 0.529974837352315 0.695842752583996 0.695842752583996 0.695842752583996
Ddost ENSMUSG00000028757 0.272995291553747 0.344724887705498 0.0356395032378288 0.106918509713486 0.344724887705498 0.344724887705498
Aacs ENSMUSG00000029482 0.524774519824757 0.663968020166544 0.205321051401248 0.615963154203744 0.663968020166544 0.663968020166544
Rpn1 ENSMUSG00000030062 0.981104809235214 0.981104809235214 0.0753069904656986 0.225920971397096 0.666941008989018 0.981104809235214
Ckm ENSMUSG00000030399 0.728000987997703 0.728000987997703 0.658355622640328 0.728000987997703 0.0193692900726574 0.0581078702179721
Aldoa ENSMUSG00000030695 0.556090616919459 0.593936090318536 0.171716582318927 0.51514974695678 0.593936090318536 0.593936090318536
Cox6a2 ENSMUSG00000030785 0.20675885058704 0.563983123097593 0.375988748731729 0.563983123097593 0.593997755842336 0.593997755842336
Nsdhl ENSMUSG00000031349 0.965370288821198 0.965370288821198 0.9088729501863 0.965370288821198 0.350924495069941 0.965370288821198
Sc4mol ENSMUSG00000031604 0.79118545377141 0.88701142705579 0.88701142705579 0.88701142705579 0.599043945326172 0.88701142705579
Elovl5 ENSMUSG00000032349 0.51138405733522 0.77596684904636 0.61554909480271 0.77596684904636 0.77596684904636 0.77596684904636
Gclc ENSMUSG00000032350 0.297438000210889 0.892314000632668 0.757950419416798 0.968442923961496 0.968442923961496 0.968442923961496
Pygm ENSMUSG00000032648 0.610224044569715 0.971648828007182 0.933933482542211 0.971648828007182 0.971648828007182 0.971648828007182
Agl ENSMUSG00000033400 0.824734183521311 0.824734183521311 0.652148465047518 0.824734183521311 0.695914018257903 0.824734183521311
Dhcr24 ENSMUSG00000034926 0.678509413589362 0.846639516345943 0.499383034503666 0.846639516345943 0.846639516345943 0.846639516345943
Ptplb ENSMUSG00000035376 0.912001829268531 0.912001829268531 0.472069795176298 0.912001829268531 0.812761769000692 0.912001829268531
Cox8a ENSMUSG00000035885 0.846324437313378 0.846324437313378 0.595919584036583 0.846324437313378 0.692998679565229 0.846324437313378
Acaa1a ENSMUSG00000036138 0.00444388996314033 0.013331669889421 0.0235946568497618 0.0353919852746427 0.655056305062266 0.655056305062266
9630033F20Rik ENSMUSG00000038028 0.661209054369198 0.859007167043476 0.859007167043476 0.859007167043476 0.8528374807788 0.859007167043476
B3galnt2 ENSMUSG00000039242 0.566583921194548 0.849875881791822 0.390868457926918 0.849875881791822 0.984254435801651 0.984254435801651
Ndufa4l2 ENSMUSG00000040280 0.458980983673614 0.688471475510421 0.3590714054268 0.688471475510421 0.908664964066354 0.908664964066354
Cox6a1 ENSMUSG00000041697 0.480538385862397 0.720807578793595 0.047417334601801 0.142252003805403 0.837123903085965 0.837123903085965
Coq5 ENSMUSG00000041733 0.867766421799548 0.867766421799548 0.107045326208503 0.321135978625508 0.625527544812513 0.867766421799548
Pla2g4e ENSMUSG00000050211 0.68495035176486 0.857200323203265 0.717966789808846 0.857200323203265 0.857200323203265 0.857200323203265
Phospho1 ENSMUSG00000050860 0.840474333736705 0.874558766547508 0.232122433644342 0.696367300933026 0.874558766547508 0.874558766547508
Smyd1 ENSMUSG00000055027 0.767192072358764 0.912007368136567 0.912007368136567 0.912007368136567 0.690074220713693 0.912007368136567
Gadl1 ENSMUSG00000056880 0.768699448329633 0.947107763629875 0.947107763629875 0.947107763629875 0.938879126265049 0.947107763629875
Sphk2 ENSMUSG00000057342 0.0784754843738117 0.235426453121435 0.382376140179715 0.501631208892123 0.501631208892123 0.501631208892123
Gapdh ENSMUSG00000057666 0.621432797553614 0.621432797553614 0.103743766779268 0.311231300337805 0.457546081189186 0.621432797553614
Idi1 ENSMUSG00000058258 0.604889279285322 0.666845975831665 0.408902348934052 0.666845975831665 0.666845975831665 0.666845975831665
Dhcr7 ENSMUSG00000058454 0.348688506314975 0.452682016275079 0.32103790115299 0.452682016275079 0.452682016275079 0.452682016275079
Eno3 ENSMUSG00000060600 0.346808518223055 0.952791600896597 0.952791600896597 0.952791600896597 0.825070111616799 0.952791600896597
Hsd3b2 ENSMUSG00000063730 0.921373793826898 0.921373793826898 0.517123804336849 0.921373793826898 0.852804183325862 0.921373793826898
Amd2 ENSMUSG00000063953 0.623546155165948 0.756262541776241 0.756262541776241 0.756262541776241 0.652425242803339 0.756262541776241
Rdh11 ENSMUSG00000066441 0.918204736055969 0.918204736055969 0.582806160590683 0.918204736055969 0.635668654799379 0.918204736055969
Ampd1 ENSMUSG00000070385 0.136058504045265 0.240611974830234 0.160407983220156 0.240611974830234 0.280065514247848 0.280065514247848
Ganab ENSMUSG00000071650 0.196813185463291 0.27676043506827 0.0857676110992905 0.257302833297871 0.27676043506827 0.27676043506827
Amd1 ENSMUSG00000075232 0.416709499248637 0.82809780731503 0.772650791388587 0.82809780731503 0.82809780731503 0.82809780731503

Protein processing in endoplasmic reticulum

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkcsh ENSMUSG00000003402 0.0953311218585688 0.142996682787853 0.00296935408367279 0.00890806225101837 0.739761042027988 0.739761042027988
Calr ENSMUSG00000003814 0.98110095931466 0.996846692422101 0.0341854236598362 0.102556270979509 0.996846692422101 0.996846692422101
Hspa1l ENSMUSG00000007033 0.993484908396619 0.993484908396619 0.358801495341612 0.993484908396619 0.716364835692103 0.993484908396619
Rnf5 ENSMUSG00000015478 0.818586902833238 0.818586902833238 0.713159110308385 0.818586902833238 0.675208172107592 0.818586902833238
Sec63 ENSMUSG00000019802 0.340379550727237 0.758137910591425 0.758137910591425 0.758137910591425 0.604622687362431 0.758137910591425
Hsp90b1 ENSMUSG00000020048 0.122086437925427 0.366259313776281 0.278215116821077 0.417322675231616 0.5857963255755 0.5857963255755
Canx ENSMUSG00000020368 0.0257571031258144 0.0772713093774433 0.408900146526408 0.613350219789612 0.713534532973954 0.713534532973954
Pdia6 ENSMUSG00000020571 0.168962812092708 0.342347317321312 0.228231544880875 0.342347317321312 0.791264464327207 0.791264464327207
Pdia3 ENSMUSG00000027248 0.871352656852258 0.896359796659511 0.629762238718294 0.896359796659511 0.896359796659511 0.896359796659511
Sec23b ENSMUSG00000027429 0.115519697244833 0.346559091734498 0.886996121840201 0.886996121840201 0.588496674538511 0.882745011807766
Dnaja1 ENSMUSG00000028410 0.000276381257016233 0.0008291437710487 0.149044475503546 0.22356671325532 0.556010786408006 0.556010786408006
Ddost ENSMUSG00000028757 0.272995291553747 0.344724887705498 0.0356395032378288 0.106918509713486 0.344724887705498 0.344724887705498
Rpn1 ENSMUSG00000030062 0.981104809235214 0.981104809235214 0.0753069904656986 0.225920971397096 0.666941008989018 0.981104809235214
Sec61a1 ENSMUSG00000030082 0.566810980461262 0.574948612328729 0.183364652509316 0.550093957527948 0.574948612328729 0.574948612328729
Hyou1 ENSMUSG00000032115 0.236291623755458 0.541523134994172 0.361015423329448 0.541523134994172 0.896249418695161 0.896249418695161
Os9 ENSMUSG00000040462 0.566190177069544 0.658185073540793 0.490733581154019 0.658185073540793 0.658185073540793 0.658185073540793
Ganab ENSMUSG00000071650 0.196813185463291 0.27676043506827 0.0857676110992905 0.257302833297871 0.27676043506827 0.27676043506827

Cardiac muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Trdn ENSMUSG00000019787 0.37674608175968 0.37674608175968 0.201630961065485 0.37674608175968 0.310748002384199 0.37674608175968
Cacng1 ENSMUSG00000020722 0.644423706162384 0.644423706162384 0.431193017999504 0.644423706162384 0.270966004300595 0.644423706162384
Cox8b ENSMUSG00000025488 0.977603411710332 0.977603411710332 0.939216033767479 0.977603411710332 0.648372670032277 0.977603411710332
Cacna1s ENSMUSG00000026407 0.532529237741279 0.798793856611918 0.524854583665002 0.798793856611918 0.843523002135889 0.843523002135889
Asph ENSMUSG00000028207 0.770229270760848 0.971667351531664 0.965374709072213 0.971667351531664 0.971667351531664 0.971667351531664
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Cox6a2 ENSMUSG00000030785 0.20675885058704 0.563983123097593 0.375988748731729 0.563983123097593 0.593997755842336 0.593997755842336
Tpm1 ENSMUSG00000032366 0.840457460024872 0.968520746487624 0.968520746487624 0.968520746487624 0.632829224190685 0.968520746487624
Cox8a ENSMUSG00000035885 0.846324437313378 0.846324437313378 0.595919584036583 0.846324437313378 0.692998679565229 0.846324437313378
Hrc ENSMUSG00000038239 0.958490981524188 0.958490981524188 0.457291286908005 0.958490981524188 0.840958095315758 0.958490981524188
Cox6a1 ENSMUSG00000041697 0.480538385862397 0.720807578793595 0.047417334601801 0.142252003805403 0.837123903085965 0.837123903085965
Cacng6 ENSMUSG00000078815 0.8134372209588 0.987244037432522 0.872910896977964 0.987244037432522 0.987244037432522 0.987244037432522

Arrhythmogenic right ventricular cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sgca ENSMUSG00000001508 0.729518947136317 0.729518947136317 0.72383760558477 0.729518947136317 0.546716798120882 0.729518947136317
Actn3 ENSMUSG00000006457 0.655230626830142 0.655230626830142 0.508349446776414 0.655230626830142 0.0648034225997438 0.194410267799231
Lama2 ENSMUSG00000019899 0.45701302497334 0.45701302497334 0.354172130793533 0.45701302497334 0.392871367150466 0.45701302497334
Sgcd ENSMUSG00000020354 0.635653024249237 0.734247431378973 0.734247431378973 0.734247431378973 0.675585234532873 0.734247431378973
Cacng1 ENSMUSG00000020722 0.644423706162384 0.644423706162384 0.431193017999504 0.644423706162384 0.270966004300595 0.644423706162384
Cacna1s ENSMUSG00000026407 0.532529237741279 0.798793856611918 0.524854583665002 0.798793856611918 0.843523002135889 0.843523002135889
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Sgcg ENSMUSG00000035296 0.275086368267256 0.825259104801768 0.883687196442191 0.9683076017927 0.9683076017927 0.9683076017927
Actn2 ENSMUSG00000052374 0.933704199733417 0.984198183387724 0.74004851085019 0.984198183387724 0.984198183387724 0.984198183387724
Ctnna3 ENSMUSG00000060843 0.631668912302217 0.671228827462014 0.671228827462014 0.671228827462014 0.62987480159693 0.671228827462014
Cacng6 ENSMUSG00000078815 0.8134372209588 0.987244037432522 0.872910896977964 0.987244037432522 0.987244037432522 0.987244037432522

Steroid biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp51 ENSMUSG00000001467 0.452871858403942 0.946504904590542 0.946504904590542 0.946504904590542 0.883893324660543 0.946504904590542
Tm7sf2 ENSMUSG00000024799 0.404412974565039 0.630341017643403 0.420227345095602 0.630341017643403 0.782327082059754 0.782327082059754
Nsdhl ENSMUSG00000031349 0.965370288821198 0.965370288821198 0.9088729501863 0.965370288821198 0.350924495069941 0.965370288821198
Sc4mol ENSMUSG00000031604 0.79118545377141 0.88701142705579 0.88701142705579 0.88701142705579 0.599043945326172 0.88701142705579
Dhcr24 ENSMUSG00000034926 0.678509413589362 0.846639516345943 0.499383034503666 0.846639516345943 0.846639516345943 0.846639516345943
Dhcr7 ENSMUSG00000058454 0.348688506314975 0.452682016275079 0.32103790115299 0.452682016275079 0.452682016275079 0.452682016275079

Hypertrophic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sgca ENSMUSG00000001508 0.729518947136317 0.729518947136317 0.72383760558477 0.729518947136317 0.546716798120882 0.729518947136317
Prkag3 ENSMUSG00000006542 0.796823311589213 0.964785784752668 0.964785784752668 0.964785784752668 0.901612617338151 0.964785784752668
Lama2 ENSMUSG00000019899 0.45701302497334 0.45701302497334 0.354172130793533 0.45701302497334 0.392871367150466 0.45701302497334
Sgcd ENSMUSG00000020354 0.635653024249237 0.734247431378973 0.734247431378973 0.734247431378973 0.675585234532873 0.734247431378973
Cacng1 ENSMUSG00000020722 0.644423706162384 0.644423706162384 0.431193017999504 0.644423706162384 0.270966004300595 0.644423706162384
Cacna1s ENSMUSG00000026407 0.532529237741279 0.798793856611918 0.524854583665002 0.798793856611918 0.843523002135889 0.843523002135889
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Tpm1 ENSMUSG00000032366 0.840457460024872 0.968520746487624 0.968520746487624 0.968520746487624 0.632829224190685 0.968520746487624
Sgcg ENSMUSG00000035296 0.275086368267256 0.825259104801768 0.883687196442191 0.9683076017927 0.9683076017927 0.9683076017927
Ttn ENSMUSG00000051747 0.50459520346277 0.879164917949511 0.75916415878315 0.879164917949511 0.879164917949511 0.879164917949511
Cacng6 ENSMUSG00000078815 0.8134372209588 0.987244037432522 0.872910896977964 0.987244037432522 0.987244037432522 0.987244037432522

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sgca ENSMUSG00000001508 0.729518947136317 0.729518947136317 0.72383760558477 0.729518947136317 0.546716798120882 0.729518947136317
Lama2 ENSMUSG00000019899 0.45701302497334 0.45701302497334 0.354172130793533 0.45701302497334 0.392871367150466 0.45701302497334
Sgcd ENSMUSG00000020354 0.635653024249237 0.734247431378973 0.734247431378973 0.734247431378973 0.675585234532873 0.734247431378973
Cacng1 ENSMUSG00000020722 0.644423706162384 0.644423706162384 0.431193017999504 0.644423706162384 0.270966004300595 0.644423706162384
Cacna1s ENSMUSG00000026407 0.532529237741279 0.798793856611918 0.524854583665002 0.798793856611918 0.843523002135889 0.843523002135889
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Tpm1 ENSMUSG00000032366 0.840457460024872 0.968520746487624 0.968520746487624 0.968520746487624 0.632829224190685 0.968520746487624
Sgcg ENSMUSG00000035296 0.275086368267256 0.825259104801768 0.883687196442191 0.9683076017927 0.9683076017927 0.9683076017927
Ttn ENSMUSG00000051747 0.50459520346277 0.879164917949511 0.75916415878315 0.879164917949511 0.879164917949511 0.879164917949511
Cacng6 ENSMUSG00000078815 0.8134372209588 0.987244037432522 0.872910896977964 0.987244037432522 0.987244037432522 0.987244037432522

Calcium signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
P2rx5 ENSMUSG00000005950 0.704567724489871 0.893213514787605 0.846655752126242 0.893213514787605 0.893213514787605 0.893213514787605
Casq1 ENSMUSG00000007122 0.594293472168487 0.780910934337983 0.749028663356148 0.780910934337983 0.780910934337983 0.780910934337983
Vdac3 ENSMUSG00000008892 0.764161721891523 0.927667902022012 0.338733928160766 0.927667902022012 0.927667902022012 0.927667902022012
Tnnc2 ENSMUSG00000017300 0.924497078725 0.924497078725 0.550882366592979 0.826323549889469 0.0234038837911504 0.0702116513734513
Trdn ENSMUSG00000019787 0.37674608175968 0.37674608175968 0.201630961065485 0.37674608175968 0.310748002384199 0.37674608175968
P2rx6 ENSMUSG00000022758 0.305643022346267 0.652454994678328 0.652454994678328 0.652454994678328 0.506925920766824 0.652454994678328
Cacna1s ENSMUSG00000026407 0.532529237741279 0.798793856611918 0.524854583665002 0.798793856611918 0.843523002135889 0.843523002135889
Mylk2 ENSMUSG00000027470 0.827930595148742 0.827930595148742 0.608849326395783 0.827930595148742 0.766073256686237 0.827930595148742
Asph ENSMUSG00000028207 0.770229270760848 0.971667351531664 0.965374709072213 0.971667351531664 0.971667351531664 0.971667351531664
Hgf ENSMUSG00000028864 0.192589313784349 0.288883970676523 0.0806825684579269 0.242047705373781 0.868321974002268 0.868321974002268
Ryr1 ENSMUSG00000030592 0.948808918511902 0.987192249961937 0.987192249961937 0.987192249961937 0.660867223015917 0.987192249961937
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Phka1 ENSMUSG00000034055 0.984231708943008 0.984231708943008 0.782006240715006 0.984231708943008 0.921401548089613 0.984231708943008
Phkb ENSMUSG00000036879 0.799737795285277 0.799737795285277 0.306014925932717 0.799737795285277 0.649657393068437 0.799737795285277
Hrc ENSMUSG00000038239 0.958490981524188 0.958490981524188 0.457291286908005 0.958490981524188 0.840958095315758 0.958490981524188
Mylk4 ENSMUSG00000044951 0.61565873113832 0.92348809670748 0.937257730981507 0.937257730981507 0.548901985498534 0.92348809670748
Sphk2 ENSMUSG00000057342 0.0784754843738117 0.235426453121435 0.382376140179715 0.501631208892123 0.501631208892123 0.501631208892123

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gys1 ENSMUSG00000003865 0.320759848146992 0.878161215149676 0.585440810099784 0.878161215149676 0.908415934661294 0.908415934661294
Ctsd ENSMUSG00000007891 0.580375350914301 0.883895628989744 0.707649275618957 0.883895628989744 0.883895628989744 0.883895628989744
Vdac3 ENSMUSG00000008892 0.764161721891523 0.927667902022012 0.338733928160766 0.927667902022012 0.927667902022012 0.927667902022012
Slc2a4 ENSMUSG00000018566 0.871322383094052 0.959034159496675 0.384630797251266 0.959034159496675 0.959034159496675 0.959034159496675
Pdk4 ENSMUSG00000019577 0.0595773168494446 0.0893659752741668 0.0105006607442286 0.0315019822326859 0.42329958285333 0.42329958285333
Mapk12 ENSMUSG00000022610 0.477069802865994 0.943367184017789 0.943367184017789 0.943367184017789 0.734249687739066 0.943367184017789
Cox8b ENSMUSG00000025488 0.977603411710332 0.977603411710332 0.939216033767479 0.977603411710332 0.648372670032277 0.977603411710332
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Cox6a2 ENSMUSG00000030785 0.20675885058704 0.563983123097593 0.375988748731729 0.563983123097593 0.593997755842336 0.593997755842336
Cox8a ENSMUSG00000035885 0.846324437313378 0.846324437313378 0.595919584036583 0.846324437313378 0.692998679565229 0.846324437313378
Ndufa4l2 ENSMUSG00000040280 0.458980983673614 0.688471475510421 0.3590714054268 0.688471475510421 0.908664964066354 0.908664964066354
Cox6a1 ENSMUSG00000041697 0.480538385862397 0.720807578793595 0.047417334601801 0.142252003805403 0.837123903085965 0.837123903085965
Gapdh ENSMUSG00000057666 0.621432797553614 0.621432797553614 0.103743766779268 0.311231300337805 0.457546081189186 0.621432797553614
Mcpt4 ENSMUSG00000061068 0.238820136063233 0.716460408189699 0.644057857017589 0.828270587474474 0.828270587474474 0.828270587474474
Cpt1b ENSMUSG00000078937 0.321898818334591 0.779140322933077 0.779140322933077 0.779140322933077 0.62895029801752 0.779140322933077

Striated Muscle Contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tmod4 ENSMUSG00000005628 0.877665282121148 0.877665282121148 0.501757393862753 0.877665282121148 0.641229372401793 0.877665282121148
Actn3 ENSMUSG00000006457 0.655230626830142 0.655230626830142 0.508349446776414 0.655230626830142 0.0648034225997438 0.194410267799231
Tcap ENSMUSG00000007877 0.529757272056652 0.794635908084979 0.91818951809127 0.91818951809127 0.469474284048926 0.794635908084979
Tnnc2 ENSMUSG00000017300 0.924497078725 0.924497078725 0.550882366592979 0.826323549889469 0.0234038837911504 0.0702116513734513
Mybpc1 ENSMUSG00000020061 0.809446774270239 0.809446774270239 0.491496923279336 0.809446774270239 0.793754424786922 0.809446774270239
Neb ENSMUSG00000026950 0.0835414698562172 0.133099788316306 0.0887331922108705 0.133099788316306 0.661108844381704 0.661108844381704
Tnni2 ENSMUSG00000031097 0.303271288898002 0.447061316840291 0.447061316840291 0.447061316840291 0.139121062870999 0.417363188612996
Acta1 ENSMUSG00000031972 0.660661363813842 0.828136327451542 0.828136327451542 0.828136327451542 0.362627448818893 0.828136327451542
Tpm1 ENSMUSG00000032366 0.840457460024872 0.968520746487624 0.968520746487624 0.968520746487624 0.632829224190685 0.968520746487624
Mybpc2 ENSMUSG00000038670 0.754208274196812 0.811109265590511 0.811109265590511 0.811109265590511 0.229908965945837 0.689726897837512
Ttn ENSMUSG00000051747 0.50459520346277 0.879164917949511 0.75916415878315 0.879164917949511 0.879164917949511 0.879164917949511
Actn2 ENSMUSG00000052374 0.933704199733417 0.984198183387724 0.74004851085019 0.984198183387724 0.984198183387724 0.984198183387724
Myl1 ENSMUSG00000061816 0.531626463825679 0.612375956725726 0.612375956725726 0.612375956725726 0.032604052802775 0.0978121584083249
Tnnt1 ENSMUSG00000064179 0.917834344074881 0.917834344074881 0.564518989098426 0.917834344074881 0.698132123334534 0.917834344074881

Muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tmod4 ENSMUSG00000005628 0.877665282121148 0.877665282121148 0.501757393862753 0.877665282121148 0.641229372401793 0.877665282121148
Actn3 ENSMUSG00000006457 0.655230626830142 0.655230626830142 0.508349446776414 0.655230626830142 0.0648034225997438 0.194410267799231
Casq1 ENSMUSG00000007122 0.594293472168487 0.780910934337983 0.749028663356148 0.780910934337983 0.780910934337983 0.780910934337983
Tcap ENSMUSG00000007877 0.529757272056652 0.794635908084979 0.91818951809127 0.91818951809127 0.469474284048926 0.794635908084979
Tnnc2 ENSMUSG00000017300 0.924497078725 0.924497078725 0.550882366592979 0.826323549889469 0.0234038837911504 0.0702116513734513
Trdn ENSMUSG00000019787 0.37674608175968 0.37674608175968 0.201630961065485 0.37674608175968 0.310748002384199 0.37674608175968
Mybpc1 ENSMUSG00000020061 0.809446774270239 0.809446774270239 0.491496923279336 0.809446774270239 0.793754424786922 0.809446774270239
Neb ENSMUSG00000026950 0.0835414698562172 0.133099788316306 0.0887331922108705 0.133099788316306 0.661108844381704 0.661108844381704
Asph ENSMUSG00000028207 0.770229270760848 0.971667351531664 0.965374709072213 0.971667351531664 0.971667351531664 0.971667351531664
Abcc9 ENSMUSG00000030249 0.949601957584526 0.949601957584526 0.285510612756224 0.856531838268671 0.797346102243198 0.949601957584526
Ryr1 ENSMUSG00000030592 0.948808918511902 0.987192249961937 0.987192249961937 0.987192249961937 0.660867223015917 0.987192249961937
Mylpf ENSMUSG00000030672 0.818933306408874 0.834264337970699 0.664043434109457 0.834264337970699 0.834264337970699 0.834264337970699
Atp2a1 ENSMUSG00000030730 0.987392556519111 0.987392556519111 0.35043699836488 0.52565549754732 0.0413842558944132 0.12415276768324
Tnni2 ENSMUSG00000031097 0.303271288898002 0.447061316840291 0.447061316840291 0.447061316840291 0.139121062870999 0.417363188612996
Acta1 ENSMUSG00000031972 0.660661363813842 0.828136327451542 0.828136327451542 0.828136327451542 0.362627448818893 0.828136327451542
Tpm1 ENSMUSG00000032366 0.840457460024872 0.968520746487624 0.968520746487624 0.968520746487624 0.632829224190685 0.968520746487624
Rangrf ENSMUSG00000032892 0.393172125493285 0.589758188239928 0.106167173844366 0.318501521533098 0.695708998475684 0.695708998475684
Dysf ENSMUSG00000033788 0.420127671304031 0.630191506956047 0.213975596112697 0.630191506956047 0.767186945951021 0.767186945951021
Mybpc2 ENSMUSG00000038670 0.754208274196812 0.811109265590511 0.811109265590511 0.811109265590511 0.229908965945837 0.689726897837512
Trim72 ENSMUSG00000042828 0.426780137555561 0.984108363261062 0.73399432636013 0.984108363261062 0.984108363261062 0.984108363261062
Ttn ENSMUSG00000051747 0.50459520346277 0.879164917949511 0.75916415878315 0.879164917949511 0.879164917949511 0.879164917949511
Actn2 ENSMUSG00000052374 0.933704199733417 0.984198183387724 0.74004851085019 0.984198183387724 0.984198183387724 0.984198183387724
Myl1 ENSMUSG00000061816 0.531626463825679 0.612375956725726 0.612375956725726 0.612375956725726 0.032604052802775 0.0978121584083249
Cav3 ENSMUSG00000062694 0.528648116287533 0.827513616661448 0.827513616661448 0.827513616661448 0.706973526582707 0.827513616661448
Tnnt1 ENSMUSG00000064179 0.917834344074881 0.917834344074881 0.564518989098426 0.917834344074881 0.698132123334534 0.917834344074881
Cacng6 ENSMUSG00000078815 0.8134372209588 0.987244037432522 0.872910896977964 0.987244037432522 0.987244037432522 0.987244037432522

Cholesterol biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp51 ENSMUSG00000001467 0.452871858403942 0.946504904590542 0.946504904590542 0.946504904590542 0.883893324660543 0.946504904590542
Acat2 ENSMUSG00000023832 0.641224152175957 0.641224152175957 0.632808282266189 0.641224152175957 0.610443987035996 0.641224152175957
Tm7sf2 ENSMUSG00000024799 0.404412974565039 0.630341017643403 0.420227345095602 0.630341017643403 0.782327082059754 0.782327082059754
Nsdhl ENSMUSG00000031349 0.965370288821198 0.965370288821198 0.9088729501863 0.965370288821198 0.350924495069941 0.965370288821198
Sc4mol ENSMUSG00000031604 0.79118545377141 0.88701142705579 0.88701142705579 0.88701142705579 0.599043945326172 0.88701142705579
Dhcr24 ENSMUSG00000034926 0.678509413589362 0.846639516345943 0.499383034503666 0.846639516345943 0.846639516345943 0.846639516345943
Dhcr7 ENSMUSG00000058454 0.348688506314975 0.452682016275079 0.32103790115299 0.452682016275079 0.452682016275079 0.452682016275079

Glycogen metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gys1 ENSMUSG00000003865 0.320759848146992 0.878161215149676 0.585440810099784 0.878161215149676 0.908415934661294 0.908415934661294
Gyg ENSMUSG00000019528 0.849666614754592 0.977948989520894 0.588546522338463 0.977948989520894 0.977948989520894 0.977948989520894
Pygm ENSMUSG00000032648 0.610224044569715 0.971648828007182 0.933933482542211 0.971648828007182 0.971648828007182 0.971648828007182
Agl ENSMUSG00000033400 0.824734183521311 0.824734183521311 0.652148465047518 0.824734183521311 0.695914018257903 0.824734183521311
Phka1 ENSMUSG00000034055 0.984231708943008 0.984231708943008 0.782006240715006 0.984231708943008 0.921401548089613 0.984231708943008
Phkb ENSMUSG00000036879 0.799737795285277 0.799737795285277 0.306014925932717 0.799737795285277 0.649657393068437 0.799737795285277

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hk2 ENSMUSG00000000628 0.529886281855088 0.794829422782632 0.474398949479646 0.794829422782632 0.877649489117496 0.877649489117496
Cyp51 ENSMUSG00000001467 0.452871858403942 0.946504904590542 0.946504904590542 0.946504904590542 0.883893324660543 0.946504904590542
Akr1b3 ENSMUSG00000001642 0.661226232427195 0.840468164906683 0.834307586653806 0.840468164906683 0.840468164906683 0.840468164906683
Gmpr2 ENSMUSG00000002326 0.824803497127901 0.952772392121483 0.521710971213641 0.952772392121483 0.952772392121483 0.952772392121483
Slc25a1 ENSMUSG00000003528 0.309578747543534 0.464368121315301 0.24638397523616 0.464368121315301 0.815843103480362 0.815843103480362
Gys1 ENSMUSG00000003865 0.320759848146992 0.878161215149676 0.585440810099784 0.878161215149676 0.908415934661294 0.908415934661294
Nmrk2 ENSMUSG00000004939 0.572018737852217 0.856162455374755 0.856162455374755 0.856162455374755 0.744357137979439 0.856162455374755
Kdsr ENSMUSG00000009905 0.837331189823357 0.908851229989699 0.779264341265078 0.908851229989699 0.908851229989699 0.908851229989699
Pdhx ENSMUSG00000010914 0.135861871252294 0.407585613756883 0.72535165739096 0.72535165739096 0.707162361637502 0.72535165739096
Adssl1 ENSMUSG00000011148 0.719403049551864 0.791411383340349 0.512073095716585 0.791411383340349 0.791411383340349 0.791411383340349
Slc25a11 ENSMUSG00000014606 0.109654714330448 0.164482071495672 0.0476273771007837 0.142882131302351 0.392978883726563 0.392978883726563
Cers2 ENSMUSG00000015714 0.818921741891611 0.818921741891611 0.424802369954417 0.818921741891611 0.572310073972002 0.818921741891611
Adss ENSMUSG00000015961 0.397242735800211 0.887013357001742 0.837225068436136 0.887013357001742 0.887013357001742 0.887013357001742
Sdc4 ENSMUSG00000017009 0.514442370712878 0.771663556069317 0.443100359952178 0.771663556069317 0.868250285195168 0.868250285195168
Pnpo ENSMUSG00000018659 0.602169148837665 0.658369671645338 0.0212933523579156 0.0638800570737468 0.658369671645338 0.658369671645338
Mdh2 ENSMUSG00000019179 0.41721098230089 0.582674757551257 0.103158903079635 0.309476709238906 0.582674757551257 0.582674757551257
Gyg ENSMUSG00000019528 0.849666614754592 0.977948989520894 0.588546522338463 0.977948989520894 0.977948989520894 0.977948989520894
Pdk4 ENSMUSG00000019577 0.0595773168494446 0.0893659752741668 0.0105006607442286 0.0315019822326859 0.42329958285333 0.42329958285333
Pgam2 ENSMUSG00000020475 0.803488081744024 0.918260884175039 0.918260884175039 0.918260884175039 0.754962171678621 0.918260884175039
Nampt ENSMUSG00000020572 0.152696678403342 0.229045017605013 0.0464409495213126 0.139322848563938 0.834308571256967 0.834308571256967
Arsg ENSMUSG00000020604 0.788385099323123 0.788385099323123 0.317196403805788 0.596585028487301 0.397723352324868 0.596585028487301
Galk1 ENSMUSG00000020766 0.0902796195981084 0.25013503406605 0.166756689377367 0.25013503406605 0.959067447272555 0.959067447272555
Slc46a1 ENSMUSG00000020829 0.302071928631038 0.453107892946558 0.182133334076394 0.453107892946558 0.681336404472798 0.681336404472798
Ckmt2 ENSMUSG00000021622 0.32358686358372 0.485380295375579 0.538285521957261 0.538285521957261 0.0883697866914702 0.26510936007441
Psmd6 ENSMUSG00000021737 0.834250267098566 0.858936859291496 0.746110470712578 0.858936859291496 0.858936859291496 0.858936859291496
Glud1 ENSMUSG00000021794 0.320952436230156 0.481428654345234 0.202467520870727 0.481428654345234 0.837354324155961 0.837354324155961
Nudt13 ENSMUSG00000021809 0.104682124586282 0.314046373758845 0.742739074042904 0.742739074042904 0.440183733948179 0.660275600922268
Tkt ENSMUSG00000021957 0.45527552508508 0.558933957546336 0.144887081286411 0.434661243859232 0.558933957546336 0.558933957546336
Slc25a17 ENSMUSG00000022404 0.962208368007893 0.990547313638791 0.990547313638791 0.990547313638791 0.687151062407318 0.990547313638791
Adsl ENSMUSG00000022407 0.431654439681658 0.431654439681658 0.313309459731996 0.431654439681658 0.307600177772793 0.431654439681658
St3gal6 ENSMUSG00000022747 0.276690245797794 0.830070737393381 0.98740557010903 0.98740557010903 0.840417381084446 0.98740557010903
Acat2 ENSMUSG00000023832 0.641224152175957 0.641224152175957 0.632808282266189 0.641224152175957 0.610443987035996 0.641224152175957
Lpin2 ENSMUSG00000024052 0.176867536939679 0.530602610819038 0.501820618267796 0.698720663244666 0.698720663244666 0.698720663244666
Ip6k3 ENSMUSG00000024210 0.46312772437506 0.958089301787417 0.692482930443554 0.958089301787417 0.958089301787417 0.958089301787417
2410127L17Rik ENSMUSG00000024726 0.241558422172384 0.724675266517151 0.962229061152698 0.962229061152698 0.859031394789368 0.962229061152698
Tm7sf2 ENSMUSG00000024799 0.404412974565039 0.630341017643403 0.420227345095602 0.630341017643403 0.782327082059754 0.782327082059754
Chka ENSMUSG00000024843 0.962222460920168 0.962222460920168 0.415654799586714 0.962222460920168 0.812773962335868 0.962222460920168
Pcyt2 ENSMUSG00000025137 0.542765158884116 0.722377432997962 0.489150948371185 0.722377432997962 0.722377432997962 0.722377432997962
Slc16a3 ENSMUSG00000025161 0.713407973390739 0.837282631190211 0.837282631190211 0.837282631190211 0.607695360920409 0.837282631190211
Acbd5 ENSMUSG00000026781 0.137285730028298 0.411857190084895 0.743170626633803 0.809718452620778 0.809718452620778 0.809718452620778
Crat ENSMUSG00000026853 0.495280064680988 0.606371988502704 0.135059248701438 0.405177746104315 0.606371988502704 0.606371988502704
Hsd17b12 ENSMUSG00000027195 0.524511747296257 0.853987326699762 0.569324884466508 0.853987326699762 0.874551848235739 0.874551848235739
Pla2g12a ENSMUSG00000027999 0.51915760936776 0.681110061974765 0.161590636592744 0.484771909778233 0.681110061974765 0.681110061974765
Gale ENSMUSG00000028671 0.224436476398306 0.673309429194918 0.529974837352315 0.695842752583996 0.695842752583996 0.695842752583996
Mmachc ENSMUSG00000028690 0.609909825684169 0.609909825684169 0.441033328189567 0.609909825684169 0.417118456455469 0.609909825684169
Aacs ENSMUSG00000029482 0.524774519824757 0.663968020166544 0.205321051401248 0.615963154203744 0.663968020166544 0.663968020166544
Ckm ENSMUSG00000030399 0.728000987997703 0.728000987997703 0.658355622640328 0.728000987997703 0.0193692900726574 0.0581078702179721
Psmd8 ENSMUSG00000030591 0.203482587218095 0.610447761654286 0.896287365562489 0.981091315749911 0.981091315749911 0.981091315749911
Aldoa ENSMUSG00000030695 0.556090616919459 0.593936090318536 0.171716582318927 0.51514974695678 0.593936090318536 0.593936090318536
Nsdhl ENSMUSG00000031349 0.965370288821198 0.965370288821198 0.9088729501863 0.965370288821198 0.350924495069941 0.965370288821198
Sc4mol ENSMUSG00000031604 0.79118545377141 0.88701142705579 0.88701142705579 0.88701142705579 0.599043945326172 0.88701142705579
Elovl5 ENSMUSG00000032349 0.51138405733522 0.77596684904636 0.61554909480271 0.77596684904636 0.77596684904636 0.77596684904636
Gclc ENSMUSG00000032350 0.297438000210889 0.892314000632668 0.757950419416798 0.968442923961496 0.968442923961496 0.968442923961496
Pygm ENSMUSG00000032648 0.610224044569715 0.971648828007182 0.933933482542211 0.971648828007182 0.971648828007182 0.971648828007182
Ucp3 ENSMUSG00000032942 0.62939341858209 0.981030696489607 0.981030696489607 0.981030696489607 0.848998987380838 0.981030696489607
Agl ENSMUSG00000033400 0.824734183521311 0.824734183521311 0.652148465047518 0.824734183521311 0.695914018257903 0.824734183521311
Pdpr ENSMUSG00000033624 0.459865231366426 0.752134380552321 0.752134380552321 0.752134380552321 0.745990335201822 0.752134380552321
Phka1 ENSMUSG00000034055 0.984231708943008 0.984231708943008 0.782006240715006 0.984231708943008 0.921401548089613 0.984231708943008
Faah ENSMUSG00000034171 0.386583671092419 0.655405485663868 0.655405485663868 0.655405485663868 0.593960636137334 0.655405485663868
Dhcr24 ENSMUSG00000034926 0.678509413589362 0.846639516345943 0.499383034503666 0.846639516345943 0.846639516345943 0.846639516345943
Ptplb ENSMUSG00000035376 0.912001829268531 0.912001829268531 0.472069795176298 0.912001829268531 0.812761769000692 0.912001829268531
Cox8a ENSMUSG00000035885 0.846324437313378 0.846324437313378 0.595919584036583 0.846324437313378 0.692998679565229 0.846324437313378
Decr2 ENSMUSG00000036775 0.257665329007465 0.429246357610461 0.384331779618376 0.429246357610461 0.429246357610461 0.429246357610461
Phkb ENSMUSG00000036879 0.799737795285277 0.799737795285277 0.306014925932717 0.799737795285277 0.649657393068437 0.799737795285277
Coq10a ENSMUSG00000039914 0.185488304291837 0.52592664781794 0.35061776521196 0.52592664781794 0.955858165919783 0.955858165919783
Ppip5k2 ENSMUSG00000040648 0.915140765473803 0.930811873165517 0.610490436631671 0.930811873165517 0.930811873165517 0.930811873165517
Tmem86b ENSMUSG00000045282 0.556108955092226 0.806612694677942 0.296513208562862 0.806612694677942 0.806612694677942 0.806612694677942
Pla2g4e ENSMUSG00000050211 0.68495035176486 0.857200323203265 0.717966789808846 0.857200323203265 0.857200323203265 0.857200323203265
Phospho1 ENSMUSG00000050860 0.840474333736705 0.874558766547508 0.232122433644342 0.696367300933026 0.874558766547508 0.874558766547508
Sphk2 ENSMUSG00000057342 0.0784754843738117 0.235426453121435 0.382376140179715 0.501631208892123 0.501631208892123 0.501631208892123
Gapdh ENSMUSG00000057666 0.621432797553614 0.621432797553614 0.103743766779268 0.311231300337805 0.457546081189186 0.621432797553614
Dhcr7 ENSMUSG00000058454 0.348688506314975 0.452682016275079 0.32103790115299 0.452682016275079 0.452682016275079 0.452682016275079
Eno3 ENSMUSG00000060600 0.346808518223055 0.952791600896597 0.952791600896597 0.952791600896597 0.825070111616799 0.952791600896597
Hsd3b2 ENSMUSG00000063730 0.921373793826898 0.921373793826898 0.517123804336849 0.921373793826898 0.852804183325862 0.921373793826898
Rdh11 ENSMUSG00000066441 0.918204736055969 0.918204736055969 0.582806160590683 0.918204736055969 0.635668654799379 0.918204736055969
Ampd1 ENSMUSG00000070385 0.136058504045265 0.240611974830234 0.160407983220156 0.240611974830234 0.280065514247848 0.280065514247848
Amd1 ENSMUSG00000075232 0.416709499248637 0.82809780731503 0.772650791388587 0.82809780731503 0.82809780731503 0.82809780731503
Cpt1b ENSMUSG00000078937 0.321898818334591 0.779140322933077 0.779140322933077 0.779140322933077 0.62895029801752 0.779140322933077

Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc25a1 ENSMUSG00000003528 0.309578747543534 0.464368121315301 0.24638397523616 0.464368121315301 0.815843103480362 0.815843103480362
Slc25a11 ENSMUSG00000014606 0.109654714330448 0.164482071495672 0.0476273771007837 0.142882131302351 0.392978883726563 0.392978883726563
Mdh2 ENSMUSG00000019179 0.41721098230089 0.582674757551257 0.103158903079635 0.309476709238906 0.582674757551257 0.582674757551257
Pgam2 ENSMUSG00000020475 0.803488081744024 0.918260884175039 0.918260884175039 0.918260884175039 0.754962171678621 0.918260884175039
Aldoa ENSMUSG00000030695 0.556090616919459 0.593936090318536 0.171716582318927 0.51514974695678 0.593936090318536 0.593936090318536
Gapdh ENSMUSG00000057666 0.621432797553614 0.621432797553614 0.103743766779268 0.311231300337805 0.457546081189186 0.621432797553614
Eno3 ENSMUSG00000060600 0.346808518223055 0.952791600896597 0.952791600896597 0.952791600896597 0.825070111616799 0.952791600896597

Glycogen breakdown (glycogenolysis)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gyg ENSMUSG00000019528 0.849666614754592 0.977948989520894 0.588546522338463 0.977948989520894 0.977948989520894 0.977948989520894
Pygm ENSMUSG00000032648 0.610224044569715 0.971648828007182 0.933933482542211 0.971648828007182 0.971648828007182 0.971648828007182
Agl ENSMUSG00000033400 0.824734183521311 0.824734183521311 0.652148465047518 0.824734183521311 0.695914018257903 0.824734183521311
Phka1 ENSMUSG00000034055 0.984231708943008 0.984231708943008 0.782006240715006 0.984231708943008 0.921401548089613 0.984231708943008
Phkb ENSMUSG00000036879 0.799737795285277 0.799737795285277 0.306014925932717 0.799737795285277 0.649657393068437 0.799737795285277

Metabolism of carbohydrates

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hk2 ENSMUSG00000000628 0.529886281855088 0.794829422782632 0.474398949479646 0.794829422782632 0.877649489117496 0.877649489117496
Akr1b3 ENSMUSG00000001642 0.661226232427195 0.840468164906683 0.834307586653806 0.840468164906683 0.840468164906683 0.840468164906683
Slc25a1 ENSMUSG00000003528 0.309578747543534 0.464368121315301 0.24638397523616 0.464368121315301 0.815843103480362 0.815843103480362
Gys1 ENSMUSG00000003865 0.320759848146992 0.878161215149676 0.585440810099784 0.878161215149676 0.908415934661294 0.908415934661294
Slc25a11 ENSMUSG00000014606 0.109654714330448 0.164482071495672 0.0476273771007837 0.142882131302351 0.392978883726563 0.392978883726563
Sdc4 ENSMUSG00000017009 0.514442370712878 0.771663556069317 0.443100359952178 0.771663556069317 0.868250285195168 0.868250285195168
Mdh2 ENSMUSG00000019179 0.41721098230089 0.582674757551257 0.103158903079635 0.309476709238906 0.582674757551257 0.582674757551257
Gyg ENSMUSG00000019528 0.849666614754592 0.977948989520894 0.588546522338463 0.977948989520894 0.977948989520894 0.977948989520894
Pgam2 ENSMUSG00000020475 0.803488081744024 0.918260884175039 0.918260884175039 0.918260884175039 0.754962171678621 0.918260884175039
Galk1 ENSMUSG00000020766 0.0902796195981084 0.25013503406605 0.166756689377367 0.25013503406605 0.959067447272555 0.959067447272555
Tkt ENSMUSG00000021957 0.45527552508508 0.558933957546336 0.144887081286411 0.434661243859232 0.558933957546336 0.558933957546336
St3gal6 ENSMUSG00000022747 0.276690245797794 0.830070737393381 0.98740557010903 0.98740557010903 0.840417381084446 0.98740557010903
Gale ENSMUSG00000028671 0.224436476398306 0.673309429194918 0.529974837352315 0.695842752583996 0.695842752583996 0.695842752583996
Aldoa ENSMUSG00000030695 0.556090616919459 0.593936090318536 0.171716582318927 0.51514974695678 0.593936090318536 0.593936090318536
Pygm ENSMUSG00000032648 0.610224044569715 0.971648828007182 0.933933482542211 0.971648828007182 0.971648828007182 0.971648828007182
Agl ENSMUSG00000033400 0.824734183521311 0.824734183521311 0.652148465047518 0.824734183521311 0.695914018257903 0.824734183521311
Phka1 ENSMUSG00000034055 0.984231708943008 0.984231708943008 0.782006240715006 0.984231708943008 0.921401548089613 0.984231708943008
Phkb ENSMUSG00000036879 0.799737795285277 0.799737795285277 0.306014925932717 0.799737795285277 0.649657393068437 0.799737795285277
Gapdh ENSMUSG00000057666 0.621432797553614 0.621432797553614 0.103743766779268 0.311231300337805 0.457546081189186 0.621432797553614
Eno3 ENSMUSG00000060600 0.346808518223055 0.952791600896597 0.952791600896597 0.952791600896597 0.825070111616799 0.952791600896597

Class I peroxisomal membrane protein import

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pex3 ENSMUSG00000019809 0.968499850923403 0.968499850923403 0.314989045304353 0.932408898066068 0.621605932044045 0.932408898066068
Pex13 ENSMUSG00000020283 0.246097402320005 0.737877818125823 0.984244645602793 0.984244645602793 0.491918545417216 0.737877818125823
Slc25a17 ENSMUSG00000022404 0.962208368007893 0.990547313638791 0.990547313638791 0.990547313638791 0.687151062407318 0.990547313638791
Acbd5 ENSMUSG00000026781 0.137285730028298 0.411857190084895 0.743170626633803 0.809718452620778 0.809718452620778 0.809718452620778
Pex26 ENSMUSG00000067825 0.0963720163368817 0.289116049010645 0.479078803705933 0.649678779094824 0.649678779094824 0.649678779094824

Post-translational protein modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkcsh ENSMUSG00000003402 0.0953311218585688 0.142996682787853 0.00296935408367279 0.00890806225101837 0.739761042027988 0.739761042027988
Calr ENSMUSG00000003814 0.98110095931466 0.996846692422101 0.0341854236598362 0.102556270979509 0.996846692422101 0.996846692422101
Pex5 ENSMUSG00000005069 0.0239987468630653 0.0359981202945979 0.0212468295691336 0.0359981202945979 0.915033528020259 0.915033528020259
Fbxw9 ENSMUSG00000008167 0.159542391144544 0.478627173433633 0.548096798528294 0.822145197792441 0.880705061048284 0.880705061048284
Vdac3 ENSMUSG00000008892 0.764161721891523 0.927667902022012 0.338733928160766 0.927667902022012 0.927667902022012 0.927667902022012
Adamtsl4 ENSMUSG00000015850 0.940228180817542 0.940228180817542 0.519743063138189 0.779614594707284 0.105706536795386 0.317119610386158
Hsp90b1 ENSMUSG00000020048 0.122086437925427 0.366259313776281 0.278215116821077 0.417322675231616 0.5857963255755 0.5857963255755
Pex13 ENSMUSG00000020283 0.246097402320005 0.737877818125823 0.984244645602793 0.984244645602793 0.491918545417216 0.737877818125823
Cdc34 ENSMUSG00000020307 0.292576423687557 0.438864635531335 0.113606162755686 0.340818488267058 0.803492731299357 0.803492731299357
Canx ENSMUSG00000020368 0.0257571031258144 0.0772713093774433 0.408900146526408 0.613350219789612 0.713534532973954 0.713534532973954
Ube2b ENSMUSG00000020390 0.0850110896340122 0.255033268902037 0.532564720302981 0.770125409195491 0.770125409195491 0.770125409195491
Arsg ENSMUSG00000020604 0.788385099323123 0.788385099323123 0.317196403805788 0.596585028487301 0.397723352324868 0.596585028487301
Psmd6 ENSMUSG00000021737 0.834250267098566 0.858936859291496 0.746110470712578 0.858936859291496 0.858936859291496 0.858936859291496
Arf4 ENSMUSG00000021877 0.915065883890481 0.915065883890481 0.119009809003913 0.357029427011739 0.821913859133383 0.915065883890481
Galnt15 ENSMUSG00000021903 0.102657144892883 0.30797143467865 0.955897406440096 0.955897406440096 0.222807117345465 0.334210676018198
Dph3 ENSMUSG00000021905 0.591217024968586 0.965370408623043 0.965370408623043 0.965370408623043 0.899493750397513 0.965370408623043
Fbxo32 ENSMUSG00000022358 0.424495169057164 0.996848568643697 0.996848568643697 0.996848568643697 0.968507833627966 0.996848568643697
St3gal6 ENSMUSG00000022747 0.276690245797794 0.830070737393381 0.98740557010903 0.98740557010903 0.840417381084446 0.98740557010903
Adamts5 ENSMUSG00000022894 0.933888832979736 0.987394799668757 0.987394799668757 0.987394799668757 0.770185168003653 0.987394799668757
Pigp ENSMUSG00000022940 0.346399377306308 0.987398851502297 0.862050815571285 0.987398851502297 0.987398851502297 0.987398851502297
Cbx2 ENSMUSG00000025577 0.719219603342313 0.849648380441825 0.849648380441825 0.849648380441825 0.824984333093794 0.849648380441825
Cops5 ENSMUSG00000025917 0.285453706369288 0.428180559553932 0.0433510947359916 0.130053284207975 0.596455938020682 0.596455938020682
Sec16a ENSMUSG00000026924 0.596420789971754 0.91200937400569 0.91200937400569 0.91200937400569 0.890037425268283 0.91200937400569
Fbn1 ENSMUSG00000027204 0.799441009704551 0.799441009704551 0.472814246692453 0.799441009704551 0.604097716346384 0.799441009704551
Pdia3 ENSMUSG00000027248 0.871352656852258 0.896359796659511 0.629762238718294 0.896359796659511 0.896359796659511 0.896359796659511
Arfgap2 ENSMUSG00000027255 0.322857702721634 0.484286554082452 0.274869455052869 0.484286554082452 0.737239916118492 0.737239916118492
Sec22b ENSMUSG00000027879 0.350733661022054 0.797487736258743 0.797487736258743 0.797487736258743 0.535081558014158 0.797487736258743
Cyr61 ENSMUSG00000028195 0.17614652348643 0.528439570459289 0.429301075266034 0.643951612899051 0.971605308828864 0.971605308828864
Ptp4a2 ENSMUSG00000028788 0.336435176085519 0.977941196839113 0.977941196839113 0.977941196839113 0.959077341081844 0.977941196839113
Tuba8 ENSMUSG00000030137 0.890112195420569 0.937083512559368 0.794435270844449 0.937083512559368 0.937083512559368 0.937083512559368
Psmd8 ENSMUSG00000030591 0.203482587218095 0.610447761654286 0.896287365562489 0.981091315749911 0.981091315749911 0.981091315749911
Asb11 ENSMUSG00000031382 0.800040454015894 0.852516797596491 0.590935226094046 0.852516797596491 0.852516797596491 0.852516797596491
Asb5 ENSMUSG00000031519 0.707484109583513 0.952748118477101 0.137964885480957 0.413894656442871 0.952748118477101 0.952748118477101
Ank1 ENSMUSG00000031543 0.476560279208345 0.877617192709265 0.877617192709265 0.877617192709265 0.75499281612163 0.877617192709265
Tmed7 ENSMUSG00000033184 0.386671554291306 0.977961466233449 0.977961466233449 0.977961466233449 0.806634128509989 0.977961466233449
Asb13 ENSMUSG00000033781 0.965363272448182 0.965363272448182 0.506900494624374 0.760350741936561 0.406632493011776 0.760350741936561
Art3 ENSMUSG00000034842 0.326605906600974 0.640274792522309 0.809724956268306 0.809724956268306 0.426849861681539 0.640274792522309
Dcaf10 ENSMUSG00000035572 0.886994316392453 0.886994316392453 0.0636830719909143 0.191049215972743 0.812784080584945 0.886994316392453
Eef1a1 ENSMUSG00000037742 0.652206974721059 0.652206974721059 0.588214711834171 0.652206974721059 0.443182192533007 0.652206974721059
Asb10 ENSMUSG00000038204 0.569734523290689 0.652848309973908 0.421254448651072 0.652848309973908 0.652848309973908 0.652848309973908
Hrc ENSMUSG00000038239 0.958490981524188 0.958490981524188 0.457291286908005 0.958490981524188 0.840958095315758 0.958490981524188
B3galnt2 ENSMUSG00000039242 0.566583921194548 0.849875881791822 0.390868457926918 0.849875881791822 0.984254435801651 0.984254435801651
Mettl22 ENSMUSG00000039345 0.743191383565072 0.984256719255401 0.464916716081604 0.984256719255401 0.984256719255401 0.984256719255401
Foxo4 ENSMUSG00000042903 0.138230934285188 0.207346401427781 0.0309148216640281 0.0927444649920842 0.655435536045447 0.655435536045447
Fem1a ENSMUSG00000043683 0.563914447741601 0.933882125520398 0.725299835927468 0.933882125520398 0.933882125520398 0.933882125520398
Adamts12 ENSMUSG00000047497 0.130039838344132 0.390119515032397 0.820749224732326 0.820749224732326 0.465754466748804 0.698631700123206
Fbxo40 ENSMUSG00000047746 0.844716932999544 0.844716932999544 0.812227468857696 0.844716932999544 0.659833402617363 0.844716932999544
Slc17a5 ENSMUSG00000049624 0.687052279714559 0.746027337112659 0.746027337112659 0.746027337112659 0.522251374160038 0.746027337112659
Kbtbd13 ENSMUSG00000054978 0.740624257059048 0.891456684353901 0.367278638905221 0.891456684353901 0.891456684353901 0.891456684353901
Tgoln1 ENSMUSG00000056429 0.65813830423002 0.734241518871862 0.698661598492316 0.734241518871862 0.734241518871862 0.734241518871862
Usp13 ENSMUSG00000056900 0.664434668685368 0.76379002856957 0.76379002856957 0.76379002856957 0.723206038112173 0.76379002856957
Usp47 ENSMUSG00000059263 0.0703195253969942 0.210958576190983 0.681208838587931 0.773031432678793 0.773031432678793 0.773031432678793
Hist1h4h ENSMUSG00000060981 0.206688289489024 0.310032434233536 0.0252134609832463 0.0756403829497388 0.803627038375989 0.803627038375989
Copz1 ENSMUSG00000060992 0.0988460276576482 0.148269041486472 0.0282794270180651 0.0848382810541954 0.532429898942269 0.532429898942269
Wdr61 ENSMUSG00000061559 0.196391322211229 0.354857029131086 0.535006756438995 0.535006756438995 0.236571352754057 0.354857029131086
Klhl21 ENSMUSG00000073700 0.0778112563908786 0.116716884586318 0.0329005407019132 0.0987016221057396 0.788225767624446 0.788225767624446
Klhl41 ENSMUSG00000075307 0.585530792321262 0.585530792321262 0.506840074092688 0.585530792321262 0.509289318367719 0.585530792321262
Commd6 ENSMUSG00000075486 0.686851976446328 0.825080873105259 0.442897669336771 0.825080873105259 0.825080873105259 0.825080873105259
Rab9 ENSMUSG00000079316 0.350827371158541 0.526241056737812 0.257896841534325 0.526241056737812 0.846624899733831 0.846624899733831

Synthesis of PE

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lpin2 ENSMUSG00000024052 0.176867536939679 0.530602610819038 0.501820618267796 0.698720663244666 0.698720663244666 0.698720663244666
Chka ENSMUSG00000024843 0.962222460920168 0.962222460920168 0.415654799586714 0.962222460920168 0.812773962335868 0.962222460920168
Pcyt2 ENSMUSG00000025137 0.542765158884116 0.722377432997962 0.489150948371185 0.722377432997962 0.722377432997962 0.722377432997962
Phospho1 ENSMUSG00000050860 0.840474333736705 0.874558766547508 0.232122433644342 0.696367300933026 0.874558766547508 0.874558766547508

Neddylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxw9 ENSMUSG00000008167 0.159542391144544 0.478627173433633 0.548096798528294 0.822145197792441 0.880705061048284 0.880705061048284
Psmd6 ENSMUSG00000021737 0.834250267098566 0.858936859291496 0.746110470712578 0.858936859291496 0.858936859291496 0.858936859291496
Fbxo32 ENSMUSG00000022358 0.424495169057164 0.996848568643697 0.996848568643697 0.996848568643697 0.968507833627966 0.996848568643697
Cops5 ENSMUSG00000025917 0.285453706369288 0.428180559553932 0.0433510947359916 0.130053284207975 0.596455938020682 0.596455938020682
Psmd8 ENSMUSG00000030591 0.203482587218095 0.610447761654286 0.896287365562489 0.981091315749911 0.981091315749911 0.981091315749911
Asb11 ENSMUSG00000031382 0.800040454015894 0.852516797596491 0.590935226094046 0.852516797596491 0.852516797596491 0.852516797596491
Asb5 ENSMUSG00000031519 0.707484109583513 0.952748118477101 0.137964885480957 0.413894656442871 0.952748118477101 0.952748118477101
Asb13 ENSMUSG00000033781 0.965363272448182 0.965363272448182 0.506900494624374 0.760350741936561 0.406632493011776 0.760350741936561
Dcaf10 ENSMUSG00000035572 0.886994316392453 0.886994316392453 0.0636830719909143 0.191049215972743 0.812784080584945 0.886994316392453
Asb10 ENSMUSG00000038204 0.569734523290689 0.652848309973908 0.421254448651072 0.652848309973908 0.652848309973908 0.652848309973908
Fem1a ENSMUSG00000043683 0.563914447741601 0.933882125520398 0.725299835927468 0.933882125520398 0.933882125520398 0.933882125520398
Fbxo40 ENSMUSG00000047746 0.844716932999544 0.844716932999544 0.812227468857696 0.844716932999544 0.659833402617363 0.844716932999544
Kbtbd13 ENSMUSG00000054978 0.740624257059048 0.891456684353901 0.367278638905221 0.891456684353901 0.891456684353901 0.891456684353901
Klhl21 ENSMUSG00000073700 0.0778112563908786 0.116716884586318 0.0329005407019132 0.0987016221057396 0.788225767624446 0.788225767624446
Klhl41 ENSMUSG00000075307 0.585530792321262 0.585530792321262 0.506840074092688 0.585530792321262 0.509289318367719 0.585530792321262
Commd6 ENSMUSG00000075486 0.686851976446328 0.825080873105259 0.442897669336771 0.825080873105259 0.825080873105259 0.825080873105259

darkgreen

Coronavirus disease - COVID-19

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps5 ENSMUSG00000012848 0.137323601638126 0.291098551866443 0.758125894246956 0.758125894246956 0.194065701244295 0.291098551866443
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Mb21d1 ENSMUSG00000032344 0.779193090513379 0.965307232309759 0.965307232309759 0.965307232309759 0.949535403474954 0.965307232309759
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
C1qa ENSMUSG00000036887 0.249490358808716 0.669529156847566 0.669529156847566 0.669529156847566 0.504118505297814 0.669529156847566
C1qc ENSMUSG00000036896 0.228905135045486 0.452161420954431 0.394469890370354 0.452161420954431 0.452161420954431 0.452161420954431
C1qb ENSMUSG00000036905 0.862026196989381 0.862026196989381 0.742897828900491 0.862026196989381 0.527367937516455 0.862026196989381
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl10a ENSMUSG00000037805 0.943321925950768 0.943321925950768 0.770041683518075 0.943321925950768 0.770206898269682 0.943321925950768
Fau ENSMUSG00000038274 0.278550023925501 0.526087776255513 0.624281341171981 0.624281341171981 0.350725184170342 0.526087776255513
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl21 ENSMUSG00000041453 0.384463314154918 0.603306571316401 0.402204380877601 0.603306571316401 0.655458771068167 0.655458771068167
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
C5ar1 ENSMUSG00000049130 2.12809609905041e-05 6.38428829715122e-05 0.430872871373441 0.646309307060162 0.675020900274284 0.675020900274284
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Adam17 ENSMUSG00000052593 0.18021850482087 0.54065551446261 0.424706107033476 0.610076476006283 0.610076476006283 0.610076476006283
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl36 ENSMUSG00000057863 0.00613156234151418 0.0183946870245425 0.165726201822661 0.222861772876071 0.222861772876071 0.222861772876071
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps12 ENSMUSG00000061983 0.266248790199416 0.399373185299124 0.731283890664353 0.731283890664353 0.140511532882133 0.399373185299124
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl17 ENSMUSG00000062328 0.0827661223667349 0.248298367100205 0.202349326208385 0.269767219531398 0.269767219531398 0.269767219531398
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Rpl41 ENSMUSG00000093674 0.208166621403932 0.538648125432026 0.846623478451412 0.846623478451412 0.359098750288018 0.538648125432026
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Epstein-Barr virus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Cd44 ENSMUSG00000005087 0.658374818939291 0.843565520087994 0.843565520087994 0.843565520087994 0.501932506784184 0.843565520087994
Fcer2a ENSMUSG00000005540 0.0325901033148047 0.097770309944414 0.539241198508807 0.776934616243253 0.776934616243253 0.776934616243253
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Hes1 ENSMUSG00000022528 0.868336559968714 0.977961087418768 0.074715989943356 0.224147969830068 0.977961087418768 0.977961087418768
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Cr2 ENSMUSG00000026616 0.982657444165523 0.982657444165523 0.514885965573242 0.813122579350989 0.542081719567326 0.813122579350989
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Entpd1 ENSMUSG00000048120 0.0207366903422813 0.05725286216901 0.0996420436708778 0.0996420436708778 0.03816857477934 0.05725286216901
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Ribosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps5 ENSMUSG00000012848 0.137323601638126 0.291098551866443 0.758125894246956 0.758125894246956 0.194065701244295 0.291098551866443
Mrps18c ENSMUSG00000016833 0.231923360024569 0.566552888010418 0.613019785832768 0.613019785832768 0.377701925340278 0.566552888010418
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Mrpl24 ENSMUSG00000019710 0.98740208621757 0.98740208621757 0.624422605839828 0.936633908759743 0.30573016813831 0.917190504414931
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Mrpl36 ENSMUSG00000021607 0.0477019199324951 0.0988380481463397 0.0658920320975598 0.0988380481463397 0.160895255336733 0.160895255336733
Mrpl27 ENSMUSG00000024414 0.0425571614885346 0.127671484465604 0.219850338917394 0.329775508376091 0.621616258032259 0.621616258032259
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Mrps17 ENSMUSG00000034211 0.596475912834078 0.596475912834078 0.313158093930024 0.469737140895035 0.0938816830072371 0.281645049021711
Mrps10 ENSMUSG00000034729 0.82505669540927 0.82505669540927 0.388748936259133 0.82505669540927 0.65250975596809 0.82505669540927
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl10a ENSMUSG00000037805 0.943321925950768 0.943321925950768 0.770041683518075 0.943321925950768 0.770206898269682 0.943321925950768
Fau ENSMUSG00000038274 0.278550023925501 0.526087776255513 0.624281341171981 0.624281341171981 0.350725184170342 0.526087776255513
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl21 ENSMUSG00000041453 0.384463314154918 0.603306571316401 0.402204380877601 0.603306571316401 0.655458771068167 0.655458771068167
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl36 ENSMUSG00000057863 0.00613156234151418 0.0183946870245425 0.165726201822661 0.222861772876071 0.222861772876071 0.222861772876071
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps12 ENSMUSG00000061983 0.266248790199416 0.399373185299124 0.731283890664353 0.731283890664353 0.140511532882133 0.399373185299124
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl17 ENSMUSG00000062328 0.0827661223667349 0.248298367100205 0.202349326208385 0.269767219531398 0.269767219531398 0.269767219531398
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Rpl41 ENSMUSG00000093674 0.208166621403932 0.538648125432026 0.846623478451412 0.846623478451412 0.359098750288018 0.538648125432026
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Measles

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Slamf1 ENSMUSG00000015316 0.815669218239747 0.815669218239747 0.168274815138724 0.504824445416173 0.435136863346825 0.652705295020237
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Gnb2l1 ENSMUSG00000020372 0.599362813972648 0.599362813972648 0.556064453494769 0.599362813972648 0.194011583926232 0.582034751778696
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Msn ENSMUSG00000031207 0.632857647799575 0.632857647799575 0.342756368819007 0.535626944752326 0.357084629834884 0.535626944752326
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Cd209a ENSMUSG00000031494 0.889824441586438 0.889824441586438 0.635039927675588 0.889824441586438 0.821751695010895 0.889824441586438
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Eif2ak3 ENSMUSG00000031668 0.770220192856365 0.770220192856365 0.591262138582003 0.770220192856365 0.588508929767116 0.770220192856365
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Cd209b ENSMUSG00000065987 0.624893371661887 0.624893371661887 0.609047269065152 0.624893371661887 0.44145132683442 0.624893371661887
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574

Hematopoietic cell lineage

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Cd33 ENSMUSG00000004609 0.624162076310881 0.896366932455738 0.896366932455738 0.896366932455738 0.103692509204485 0.311077527613454
Cd44 ENSMUSG00000005087 0.658374818939291 0.843565520087994 0.843565520087994 0.843565520087994 0.501932506784184 0.843565520087994
Fcer2a ENSMUSG00000005540 0.0325901033148047 0.097770309944414 0.539241198508807 0.776934616243253 0.776934616243253 0.776934616243253
Epor ENSMUSG00000006235 0.200812051045155 0.602436153135466 0.524715013860017 0.783204721215732 0.783204721215732 0.783204721215732
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Cd5 ENSMUSG00000024669 0.434649898119878 0.53791337954027 0.53791337954027 0.53791337954027 0.275757387313808 0.53791337954027
Ms4a1 ENSMUSG00000024673 0.0314993457420767 0.0944980372262301 0.540410293610055 0.54839674200822 0.54839674200822 0.54839674200822
Cd7 ENSMUSG00000025163 0.378529362607734 0.572561031424807 0.544021508840422 0.572561031424807 0.572561031424807 0.572561031424807
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Cd55 ENSMUSG00000026399 0.60500208339292 0.794461398740089 0.794461398740089 0.794461398740089 0.649785541067507 0.794461398740089
Cr2 ENSMUSG00000026616 0.982657444165523 0.982657444165523 0.514885965573242 0.813122579350989 0.542081719567326 0.813122579350989
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Cd2 ENSMUSG00000027863 0.278580689866421 0.741358334683917 0.494238889789278 0.741358334683917 0.742752676431872 0.742752676431872
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Cd38 ENSMUSG00000029084 0.19875989812967 0.298139847194504 0.686857521633508 0.686857521633508 0.147250588561583 0.298139847194504
Gp9 ENSMUSG00000030054 0.00377310954923169 0.0113193286476951 0.619292967855541 0.635911427193935 0.635911427193935 0.635911427193935
Cd9 ENSMUSG00000030342 0.782287048401791 0.782287048401791 0.672602879829628 0.782287048401791 0.274831162294734 0.782287048401791
Cd22 ENSMUSG00000030577 0.71744671119612 0.85594787258356 0.745822501096633 0.85594787258356 0.85594787258356 0.85594787258356
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Cd37 ENSMUSG00000030798 0.0646183272693632 0.19385498180809 0.440463098232509 0.516459872533636 0.516459872533636 0.516459872533636
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Il7 ENSMUSG00000040329 0.707498587171359 0.707498587171359 0.602106908115829 0.707498587171359 0.464688969874476 0.707498587171359
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Cd24a ENSMUSG00000047139 0.943364349488709 0.993702375184352 0.993702375184352 0.993702375184352 0.965371011477973 0.993702375184352
Gp5 ENSMUSG00000047953 0.697011545864508 0.81649905272153 0.81649905272153 0.81649905272153 0.719462193986791 0.81649905272153
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Gypa ENSMUSG00000051839 0.808072775780216 0.954973991523955 0.145440938196746 0.436322814590237 0.954973991523955 0.954973991523955
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

NF-kappa B signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Ccl19 ENSMUSG00000071005 0.313038616853503 0.469557925280254 0.64409568095133 0.64409568095133 0.227268305163348 0.469557925280254
Bcl2a1b ENSMUSG00000089929 0.000594932491699785 0.00178479747509936 0.342703540633697 0.514055310950545 0.779235729098386 0.779235729098386
Ccl21a ENSMUSG00000094686 0.974775224406031 0.974775224406031 0.769761860735048 0.974775224406031 0.946418907773685 0.974775224406031
Edaradd ENSMUSG00000095105 0.415574514925377 0.761891218081588 0.761891218081588 0.761891218081588 0.620799018680336 0.761891218081588

Influenza A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Kpna2 ENSMUSG00000018362 0.175528060391153 0.526584181173458 0.695929704838194 0.740151595502956 0.740151595502956 0.740151595502956
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Rsad2 ENSMUSG00000020641 0.839722509138133 0.839722509138133 0.666481958412304 0.839722509138133 0.748094580276093 0.839722509138133
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Ciita ENSMUSG00000022504 0.700033709068584 0.700033709068584 0.613663065476282 0.700033709068584 0.545519913841226 0.700033709068584
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Nxt1 ENSMUSG00000036992 0.621284860765305 0.918244168391196 0.918244168391196 0.918244168391196 0.484109198446722 0.918244168391196
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Slc25a31 ENSMUSG00000069041 0.249872594936304 0.374808892404456 0.92373913611752 0.92373913611752 0.211084213111213 0.374808892404456
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

DNA replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Fen1 ENSMUSG00000024742 0.552732828858029 0.703990940968637 0.397683779546578 0.703990940968637 0.703990940968637 0.703990940968637
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Rnaseh2c ENSMUSG00000024925 0.262879298424384 0.394318947636575 0.00569408222104229 0.0170822466631269 0.481919491925605 0.481919491925605
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Pole3 ENSMUSG00000028394 0.849538701892552 0.849538701892552 0.504347928862361 0.756521893293541 0.294023477972154 0.756521893293541
Rpa2 ENSMUSG00000028884 0.170429986691734 0.511289960075203 0.971660795072063 0.971660795072063 0.865164540552543 0.971660795072063
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Ssbp1 ENSMUSG00000029911 0.865200085371835 0.86524266630788 0.86524266630788 0.86524266630788 0.840433880593143 0.86524266630788
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Rnaseh2a ENSMUSG00000052926 0.115347916550544 0.346043749651632 0.837390341019822 0.837390341019822 0.593657731920967 0.837390341019822
Lig1 ENSMUSG00000056394 0.85895180926901 0.85895180926901 0.203706628058387 0.611119884175162 0.713400622584613 0.85895180926901

Th17 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Tbx21 ENSMUSG00000001444 0.56348320228046 0.813270852721339 0.796670154103042 0.813270852721339 0.813270852721339 0.813270852721339
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Ahr ENSMUSG00000019256 0.641317522584743 0.791385020919456 0.791385020919456 0.791385020919456 0.479380026593462 0.791385020919456
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Irf4 ENSMUSG00000021356 0.774450460467845 0.774450460467845 0.745356699530584 0.774450460467845 0.180914376529554 0.542743129588663
Runx1 ENSMUSG00000022952 0.00316544057629907 0.00949632172889721 0.730543719478186 0.730543719478186 0.71873522241951 0.730543719478186
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Foxp3 ENSMUSG00000039521 0.82048901146847 0.989694584991145 0.86553259272103 0.989694584991145 0.989694584991145 0.989694584991145
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Cytokine-cytokine receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acvrl1 ENSMUSG00000000530 0.0932992538944453 0.139948880841668 0.0246386394673217 0.073915918401965 0.535158378520253 0.535158378520253
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Il16 ENSMUSG00000001741 0.611930619841571 0.611930619841571 0.395741565598107 0.593612348397161 0.0545775042155176 0.163732512646553
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Il17ra ENSMUSG00000002897 0.56149574604486 0.815817544635183 0.384634096605205 0.815817544635183 0.815817544635183 0.815817544635183
Ebi3 ENSMUSG00000003206 0.965320343149152 0.965320343149152 0.243627680256872 0.730883040770617 0.794410637753496 0.965320343149152
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Epor ENSMUSG00000006235 0.200812051045155 0.602436153135466 0.524715013860017 0.783204721215732 0.783204721215732 0.783204721215732
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Bmpr1a ENSMUSG00000021796 0.243016020681167 0.366919305543699 0.244612870362466 0.366919305543699 0.569595367830715 0.569595367830715
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Osmr ENSMUSG00000022146 0.000156058548173884 0.000468175644521653 0.852793209229563 0.852793209229563 0.313326543521735 0.469989815282602
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Cxcl13 ENSMUSG00000023078 0.847824688614068 0.847824688614068 0.465616242787921 0.757486759944996 0.504991173296664 0.757486759944996
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Tslp ENSMUSG00000024379 0.132548241130065 0.397644723390196 0.449777273641288 0.449777273641288 0.352429033437292 0.449777273641288
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Ccr1 ENSMUSG00000025804 0.792302154796113 0.792302154796113 0.446414406772984 0.694335669815142 0.462890446543428 0.694335669815142
Il18rap ENSMUSG00000026068 0.834403451006664 0.94159610832072 0.94159610832072 0.94159610832072 0.921566673834442 0.94159610832072
Il1rl1 ENSMUSG00000026069 0.261767210688227 0.751371986150376 0.751371986150376 0.751371986150376 0.594440646111953 0.751371986150376
Il18r1 ENSMUSG00000026070 0.376172574512653 0.430234124010001 0.430234124010001 0.430234124010001 0.362899627265156 0.430234124010001
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Bmp2 ENSMUSG00000027358 0.9464752056284 0.984253378994499 0.785268259291587 0.984253378994499 0.984253378994499 0.984253378994499
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Tnfsf8 ENSMUSG00000028362 0.572378473457636 0.585516979927963 0.535638996314391 0.585516979927963 0.585516979927963 0.585516979927963
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Tnfrsf9 ENSMUSG00000028965 0.551979116404505 0.849045304877206 0.778404727857629 0.849045304877206 0.849045304877206 0.849045304877206
Tnfrsf4 ENSMUSG00000029075 0.434051163203992 0.828145093874427 0.607731558231253 0.828145093874427 0.828145093874427 0.828145093874427
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Pf4 ENSMUSG00000029373 0.899343448384416 0.899343448384416 0.680807735581805 0.899343448384416 0.558898010233686 0.899343448384416
Cxcl9 ENSMUSG00000029417 0.811688464686606 0.836115366633473 0.753431796732797 0.836115366633473 0.836115366633473 0.836115366633473
Ccr9 ENSMUSG00000029530 0.339388545706885 0.673929254156722 0.820424128992458 0.820424128992458 0.449286169437815 0.673929254156722
Cd27 ENSMUSG00000030336 0.63681419423859 0.855166267900634 0.855166267900634 0.855166267900634 0.426478775983714 0.855166267900634
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Ccl22 ENSMUSG00000031779 0.412987362875792 0.592159046903127 0.592159046903127 0.592159046903127 0.277068969370578 0.592159046903127
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
Tnfsf9 ENSMUSG00000035678 0.868119017145407 0.930773105897805 0.930773105897805 0.930773105897805 0.352566427942107 0.930773105897805
Ccr7 ENSMUSG00000037944 0.255828981012523 0.767486943037568 0.808004745303223 0.808004745303223 0.784519651620392 0.808004745303223
Il7 ENSMUSG00000040329 0.707498587171359 0.707498587171359 0.602106908115829 0.707498587171359 0.464688969874476 0.707498587171359
Clcf1 ENSMUSG00000040663 0.172236824241387 0.25835523636208 0.987404528198245 0.987404528198245 0.0903124155374292 0.25835523636208
Tnfrsf18 ENSMUSG00000041954 0.565886325135964 0.848829487703946 0.398530238309786 0.848829487703946 0.93922116070972 0.93922116070972
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Ccr10 ENSMUSG00000044052 0.417964769369981 0.521910427444515 0.0994658181085909 0.298397454325773 0.521910427444515 0.521910427444515
Il1f9 ENSMUSG00000044103 0.550744278331147 0.826116417496721 0.248283517801562 0.744850553404687 0.838593798646873 0.838593798646873
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
Cxcr5 ENSMUSG00000047880 0.0685983316225568 0.20579499486767 0.268231649719138 0.268231649719138 0.157837100857088 0.236755651285632
Cxcr6 ENSMUSG00000048521 0.715643112937345 0.744313865805145 0.744313865805145 0.744313865805145 0.547904801202565 0.744313865805145
Ccr2 ENSMUSG00000049103 0.224099467905511 0.484257507078869 1 1 0.322838338052579 0.484257507078869
Cxcr3 ENSMUSG00000050232 0.864236852727334 0.864236852727334 0.854989491303756 0.864236852727334 0.346629814669672 0.864236852727334
Il31ra ENSMUSG00000050377 0.849572606020411 0.888445216680373 0.888445216680373 0.888445216680373 0.808998783693655 0.888445216680373
Gdf6 ENSMUSG00000051279 0.876555841155759 0.924593681718205 0.924593681718205 0.924593681718205 0.552811557010277 0.924593681718205
Lepr ENSMUSG00000057722 0.785250416494332 0.785250416494332 0.632786044186941 0.785250416494332 0.261059672298358 0.783179016895075
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Xcr1 ENSMUSG00000060509 0.97100348220911 0.97100348220911 0.562621752231069 0.843932628346603 0.403342929285652 0.843932628346603
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
Il1rl2 ENSMUSG00000070942 0.736254623457522 0.736254623457522 0.715767190861718 0.736254623457522 0.66882612900309 0.736254623457522
Ccl19 ENSMUSG00000071005 0.313038616853503 0.469557925280254 0.64409568095133 0.64409568095133 0.227268305163348 0.469557925280254
Csf2rb ENSMUSG00000071713 0.312733987134367 0.371376383337895 0.371376383337895 0.371376383337895 0.152377704632297 0.371376383337895
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
Tnfsf13 ENSMUSG00000089669 0.313250552160584 0.469875828240876 0.962219754077531 0.962219754077531 0.201092493304847 0.469875828240876
Ccl21a ENSMUSG00000094686 0.974775224406031 0.974775224406031 0.769761860735048 0.974775224406031 0.946418907773685 0.974775224406031
Tnfsf12 ENSMUSG00000097328 0.561531635206684 0.842297452810027 0.322979008125066 0.842297452810027 0.943358622315216 0.943358622315216

Th1 and Th2 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Tbx21 ENSMUSG00000001444 0.56348320228046 0.813270852721339 0.796670154103042 0.813270852721339 0.813270852721339 0.813270852721339
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Dll1 ENSMUSG00000014773 0.818909718008407 0.974810364509103 0.974810364509103 0.974810364509103 0.687150267748492 0.974810364509103
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Jag1 ENSMUSG00000027276 0.550571792775973 0.791283986332569 0.791283986332569 0.791283986332569 0.142624433303508 0.427873299910523
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Notch2 ENSMUSG00000027878 0.602224868763748 0.734239205174763 0.734239205174763 0.734239205174763 0.285634488186016 0.734239205174763
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Maml1 ENSMUSG00000050567 0.849727679593125 0.849727679593125 0.818911566463586 0.849727679593125 0.834281670694547 0.849727679593125
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Leishmaniasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Fcgr3 ENSMUSG00000059498 0.0780468839549562 0.234140651864869 0.65551682010443 0.65551682010443 0.212449878518021 0.318674817777032
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Osteoclast differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Spi1 ENSMUSG00000002111 0.305634506771214 0.466583643613941 0.571977206622312 0.571977206622312 0.311055762409294 0.466583643613941
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Lilra6 ENSMUSG00000030427 0.539296770535499 0.539296770535499 0.466255201605349 0.539296770535499 0.0874940183369075 0.262482055010722
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Junb ENSMUSG00000052837 0.0850774851972727 0.255232455591818 0.788387337290141 0.930807110778034 0.930807110778034 0.930807110778034
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Pirb ENSMUSG00000058818 0.332702388332113 0.499053582498169 0.880725310592458 0.880725310592458 0.313012553202442 0.499053582498169
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Fcgr3 ENSMUSG00000059498 0.0780468839549562 0.234140651864869 0.65551682010443 0.65551682010443 0.212449878518021 0.318674817777032
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Lilra5 ENSMUSG00000070873 0.855929610640207 0.855929610640207 0.471740515136299 0.855929610640207 0.840368362498668 0.855929610640207
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Gm14548 ENSMUSG00000074417 0.407777464874274 0.534334354372858 0.534334354372858 0.534334354372858 0.473292008332101 0.534334354372858
Sirpb1c ENSMUSG00000074677 0.579356914885657 0.869035372328486 0.283768706558931 0.851306119676793 0.984157520402225 0.984157520402225
Gm15922 ENSMUSG00000081665 0.297979071171844 0.739790515859404 0.939692122726795 0.939692122726795 0.493193677239603 0.739790515859404
Pira2 ENSMUSG00000089942 0.490037291108727 0.735055936663091 0.870817218757294 0.870817218757294 0.390389473033881 0.735055936663091
Sirpb1b ENSMUSG00000095028 0.884834703790803 0.910771720569585 0.910771720569585 0.910771720569585 0.402516263798805 0.910771720569585
Sirpb1a ENSMUSG00000095788 0.206684240616655 0.409326851364192 0.510394876146869 0.510394876146869 0.272884567576128 0.409326851364192

Intestinal immune network for IgA production

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Icosl ENSMUSG00000000732 0.943338320115267 0.943338320115267 0.501935949796012 0.752903924694018 0.230396936429296 0.691190809287889
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Ccr9 ENSMUSG00000029530 0.339388545706885 0.673929254156722 0.820424128992458 0.820424128992458 0.449286169437815 0.673929254156722
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Ccr10 ENSMUSG00000044052 0.417964769369981 0.521910427444515 0.0994658181085909 0.298397454325773 0.521910427444515 0.521910427444515
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376
Tnfsf13 ENSMUSG00000089669 0.313250552160584 0.469875828240876 0.962219754077531 0.962219754077531 0.201092493304847 0.469875828240876

Human T-cell leukemia virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Spi1 ENSMUSG00000002111 0.305634506771214 0.466583643613941 0.571977206622312 0.571977206622312 0.311055762409294 0.466583643613941
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Tcf3 ENSMUSG00000020167 0.2872265148422 0.861679544526601 0.764186055773375 0.940200872927201 0.940200872927201 0.940200872927201
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Map3k1 ENSMUSG00000021754 0.959038446258554 0.959038446258554 0.797459645757472 0.959038446258554 0.760871993358246 0.959038446258554
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Elk4 ENSMUSG00000026436 0.350873510216543 0.644116080964996 0.59667410332771 0.644116080964996 0.644116080964996 0.644116080964996
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Crtc2 ENSMUSG00000027936 0.905737557312377 0.959079998306599 0.462420433804495 0.959079998306599 0.959079998306599 0.959079998306599
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Tln1 ENSMUSG00000028465 0.572130411303441 0.65267344990602 0.0915572537081786 0.274671761124536 0.65267344990602 0.65267344990602
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Adcy7 ENSMUSG00000031659 0.767088974120291 0.767088974120291 0.402013836510905 0.603020754766358 0.166932517211185 0.500797551633555
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Ets1 ENSMUSG00000032035 0.309545240517341 0.346738289862591 0.135212858047756 0.346738289862591 0.346738289862591 0.346738289862591
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Tln2 ENSMUSG00000052698 0.821956609663064 0.821956609663064 0.422511538568199 0.821956609663064 0.770169895748685 0.821956609663064
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Slc25a31 ENSMUSG00000069041 0.249872594936304 0.374808892404456 0.92373913611752 0.92373913611752 0.211084213111213 0.374808892404456
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Inflammatory bowel disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Tbx21 ENSMUSG00000001444 0.56348320228046 0.813270852721339 0.796670154103042 0.813270852721339 0.813270852721339 0.813270852721339
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Il18rap ENSMUSG00000026068 0.834403451006664 0.94159610832072 0.94159610832072 0.94159610832072 0.921566673834442 0.94159610832072
Il18r1 ENSMUSG00000026070 0.376172574512653 0.430234124010001 0.430234124010001 0.430234124010001 0.362899627265156 0.430234124010001
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Foxp3 ENSMUSG00000039521 0.82048901146847 0.989694584991145 0.86553259272103 0.989694584991145 0.989694584991145 0.989694584991145
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

B cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd79a ENSMUSG00000003379 0.0234760756176181 0.0704282268528543 0.290616414871814 0.435924622307721 0.864931461359157 0.864931461359157
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Pik3ap1 ENSMUSG00000025017 0.99369399236377 0.99369399236377 0.899461146927869 0.99369399236377 0.754761678074681 0.99369399236377
Ifitm1 ENSMUSG00000025491 0.846628774219761 0.955920688024455 0.955920688024455 0.955920688024455 0.402092636721738 0.955920688024455
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Cr2 ENSMUSG00000026616 0.982657444165523 0.982657444165523 0.514885965573242 0.813122579350989 0.542081719567326 0.813122579350989
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Dapp1 ENSMUSG00000028159 0.921332971189463 0.921332971189463 0.695945259915935 0.921332971189463 0.352619245541218 0.921332971189463
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Cd72 ENSMUSG00000028459 0.984244185826138 0.984244185826138 0.652411908292052 0.984244185826138 0.974812040344884 0.984244185826138
Lilra6 ENSMUSG00000030427 0.539296770535499 0.539296770535499 0.466255201605349 0.539296770535499 0.0874940183369075 0.262482055010722
Cd22 ENSMUSG00000030577 0.71744671119612 0.85594787258356 0.745822501096633 0.85594787258356 0.85594787258356 0.85594787258356
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cd79b ENSMUSG00000040592 0.00661659993021874 0.0198497997906562 0.461073544589017 0.461073544589017 0.220163789450436 0.330245684175654
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Pirb ENSMUSG00000058818 0.332702388332113 0.499053582498169 0.880725310592458 0.880725310592458 0.313012553202442 0.499053582498169
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Lilra5 ENSMUSG00000070873 0.855929610640207 0.855929610640207 0.471740515136299 0.855929610640207 0.840368362498668 0.855929610640207
Rasgrp3 ENSMUSG00000071042 0.874424809318059 0.874424809318059 0.322933193689276 0.484399790533914 0.316821651693806 0.484399790533914
Gm14548 ENSMUSG00000074417 0.407777464874274 0.534334354372858 0.534334354372858 0.534334354372858 0.473292008332101 0.534334354372858
Gm15922 ENSMUSG00000081665 0.297979071171844 0.739790515859404 0.939692122726795 0.939692122726795 0.493193677239603 0.739790515859404
Pira2 ENSMUSG00000089942 0.490037291108727 0.735055936663091 0.870817218757294 0.870817218757294 0.390389473033881 0.735055936663091

Primary immunodeficiency

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Aire ENSMUSG00000000731 0.725452783894075 0.725452783894075 0.45912663796711 0.688689956950665 0.380179714164086 0.688689956950665
Cd79a ENSMUSG00000003379 0.0234760756176181 0.0704282268528543 0.290616414871814 0.435924622307721 0.864931461359157 0.864931461359157
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Ciita ENSMUSG00000022504 0.700033709068584 0.700033709068584 0.613663065476282 0.700033709068584 0.545519913841226 0.700033709068584
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Rfxank ENSMUSG00000036120 0.641318267764415 0.737227480026134 0.737227480026134 0.737227480026134 0.130066029017098 0.390198087051295
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Orai1 ENSMUSG00000049686 0.767211993950886 0.97796128174822 0.222950645168347 0.668851935505041 0.97796128174822 0.97796128174822
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857

Homologous recombination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rad50 ENSMUSG00000020380 0.67849686857224 0.67849686857224 0.369641700398189 0.67849686857224 0.607735129265013 0.67849686857224
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Uimc1 ENSMUSG00000025878 0.92765189897196 0.92765189897196 0.20375546249118 0.611266387473539 0.899489731129233 0.92765189897196
Bard1 ENSMUSG00000026196 0.954885243985506 0.954885243985506 0.949590901359229 0.954885243985506 0.789479820321452 0.954885243985506
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rad54l ENSMUSG00000028702 0.258215074721145 0.774645224163436 0.634902896954698 0.952354345432047 0.964798967808211 0.964798967808211
Rpa2 ENSMUSG00000028884 0.170429986691734 0.511289960075203 0.971660795072063 0.971660795072063 0.865164540552543 0.971660795072063
Ssbp1 ENSMUSG00000029911 0.865200085371835 0.86524266630788 0.86524266630788 0.86524266630788 0.840433880593143 0.86524266630788
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Rad54b ENSMUSG00000078773 0.731264470762685 0.773179856641001 0.566764642326267 0.773179856641001 0.773179856641001 0.773179856641001

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Cfp ENSMUSG00000001128 0.943359992701168 0.943359992701168 0.731278783609124 0.943359992701168 0.130993848922794 0.392981546768381
Daxx ENSMUSG00000002307 0.188637664560497 0.493086576099149 0.3287243840661 0.493086576099149 0.687195818423301 0.687195818423301
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Zfp959 ENSMUSG00000003198 0.968513778890915 0.968513778890915 0.716481655790359 0.968513778890915 0.384498461444967 0.968513778890915
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Zfp607 ENSMUSG00000020420 0.815306282817178 0.815306282817178 0.133056451541067 0.3991693546232 0.612324303914323 0.815306282817178
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Zfp54 ENSMUSG00000023882 0.107398467562758 0.322195402688274 0.280311939376316 0.420467909064474 0.580367987289222 0.580367987289222
Zfp51 ENSMUSG00000023892 0.235190921747482 0.352786382621223 0.117196972981545 0.351590918944635 0.874462752666159 0.874462752666159
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Cd74 ENSMUSG00000024610 0.491779704689238 0.643983510924004 0.2731036564511 0.643983510924004 0.643983510924004 0.643983510924004
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Sp100 ENSMUSG00000026222 0.684228399751986 0.746182300580058 0.746182300580058 0.746182300580058 0.506940699407348 0.746182300580058
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Eif2b1 ENSMUSG00000029388 0.684293286539936 0.955939628783549 0.955939628783549 0.955939628783549 0.380324608439837 0.955939628783549
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
9130019O22Rik ENSMUSG00000030823 0.211094606061014 0.633283818183042 0.429422546065353 0.64413381909803 0.661238333583704 0.661238333583704
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Eif2ak3 ENSMUSG00000031668 0.770220192856365 0.770220192856365 0.591262138582003 0.770220192856365 0.588508929767116 0.770220192856365
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Mb21d1 ENSMUSG00000032344 0.779193090513379 0.965307232309759 0.965307232309759 0.965307232309759 0.949535403474954 0.965307232309759
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Zfp113 ENSMUSG00000037007 0.48198061459868 0.722970921898021 0.764154844671624 0.764154844671624 0.174287827316986 0.522863481950959
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Zfp764 ENSMUSG00000045757 0.638361957982437 0.743139398734589 0.743139398734589 0.743139398734589 0.462375653282832 0.743139398734589
Pilra ENSMUSG00000046245 0.45967775817636 0.68951663726454 0.849616462733731 0.849616462733731 0.133144627932194 0.399433883796583
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Zfp455 ENSMUSG00000051037 0.764022731411663 0.85893458048499 0.474566507719613 0.85893458048499 0.85893458048499 0.85893458048499
Zfp52 ENSMUSG00000051341 0.78829254223511 0.78829254223511 0.440981173924791 0.78829254223511 0.687060498605718 0.78829254223511
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Zfp472 ENSMUSG00000053600 0.287402210782007 0.86220663234602 0.88697555467567 0.88697555467567 0.755089264429628 0.88697555467567
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Zfp747 ENSMUSG00000054381 0.81892510020135 0.81892510020135 0.32884530028021 0.493267950420315 0.322970117015547 0.493267950420315
AI987944 ENSMUSG00000056383 0.046943389408073 0.083212566418127 0.0554750442787513 0.083212566418127 0.408216767392623 0.408216767392623
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Zfp53 ENSMUSG00000057409 0.596604814915064 0.855859911520181 0.855859911520181 0.855859911520181 0.791279357193469 0.855859911520181
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Zfp119a ENSMUSG00000057835 0.205317234984592 0.615951704953776 0.788356183943894 0.843538512698807 0.843538512698807 0.843538512698807
Zfp595 ENSMUSG00000057842 0.122808665645878 0.368425996937634 0.484265413652523 0.726398120478784 0.727900911027923 0.727900911027923
Rsl1 ENSMUSG00000058900 0.0584419490614589 0.175325847184377 0.849689489598832 0.849689489598832 0.54276353235559 0.814145298533385
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Alyref2 ENSMUSG00000060244 0.785338673845993 0.785338673845993 0.55618687816958 0.785338673845993 0.484387469286486 0.785338673845993
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Zfp119b ENSMUSG00000062101 0.371671542545877 0.908829666741265 0.858968595018339 0.908829666741265 0.908829666741265 0.908829666741265
Zfp534 ENSMUSG00000062518 0.0224847052553563 0.067454115766069 0.222479656035295 0.333719484052942 0.958900672681177 0.958900672681177
Zfp677 ENSMUSG00000062743 0.50693304889277 0.50693304889277 0.365429855786619 0.50693304889277 0.354988555585396 0.50693304889277
Zfp69 ENSMUSG00000064141 0.800392829713434 0.974789757595072 0.974789757595072 0.974789757595072 0.758158038538366 0.974789757595072
Gm13051 ENSMUSG00000066009 0.48750656524676 0.73125984787014 0.347454430063698 0.73125984787014 0.945095966934296 0.945095966934296
Pilrb2 ENSMUSG00000066682 0.660859924388969 0.861759083457202 0.861759083457202 0.861759083457202 0.50047673962874 0.861759083457202
Pilrb1 ENSMUSG00000066684 0.996848483000984 0.996848483000984 0.790882778937764 0.996848483000984 0.335006205720893 0.996848483000984
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Gm13139 ENSMUSG00000067916 0.330749239687458 0.496123859531186 0.155027478940348 0.465082436821045 0.890117427523571 0.890117427523571
Zfp825 ENSMUSG00000069208 0.399645580080089 0.540343317939559 0.540343317939559 0.540343317939559 0.491602332677673 0.540343317939559
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
AW146154 ENSMUSG00000074166 0.984254715353976 0.984254715353976 0.585729235432128 0.984254715353976 0.794383681659508 0.984254715353976
Zfp808 ENSMUSG00000074867 0.890094078521974 0.890094078521974 0.540406690161692 0.810610035242537 0.535073334792912 0.810610035242537
Gm13157 ENSMUSG00000078495 0.624240512978282 0.936360769467423 0.102180821199897 0.306542463599692 0.968503813129991 0.968503813129991
Gm13212 ENSMUSG00000078502 0.459121900778597 0.614422682067283 0.0193616841614488 0.0580850524843463 0.614422682067283 0.614422682067283
Zfp456 ENSMUSG00000078995 0.13010991999385 0.39032975998155 0.499411678679109 0.718043510024566 0.718043510024566 0.718043510024566
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376
Zfp97 ENSMUSG00000095990 0.266401009134915 0.399601513702372 0.254521957181761 0.399601513702372 0.479504814652902 0.479504814652902
Zfp433 ENSMUSG00000096795 0.249587181016902 0.444687616335941 0.296458410890627 0.444687616335941 0.710577880375194 0.710577880375194
Zfp953 ENSMUSG00000098905 0.646737906949002 0.849584375011497 0.849584375011497 0.849584375011497 0.433724397021824 0.849584375011497

NOD-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Mefv ENSMUSG00000022534 0.840840226570052 0.840840226570052 0.747234696137759 0.840840226570052 0.266684635738278 0.800053907214833
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Gbp3 ENSMUSG00000028268 0.883875966979969 0.883875966979969 0.770221190480892 0.883875966979969 0.390982699460123 0.883875966979969
Gbp2 ENSMUSG00000028270 0.701370521604441 0.97478550829891 0.97478550829891 0.97478550829891 0.563371638375463 0.97478550829891
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Pstpip1 ENSMUSG00000032322 0.384522741621919 0.576784112432878 0.695935481794803 0.695935481794803 0.0602137721255987 0.180641316376796
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Gm4955 ENSMUSG00000037849 0.886282898593019 0.977798632988534 0.977798632988534 0.977798632988534 0.712485832640406 0.977798632988534
Aim2 ENSMUSG00000037860 0.731086205696361 0.871350032640993 0.455273305926355 0.871350032640993 0.871350032640993 0.871350032640993
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Nlrc4 ENSMUSG00000039193 0.858843988828162 0.9747287565996 0.9747287565996 0.9747287565996 0.539701382478747 0.9747287565996
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Gbp7 ENSMUSG00000040253 0.952751022099644 0.952751022099644 0.812741605770351 0.952751022099644 0.399654931023229 0.952751022099644
Gbp5 ENSMUSG00000040264 0.535123307021759 0.535123307021759 0.43388218705297 0.535123307021759 0.0980771792656282 0.294231537796885
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Card6 ENSMUSG00000041849 0.623863904124569 0.623863904124569 0.222342098402187 0.531861596128139 0.354574397418759 0.531861596128139
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
Nlrp1a ENSMUSG00000069830 0.522940617415826 0.784410926123738 0.893200773561383 0.893200773561383 0.35492385366701 0.784410926123738
Nlrp1b ENSMUSG00000070390 0.429666395630238 0.557731899326012 0.557731899326012 0.557731899326012 0.419623122807428 0.557731899326012
AI607873 ENSMUSG00000073490 0.00230288130891104 0.00690864392673312 0.271274908141318 0.406912362211978 0.543077629271251 0.543077629271251
Naip2 ENSMUSG00000078945 0.0213468735252908 0.0640406205758724 0.824782352446474 0.824782352446474 0.362974420100341 0.544461630150511

Cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Smc1b ENSMUSG00000022432 0.526038269267884 0.931586764505415 0.931586764505415 0.931586764505415 0.921799181408279 0.931586764505415
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Bub1 ENSMUSG00000027379 0.0621220548434211 0.186366164530263 0.239963066366849 0.359944599550273 0.379350764070384 0.379350764070384
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Ttk ENSMUSG00000038379 0.281134671401957 0.618968103452911 0.41264540230194 0.618968103452911 0.626340349318261 0.626340349318261
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214

Tuberculosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Lsp1 ENSMUSG00000018819 0.899475056706983 0.899475056706983 0.580288316975844 0.870432475463766 0.311251477052262 0.870432475463766
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ciita ENSMUSG00000022504 0.700033709068584 0.700033709068584 0.613663065476282 0.700033709068584 0.545519913841226 0.700033709068584
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
Nfya ENSMUSG00000023994 0.224439909620963 0.535611678419091 0.834298724435482 0.834298724435482 0.357074452279394 0.535611678419091
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Cd74 ENSMUSG00000024610 0.491779704689238 0.643983510924004 0.2731036564511 0.643983510924004 0.643983510924004 0.643983510924004
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Coro1a ENSMUSG00000030707 0.355037537295033 0.561593589035712 0.561593589035712 0.561593589035712 0.47460318326064 0.561593589035712
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Itgax ENSMUSG00000030789 0.598006607913018 0.598006607913018 0.332626450570772 0.560169820622968 0.373446547081979 0.560169820622968
Cd209a ENSMUSG00000031494 0.889824441586438 0.889824441586438 0.635039927675588 0.889824441586438 0.821751695010895 0.889824441586438
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Rfxank ENSMUSG00000036120 0.641318267764415 0.737227480026134 0.737227480026134 0.737227480026134 0.130066029017098 0.390198087051295
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Fcgr3 ENSMUSG00000059498 0.0780468839549562 0.234140651864869 0.65551682010443 0.65551682010443 0.212449878518021 0.318674817777032
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Sphk1 ENSMUSG00000061878 0.298016874176902 0.447307795578438 0.298205197052292 0.447307795578438 0.99683985061631 0.99683985061631
Cd209b ENSMUSG00000065987 0.624893371661887 0.624893371661887 0.609047269065152 0.624893371661887 0.44145132683442 0.624893371661887
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Yersinia infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Fyb ENSMUSG00000022148 0.0121348140217551 0.0364044420652652 0.68404209569131 0.68404209569131 0.46432641922888 0.68404209569131
Mefv ENSMUSG00000022534 0.840840226570052 0.840840226570052 0.747234696137759 0.840840226570052 0.266684635738278 0.800053907214833
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Was ENSMUSG00000031165 0.519172085377981 0.519172085377981 0.358941363716733 0.519172085377981 0.426510036593108 0.519172085377981
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Nlrc4 ENSMUSG00000039193 0.858843988828162 0.9747287565996 0.9747287565996 0.9747287565996 0.539701382478747 0.9747287565996
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Arf6 ENSMUSG00000044147 0.58028691959072 0.9811078280034 0.812759716016395 0.9811078280034 0.9811078280034 0.9811078280034
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115

Viral protein interaction with cytokine and cytokine receptor

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
Cxcl13 ENSMUSG00000023078 0.847824688614068 0.847824688614068 0.465616242787921 0.757486759944996 0.504991173296664 0.757486759944996
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Ccr1 ENSMUSG00000025804 0.792302154796113 0.792302154796113 0.446414406772984 0.694335669815142 0.462890446543428 0.694335669815142
Il18rap ENSMUSG00000026068 0.834403451006664 0.94159610832072 0.94159610832072 0.94159610832072 0.921566673834442 0.94159610832072
Il18r1 ENSMUSG00000026070 0.376172574512653 0.430234124010001 0.430234124010001 0.430234124010001 0.362899627265156 0.430234124010001
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Pf4 ENSMUSG00000029373 0.899343448384416 0.899343448384416 0.680807735581805 0.899343448384416 0.558898010233686 0.899343448384416
Cxcl9 ENSMUSG00000029417 0.811688464686606 0.836115366633473 0.753431796732797 0.836115366633473 0.836115366633473 0.836115366633473
Ccr9 ENSMUSG00000029530 0.339388545706885 0.673929254156722 0.820424128992458 0.820424128992458 0.449286169437815 0.673929254156722
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Ccl22 ENSMUSG00000031779 0.412987362875792 0.592159046903127 0.592159046903127 0.592159046903127 0.277068969370578 0.592159046903127
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
Ccr7 ENSMUSG00000037944 0.255828981012523 0.767486943037568 0.808004745303223 0.808004745303223 0.784519651620392 0.808004745303223
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Ccr10 ENSMUSG00000044052 0.417964769369981 0.521910427444515 0.0994658181085909 0.298397454325773 0.521910427444515 0.521910427444515
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
Cxcr5 ENSMUSG00000047880 0.0685983316225568 0.20579499486767 0.268231649719138 0.268231649719138 0.157837100857088 0.236755651285632
Ccr2 ENSMUSG00000049103 0.224099467905511 0.484257507078869 1 1 0.322838338052579 0.484257507078869
Cxcr3 ENSMUSG00000050232 0.864236852727334 0.864236852727334 0.854989491303756 0.864236852727334 0.346629814669672 0.864236852727334
Xcr1 ENSMUSG00000060509 0.97100348220911 0.97100348220911 0.562621752231069 0.843932628346603 0.403342929285652 0.843932628346603
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Ccl19 ENSMUSG00000071005 0.313038616853503 0.469557925280254 0.64409568095133 0.64409568095133 0.227268305163348 0.469557925280254
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
Ccl21a ENSMUSG00000094686 0.974775224406031 0.974775224406031 0.769761860735048 0.974775224406031 0.946418907773685 0.974775224406031

Chemokine signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Dock2 ENSMUSG00000020143 0.158484207163789 0.462690541745841 0.534861803540552 0.534861803540552 0.308460361163894 0.462690541745841
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Cxcl13 ENSMUSG00000023078 0.847824688614068 0.847824688614068 0.465616242787921 0.757486759944996 0.504991173296664 0.757486759944996
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Ccr1 ENSMUSG00000025804 0.792302154796113 0.792302154796113 0.446414406772984 0.694335669815142 0.462890446543428 0.694335669815142
Pard3 ENSMUSG00000025812 0.344777907710299 0.583454163725556 0.388969442483704 0.583454163725556 0.927675899565806 0.927675899565806
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Fgr ENSMUSG00000028874 0.815052467550623 0.835991601564856 0.835991601564856 0.835991601564856 0.68832951884056 0.835991601564856
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Pf4 ENSMUSG00000029373 0.899343448384416 0.899343448384416 0.680807735581805 0.899343448384416 0.558898010233686 0.899343448384416
Cxcl9 ENSMUSG00000029417 0.811688464686606 0.836115366633473 0.753431796732797 0.836115366633473 0.836115366633473 0.836115366633473
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Ccr9 ENSMUSG00000029530 0.339388545706885 0.673929254156722 0.820424128992458 0.820424128992458 0.449286169437815 0.673929254156722
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Was ENSMUSG00000031165 0.519172085377981 0.519172085377981 0.358941363716733 0.519172085377981 0.426510036593108 0.519172085377981
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Adcy7 ENSMUSG00000031659 0.767088974120291 0.767088974120291 0.402013836510905 0.603020754766358 0.166932517211185 0.500797551633555
Ccl22 ENSMUSG00000031779 0.412987362875792 0.592159046903127 0.592159046903127 0.592159046903127 0.277068969370578 0.592159046903127
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
Ccr7 ENSMUSG00000037944 0.255828981012523 0.767486943037568 0.808004745303223 0.808004745303223 0.784519651620392 0.808004745303223
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Shc1 ENSMUSG00000042626 0.524862972514124 0.646974935518976 0.646974935518976 0.646974935518976 0.545711178736166 0.646974935518976
Ccr10 ENSMUSG00000044052 0.417964769369981 0.521910427444515 0.0994658181085909 0.298397454325773 0.521910427444515 0.521910427444515
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Cxcr5 ENSMUSG00000047880 0.0685983316225568 0.20579499486767 0.268231649719138 0.268231649719138 0.157837100857088 0.236755651285632
Cxcr6 ENSMUSG00000048521 0.715643112937345 0.744313865805145 0.744313865805145 0.744313865805145 0.547904801202565 0.744313865805145
Ccr2 ENSMUSG00000049103 0.224099467905511 0.484257507078869 1 1 0.322838338052579 0.484257507078869
Cxcr3 ENSMUSG00000050232 0.864236852727334 0.864236852727334 0.854989491303756 0.864236852727334 0.346629814669672 0.864236852727334
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Xcr1 ENSMUSG00000060509 0.97100348220911 0.97100348220911 0.562621752231069 0.843932628346603 0.403342929285652 0.843932628346603
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Ccl19 ENSMUSG00000071005 0.313038616853503 0.469557925280254 0.64409568095133 0.64409568095133 0.227268305163348 0.469557925280254
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
Ccl21a ENSMUSG00000094686 0.974775224406031 0.974775224406031 0.769761860735048 0.974775224406031 0.946418907773685 0.974775224406031

Toxoplasmosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ciita ENSMUSG00000022504 0.700033709068584 0.700033709068584 0.613663065476282 0.700033709068584 0.545519913841226 0.700033709068584
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Tlr11 ENSMUSG00000051969 0.821942078224907 0.821942078224907 0.484267884390184 0.74322422622368 0.495482817482453 0.74322422622368
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Igtp ENSMUSG00000078853 0.246429183340892 0.737293227554429 0.849627015604469 0.849627015604469 0.49152881836962 0.737293227554429
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Cellular senescence

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Foxm1 ENSMUSG00000001517 0.843514943104096 0.843514943104096 0.365399252692269 0.843514943104096 0.812736943893088 0.843514943104096
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Mybl2 ENSMUSG00000017861 0.775967142068513 0.921298979822017 0.695941548858802 0.921298979822017 0.921298979822017 0.921298979822017
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Traf3ip2 ENSMUSG00000019842 0.23207605795213 0.69622817385639 0.743186208640941 0.896377207714365 0.896377207714365 0.896377207714365
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Sirt1 ENSMUSG00000020063 0.791414478789436 0.915141605502986 0.831202801623218 0.915141605502986 0.915141605502986 0.915141605502986
Rad50 ENSMUSG00000020380 0.67849686857224 0.67849686857224 0.369641700398189 0.67849686857224 0.607735129265013 0.67849686857224
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Zfp36l1 ENSMUSG00000021127 0.344658554876765 0.56958665186549 0.537830619213933 0.56958665186549 0.56958665186549 0.56958665186549
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Rassf5 ENSMUSG00000026430 0.684298491773043 0.865219472454728 0.865219472454728 0.865219472454728 0.441037520361291 0.865219472454728
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Ets1 ENSMUSG00000032035 0.309545240517341 0.346738289862591 0.135212858047756 0.346738289862591 0.346738289862591 0.346738289862591
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Hipk4 ENSMUSG00000040424 0.172716175090382 0.518148525271146 0.542565237868126 0.81384785680219 0.899387524567892 0.899387524567892
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Zfp36l2 ENSMUSG00000045817 0.719378126299164 0.977943613675909 0.93388020661966 0.977943613675909 0.977943613675909 0.977943613675909
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Rras2 ENSMUSG00000055723 0.959084193111151 0.959084193111151 0.499434225947636 0.959084193111151 0.893259660574228 0.959084193111151
Lin9 ENSMUSG00000058729 0.607695601733744 0.803630088586773 0.332733809251367 0.803630088586773 0.803630088586773 0.803630088586773
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Slc25a31 ENSMUSG00000069041 0.249872594936304 0.374808892404456 0.92373913611752 0.92373913611752 0.211084213111213 0.374808892404456
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853

Antigen processing and presentation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Ciita ENSMUSG00000022504 0.700033709068584 0.700033709068584 0.613663065476282 0.700033709068584 0.545519913841226 0.700033709068584
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfya ENSMUSG00000023994 0.224439909620963 0.535611678419091 0.834298724435482 0.834298724435482 0.357074452279394 0.535611678419091
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Cd74 ENSMUSG00000024610 0.491779704689238 0.643983510924004 0.2731036564511 0.643983510924004 0.643983510924004 0.643983510924004
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Ifi30 ENSMUSG00000031838 0.136196168338928 0.408588505016783 0.362468437705198 0.543702656557797 0.635093801711498 0.635093801711498
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Rfxank ENSMUSG00000036120 0.641318267764415 0.737227480026134 0.737227480026134 0.737227480026134 0.130066029017098 0.390198087051295
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Toll-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Cxcl9 ENSMUSG00000029417 0.811688464686606 0.836115366633473 0.753431796732797 0.836115366633473 0.836115366633473 0.836115366633473
Irf5 ENSMUSG00000029771 0.627117621779133 0.627117621779133 0.0556446899027774 0.166934069708332 0.414790203246615 0.622185304869923
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042

Cytosolic DNA-sensing pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Zbp1 ENSMUSG00000027514 0.865080865029008 0.865080865029008 0.510714288705774 0.865080865029008 0.637230397483361 0.865080865029008
Polr3c ENSMUSG00000028099 0.716446378602089 0.716446378602089 0.669791711571956 0.716446378602089 0.550773488885218 0.716446378602089
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Polr1d ENSMUSG00000029642 0.0848494993214706 0.127274248982206 0.00917440138128852 0.0275232041438656 0.968510527168435 0.968510527168435
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Mb21d1 ENSMUSG00000032344 0.779193090513379 0.965307232309759 0.965307232309759 0.965307232309759 0.949535403474954 0.965307232309759
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Polr3b ENSMUSG00000034453 0.788393174127829 0.92140590417822 0.92140590417822 0.92140590417822 0.846654855910342 0.92140590417822
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Polr3g ENSMUSG00000035834 0.0641125140282136 0.192337542084641 0.84973061480391 0.84973061480391 0.767089226979462 0.84973061480391
Aim2 ENSMUSG00000037860 0.731086205696361 0.871350032640993 0.455273305926355 0.871350032640993 0.871350032640993 0.871350032640993
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Trex1 ENSMUSG00000049734 0.0894610083511734 0.182717514829005 0.12181167655267 0.182717514829005 0.371387497675615 0.371387497675615
Polr1c ENSMUSG00000067148 0.519748758068391 0.63849341200239 0.594003694054131 0.63849341200239 0.63849341200239 0.63849341200239

Mismatch repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rpa2 ENSMUSG00000028884 0.170429986691734 0.511289960075203 0.971660795072063 0.971660795072063 0.865164540552543 0.971660795072063
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Ssbp1 ENSMUSG00000029911 0.865200085371835 0.86524266630788 0.86524266630788 0.86524266630788 0.840433880593143 0.86524266630788
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Lig1 ENSMUSG00000056394 0.85895180926901 0.85895180926901 0.203706628058387 0.611119884175162 0.713400622584613 0.85895180926901

T cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Ctla4 ENSMUSG00000026011 0.754397185072788 0.987229400844189 0.929833477154719 0.987229400844189 0.987229400844189 0.987229400844189
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772

C-type lectin receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Lsp1 ENSMUSG00000018819 0.899475056706983 0.899475056706983 0.580288316975844 0.870432475463766 0.311251477052262 0.870432475463766
Irf1 ENSMUSG00000018899 0.326707294677525 0.490060942016288 0.761181164989444 0.761181164989444 0.273095744558522 0.490060942016288
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Clec4n ENSMUSG00000023349 0.66366094094944 0.911880328065958 0.911880328065958 0.911880328065958 0.788291202279061 0.911880328065958
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Clec4b1 ENSMUSG00000030147 0.22922165224967 0.51305545899669 0.933532321349815 0.933532321349815 0.34203697266446 0.51305545899669
Clec1b ENSMUSG00000030159 0.109815078009729 0.329445234029186 0.905662764674105 0.905662764674105 0.452311992223792 0.678467988335688
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Cd209a ENSMUSG00000031494 0.889824441586438 0.889824441586438 0.635039927675588 0.889824441586438 0.821751695010895 0.889824441586438
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Ccl22 ENSMUSG00000031779 0.412987362875792 0.592159046903127 0.592159046903127 0.592159046903127 0.277068969370578 0.592159046903127
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Rras2 ENSMUSG00000055723 0.959084193111151 0.959084193111151 0.499434225947636 0.959084193111151 0.893259660574228 0.959084193111151
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Cd209b ENSMUSG00000065987 0.624893371661887 0.624893371661887 0.609047269065152 0.624893371661887 0.44145132683442 0.624893371661887
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355

Hepatitis B

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Map3k1 ENSMUSG00000021754 0.959038446258554 0.959038446258554 0.797459645757472 0.959038446258554 0.760871993358246 0.959038446258554
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513

Graft-versus-host disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Kaposi sarcoma-associated herpesvirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Cd200r1 ENSMUSG00000022667 0.189909983271957 0.569729949815872 0.821939806605584 0.821939806605584 0.519662238832756 0.779493358249134
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Ccr1 ENSMUSG00000025804 0.792302154796113 0.792302154796113 0.446414406772984 0.694335669815142 0.462890446543428 0.694335669815142
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Angpt2 ENSMUSG00000031465 0.462119832495408 0.693179748743112 0.877580565516142 0.877580565516142 0.360530245646393 0.693179748743112
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Cd200r3 ENSMUSG00000036172 0.431440919672486 0.647161379508729 0.853761665106688 0.853761665106688 0.154643311183146 0.463929933549438
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Tcf7l1 ENSMUSG00000055799 0.21398017391067 0.641940521732009 0.8776613378323 0.8776613378323 0.556268556406441 0.834402834609662
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Cd200r4 ENSMUSG00000062082 0.216369558113233 0.649108674339699 0.799723885966248 0.962014347558026 0.962014347558026 0.962014347558026
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Apoptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Daxx ENSMUSG00000002307 0.188637664560497 0.493086576099149 0.3287243840661 0.493086576099149 0.687195818423301 0.687195818423301
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Ctsw ENSMUSG00000024910 0.692217950370342 0.692217950370342 0.442083512180914 0.692217950370342 0.546494256518131 0.692217950370342
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Spta1 ENSMUSG00000026532 0.598302167100785 0.66957113976235 0.420408189278753 0.66957113976235 0.66957113976235 0.66957113976235
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Eif2ak3 ENSMUSG00000031668 0.770220192856365 0.770220192856365 0.591262138582003 0.770220192856365 0.588508929767116 0.770220192856365
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Mcl1 ENSMUSG00000038612 0.340745800702317 0.623337332729154 0.415558221819436 0.623337332729154 0.877653407437334 0.877653407437334
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Parp4 ENSMUSG00000054509 0.740022447234291 0.968498594387583 0.968498594387583 0.968498594387583 0.669790149147554 0.968498594387583
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
Csf2rb ENSMUSG00000071713 0.312733987134367 0.371376383337895 0.371376383337895 0.371376383337895 0.152377704632297 0.371376383337895
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Bcl2a1b ENSMUSG00000089929 0.000594932491699785 0.00178479747509936 0.342703540633697 0.514055310950545 0.779235729098386 0.779235729098386

Fanconi anemia pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Fancl ENSMUSG00000004018 0.560801715774823 0.841202573662235 0.548089856730846 0.841202573662235 0.965299516532591 0.965299516532591
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Hes1 ENSMUSG00000022528 0.868336559968714 0.977961087418768 0.074715989943356 0.224147969830068 0.977961087418768 0.977961087418768
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Ube2t ENSMUSG00000026429 0.812371394411998 0.84343594358458 0.84343594358458 0.84343594358458 0.840234771316459 0.84343594358458
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Usp1 ENSMUSG00000028560 0.434058003510885 0.94336484193188 0.687164372043649 0.94336484193188 0.94336484193188 0.94336484193188
Rpa2 ENSMUSG00000028884 0.170429986691734 0.511289960075203 0.971660795072063 0.971660795072063 0.865164540552543 0.971660795072063
C230052I12Rik ENSMUSG00000030493 0.426929509260589 0.542971452620046 0.235190764095948 0.542971452620046 0.542971452620046 0.542971452620046
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Fanca ENSMUSG00000032815 0.893226156598959 0.940210255277229 0.69580320712939 0.940210255277229 0.940210255277229 0.940210255277229
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Fanci ENSMUSG00000039187 0.575451316965023 0.930750441583897 0.930750441583897 0.930750441583897 0.849985040178575 0.930750441583897
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Fancb ENSMUSG00000047757 0.604968877731111 0.946505220715412 0.707611446511957 0.946505220715412 0.946505220715412 0.946505220715412
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967

p53 signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Rrm2 ENSMUSG00000020649 0.252351688728059 0.520099654365892 0.346733102910595 0.520099654365892 0.807659267216762 0.807659267216762
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Shisa5 ENSMUSG00000025647 0.644138439209324 0.82504562183016 0.82504562183016 0.82504562183016 0.509425568925872 0.82504562183016
Cd82 ENSMUSG00000027215 0.731275234467164 0.731275234467164 0.397749236956292 0.731275234467164 0.684297323954655 0.731275234467164
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Ccng2 ENSMUSG00000029385 0.655477499763984 0.952791969458938 0.952791969458938 0.952791969458938 0.588521559014862 0.952791969458938
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Thbs1 ENSMUSG00000040152 0.305682667447087 0.438657653903195 0.249658049586806 0.438657653903195 0.438657653903195 0.438657653903195
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

PD-L1 expression and PD-1 checkpoint pathway in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Batf3 ENSMUSG00000026630 0.0739957285824357 0.221987185747307 0.294670678865549 0.442006018298324 0.655458951166297 0.655458951166297
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Batf ENSMUSG00000034266 0.523970502217033 0.654192846134175 0.654192846134175 0.654192846134175 0.637837611252116 0.654192846134175
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404

Hepatitis C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Rsad2 ENSMUSG00000020641 0.839722509138133 0.839722509138133 0.666481958412304 0.839722509138133 0.748094580276093 0.839722509138133
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Oas1b ENSMUSG00000029605 0.106471808823159 0.261623033496945 0.977955937045276 0.977955937045276 0.17441535566463 0.261623033496945
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Eif2ak3 ENSMUSG00000031668 0.770220192856365 0.770220192856365 0.591262138582003 0.770220192856365 0.588508929767116 0.770220192856365
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Oas3 ENSMUSG00000032661 0.70559622524486 0.70559622524486 0.279847110149665 0.599594349368259 0.399729566245506 0.599594349368259
Oas2 ENSMUSG00000032690 0.590588242763953 0.590588242763953 0.56918471440342 0.590588242763953 0.296490251299649 0.590588242763953
Ifit1 ENSMUSG00000034459 0.755124575574739 0.824491984663596 0.485769632503251 0.824491984663596 0.824491984663596 0.824491984663596
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Oas1a ENSMUSG00000052776 0.624371674343792 0.624371674343792 0.529670161962983 0.624371674343792 0.397448722736607 0.624371674343792
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
Oas1g ENSMUSG00000066861 0.846378700510971 0.877499918788629 0.877499918788629 0.877499918788629 0.624101644356107 0.877499918788629
Gm14446 ENSMUSG00000079339 0.874034542937247 0.990507334532928 0.593712870668459 0.990507334532928 0.990507334532928 0.990507334532928

Type I diabetes mellitus

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Allograft rejection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Malaria

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrb1f ENSMUSG00000030154 0.806041332856845 0.806041332856845 0.764975356318474 0.806041332856845 0.401962557364901 0.806041332856845
Klrb1c ENSMUSG00000030325 0.741739505129971 0.846026054099687 0.846026054099687 0.846026054099687 0.676560133649493 0.846026054099687
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Thbs1 ENSMUSG00000040152 0.305682667447087 0.438657653903195 0.249658049586806 0.438657653903195 0.438657653903195 0.438657653903195
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Gypa ENSMUSG00000051839 0.808072775780216 0.954973991523955 0.145440938196746 0.436322814590237 0.954973991523955 0.954973991523955
Hbb-bs ENSMUSG00000052305 0.177918733884123 0.184202917126453 0.0954928445167644 0.184202917126453 0.184202917126453 0.184202917126453
Hba-a2 ENSMUSG00000069917 0.271210445518381 0.271210445518381 0.0345197208279923 0.103559162483977 0.134707276184888 0.202060914277332
Hba-a1 ENSMUSG00000069919 0.16541301274005 0.16541301274005 0.0258966214889489 0.0776898644668467 0.13793010332663 0.16541301274005
Hbb-bt ENSMUSG00000073940 0.0899400920737443 0.109415412755815 0.0351389280678127 0.105416784203438 0.109415412755815 0.109415412755815
Klrb1b ENSMUSG00000079298 0.553419530301092 0.977815444751151 0.977815444751151 0.977815444751151 0.917994978035563 0.977815444751151

Lipid and atherosclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Sod2 ENSMUSG00000006818 0.167865820111312 0.503597460333936 0.890122073589913 0.890122073589913 0.886897460326536 0.890122073589913
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Vldlr ENSMUSG00000024924 0.752099286646496 0.752099286646496 0.672554738063565 0.752099286646496 0.649794050064027 0.752099286646496
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Eif2ak3 ENSMUSG00000031668 0.770220192856365 0.770220192856365 0.591262138582003 0.770220192856365 0.588508929767116 0.770220192856365
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918

Platelet activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
P2rx1 ENSMUSG00000020787 0.144555343848704 0.391238114954735 0.317040007326369 0.391238114954735 0.391238114954735 0.391238114954735
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Fermt3 ENSMUSG00000024965 0.464768747400279 0.464768747400279 0.108799156668991 0.326397470006974 0.399385485371262 0.464768747400279
Apbb1ip ENSMUSG00000026786 0.984222718319748 0.984222718319748 0.936980388171146 0.984222718319748 0.582832358879193 0.984222718319748
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Tln1 ENSMUSG00000028465 0.572130411303441 0.65267344990602 0.0915572537081786 0.274671761124536 0.65267344990602 0.65267344990602
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Tbxas1 ENSMUSG00000029925 0.524748688703399 0.524748688703399 0.340068003285111 0.510102004927666 0.297300172193797 0.510102004927666
Gp9 ENSMUSG00000030054 0.00377310954923169 0.0113193286476951 0.619292967855541 0.635911427193935 0.635911427193935 0.635911427193935
Vasp ENSMUSG00000030403 0.162000615468473 0.24300092320271 0.0564412028621741 0.169323608586522 0.755124999321721 0.755124999321721
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Adcy7 ENSMUSG00000031659 0.767088974120291 0.767088974120291 0.402013836510905 0.603020754766358 0.166932517211185 0.500797551633555
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Tbxa2r ENSMUSG00000034881 0.169135942438759 0.253703913658139 0.0934023198373406 0.253703913658139 0.787960310844493 0.787960310844493
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Ptgir ENSMUSG00000043017 0.5876394451455 0.5876394451455 0.542777828024823 0.5876394451455 0.503848822292999 0.5876394451455
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Pla2g4f ENSMUSG00000046971 0.22269812603344 0.334047189050161 0.192701711063534 0.334047189050161 0.356977584784787 0.356977584784787
Ptgs1 ENSMUSG00000047250 0.883897250949253 0.959084088142663 0.959084088142663 0.959084088142663 0.192772876506609 0.578318629519826
Gp5 ENSMUSG00000047953 0.697011545864508 0.81649905272153 0.81649905272153 0.81649905272153 0.719462193986791 0.81649905272153
Orai1 ENSMUSG00000049686 0.767211993950886 0.97796128174822 0.222950645168347 0.668851935505041 0.97796128174822 0.97796128174822
F2rl3 ENSMUSG00000050147 0.566362337529305 0.641022029317539 0.159455585790563 0.478366757371688 0.641022029317539 0.641022029317539
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Tln2 ENSMUSG00000052698 0.821956609663064 0.821956609663064 0.422511538568199 0.821956609663064 0.770169895748685 0.821956609663064
Pla2g4a ENSMUSG00000056220 0.318749008972887 0.616134501396929 0.41075633426462 0.616134501396929 0.649592772559609 0.649592772559609
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626

Human immunodeficiency virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Apobec3 ENSMUSG00000009585 0.180531892111101 0.375700544429707 0.871217529696691 0.871217529696691 0.250467029619805 0.375700544429707
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Samhd1 ENSMUSG00000027639 0.692864727102691 0.692864727102691 0.289189318892068 0.433783978338102 0.288948002238271 0.433783978338102
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Mb21d1 ENSMUSG00000032344 0.779193090513379 0.965307232309759 0.965307232309759 0.965307232309759 0.949535403474954 0.965307232309759
Atr ENSMUSG00000032409 0.692950845540677 0.806647108186518 0.800569639573263 0.806647108186518 0.806647108186518 0.806647108186518
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ap1g2 ENSMUSG00000040701 0.758179783638741 0.993702602974369 0.993702602974369 0.993702602974369 0.880789788914798 0.993702602974369
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Ap1s3 ENSMUSG00000054702 0.797443459083025 0.902615530123121 0.902615530123121 0.902615530123121 0.749079742362857 0.902615530123121
Trim12c ENSMUSG00000057143 0.701345485715404 0.883903557923455 0.883903557923455 0.883903557923455 0.629559368162921 0.883903557923455
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Trim30d ENSMUSG00000057596 0.0425138550745834 0.12754156522375 0.422136074732907 0.422136074732907 0.373206854724776 0.422136074732907
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Trim5 ENSMUSG00000060441 0.522634126398269 0.730474309406902 0.730474309406902 0.730474309406902 0.438650665453044 0.730474309406902
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103

Natural killer cell mediated cytotoxicity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cd244 ENSMUSG00000004709 0.3698459464202 0.693215121579387 0.910885918513433 0.910885918513433 0.462143414386258 0.693215121579387
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Cd48 ENSMUSG00000015355 0.0445981895382173 0.133794568614652 0.400256415285073 0.600384622927609 0.799971413443391 0.799971413443391
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Klrb1c ENSMUSG00000030325 0.741739505129971 0.846026054099687 0.846026054099687 0.846026054099687 0.676560133649493 0.846026054099687
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Shc1 ENSMUSG00000042626 0.524862972514124 0.646974935518976 0.646974935518976 0.646974935518976 0.545711178736166 0.646974935518976
Sh3bp2 ENSMUSG00000054520 0.911974971483818 0.911974971483818 0.828027182852383 0.911974971483818 0.748959640927813 0.911974971483818
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Hcst ENSMUSG00000064109 0.32624149620729 0.489362244310936 0.0836947710900175 0.251084313270052 0.644506547522037 0.644506547522037
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
Ulbp1 ENSMUSG00000079685 0.927302561324852 0.984175870311634 0.984175870311634 0.984175870311634 0.609494135796922 0.984175870311634

Human cytomegalovirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
Nfatc4 ENSMUSG00000023411 0.158449282035252 0.450250215315847 0.834297283734774 0.834297283734774 0.300166810210565 0.450250215315847
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Ccr1 ENSMUSG00000025804 0.792302154796113 0.792302154796113 0.446414406772984 0.694335669815142 0.462890446543428 0.694335669815142
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Adcy7 ENSMUSG00000031659 0.767088974120291 0.767088974120291 0.402013836510905 0.603020754766358 0.166932517211185 0.500797551633555
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Nfatc3 ENSMUSG00000031902 0.984253855551187 0.984253855551187 0.338774399438125 0.984253855551187 0.770181050783598 0.984253855551187
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Mb21d1 ENSMUSG00000032344 0.779193090513379 0.965307232309759 0.965307232309759 0.965307232309759 0.949535403474954 0.965307232309759
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Ptger2 ENSMUSG00000037759 0.312084342690198 0.876915325086974 0.648582934967478 0.876915325086974 0.876915325086974 0.876915325086974
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ptger4 ENSMUSG00000039942 0.7973637312854 0.818770025869451 0.371458771603599 0.818770025869451 0.818770025869451 0.818770025869451
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Akap13 ENSMUSG00000066406 0.669623676240994 0.987398272706954 0.89324541901726 0.987398272706954 0.987398272706954 0.987398272706954
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Spi1 ENSMUSG00000002111 0.305634506771214 0.466583643613941 0.571977206622312 0.571977206622312 0.311055762409294 0.466583643613941
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Gstm7 ENSMUSG00000004035 0.664106645443066 0.664106645443066 0.132127874764734 0.396383624294202 0.378130333431663 0.567195500147495
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Hmox1 ENSMUSG00000005413 0.116243022007852 0.348729066023555 0.996846887643168 0.996846887643168 0.293638017122606 0.440457025683909
Epor ENSMUSG00000006235 0.200812051045155 0.602436153135466 0.524715013860017 0.783204721215732 0.783204721215732 0.783204721215732
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Rassf1 ENSMUSG00000010067 0.509510816423788 0.974812830346075 0.974812830346075 0.974812830346075 0.722386321791289 0.974812830346075
Dll1 ENSMUSG00000014773 0.818909718008407 0.974810364509103 0.974810364509103 0.974810364509103 0.687150267748492 0.974810364509103
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Stk4 ENSMUSG00000018209 0.469758824613668 0.993700988225418 0.993700988225418 0.993700988225418 0.794437852652208 0.993700988225418
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Fzd6 ENSMUSG00000022297 0.127076160876296 0.381228482628888 0.946506998067888 0.946506998067888 0.382439236106282 0.573658854159423
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Hes1 ENSMUSG00000022528 0.868336559968714 0.977961087418768 0.074715989943356 0.224147969830068 0.977961087418768 0.977961087418768
Runx1 ENSMUSG00000022952 0.00316544057629907 0.00949632172889721 0.730543719478186 0.730543719478186 0.71873522241951 0.730543719478186
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Pim1 ENSMUSG00000024014 0.342577071367136 0.779577200677213 0.519718133784809 0.779577200677213 0.791320347428075 0.791320347428075
Axin1 ENSMUSG00000024182 0.710497138987201 0.710497138987201 0.61319830297105 0.710497138987201 0.6160148140933 0.710497138987201
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Rassf5 ENSMUSG00000026430 0.684298491773043 0.865219472454728 0.865219472454728 0.865219472454728 0.441037520361291 0.865219472454728
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Jag1 ENSMUSG00000027276 0.550571792775973 0.791283986332569 0.791283986332569 0.791283986332569 0.142624433303508 0.427873299910523
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Bmp2 ENSMUSG00000027358 0.9464752056284 0.984253378994499 0.785268259291587 0.984253378994499 0.984253378994499 0.984253378994499
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Notch2 ENSMUSG00000027878 0.602224868763748 0.734239205174763 0.734239205174763 0.734239205174763 0.285634488186016 0.734239205174763
Tpm3 ENSMUSG00000027940 0.751858290585775 0.751858290585775 0.566286819289201 0.751858290585775 0.417787969509144 0.751858290585775
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Rasgrp4 ENSMUSG00000030589 0.758174681524356 0.758174681524356 0.328684317944978 0.493026476917467 0.165609570465666 0.493026476917467
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Vegfc ENSMUSG00000031520 0.0190679710695843 0.057203913208753 0.146941623747318 0.220412435620977 0.946508644048411 0.946508644048411
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Adcy7 ENSMUSG00000031659 0.767088974120291 0.767088974120291 0.402013836510905 0.603020754766358 0.166932517211185 0.500797551633555
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Lpar2 ENSMUSG00000031861 0.773215987029165 0.788237953096477 0.788237953096477 0.788237953096477 0.553366694936434 0.788237953096477
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Ets1 ENSMUSG00000032035 0.309545240517341 0.346738289862591 0.135212858047756 0.346738289862591 0.346738289862591 0.346738289862591
Gsta4 ENSMUSG00000032348 0.464825211569246 0.707653761788645 0.707653761788645 0.707653761788645 0.687166523939935 0.707653761788645
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Fgf1 ENSMUSG00000036585 0.902618830496872 0.902618830496872 0.561592058005832 0.902618830496872 0.649800330986248 0.902618830496872
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Ptger2 ENSMUSG00000037759 0.312084342690198 0.876915325086974 0.648582934967478 0.876915325086974 0.876915325086974 0.876915325086974
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ptger4 ENSMUSG00000039942 0.7973637312854 0.818770025869451 0.371458771603599 0.818770025869451 0.818770025869451 0.818770025869451
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Il7 ENSMUSG00000040329 0.707498587171359 0.707498587171359 0.602106908115829 0.707498587171359 0.464688969874476 0.707498587171359
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
F2rl3 ENSMUSG00000050147 0.566362337529305 0.641022029317539 0.159455585790563 0.478366757371688 0.641022029317539 0.641022029317539
Tcf7l1 ENSMUSG00000055799 0.21398017391067 0.641940521732009 0.8776613378323 0.8776613378323 0.556268556406441 0.834402834609662
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Gstm1 ENSMUSG00000058135 0.601934731844216 0.689889107510266 0.264684096239972 0.689889107510266 0.689889107510266 0.689889107510266
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513
Lpar5 ENSMUSG00000067714 0.641045819579599 0.82190381758844 0.82190381758844 0.82190381758844 0.476448890686564 0.82190381758844
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
Peg12 ENSMUSG00000070526 0.206630434689915 0.619891304069745 0.530552447985934 0.795828671978901 0.84338134784472 0.84338134784472
Rasgrp3 ENSMUSG00000071042 0.874424809318059 0.874424809318059 0.322933193689276 0.484399790533914 0.316821651693806 0.484399790533914
Csf2rb ENSMUSG00000071713 0.312733987134367 0.371376383337895 0.371376383337895 0.371376383337895 0.152377704632297 0.371376383337895
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Txnrd2 ENSMUSG00000075704 0.0415258802025371 0.0622888203038057 0.000229470574554867 0.000688411723664599 0.398880390467181 0.398880390467181

Viral carcinogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rel ENSMUSG00000020275 0.160937039825879 0.482811119477636 0.380189373880499 0.570284060820748 0.626118865045573 0.626118865045573
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Sp100 ENSMUSG00000026222 0.684228399751986 0.746182300580058 0.746182300580058 0.746182300580058 0.506940699407348 0.746182300580058
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Gtf2a2 ENSMUSG00000033543 0.591199025129356 0.621633440166777 0.621633440166777 0.621633440166777 0.426999601237835 0.621633440166777
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hdac10 ENSMUSG00000062906 0.0438411444736475 0.131523433420942 0.315215322517597 0.315215322517597 0.187244659337631 0.280866989006447
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103

Rheumatoid arthritis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Ctla4 ENSMUSG00000026011 0.754397185072788 0.987229400844189 0.929833477154719 0.987229400844189 0.987229400844189 0.987229400844189
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376
Tnfsf13 ENSMUSG00000089669 0.313250552160584 0.469875828240876 0.962219754077531 0.962219754077531 0.201092493304847 0.469875828240876

JAK-STAT signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Epor ENSMUSG00000006235 0.200812051045155 0.602436153135466 0.524715013860017 0.783204721215732 0.783204721215732 0.783204721215732
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Osmr ENSMUSG00000022146 0.000156058548173884 0.000468175644521653 0.852793209229563 0.852793209229563 0.313326543521735 0.469989815282602
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Il10rb ENSMUSG00000022969 0.943367411266725 0.943367411266725 0.264557137865817 0.79367141359745 0.641278990481585 0.943367411266725
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Pim1 ENSMUSG00000024014 0.342577071367136 0.779577200677213 0.519718133784809 0.779577200677213 0.791320347428075 0.791320347428075
Tslp ENSMUSG00000024379 0.132548241130065 0.397644723390196 0.449777273641288 0.449777273641288 0.352429033437292 0.449777273641288
Ptpn2 ENSMUSG00000024539 0.298364682060503 0.469750527970165 0.391161952011083 0.469750527970165 0.469750527970165 0.469750527970165
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Mcl1 ENSMUSG00000038612 0.340745800702317 0.623337332729154 0.415558221819436 0.623337332729154 0.877653407437334 0.877653407437334
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
Il7 ENSMUSG00000040329 0.707498587171359 0.707498587171359 0.602106908115829 0.707498587171359 0.464688969874476 0.707498587171359
Socs4 ENSMUSG00000048379 0.150362992223028 0.451088976669083 0.831190915312916 0.831190915312916 0.806675810880775 0.831190915312916
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Lepr ENSMUSG00000057722 0.785250416494332 0.785250416494332 0.632786044186941 0.785250416494332 0.261059672298358 0.783179016895075
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
Csf2rb ENSMUSG00000071713 0.312733987134367 0.371376383337895 0.371376383337895 0.371376383337895 0.152377704632297 0.371376383337895
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159

Cell adhesion molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Icosl ENSMUSG00000000732 0.943338320115267 0.943338320115267 0.501935949796012 0.752903924694018 0.230396936429296 0.691190809287889
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
4632428N05Rik ENSMUSG00000020101 0.731240976580737 0.731240976580737 0.346804575203656 0.520206862805484 0.244804505901735 0.520206862805484
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Cd6 ENSMUSG00000024670 0.286026676143659 0.800129658974304 0.800129658974304 0.800129658974304 0.650621487774155 0.800129658974304
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Ctla4 ENSMUSG00000026011 0.754397185072788 0.987229400844189 0.929833477154719 0.987229400844189 0.987229400844189 0.987229400844189
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Sell ENSMUSG00000026581 0.325711266406808 0.847954390669855 0.847954390669855 0.847954390669855 0.608245770963389 0.847954390669855
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Siglec1 ENSMUSG00000027322 0.512701772691446 0.512701772691446 0.384441826986635 0.512701772691446 0.508669442731413 0.512701772691446
Cd2 ENSMUSG00000027863 0.278580689866421 0.741358334683917 0.494238889789278 0.741358334683917 0.742752676431872 0.742752676431872
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Cd22 ENSMUSG00000030577 0.71744671119612 0.85594787258356 0.745822501096633 0.85594787258356 0.85594787258356 0.85594787258356
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Cd226 ENSMUSG00000034028 0.663834392035331 0.740718745538522 0.432564981581081 0.740718745538522 0.740718745538522 0.740718745538522
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Itga9 ENSMUSG00000039115 0.270766588561651 0.406149882842477 0.239851940546128 0.406149882842477 0.713155486817429 0.713155486817429
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Selplg ENSMUSG00000048163 0.0393579701360576 0.118073910408173 0.231740417612258 0.231740417612258 0.117965481907395 0.176948222861092
Spn ENSMUSG00000051457 0.35270298305213 0.544408777119859 0.362939184746573 0.544408777119859 0.958879309278034 0.958879309278034
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Base excision repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Fen1 ENSMUSG00000024742 0.552732828858029 0.703990940968637 0.397683779546578 0.703990940968637 0.703990940968637 0.703990940968637
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Pole3 ENSMUSG00000028394 0.849538701892552 0.849538701892552 0.504347928862361 0.756521893293541 0.294023477972154 0.756521893293541
Mutyh ENSMUSG00000028687 0.574867504158502 0.77019634576434 0.77019634576434 0.77019634576434 0.664040896456067 0.77019634576434
Ogg1 ENSMUSG00000030271 0.0442716123757612 0.132814837127284 0.438688139246743 0.658032208870115 0.734226035946159 0.734226035946159
Neil1 ENSMUSG00000032298 0.552851047579205 0.829276571368808 0.388947726176355 0.829276571368808 0.830863465675073 0.830863465675073
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Neil3 ENSMUSG00000039396 0.993650763435805 0.993650763435805 0.943342252092692 0.993650763435805 0.908172903048363 0.993650763435805
Parp4 ENSMUSG00000054509 0.740022447234291 0.968498594387583 0.968498594387583 0.968498594387583 0.669790149147554 0.968498594387583
Lig1 ENSMUSG00000056394 0.85895180926901 0.85895180926901 0.203706628058387 0.611119884175162 0.713400622584613 0.85895180926901
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456

Pertussis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Irf1 ENSMUSG00000018899 0.326707294677525 0.490060942016288 0.761181164989444 0.761181164989444 0.273095744558522 0.490060942016288
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
C1qa ENSMUSG00000036887 0.249490358808716 0.669529156847566 0.669529156847566 0.669529156847566 0.504118505297814 0.669529156847566
C1qc ENSMUSG00000036896 0.228905135045486 0.452161420954431 0.394469890370354 0.452161420954431 0.452161420954431 0.452161420954431
C1qb ENSMUSG00000036905 0.862026196989381 0.862026196989381 0.742897828900491 0.862026196989381 0.527367937516455 0.862026196989381
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Irf8 ENSMUSG00000041515 0.806225833459761 0.806225833459761 0.0913086527749267 0.27392595832478 0.564572831923006 0.806225833459761
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311

Phagosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
M6pr ENSMUSG00000007458 0.852829893742734 0.852829893742734 0.540450659442691 0.852829893742734 0.675592104802367 0.852829893742734
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Marco ENSMUSG00000026390 0.228399912886854 0.527627445852534 0.881713068632796 0.881713068632796 0.351751630568356 0.527627445852534
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Coro1a ENSMUSG00000030707 0.355037537295033 0.561593589035712 0.561593589035712 0.561593589035712 0.47460318326064 0.561593589035712
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Cd209a ENSMUSG00000031494 0.889824441586438 0.889824441586438 0.635039927675588 0.889824441586438 0.821751695010895 0.889824441586438
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Colec12 ENSMUSG00000036103 0.474574317971101 0.474574317971101 0.408832437002503 0.474574317971101 0.448095170534725 0.474574317971101
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Thbs1 ENSMUSG00000040152 0.305682667447087 0.438657653903195 0.249658049586806 0.438657653903195 0.438657653903195 0.438657653903195
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
5430435G22Rik ENSMUSG00000052688 0.672220230242972 0.672220230242972 0.585511608286338 0.672220230242972 0.447587437260909 0.672220230242972
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Fcgr3 ENSMUSG00000059498 0.0780468839549562 0.234140651864869 0.65551682010443 0.65551682010443 0.212449878518021 0.318674817777032
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
Cd209b ENSMUSG00000065987 0.624893371661887 0.624893371661887 0.609047269065152 0.624893371661887 0.44145132683442 0.624893371661887
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Sec61g ENSMUSG00000078974 0.0666197309250759 0.0999295963876138 0.0309582439386061 0.0928747318158182 0.280191939922263 0.280191939922263
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Viral myocarditis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Cd55 ENSMUSG00000026399 0.60500208339292 0.794461398740089 0.794461398740089 0.794461398740089 0.649785541067507 0.794461398740089
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Chagas disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Gna15 ENSMUSG00000034792 0.461976700843078 0.461976700843078 0.203672627663993 0.30550894149599 0.0462529880702313 0.138758964210694
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
C1qa ENSMUSG00000036887 0.249490358808716 0.669529156847566 0.669529156847566 0.669529156847566 0.504118505297814 0.669529156847566
C1qc ENSMUSG00000036896 0.228905135045486 0.452161420954431 0.394469890370354 0.452161420954431 0.452161420954431 0.452161420954431
C1qb ENSMUSG00000036905 0.862026196989381 0.862026196989381 0.742897828900491 0.862026196989381 0.527367937516455 0.862026196989381
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311

TNF signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Irf1 ENSMUSG00000018899 0.326707294677525 0.490060942016288 0.761181164989444 0.761181164989444 0.273095744558522 0.490060942016288
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Il18r1 ENSMUSG00000026070 0.376172574512653 0.430234124010001 0.430234124010001 0.430234124010001 0.362899627265156 0.430234124010001
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Jag1 ENSMUSG00000027276 0.550571792775973 0.791283986332569 0.791283986332569 0.791283986332569 0.142624433303508 0.427873299910523
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Vegfc ENSMUSG00000031520 0.0190679710695843 0.057203913208753 0.146941623747318 0.220412435620977 0.946508644048411 0.946508644048411
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Junb ENSMUSG00000052837 0.0850774851972727 0.255232455591818 0.788387337290141 0.930807110778034 0.930807110778034 0.930807110778034
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Gm5431 ENSMUSG00000058163 0.374841759123406 0.66420573597063 0.66420573597063 0.66420573597063 0.473926098188413 0.66420573597063
Ifi47 ENSMUSG00000078920 0.509472223704512 0.763685495197748 0.763685495197748 0.763685495197748 0.339933648623244 0.763685495197748

Salmonella infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
M6pr ENSMUSG00000007458 0.852829893742734 0.852829893742734 0.540450659442691 0.852829893742734 0.675592104802367 0.852829893742734
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Fhod1 ENSMUSG00000014778 0.21545686491862 0.646370594755861 0.583058826038355 0.797467638019357 0.797467638019357 0.797467638019357
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cyth4 ENSMUSG00000018008 0.937069338678331 0.937069338678331 0.346827854235173 0.52024178135276 0.0965395073093738 0.289618521928121
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Rhoh ENSMUSG00000029204 0.559248188445637 0.838499133667078 0.838499133667078 0.838499133667078 0.793261255914589 0.838499133667078
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Flna ENSMUSG00000031328 0.812768584424391 0.812768584424391 0.615990120361259 0.812768584424391 0.564120147031627 0.812768584424391
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Plekhm1 ENSMUSG00000034247 0.791393080958356 0.962198994939697 0.946455945034697 0.962198994939697 0.962198994939697 0.962198994939697
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Nlrc4 ENSMUSG00000039193 0.858843988828162 0.9747287565996 0.9747287565996 0.9747287565996 0.539701382478747 0.9747287565996
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Arf6 ENSMUSG00000044147 0.58028691959072 0.9811078280034 0.812759716016395 0.9811078280034 0.9811078280034 0.9811078280034
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
5430435G22Rik ENSMUSG00000052688 0.672220230242972 0.672220230242972 0.585511608286338 0.672220230242972 0.447587437260909 0.672220230242972
Tcf7l1 ENSMUSG00000055799 0.21398017391067 0.641940521732009 0.8776613378323 0.8776613378323 0.556268556406441 0.834402834609662
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Naip2 ENSMUSG00000078945 0.0213468735252908 0.0640406205758724 0.824782352446474 0.824782352446474 0.362974420100341 0.544461630150511
Dynlt1f ENSMUSG00000095677 0.257945480483416 0.773836441450247 0.98425720956738 0.98425720956738 0.661229284453844 0.98425720956738
Dynlt1b ENSMUSG00000096255 0.292852511124036 0.810691676773085 0.965374357523301 0.965374357523301 0.540461117848723 0.810691676773085

Transcriptional misregulation in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Spi1 ENSMUSG00000002111 0.305634506771214 0.466583643613941 0.571977206622312 0.571977206622312 0.311055762409294 0.466583643613941
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Pax5 ENSMUSG00000014030 0.0186093555017439 0.0558280665052318 0.204974322565396 0.307461483848093 0.657838226196952 0.657838226196952
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Fli1 ENSMUSG00000016087 0.281533067394888 0.621208579826964 0.558671138553342 0.621208579826964 0.621208579826964 0.621208579826964
Wt1 ENSMUSG00000016458 0.881764456507293 0.881764456507293 0.83460992794956 0.881764456507293 0.644882068069256 0.881764456507293
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Meis1 ENSMUSG00000020160 0.713523796453799 0.965370076266478 0.927666733981428 0.965370076266478 0.965370076266478 0.965370076266478
Tcf3 ENSMUSG00000020167 0.2872265148422 0.861679544526601 0.764186055773375 0.940200872927201 0.940200872927201 0.940200872927201
Rel ENSMUSG00000020275 0.160937039825879 0.482811119477636 0.380189373880499 0.570284060820748 0.626118865045573 0.626118865045573
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Bcl6 ENSMUSG00000022508 0.251275770950635 0.448072971367178 0.344684344249955 0.448072971367178 0.448072971367178 0.448072971367178
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Runx1 ENSMUSG00000022952 0.00316544057629907 0.00949632172889721 0.730543719478186 0.730543719478186 0.71873522241951 0.730543719478186
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Hhex ENSMUSG00000024986 0.37311721658255 0.776083015425508 0.776083015425508 0.776083015425508 0.646877767622209 0.776083015425508
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Elk4 ENSMUSG00000026436 0.350873510216543 0.644116080964996 0.59667410332771 0.644116080964996 0.644116080964996 0.644116080964996
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Klf3 ENSMUSG00000029178 0.292882808397935 0.651065403872935 0.890132278233511 0.890132278233511 0.434043602581957 0.651065403872935
Aff1 ENSMUSG00000029313 0.338752757923278 0.855924916252705 0.855924916252705 0.855924916252705 0.828121644467447 0.855924916252705
Etv6 ENSMUSG00000030199 0.522215962255415 0.725321893076126 0.725321893076126 0.725321893076126 0.588545938940134 0.725321893076126
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Lmo2 ENSMUSG00000032698 0.433970192533923 0.433970192533923 0.169427628688144 0.27104776367791 0.180698509118606 0.27104776367791
Lyl1 ENSMUSG00000034041 0.858794049082795 0.858794049082795 0.161643424896113 0.242465137344169 0.0399454444666218 0.119836333399866
Bmp2k ENSMUSG00000034663 0.722371873352399 0.880782060207865 0.602241665387811 0.880782060207865 0.880782060207865 0.880782060207865
Nfkbiz ENSMUSG00000035356 0.260611241066268 0.320924989898567 0.320924989898567 0.320924989898567 0.318776376577748 0.320924989898567
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Ss18 ENSMUSG00000037013 0.564241224089586 0.886868393830377 0.977960115694395 0.977960115694395 0.591245595886918 0.886868393830377
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Bcl2a1b ENSMUSG00000089929 0.000594932491699785 0.00178479747509936 0.342703540633697 0.514055310950545 0.779235729098386 0.779235729098386

Fc gamma R-mediated phagocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Fcgr2b ENSMUSG00000026656 0.175555983854996 0.391526067788055 0.26101737852537 0.391526067788055 0.809735523273604 0.809735523273604
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Vasp ENSMUSG00000030403 0.162000615468473 0.24300092320271 0.0564412028621741 0.169323608586522 0.755124999321721 0.755124999321721
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Was ENSMUSG00000031165 0.519172085377981 0.519172085377981 0.358941363716733 0.519172085377981 0.426510036593108 0.519172085377981
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Arf6 ENSMUSG00000044147 0.58028691959072 0.9811078280034 0.812759716016395 0.9811078280034 0.9811078280034 0.9811078280034
Pla2g4f ENSMUSG00000046971 0.22269812603344 0.334047189050161 0.192701711063534 0.334047189050161 0.356977584784787 0.356977584784787
Pla2g4a ENSMUSG00000056220 0.318749008972887 0.616134501396929 0.41075633426462 0.616134501396929 0.649592772559609 0.649592772559609
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Sphk1 ENSMUSG00000061878 0.298016874176902 0.447307795578438 0.298205197052292 0.447307795578438 0.99683985061631 0.99683985061631

Asthma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Necroptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Alox15 ENSMUSG00000018924 0.756258229905085 0.756258229905085 0.439210535680098 0.658815803520147 0.0601629085578724 0.180488725673617
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Zbp1 ENSMUSG00000027514 0.865080865029008 0.865080865029008 0.510714288705774 0.865080865029008 0.637230397483361 0.865080865029008
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Tlr3 ENSMUSG00000031639 0.692984940559031 0.692984940559031 0.522288685484488 0.692984940559031 0.527463024029268 0.692984940559031
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Stat2 ENSMUSG00000040033 0.767185708491536 0.767185708491536 0.74615451241542 0.767185708491536 0.532615179746066 0.767185708491536
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Pla2g4f ENSMUSG00000046971 0.22269812603344 0.334047189050161 0.192701711063534 0.334047189050161 0.356977584784787 0.356977584784787
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Pla2g4a ENSMUSG00000056220 0.318749008972887 0.616134501396929 0.41075633426462 0.616134501396929 0.649592772559609 0.649592772559609
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Stat4 ENSMUSG00000062939 0.987223080284513 0.987223080284513 0.88916482417469 0.987223080284513 0.97762855816652 0.987223080284513
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Slc25a31 ENSMUSG00000069041 0.249872594936304 0.374808892404456 0.92373913611752 0.92373913611752 0.211084213111213 0.374808892404456

Autoimmune thyroid disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Ctla4 ENSMUSG00000026011 0.754397185072788 0.987229400844189 0.929833477154719 0.987229400844189 0.987229400844189 0.987229400844189
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
H2-Aa ENSMUSG00000036594 0.550976874406558 0.826465311609837 0.987402747493102 0.987402747493102 0.436253920197472 0.826465311609837
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
H2-DMa ENSMUSG00000037649 0.739942273539472 0.739942273539472 0.601681814157293 0.739942273539472 0.377417790772438 0.739942273539472
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Tg ENSMUSG00000053469 0.96194533743746 0.96194533743746 0.879743250346888 0.96194533743746 0.808037166825792 0.96194533743746
H2-T24 ENSMUSG00000053835 0.164448591019353 0.493345773058058 0.734188031325531 0.734188031325531 0.422521195041888 0.633781792562832
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Eb1 ENSMUSG00000060586 0.273275776173659 0.382317930384212 0.21838835806241 0.382317930384212 0.382317930384212 0.382317930384212
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
C920025E04Rik ENSMUSG00000073405 0.652396537186621 0.652396537186621 0.319188158636376 0.652396537186621 0.570547019426464 0.652396537186621
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-D1 ENSMUSG00000073411 0.758170521099853 0.758170521099853 0.556195666251068 0.758170521099853 0.438688958953417 0.758170521099853
H2-Ab1 ENSMUSG00000073421 0.415607508424008 0.511880442894492 0.243053316392729 0.511880442894492 0.511880442894492 0.511880442894492
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
H2-DMb1 ENSMUSG00000079547 0.640418827601112 0.640418827601112 0.330608761420796 0.524191393087376 0.349460928724918 0.524191393087376

Legionellosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Hbs1l ENSMUSG00000019977 0.0393057443052295 0.0589586164578442 0.00476572158201247 0.0142971647460374 0.987398533245141 0.987398533245141
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Nlrc4 ENSMUSG00000039193 0.858843988828162 0.9747287565996 0.9747287565996 0.9747287565996 0.539701382478747 0.9747287565996
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Bnip3 ENSMUSG00000078566 0.171911548008357 0.257867322012535 0.110865621689032 0.257867322012535 0.971665255098185 0.971665255098185
Naip2 ENSMUSG00000078945 0.0213468735252908 0.0640406205758724 0.824782352446474 0.824782352446474 0.362974420100341 0.544461630150511

Spliceosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0166694610077386 0.0500083830232158 0.924437275664023 0.924437275664023 0.593783146350941 0.890674719526412
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Snrpb2 ENSMUSG00000008333 0.111876468464953 0.316247284683075 0.21083152312205 0.316247284683075 0.943361205125621 0.943361205125621
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Ccdc12 ENSMUSG00000019659 0.000187501011726525 0.000562503035179576 0.154727115830997 0.232090673746495 0.261274252918596 0.261274252918596
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Tra2b ENSMUSG00000022858 0.088046202952005 0.220666314363082 0.147110876242054 0.220666314363082 0.553621638058049 0.553621638058049
Ppil1 ENSMUSG00000024007 0.118153024895013 0.177229537342519 0.0989269831413781 0.177229537342519 0.874514514061034 0.874514514061034
Snrpc ENSMUSG00000024217 0.399452602234174 0.599178903351261 0.0791729691353165 0.237518907405949 0.766960921682776 0.766960921682776
Dhx16 ENSMUSG00000024422 0.615736992388526 0.615736992388526 0.371097173014268 0.615736992388526 0.44503429182454 0.615736992388526
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Prpf38b ENSMUSG00000027881 0.511989425014589 0.767984137521884 0.352938695468856 0.767984137521884 0.785310343182661 0.785310343182661
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Syf2 ENSMUSG00000028821 0.566883581832035 0.599423435811525 0.303812450234357 0.599423435811525 0.599423435811525 0.599423435811525
Dhx15 ENSMUSG00000029169 0.241578490989996 0.664042271025446 0.652630589639779 0.664042271025446 0.664042271025446 0.664042271025446
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Magohb ENSMUSG00000030188 0.566919045282966 0.749181861069296 0.749181861069296 0.749181861069296 0.499386153452259 0.749181861069296
Lsm6 ENSMUSG00000031683 0.880785442527832 0.896377748432791 0.896377748432791 0.896377748432791 0.728324574258797 0.896377748432791
Lsm4 ENSMUSG00000031848 0.15485119766526 0.23227679649789 0.0303907198543735 0.0911721595631204 0.949642869292636 0.949642869292636
Rp9 ENSMUSG00000032239 0.15498309048215 0.431076321308275 0.287384214205517 0.431076321308275 0.687173376606437 0.687173376606437
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Bud31 ENSMUSG00000038722 0.981109110172814 0.981109110172814 0.438719695410828 0.981109110172814 0.890135118446842 0.981109110172814
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Pcbp1 ENSMUSG00000051695 0.858995742172042 0.858995742172042 0.214016382460339 0.642049147381016 0.734151382873831 0.858995742172042
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Hnrnpm ENSMUSG00000059208 0.933937833575713 0.933937833575713 0.504472793220546 0.933937833575713 0.641274816047717 0.933937833575713
Alyref2 ENSMUSG00000060244 0.785338673845993 0.785338673845993 0.55618687816958 0.785338673845993 0.484387469286486 0.785338673845993
Ppih ENSMUSG00000060288 0.840461784423724 0.859025942688151 0.499420841868875 0.859025942688151 0.859025942688151 0.859025942688151
Prpf40a ENSMUSG00000061136 0.0246204871401498 0.0738614614204495 0.0850034502408037 0.127505175361206 0.824987758959212 0.824987758959212
Phf5a ENSMUSG00000061360 0.298149104107644 0.464734610518925 0.338644411753536 0.464734610518925 0.464734610518925 0.464734610518925
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Lsm5 ENSMUSG00000091625 0.877663587885737 0.877663587885737 0.443282927701248 0.689824377044141 0.459882918029427 0.689824377044141

RNA polymerase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Twistnb ENSMUSG00000020561 0.340750181790478 0.511125272685717 0.169426094457558 0.508278283372674 0.86831174199068 0.86831174199068
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Polr3c ENSMUSG00000028099 0.716446378602089 0.716446378602089 0.669791711571956 0.716446378602089 0.550773488885218 0.716446378602089
Polr1e ENSMUSG00000028318 0.649762019419188 0.852822858033419 0.535227950200136 0.852822858033419 0.852822858033419 0.852822858033419
Polr1d ENSMUSG00000029642 0.0848494993214706 0.127274248982206 0.00917440138128852 0.0275232041438656 0.968510527168435 0.968510527168435
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Polr3b ENSMUSG00000034453 0.788393174127829 0.92140590417822 0.92140590417822 0.92140590417822 0.846654855910342 0.92140590417822
Polr3g ENSMUSG00000035834 0.0641125140282136 0.192337542084641 0.84973061480391 0.84973061480391 0.767089226979462 0.84973061480391
Znrd1 ENSMUSG00000036315 0.0821378908948957 0.246413672684687 0.203887954519348 0.305831931779022 0.32102217702293 0.32102217702293
Polr2j ENSMUSG00000039771 0.413383794173433 0.420123664574307 0.420123664574307 0.420123664574307 0.399918959294222 0.420123664574307
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Polr1c ENSMUSG00000067148 0.519748758068391 0.63849341200239 0.594003694054131 0.63849341200239 0.63849341200239 0.63849341200239

Small cell lung cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Traf5 ENSMUSG00000026637 0.108250822546159 0.324752467638476 0.815864471801022 0.815864471801022 0.227383829299021 0.341075743948532
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

Pancreatic cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

Chronic myeloid leukemia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Runx1 ENSMUSG00000022952 0.00316544057629907 0.00949632172889721 0.730543719478186 0.730543719478186 0.71873522241951 0.730543719478186
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Shc1 ENSMUSG00000042626 0.524862972514124 0.646974935518976 0.646974935518976 0.646974935518976 0.545711178736166 0.646974935518976
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

Neutrophil extracellular trap formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Padi4 ENSMUSG00000025330 0.471481275994036 0.707221913991053 0.772772354431051 0.772772354431051 0.441768037354117 0.707221913991053
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Hat1 ENSMUSG00000027018 0.474100980183443 0.711151470275164 0.225974435063051 0.677923305189154 0.821768100096105 0.821768100096105
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Fpr1 ENSMUSG00000045551 0.482505456036403 0.961596937566084 0.763297093452785 0.961596937566084 0.961596937566084 0.961596937566084
Selplg ENSMUSG00000048163 0.0393579701360576 0.118073910408173 0.231740417612258 0.231740417612258 0.117965481907395 0.176948222861092
C5ar1 ENSMUSG00000049130 2.12809609905041e-05 6.38428829715122e-05 0.430872871373441 0.646309307060162 0.675020900274284 0.675020900274284
Fpr2 ENSMUSG00000052270 0.422001304935369 0.940160893469069 0.940160893469069 0.940160893469069 0.937022766115294 0.940160893469069
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hdac10 ENSMUSG00000062906 0.0438411444736475 0.131523433420942 0.315215322517597 0.315215322517597 0.187244659337631 0.280866989006447
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Slc25a31 ENSMUSG00000069041 0.249872594936304 0.374808892404456 0.92373913611752 0.92373913611752 0.211084213111213 0.374808892404456
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355

Nucleotide excision repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Pole3 ENSMUSG00000028394 0.849538701892552 0.849538701892552 0.504347928862361 0.756521893293541 0.294023477972154 0.756521893293541
Rpa2 ENSMUSG00000028884 0.170429986691734 0.511289960075203 0.971660795072063 0.971660795072063 0.865164540552543 0.971660795072063
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Lig1 ENSMUSG00000056394 0.85895180926901 0.85895180926901 0.203706628058387 0.611119884175162 0.713400622584613 0.85895180926901

AGE-RAGE signaling pathway in diabetic complications

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Pim1 ENSMUSG00000024014 0.342577071367136 0.779577200677213 0.519718133784809 0.779577200677213 0.791320347428075 0.791320347428075
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Stat1 ENSMUSG00000026104 0.698545450978186 0.698545450978186 0.0884407687510751 0.265322306253225 0.232025872891464 0.348038809337197
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Vegfc ENSMUSG00000031520 0.0190679710695843 0.057203913208753 0.146941623747318 0.220412435620977 0.946508644048411 0.946508644048411
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Nfatc1 ENSMUSG00000033016 0.625707875710881 0.868040366954868 0.668614198165107 0.868040366954868 0.868040366954868 0.868040366954868
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055

Acute myeloid leukemia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Spi1 ENSMUSG00000002111 0.305634506771214 0.466583643613941 0.571977206622312 0.571977206622312 0.311055762409294 0.466583643613941
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Runx1 ENSMUSG00000022952 0.00316544057629907 0.00949632172889721 0.730543719478186 0.730543719478186 0.71873522241951 0.730543719478186
Pim1 ENSMUSG00000024014 0.342577071367136 0.779577200677213 0.519718133784809 0.779577200677213 0.791320347428075 0.791320347428075
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tcf7l1 ENSMUSG00000055799 0.21398017391067 0.641940521732009 0.8776613378323 0.8776613378323 0.556268556406441 0.834402834609662
Bcl2a1b ENSMUSG00000089929 0.000594932491699785 0.00178479747509936 0.342703540633697 0.514055310950545 0.779235729098386 0.779235729098386

RIG-I-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Dhx58 ENSMUSG00000017830 0.927667394535469 0.927667394535469 0.536848566865724 0.805272850298586 0.3942803693994 0.805272850298586
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Map3k1 ENSMUSG00000021754 0.959038446258554 0.959038446258554 0.797459645757472 0.959038446258554 0.760871993358246 0.959038446258554
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Traf6 ENSMUSG00000027164 0.761175630559763 0.886990742855323 0.886990742855323 0.886990742855323 0.491749557609223 0.886990742855323
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162

Leukocyte transendothelial migration

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Rassf5 ENSMUSG00000026430 0.684298491773043 0.865219472454728 0.865219472454728 0.865219472454728 0.441037520361291 0.865219472454728
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Rhoh ENSMUSG00000029204 0.559248188445637 0.838499133667078 0.838499133667078 0.838499133667078 0.793261255914589 0.838499133667078
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Vasp ENSMUSG00000030403 0.162000615468473 0.24300092320271 0.0564412028621741 0.169323608586522 0.755124999321721 0.755124999321721
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Msn ENSMUSG00000031207 0.632857647799575 0.632857647799575 0.342756368819007 0.535626944752326 0.357084629834884 0.535626944752326
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Txk ENSMUSG00000054892 0.926341396843506 0.99679920942412 0.99679920942412 0.99679920942412 0.759118382235511 0.99679920942412
Sipa1 ENSMUSG00000056917 0.459903265625102 0.459903265625102 0.0106747451626843 0.0320242354880529 0.24151754084928 0.362276311273919
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918

Proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Pomp ENSMUSG00000029649 0.267682605125045 0.647162037425679 0.431441358283786 0.647162037425679 0.821906793038077 0.821906793038077
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Psmb9 ENSMUSG00000096727 0.380178594109845 0.506104425433568 0.506104425433568 0.506104425433568 0.461276285942858 0.506104425433568

African trypanosomiasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il12a ENSMUSG00000027776 0.45676315464126 1 0.874116228610269 1 1 1
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
Plcb2 ENSMUSG00000040061 0.44521519077814 0.44521519077814 0.386246748088761 0.44521519077814 0.42456512642353 0.44521519077814
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Hbb-bs ENSMUSG00000052305 0.177918733884123 0.184202917126453 0.0954928445167644 0.184202917126453 0.184202917126453 0.184202917126453
Hba-a2 ENSMUSG00000069917 0.271210445518381 0.271210445518381 0.0345197208279923 0.103559162483977 0.134707276184888 0.202060914277332
Hba-a1 ENSMUSG00000069919 0.16541301274005 0.16541301274005 0.0258966214889489 0.0776898644668467 0.13793010332663 0.16541301274005
Hbb-bt ENSMUSG00000073940 0.0899400920737443 0.109415412755815 0.0351389280678127 0.105416784203438 0.109415412755815 0.109415412755815

Colorectal cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Axin1 ENSMUSG00000024182 0.710497138987201 0.710497138987201 0.61319830297105 0.710497138987201 0.6160148140933 0.710497138987201
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Tcf7l1 ENSMUSG00000055799 0.21398017391067 0.641940521732009 0.8776613378323 0.8776613378323 0.556268556406441 0.834402834609662
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

PI3K-Akt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Epor ENSMUSG00000006235 0.200812051045155 0.602436153135466 0.524715013860017 0.783204721215732 0.783204721215732 0.783204721215732
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Myb ENSMUSG00000019982 0.955852363735568 0.955852363735568 0.696065987935615 0.955852363735568 0.920722748727486 0.955852363735568
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Osmr ENSMUSG00000022146 0.000156058548173884 0.000468175644521653 0.852793209229563 0.852793209229563 0.313326543521735 0.469989815282602
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Pik3ap1 ENSMUSG00000025017 0.99369399236377 0.99369399236377 0.899461146927869 0.99369399236377 0.754761678074681 0.99369399236377
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Sgk3 ENSMUSG00000025915 0.803582643875881 0.803582643875881 0.701794378846207 0.803582643875881 0.782261770081503 0.803582643875881
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Tnn ENSMUSG00000026725 0.293645237560948 0.58596191541457 0.58596191541457 0.58596191541457 0.51342894560672 0.58596191541457
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Pkn3 ENSMUSG00000026785 0.731289689848808 0.731289689848808 0.388975707406934 0.583463561110401 0.271563078222944 0.583463561110401
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Angpt4 ENSMUSG00000027460 0.544928255830945 0.817392383746417 0.0488335445269766 0.14650063358093 0.961933231226296 0.961933231226296
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Crtc2 ENSMUSG00000027936 0.905737557312377 0.959079998306599 0.462420433804495 0.959079998306599 0.959079998306599 0.959079998306599
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Tlr2 ENSMUSG00000027995 0.116386884490949 0.349160653472847 0.743004805880922 0.743004805880922 0.646649022741581 0.743004805880922
Them4 ENSMUSG00000028145 0.153778717005039 0.461336151015118 0.610465737405268 0.915698606107901 0.940224030723688 0.940224030723688
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Jak1 ENSMUSG00000028530 0.399823967153365 0.5095002102442 0.5095002102442 0.5095002102442 0.438529305859294 0.5095002102442
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Mtcp1 ENSMUSG00000031200 0.195544445872924 0.195544445872924 0.137282942634416 0.195544445872924 0.162075867472725 0.195544445872924
Il2rg ENSMUSG00000031304 0.968510309179116 0.968510309179116 0.397558301156116 0.596337451734174 0.38018665230656 0.596337451734174
Angpt2 ENSMUSG00000031465 0.462119832495408 0.693179748743112 0.877580565516142 0.877580565516142 0.360530245646393 0.693179748743112
Vegfc ENSMUSG00000031520 0.0190679710695843 0.057203913208753 0.146941623747318 0.220412435620977 0.946508644048411 0.946508644048411
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Lpar2 ENSMUSG00000031861 0.773215987029165 0.788237953096477 0.788237953096477 0.788237953096477 0.553366694936434 0.788237953096477
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Fgf1 ENSMUSG00000036585 0.902618830496872 0.902618830496872 0.561592058005832 0.902618830496872 0.649800330986248 0.902618830496872
Mcl1 ENSMUSG00000038612 0.340745800702317 0.623337332729154 0.415558221819436 0.623337332729154 0.877653407437334 0.877653407437334
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Itga9 ENSMUSG00000039115 0.270766588561651 0.406149882842477 0.239851940546128 0.406149882842477 0.713155486817429 0.713155486817429
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Thbs1 ENSMUSG00000040152 0.305682667447087 0.438657653903195 0.249658049586806 0.438657653903195 0.438657653903195 0.438657653903195
Il7 ENSMUSG00000040329 0.707498587171359 0.707498587171359 0.602106908115829 0.707498587171359 0.464688969874476 0.707498587171359
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Lpar5 ENSMUSG00000067714 0.641045819579599 0.82190381758844 0.82190381758844 0.82190381758844 0.476448890686564 0.82190381758844
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Il3ra ENSMUSG00000068758 0.076654970415938 0.114982455623907 0.00916064911644905 0.0274819473493471 0.797523380421786 0.797523380421786
Ppp2r3d ENSMUSG00000093803 0.370384669250765 0.418312411039641 0.418312411039641 0.418312411039641 0.272916566756265 0.418312411039641

FoxO signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Sod2 ENSMUSG00000006818 0.167865820111312 0.503597460333936 0.890122073589913 0.890122073589913 0.886897460326536 0.890122073589913
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Stk4 ENSMUSG00000018209 0.469758824613668 0.993700988225418 0.993700988225418 0.993700988225418 0.794437852652208 0.993700988225418
Sirt1 ENSMUSG00000020063 0.791414478789436 0.915141605502986 0.831202801623218 0.915141605502986 0.915141605502986 0.915141605502986
Bcl6 ENSMUSG00000022508 0.251275770950635 0.448072971367178 0.344684344249955 0.448072971367178 0.448072971367178 0.448072971367178
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Sgk3 ENSMUSG00000025915 0.803582643875881 0.803582643875881 0.701794378846207 0.803582643875881 0.782261770081503 0.803582643875881
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Ccng2 ENSMUSG00000029385 0.655477499763984 0.952791969458938 0.952791969458938 0.952791969458938 0.588521559014862 0.952791969458938
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
S1pr4 ENSMUSG00000044199 0.0362266857477643 0.0543400286216464 0.00461372364151424 0.0138411709245427 0.36261893230264 0.36261893230264
Irs3 ENSMUSG00000047182 0.305091021018665 0.713470371219655 0.62414632100472 0.713470371219655 0.713470371219655 0.713470371219655
Klf2 ENSMUSG00000055148 0.148090361765012 0.222135542647519 0.143599156929182 0.222135542647519 0.974795475385509 0.974795475385509
Bnip3 ENSMUSG00000078566 0.171911548008357 0.257867322012535 0.110865621689032 0.257867322012535 0.971665255098185 0.971665255098185

Platinum drug resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Gstm7 ENSMUSG00000004035 0.664106645443066 0.664106645443066 0.132127874764734 0.396383624294202 0.378130333431663 0.567195500147495
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Top2a ENSMUSG00000020914 0.0508286730390646 0.152486019117194 0.615481542799229 0.615481542799229 0.590633647308629 0.615481542799229
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Birc3 ENSMUSG00000032000 0.858940839133887 0.858940839133887 0.519720514844346 0.779580772266519 0.415297960132149 0.779580772266519
Gsta4 ENSMUSG00000032348 0.464825211569246 0.707653761788645 0.707653761788645 0.707653761788645 0.687166523939935 0.707653761788645
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Gstm1 ENSMUSG00000058135 0.601934731844216 0.689889107510266 0.264684096239972 0.689889107510266 0.689889107510266 0.689889107510266
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

Adipocytokine signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Jak2 ENSMUSG00000024789 0.506957424770003 0.791420305143382 0.791420305143382 0.791420305143382 0.558932859041533 0.791420305143382
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Ppargc1a ENSMUSG00000029167 0.251040194282025 0.376560291423037 0.138019430324944 0.376560291423037 0.933918678174427 0.933918678174427
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Ikbkb ENSMUSG00000031537 0.582564575885453 0.837127159562762 0.837127159562762 0.837127159562762 0.746130056761131 0.837127159562762
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Irs3 ENSMUSG00000047182 0.305091021018665 0.713470371219655 0.62414632100472 0.713470371219655 0.713470371219655 0.713470371219655
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Lepr ENSMUSG00000057722 0.785250416494332 0.785250416494332 0.632786044186941 0.785250416494332 0.261059672298358 0.783179016895075

Non-small cell lung cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rassf1 ENSMUSG00000010067 0.509510816423788 0.974812830346075 0.974812830346075 0.974812830346075 0.722386321791289 0.974812830346075
Gadd45b ENSMUSG00000015312 0.905752789866191 0.971666463054836 0.441054799311522 0.971666463054836 0.971666463054836 0.971666463054836
Stk4 ENSMUSG00000018209 0.469758824613668 0.993700988225418 0.993700988225418 0.993700988225418 0.794437852652208 0.993700988225418
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Rassf5 ENSMUSG00000026430 0.684298491773043 0.865219472454728 0.865219472454728 0.865219472454728 0.441037520361291 0.865219472454728
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Jak3 ENSMUSG00000031805 0.779094667957401 0.779094667957401 0.547814885253055 0.779094667957401 0.397362372939027 0.779094667957401
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cdkn2a ENSMUSG00000044303 0.366880271871266 0.636868001140711 0.636868001140711 0.636868001140711 0.524026788737038 0.636868001140711
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899

Regulation of actin cytoskeleton

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.779213451475519 0.779213451475519 0.0061360652452141 0.0114428548401941 0.00762856989346274 0.0114428548401941
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Itgae ENSMUSG00000005947 0.602502701522448 0.903754052283671 0.918858148717758 0.918858148717758 0.42458260569218 0.903754052283671
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Spata13 ENSMUSG00000021990 0.457617008485327 0.457617008485327 0.195503537127177 0.457617008485327 0.344797415549297 0.457617008485327
Diap3 ENSMUSG00000022021 0.885266457018139 0.885266457018139 0.377609236104622 0.885266457018139 0.825421081649594 0.885266457018139
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Itga4 ENSMUSG00000027009 0.721563254369896 0.843361896102818 0.843361896102818 0.843361896102818 0.706894446924981 0.843361896102818
Iqgap3 ENSMUSG00000028068 0.243392649306631 0.365088973959946 0.113567006554015 0.340701019662046 0.458382691522496 0.458382691522496
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Pxn ENSMUSG00000029528 0.794446001546544 0.937076072641454 0.69007661748707 0.937076072641454 0.937076072641454 0.937076072641454
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Itgam ENSMUSG00000030786 0.194101874862333 0.208029403982911 0.208029403982911 0.208029403982911 0.17427121103343 0.208029403982911
Itgax ENSMUSG00000030789 0.598006607913018 0.598006607913018 0.332626450570772 0.560169820622968 0.373446547081979 0.560169820622968
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Msn ENSMUSG00000031207 0.632857647799575 0.632857647799575 0.342756368819007 0.535626944752326 0.357084629834884 0.535626944752326
Lpar2 ENSMUSG00000031861 0.773215987029165 0.788237953096477 0.788237953096477 0.788237953096477 0.553366694936434 0.788237953096477
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Fgf1 ENSMUSG00000036585 0.902618830496872 0.902618830496872 0.561592058005832 0.902618830496872 0.649800330986248 0.902618830496872
Ssh2 ENSMUSG00000037926 0.0879124056579512 0.263737216973854 0.60496338972222 0.60496338972222 0.243107796475963 0.364661694713945
Fgd3 ENSMUSG00000037946 0.58570852773432 0.58570852773432 0.427021441598512 0.58570852773432 0.384486959337292 0.58570852773432
Itga9 ENSMUSG00000039115 0.270766588561651 0.406149882842477 0.239851940546128 0.406149882842477 0.713155486817429 0.713155486817429
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Cxcr4 ENSMUSG00000045382 0.365006618590783 0.365006618590783 0.0893750179013944 0.228270732185585 0.152180488123724 0.228270732185585
Tmsb4x ENSMUSG00000049775 0.905754549410294 0.905754549410294 0.770227624847008 0.905754549410294 0.627240621674158 0.905754549410294
Rras2 ENSMUSG00000055723 0.959084193111151 0.959084193111151 0.499434225947636 0.959084193111151 0.893259660574228 0.959084193111151
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Lpar5 ENSMUSG00000067714 0.641045819579599 0.82190381758844 0.82190381758844 0.82190381758844 0.476448890686564 0.82190381758844
Itgad ENSMUSG00000070369 0.139745898256164 0.419237694768493 0.662390156532929 0.662390156532929 0.642902343450638 0.662390156532929

Formation of a pool of free 40S subunits

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

L13a-mediated translational silencing of Ceruloplasmin expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

GTP hydrolysis and joining of the 60S ribosomal subunit

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif5 ENSMUSG00000021282 0.44542141389644 0.737145555579735 0.644120671411172 0.737145555579735 0.737145555579735 0.737145555579735
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Cap-dependent Translation Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif5 ENSMUSG00000021282 0.44542141389644 0.737145555579735 0.644120671411172 0.737145555579735 0.737145555579735 0.737145555579735
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Eif2b1 ENSMUSG00000029388 0.684293286539936 0.955939628783549 0.955939628783549 0.955939628783549 0.380324608439837 0.955939628783549
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Eukaryotic Translation Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif5 ENSMUSG00000021282 0.44542141389644 0.737145555579735 0.644120671411172 0.737145555579735 0.737145555579735 0.737145555579735
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Eif2b1 ENSMUSG00000029388 0.684293286539936 0.955939628783549 0.955939628783549 0.955939628783549 0.380324608439837 0.955939628783549
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Etf1 ENSMUSG00000024360 0.391066270736377 0.586599406104565 0.262773561702372 0.586599406104565 0.746092825693432 0.746092825693432
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

SRP-dependent cotranslational protein targeting to membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Major pathway of rRNA processing in the nucleolus and cytosol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Emg1 ENSMUSG00000004268 0.556279590567972 0.68705095402638 0.68705095402638 0.68705095402638 0.504236000771311 0.68705095402638
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Ltv1 ENSMUSG00000019814 0.445683738470572 0.918198473009061 0.728073781675669 0.918198473009061 0.918198473009061 0.918198473009061
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Pes1 ENSMUSG00000020430 0.141289305163864 0.211933957745797 0.0654095890701058 0.196228767210317 0.399600985557211 0.399600985557211
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ddx52 ENSMUSG00000020677 0.937087073810249 0.937087073810249 0.225982822168226 0.677948466504679 0.846649765782384 0.937087073810249
Ftsj3 ENSMUSG00000020706 0.382461027563758 0.573691541345637 0.173166465008582 0.519499395025745 0.933949336481916 0.933949336481916
Fcf1 ENSMUSG00000021243 0.408875498899118 0.843559329974372 0.843559329974372 0.843559329974372 0.564264783018934 0.843559329974372
Dcaf13 ENSMUSG00000022300 0.791431046203922 0.8528379843735 0.241545693594797 0.724637080784391 0.8528379843735 0.8528379843735
Wdr46 ENSMUSG00000024312 0.167641277283331 0.251461915924996 0.148157355112306 0.251461915924996 0.794214132193644 0.794214132193644
Riok3 ENSMUSG00000024404 0.443311509759737 0.467293812439661 0.361156993786436 0.467293812439661 0.467293812439661 0.467293812439661
Rpp21 ENSMUSG00000024446 0.644062463276438 0.865232874477001 0.865232874477001 0.865232874477001 0.491841097211779 0.865232874477001
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Exosc7 ENSMUSG00000025785 0.0902911688241303 0.270873506472391 0.855938250296372 0.855938250296372 0.484459752742404 0.726689629113606
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Xrn2 ENSMUSG00000027433 0.911964429230093 0.911964429230093 0.545521131758688 0.911964429230093 0.710445458733971 0.911964429230093
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Exosc3 ENSMUSG00000028322 0.800401835468725 0.800401835468725 0.125074818368459 0.375224455105377 0.320609240122114 0.480913860183172
Utp11l ENSMUSG00000028907 0.481557563237796 0.722336344856694 0.207987603863754 0.623962811591262 0.990550109575513 0.990550109575513
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Mphosph10 ENSMUSG00000030521 0.0642305210884326 0.158420702220231 0.105613801480154 0.158420702220231 0.440983168321879 0.440983168321879
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Imp3 ENSMUSG00000032288 0.00856027745168774 0.0256808323550632 0.0590998200304345 0.0886497300456518 0.661066631619884 0.661066631619884
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Wdr36 ENSMUSG00000038299 0.767143496787967 0.767143496787967 0.669803828289417 0.767143496787967 0.49426884234651 0.767143496787967
Tsr1 ENSMUSG00000038335 0.187277035815668 0.280915553723503 0.0630368359728929 0.189110507918679 0.62443460949519 0.62443460949519
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Wdr43 ENSMUSG00000041057 0.356926259807274 0.535389389710911 0.159505144135896 0.478515432407688 0.779105669134706 0.779105669134706
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Gnl3 ENSMUSG00000042354 0.701329747471477 0.701329747471477 0.238122998896618 0.701329747471477 0.596384028891984 0.701329747471477
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Fbl ENSMUSG00000046865 0.206675389008679 0.310013083513019 0.115538025125655 0.310013083513019 0.638415862800893 0.638415862800893
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Exosc5 ENSMUSG00000061286 0.00210892246404626 0.00316338369606939 0.000391908766013276 0.00117572629803983 0.734043951696963 0.734043951696963
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Utp14a ENSMUSG00000063785 0.413305831065245 0.619958746597867 0.143789880724933 0.4313696421748 0.776219422114478 0.776219422114478
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Utp3 ENSMUSG00000070697 0.0864743426068436 0.23419176206827 0.156127841378847 0.23419176206827 0.701715255196257 0.701715255196257
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

rRNA processing in the nucleus and cytosol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Emg1 ENSMUSG00000004268 0.556279590567972 0.68705095402638 0.68705095402638 0.68705095402638 0.504236000771311 0.68705095402638
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Ltv1 ENSMUSG00000019814 0.445683738470572 0.918198473009061 0.728073781675669 0.918198473009061 0.918198473009061 0.918198473009061
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Pes1 ENSMUSG00000020430 0.141289305163864 0.211933957745797 0.0654095890701058 0.196228767210317 0.399600985557211 0.399600985557211
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ddx52 ENSMUSG00000020677 0.937087073810249 0.937087073810249 0.225982822168226 0.677948466504679 0.846649765782384 0.937087073810249
Ftsj3 ENSMUSG00000020706 0.382461027563758 0.573691541345637 0.173166465008582 0.519499395025745 0.933949336481916 0.933949336481916
Fcf1 ENSMUSG00000021243 0.408875498899118 0.843559329974372 0.843559329974372 0.843559329974372 0.564264783018934 0.843559329974372
Dcaf13 ENSMUSG00000022300 0.791431046203922 0.8528379843735 0.241545693594797 0.724637080784391 0.8528379843735 0.8528379843735
Wdr46 ENSMUSG00000024312 0.167641277283331 0.251461915924996 0.148157355112306 0.251461915924996 0.794214132193644 0.794214132193644
Riok3 ENSMUSG00000024404 0.443311509759737 0.467293812439661 0.361156993786436 0.467293812439661 0.467293812439661 0.467293812439661
Rpp21 ENSMUSG00000024446 0.644062463276438 0.865232874477001 0.865232874477001 0.865232874477001 0.491841097211779 0.865232874477001
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Exosc7 ENSMUSG00000025785 0.0902911688241303 0.270873506472391 0.855938250296372 0.855938250296372 0.484459752742404 0.726689629113606
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Xrn2 ENSMUSG00000027433 0.911964429230093 0.911964429230093 0.545521131758688 0.911964429230093 0.710445458733971 0.911964429230093
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Exosc3 ENSMUSG00000028322 0.800401835468725 0.800401835468725 0.125074818368459 0.375224455105377 0.320609240122114 0.480913860183172
Utp11l ENSMUSG00000028907 0.481557563237796 0.722336344856694 0.207987603863754 0.623962811591262 0.990550109575513 0.990550109575513
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Mphosph10 ENSMUSG00000030521 0.0642305210884326 0.158420702220231 0.105613801480154 0.158420702220231 0.440983168321879 0.440983168321879
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Imp3 ENSMUSG00000032288 0.00856027745168774 0.0256808323550632 0.0590998200304345 0.0886497300456518 0.661066631619884 0.661066631619884
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Wdr36 ENSMUSG00000038299 0.767143496787967 0.767143496787967 0.669803828289417 0.767143496787967 0.49426884234651 0.767143496787967
Tsr1 ENSMUSG00000038335 0.187277035815668 0.280915553723503 0.0630368359728929 0.189110507918679 0.62443460949519 0.62443460949519
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Wdr43 ENSMUSG00000041057 0.356926259807274 0.535389389710911 0.159505144135896 0.478515432407688 0.779105669134706 0.779105669134706
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Gnl3 ENSMUSG00000042354 0.701329747471477 0.701329747471477 0.238122998896618 0.701329747471477 0.596384028891984 0.701329747471477
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Fbl ENSMUSG00000046865 0.206675389008679 0.310013083513019 0.115538025125655 0.310013083513019 0.638415862800893 0.638415862800893
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Exosc5 ENSMUSG00000061286 0.00210892246404626 0.00316338369606939 0.000391908766013276 0.00117572629803983 0.734043951696963 0.734043951696963
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Utp14a ENSMUSG00000063785 0.413305831065245 0.619958746597867 0.143789880724933 0.4313696421748 0.776219422114478 0.776219422114478
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Utp3 ENSMUSG00000070697 0.0864743426068436 0.23419176206827 0.156127841378847 0.23419176206827 0.701715255196257 0.701715255196257
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

rRNA processing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Emg1 ENSMUSG00000004268 0.556279590567972 0.68705095402638 0.68705095402638 0.68705095402638 0.504236000771311 0.68705095402638
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Ltv1 ENSMUSG00000019814 0.445683738470572 0.918198473009061 0.728073781675669 0.918198473009061 0.918198473009061 0.918198473009061
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Pes1 ENSMUSG00000020430 0.141289305163864 0.211933957745797 0.0654095890701058 0.196228767210317 0.399600985557211 0.399600985557211
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ddx52 ENSMUSG00000020677 0.937087073810249 0.937087073810249 0.225982822168226 0.677948466504679 0.846649765782384 0.937087073810249
Ftsj3 ENSMUSG00000020706 0.382461027563758 0.573691541345637 0.173166465008582 0.519499395025745 0.933949336481916 0.933949336481916
Fcf1 ENSMUSG00000021243 0.408875498899118 0.843559329974372 0.843559329974372 0.843559329974372 0.564264783018934 0.843559329974372
Dcaf13 ENSMUSG00000022300 0.791431046203922 0.8528379843735 0.241545693594797 0.724637080784391 0.8528379843735 0.8528379843735
Wdr46 ENSMUSG00000024312 0.167641277283331 0.251461915924996 0.148157355112306 0.251461915924996 0.794214132193644 0.794214132193644
Riok3 ENSMUSG00000024404 0.443311509759737 0.467293812439661 0.361156993786436 0.467293812439661 0.467293812439661 0.467293812439661
Rpp21 ENSMUSG00000024446 0.644062463276438 0.865232874477001 0.865232874477001 0.865232874477001 0.491841097211779 0.865232874477001
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Exosc7 ENSMUSG00000025785 0.0902911688241303 0.270873506472391 0.855938250296372 0.855938250296372 0.484459752742404 0.726689629113606
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Xrn2 ENSMUSG00000027433 0.911964429230093 0.911964429230093 0.545521131758688 0.911964429230093 0.710445458733971 0.911964429230093
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Exosc3 ENSMUSG00000028322 0.800401835468725 0.800401835468725 0.125074818368459 0.375224455105377 0.320609240122114 0.480913860183172
Utp11l ENSMUSG00000028907 0.481557563237796 0.722336344856694 0.207987603863754 0.623962811591262 0.990550109575513 0.990550109575513
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Mphosph10 ENSMUSG00000030521 0.0642305210884326 0.158420702220231 0.105613801480154 0.158420702220231 0.440983168321879 0.440983168321879
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Imp3 ENSMUSG00000032288 0.00856027745168774 0.0256808323550632 0.0590998200304345 0.0886497300456518 0.661066631619884 0.661066631619884
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Wdr36 ENSMUSG00000038299 0.767143496787967 0.767143496787967 0.669803828289417 0.767143496787967 0.49426884234651 0.767143496787967
Tsr1 ENSMUSG00000038335 0.187277035815668 0.280915553723503 0.0630368359728929 0.189110507918679 0.62443460949519 0.62443460949519
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Wdr43 ENSMUSG00000041057 0.356926259807274 0.535389389710911 0.159505144135896 0.478515432407688 0.779105669134706 0.779105669134706
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Gnl3 ENSMUSG00000042354 0.701329747471477 0.701329747471477 0.238122998896618 0.701329747471477 0.596384028891984 0.701329747471477
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Fbl ENSMUSG00000046865 0.206675389008679 0.310013083513019 0.115538025125655 0.310013083513019 0.638415862800893 0.638415862800893
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Exosc5 ENSMUSG00000061286 0.00210892246404626 0.00316338369606939 0.000391908766013276 0.00117572629803983 0.734043951696963 0.734043951696963
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Utp14a ENSMUSG00000063785 0.413305831065245 0.619958746597867 0.143789880724933 0.4313696421748 0.776219422114478 0.776219422114478
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Utp3 ENSMUSG00000070697 0.0864743426068436 0.23419176206827 0.156127841378847 0.23419176206827 0.701715255196257 0.701715255196257
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Nonsense-Mediated Decay (NMD)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Etf1 ENSMUSG00000024360 0.391066270736377 0.586599406104565 0.262773561702372 0.586599406104565 0.746092825693432 0.746092825693432
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Pnrc2 ENSMUSG00000028675 0.336735251401969 0.66848741430105 0.4456582762007 0.66848741430105 0.695875598488845 0.695875598488845
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Etf1 ENSMUSG00000024360 0.391066270736377 0.586599406104565 0.262773561702372 0.586599406104565 0.746092825693432 0.746092825693432
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Pnrc2 ENSMUSG00000028675 0.336735251401969 0.66848741430105 0.4456582762007 0.66848741430105 0.695875598488845 0.695875598488845
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Cell Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Ncapg ENSMUSG00000015880 0.199966243903138 0.599898731709415 0.464084132569198 0.696126198853797 0.929712685355956 0.929712685355956
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Hmmr ENSMUSG00000020330 0.50429506937531 0.756442604062965 0.861393672414444 0.861393672414444 0.297159974312533 0.756442604062965
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Esco2 ENSMUSG00000022034 0.170549875965479 0.511649627896437 0.920971568012738 0.920971568012738 0.827941463379142 0.920971568012738
Bora ENSMUSG00000022070 0.440766423606727 0.830081346867545 0.84043263187544 0.84043263187544 0.553387564578363 0.830081346867545
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Nipbl ENSMUSG00000022141 0.161825980309516 0.485477940928549 0.632857913764817 0.80050193145693 0.80050193145693 0.80050193145693
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Mis18a ENSMUSG00000022978 0.981109162888008 0.981109162888008 0.877663099932883 0.981109162888008 0.561547563685078 0.981109162888008
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Esco1 ENSMUSG00000024293 0.937089169618133 1 0.752172083198031 1 1 1
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ppp6r3 ENSMUSG00000024908 0.725285226401555 0.776262387276821 0.43158823472778 0.776262387276821 0.776262387276821 0.776262387276821
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Mastl ENSMUSG00000026779 0.665789497405942 0.714450785405421 0.714450785405421 0.714450785405421 0.374254900720813 0.714450785405421
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Nop10 ENSMUSG00000027133 0.433963194739969 0.585808307031612 0.585808307031612 0.585808307031612 0.251190405158169 0.585808307031612
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Smc2 ENSMUSG00000028312 0.326458439606471 0.773094637907079 0.681263379261997 0.773094637907079 0.773094637907079 0.773094637907079
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Rcc1 ENSMUSG00000028896 0.202319149580428 0.303478724370643 0.143794163220852 0.303478724370643 0.644036312179346 0.644036312179346
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Smc4 ENSMUSG00000034349 0.990552529589583 0.990552529589583 0.476994138443704 0.98313498340287 0.65542332226858 0.98313498340287
Ncaph ENSMUSG00000034906 0.518068092823673 0.609787137767398 0.298355421257038 0.609787137767398 0.609787137767398 0.609787137767398
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Shq1 ENSMUSG00000035378 0.693023808714369 0.693023808714369 0.156197266551862 0.355252234363206 0.236834822908804 0.355252234363206
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Pif1 ENSMUSG00000041064 0.778619210639809 0.942399990559268 0.942399990559268 0.942399990559268 0.808405022155022 0.942399990559268
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Ncapg2 ENSMUSG00000042029 0.477773802439701 0.911844317682146 0.911844317682146 0.911844317682146 0.852290217070967 0.911844317682146
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Mis18bp1 ENSMUSG00000047534 0.451294432983342 0.676941649475013 0.870765548937771 0.870765548937771 0.442816310918232 0.676941649475013
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Oip5 ENSMUSG00000072980 0.879701243029315 0.930060290012718 0.428937086467369 0.930060290012718 0.930060290012718 0.930060290012718
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Cenpw ENSMUSG00000075266 0.582559292756862 0.582559292756862 0.361196903438474 0.582559292756862 0.558383067549043 0.582559292756862
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Crnkl1 ENSMUSG00000001767 0.0166694610077386 0.0500083830232158 0.924437275664023 0.924437275664023 0.593783146350941 0.890674719526412
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Emg1 ENSMUSG00000004268 0.556279590567972 0.68705095402638 0.68705095402638 0.68705095402638 0.504236000771311 0.68705095402638
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Hnrnpa2b1 ENSMUSG00000004980 0.69886671783146 0.725341707588167 0.725341707588167 0.725341707588167 0.644149912834405 0.725341707588167
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Ddx39 ENSMUSG00000005481 0.266365938779284 0.532596299455637 0.369580486206305 0.532596299455637 0.532596299455637 0.532596299455637
Pan2 ENSMUSG00000005682 0.543072263566259 0.818536525704044 0.887007366327093 0.887007366327093 0.54569101713603 0.818536525704044
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Snrpb2 ENSMUSG00000008333 0.111876468464953 0.316247284683075 0.21083152312205 0.316247284683075 0.943361205125621 0.943361205125621
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Apobec3 ENSMUSG00000009585 0.180531892111101 0.375700544429707 0.871217529696691 0.871217529696691 0.250467029619805 0.375700544429707
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Ltv1 ENSMUSG00000019814 0.445683738470572 0.918198473009061 0.728073781675669 0.918198473009061 0.918198473009061 0.918198473009061
Hbs1l ENSMUSG00000019977 0.0393057443052295 0.0589586164578442 0.00476572158201247 0.0142971647460374 0.987398533245141 0.987398533245141
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Ccar1 ENSMUSG00000020074 0.0895399812406913 0.268619943722074 0.271541095954179 0.407311643931269 0.981105971769404 0.981105971769404
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Pes1 ENSMUSG00000020430 0.141289305163864 0.211933957745797 0.0654095890701058 0.196228767210317 0.399600985557211 0.399600985557211
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ddx52 ENSMUSG00000020677 0.937087073810249 0.937087073810249 0.225982822168226 0.677948466504679 0.846649765782384 0.937087073810249
Ftsj3 ENSMUSG00000020706 0.382461027563758 0.573691541345637 0.173166465008582 0.519499395025745 0.933949336481916 0.933949336481916
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Zfp36l1 ENSMUSG00000021127 0.344658554876765 0.56958665186549 0.537830619213933 0.56958665186549 0.56958665186549 0.56958665186549
Fcf1 ENSMUSG00000021243 0.408875498899118 0.843559329974372 0.843559329974372 0.843559329974372 0.564264783018934 0.843559329974372
Snrnp48 ENSMUSG00000021431 0.0602076772577112 0.0998693062174952 0.0665795374783302 0.0998693062174952 0.447787551416281 0.447787551416281
Ppwd1 ENSMUSG00000021713 0.23514399041173 0.352715985617596 0.154977936289727 0.352715985617596 0.993701178881087 0.993701178881087
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Dcaf13 ENSMUSG00000022300 0.791431046203922 0.8528379843735 0.241545693594797 0.724637080784391 0.8528379843735 0.8528379843735
Tra2b ENSMUSG00000022858 0.088046202952005 0.220666314363082 0.147110876242054 0.220666314363082 0.553621638058049 0.553621638058049
Ppil1 ENSMUSG00000024007 0.118153024895013 0.177229537342519 0.0989269831413781 0.177229537342519 0.874514514061034 0.874514514061034
Snrpc ENSMUSG00000024217 0.399452602234174 0.599178903351261 0.0791729691353165 0.237518907405949 0.766960921682776 0.766960921682776
Wdr46 ENSMUSG00000024312 0.167641277283331 0.251461915924996 0.148157355112306 0.251461915924996 0.794214132193644 0.794214132193644
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Etf1 ENSMUSG00000024360 0.391066270736377 0.586599406104565 0.262773561702372 0.586599406104565 0.746092825693432 0.746092825693432
Riok3 ENSMUSG00000024404 0.443311509759737 0.467293812439661 0.361156993786436 0.467293812439661 0.467293812439661 0.467293812439661
Dhx16 ENSMUSG00000024422 0.615736992388526 0.615736992388526 0.371097173014268 0.615736992388526 0.44503429182454 0.615736992388526
Rpp21 ENSMUSG00000024446 0.644062463276438 0.865232874477001 0.865232874477001 0.865232874477001 0.491841097211779 0.865232874477001
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Exosc7 ENSMUSG00000025785 0.0902911688241303 0.270873506472391 0.855938250296372 0.855938250296372 0.484459752742404 0.726689629113606
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Xrn2 ENSMUSG00000027433 0.911964429230093 0.911964429230093 0.545521131758688 0.911964429230093 0.710445458733971 0.911964429230093
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Exosc3 ENSMUSG00000028322 0.800401835468725 0.800401835468725 0.125074818368459 0.375224455105377 0.320609240122114 0.480913860183172
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Pnrc2 ENSMUSG00000028675 0.336735251401969 0.66848741430105 0.4456582762007 0.66848741430105 0.695875598488845 0.695875598488845
Syf2 ENSMUSG00000028821 0.566883581832035 0.599423435811525 0.303812450234357 0.599423435811525 0.599423435811525 0.599423435811525
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Utp11l ENSMUSG00000028907 0.481557563237796 0.722336344856694 0.207987603863754 0.623962811591262 0.990550109575513 0.990550109575513
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Dhx15 ENSMUSG00000029169 0.241578490989996 0.664042271025446 0.652630589639779 0.664042271025446 0.664042271025446 0.664042271025446
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Mphosph10 ENSMUSG00000030521 0.0642305210884326 0.158420702220231 0.105613801480154 0.158420702220231 0.440983168321879 0.440983168321879
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Lsm6 ENSMUSG00000031683 0.880785442527832 0.896377748432791 0.896377748432791 0.896377748432791 0.728324574258797 0.896377748432791
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Dcps ENSMUSG00000032040 0.638348402917678 0.740183803564023 0.740183803564023 0.740183803564023 0.271389643344665 0.740183803564023
Imp3 ENSMUSG00000032288 0.00856027745168774 0.0256808323550632 0.0590998200304345 0.0886497300456518 0.661066631619884 0.661066631619884
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nxt1 ENSMUSG00000036992 0.621284860765305 0.918244168391196 0.918244168391196 0.918244168391196 0.484109198446722 0.918244168391196
Lsm1 ENSMUSG00000037296 0.644146174774956 0.943369588930308 0.834305799736573 0.943369588930308 0.943369588930308 0.943369588930308
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Wdr36 ENSMUSG00000038299 0.767143496787967 0.767143496787967 0.669803828289417 0.767143496787967 0.49426884234651 0.767143496787967
Tsr1 ENSMUSG00000038335 0.187277035815668 0.280915553723503 0.0630368359728929 0.189110507918679 0.62443460949519 0.62443460949519
Bud31 ENSMUSG00000038722 0.981109110172814 0.981109110172814 0.438719695410828 0.981109110172814 0.890135118446842 0.981109110172814
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Apobec1 ENSMUSG00000040613 0.406675979093097 0.710575070695635 0.610514692379546 0.710575070695635 0.710575070695635 0.710575070695635
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Wdr43 ENSMUSG00000041057 0.356926259807274 0.535389389710911 0.159505144135896 0.478515432407688 0.779105669134706 0.779105669134706
Thoc6 ENSMUSG00000041319 0.658299158938436 0.725211259395702 0.725211259395702 0.725211259395702 0.316993797124339 0.725211259395702
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Hnrnpf ENSMUSG00000042079 0.540445724277584 0.86833900748812 0.86833900748812 0.86833900748812 0.627198172521313 0.86833900748812
Gnl3 ENSMUSG00000042354 0.701329747471477 0.701329747471477 0.238122998896618 0.701329747471477 0.596384028891984 0.701329747471477
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Gemin7 ENSMUSG00000044709 0.104798972359443 0.157198458539165 0.014955480050072 0.0448664401502159 0.506989350328231 0.506989350328231
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Fbl ENSMUSG00000046865 0.206675389008679 0.310013083513019 0.115538025125655 0.310013083513019 0.638415862800893 0.638415862800893
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Pcbp1 ENSMUSG00000051695 0.858995742172042 0.858995742172042 0.214016382460339 0.642049147381016 0.734151382873831 0.858995742172042
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Gemin6 ENSMUSG00000055760 0.179494090080546 0.538482270241637 0.918270297644278 0.918270297644278 0.386784067944721 0.580176101917081
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Hnrnpm ENSMUSG00000059208 0.933937833575713 0.933937833575713 0.504472793220546 0.933937833575713 0.641274816047717 0.933937833575713
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gemin2 ENSMUSG00000060121 0.206670646805358 0.620011940416075 0.56675683107152 0.85013524660728 0.927666685647496 0.927666685647496
Ppih ENSMUSG00000060288 0.840461784423724 0.859025942688151 0.499420841868875 0.859025942688151 0.859025942688151 0.859025942688151
Wtap ENSMUSG00000060475 0.646954934744422 0.883895834956624 0.818937001818403 0.883895834956624 0.883895834956624 0.883895834956624
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Prpf40a ENSMUSG00000061136 0.0246204871401498 0.0738614614204495 0.0850034502408037 0.127505175361206 0.824987758959212 0.824987758959212
Exosc5 ENSMUSG00000061286 0.00210892246404626 0.00316338369606939 0.000391908766013276 0.00117572629803983 0.734043951696963 0.734043951696963
Phf5a ENSMUSG00000061360 0.298149104107644 0.464734610518925 0.338644411753536 0.464734610518925 0.464734610518925 0.464734610518925
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Utp14a ENSMUSG00000063785 0.413305831065245 0.619958746597867 0.143789880724933 0.4313696421748 0.776219422114478 0.776219422114478
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Utp3 ENSMUSG00000070697 0.0864743426068436 0.23419176206827 0.156127841378847 0.23419176206827 0.701715255196257 0.701715255196257
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Sarnp ENSMUSG00000078427 0.129072399107977 0.273145551583203 0.182097034388802 0.273145551583203 0.918249374405348 0.918249374405348
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Lsm5 ENSMUSG00000091625 0.877663587885737 0.877663587885737 0.443282927701248 0.689824377044141 0.459882918029427 0.689824377044141
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Cell Cycle Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cell Cycle, Mitotic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Ncapg ENSMUSG00000015880 0.199966243903138 0.599898731709415 0.464084132569198 0.696126198853797 0.929712685355956 0.929712685355956
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Hmmr ENSMUSG00000020330 0.50429506937531 0.756442604062965 0.861393672414444 0.861393672414444 0.297159974312533 0.756442604062965
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Esco2 ENSMUSG00000022034 0.170549875965479 0.511649627896437 0.920971568012738 0.920971568012738 0.827941463379142 0.920971568012738
Bora ENSMUSG00000022070 0.440766423606727 0.830081346867545 0.84043263187544 0.84043263187544 0.553387564578363 0.830081346867545
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Nipbl ENSMUSG00000022141 0.161825980309516 0.485477940928549 0.632857913764817 0.80050193145693 0.80050193145693 0.80050193145693
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Esco1 ENSMUSG00000024293 0.937089169618133 1 0.752172083198031 1 1 1
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Mastl ENSMUSG00000026779 0.665789497405942 0.714450785405421 0.714450785405421 0.714450785405421 0.374254900720813 0.714450785405421
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Smc2 ENSMUSG00000028312 0.326458439606471 0.773094637907079 0.681263379261997 0.773094637907079 0.773094637907079 0.773094637907079
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Rcc1 ENSMUSG00000028896 0.202319149580428 0.303478724370643 0.143794163220852 0.303478724370643 0.644036312179346 0.644036312179346
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Smc4 ENSMUSG00000034349 0.990552529589583 0.990552529589583 0.476994138443704 0.98313498340287 0.65542332226858 0.98313498340287
Ncaph ENSMUSG00000034906 0.518068092823673 0.609787137767398 0.298355421257038 0.609787137767398 0.609787137767398 0.609787137767398
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Ncapg2 ENSMUSG00000042029 0.477773802439701 0.911844317682146 0.911844317682146 0.911844317682146 0.852290217070967 0.911844317682146
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpl13 ENSMUSG00000000740 0.996850587153993 0.996850587153993 0.464865075660738 0.697297613491107 0.332779253787122 0.697297613491107
Oxa1l ENSMUSG00000000959 0.0468714277461918 0.0703071416192876 0.00193542046174619 0.00580626138523857 0.159416263662743 0.159416263662743
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rpl8 ENSMUSG00000003970 0.0275745636077592 0.0827236908232776 0.208032163212704 0.208032163212704 0.143517838812854 0.208032163212704
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rplp1 ENSMUSG00000007892 0.0215016743090749 0.0645050229272247 0.158531926511708 0.163329982617296 0.163329982617296 0.163329982617296
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rpl10 ENSMUSG00000008682 0.0309525028167702 0.0928575084503106 0.393062056922632 0.589593085383948 0.719427275799054 0.719427275799054
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Mrpl52 ENSMUSG00000010406 0.290875774969212 0.436313662453818 0.0901768363730736 0.270530509119221 0.574848513811461 0.574848513811461
Mrps18c ENSMUSG00000016833 0.231923360024569 0.566552888010418 0.613019785832768 0.613019785832768 0.377701925340278 0.566552888010418
Rpl19 ENSMUSG00000017404 0.373837244246229 0.373837244246229 0.301980398149046 0.373837244246229 0.32299440414272 0.373837244246229
Mrpl24 ENSMUSG00000019710 0.98740208621757 0.98740208621757 0.624422605839828 0.936633908759743 0.30573016813831 0.917190504414931
Mtrf1l ENSMUSG00000019774 0.59934439746624 0.722311290237781 0.722311290237781 0.722311290237781 0.467313141352752 0.722311290237781
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif5 ENSMUSG00000021282 0.44542141389644 0.737145555579735 0.644120671411172 0.737145555579735 0.737145555579735 0.737145555579735
Mrpl36 ENSMUSG00000021607 0.0477019199324951 0.0988380481463397 0.0658920320975598 0.0988380481463397 0.160895255336733 0.160895255336733
Mrps30 ENSMUSG00000021731 0.116186868331814 0.174280302497721 3.50876864324292e-06 1.05263059297287e-05 0.558853789206756 0.558853789206756
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Mrpl40 ENSMUSG00000022706 0.46971241809479 0.704568627142185 0.890125768072393 0.890125768072393 0.365395494123814 0.704568627142185
Etf1 ENSMUSG00000024360 0.391066270736377 0.586599406104565 0.262773561702372 0.586599406104565 0.746092825693432 0.746092825693432
Mrpl27 ENSMUSG00000024414 0.0425571614885346 0.127671484465604 0.219850338917394 0.329775508376091 0.621616258032259 0.621616258032259
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Rplp2 ENSMUSG00000025508 0.017509664566223 0.0262644968493345 0.00210713739252588 0.00632141217757763 0.788015462774487 0.788015462774487
Rpl14 ENSMUSG00000025794 0.114567498619277 0.34370249585783 0.441001474885674 0.441001474885674 0.239948070436562 0.359922105654843
Eef1b2 ENSMUSG00000025967 0.133292500690795 0.149120483623807 0.0276879521641886 0.0830638564925659 0.149120483623807 0.149120483623807
Mrrf ENSMUSG00000026887 0.652671782205307 0.933936545288207 0.933936545288207 0.933936545288207 0.319057149509906 0.933936545288207
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rpl22 ENSMUSG00000028936 0.687160167441377 0.97795969744434 0.97795969744434 0.97795969744434 0.386707133384341 0.97795969744434
Eif2b1 ENSMUSG00000029388 0.684293286539936 0.955939628783549 0.955939628783549 0.955939628783549 0.380324608439837 0.955939628783549
Rpl6 ENSMUSG00000029614 0.887016690311831 0.887016690311831 0.212490654132267 0.623236197743925 0.41549079849595 0.623236197743925
Rpl28 ENSMUSG00000030432 0.933863253994816 0.933863253994816 0.462057815901672 0.693086723852507 0.218266637424669 0.654799912274008
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpl4 ENSMUSG00000032399 0.905746127842101 0.993701102198785 0.025753955490136 0.0772618664704081 0.993701102198785 0.993701102198785
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Mrps17 ENSMUSG00000034211 0.596475912834078 0.596475912834078 0.313158093930024 0.469737140895035 0.0938816830072371 0.281645049021711
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Eef2 ENSMUSG00000034994 0.110792657489226 0.110792657489226 0.00841680099579707 0.0252504029873912 0.106479663135253 0.110792657489226
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Trmt112 ENSMUSG00000038812 0.340692030945095 0.523225726006084 0.348817150670722 0.523225726006084 0.713542791014921 0.713542791014921
Rpl12 ENSMUSG00000038900 0.684267423396336 0.815841002601175 0.815841002601175 0.815841002601175 0.41568517276542 0.815841002601175
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rpl22l1 ENSMUSG00000039221 0.0073073724592383 0.0219221173777149 0.0501006348711607 0.0751509523067411 0.532563207644234 0.532563207644234
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rpl37 ENSMUSG00000041841 0.0800609730608408 0.240182919182522 0.78535291682158 0.78535291682158 0.315135959556871 0.472703939335306
Rpl7 ENSMUSG00000043716 0.770200537004265 0.770200537004265 0.722339400734099 0.770200537004265 0.280222201142172 0.770200537004265
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rpl18a ENSMUSG00000045128 0.322856021257891 0.484284031886837 0.519644023265767 0.519644023265767 0.264646963426922 0.484284031886837
Rpl37a ENSMUSG00000046330 0.0429867429568313 0.128960228870494 0.32094419181191 0.342659841414513 0.342659841414513 0.342659841414513
Rpl9 ENSMUSG00000047215 0.0115052648983416 0.0345157946950248 0.254599497461535 0.381899246192303 0.424760335258437 0.424760335258437
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rpl29 ENSMUSG00000048758 0.837384951654192 0.837384951654192 0.222911640115791 0.402066305579235 0.26804420371949 0.402066305579235
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Rpl36al ENSMUSG00000049751 0.4271234689035 0.996851269323452 0.996851269323452 0.996851269323452 0.66697961487493 0.996851269323452
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rpl38 ENSMUSG00000057322 0.16938730515187 0.508161915455611 0.912002925381964 0.912002925381964 0.35285995427217 0.529289931408254
Rpl32 ENSMUSG00000057841 0.391040857988302 0.586561286982453 0.927657113619481 0.927657113619481 0.371548568133645 0.586561286982453
Rpl10-ps3 ENSMUSG00000058443 0.382453728473346 0.573680592710019 0.883873867563681 0.883873867563681 0.346771191841332 0.573680592710019
Rpl23a ENSMUSG00000058546 0.395514122390438 0.704713886185895 0.704713886185895 0.704713886185895 0.486911104367679 0.704713886185895
Rpl30 ENSMUSG00000058600 0.638408206478841 0.638408206478841 0.252908787222485 0.560830020455039 0.373886680303359 0.560830020455039
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Rpl18 ENSMUSG00000059070 0.205215243713527 0.314413270831318 0.734199434422504 0.734199434422504 0.209608847220878 0.314413270831318
Rpl11 ENSMUSG00000059291 0.569614653267365 0.65548376599307 0.264616363895493 0.65548376599307 0.65548376599307 0.65548376599307
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rpl35a ENSMUSG00000060636 0.340758889632326 0.512052429762455 0.436389059396338 0.512052429762455 0.512052429762455 0.512052429762455
Rpl26 ENSMUSG00000060938 0.100592317758955 0.301776953276866 0.840450920022077 0.840450920022077 0.348790261274907 0.52318539191236
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rpl34 ENSMUSG00000062006 0.19138710751315 0.573680592710019 0.722400559919646 0.722400559919646 0.382453728473346 0.573680592710019
Rpl7a ENSMUSG00000062647 0.83732376897707 0.83732376897707 0.428924922780749 0.643387384171123 0.137199269288304 0.411597807864912
Rpl35 ENSMUSG00000062997 0.15145567276796 0.227183509151939 0.106581526075325 0.227183509151939 0.443226976019545 0.443226976019545
Rpl27 ENSMUSG00000063316 0.0780108882099338 0.154707941697513 0.103138627798342 0.154707941697513 0.698776971583886 0.698776971583886
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Aurkaip1 ENSMUSG00000065990 0.0332472574841781 0.0997417724525344 0.417750007732539 0.417750007732539 0.0746832099850594 0.112024814977589
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Rpl23 ENSMUSG00000071415 0.663943788098965 0.663943788098965 0.410525696773089 0.615788545159634 0.384259824618905 0.615788545159634
Rpl13a ENSMUSG00000074129 0.740195972912085 0.740195972912085 0.397677385903034 0.682751343533633 0.455167562355756 0.682751343533633
Rpl36a ENSMUSG00000079435 0.233629417183802 0.450261267893692 0.91824941080754 0.91824941080754 0.300174178595795 0.450261267893692
Rpl39 ENSMUSG00000079641 0.134118087674463 0.338793851107057 0.225862567404704 0.338793851107057 0.467195192747507 0.467195192747507
Flt3l ENSMUSG00000089989 0.962227282886493 0.962227282886493 0.690114137806908 0.962227282886493 0.222930961483326 0.668792884449978
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
RPL24 ENSMUSG00000098274 0.113708602216395 0.341125806649185 0.971662531885784 0.971662531885784 0.543027617228455 0.814541425842683

Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Icosl ENSMUSG00000000732 0.943338320115267 0.943338320115267 0.501935949796012 0.752903924694018 0.230396936429296 0.691190809287889
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Icam4 ENSMUSG00000001014 0.23905517617492 0.717165528524759 0.949568439846291 0.949568439846291 0.641141721440614 0.949568439846291
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Cfp ENSMUSG00000001128 0.943359992701168 0.943359992701168 0.731278783609124 0.943359992701168 0.130993848922794 0.392981546768381
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Il16 ENSMUSG00000001741 0.611930619841571 0.611930619841571 0.395741565598107 0.593612348397161 0.0545775042155176 0.163732512646553
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Ebi3 ENSMUSG00000003206 0.965320343149152 0.965320343149152 0.243627680256872 0.730883040770617 0.794410637753496 0.965320343149152
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Cd79a ENSMUSG00000003379 0.0234760756176181 0.0704282268528543 0.290616414871814 0.435924622307721 0.864931461359157 0.864931461359157
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Ctse ENSMUSG00000004552 0.918856052119456 0.918856052119456 0.251187453998696 0.753562361996087 0.875521104001122 0.918856052119456
Cd33 ENSMUSG00000004609 0.624162076310881 0.896366932455738 0.896366932455738 0.896366932455738 0.103692509204485 0.311077527613454
Cnn2 ENSMUSG00000004665 0.797466088347213 0.797466088347213 0.17440387844591 0.52321163533773 0.460018626332211 0.690027939498316
Man2b1 ENSMUSG00000005142 0.221379456437071 0.332069184655606 0.102898245215032 0.308694735645097 0.537551056261376 0.537551056261376
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Mmp8 ENSMUSG00000005800 0.140889240722767 0.140889240722767 0.0547378998079672 0.140889240722767 0.121339068976499 0.140889240722767
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rnf114 ENSMUSG00000006418 0.0707966072931103 0.120039356593871 0.0800262377292472 0.120039356593871 0.252757817940992 0.252757817940992
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Kif11 ENSMUSG00000012443 0.450940791551811 0.833564413145664 0.632333222901336 0.833564413145664 0.833564413145664 0.833564413145664
1810033B17Rik ENSMUSG00000013974 0.279125935039134 0.4186889025587 0.143641440000628 0.4186889025587 0.98098837440392 0.98098837440392
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Slamf6 ENSMUSG00000015314 0.292349484278281 0.652848914047876 0.641048050919389 0.652848914047876 0.652848914047876 0.652848914047876
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Lta4h ENSMUSG00000015889 0.369628676400689 0.554443014601033 0.26639591509899 0.554443014601033 0.613289709996223 0.613289709996223
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Slpi ENSMUSG00000017002 0.525901896403392 0.788852844605089 0.883846397225027 0.883846397225027 0.377860256367586 0.788852844605089
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Ctsa ENSMUSG00000017760 0.725083813702546 0.725083813702546 0.136195903706912 0.204293855560368 0.0596331974328757 0.178899592298627
Myo1c ENSMUSG00000017774 0.770207197610339 0.770207197610339 0.436310308243349 0.654465462365024 0.249676321659711 0.654465462365024
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Cd68 ENSMUSG00000018774 0.0250381258104656 0.0751143774313969 0.800368254414597 0.800368254414597 0.704532079262302 0.800368254414597
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Dock2 ENSMUSG00000020143 0.158484207163789 0.462690541745841 0.534861803540552 0.534861803540552 0.308460361163894 0.462690541745841
Stk10 ENSMUSG00000020272 0.955905476444009 0.955905476444009 0.319066640368582 0.955905476444009 0.797400615427349 0.955905476444009
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Rnf130 ENSMUSG00000020376 0.779244330734161 0.779244330734161 0.103052317322185 0.309156951966555 0.722347995785867 0.779244330734161
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Trim11 ENSMUSG00000020455 0.481903950518292 0.921385412007054 0.921385412007054 0.921385412007054 0.865239626150503 0.921385412007054
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
P2rx1 ENSMUSG00000020787 0.144555343848704 0.391238114954735 0.317040007326369 0.391238114954735 0.391238114954735 0.391238114954735
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Npc2 ENSMUSG00000021242 0.436350047225227 0.654525070837841 0.809730542202457 0.809730542202457 0.3509080948472 0.654525070837841
Ly86 ENSMUSG00000021423 0.48934816007253 0.734022240108795 0.981104321793152 0.981104321793152 0.303929321183376 0.734022240108795
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Cd180 ENSMUSG00000021624 0.996835241156126 0.996835241156126 0.955927560068442 0.996835241156126 0.990511138945618 0.996835241156126
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Fyb ENSMUSG00000022148 0.0121348140217551 0.0364044420652652 0.68404209569131 0.68404209569131 0.46432641922888 0.68404209569131
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Rnf19a ENSMUSG00000022280 0.553540091056412 0.644077203144885 0.644077203144885 0.644077203144885 0.574913942850289 0.644077203144885
Sla ENSMUSG00000022372 0.138262809626666 0.414788428879997 0.728112347415511 0.946457422296594 0.946457422296594 0.946457422296594
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Mefv ENSMUSG00000022534 0.840840226570052 0.840840226570052 0.747234696137759 0.840840226570052 0.266684635738278 0.800053907214833
Cd96 ENSMUSG00000022657 0.262283600503039 0.496819237597611 0.331212825065074 0.496819237597611 0.632241161299147 0.632241161299147
Snap29 ENSMUSG00000022765 0.130034552150217 0.39010365645065 0.529846820925724 0.779236594112805 0.779236594112805 0.779236594112805
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Racgap1 ENSMUSG00000023015 0.794313006390566 0.794313006390566 0.357059373567292 0.794313006390566 0.758021625116786 0.794313006390566
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Ube2j2 ENSMUSG00000023286 0.44779564108259 0.516937784476093 0.175699016113411 0.516937784476093 0.516937784476093 0.516937784476093
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Clec4n ENSMUSG00000023349 0.66366094094944 0.911880328065958 0.911880328065958 0.911880328065958 0.788291202279061 0.911880328065958
Mmp25 ENSMUSG00000023903 0.392799211859245 0.392799211859245 0.242249676331987 0.363374514497981 0.233873028061978 0.363374514497981
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Kifc5b ENSMUSG00000024301 0.362067247816443 0.981108933046529 0.981108933046529 0.981108933046529 0.849306098448655 0.981108933046529
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Tslp ENSMUSG00000024379 0.132548241130065 0.397644723390196 0.449777273641288 0.449777273641288 0.352429033437292 0.449777273641288
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Ptpn2 ENSMUSG00000024539 0.298364682060503 0.469750527970165 0.391161952011083 0.469750527970165 0.469750527970165 0.469750527970165
Cd74 ENSMUSG00000024610 0.491779704689238 0.643983510924004 0.2731036564511 0.643983510924004 0.643983510924004 0.643983510924004
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Ostf1 ENSMUSG00000024725 0.952786629726858 0.952786629726858 0.672730855832023 0.952786629726858 0.743161159803043 0.952786629726858
Kif20b ENSMUSG00000024795 0.181620741863458 0.429863611386073 0.524623416289839 0.524623416289839 0.286575740924049 0.429863611386073
Aldh3b1 ENSMUSG00000024885 0.675616471945016 0.806688380160056 0.806688380160056 0.806688380160056 0.630045600373785 0.806688380160056
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Pik3ap1 ENSMUSG00000025017 0.99369399236377 0.99369399236377 0.899461146927869 0.99369399236377 0.754761678074681 0.99369399236377
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Pa2g4 ENSMUSG00000025364 0.649781268076141 0.918265286627348 0.319109697057608 0.918265286627348 0.918265286627348 0.918265286627348
Ifitm1 ENSMUSG00000025491 0.846628774219761 0.955920688024455 0.955920688024455 0.955920688024455 0.402092636721738 0.955920688024455
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Pgm2 ENSMUSG00000025791 0.580107345915472 0.794455945027837 0.266172380329822 0.794455945027837 0.794455945027837 0.794455945027837
Hk3 ENSMUSG00000025877 0.476944236414916 0.965351774163959 0.663993304822913 0.965351774163959 0.965351774163959 0.965351774163959
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Il1rl1 ENSMUSG00000026069 0.261767210688227 0.751371986150376 0.751371986150376 0.751371986150376 0.594440646111953 0.751371986150376
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Slc11a1 ENSMUSG00000026177 0.00542095916779017 0.0162628775033705 0.207868305665005 0.207868305665005 0.0574547952608854 0.0861821928913281
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Cd55 ENSMUSG00000026399 0.60500208339292 0.794461398740089 0.794461398740089 0.794461398740089 0.649785541067507 0.794461398740089
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Lcn2 ENSMUSG00000026822 0.254206613494242 0.597762311676581 0.815097344133041 0.815097344133041 0.398508207784387 0.597762311676581
Fcna ENSMUSG00000026938 0.613001224980952 0.78508657962769 0.78508657962769 0.78508657962769 0.658227135226011 0.78508657962769
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Sla2 ENSMUSG00000027636 0.618611624131476 0.766707841294844 0.766707841294844 0.766707841294844 0.731971346679776 0.766707841294844
Ptpn22 ENSMUSG00000027843 0.911431699891067 0.949348855133307 0.655124708730282 0.949348855133307 0.949348855133307 0.949348855133307
S100a11 ENSMUSG00000027907 0.427106192169171 0.640659288253756 0.332800591805441 0.640659288253756 0.649807999096829 0.649807999096829
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Them4 ENSMUSG00000028145 0.153778717005039 0.461336151015118 0.610465737405268 0.915698606107901 0.940224030723688 0.940224030723688
Dapp1 ENSMUSG00000028159 0.921332971189463 0.921332971189463 0.695945259915935 0.921332971189463 0.352619245541218 0.921332971189463
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Tnfsf8 ENSMUSG00000028362 0.572378473457636 0.585516979927963 0.535638996314391 0.585516979927963 0.585516979927963 0.585516979927963
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Rnf19b ENSMUSG00000028793 0.532645053624408 0.798967580436612 0.296517106759042 0.798967580436612 0.818939226902113 0.818939226902113
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Fgr ENSMUSG00000028874 0.815052467550623 0.835991601564856 0.835991601564856 0.835991601564856 0.68832951884056 0.835991601564856
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Tnfrsf9 ENSMUSG00000028965 0.551979116404505 0.849045304877206 0.778404727857629 0.849045304877206 0.849045304877206 0.849045304877206
Plac8 ENSMUSG00000029322 0.743101566724127 0.743101566724127 0.52209179605968 0.743101566724127 0.629965772019568 0.743101566724127
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Herc6 ENSMUSG00000029798 0.612950298138434 0.713439177396024 0.346357654321052 0.713439177396024 0.713439177396024 0.713439177396024
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Lag3 ENSMUSG00000030124 0.0293339755433157 0.0880019266299471 0.468392170911408 0.468392170911408 0.442396426854509 0.468392170911408
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Clec4b1 ENSMUSG00000030147 0.22922165224967 0.51305545899669 0.933532321349815 0.933532321349815 0.34203697266446 0.51305545899669
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Cd27 ENSMUSG00000030336 0.63681419423859 0.855166267900634 0.855166267900634 0.855166267900634 0.426478775983714 0.855166267900634
Lilra6 ENSMUSG00000030427 0.539296770535499 0.539296770535499 0.466255201605349 0.539296770535499 0.0874940183369075 0.262482055010722
Siglecg ENSMUSG00000030468 0.247620943271295 0.742862829813885 0.95802095183943 0.95802095183943 0.941902228360924 0.95802095183943
Siglece ENSMUSG00000030474 0.292191785373393 0.438287678060089 0.285214487265963 0.438287678060089 0.601980510117661 0.601980510117661
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Kif22 ENSMUSG00000030677 0.885416501893169 0.885416501893169 0.531976482183958 0.885416501893169 0.677233817408276 0.885416501893169
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Itgax ENSMUSG00000030789 0.598006607913018 0.598006607913018 0.332626450570772 0.560169820622968 0.373446547081979 0.560169820622968
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Cotl1 ENSMUSG00000031827 0.537587395147477 0.537587395147477 0.305560946064738 0.537587395147477 0.371722801509783 0.537587395147477
Ifi30 ENSMUSG00000031838 0.136196168338928 0.408588505016783 0.362468437705198 0.543702656557797 0.635093801711498 0.635093801711498
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Crtam ENSMUSG00000032021 0.463064186093688 0.618181917795528 0.533674747735192 0.618181917795528 0.618181917795528 0.618181917795528
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Ltf ENSMUSG00000032496 0.407857077827021 0.407857077827021 0.352691902770801 0.407857077827021 0.24312638437072 0.407857077827021
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Lmo7 ENSMUSG00000033060 0.959080527863416 0.959080527863416 0.899497043605159 0.959080527863416 0.880788573559636 0.959080527863416
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Fbxl8 ENSMUSG00000033313 0.479380961112214 0.534495897087936 0.035256707377205 0.105770122131615 0.534495897087936 0.534495897087936
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Cct2 ENSMUSG00000034024 0.491903194177525 0.678469807028642 0.67560413526916 0.678469807028642 0.678469807028642 0.678469807028642
Cd226 ENSMUSG00000034028 0.663834392035331 0.740718745538522 0.432564981581081 0.740718745538522 0.740718745538522 0.740718745538522
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Kif4 ENSMUSG00000034311 0.672008419392125 0.990536313934708 0.990536313934708 0.990536313934708 0.697881022724766 0.990536313934708
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Ube2f ENSMUSG00000034343 0.00440034435439205 0.0132010330631761 0.704568606010613 0.704568606010613 0.4622914721435 0.69343720821525
Gns ENSMUSG00000034707 0.585744743221312 0.585744743221312 0.225846932859948 0.585744743221312 0.529940645351044 0.585744743221312
Eef2 ENSMUSG00000034994 0.110792657489226 0.110792657489226 0.00841680099579707 0.0252504029873912 0.106479663135253 0.110792657489226
Hpse ENSMUSG00000035273 0.834250559137513 0.993695759207487 0.993695759207487 0.993695759207487 0.210578695020539 0.631736085061617
Tnfsf9 ENSMUSG00000035678 0.868119017145407 0.930773105897805 0.930773105897805 0.930773105897805 0.352566427942107 0.930773105897805
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Hmha1 ENSMUSG00000035697 0.172244269892772 0.172244269892772 0.0142213787902949 0.0426641363708846 0.0594695573239394 0.0892043359859091
Dok3 ENSMUSG00000035711 0.868318942543772 0.868318942543772 0.469517568494081 0.704276352741121 0.422301834777126 0.704276352741121
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Kif15 ENSMUSG00000036768 0.443458689078018 0.870799973478293 0.870799973478293 0.870799973478293 0.770537063848605 0.870799973478293
C1qa ENSMUSG00000036887 0.249490358808716 0.669529156847566 0.669529156847566 0.669529156847566 0.504118505297814 0.669529156847566
C1qc ENSMUSG00000036896 0.228905135045486 0.452161420954431 0.394469890370354 0.452161420954431 0.452161420954431 0.452161420954431
C1qb ENSMUSG00000036905 0.862026196989381 0.862026196989381 0.742897828900491 0.862026196989381 0.527367937516455 0.862026196989381
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
Aim2 ENSMUSG00000037860 0.731086205696361 0.871350032640993 0.455273305926355 0.871350032640993 0.871350032640993 0.871350032640993
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Mylip ENSMUSG00000038175 0.548264737903629 0.797480985865397 0.797480985865397 0.797480985865397 0.658216111193869 0.797480985865397
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Txndc5 ENSMUSG00000038991 0.89325623695993 0.89325623695993 0.420178502891541 0.89325623695993 0.632842448827872 0.89325623695993
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Fgl2 ENSMUSG00000039899 0.53004522287058 0.779281632899727 0.604991029214678 0.779281632899727 0.779281632899727 0.779281632899727
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Tbc1d10c ENSMUSG00000040247 0.0489378623710267 0.14681358711308 0.648841705947697 0.865124455501488 0.865124455501488 0.865124455501488
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Arhgap9 ENSMUSG00000040345 0.25440003416661 0.692300745623403 0.609664489496356 0.692300745623403 0.692300745623403 0.692300745623403
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
Cd79b ENSMUSG00000040592 0.00661659993021874 0.0198497997906562 0.461073544589017 0.461073544589017 0.220163789450436 0.330245684175654
Clcf1 ENSMUSG00000040663 0.172236824241387 0.25835523636208 0.987404528198245 0.987404528198245 0.0903124155374292 0.25835523636208
Cd53 ENSMUSG00000040747 0.204230023552655 0.583085861213892 0.568786601077757 0.583085861213892 0.583085861213892 0.583085861213892
Lat2 ENSMUSG00000040751 0.266052463569623 0.79815739070887 0.877496843120831 0.877496843120831 0.837323356678055 0.877496843120831
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Rnf123 ENSMUSG00000041528 0.167767326168535 0.261537021708523 0.174358014472349 0.261537021708523 0.505363156997845 0.505363156997845
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Tnfrsf18 ENSMUSG00000041954 0.565886325135964 0.848829487703946 0.398530238309786 0.848829487703946 0.93922116070972 0.93922116070972
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Sh2b3 ENSMUSG00000042594 0.843477893509635 0.843477893509635 0.47949183846227 0.843477893509635 0.740074482594798 0.843477893509635
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Pde12 ENSMUSG00000043702 0.073424105599251 0.220272316797753 0.962224737253253 0.981105309298905 0.981105309298905 0.981105309298905
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Serpinb1a ENSMUSG00000044734 0.955932521486043 0.955932521486043 0.90574767825056 0.955932521486043 0.629946409608427 0.955932521486043
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Fpr1 ENSMUSG00000045551 0.482505456036403 0.961596937566084 0.763297093452785 0.961596937566084 0.961596937566084 0.961596937566084
Plaur ENSMUSG00000046223 0.031290111184484 0.0938703335534521 0.727998969991539 0.727998969991539 0.724909794670447 0.727998969991539
Pilra ENSMUSG00000046245 0.45967775817636 0.68951663726454 0.849616462733731 0.849616462733731 0.133144627932194 0.399433883796583
Tifa ENSMUSG00000046688 0.797194835803375 0.965346849459665 0.965346849459665 0.965346849459665 0.812399545150088 0.965346849459665
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Fbxo30 ENSMUSG00000047648 0.60646621436897 0.60646621436897 0.0912162139669631 0.273648641900889 0.508493268797473 0.60646621436897
Cd300e ENSMUSG00000048498 0.362308350224987 0.804540447752196 0.857551973977173 0.857551973977173 0.536360298501464 0.804540447752196
Amica1 ENSMUSG00000048534 0.731063619237529 0.766561034920006 0.766561034920006 0.766561034920006 0.736548171939597 0.766561034920006
C5ar1 ENSMUSG00000049130 2.12809609905041e-05 6.38428829715122e-05 0.430872871373441 0.646309307060162 0.675020900274284 0.675020900274284
Trappc1 ENSMUSG00000049299 0.0636197260554133 0.19085917816624 0.569499074646589 0.569499074646589 0.148148319811587 0.22222247971738
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Il31ra ENSMUSG00000050377 0.849572606020411 0.888445216680373 0.888445216680373 0.888445216680373 0.808998783693655 0.888445216680373
Plekho2 ENSMUSG00000050721 0.125908406674103 0.377725220022309 0.661052734917824 0.661052734917824 0.530021902517946 0.661052734917824
Kif18b ENSMUSG00000051378 0.699497905862386 0.89879920473075 0.175784701503063 0.527354104509188 0.89879920473075 0.89879920473075
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Treml4 ENSMUSG00000051682 0.725146410326218 0.961747246857256 0.641947009095968 0.961747246857256 0.961747246857256 0.961747246857256
Pld4 ENSMUSG00000052160 0.00151338949273559 0.00227008423910338 0.00015532135136257 0.00046596405408771 0.00252467839912377 0.00252467839912377
Cd177 ENSMUSG00000052212 0.840260674462718 0.840260674462718 0.698397279822997 0.840260674462718 0.749576335810622 0.840260674462718
Fpr2 ENSMUSG00000052270 0.422001304935369 0.940160893469069 0.940160893469069 0.940160893469069 0.937022766115294 0.940160893469069
Hbb-bs ENSMUSG00000052305 0.177918733884123 0.184202917126453 0.0954928445167644 0.184202917126453 0.184202917126453 0.184202917126453
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
Ap1s3 ENSMUSG00000054702 0.797443459083025 0.902615530123121 0.902615530123121 0.902615530123121 0.749079742362857 0.902615530123121
Txk ENSMUSG00000054892 0.926341396843506 0.99679920942412 0.99679920942412 0.99679920942412 0.759118382235511 0.99679920942412
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Ptafr ENSMUSG00000056529 0.0441827335989428 0.132548200796828 0.593971401895849 0.602122704505769 0.602122704505769 0.602122704505769
Glipr1 ENSMUSG00000056888 0.184671633933133 0.554014901799398 0.880732772529595 0.880732772529595 0.632796650542833 0.880732772529595
Slc44a2 ENSMUSG00000057193 0.209630797175147 0.389429118761442 0.259619412507628 0.389429118761442 0.583072386391489 0.583072386391489
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Unc13d ENSMUSG00000057948 0.340681589288171 0.987403352398658 0.893257208399537 0.987403352398658 0.987403352398658 0.987403352398658
Nfam1 ENSMUSG00000058099 0.871059968930905 0.871059968930905 0.0371031239612186 0.111309371883656 0.141481193731918 0.212221790597878
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Pirb ENSMUSG00000058818 0.332702388332113 0.499053582498169 0.880725310592458 0.880725310592458 0.313012553202442 0.499053582498169
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Ifitm6 ENSMUSG00000059108 0.855701602771772 0.895933675800579 0.353082934651329 0.895933675800579 0.895933675800579 0.895933675800579
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Atp8b4 ENSMUSG00000060131 0.914606757652261 0.914606757652261 0.742671503030267 0.914606757652261 0.326925863650837 0.914606757652261
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Gmfg ENSMUSG00000060791 0.630004717252735 0.749184080834323 0.749184080834323 0.749184080834323 0.445726456417397 0.749184080834323
Prcp ENSMUSG00000061119 0.352837135755494 0.671859704909435 0.806643889978581 0.806643889978581 0.447906469939623 0.671859704909435
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Efcab4b ENSMUSG00000061414 0.736077129430565 0.962120919858673 0.962120919858673 0.962120919858673 0.58373308079493 0.962120919858673
Cd300lb ENSMUSG00000063193 0.0207312822843939 0.0621938468531818 0.570511330654218 0.661128772713596 0.661128772713596 0.661128772713596
Rnf217 ENSMUSG00000063760 0.887020073445203 0.887020073445203 0.527471287724155 0.887020073445203 0.704722342205069 0.887020073445203
Hcst ENSMUSG00000064109 0.32624149620729 0.489362244310936 0.0836947710900175 0.251084313270052 0.644506547522037 0.644506547522037
Rab44 ENSMUSG00000064147 0.240858243998035 0.240858243998035 0.139752249953515 0.215365210573624 0.143576807049083 0.215365210573624
Ano6 ENSMUSG00000064210 0.646693915422459 0.880681105629327 0.658293185525752 0.880681105629327 0.880681105629327 0.880681105629327
Hvcn1 ENSMUSG00000064267 0.521948935143001 0.77308424723638 0.77308424723638 0.77308424723638 0.596377119652557 0.77308424723638
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Cpped1 ENSMUSG00000065979 0.955927933831199 0.955927933831199 0.18468407060505 0.55405221181515 0.54827981290724 0.822419719360861
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Lyz2 ENSMUSG00000069516 0.42459148370476 0.564042324168096 0.320942239145082 0.564042324168096 0.564042324168096 0.564042324168096
Cd300lh ENSMUSG00000069607 0.0654098325668049 0.196229497700415 0.298291561185138 0.298291561185138 0.183357512591348 0.275036268887022
Nlrp1a ENSMUSG00000069830 0.522940617415826 0.784410926123738 0.893200773561383 0.893200773561383 0.35492385366701 0.784410926123738
Rnf213 ENSMUSG00000070327 0.918264013263851 0.918264013263851 0.707465071177749 0.918264013263851 0.388511225347229 0.918264013263851
Lilra5 ENSMUSG00000070873 0.855929610640207 0.855929610640207 0.471740515136299 0.855929610640207 0.840368362498668 0.855929610640207
Il1rl2 ENSMUSG00000070942 0.736254623457522 0.736254623457522 0.715767190861718 0.736254623457522 0.66882612900309 0.736254623457522
Rasgrp3 ENSMUSG00000071042 0.874424809318059 0.874424809318059 0.322933193689276 0.484399790533914 0.316821651693806 0.484399790533914
Treml2 ENSMUSG00000071068 0.00364231313578268 0.010926939407348 0.64490120596842 0.64490120596842 0.404808766825899 0.607213150238849
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Ccnf ENSMUSG00000072082 0.940052121072276 0.940052121072276 0.464909375449865 0.940052121072276 0.924329535381536 0.940052121072276
Ear2 ENSMUSG00000072596 0.216760398415574 0.50672335410396 0.50672335410396 0.50672335410396 0.489114359644712 0.50672335410396
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
Hbb-bt ENSMUSG00000073940 0.0899400920737443 0.109415412755815 0.0351389280678127 0.105416784203438 0.109415412755815 0.109415412755815
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
C5ar2 ENSMUSG00000074361 0.4263099087702 0.6394648631553 0.379598781320832 0.6394648631553 0.770156442663169 0.770156442663169
Gm14548 ENSMUSG00000074417 0.407777464874274 0.534334354372858 0.534334354372858 0.534334354372858 0.473292008332101 0.534334354372858
Sirpb1c ENSMUSG00000074677 0.579356914885657 0.869035372328486 0.283768706558931 0.851306119676793 0.984157520402225 0.984157520402225
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Ighg2c ENSMUSG00000076612 0.548099743416651 0.724696349762504 0.724696349762504 0.724696349762504 0.598008175272639 0.724696349762504
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379
Kifc1 ENSMUSG00000079553 0.345291705320585 0.517937557980878 0.176909636489439 0.517937557980878 0.531472280670156 0.531472280670156
Cd101 ENSMUSG00000086564 0.977724476809487 0.977724476809487 0.610102369589349 0.915153554384024 0.395129040096097 0.915153554384024
Pira2 ENSMUSG00000089942 0.490037291108727 0.735055936663091 0.870817218757294 0.870817218757294 0.390389473033881 0.735055936663091
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Gm20547 ENSMUSG00000092511 0.764375811023646 0.993443816439094 0.0586286027899168 0.175885808369751 0.993443816439094 0.993443816439094
Sirpb1b ENSMUSG00000095028 0.884834703790803 0.910771720569585 0.910771720569585 0.910771720569585 0.402516263798805 0.910771720569585
Dynlt1f ENSMUSG00000095677 0.257945480483416 0.773836441450247 0.98425720956738 0.98425720956738 0.661229284453844 0.98425720956738
Sirpb1a ENSMUSG00000095788 0.206684240616655 0.409326851364192 0.510394876146869 0.510394876146869 0.272884567576128 0.409326851364192
Dynlt1b ENSMUSG00000096255 0.292852511124036 0.810691676773085 0.965374357523301 0.965374357523301 0.540461117848723 0.810691676773085
Tnfsf12 ENSMUSG00000097328 0.561531635206684 0.842297452810027 0.322979008125066 0.842297452810027 0.943358622315216 0.943358622315216

Ribosomal scanning and start codon recognition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif5 ENSMUSG00000021282 0.44542141389644 0.737145555579735 0.644120671411172 0.737145555579735 0.737145555579735 0.737145555579735
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109

Translation initiation complex formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109

Formation of the ternary complex, and subsequently, the 43S complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.0956775314251902 0.139179335010031 0.139179335010031 0.139179335010031 0.112778972412069 0.139179335010031
Rps9 ENSMUSG00000006333 0.0239559524281546 0.0718678572844637 0.0987851647832683 0.118929802325035 0.118929802325035 0.118929802325035
Rps18 ENSMUSG00000008668 0.241521027079093 0.36228154061864 0.815704048101393 0.815704048101393 0.193922772747099 0.36228154061864
Rps15a ENSMUSG00000008683 0.0570463733282924 0.171139119984877 0.445761020813208 0.445761020813208 0.205300340441269 0.307950510661903
Rps25 ENSMUSG00000009927 0.186096552677943 0.558289658033829 0.890099166798287 0.890099166798287 0.462281447985062 0.693422171977593
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Eif2s1 ENSMUSG00000021116 0.00269630905099093 0.0080889271529728 0.0497569574976122 0.0746354362464182 0.886951537083132 0.886951537083132
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Eif3h ENSMUSG00000022312 0.937086029332802 0.937086029332802 0.32880026879389 0.822466010945814 0.548310673963876 0.822466010945814
Eif3e ENSMUSG00000022336 0.652646256141805 0.978969384212707 0.0787361722580506 0.236208516774152 0.990553550651169 0.990553550651169
Rps14 ENSMUSG00000024608 0.0378802178767955 0.113640653630386 0.553550336757181 0.553550336757181 0.271524917140787 0.40728737571118
Eif3a ENSMUSG00000024991 0.150420647537335 0.451261942612006 0.737157154647922 0.737157154647922 0.710522690713282 0.737157154647922
Rps24 ENSMUSG00000025290 0.812786214853958 0.812786214853958 0.233688187796771 0.701064563390313 0.672718939787446 0.812786214853958
Rps26 ENSMUSG00000025362 0.371482578000439 0.371482578000439 0.262812025891712 0.371482578000439 0.120039057568759 0.360117172706278
Eif3m ENSMUSG00000027170 0.477062804651063 0.870577117986006 0.949653290757125 0.949653290757125 0.580384745324004 0.870577117986006
Rps3a1 ENSMUSG00000028081 0.987402018677186 0.987402018677186 0.185654352931983 0.556963058795948 0.377817998011291 0.566726997016937
Rps20 ENSMUSG00000028234 0.0814410221073847 0.244323066322154 0.239656733809077 0.359485100713615 0.564005687295829 0.564005687295829
Eif3i ENSMUSG00000028798 0.116430057908364 0.349290173725092 0.755146210344911 0.755146210344911 0.477026872829435 0.715540309244153
Rps3 ENSMUSG00000030744 0.11831166066201 0.354934981986029 0.7222929915218 0.7222929915218 0.431698769892527 0.647548154838791
Eif3f ENSMUSG00000031029 0.0273650805405177 0.0410476208107765 0.013906444771833 0.0410476208107765 0.962203606347375 0.962203606347375
Rps4x ENSMUSG00000031320 0.211057702461918 0.316586553692878 0.87759510900845 0.87759510900845 0.209434985127561 0.316586553692878
Rpsa ENSMUSG00000032518 0.613003371339774 0.613003371339774 0.269271589284481 0.403907383926722 0.187093347590494 0.403907383926722
Eif3l ENSMUSG00000033047 0.996849231697813 0.996849231697813 0.0856487521151944 0.151738149609569 0.101158766406379 0.151738149609569
Rps29 ENSMUSG00000034892 0.0167503394850504 0.0502510184551511 0.259620107179797 0.389430160769696 0.462501401461119 0.462501401461119
Rps16 ENSMUSG00000037563 0.0689771212306892 0.206931363692068 0.517164665457661 0.517164665457661 0.162004628635077 0.243006942952615
Rps21 ENSMUSG00000039001 0.040983444146504 0.122950332439512 0.496891975896276 0.524829507184653 0.524829507184653 0.524829507184653
Rps19 ENSMUSG00000040952 0.0642683253956291 0.192804976186887 0.56693686044568 0.56693686044568 0.422508163882368 0.56693686044568
Rps2 ENSMUSG00000044533 0.18858802702873 0.282882040543095 0.00270129221116118 0.00810387663348354 0.399944283123881 0.399944283123881
Rps8 ENSMUSG00000047675 0.0221442758176201 0.0664328274528602 0.068361631303008 0.102542446954512 0.206737490147791 0.206737490147791
Rps23 ENSMUSG00000049517 0.602230265011825 0.68139299902623 0.397754730419919 0.68139299902623 0.68139299902623 0.68139299902623
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Rps10 ENSMUSG00000052146 0.491678094632759 0.5534713690829 0.5534713690829 0.5534713690829 0.212503799809356 0.5534713690829
Eif3k ENSMUSG00000053565 0.324868340681523 0.487302511022285 0.68138734765396 0.68138734765396 0.171913379100869 0.487302511022285
Eif3b ENSMUSG00000056076 0.624395031807781 0.764155407143417 0.0390224470510589 0.117067341153177 0.764155407143417 0.764155407143417
Eif4b ENSMUSG00000058655 0.862066935738648 0.862066935738648 0.542893825899625 0.862066935738648 0.669699838119269 0.862066935738648
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rps7 ENSMUSG00000061477 0.918273498392276 0.918273498392276 0.309447838191008 0.675737530937106 0.450491687291404 0.675737530937106
Rps17 ENSMUSG00000061787 0.26810088114265 0.764310111873736 0.940228107548902 0.940228107548902 0.509540074582491 0.764310111873736
Rps15 ENSMUSG00000063457 0.0332860563238009 0.0998581689714028 0.710523957309812 0.710523957309812 0.151488916248577 0.227233374372866
Rps28 ENSMUSG00000067288 0.0313024618753256 0.0939073856259769 0.431584315343972 0.431584315343972 0.230564268673406 0.345846403010109

Cytokine Signaling in Immune system

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Il16 ENSMUSG00000001741 0.611930619841571 0.611930619841571 0.395741565598107 0.593612348397161 0.0545775042155176 0.163732512646553
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Ebi3 ENSMUSG00000003206 0.965320343149152 0.965320343149152 0.243627680256872 0.730883040770617 0.794410637753496 0.965320343149152
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Sla ENSMUSG00000022372 0.138262809626666 0.414788428879997 0.728112347415511 0.946457422296594 0.946457422296594 0.946457422296594
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tslp ENSMUSG00000024379 0.132548241130065 0.397644723390196 0.449777273641288 0.449777273641288 0.352429033437292 0.449777273641288
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Ptpn2 ENSMUSG00000024539 0.298364682060503 0.469750527970165 0.391161952011083 0.469750527970165 0.469750527970165 0.469750527970165
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1rl1 ENSMUSG00000026069 0.261767210688227 0.751371986150376 0.751371986150376 0.751371986150376 0.594440646111953 0.751371986150376
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Sla2 ENSMUSG00000027636 0.618611624131476 0.766707841294844 0.766707841294844 0.766707841294844 0.731971346679776 0.766707841294844
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Tnfsf8 ENSMUSG00000028362 0.572378473457636 0.585516979927963 0.535638996314391 0.585516979927963 0.585516979927963 0.585516979927963
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Tnfrsf9 ENSMUSG00000028965 0.551979116404505 0.849045304877206 0.778404727857629 0.849045304877206 0.849045304877206 0.849045304877206
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Cd27 ENSMUSG00000030336 0.63681419423859 0.855166267900634 0.855166267900634 0.855166267900634 0.426478775983714 0.855166267900634
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Tnfsf9 ENSMUSG00000035678 0.868119017145407 0.930773105897805 0.930773105897805 0.930773105897805 0.352566427942107 0.930773105897805
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Clcf1 ENSMUSG00000040663 0.172236824241387 0.25835523636208 0.987404528198245 0.987404528198245 0.0903124155374292 0.25835523636208
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Tnfrsf18 ENSMUSG00000041954 0.565886325135964 0.848829487703946 0.398530238309786 0.848829487703946 0.93922116070972 0.93922116070972
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Sh2b3 ENSMUSG00000042594 0.843477893509635 0.843477893509635 0.47949183846227 0.843477893509635 0.740074482594798 0.843477893509635
Pde12 ENSMUSG00000043702 0.073424105599251 0.220272316797753 0.962224737253253 0.981105309298905 0.981105309298905 0.981105309298905
Il31ra ENSMUSG00000050377 0.849572606020411 0.888445216680373 0.888445216680373 0.888445216680373 0.808998783693655 0.888445216680373
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Il1rl2 ENSMUSG00000070942 0.736254623457522 0.736254623457522 0.715767190861718 0.736254623457522 0.66882612900309 0.736254623457522
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Tnfsf12 ENSMUSG00000097328 0.561531635206684 0.842297452810027 0.322979008125066 0.842297452810027 0.943358622315216 0.943358622315216

HDR through Homologous Recombination (HRR)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

S Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Esco2 ENSMUSG00000022034 0.170549875965479 0.511649627896437 0.920971568012738 0.920971568012738 0.827941463379142 0.920971568012738
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Esco1 ENSMUSG00000024293 0.937089169618133 1 0.752172083198031 1 1 1
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

DNA Replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

G2/M Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Synthesis of DNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mitotic Metaphase and Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Rcc1 ENSMUSG00000028896 0.202319149580428 0.303478724370643 0.143794163220852 0.303478724370643 0.644036312179346 0.644036312179346
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TCR signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Fyb ENSMUSG00000022148 0.0121348140217551 0.0364044420652652 0.68404209569131 0.68404209569131 0.46432641922888 0.68404209569131
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ptpn22 ENSMUSG00000027843 0.911431699891067 0.949348855133307 0.655124708730282 0.949348855133307 0.949348855133307 0.949348855133307
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Cd101 ENSMUSG00000086564 0.977724476809487 0.977724476809487 0.610102369589349 0.915153554384024 0.395129040096097 0.915153554384024
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mitotic Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Rcc1 ENSMUSG00000028896 0.202319149580428 0.303478724370643 0.143794163220852 0.303478724370643 0.644036312179346 0.644036312179346
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mitotic Prometaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Ncapg ENSMUSG00000015880 0.199966243903138 0.599898731709415 0.464084132569198 0.696126198853797 0.929712685355956 0.929712685355956
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Smc2 ENSMUSG00000028312 0.326458439606471 0.773094637907079 0.681263379261997 0.773094637907079 0.773094637907079 0.773094637907079
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Smc4 ENSMUSG00000034349 0.990552529589583 0.990552529589583 0.476994138443704 0.98313498340287 0.65542332226858 0.98313498340287
Ncaph ENSMUSG00000034906 0.518068092823673 0.609787137767398 0.298355421257038 0.609787137767398 0.609787137767398 0.609787137767398
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

Separation of Sister Chromatids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Amplification of signal from the kinetochores

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

Homology Directed Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Ppp4c ENSMUSG00000030697 0.0592125528199272 0.0888188292298908 0.0405678931068457 0.0888188292298908 0.543076952932224 0.543076952932224
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Tipin ENSMUSG00000032397 0.167415262600935 0.502245787802805 0.596543418981314 0.894815128471971 0.946411756114403 0.946411756114403
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Polq ENSMUSG00000034206 0.757834625288544 0.971659899649896 0.971659899649896 0.971659899649896 0.843274394860513 0.971659899649896
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Timeless ENSMUSG00000039994 0.862002146024331 0.862002146024331 0.44108597923605 0.711344769384679 0.474229846256453 0.711344769384679
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

M Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Ncapg ENSMUSG00000015880 0.199966243903138 0.599898731709415 0.464084132569198 0.696126198853797 0.929712685355956 0.929712685355956
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Nipbl ENSMUSG00000022141 0.161825980309516 0.485477940928549 0.632857913764817 0.80050193145693 0.80050193145693 0.80050193145693
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Mastl ENSMUSG00000026779 0.665789497405942 0.714450785405421 0.714450785405421 0.714450785405421 0.374254900720813 0.714450785405421
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Smc2 ENSMUSG00000028312 0.326458439606471 0.773094637907079 0.681263379261997 0.773094637907079 0.773094637907079 0.773094637907079
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Rcc1 ENSMUSG00000028896 0.202319149580428 0.303478724370643 0.143794163220852 0.303478724370643 0.644036312179346 0.644036312179346
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Smc4 ENSMUSG00000034349 0.990552529589583 0.990552529589583 0.476994138443704 0.98313498340287 0.65542332226858 0.98313498340287
Ncaph ENSMUSG00000034906 0.518068092823673 0.609787137767398 0.298355421257038 0.609787137767398 0.609787137767398 0.609787137767398
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Ncapg2 ENSMUSG00000042029 0.477773802439701 0.911844317682146 0.911844317682146 0.911844317682146 0.852290217070967 0.911844317682146
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Espl1 ENSMUSG00000058290 0.961333587837195 0.961333587837195 0.387649815319914 0.961333587837195 0.724535243631828 0.961333587837195
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

RHO GTPase Effectors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Diap3 ENSMUSG00000022021 0.885266457018139 0.885266457018139 0.377609236104622 0.885266457018139 0.825421081649594 0.885266457018139
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Fmnl3 ENSMUSG00000023008 0.158539230267744 0.39771690707546 0.36330781619577 0.39771690707546 0.39771690707546 0.39771690707546
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Pkn3 ENSMUSG00000026785 0.731289689848808 0.731289689848808 0.388975707406934 0.583463561110401 0.271563078222944 0.583463561110401
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Iqgap3 ENSMUSG00000028068 0.243392649306631 0.365088973959946 0.113567006554015 0.340701019662046 0.458382691522496 0.458382691522496
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Flna ENSMUSG00000031328 0.812768584424391 0.812768584424391 0.615990120361259 0.812768584424391 0.564120147031627 0.812768584424391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Prc1 ENSMUSG00000038943 0.373757452673877 0.628142132046485 0.418761421364323 0.628142132046485 0.712427555029132 0.712427555029132
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Kif14 ENSMUSG00000041498 0.927406634335313 0.927406634335313 0.795430810323814 0.927406634335313 0.8900799978083 0.927406634335313
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115

Innate Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Cfp ENSMUSG00000001128 0.943359992701168 0.943359992701168 0.731278783609124 0.943359992701168 0.130993848922794 0.392981546768381
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cnn2 ENSMUSG00000004665 0.797466088347213 0.797466088347213 0.17440387844591 0.52321163533773 0.460018626332211 0.690027939498316
Man2b1 ENSMUSG00000005142 0.221379456437071 0.332069184655606 0.102898245215032 0.308694735645097 0.537551056261376 0.537551056261376
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Mmp8 ENSMUSG00000005800 0.140889240722767 0.140889240722767 0.0547378998079672 0.140889240722767 0.121339068976499 0.140889240722767
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
1810033B17Rik ENSMUSG00000013974 0.279125935039134 0.4186889025587 0.143641440000628 0.4186889025587 0.98098837440392 0.98098837440392
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Lta4h ENSMUSG00000015889 0.369628676400689 0.554443014601033 0.26639591509899 0.554443014601033 0.613289709996223 0.613289709996223
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Slpi ENSMUSG00000017002 0.525901896403392 0.788852844605089 0.883846397225027 0.883846397225027 0.377860256367586 0.788852844605089
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Ctsa ENSMUSG00000017760 0.725083813702546 0.725083813702546 0.136195903706912 0.204293855560368 0.0596331974328757 0.178899592298627
Myo1c ENSMUSG00000017774 0.770207197610339 0.770207197610339 0.436310308243349 0.654465462365024 0.249676321659711 0.654465462365024
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Cd68 ENSMUSG00000018774 0.0250381258104656 0.0751143774313969 0.800368254414597 0.800368254414597 0.704532079262302 0.800368254414597
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Dock2 ENSMUSG00000020143 0.158484207163789 0.462690541745841 0.534861803540552 0.534861803540552 0.308460361163894 0.462690541745841
Stk10 ENSMUSG00000020272 0.955905476444009 0.955905476444009 0.319066640368582 0.955905476444009 0.797400615427349 0.955905476444009
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
P2rx1 ENSMUSG00000020787 0.144555343848704 0.391238114954735 0.317040007326369 0.391238114954735 0.391238114954735 0.391238114954735
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Npc2 ENSMUSG00000021242 0.436350047225227 0.654525070837841 0.809730542202457 0.809730542202457 0.3509080948472 0.654525070837841
Ly86 ENSMUSG00000021423 0.48934816007253 0.734022240108795 0.981104321793152 0.981104321793152 0.303929321183376 0.734022240108795
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Cd180 ENSMUSG00000021624 0.996835241156126 0.996835241156126 0.955927560068442 0.996835241156126 0.990511138945618 0.996835241156126
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Mefv ENSMUSG00000022534 0.840840226570052 0.840840226570052 0.747234696137759 0.840840226570052 0.266684635738278 0.800053907214833
Snap29 ENSMUSG00000022765 0.130034552150217 0.39010365645065 0.529846820925724 0.779236594112805 0.779236594112805 0.779236594112805
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Clec4n ENSMUSG00000023349 0.66366094094944 0.911880328065958 0.911880328065958 0.911880328065958 0.788291202279061 0.911880328065958
Mmp25 ENSMUSG00000023903 0.392799211859245 0.392799211859245 0.242249676331987 0.363374514497981 0.233873028061978 0.363374514497981
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Ostf1 ENSMUSG00000024725 0.952786629726858 0.952786629726858 0.672730855832023 0.952786629726858 0.743161159803043 0.952786629726858
Aldh3b1 ENSMUSG00000024885 0.675616471945016 0.806688380160056 0.806688380160056 0.806688380160056 0.630045600373785 0.806688380160056
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Pa2g4 ENSMUSG00000025364 0.649781268076141 0.918265286627348 0.319109697057608 0.918265286627348 0.918265286627348 0.918265286627348
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Pgm2 ENSMUSG00000025791 0.580107345915472 0.794455945027837 0.266172380329822 0.794455945027837 0.794455945027837 0.794455945027837
Hk3 ENSMUSG00000025877 0.476944236414916 0.965351774163959 0.663993304822913 0.965351774163959 0.965351774163959 0.965351774163959
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Slc11a1 ENSMUSG00000026177 0.00542095916779017 0.0162628775033705 0.207868305665005 0.207868305665005 0.0574547952608854 0.0861821928913281
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Cd55 ENSMUSG00000026399 0.60500208339292 0.794461398740089 0.794461398740089 0.794461398740089 0.649785541067507 0.794461398740089
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Lcn2 ENSMUSG00000026822 0.254206613494242 0.597762311676581 0.815097344133041 0.815097344133041 0.398508207784387 0.597762311676581
Fcna ENSMUSG00000026938 0.613001224980952 0.78508657962769 0.78508657962769 0.78508657962769 0.658227135226011 0.78508657962769
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
S100a11 ENSMUSG00000027907 0.427106192169171 0.640659288253756 0.332800591805441 0.640659288253756 0.649807999096829 0.649807999096829
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Fgr ENSMUSG00000028874 0.815052467550623 0.835991601564856 0.835991601564856 0.835991601564856 0.68832951884056 0.835991601564856
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Plac8 ENSMUSG00000029322 0.743101566724127 0.743101566724127 0.52209179605968 0.743101566724127 0.629965772019568 0.743101566724127
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Clec4b1 ENSMUSG00000030147 0.22922165224967 0.51305545899669 0.933532321349815 0.933532321349815 0.34203697266446 0.51305545899669
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Lilra6 ENSMUSG00000030427 0.539296770535499 0.539296770535499 0.466255201605349 0.539296770535499 0.0874940183369075 0.262482055010722
Siglecg ENSMUSG00000030468 0.247620943271295 0.742862829813885 0.95802095183943 0.95802095183943 0.941902228360924 0.95802095183943
Siglece ENSMUSG00000030474 0.292191785373393 0.438287678060089 0.285214487265963 0.438287678060089 0.601980510117661 0.601980510117661
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Itgax ENSMUSG00000030789 0.598006607913018 0.598006607913018 0.332626450570772 0.560169820622968 0.373446547081979 0.560169820622968
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Cotl1 ENSMUSG00000031827 0.537587395147477 0.537587395147477 0.305560946064738 0.537587395147477 0.371722801509783 0.537587395147477
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Ltf ENSMUSG00000032496 0.407857077827021 0.407857077827021 0.352691902770801 0.407857077827021 0.24312638437072 0.407857077827021
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Cct2 ENSMUSG00000034024 0.491903194177525 0.678469807028642 0.67560413526916 0.678469807028642 0.678469807028642 0.678469807028642
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Gns ENSMUSG00000034707 0.585744743221312 0.585744743221312 0.225846932859948 0.585744743221312 0.529940645351044 0.585744743221312
Eef2 ENSMUSG00000034994 0.110792657489226 0.110792657489226 0.00841680099579707 0.0252504029873912 0.106479663135253 0.110792657489226
Hpse ENSMUSG00000035273 0.834250559137513 0.993695759207487 0.993695759207487 0.993695759207487 0.210578695020539 0.631736085061617
Hmha1 ENSMUSG00000035697 0.172244269892772 0.172244269892772 0.0142213787902949 0.0426641363708846 0.0594695573239394 0.0892043359859091
Dok3 ENSMUSG00000035711 0.868318942543772 0.868318942543772 0.469517568494081 0.704276352741121 0.422301834777126 0.704276352741121
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
C1qa ENSMUSG00000036887 0.249490358808716 0.669529156847566 0.669529156847566 0.669529156847566 0.504118505297814 0.669529156847566
C1qc ENSMUSG00000036896 0.228905135045486 0.452161420954431 0.394469890370354 0.452161420954431 0.452161420954431 0.452161420954431
C1qb ENSMUSG00000036905 0.862026196989381 0.862026196989381 0.742897828900491 0.862026196989381 0.527367937516455 0.862026196989381
Aim2 ENSMUSG00000037860 0.731086205696361 0.871350032640993 0.455273305926355 0.871350032640993 0.871350032640993 0.871350032640993
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Txndc5 ENSMUSG00000038991 0.89325623695993 0.89325623695993 0.420178502891541 0.89325623695993 0.632842448827872 0.89325623695993
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Fgl2 ENSMUSG00000039899 0.53004522287058 0.779281632899727 0.604991029214678 0.779281632899727 0.779281632899727 0.779281632899727
Tbc1d10c ENSMUSG00000040247 0.0489378623710267 0.14681358711308 0.648841705947697 0.865124455501488 0.865124455501488 0.865124455501488
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Arhgap9 ENSMUSG00000040345 0.25440003416661 0.692300745623403 0.609664489496356 0.692300745623403 0.692300745623403 0.692300745623403
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
Cd53 ENSMUSG00000040747 0.204230023552655 0.583085861213892 0.568786601077757 0.583085861213892 0.583085861213892 0.583085861213892
Lat2 ENSMUSG00000040751 0.266052463569623 0.79815739070887 0.877496843120831 0.877496843120831 0.837323356678055 0.877496843120831
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Serpinb1a ENSMUSG00000044734 0.955932521486043 0.955932521486043 0.90574767825056 0.955932521486043 0.629946409608427 0.955932521486043
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Fpr1 ENSMUSG00000045551 0.482505456036403 0.961596937566084 0.763297093452785 0.961596937566084 0.961596937566084 0.961596937566084
Plaur ENSMUSG00000046223 0.031290111184484 0.0938703335534521 0.727998969991539 0.727998969991539 0.724909794670447 0.727998969991539
Tifa ENSMUSG00000046688 0.797194835803375 0.965346849459665 0.965346849459665 0.965346849459665 0.812399545150088 0.965346849459665
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd300e ENSMUSG00000048498 0.362308350224987 0.804540447752196 0.857551973977173 0.857551973977173 0.536360298501464 0.804540447752196
C5ar1 ENSMUSG00000049130 2.12809609905041e-05 6.38428829715122e-05 0.430872871373441 0.646309307060162 0.675020900274284 0.675020900274284
Trappc1 ENSMUSG00000049299 0.0636197260554133 0.19085917816624 0.569499074646589 0.569499074646589 0.148148319811587 0.22222247971738
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Plekho2 ENSMUSG00000050721 0.125908406674103 0.377725220022309 0.661052734917824 0.661052734917824 0.530021902517946 0.661052734917824
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Pld4 ENSMUSG00000052160 0.00151338949273559 0.00227008423910338 0.00015532135136257 0.00046596405408771 0.00252467839912377 0.00252467839912377
Cd177 ENSMUSG00000052212 0.840260674462718 0.840260674462718 0.698397279822997 0.840260674462718 0.749576335810622 0.840260674462718
Fpr2 ENSMUSG00000052270 0.422001304935369 0.940160893469069 0.940160893469069 0.940160893469069 0.937022766115294 0.940160893469069
Hbb-bs ENSMUSG00000052305 0.177918733884123 0.184202917126453 0.0954928445167644 0.184202917126453 0.184202917126453 0.184202917126453
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Txk ENSMUSG00000054892 0.926341396843506 0.99679920942412 0.99679920942412 0.99679920942412 0.759118382235511 0.99679920942412
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Ptafr ENSMUSG00000056529 0.0441827335989428 0.132548200796828 0.593971401895849 0.602122704505769 0.602122704505769 0.602122704505769
Glipr1 ENSMUSG00000056888 0.184671633933133 0.554014901799398 0.880732772529595 0.880732772529595 0.632796650542833 0.880732772529595
Slc44a2 ENSMUSG00000057193 0.209630797175147 0.389429118761442 0.259619412507628 0.389429118761442 0.583072386391489 0.583072386391489
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Unc13d ENSMUSG00000057948 0.340681589288171 0.987403352398658 0.893257208399537 0.987403352398658 0.987403352398658 0.987403352398658
Nfam1 ENSMUSG00000058099 0.871059968930905 0.871059968930905 0.0371031239612186 0.111309371883656 0.141481193731918 0.212221790597878
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Pirb ENSMUSG00000058818 0.332702388332113 0.499053582498169 0.880725310592458 0.880725310592458 0.313012553202442 0.499053582498169
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Atp8b4 ENSMUSG00000060131 0.914606757652261 0.914606757652261 0.742671503030267 0.914606757652261 0.326925863650837 0.914606757652261
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Gmfg ENSMUSG00000060791 0.630004717252735 0.749184080834323 0.749184080834323 0.749184080834323 0.445726456417397 0.749184080834323
Prcp ENSMUSG00000061119 0.352837135755494 0.671859704909435 0.806643889978581 0.806643889978581 0.447906469939623 0.671859704909435
Efcab4b ENSMUSG00000061414 0.736077129430565 0.962120919858673 0.962120919858673 0.962120919858673 0.58373308079493 0.962120919858673
Cd300lb ENSMUSG00000063193 0.0207312822843939 0.0621938468531818 0.570511330654218 0.661128772713596 0.661128772713596 0.661128772713596
Rab44 ENSMUSG00000064147 0.240858243998035 0.240858243998035 0.139752249953515 0.215365210573624 0.143576807049083 0.215365210573624
Ano6 ENSMUSG00000064210 0.646693915422459 0.880681105629327 0.658293185525752 0.880681105629327 0.880681105629327 0.880681105629327
Hvcn1 ENSMUSG00000064267 0.521948935143001 0.77308424723638 0.77308424723638 0.77308424723638 0.596377119652557 0.77308424723638
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Cpped1 ENSMUSG00000065979 0.955927933831199 0.955927933831199 0.18468407060505 0.55405221181515 0.54827981290724 0.822419719360861
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Lyz2 ENSMUSG00000069516 0.42459148370476 0.564042324168096 0.320942239145082 0.564042324168096 0.564042324168096 0.564042324168096
Nlrp1a ENSMUSG00000069830 0.522940617415826 0.784410926123738 0.893200773561383 0.893200773561383 0.35492385366701 0.784410926123738
Lilra5 ENSMUSG00000070873 0.855929610640207 0.855929610640207 0.471740515136299 0.855929610640207 0.840368362498668 0.855929610640207
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Ear2 ENSMUSG00000072596 0.216760398415574 0.50672335410396 0.50672335410396 0.50672335410396 0.489114359644712 0.50672335410396
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
Hbb-bt ENSMUSG00000073940 0.0899400920737443 0.109415412755815 0.0351389280678127 0.105416784203438 0.109415412755815 0.109415412755815
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
C5ar2 ENSMUSG00000074361 0.4263099087702 0.6394648631553 0.379598781320832 0.6394648631553 0.770156442663169 0.770156442663169
Gm14548 ENSMUSG00000074417 0.407777464874274 0.534334354372858 0.534334354372858 0.534334354372858 0.473292008332101 0.534334354372858
Sirpb1c ENSMUSG00000074677 0.579356914885657 0.869035372328486 0.283768706558931 0.851306119676793 0.984157520402225 0.984157520402225
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115
Ighg2c ENSMUSG00000076612 0.548099743416651 0.724696349762504 0.724696349762504 0.724696349762504 0.598008175272639 0.724696349762504
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379
Pira2 ENSMUSG00000089942 0.490037291108727 0.735055936663091 0.870817218757294 0.870817218757294 0.390389473033881 0.735055936663091
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Gm20547 ENSMUSG00000092511 0.764375811023646 0.993443816439094 0.0586286027899168 0.175885808369751 0.993443816439094 0.993443816439094
Sirpb1b ENSMUSG00000095028 0.884834703790803 0.910771720569585 0.910771720569585 0.910771720569585 0.402516263798805 0.910771720569585
Dynlt1f ENSMUSG00000095677 0.257945480483416 0.773836441450247 0.98425720956738 0.98425720956738 0.661229284453844 0.98425720956738
Sirpb1a ENSMUSG00000095788 0.206684240616655 0.409326851364192 0.510394876146869 0.510394876146869 0.272884567576128 0.409326851364192
Dynlt1b ENSMUSG00000096255 0.292852511124036 0.810691676773085 0.965374357523301 0.965374357523301 0.540461117848723 0.810691676773085

Resolution of Sister Chromatid Cohesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Cdca5 ENSMUSG00000024791 0.910297979142037 0.944832307332191 0.356014935371692 0.944832307332191 0.944832307332191 0.944832307332191
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Ppp4c ENSMUSG00000030697 0.0592125528199272 0.0888188292298908 0.0405678931068457 0.0888188292298908 0.543076952932224 0.543076952932224
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Tipin ENSMUSG00000032397 0.167415262600935 0.502245787802805 0.596543418981314 0.894815128471971 0.946411756114403 0.946411756114403
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Timeless ENSMUSG00000039994 0.862002146024331 0.862002146024331 0.44108597923605 0.711344769384679 0.474229846256453 0.711344769384679
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Generation of second messenger molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Fyb ENSMUSG00000022148 0.0121348140217551 0.0364044420652652 0.68404209569131 0.68404209569131 0.46432641922888 0.68404209569131
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666
Cd101 ENSMUSG00000086564 0.977724476809487 0.977724476809487 0.610102369589349 0.915153554384024 0.395129040096097 0.915153554384024

DNA strand elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

DNA Double-Strand Break Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Kpna2 ENSMUSG00000018362 0.175528060391153 0.526584181173458 0.695929704838194 0.740151595502956 0.740151595502956 0.740151595502956
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Polm ENSMUSG00000020474 0.397731276536172 0.585803028615596 0.585803028615596 0.585803028615596 0.373813271180803 0.585803028615596
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Ppp4c ENSMUSG00000030697 0.0592125528199272 0.0888188292298908 0.0405678931068457 0.0888188292298908 0.543076952932224 0.543076952932224
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Tipin ENSMUSG00000032397 0.167415262600935 0.502245787802805 0.596543418981314 0.894815128471971 0.946411756114403 0.946411756114403
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Kdm4a ENSMUSG00000033326 0.516431024133573 0.618390058445737 0.509533967725205 0.618390058445737 0.618390058445737 0.618390058445737
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Polq ENSMUSG00000034206 0.757834625288544 0.971659899649896 0.971659899649896 0.971659899649896 0.843274394860513 0.971659899649896
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Timeless ENSMUSG00000039994 0.862002146024331 0.862002146024331 0.44108597923605 0.711344769384679 0.474229846256453 0.711344769384679
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mitotic Spindle Checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

Homologous DNA Pairing and Strand Exchange

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228

DNA Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Fancl ENSMUSG00000004018 0.560801715774823 0.841202573662235 0.548089856730846 0.841202573662235 0.965299516532591 0.965299516532591
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Kpna2 ENSMUSG00000018362 0.175528060391153 0.526584181173458 0.695929704838194 0.740151595502956 0.740151595502956 0.740151595502956
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Polm ENSMUSG00000020474 0.397731276536172 0.585803028615596 0.585803028615596 0.585803028615596 0.373813271180803 0.585803028615596
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Yy1 ENSMUSG00000021264 0.393289234821783 0.883898254985362 0.883898254985362 0.883898254985362 0.764188125850636 0.883898254985362
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Ube2t ENSMUSG00000026429 0.812371394411998 0.84343594358458 0.84343594358458 0.84343594358458 0.840234771316459 0.84343594358458
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Dclre1b ENSMUSG00000027845 0.0940441007317195 0.282132302195158 0.883895513132892 0.883895513132892 0.46476869742419 0.697153046136285
Chd1l ENSMUSG00000028089 0.698783983895017 0.698783983895017 0.233694116682994 0.698783983895017 0.646931914948733 0.698783983895017
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Usp1 ENSMUSG00000028560 0.434058003510885 0.94336484193188 0.687164372043649 0.94336484193188 0.94336484193188 0.94336484193188
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Mutyh ENSMUSG00000028687 0.574867504158502 0.77019634576434 0.77019634576434 0.77019634576434 0.664040896456067 0.77019634576434
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Ogg1 ENSMUSG00000030271 0.0442716123757612 0.132814837127284 0.438688139246743 0.658032208870115 0.734226035946159 0.734226035946159
C230052I12Rik ENSMUSG00000030493 0.426929509260589 0.542971452620046 0.235190764095948 0.542971452620046 0.542971452620046 0.542971452620046
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Ppp4c ENSMUSG00000030697 0.0592125528199272 0.0888188292298908 0.0405678931068457 0.0888188292298908 0.543076952932224 0.543076952932224
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Neil1 ENSMUSG00000032298 0.552851047579205 0.829276571368808 0.388947726176355 0.829276571368808 0.830863465675073 0.830863465675073
Tipin ENSMUSG00000032397 0.167415262600935 0.502245787802805 0.596543418981314 0.894815128471971 0.946411756114403 0.946411756114403
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Fanca ENSMUSG00000032815 0.893226156598959 0.940210255277229 0.69580320712939 0.940210255277229 0.940210255277229 0.940210255277229
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Kdm4a ENSMUSG00000033326 0.516431024133573 0.618390058445737 0.509533967725205 0.618390058445737 0.618390058445737 0.618390058445737
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Polq ENSMUSG00000034206 0.757834625288544 0.971659899649896 0.971659899649896 0.971659899649896 0.843274394860513 0.971659899649896
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Dtl ENSMUSG00000037474 0.923090510524295 0.923090510524295 0.823872593858888 0.923090510524295 0.834219505568798 0.923090510524295
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Fanci ENSMUSG00000039187 0.575451316965023 0.930750441583897 0.930750441583897 0.930750441583897 0.849985040178575 0.930750441583897
Neil3 ENSMUSG00000039396 0.993650763435805 0.993650763435805 0.943342252092692 0.993650763435805 0.908172903048363 0.993650763435805
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Timeless ENSMUSG00000039994 0.862002146024331 0.862002146024331 0.44108597923605 0.711344769384679 0.474229846256453 0.711344769384679
2810417H13Rik ENSMUSG00000040204 0.0224448522469945 0.0673345567409836 0.290970842858207 0.43645626428731 0.641283872893846 0.641283872893846
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Zfp830 ENSMUSG00000046010 0.574968999682525 0.831211863248003 0.481959295162291 0.831211863248003 0.831211863248003 0.831211863248003
Ino80c ENSMUSG00000047989 0.761172578700378 0.877669131162382 0.877669131162382 0.877669131162382 0.404419970120681 0.877669131162382
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Presynaptic phase of homologous DNA pairing and strand exchange

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228

Signaling by Rho GTPases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Stard13 ENSMUSG00000016128 0.30387918614813 0.582988097134103 0.509414294016634 0.582988097134103 0.582988097134103 0.582988097134103
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Diap3 ENSMUSG00000022021 0.885266457018139 0.885266457018139 0.377609236104622 0.885266457018139 0.825421081649594 0.885266457018139
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Fmnl3 ENSMUSG00000023008 0.158539230267744 0.39771690707546 0.36330781619577 0.39771690707546 0.39771690707546 0.39771690707546
Racgap1 ENSMUSG00000023015 0.794313006390566 0.794313006390566 0.357059373567292 0.794313006390566 0.758021625116786 0.794313006390566
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Fgd2 ENSMUSG00000024013 0.161857626162729 0.242786439244094 0.322838555032344 0.322838555032344 0.107991630713536 0.242786439244094
Arhgap28 ENSMUSG00000024043 0.574951433394489 0.74610784063236 0.367411649641464 0.74610784063236 0.74610784063236 0.74610784063236
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Arhgap19 ENSMUSG00000025154 0.601745027530283 0.896360176505161 0.896360176505161 0.896360176505161 0.75783155093698 0.896360176505161
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Pkn3 ENSMUSG00000026785 0.731289689848808 0.731289689848808 0.388975707406934 0.583463561110401 0.271563078222944 0.583463561110401
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Ect2 ENSMUSG00000027699 0.77792794697507 0.890086585145094 0.890086585145094 0.890086585145094 0.833265230652966 0.890086585145094
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Iqgap3 ENSMUSG00000028068 0.243392649306631 0.365088973959946 0.113567006554015 0.340701019662046 0.458382691522496 0.458382691522496
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Arhgef19 ENSMUSG00000028919 0.607756072023105 0.911634108034657 0.0807069523274936 0.242120856982481 0.987400096134984 0.987400096134984
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rhoh ENSMUSG00000029204 0.559248188445637 0.838499133667078 0.838499133667078 0.838499133667078 0.793261255914589 0.838499133667078
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Arhgap25 ENSMUSG00000030047 0.846533925730108 0.846533925730108 0.136009832925791 0.408029498777372 0.626930637445819 0.846533925730108
Arhgdib ENSMUSG00000030220 0.788017735679079 0.788017735679079 0.521724042479907 0.782586063719861 0.369434725138607 0.782586063719861
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Arhgap17 ENSMUSG00000030766 0.79138773047178 0.981103593725019 0.981103593725019 0.981103593725019 0.933942610623993 0.981103593725019
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Flna ENSMUSG00000031328 0.812768584424391 0.812768584424391 0.615990120361259 0.812768584424391 0.564120147031627 0.812768584424391
Arhgap4 ENSMUSG00000031389 0.179152683358928 0.322614527171677 0.322614527171677 0.322614527171677 0.29597392091135 0.322614527171677
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Arap1 ENSMUSG00000032812 0.506909857600896 0.506909857600896 0.116482487917738 0.295236908481071 0.196824605654048 0.295236908481071
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Tagap ENSMUSG00000033450 0.112215639600214 0.336646918800641 0.461393729290757 0.692090593936136 0.834040055622936 0.834040055622936
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Arhgap27 ENSMUSG00000034255 0.946508345874803 0.987404943025016 0.987404943025016 0.987404943025016 0.537849620675317 0.987404943025016
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Hmha1 ENSMUSG00000035697 0.172244269892772 0.172244269892772 0.0142213787902949 0.0426641363708846 0.0594695573239394 0.0892043359859091
Gmip ENSMUSG00000036246 0.758132072808888 0.86520822896554 0.596739623671852 0.86520822896554 0.86520822896554 0.86520822896554
Prc1 ENSMUSG00000038943 0.373757452673877 0.628142132046485 0.418761421364323 0.628142132046485 0.712427555029132 0.712427555029132
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Arhgap9 ENSMUSG00000040345 0.25440003416661 0.692300745623403 0.609664489496356 0.692300745623403 0.692300745623403 0.692300745623403
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Arhgef10l ENSMUSG00000040964 0.196764129563487 0.350384610621833 0.233589740414555 0.350384610621833 0.585826905562777 0.585826905562777
Arhgap11a ENSMUSG00000041219 0.640384662040894 0.867987120997331 0.69006302409137 0.867987120997331 0.867987120997331 0.867987120997331
Kif14 ENSMUSG00000041498 0.927406634335313 0.927406634335313 0.795430810323814 0.927406634335313 0.8900799978083 0.927406634335313
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Arhgap15 ENSMUSG00000049744 0.646519630440445 0.646519630440445 0.641200397277372 0.646519630440445 0.452253361056191 0.646519630440445
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Akap13 ENSMUSG00000066406 0.669623676240994 0.987398272706954 0.89324541901726 0.987398272706954 0.987398272706954 0.987398272706954
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115

Signaling by Rho GTPases, Miro GTPases and RHOBTB3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pkn2 ENSMUSG00000004591 0.124065133648447 0.372195400945342 0.779271810789035 0.779271810789035 0.761115088791748 0.779271810789035
Arpc2 ENSMUSG00000006304 0.46732863287622 0.815869641090122 0.815869641090122 0.815869641090122 0.731278697046358 0.815869641090122
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
Stard13 ENSMUSG00000016128 0.30387918614813 0.582988097134103 0.509414294016634 0.582988097134103 0.582988097134103 0.582988097134103
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Diap3 ENSMUSG00000022021 0.885266457018139 0.885266457018139 0.377609236104622 0.885266457018139 0.825421081649594 0.885266457018139
Myh9 ENSMUSG00000022443 0.669763063605651 0.669763063605651 0.276677854352093 0.669763063605651 0.537752406887323 0.669763063605651
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Fmnl3 ENSMUSG00000023008 0.158539230267744 0.39771690707546 0.36330781619577 0.39771690707546 0.39771690707546 0.39771690707546
Racgap1 ENSMUSG00000023015 0.794313006390566 0.794313006390566 0.357059373567292 0.794313006390566 0.758021625116786 0.794313006390566
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Fgd2 ENSMUSG00000024013 0.161857626162729 0.242786439244094 0.322838555032344 0.322838555032344 0.107991630713536 0.242786439244094
Arhgap28 ENSMUSG00000024043 0.574951433394489 0.74610784063236 0.367411649641464 0.74610784063236 0.74610784063236 0.74610784063236
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Arhgap19 ENSMUSG00000025154 0.601745027530283 0.896360176505161 0.896360176505161 0.896360176505161 0.75783155093698 0.896360176505161
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Actr3 ENSMUSG00000026341 0.896380578437952 0.896380578437952 0.664102242240384 0.896380578437952 0.822001166563347 0.896380578437952
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Pkn3 ENSMUSG00000026785 0.731289689848808 0.731289689848808 0.388975707406934 0.583463561110401 0.271563078222944 0.583463561110401
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Ect2 ENSMUSG00000027699 0.77792794697507 0.890086585145094 0.890086585145094 0.890086585145094 0.833265230652966 0.890086585145094
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Iqgap3 ENSMUSG00000028068 0.243392649306631 0.365088973959946 0.113567006554015 0.340701019662046 0.458382691522496 0.458382691522496
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Wasf2 ENSMUSG00000028868 0.313319547447711 0.939958642343132 0.940213195104911 0.940213195104911 0.788366616077505 0.940213195104911
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Arhgef19 ENSMUSG00000028919 0.607756072023105 0.911634108034657 0.0807069523274936 0.242120856982481 0.987400096134984 0.987400096134984
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rhoh ENSMUSG00000029204 0.559248188445637 0.838499133667078 0.838499133667078 0.838499133667078 0.793261255914589 0.838499133667078
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Arpc3 ENSMUSG00000029465 0.630049347635539 0.630049347635539 0.616068208894937 0.630049347635539 0.550967078990247 0.630049347635539
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Arpc1b ENSMUSG00000029622 0.344763424361242 0.344763424361242 0.206765885458176 0.344763424361242 0.236617948318011 0.344763424361242
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Arhgap25 ENSMUSG00000030047 0.846533925730108 0.846533925730108 0.136009832925791 0.408029498777372 0.626930637445819 0.846533925730108
Arhgdib ENSMUSG00000030220 0.788017735679079 0.788017735679079 0.521724042479907 0.782586063719861 0.369434725138607 0.782586063719861
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Arhgap17 ENSMUSG00000030766 0.79138773047178 0.981103593725019 0.981103593725019 0.981103593725019 0.933942610623993 0.981103593725019
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Flna ENSMUSG00000031328 0.812768584424391 0.812768584424391 0.615990120361259 0.812768584424391 0.564120147031627 0.812768584424391
Arhgap4 ENSMUSG00000031389 0.179152683358928 0.322614527171677 0.322614527171677 0.322614527171677 0.29597392091135 0.322614527171677
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Arap1 ENSMUSG00000032812 0.506909857600896 0.506909857600896 0.116482487917738 0.295236908481071 0.196824605654048 0.295236908481071
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Tagap ENSMUSG00000033450 0.112215639600214 0.336646918800641 0.461393729290757 0.692090593936136 0.834040055622936 0.834040055622936
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Arhgap27 ENSMUSG00000034255 0.946508345874803 0.987404943025016 0.987404943025016 0.987404943025016 0.537849620675317 0.987404943025016
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Hmha1 ENSMUSG00000035697 0.172244269892772 0.172244269892772 0.0142213787902949 0.0426641363708846 0.0594695573239394 0.0892043359859091
Gmip ENSMUSG00000036246 0.758132072808888 0.86520822896554 0.596739623671852 0.86520822896554 0.86520822896554 0.86520822896554
Prc1 ENSMUSG00000038943 0.373757452673877 0.628142132046485 0.418761421364323 0.628142132046485 0.712427555029132 0.712427555029132
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Arhgap9 ENSMUSG00000040345 0.25440003416661 0.692300745623403 0.609664489496356 0.692300745623403 0.692300745623403 0.692300745623403
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Arhgef10l ENSMUSG00000040964 0.196764129563487 0.350384610621833 0.233589740414555 0.350384610621833 0.585826905562777 0.585826905562777
Arhgap11a ENSMUSG00000041219 0.640384662040894 0.867987120997331 0.69006302409137 0.867987120997331 0.867987120997331 0.867987120997331
Kif14 ENSMUSG00000041498 0.927406634335313 0.927406634335313 0.795430810323814 0.927406634335313 0.8900799978083 0.927406634335313
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Arhgap15 ENSMUSG00000049744 0.646519630440445 0.646519630440445 0.641200397277372 0.646519630440445 0.452253361056191 0.646519630440445
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Pkn1 ENSMUSG00000057672 0.746186707519797 0.843567261463853 0.569619183029421 0.843567261463853 0.843567261463853 0.843567261463853
Akap13 ENSMUSG00000066406 0.669623676240994 0.987398272706954 0.89324541901726 0.987398272706954 0.987398272706954 0.987398272706954
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774
Wipf1 ENSMUSG00000075284 0.365291571109283 0.707584639418115 0.707584639418115 0.707584639418115 0.629908096775408 0.707584639418115

DNA Replication Pre-Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Chromosome Maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Mis18a ENSMUSG00000022978 0.981109162888008 0.981109162888008 0.877663099932883 0.981109162888008 0.561547563685078 0.981109162888008
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ppp6r3 ENSMUSG00000024908 0.725285226401555 0.776262387276821 0.43158823472778 0.776262387276821 0.776262387276821 0.776262387276821
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Nop10 ENSMUSG00000027133 0.433963194739969 0.585808307031612 0.585808307031612 0.585808307031612 0.251190405158169 0.585808307031612
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Shq1 ENSMUSG00000035378 0.693023808714369 0.693023808714369 0.156197266551862 0.355252234363206 0.236834822908804 0.355252234363206
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Pif1 ENSMUSG00000041064 0.778619210639809 0.942399990559268 0.942399990559268 0.942399990559268 0.808405022155022 0.942399990559268
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Mis18bp1 ENSMUSG00000047534 0.451294432983342 0.676941649475013 0.870765548937771 0.870765548937771 0.442816310918232 0.676941649475013
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Oip5 ENSMUSG00000072980 0.879701243029315 0.930060290012718 0.428937086467369 0.930060290012718 0.930060290012718 0.930060290012718
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Cenpw ENSMUSG00000075266 0.582559292756862 0.582559292756862 0.361196903438474 0.582559292756862 0.558383067549043 0.582559292756862

EML4 and NUDC in mitotic spindle formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

Mitotic G1 phase and G1/S transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Activation of ATR in response to replication stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456

Polymerase switching

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Leading Strand Synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

RHO GTPases Activate Formins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Pfn1 ENSMUSG00000018293 0.698633512137435 0.800568614867594 0.0412533537532485 0.123760061259746 0.800568614867594 0.800568614867594
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Diap3 ENSMUSG00000022021 0.885266457018139 0.885266457018139 0.377609236104622 0.885266457018139 0.825421081649594 0.885266457018139
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Fmnl3 ENSMUSG00000023008 0.158539230267744 0.39771690707546 0.36330781619577 0.39771690707546 0.39771690707546 0.39771690707546
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Sgol1 ENSMUSG00000023940 0.175130656296265 0.525391968888796 0.677805475377101 0.677805475377101 0.576265528637243 0.677805475377101
Ndc80 ENSMUSG00000024056 0.449694003992393 0.873497495040467 0.840036279267252 0.873497495040467 0.873497495040467 0.873497495040467
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Sgol2 ENSMUSG00000026039 0.831101390220559 0.831101390220559 0.794407538342061 0.831101390220559 0.71629320679118 0.831101390220559
Cenpf ENSMUSG00000026605 0.571073404486271 0.904372432728983 0.632774789887359 0.904372432728983 0.904372432728983 0.904372432728983
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Nuf2 ENSMUSG00000026683 0.806486149276728 0.806486149276728 0.462438613354026 0.806486149276728 0.618552761284978 0.806486149276728
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
Pmf1 ENSMUSG00000028066 0.285476405571782 0.428214608357673 0.0734135447405724 0.220240634221717 0.464723813328321 0.464723813328321
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Kntc1 ENSMUSG00000029414 0.404780685111638 0.76211986552042 0.619854524183906 0.76211986552042 0.76211986552042 0.76211986552042
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
Zw10 ENSMUSG00000032264 0.902615973799442 0.902615973799442 0.429410309464056 0.644115464196084 0.406615631771409 0.644115464196084
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Gm9846 ENSMUSG00000050621 0.029149328285113 0.0874479848553389 0.644144287195322 0.644144287195322 0.395552312991702 0.593328469487553
Ercc6l ENSMUSG00000051220 0.908396386913386 0.908396386913386 0.47610622691587 0.908396386913386 0.715218067704026 0.908396386913386
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Spdl1 ENSMUSG00000069910 0.599170029948619 0.965322120666793 0.965322120666793 0.965322120666793 0.965300912361788 0.965322120666793
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Spc24 ENSMUSG00000074476 0.496679967206769 0.499343634817774 0.499343634817774 0.499343634817774 0.491577976973336 0.499343634817774

G1/S Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of TP53 Activity through Phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TNFR2 non-canonical NF-kB pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Tnfsf8 ENSMUSG00000028362 0.572378473457636 0.585516979927963 0.535638996314391 0.585516979927963 0.585516979927963 0.585516979927963
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Tnfrsf9 ENSMUSG00000028965 0.551979116404505 0.849045304877206 0.778404727857629 0.849045304877206 0.849045304877206 0.849045304877206
Cd27 ENSMUSG00000030336 0.63681419423859 0.855166267900634 0.855166267900634 0.855166267900634 0.426478775983714 0.855166267900634
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Tnfsf9 ENSMUSG00000035678 0.868119017145407 0.930773105897805 0.930773105897805 0.930773105897805 0.352566427942107 0.930773105897805
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Tnfrsf18 ENSMUSG00000041954 0.565886325135964 0.848829487703946 0.398530238309786 0.848829487703946 0.93922116070972 0.93922116070972
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Tnfsf12 ENSMUSG00000097328 0.561531635206684 0.842297452810027 0.322979008125066 0.842297452810027 0.943358622315216 0.943358622315216

Signaling by Interleukins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Il12rb1 ENSMUSG00000000791 0.855842698092083 0.855842698092083 0.550374117862499 0.855842698092083 0.629705925526571 0.855842698092083
Il16 ENSMUSG00000001741 0.611930619841571 0.611930619841571 0.395741565598107 0.593612348397161 0.0545775042155176 0.163732512646553
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Ebi3 ENSMUSG00000003206 0.965320343149152 0.965320343149152 0.243627680256872 0.730883040770617 0.794410637753496 0.965320343149152
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Il7r ENSMUSG00000003882 0.162708239916523 0.48812471974957 0.72855905861864 0.919837201281667 0.919837201281667 0.919837201281667
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tslp ENSMUSG00000024379 0.132548241130065 0.397644723390196 0.449777273641288 0.449777273641288 0.352429033437292 0.449777273641288
Csf1r ENSMUSG00000024621 0.776200291495287 0.776200291495287 0.0239326513724279 0.0717979541172838 0.096539432138376 0.144809148207564
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1rl1 ENSMUSG00000026069 0.261767210688227 0.751371986150376 0.751371986150376 0.751371986150376 0.594440646111953 0.751371986150376
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Il6ra ENSMUSG00000027947 0.196480320041292 0.362186134773443 0.649549635795342 0.649549635795342 0.241457423182295 0.362186134773443
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Csf3r ENSMUSG00000028859 0.924498509090659 0.924498509090659 0.417917443853171 0.626876165779756 0.140356522661848 0.421069567985545
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Il4ra ENSMUSG00000030748 0.54812393566677 0.54812393566677 0.330518725377377 0.54812393566677 0.392958403600378 0.54812393566677
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Clcf1 ENSMUSG00000040663 0.172236824241387 0.25835523636208 0.987404528198245 0.987404528198245 0.0903124155374292 0.25835523636208
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Il31ra ENSMUSG00000050377 0.849572606020411 0.888445216680373 0.888445216680373 0.888445216680373 0.808998783693655 0.888445216680373
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Osm ENSMUSG00000058755 0.547484701453807 0.91462465109069 0.65860968815863 0.91462465109069 0.91462465109069 0.91462465109069
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Il1rl2 ENSMUSG00000070942 0.736254623457522 0.736254623457522 0.715767190861718 0.736254623457522 0.66882612900309 0.736254623457522
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Termination of translesion DNA synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
2810417H13Rik ENSMUSG00000040204 0.0224448522469945 0.0673345567409836 0.290970842858207 0.43645626428731 0.641283872893846 0.641283872893846
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Activation of the pre-replicative complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc45 ENSMUSG00000000028 0.626411595121098 0.933910137200441 0.933910137200441 0.933910137200441 0.933268173818781 0.933910137200441
Dbf4 ENSMUSG00000002297 0.524289385327039 0.593764847599155 0.593764847599155 0.593764847599155 0.354561331294153 0.593764847599155
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603

HDR through Single Strand Annealing (SSA)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559

Lagging Strand Synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Extension of Telomeres

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ppp6r3 ENSMUSG00000024908 0.725285226401555 0.776262387276821 0.43158823472778 0.776262387276821 0.776262387276821 0.776262387276821
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Nop10 ENSMUSG00000027133 0.433963194739969 0.585808307031612 0.585808307031612 0.585808307031612 0.251190405158169 0.585808307031612
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Shq1 ENSMUSG00000035378 0.693023808714369 0.693023808714369 0.156197266551862 0.355252234363206 0.236834822908804 0.355252234363206
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Pif1 ENSMUSG00000041064 0.778619210639809 0.942399990559268 0.942399990559268 0.942399990559268 0.808405022155022 0.942399990559268

Interleukin-1 family signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1rl1 ENSMUSG00000026069 0.261767210688227 0.751371986150376 0.751371986150376 0.751371986150376 0.594440646111953 0.751371986150376
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Il1rl2 ENSMUSG00000070942 0.736254623457522 0.736254623457522 0.715767190861718 0.736254623457522 0.66882612900309 0.736254623457522
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Resolution of D-loop Structures through Holliday Junction Intermediates

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228

Resolution of D-Loop Structures

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rad51d ENSMUSG00000018841 0.21401535386586 0.32102303079879 0.179528218000678 0.32102303079879 0.464893694464007 0.464893694464007
Rad51 ENSMUSG00000027323 0.71307690316214 0.71307690316214 0.39111560191413 0.71307690316214 0.519153111702622 0.71307690316214
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Brca2 ENSMUSG00000041147 0.514428137244372 1 0.686898055651384 1 1 1
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Spidr ENSMUSG00000041974 0.593975072783233 0.815866349757173 0.773208989038654 0.815866349757173 0.815866349757173 0.815866349757173
Palb2 ENSMUSG00000044702 0.987398365657567 0.987398365657567 0.803533142698367 0.987398365657567 0.911920446009809 0.987398365657567
Gen1 ENSMUSG00000051235 0.485890103301415 0.649228850011059 0.456654517186597 0.649228850011059 0.649228850011059 0.649228850011059
Rad51b ENSMUSG00000059060 0.636805686319676 0.891232325214228 0.472030092367117 0.891232325214228 0.891232325214228 0.891232325214228

Downstream TCR signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Telomere C-strand (Lagging Strand) Synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Regulation of mitotic cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

APC/C-mediated degradation of cell cycle proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Interleukin-1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Il1r2 ENSMUSG00000026073 0.928680930409944 0.928680930409944 0.832445334412473 0.928680930409944 0.922667725622714 0.928680930409944
Il1rn ENSMUSG00000026981 0.664276760683024 0.967981210272167 0.967981210272167 0.967981210272167 0.589346144370525 0.967981210272167
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Irak4 ENSMUSG00000059883 0.707606740218126 0.785344661386311 0.486859592597268 0.785344661386311 0.785344661386311 0.785344661386311
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
2810417H13Rik ENSMUSG00000040204 0.0224448522469945 0.0673345567409836 0.290970842858207 0.43645626428731 0.641283872893846 0.641283872893846
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Gap-filling DNA repair synthesis and ligation in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

C-type lectin receptors (CLRs)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Clec4n ENSMUSG00000023349 0.66366094094944 0.911880328065958 0.911880328065958 0.911880328065958 0.788291202279061 0.911880328065958
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Phosphorylation of CD3 and TCR zeta chains

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Ptpn22 ENSMUSG00000027843 0.911431699891067 0.949348855133307 0.655124708730282 0.949348855133307 0.949348855133307 0.949348855133307
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666

Translocation of ZAP-70 to Immunological synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Ptpn22 ENSMUSG00000027843 0.911431699891067 0.949348855133307 0.655124708730282 0.949348855133307 0.949348855133307 0.949348855133307
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666

Adaptive Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Icosl ENSMUSG00000000732 0.943338320115267 0.943338320115267 0.501935949796012 0.752903924694018 0.230396936429296 0.691190809287889
Icam4 ENSMUSG00000001014 0.23905517617492 0.717165528524759 0.949568439846291 0.949568439846291 0.641141721440614 0.949568439846291
Icam2 ENSMUSG00000001029 0.319001661185206 0.319001661185206 0.179225746614391 0.319001661185206 0.301910955686919 0.319001661185206
Itgb7 ENSMUSG00000001281 0.48132130495389 0.567627766974722 0.567627766974722 0.567627766974722 0.484733138035319 0.567627766974722
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Cd79a ENSMUSG00000003379 0.0234760756176181 0.0704282268528543 0.290616414871814 0.435924622307721 0.864931461359157 0.864931461359157
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Ctse ENSMUSG00000004552 0.918856052119456 0.918856052119456 0.251187453998696 0.753562361996087 0.875521104001122 0.918856052119456
Cd33 ENSMUSG00000004609 0.624162076310881 0.896366932455738 0.896366932455738 0.896366932455738 0.103692509204485 0.311077527613454
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rnf114 ENSMUSG00000006418 0.0707966072931103 0.120039356593871 0.0800262377292472 0.120039356593871 0.252757817940992 0.252757817940992
Kif11 ENSMUSG00000012443 0.450940791551811 0.833564413145664 0.632333222901336 0.833564413145664 0.833564413145664 0.833564413145664
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Slamf6 ENSMUSG00000015314 0.292349484278281 0.652848914047876 0.641048050919389 0.652848914047876 0.652848914047876 0.652848914047876
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Ctsa ENSMUSG00000017760 0.725083813702546 0.725083813702546 0.136195903706912 0.204293855560368 0.0596331974328757 0.178899592298627
Rnf130 ENSMUSG00000020376 0.779244330734161 0.779244330734161 0.103052317322185 0.309156951966555 0.722347995785867 0.779244330734161
Itk ENSMUSG00000020395 0.329580755821501 0.565153176843318 0.565153176843318 0.565153176843318 0.560874793628951 0.565153176843318
Trim11 ENSMUSG00000020455 0.481903950518292 0.921385412007054 0.921385412007054 0.921385412007054 0.865239626150503 0.921385412007054
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Fyb ENSMUSG00000022148 0.0121348140217551 0.0364044420652652 0.68404209569131 0.68404209569131 0.46432641922888 0.68404209569131
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Rnf19a ENSMUSG00000022280 0.553540091056412 0.644077203144885 0.644077203144885 0.644077203144885 0.574913942850289 0.644077203144885
Cd96 ENSMUSG00000022657 0.262283600503039 0.496819237597611 0.331212825065074 0.496819237597611 0.632241161299147 0.632241161299147
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Racgap1 ENSMUSG00000023015 0.794313006390566 0.794313006390566 0.357059373567292 0.794313006390566 0.758021625116786 0.794313006390566
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Ube2j2 ENSMUSG00000023286 0.44779564108259 0.516937784476093 0.175699016113411 0.516937784476093 0.516937784476093 0.516937784476093
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Kifc5b ENSMUSG00000024301 0.362067247816443 0.981108933046529 0.981108933046529 0.981108933046529 0.849306098448655 0.981108933046529
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
H2-Oa ENSMUSG00000024334 0.00238365369940052 0.00715096109820156 0.327056839893695 0.327056839893695 0.263845132842629 0.327056839893695
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Cd74 ENSMUSG00000024610 0.491779704689238 0.643983510924004 0.2731036564511 0.643983510924004 0.643983510924004 0.643983510924004
Kif20b ENSMUSG00000024795 0.181620741863458 0.429863611386073 0.524623416289839 0.524623416289839 0.286575740924049 0.429863611386073
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Pik3ap1 ENSMUSG00000025017 0.99369399236377 0.99369399236377 0.899461146927869 0.99369399236377 0.754761678074681 0.99369399236377
Ifitm1 ENSMUSG00000025491 0.846628774219761 0.955920688024455 0.955920688024455 0.955920688024455 0.402092636721738 0.955920688024455
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Zap70 ENSMUSG00000026117 0.687109036525459 0.84662765758581 0.84662765758581 0.84662765758581 0.629976599872377 0.84662765758581
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Kif18a ENSMUSG00000027115 0.632763487276954 0.775726238159873 0.409461475127977 0.775726238159873 0.775726238159873 0.775726238159873
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ptpn22 ENSMUSG00000027843 0.911431699891067 0.949348855133307 0.655124708730282 0.949348855133307 0.949348855133307 0.949348855133307
Vcam1 ENSMUSG00000027962 0.996850261384786 0.996850261384786 0.849704623087423 0.996850261384786 0.307638840045107 0.922916520135322
Them4 ENSMUSG00000028145 0.153778717005039 0.461336151015118 0.610465737405268 0.915698606107901 0.940224030723688 0.940224030723688
Dapp1 ENSMUSG00000028159 0.921332971189463 0.921332971189463 0.695945259915935 0.921332971189463 0.352619245541218 0.921332971189463
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Kif2c ENSMUSG00000028678 0.503365281573902 0.657586299708452 0.657586299708452 0.657586299708452 0.176954271402345 0.530862814207035
Rnf19b ENSMUSG00000028793 0.532645053624408 0.798967580436612 0.296517106759042 0.798967580436612 0.818939226902113 0.818939226902113
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Herc6 ENSMUSG00000029798 0.612950298138434 0.713439177396024 0.346357654321052 0.713439177396024 0.713439177396024 0.713439177396024
Lag3 ENSMUSG00000030124 0.0293339755433157 0.0880019266299471 0.468392170911408 0.468392170911408 0.442396426854509 0.468392170911408
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Siglecg ENSMUSG00000030468 0.247620943271295 0.742862829813885 0.95802095183943 0.95802095183943 0.941902228360924 0.95802095183943
Siglece ENSMUSG00000030474 0.292191785373393 0.438287678060089 0.285214487265963 0.438287678060089 0.601980510117661 0.601980510117661
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Kif22 ENSMUSG00000030677 0.885416501893169 0.885416501893169 0.531976482183958 0.885416501893169 0.677233817408276 0.885416501893169
Cd19 ENSMUSG00000030724 0.0276376522310474 0.0829129566931421 0.371563178558112 0.371563178558112 0.26397002162734 0.371563178558112
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Ifi30 ENSMUSG00000031838 0.136196168338928 0.408588505016783 0.362468437705198 0.543702656557797 0.635093801711498 0.635093801711498
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Crtam ENSMUSG00000032021 0.463064186093688 0.618181917795528 0.533674747735192 0.618181917795528 0.618181917795528 0.618181917795528
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Nck1 ENSMUSG00000032475 0.0975680770943668 0.2927042312831 0.522215962255415 0.683304216488649 0.683304216488649 0.683304216488649
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Lmo7 ENSMUSG00000033060 0.959080527863416 0.959080527863416 0.899497043605159 0.959080527863416 0.880788573559636 0.959080527863416
Fbxl8 ENSMUSG00000033313 0.479380961112214 0.534495897087936 0.035256707377205 0.105770122131615 0.534495897087936 0.534495897087936
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Cd226 ENSMUSG00000034028 0.663834392035331 0.740718745538522 0.432564981581081 0.740718745538522 0.740718745538522 0.740718745538522
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Kif4 ENSMUSG00000034311 0.672008419392125 0.990536313934708 0.990536313934708 0.990536313934708 0.697881022724766 0.990536313934708
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Ube2f ENSMUSG00000034343 0.00440034435439205 0.0132010330631761 0.704568606010613 0.704568606010613 0.4622914721435 0.69343720821525
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Kif15 ENSMUSG00000036768 0.443458689078018 0.870799973478293 0.870799973478293 0.870799973478293 0.770537063848605 0.870799973478293
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Icam1 ENSMUSG00000037405 0.156042056754209 0.267879632206413 0.191452306322901 0.267879632206413 0.267879632206413 0.267879632206413
H2-DMb2 ENSMUSG00000037548 0.010438990815554 0.0313169724466619 0.563934917236507 0.60479225937424 0.60479225937424 0.60479225937424
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Mylip ENSMUSG00000038175 0.548264737903629 0.797480985865397 0.797480985865397 0.797480985865397 0.658216111193869 0.797480985865397
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Cd79b ENSMUSG00000040592 0.00661659993021874 0.0198497997906562 0.461073544589017 0.461073544589017 0.220163789450436 0.330245684175654
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Rnf123 ENSMUSG00000041528 0.167767326168535 0.261537021708523 0.174358014472349 0.261537021708523 0.505363156997845 0.505363156997845
H2-Ob ENSMUSG00000041538 0.0081506452478429 0.0244519357435287 0.284266746842087 0.307687593577671 0.307687593577671 0.307687593577671
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Pilra ENSMUSG00000046245 0.45967775817636 0.68951663726454 0.849616462733731 0.849616462733731 0.133144627932194 0.399433883796583
Fbxo30 ENSMUSG00000047648 0.60646621436897 0.60646621436897 0.0912162139669631 0.273648641900889 0.508493268797473 0.60646621436897
Cd300e ENSMUSG00000048498 0.362308350224987 0.804540447752196 0.857551973977173 0.857551973977173 0.536360298501464 0.804540447752196
Amica1 ENSMUSG00000048534 0.731063619237529 0.766561034920006 0.766561034920006 0.766561034920006 0.736548171939597 0.766561034920006
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Kif18b ENSMUSG00000051378 0.699497905862386 0.89879920473075 0.175784701503063 0.527354104509188 0.89879920473075 0.89879920473075
Treml4 ENSMUSG00000051682 0.725146410326218 0.961747246857256 0.641947009095968 0.961747246857256 0.961747246857256 0.961747246857256
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Cd8b1 ENSMUSG00000053044 0.330879037014311 0.392219114476382 0.10833646019203 0.325009380576089 0.392219114476382 0.392219114476382
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Cd8a ENSMUSG00000053977 0.504862362487867 0.922516372947772 0.66842616701972 0.922516372947772 0.922516372947772 0.922516372947772
Ap1s3 ENSMUSG00000054702 0.797443459083025 0.902615530123121 0.902615530123121 0.902615530123121 0.749079742362857 0.902615530123121
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Ifitm6 ENSMUSG00000059108 0.855701602771772 0.895933675800579 0.353082934651329 0.895933675800579 0.895933675800579 0.895933675800579
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Blnk ENSMUSG00000061132 0.73126770289553 0.785332872938601 0.785332872938601 0.785332872938601 0.474594484626363 0.785332872938601
Cd300lb ENSMUSG00000063193 0.0207312822843939 0.0621938468531818 0.570511330654218 0.661128772713596 0.661128772713596 0.661128772713596
Rnf217 ENSMUSG00000063760 0.887020073445203 0.887020073445203 0.527471287724155 0.887020073445203 0.704722342205069 0.887020073445203
Hcst ENSMUSG00000064109 0.32624149620729 0.489362244310936 0.0836947710900175 0.251084313270052 0.644506547522037 0.644506547522037
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Cd300lh ENSMUSG00000069607 0.0654098325668049 0.196229497700415 0.298291561185138 0.298291561185138 0.183357512591348 0.275036268887022
Rnf213 ENSMUSG00000070327 0.918264013263851 0.918264013263851 0.707465071177749 0.918264013263851 0.388511225347229 0.918264013263851
Rasgrp3 ENSMUSG00000071042 0.874424809318059 0.874424809318059 0.322933193689276 0.484399790533914 0.316821651693806 0.484399790533914
Treml2 ENSMUSG00000071068 0.00364231313578268 0.010926939407348 0.64490120596842 0.64490120596842 0.404808766825899 0.607213150238849
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
Ccnf ENSMUSG00000072082 0.940052121072276 0.940052121072276 0.464909375449865 0.940052121072276 0.924329535381536 0.940052121072276
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379
Kifc1 ENSMUSG00000079553 0.345291705320585 0.517937557980878 0.176909636489439 0.517937557980878 0.531472280670156 0.531472280670156
Cd101 ENSMUSG00000086564 0.977724476809487 0.977724476809487 0.610102369589349 0.915153554384024 0.395129040096097 0.915153554384024
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Costimulation by the CD28 family

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Icosl ENSMUSG00000000732 0.943338320115267 0.943338320115267 0.501935949796012 0.752903924694018 0.230396936429296 0.691190809287889
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Icos ENSMUSG00000026009 0.853681624650006 0.853681624650006 0.626050536600066 0.853681624650006 0.332693462882913 0.853681624650006
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Them4 ENSMUSG00000028145 0.153778717005039 0.461336151015118 0.610465737405268 0.915698606107901 0.940224030723688 0.940224030723688
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666

TP53 Regulates Transcription of Cell Cycle Genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Btg2 ENSMUSG00000020423 0.0554709543936204 0.166412863180861 0.26451387596011 0.292776156842983 0.292776156842983 0.292776156842983
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362

Assembly of the pre-replicative complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

DNA Damage Bypass

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Usp1 ENSMUSG00000028560 0.434058003510885 0.94336484193188 0.687164372043649 0.94336484193188 0.94336484193188 0.94336484193188
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Dtl ENSMUSG00000037474 0.923090510524295 0.923090510524295 0.823872593858888 0.923090510524295 0.834219505568798 0.923090510524295
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
2810417H13Rik ENSMUSG00000040204 0.0224448522469945 0.0673345567409836 0.290970842858207 0.43645626428731 0.641283872893846 0.641283872893846
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Neutrophil degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddx3x ENSMUSG00000000787 0.0147850151108418 0.0443550453325254 0.0339581412898883 0.0509372119348325 0.803494001259412 0.803494001259412
Cfp ENSMUSG00000001128 0.943359992701168 0.943359992701168 0.731278783609124 0.943359992701168 0.130993848922794 0.392981546768381
Tcirg1 ENSMUSG00000001750 0.420108625604884 0.613126846255859 0.613126846255859 0.613126846255859 0.610507671443354 0.613126846255859
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cnn2 ENSMUSG00000004665 0.797466088347213 0.797466088347213 0.17440387844591 0.52321163533773 0.460018626332211 0.690027939498316
Man2b1 ENSMUSG00000005142 0.221379456437071 0.332069184655606 0.102898245215032 0.308694735645097 0.537551056261376 0.537551056261376
Mmp8 ENSMUSG00000005800 0.140889240722767 0.140889240722767 0.0547378998079672 0.140889240722767 0.121339068976499 0.140889240722767
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Arpc5 ENSMUSG00000008475 0.779220157100375 0.933939526638962 0.865191209261992 0.933939526638962 0.933939526638962 0.933939526638962
1810033B17Rik ENSMUSG00000013974 0.279125935039134 0.4186889025587 0.143641440000628 0.4186889025587 0.98098837440392 0.98098837440392
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Lta4h ENSMUSG00000015889 0.369628676400689 0.554443014601033 0.26639591509899 0.554443014601033 0.613289709996223 0.613289709996223
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Slpi ENSMUSG00000017002 0.525901896403392 0.788852844605089 0.883846397225027 0.883846397225027 0.377860256367586 0.788852844605089
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Ctsa ENSMUSG00000017760 0.725083813702546 0.725083813702546 0.136195903706912 0.204293855560368 0.0596331974328757 0.178899592298627
Cd68 ENSMUSG00000018774 0.0250381258104656 0.0751143774313969 0.800368254414597 0.800368254414597 0.704532079262302 0.800368254414597
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Dock2 ENSMUSG00000020143 0.158484207163789 0.462690541745841 0.534861803540552 0.534861803540552 0.308460361163894 0.462690541745841
Stk10 ENSMUSG00000020272 0.955905476444009 0.955905476444009 0.319066640368582 0.955905476444009 0.797400615427349 0.955905476444009
P2rx1 ENSMUSG00000020787 0.144555343848704 0.391238114954735 0.317040007326369 0.391238114954735 0.391238114954735 0.391238114954735
Npc2 ENSMUSG00000021242 0.436350047225227 0.654525070837841 0.809730542202457 0.809730542202457 0.3509080948472 0.654525070837841
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Nckap1l ENSMUSG00000022488 0.537557568742446 0.537557568742446 0.298327961785431 0.447491942678147 0.166647478730654 0.447491942678147
Snap29 ENSMUSG00000022765 0.130034552150217 0.39010365645065 0.529846820925724 0.779236594112805 0.779236594112805 0.779236594112805
Mmp25 ENSMUSG00000023903 0.392799211859245 0.392799211859245 0.242249676331987 0.363374514497981 0.233873028061978 0.363374514497981
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Diap1 ENSMUSG00000024456 0.687198730871812 0.927671284992682 0.38898632549416 0.927671284992682 0.927671284992682 0.927671284992682
Ostf1 ENSMUSG00000024725 0.952786629726858 0.952786629726858 0.672730855832023 0.952786629726858 0.743161159803043 0.952786629726858
Aldh3b1 ENSMUSG00000024885 0.675616471945016 0.806688380160056 0.806688380160056 0.806688380160056 0.630045600373785 0.806688380160056
Capn1 ENSMUSG00000024942 0.607656584208565 0.896377667900796 0.296447471593587 0.88934241478076 0.896377667900796 0.896377667900796
Pa2g4 ENSMUSG00000025364 0.649781268076141 0.918265286627348 0.319109697057608 0.918265286627348 0.918265286627348 0.918265286627348
Pgm2 ENSMUSG00000025791 0.580107345915472 0.794455945027837 0.266172380329822 0.794455945027837 0.794455945027837 0.794455945027837
Hk3 ENSMUSG00000025877 0.476944236414916 0.965351774163959 0.663993304822913 0.965351774163959 0.965351774163959 0.965351774163959
Slc11a1 ENSMUSG00000026177 0.00542095916779017 0.0162628775033705 0.207868305665005 0.207868305665005 0.0574547952608854 0.0861821928913281
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Ptprc ENSMUSG00000026395 0.096354079593295 0.289062238779885 0.573424410776014 0.663643080152197 0.663643080152197 0.663643080152197
Cd55 ENSMUSG00000026399 0.60500208339292 0.794461398740089 0.794461398740089 0.794461398740089 0.649785541067507 0.794461398740089
Lcn2 ENSMUSG00000026822 0.254206613494242 0.597762311676581 0.815097344133041 0.815097344133041 0.398508207784387 0.597762311676581
Fcna ENSMUSG00000026938 0.613001224980952 0.78508657962769 0.78508657962769 0.78508657962769 0.658227135226011 0.78508657962769
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Dsn1 ENSMUSG00000027635 0.834242673544129 0.908874885297229 0.615937442938951 0.908874885297229 0.908874885297229 0.908874885297229
S100a11 ENSMUSG00000027907 0.427106192169171 0.640659288253756 0.332800591805441 0.640659288253756 0.649807999096829 0.649807999096829
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Fgr ENSMUSG00000028874 0.815052467550623 0.835991601564856 0.835991601564856 0.835991601564856 0.68832951884056 0.835991601564856
Plac8 ENSMUSG00000029322 0.743101566724127 0.743101566724127 0.52209179605968 0.743101566724127 0.629965772019568 0.743101566724127
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Clec4b1 ENSMUSG00000030147 0.22922165224967 0.51305545899669 0.933532321349815 0.933532321349815 0.34203697266446 0.51305545899669
Lilra6 ENSMUSG00000030427 0.539296770535499 0.539296770535499 0.466255201605349 0.539296770535499 0.0874940183369075 0.262482055010722
Siglece ENSMUSG00000030474 0.292191785373393 0.438287678060089 0.285214487265963 0.438287678060089 0.601980510117661 0.601980510117661
Iqgap1 ENSMUSG00000030536 0.924532536222795 0.924532536222795 0.701751049467101 0.924532536222795 0.395520629042458 0.924532536222795
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Itgax ENSMUSG00000030789 0.598006607913018 0.598006607913018 0.332626450570772 0.560169820622968 0.373446547081979 0.560169820622968
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Itgal ENSMUSG00000030830 0.873556249766979 0.873556249766979 0.403755666591108 0.814534574916807 0.543023049944538 0.814534574916807
Cotl1 ENSMUSG00000031827 0.537587395147477 0.537587395147477 0.305560946064738 0.537587395147477 0.371722801509783 0.537587395147477
Ltf ENSMUSG00000032496 0.407857077827021 0.407857077827021 0.352691902770801 0.407857077827021 0.24312638437072 0.407857077827021
Cct2 ENSMUSG00000034024 0.491903194177525 0.678469807028642 0.67560413526916 0.678469807028642 0.678469807028642 0.678469807028642
Gns ENSMUSG00000034707 0.585744743221312 0.585744743221312 0.225846932859948 0.585744743221312 0.529940645351044 0.585744743221312
Eef2 ENSMUSG00000034994 0.110792657489226 0.110792657489226 0.00841680099579707 0.0252504029873912 0.106479663135253 0.110792657489226
Hpse ENSMUSG00000035273 0.834250559137513 0.993695759207487 0.993695759207487 0.993695759207487 0.210578695020539 0.631736085061617
Hmha1 ENSMUSG00000035697 0.172244269892772 0.172244269892772 0.0142213787902949 0.0426641363708846 0.0594695573239394 0.0892043359859091
Dok3 ENSMUSG00000035711 0.868318942543772 0.868318942543772 0.469517568494081 0.704276352741121 0.422301834777126 0.704276352741121
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Txndc5 ENSMUSG00000038991 0.89325623695993 0.89325623695993 0.420178502891541 0.89325623695993 0.632842448827872 0.89325623695993
Fgl2 ENSMUSG00000039899 0.53004522287058 0.779281632899727 0.604991029214678 0.779281632899727 0.779281632899727 0.779281632899727
Tbc1d10c ENSMUSG00000040247 0.0489378623710267 0.14681358711308 0.648841705947697 0.865124455501488 0.865124455501488 0.865124455501488
Arhgap9 ENSMUSG00000040345 0.25440003416661 0.692300745623403 0.609664489496356 0.692300745623403 0.692300745623403 0.692300745623403
Cd53 ENSMUSG00000040747 0.204230023552655 0.583085861213892 0.568786601077757 0.583085861213892 0.583085861213892 0.583085861213892
Serpinb1a ENSMUSG00000044734 0.955932521486043 0.955932521486043 0.90574767825056 0.955932521486043 0.629946409608427 0.955932521486043
Fpr1 ENSMUSG00000045551 0.482505456036403 0.961596937566084 0.763297093452785 0.961596937566084 0.961596937566084 0.961596937566084
Plaur ENSMUSG00000046223 0.031290111184484 0.0938703335534521 0.727998969991539 0.727998969991539 0.724909794670447 0.727998969991539
C5ar1 ENSMUSG00000049130 2.12809609905041e-05 6.38428829715122e-05 0.430872871373441 0.646309307060162 0.675020900274284 0.675020900274284
Trappc1 ENSMUSG00000049299 0.0636197260554133 0.19085917816624 0.569499074646589 0.569499074646589 0.148148319811587 0.22222247971738
Plekho2 ENSMUSG00000050721 0.125908406674103 0.377725220022309 0.661052734917824 0.661052734917824 0.530021902517946 0.661052734917824
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Cd177 ENSMUSG00000052212 0.840260674462718 0.840260674462718 0.698397279822997 0.840260674462718 0.749576335810622 0.840260674462718
Fpr2 ENSMUSG00000052270 0.422001304935369 0.940160893469069 0.940160893469069 0.940160893469069 0.937022766115294 0.940160893469069
Hbb-bs ENSMUSG00000052305 0.177918733884123 0.184202917126453 0.0954928445167644 0.184202917126453 0.184202917126453 0.184202917126453
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Ptafr ENSMUSG00000056529 0.0441827335989428 0.132548200796828 0.593971401895849 0.602122704505769 0.602122704505769 0.602122704505769
Glipr1 ENSMUSG00000056888 0.184671633933133 0.554014901799398 0.880732772529595 0.880732772529595 0.632796650542833 0.880732772529595
Slc44a2 ENSMUSG00000057193 0.209630797175147 0.389429118761442 0.259619412507628 0.389429118761442 0.583072386391489 0.583072386391489
Unc13d ENSMUSG00000057948 0.340681589288171 0.987403352398658 0.893257208399537 0.987403352398658 0.987403352398658 0.987403352398658
Nfam1 ENSMUSG00000058099 0.871059968930905 0.871059968930905 0.0371031239612186 0.111309371883656 0.141481193731918 0.212221790597878
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Pirb ENSMUSG00000058818 0.332702388332113 0.499053582498169 0.880725310592458 0.880725310592458 0.313012553202442 0.499053582498169
Fcgr4 ENSMUSG00000059089 0.837358122188999 0.837358122188999 0.71043519357456 0.837358122188999 0.834255633067832 0.837358122188999
Atp8b4 ENSMUSG00000060131 0.914606757652261 0.914606757652261 0.742671503030267 0.914606757652261 0.326925863650837 0.914606757652261
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Gmfg ENSMUSG00000060791 0.630004717252735 0.749184080834323 0.749184080834323 0.749184080834323 0.445726456417397 0.749184080834323
Prcp ENSMUSG00000061119 0.352837135755494 0.671859704909435 0.806643889978581 0.806643889978581 0.447906469939623 0.671859704909435
Efcab4b ENSMUSG00000061414 0.736077129430565 0.962120919858673 0.962120919858673 0.962120919858673 0.58373308079493 0.962120919858673
Rab44 ENSMUSG00000064147 0.240858243998035 0.240858243998035 0.139752249953515 0.215365210573624 0.143576807049083 0.215365210573624
Ano6 ENSMUSG00000064210 0.646693915422459 0.880681105629327 0.658293185525752 0.880681105629327 0.880681105629327 0.880681105629327
Hvcn1 ENSMUSG00000064267 0.521948935143001 0.77308424723638 0.77308424723638 0.77308424723638 0.596377119652557 0.77308424723638
Cpped1 ENSMUSG00000065979 0.955927933831199 0.955927933831199 0.18468407060505 0.55405221181515 0.54827981290724 0.822419719360861
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
Lyz2 ENSMUSG00000069516 0.42459148370476 0.564042324168096 0.320942239145082 0.564042324168096 0.564042324168096 0.564042324168096
Lilra5 ENSMUSG00000070873 0.855929610640207 0.855929610640207 0.471740515136299 0.855929610640207 0.840368362498668 0.855929610640207
Ear2 ENSMUSG00000072596 0.216760398415574 0.50672335410396 0.50672335410396 0.50672335410396 0.489114359644712 0.50672335410396
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
Hbb-bt ENSMUSG00000073940 0.0899400920737443 0.109415412755815 0.0351389280678127 0.105416784203438 0.109415412755815 0.109415412755815
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877
Gm14548 ENSMUSG00000074417 0.407777464874274 0.534334354372858 0.534334354372858 0.534334354372858 0.473292008332101 0.534334354372858
Sirpb1c ENSMUSG00000074677 0.579356914885657 0.869035372328486 0.283768706558931 0.851306119676793 0.984157520402225 0.984157520402225
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379
Pira2 ENSMUSG00000089942 0.490037291108727 0.735055936663091 0.870817218757294 0.870817218757294 0.390389473033881 0.735055936663091
Sirpb1b ENSMUSG00000095028 0.884834703790803 0.910771720569585 0.910771720569585 0.910771720569585 0.402516263798805 0.910771720569585
Dynlt1f ENSMUSG00000095677 0.257945480483416 0.773836441450247 0.98425720956738 0.98425720956738 0.661229284453844 0.98425720956738
Sirpb1a ENSMUSG00000095788 0.206684240616655 0.409326851364192 0.510394876146869 0.510394876146869 0.272884567576128 0.409326851364192
Dynlt1b ENSMUSG00000096255 0.292852511124036 0.810691676773085 0.965374357523301 0.965374357523301 0.540461117848723 0.810691676773085

DDX58/IFIH1-mediated induction of interferon-alpha/beta

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Chemokine receptors bind chemokines

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl3 ENSMUSG00000000982 0.0639731243372477 0.187936595794786 0.125291063863191 0.187936595794786 0.727216680497512 0.727216680497512
Ccl4 ENSMUSG00000018930 0.0682755994897608 0.204826798469282 0.537442854465909 0.537442854465909 0.221772381186438 0.332658571779656
Cxcl13 ENSMUSG00000023078 0.847824688614068 0.847824688614068 0.465616242787921 0.757486759944996 0.504991173296664 0.757486759944996
Cxcr2 ENSMUSG00000026180 0.00891434780990021 0.0267430434297006 0.171922217323729 0.257883325985594 0.804056966796032 0.804056966796032
Cxcl5 ENSMUSG00000029371 0.815956023806045 0.8501115143144 0.8501115143144 0.8501115143144 0.342800575676763 0.8501115143144
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Pf4 ENSMUSG00000029373 0.899343448384416 0.899343448384416 0.680807735581805 0.899343448384416 0.558898010233686 0.899343448384416
Cxcl9 ENSMUSG00000029417 0.811688464686606 0.836115366633473 0.753431796732797 0.836115366633473 0.836115366633473 0.836115366633473
Ccr9 ENSMUSG00000029530 0.339388545706885 0.673929254156722 0.820424128992458 0.820424128992458 0.449286169437815 0.673929254156722
Ccl22 ENSMUSG00000031779 0.412987362875792 0.592159046903127 0.592159046903127 0.592159046903127 0.277068969370578 0.592159046903127
Cxcl10 ENSMUSG00000034855 0.82806707470646 0.82806707470646 0.554933409626777 0.82806707470646 0.518516603829129 0.82806707470646
Ccl5 ENSMUSG00000035042 0.501400526611382 0.501400526611382 0.153023348201387 0.459070044604161 0.478552279679389 0.501400526611382
Ccr3 ENSMUSG00000035448 0.565433621119064 0.848150431678596 0.522888199532518 0.848150431678596 0.987158510729074 0.987158510729074
Ccr7 ENSMUSG00000037944 0.255828981012523 0.767486943037568 0.808004745303223 0.808004745303223 0.784519651620392 0.808004745303223
Ccr10 ENSMUSG00000044052 0.417964769369981 0.521910427444515 0.0994658181085909 0.298397454325773 0.521910427444515 0.521910427444515
Ackr2 ENSMUSG00000044534 0.684038182283277 0.806532042195151 0.806532042195151 0.806532042195151 0.109183970971895 0.327551912915684
Cxcr5 ENSMUSG00000047880 0.0685983316225568 0.20579499486767 0.268231649719138 0.268231649719138 0.157837100857088 0.236755651285632
Cxcr6 ENSMUSG00000048521 0.715643112937345 0.744313865805145 0.744313865805145 0.744313865805145 0.547904801202565 0.744313865805145
Cxcr3 ENSMUSG00000050232 0.864236852727334 0.864236852727334 0.854989491303756 0.864236852727334 0.346629814669672 0.864236852727334
Xcr1 ENSMUSG00000060509 0.97100348220911 0.97100348220911 0.562621752231069 0.843932628346603 0.403342929285652 0.843932628346603
Cxcl12 ENSMUSG00000061353 0.849643364011985 0.849643364011985 0.178130890673705 0.295229890416715 0.196819926944476 0.295229890416715
Ccl19 ENSMUSG00000071005 0.313038616853503 0.469557925280254 0.64409568095133 0.64409568095133 0.227268305163348 0.469557925280254
Ccr5 ENSMUSG00000079227 0.00289155498134552 0.00867466494403657 0.632194479448918 0.632194479448918 0.152498992615402 0.228748488923103
Ccl21a ENSMUSG00000094686 0.974775224406031 0.974775224406031 0.769761860735048 0.974775224406031 0.946418907773685 0.974775224406031

Polymerase switching on the C-strand of the telomere

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Recognition of DNA damage by PCNA-containing replication complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Usp1 ENSMUSG00000028560 0.434058003510885 0.94336484193188 0.687164372043649 0.94336484193188 0.94336484193188 0.94336484193188
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Dtl ENSMUSG00000037474 0.923090510524295 0.923090510524295 0.823872593858888 0.923090510524295 0.834219505568798 0.923090510524295
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Orc1 removal from chromatin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll-like Receptor Cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ly86 ENSMUSG00000021423 0.48934816007253 0.734022240108795 0.981104321793152 0.981104321793152 0.303929321183376 0.734022240108795
Cd180 ENSMUSG00000021624 0.996835241156126 0.996835241156126 0.955927560068442 0.996835241156126 0.990511138945618 0.996835241156126
Ctsb ENSMUSG00000021939 0.447889333645271 0.447889333645271 0.100642355508025 0.301927066524074 0.305454038005978 0.447889333645271
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ctss ENSMUSG00000038642 0.484343908770736 0.713429869318064 0.713429869318064 0.713429869318064 0.350648392102665 0.713429869318064
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Tlr8 ENSMUSG00000040522 0.276415018975345 0.719738315372709 0.675774856914558 0.719738315372709 0.719738315372709 0.719738315372709
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

PD-1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cd3g ENSMUSG00000002033 0.653313194879145 0.653313194879145 0.552777561894529 0.653313194879145 0.444287622561961 0.653313194879145
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Cd247 ENSMUSG00000005763 0.0645706803771399 0.19371204113142 0.323818693597302 0.485728040395952 0.55113576819405 0.55113576819405
Cd274 ENSMUSG00000016496 0.539980976350288 0.78523008620953 0.78523008620953 0.78523008620953 0.125294567289895 0.375883701869685
Cd4 ENSMUSG00000023274 0.137425597667415 0.412276793002244 0.897892804710942 0.897892804710942 0.402031535455218 0.603047303182827
Cd3e ENSMUSG00000032093 0.751830470673598 0.928806077818302 0.928806077818302 0.928806077818302 0.733294744218016 0.928806077818302
Cd3d ENSMUSG00000032094 0.272754217468795 0.766341705409648 0.766341705409648 0.766341705409648 0.656207128862334 0.766341705409648
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
H2-Eb2 ENSMUSG00000067341 0.112015883484395 0.336047650453184 0.50965598979876 0.50965598979876 0.504690593729139 0.50965598979876
Trbc1 ENSMUSG00000076490 0.328524867166172 0.492787300749259 0.304369411081792 0.492787300749259 0.732226871834306 0.732226871834306
Trbc2 ENSMUSG00000076498 0.755084733537726 0.755084733537726 0.371316683268863 0.755084733537726 0.675491947155486 0.755084733537726
Trac ENSMUSG00000076928 0.901982017359671 0.924093477923666 0.924093477923666 0.924093477923666 0.590525061011764 0.924093477923666

Regulation of TP53 Activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Ing5 ENSMUSG00000026283 0.216953769437519 0.650861308312557 0.758176120614944 0.758176120614944 0.524849995102513 0.758176120614944
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Brd7 ENSMUSG00000031660 0.274643819833046 0.823931459499138 0.918252686805685 0.918252686805685 0.794427053313234 0.918252686805685
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Gatad2a ENSMUSG00000036180 0.862120369682674 0.933946371176347 0.484424763284525 0.933946371176347 0.933946371176347 0.933946371176347
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Mta2 ENSMUSG00000071646 0.871439535891264 0.871439535891264 0.80053481253197 0.871439535891264 0.710463049196743 0.871439535891264
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Processing of DNA double-strand break ends

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Ppp4c ENSMUSG00000030697 0.0592125528199272 0.0888188292298908 0.0405678931068457 0.0888188292298908 0.543076952932224 0.543076952932224
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Tipin ENSMUSG00000032397 0.167415262600935 0.502245787802805 0.596543418981314 0.894815128471971 0.946411756114403 0.946411756114403
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Timeless ENSMUSG00000039994 0.862002146024331 0.862002146024331 0.44108597923605 0.711344769384679 0.474229846256453 0.711344769384679
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406

PCNA-Dependent Long Patch Base Excision Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Activation of NF-kappaB in B cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

GPVI-mediated activation cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Clec1b ENSMUSG00000030159 0.109815078009729 0.329445234029186 0.905662764674105 0.905662764674105 0.452311992223792 0.678467988335688
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
AU023871 ENSMUSG00000073414 0.244052682708912 0.721710295011787 0.640487037391299 0.721710295011787 0.721710295011787 0.721710295011787
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877

Dual Incision in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Chd1l ENSMUSG00000028089 0.698783983895017 0.698783983895017 0.233694116682994 0.698783983895017 0.646931914948733 0.698783983895017
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Switching of origins to a post-replicative state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Mcm2 ENSMUSG00000002870 0.50221180235383 0.753317703530745 0.422159272894584 0.753317703530745 0.927288384821729 0.927288384821729
Mcm5 ENSMUSG00000005410 0.996847874137369 0.996847874137369 0.76412906892118 0.996847874137369 0.971636750611246 0.996847874137369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Mcm4 ENSMUSG00000022673 0.7461523218274 0.7461523218274 0.340783118419547 0.7461523218274 0.630014050044505 0.7461523218274
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Mcm6 ENSMUSG00000026355 0.843449579281452 0.843449579281452 0.75216822803506 0.843449579281452 0.615746518398812 0.843449579281452
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mcm7 ENSMUSG00000029730 0.348194639636319 0.635643169175244 0.635643169175244 0.635643169175244 0.609949855607885 0.635643169175244
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Mcm3 ENSMUSG00000041859 0.939719040052603 0.939719040052603 0.532172729786363 0.939719040052603 0.667063505436864 0.939719040052603
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

G2/M DNA damage checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Fam175a ENSMUSG00000035234 0.644062204016168 0.644062204016168 0.41765418456774 0.626481276851609 0.417570581940392 0.626481276851609
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406

Transcriptional Regulation by TP53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Btg2 ENSMUSG00000020423 0.0554709543936204 0.166412863180861 0.26451387596011 0.292776156842983 0.292776156842983 0.292776156842983
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Supt4a ENSMUSG00000020485 0.0625058326488859 0.187517497946658 0.489393978487283 0.489393978487283 0.388971088371462 0.489393978487283
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Bnip3l ENSMUSG00000022051 0.157549939428809 0.236324909143213 0.110803282596096 0.236324909143213 0.273922096860272 0.273922096860272
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Cox7a2l ENSMUSG00000024248 0.843550103789667 0.843550103789667 0.713543280357916 0.843550103789667 0.604951121583963 0.843550103789667
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Ing5 ENSMUSG00000026283 0.216953769437519 0.650861308312557 0.758176120614944 0.758176120614944 0.524849995102513 0.758176120614944
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Tceb3 ENSMUSG00000028668 0.254372038202086 0.678506158806887 0.602190822724916 0.678506158806887 0.678506158806887 0.678506158806887
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Triap1 ENSMUSG00000029535 0.0374929148817493 0.112478744645248 0.227409298159885 0.341113947239827 0.457622343285298 0.457622343285298
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Brd7 ENSMUSG00000031660 0.274643819833046 0.823931459499138 0.918252686805685 0.918252686805685 0.794427053313234 0.918252686805685
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Gatad2a ENSMUSG00000036180 0.862120369682674 0.933946371176347 0.484424763284525 0.933946371176347 0.933946371176347 0.933946371176347
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cox19 ENSMUSG00000045438 0.630020093033922 0.66409928319106 0.66409928319106 0.66409928319106 0.344805790981147 0.66409928319106
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Mta2 ENSMUSG00000071646 0.871439535891264 0.871439535891264 0.80053481253197 0.871439535891264 0.710463049196743 0.871439535891264
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

CLEC7A (Dectin-1) signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Clec7a ENSMUSG00000079293 0.588455398912374 0.882683098368562 0.987388713171692 0.987388713171692 0.263796829802785 0.791390489408355
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Resolution of AP sites via the multiple-nucleotide patch replacement pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

G1/S DNA Damage Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804

Toll Like Receptor 4 (TLR4) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ly86 ENSMUSG00000021423 0.48934816007253 0.734022240108795 0.981104321793152 0.981104321793152 0.303929321183376 0.734022240108795
Cd180 ENSMUSG00000021624 0.996835241156126 0.996835241156126 0.955927560068442 0.996835241156126 0.990511138945618 0.996835241156126
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Dnm2 ENSMUSG00000033335 0.82815431228593 0.840470291564236 0.607741508735074 0.840470291564236 0.840470291564236 0.840470291564236
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Processive synthesis on the lagging strand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Removal of the Flap Intermediate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Mitotic G2-G2/M phases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Hmmr ENSMUSG00000020330 0.50429506937531 0.756442604062965 0.861393672414444 0.861393672414444 0.297159974312533 0.756442604062965
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Bora ENSMUSG00000022070 0.440766423606727 0.830081346867545 0.84043263187544 0.84043263187544 0.553387564578363 0.830081346867545
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

G2/M Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Hmmr ENSMUSG00000020330 0.50429506937531 0.756442604062965 0.861393672414444 0.861393672414444 0.297159974312533 0.756442604062965
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Bora ENSMUSG00000022070 0.440766423606727 0.830081346867545 0.84043263187544 0.84043263187544 0.553387564578363 0.830081346867545
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Resolution of Abasic Sites (AP sites)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Mutyh ENSMUSG00000028687 0.574867504158502 0.77019634576434 0.77019634576434 0.77019634576434 0.664040896456067 0.77019634576434
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Ogg1 ENSMUSG00000030271 0.0442716123757612 0.132814837127284 0.438688139246743 0.658032208870115 0.734226035946159 0.734226035946159
Neil1 ENSMUSG00000032298 0.552851047579205 0.829276571368808 0.388947726176355 0.829276571368808 0.830863465675073 0.830863465675073
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TAK1 activates NFkB by phosphorylation and activation of IKKs complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TRIF(TICAM1)-mediated TLR4 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

MyD88-independent TLR4 cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p53-Dependent G1 DNA Damage Response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p53-Dependent G1/S DNA damage checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mismatch Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038

Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Msh6 ENSMUSG00000005370 0.977956801024508 0.977956801024508 0.764176471372125 0.977956801024508 0.868336793071681 0.977956801024508
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Mlh1 ENSMUSG00000032498 0.862099845459909 0.862099845459909 0.46008940379012 0.69013410568518 0.378151050647303 0.69013410568518
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

ZBP1(DAI) mediated induction of type I IFNs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524

Dual incision in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Zfp830 ENSMUSG00000046010 0.574968999682525 0.831211863248003 0.481959295162291 0.831211863248003 0.831211863248003 0.831211863248003
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Dectin-2 family

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Clec4n ENSMUSG00000023349 0.66366094094944 0.911880328065958 0.911880328065958 0.911880328065958 0.788291202279061 0.911880328065958
Clec4e ENSMUSG00000030142 0.0590533162577188 0.177159948773157 0.963596399582816 0.966712119093552 0.966712119093552 0.966712119093552
Clec4d ENSMUSG00000030144 0.0716149026722676 0.214844708016803 0.993409801098939 0.993409801098939 0.934728313009645 0.993409801098939
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641

Downstream signaling events of B Cell Receptor (BCR)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Nfkbie ENSMUSG00000023947 0.143491000264636 0.320334398102611 0.21355626540174 0.320334398102611 0.672424103659048 0.672424103659048
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Bcl10 ENSMUSG00000028191 0.264570484946806 0.396855727420208 0.0949113870780096 0.284734161234029 0.681365041985284 0.681365041985284
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Malt1 ENSMUSG00000032688 0.815726901814316 0.815726901814316 0.514382537311636 0.815726901814316 0.695631341577042 0.815726901814316
Card11 ENSMUSG00000036526 0.363578798859213 0.900174686008897 0.871617435573068 0.900174686008897 0.900174686008897 0.900174686008897
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Rasgrp3 ENSMUSG00000071042 0.874424809318059 0.874424809318059 0.322933193689276 0.484399790533914 0.316821651693806 0.484399790533914
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cytosolic sensors of pathogen-associated DNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Tmem173 ENSMUSG00000024349 0.063586636150033 0.190759908450099 0.413223756640367 0.413223756640367 0.147714566978938 0.221571850468408
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Translesion Synthesis by POLH

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Polh ENSMUSG00000023953 0.637864231389744 0.733647550201515 0.216872894449284 0.650618683347853 0.733647550201515 0.733647550201515
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rchy1 ENSMUSG00000029397 0.0780768303431987 0.234230491029596 0.251318098528154 0.376977147792231 0.588537687756264 0.588537687756264
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Tank ENSMUSG00000064289 0.189845136071365 0.357418232065379 0.238278821376919 0.357418232065379 0.686938573952162 0.686938573952162
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll Like Receptor 7/8 (TLR7/8) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Tlr7 ENSMUSG00000044583 0.00180837028465158 0.00542511085395473 0.624036871885665 0.769973506140994 0.769973506140994 0.769973506140994
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Nucleosome assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Mis18a ENSMUSG00000022978 0.981109162888008 0.981109162888008 0.877663099932883 0.981109162888008 0.561547563685078 0.981109162888008
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Mis18bp1 ENSMUSG00000047534 0.451294432983342 0.676941649475013 0.870765548937771 0.870765548937771 0.442816310918232 0.676941649475013
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Oip5 ENSMUSG00000072980 0.879701243029315 0.930060290012718 0.428937086467369 0.930060290012718 0.930060290012718 0.930060290012718
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Cenpw ENSMUSG00000075266 0.582559292756862 0.582559292756862 0.361196903438474 0.582559292756862 0.558383067549043 0.582559292756862

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Tfam ENSMUSG00000003923 0.193911845162258 0.581735535486775 0.965364099944801 0.981099367157704 0.981099367157704 0.981099367157704
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Ddx39 ENSMUSG00000005481 0.266365938779284 0.532596299455637 0.369580486206305 0.532596299455637 0.532596299455637 0.532596299455637
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Med8 ENSMUSG00000006392 0.256090699944685 0.373810541935696 0.0917016487295043 0.275104946188513 0.373810541935696 0.373810541935696
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pax5 ENSMUSG00000014030 0.0186093555017439 0.0558280665052318 0.204974322565396 0.307461483848093 0.657838226196952 0.657838226196952
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Suz12 ENSMUSG00000017548 0.862131725733286 0.930805877637186 0.91826375858401 0.930805877637186 0.930805877637186 0.930805877637186
Myo1c ENSMUSG00000017774 0.770207197610339 0.770207197610339 0.436310308243349 0.654465462365024 0.249676321659711 0.654465462365024
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Gtf3c6 ENSMUSG00000019837 0.0538131185530085 0.161439355659025 0.178217533544542 0.267326300316814 0.593771002533249 0.593771002533249
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Sirt1 ENSMUSG00000020063 0.791414478789436 0.915141605502986 0.831202801623218 0.915141605502986 0.915141605502986 0.915141605502986
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Btg2 ENSMUSG00000020423 0.0554709543936204 0.166412863180861 0.26451387596011 0.292776156842983 0.292776156842983 0.292776156842983
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Zkscan17 ENSMUSG00000020472 0.104824971366656 0.314474914099968 0.289092354244328 0.433638531366492 0.981108384766924 0.981108384766924
Supt4a ENSMUSG00000020485 0.0625058326488859 0.187517497946658 0.489393978487283 0.489393978487283 0.388971088371462 0.489393978487283
Twistnb ENSMUSG00000020561 0.340750181790478 0.511125272685717 0.169426094457558 0.508278283372674 0.86831174199068 0.86831174199068
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Nr1d1 ENSMUSG00000020889 0.037729783244716 0.113189349734148 0.209157490340506 0.209157490340506 0.0793152933452557 0.118972940017884
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Zfp839 ENSMUSG00000021271 0.282068891127281 0.436389799105874 0.29092653273725 0.436389799105874 0.865223184872352 0.865223184872352
Dek ENSMUSG00000021377 0.479308398166014 0.987399328842821 0.664102629729157 0.987399328842821 0.987399328842821 0.987399328842821
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Thrb ENSMUSG00000021779 0.908867691330257 0.908867691330257 0.707634351389092 0.908867691330257 0.785360984244778 0.908867691330257
Eaf1 ENSMUSG00000021890 0.88701835685625 0.88701835685625 0.132127787715956 0.396383363147867 0.752171520997964 0.88701835685625
Bnip3l ENSMUSG00000022051 0.157549939428809 0.236324909143213 0.110803282596096 0.236324909143213 0.273922096860272 0.273922096860272
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Atad2 ENSMUSG00000022360 0.352970992971963 0.798918026870966 0.840429237325643 0.840429237325643 0.532612017913977 0.798918026870966
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Zfp54 ENSMUSG00000023882 0.107398467562758 0.322195402688274 0.280311939376316 0.420467909064474 0.580367987289222 0.580367987289222
Zfp51 ENSMUSG00000023892 0.235190921747482 0.352786382621223 0.117196972981545 0.351590918944635 0.874462752666159 0.874462752666159
Cox7a2l ENSMUSG00000024248 0.843550103789667 0.843550103789667 0.713543280357916 0.843550103789667 0.604951121583963 0.843550103789667
Brd2 ENSMUSG00000024335 0.962223160725627 0.962223160725627 0.684299459384187 0.962223160725627 0.940221045852158 0.962223160725627
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Sirt3 ENSMUSG00000025486 0.136198946966682 0.225673657746083 0.150449105164055 0.225673657746083 0.371654935689413 0.371654935689413
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Smad7 ENSMUSG00000025880 0.649798395621747 0.896376264313015 0.761168517994278 0.896376264313015 0.896376264313015 0.896376264313015
Ing5 ENSMUSG00000026283 0.216953769437519 0.650861308312557 0.758176120614944 0.758176120614944 0.524849995102513 0.758176120614944
Esrrg ENSMUSG00000026610 0.672477722339562 0.698745137865805 0.658248858042778 0.698745137865805 0.698745137865805 0.698745137865805
Phf19 ENSMUSG00000026873 0.35021090428612 0.52531635642918 0.585279720996408 0.585279720996408 0.196771022979305 0.52531635642918
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Ell3 ENSMUSG00000027246 0.92662721405129 0.92662721405129 0.596962483768408 0.895443725652613 0.575873236417166 0.895443725652613
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Dnmt3b ENSMUSG00000027478 0.264153521975037 0.396230282962556 0.740148992591262 0.740148992591262 0.0330573727406786 0.0991721182220359
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Polr3c ENSMUSG00000028099 0.716446378602089 0.716446378602089 0.669791711571956 0.716446378602089 0.550773488885218 0.716446378602089
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Polr1e ENSMUSG00000028318 0.649762019419188 0.852822858033419 0.535227950200136 0.852822858033419 0.852822858033419 0.852822858033419
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Tceb3 ENSMUSG00000028668 0.254372038202086 0.678506158806887 0.602190822724916 0.678506158806887 0.678506158806887 0.678506158806887
Tal1 ENSMUSG00000028717 0.803181825280339 0.803181825280339 0.324702995622202 0.803181825280339 0.687158429096566 0.803181825280339
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Ran ENSMUSG00000029430 0.269488170230897 0.452051560422775 0.301367706948516 0.452051560422775 0.933904431547453 0.933904431547453
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Triap1 ENSMUSG00000029535 0.0374929148817493 0.112478744645248 0.227409298159885 0.341113947239827 0.457622343285298 0.457622343285298
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Zkscan14 ENSMUSG00000029627 0.877667464192645 0.984256935420092 0.880780791763657 0.984256935420092 0.984256935420092 0.984256935420092
Ezh2 ENSMUSG00000029687 0.782286313415417 0.87142225389964 0.393342680501779 0.87142225389964 0.87142225389964 0.87142225389964
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Eed ENSMUSG00000030619 0.0559764036544124 0.167929210963237 0.268006841635886 0.402010262453828 0.746093866961244 0.746093866961244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Sin3b ENSMUSG00000031622 0.952733639892361 0.952733639892361 0.511491664615441 0.952733639892361 0.731275407599301 0.952733639892361
Brd7 ENSMUSG00000031660 0.274643819833046 0.823931459499138 0.918252686805685 0.918252686805685 0.794427053313234 0.918252686805685
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Taf1d ENSMUSG00000031939 0.148116238452801 0.43659102587211 0.29106068391474 0.43659102587211 0.865211912487404 0.865211912487404
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Narg2 ENSMUSG00000032235 0.646948389636692 0.646948389636692 0.632831086366631 0.646948389636692 0.369536146110138 0.646948389636692
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Lmo2 ENSMUSG00000032698 0.433970192533923 0.433970192533923 0.169427628688144 0.27104776367791 0.180698509118606 0.27104776367791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Gtf2a2 ENSMUSG00000033543 0.591199025129356 0.621633440166777 0.621633440166777 0.621633440166777 0.426999601237835 0.621633440166777
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Vwa9 ENSMUSG00000034263 0.219698463359575 0.523033974968959 0.348689316645973 0.523033974968959 0.585594747924523 0.585594747924523
Med13 ENSMUSG00000034297 0.0701811382578752 0.210543414773626 0.357093837699953 0.53564075654993 0.977957839634294 0.977957839634294
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Polr3b ENSMUSG00000034453 0.788393174127829 0.92140590417822 0.92140590417822 0.92140590417822 0.846654855910342 0.92140590417822
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Polr3g ENSMUSG00000035834 0.0641125140282136 0.192337542084641 0.84973061480391 0.84973061480391 0.767089226979462 0.84973061480391
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Gatad2a ENSMUSG00000036180 0.862120369682674 0.933946371176347 0.484424763284525 0.933946371176347 0.933946371176347 0.933946371176347
Znrd1 ENSMUSG00000036315 0.0821378908948957 0.246413672684687 0.203887954519348 0.305831931779022 0.32102217702293 0.32102217702293
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Elf1 ENSMUSG00000036461 0.740193790947836 0.740193790947836 0.740174990210497 0.740193790947836 0.599460938221545 0.740193790947836
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Zfp113 ENSMUSG00000037007 0.48198061459868 0.722970921898021 0.764154844671624 0.764154844671624 0.174287827316986 0.522863481950959
Elf2 ENSMUSG00000037174 0.843511612134173 0.843511612134173 0.402086839746097 0.843511612134173 0.627112152298218 0.843511612134173
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Smarce1 ENSMUSG00000037935 0.773237987055144 0.952793633147213 0.952793633147213 0.952793633147213 0.722394347727836 0.952793633147213
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Foxp3 ENSMUSG00000039521 0.82048901146847 0.989694584991145 0.86553259272103 0.989694584991145 0.989694584991145 0.989694584991145
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Thoc6 ENSMUSG00000041319 0.658299158938436 0.725211259395702 0.725211259395702 0.725211259395702 0.316993797124339 0.725211259395702
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cox19 ENSMUSG00000045438 0.630020093033922 0.66409928319106 0.66409928319106 0.66409928319106 0.344805790981147 0.66409928319106
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Zfp710 ENSMUSG00000048897 0.564184858845317 0.846277288267975 0.486900237975711 0.846277288267975 1 1
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Maml1 ENSMUSG00000050567 0.849727679593125 0.849727679593125 0.818911566463586 0.849727679593125 0.834281670694547 0.849727679593125
Zfp455 ENSMUSG00000051037 0.764022731411663 0.85893458048499 0.474566507719613 0.85893458048499 0.85893458048499 0.85893458048499
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Zfp52 ENSMUSG00000051341 0.78829254223511 0.78829254223511 0.440981173924791 0.78829254223511 0.687060498605718 0.78829254223511
Prdm9 ENSMUSG00000051977 0.905727726614082 0.905727726614082 0.524861443088293 0.78729216463244 0.166927746811478 0.500783240434435
Zfp472 ENSMUSG00000053600 0.287402210782007 0.86220663234602 0.88697555467567 0.88697555467567 0.755089264429628 0.88697555467567
AI987944 ENSMUSG00000056383 0.046943389408073 0.083212566418127 0.0554750442787513 0.083212566418127 0.408216767392623 0.408216767392623
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Zfp53 ENSMUSG00000057409 0.596604814915064 0.855859911520181 0.855859911520181 0.855859911520181 0.791279357193469 0.855859911520181
Zfp595 ENSMUSG00000057842 0.122808665645878 0.368425996937634 0.484265413652523 0.726398120478784 0.727900911027923 0.727900911027923
Rsl1 ENSMUSG00000058900 0.0584419490614589 0.175325847184377 0.849689489598832 0.849689489598832 0.54276353235559 0.814145298533385
Zfp945 ENSMUSG00000059142 0.340478721846338 0.378165145753242 0.176602125959318 0.378165145753242 0.378165145753242 0.378165145753242
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Nr1h2 ENSMUSG00000060601 0.56147429589878 0.56147429589878 0.415654486437077 0.56147429589878 0.530007595823729 0.56147429589878
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Tgif2 ENSMUSG00000062175 0.0239283787827764 0.0717851363483292 0.716395803810444 0.758140057113732 0.758140057113732 0.758140057113732
Zfp677 ENSMUSG00000062743 0.50693304889277 0.50693304889277 0.365429855786619 0.50693304889277 0.354988555585396 0.50693304889277
Hdac10 ENSMUSG00000062906 0.0438411444736475 0.131523433420942 0.315215322517597 0.315215322517597 0.187244659337631 0.280866989006447
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Zfp69 ENSMUSG00000064141 0.800392829713434 0.974789757595072 0.974789757595072 0.974789757595072 0.758158038538366 0.974789757595072
Polr1c ENSMUSG00000067148 0.519748758068391 0.63849341200239 0.594003694054131 0.63849341200239 0.63849341200239 0.63849341200239
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
Mta2 ENSMUSG00000071646 0.871439535891264 0.871439535891264 0.80053481253197 0.871439535891264 0.710463049196743 0.871439535891264
4930522L14Rik ENSMUSG00000072762 0.704436857185727 0.877542736319083 0.698593453067751 0.877542736319083 0.877542736319083 0.877542736319083
5430403G16Rik ENSMUSG00000072763 0.737150506589246 0.971657617996358 0.346767950477885 0.971657617996358 0.971657617996358 0.971657617996358
Gm21994 ENSMUSG00000074735 0.43771368652445 0.43771368652445 0.230077923702433 0.43771368652445 0.403517247683641 0.43771368652445
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Sarnp ENSMUSG00000078427 0.129072399107977 0.273145551583203 0.182097034388802 0.273145551583203 0.918249374405348 0.918249374405348
Gm13212 ENSMUSG00000078502 0.459121900778597 0.614422682067283 0.0193616841614488 0.0580850524843463 0.614422682067283 0.614422682067283
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Smarcd2 ENSMUSG00000078619 0.725323748108241 0.773235770097311 0.773235770097311 0.773235770097311 0.496882397396578 0.773235770097311
Zfp429 ENSMUSG00000078994 0.189623757130002 0.568871271390006 0.596748154975984 0.596748154975984 0.476549702044465 0.596748154975984
Zfp456 ENSMUSG00000078995 0.13010991999385 0.39032975998155 0.499411678679109 0.718043510024566 0.718043510024566 0.718043510024566
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Med12 ENSMUSG00000079487 0.527431304067025 0.527431304067025 0.457666072739171 0.527431304067025 0.438728761719674 0.527431304067025
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Zfp97 ENSMUSG00000095990 0.266401009134915 0.399601513702372 0.254521957181761 0.399601513702372 0.479504814652902 0.479504814652902
Zfp433 ENSMUSG00000096795 0.249587181016902 0.444687616335941 0.296458410890627 0.444687616335941 0.710577880375194 0.710577880375194

Deposition of new CENPA-containing nucleosomes at the centromere

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cenpo ENSMUSG00000020652 0.472028290227296 0.708042435340944 0.424738148085002 0.708042435340944 0.899477737446515 0.899477737446515
Cenpp ENSMUSG00000021391 0.358880364589078 0.928181612585254 0.618787741723503 0.928181612585254 0.990510421623212 0.990510421623212
Cenpk ENSMUSG00000021714 0.977623008855812 0.977623008855812 0.61272328899979 0.977623008855812 0.971248798186813 0.977623008855812
Mis18a ENSMUSG00000022978 0.981109162888008 0.981109162888008 0.877663099932883 0.981109162888008 0.561547563685078 0.981109162888008
Cenpq ENSMUSG00000023919 0.893212909860434 0.893212909860434 0.564140979956449 0.893212909860434 0.749067409258338 0.893212909860434
Cenpl ENSMUSG00000026708 0.868169398279845 0.993695523620077 0.858992593219996 0.993695523620077 0.993695523620077 0.993695523620077
Casc5 ENSMUSG00000027326 0.486401079117696 0.486401079117696 0.463765429461808 0.486401079117696 0.299587527737645 0.486401079117696
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Cenpa ENSMUSG00000029177 0.724485170138 0.806037173004011 0.188565267912637 0.565695803737911 0.806037173004011 0.806037173004011
Cenpi ENSMUSG00000031262 0.423100953837125 0.733947711111391 0.733947711111391 0.733947711111391 0.541497081627008 0.733947711111391
Mlf1ip ENSMUSG00000031629 0.773184589570577 0.794430645797821 0.737197286896491 0.794430645797821 0.794430645797821 0.794430645797821
Cenpn ENSMUSG00000031756 0.272495493707328 0.817486481121985 0.745933278352602 0.955513894962097 0.955513894962097 0.955513894962097
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Cenph ENSMUSG00000045273 0.625183705882355 0.914896718149248 0.914896718149248 0.914896718149248 0.726726790970081 0.914896718149248
Mis18bp1 ENSMUSG00000047534 0.451294432983342 0.676941649475013 0.870765548937771 0.870765548937771 0.442816310918232 0.676941649475013
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Cenpm ENSMUSG00000068101 0.927653003249546 0.927653003249546 0.737173192782211 0.927653003249546 0.558895329215965 0.927653003249546
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Oip5 ENSMUSG00000072980 0.879701243029315 0.930060290012718 0.428937086467369 0.930060290012718 0.930060290012718 0.930060290012718
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Cenpw ENSMUSG00000075266 0.582559292756862 0.582559292756862 0.361196903438474 0.582559292756862 0.558383067549043 0.582559292756862

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p53-Independent DNA Damage Response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p53-Independent G1/S DNA damage checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Telomere Maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Dscc1 ENSMUSG00000022422 0.93007089718159 0.93007089718159 0.637763677609459 0.93007089718159 0.494175521685197 0.93007089718159
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Ppp6r3 ENSMUSG00000024908 0.725285226401555 0.776262387276821 0.43158823472778 0.776262387276821 0.776262387276821 0.776262387276821
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267
Nop10 ENSMUSG00000027133 0.433963194739969 0.585808307031612 0.585808307031612 0.585808307031612 0.251190405158169 0.585808307031612
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Shq1 ENSMUSG00000035378 0.693023808714369 0.693023808714369 0.156197266551862 0.355252234363206 0.236834822908804 0.355252234363206
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Pif1 ENSMUSG00000041064 0.778619210639809 0.942399990559268 0.942399990559268 0.942399990559268 0.808405022155022 0.942399990559268
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406

Gap-filling DNA repair synthesis and ligation in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Zfp830 ENSMUSG00000046010 0.574968999682525 0.831211863248003 0.481959295162291 0.831211863248003 0.831211863248003 0.831211863248003
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TNFs bind their physiological receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Edar ENSMUSG00000003227 0.000514803959971619 0.00154441187991486 0.745938933608556 0.745938933608556 0.305490022868052 0.458235034302077
Tnfrsf13b ENSMUSG00000010142 0.858844573031321 0.858844573031321 0.414604557132728 0.809973099424211 0.539982066282808 0.809973099424211
Tnfrsf17 ENSMUSG00000022496 0.141205084488452 0.423615253465355 0.573515650998747 0.86027347649812 0.871500707864625 0.871500707864625
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Tnfsf8 ENSMUSG00000028362 0.572378473457636 0.585516979927963 0.535638996314391 0.585516979927963 0.585516979927963 0.585516979927963
Tnfrsf1b ENSMUSG00000028599 0.208154465264331 0.316973282900196 0.238158324547125 0.316973282900196 0.316973282900196 0.316973282900196
Tnfrsf9 ENSMUSG00000028965 0.551979116404505 0.849045304877206 0.778404727857629 0.849045304877206 0.849045304877206 0.849045304877206
Cd27 ENSMUSG00000030336 0.63681419423859 0.855166267900634 0.855166267900634 0.855166267900634 0.426478775983714 0.855166267900634
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Tnfsf9 ENSMUSG00000035678 0.868119017145407 0.930773105897805 0.930773105897805 0.930773105897805 0.352566427942107 0.930773105897805
Tnfrsf18 ENSMUSG00000041954 0.565886325135964 0.848829487703946 0.398530238309786 0.848829487703946 0.93922116070972 0.93922116070972
Tnfrsf14 ENSMUSG00000042333 0.596729533067793 0.65821553848778 0.65821553848778 0.65821553848778 0.271419435256925 0.65821553848778

SCF(Skp2)-mediated degradation of p27/p21

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

MyD88 dependent cascade initiated on endosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

RIP-mediated NFkB activation via ZBP1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524

Toll Like Receptor 9 (TLR9) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Tlr9 ENSMUSG00000045322 0.194727340570546 0.292091010855819 0.974810870669259 0.974810870669259 0.121698261185187 0.292091010855819
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Interferon Signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Ifngr1 ENSMUSG00000020009 0.638373334051427 0.785317011606272 0.785317011606272 0.785317011606272 0.311390038602004 0.785317011606272
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Ptpn2 ENSMUSG00000024539 0.298364682060503 0.469750527970165 0.391161952011083 0.469750527970165 0.469750527970165 0.469750527970165
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Pde12 ENSMUSG00000043702 0.073424105599251 0.220272316797753 0.962224737253253 0.981105309298905 0.981105309298905 0.981105309298905
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142

Cyclin E associated events during G1/S transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Antigen processing-Cross presentation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Cybb ENSMUSG00000015340 0.990546852868618 0.990546852868618 0.403998124881834 0.990546852868618 0.905711695351853 0.990546852868618
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Ncf1 ENSMUSG00000015950 0.200618340050669 0.200618340050669 0.17434711671173 0.200618340050669 0.176573971733193 0.200618340050669
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Tapbp ENSMUSG00000024308 0.16933853725879 0.254007805888185 0.139422104921692 0.254007805888185 0.543071451930669 0.543071451930669
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Tap2 ENSMUSG00000024339 0.0486700333825877 0.0730050500738816 0.0457858935505424 0.0730050500738816 0.292459239808644 0.292459239808644
Ncf2 ENSMUSG00000026480 0.0284778290913775 0.0854334872741324 0.11017430216519 0.165261453247786 0.184538003499826 0.184538003499826
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Snap23 ENSMUSG00000027287 0.082091502835136 0.246274508505408 0.457467168200083 0.686200752300124 0.962198703502844 0.962198703502844
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Tap1 ENSMUSG00000037321 0.324906399069635 0.487359598604452 0.81831478778474 0.81831478778474 0.235309833290101 0.487359598604452
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Ncf4 ENSMUSG00000071715 0.874452615520901 0.877580579097918 0.363018208530742 0.877580579097918 0.877580579097918 0.877580579097918
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379

Death Receptor Signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Gnb2l1 ENSMUSG00000020372 0.599362813972648 0.599362813972648 0.556064453494769 0.599362813972648 0.194011583926232 0.582034751778696
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Fgd2 ENSMUSG00000024013 0.161857626162729 0.242786439244094 0.322838555032344 0.322838555032344 0.107991630713536 0.242786439244094
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Ect2 ENSMUSG00000027699 0.77792794697507 0.890086585145094 0.890086585145094 0.890086585145094 0.833265230652966 0.890086585145094
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Arhgef19 ENSMUSG00000028919 0.607756072023105 0.911634108034657 0.0807069523274936 0.242120856982481 0.987400096134984 0.987400096134984
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Psenen ENSMUSG00000036835 0.203721213091886 0.30558181963783 0.062432064988998 0.187296194966994 0.391147422307809 0.391147422307809
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Arhgef10l ENSMUSG00000040964 0.196764129563487 0.350384610621833 0.233589740414555 0.350384610621833 0.585826905562777 0.585826905562777
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Fam105b ENSMUSG00000046034 0.0843703839428626 0.244470642610515 0.16298042840701 0.244470642610515 0.993696907141791 0.993696907141791
Adam17 ENSMUSG00000052593 0.18021850482087 0.54065551446261 0.424706107033476 0.610076476006283 0.610076476006283 0.610076476006283
Akap13 ENSMUSG00000066406 0.669623676240994 0.987398272706954 0.89324541901726 0.987398272706954 0.987398272706954 0.987398272706954
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Autodegradation of the E3 ubiquitin ligase COP1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

CDK-mediated phosphorylation and removal of Cdc6

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Stabilization of p53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rfwd2 ENSMUSG00000040782 0.800580801301414 0.890132851169815 0.054470226661549 0.163410679984647 0.890132851169815 0.890132851169815
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

DNA replication initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267

Interleukin-1 processing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Il1b ENSMUSG00000027398 0.72368117544925 0.974699219469781 0.974699219469781 0.974699219469781 0.544495972820067 0.974699219469781
Il1a ENSMUSG00000027399 0.164235756866076 0.492707270598228 0.686654083137288 0.686654083137288 0.362293981713938 0.543440972570907
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912

TRAF6 mediated NF-kB activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Ddx39 ENSMUSG00000005481 0.266365938779284 0.532596299455637 0.369580486206305 0.532596299455637 0.532596299455637 0.532596299455637
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Med8 ENSMUSG00000006392 0.256090699944685 0.373810541935696 0.0917016487295043 0.275104946188513 0.373810541935696 0.373810541935696
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pax5 ENSMUSG00000014030 0.0186093555017439 0.0558280665052318 0.204974322565396 0.307461483848093 0.657838226196952 0.657838226196952
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Suz12 ENSMUSG00000017548 0.862131725733286 0.930805877637186 0.91826375858401 0.930805877637186 0.930805877637186 0.930805877637186
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Sirt1 ENSMUSG00000020063 0.791414478789436 0.915141605502986 0.831202801623218 0.915141605502986 0.915141605502986 0.915141605502986
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Btg2 ENSMUSG00000020423 0.0554709543936204 0.166412863180861 0.26451387596011 0.292776156842983 0.292776156842983 0.292776156842983
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Zkscan17 ENSMUSG00000020472 0.104824971366656 0.314474914099968 0.289092354244328 0.433638531366492 0.981108384766924 0.981108384766924
Supt4a ENSMUSG00000020485 0.0625058326488859 0.187517497946658 0.489393978487283 0.489393978487283 0.388971088371462 0.489393978487283
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Nr1d1 ENSMUSG00000020889 0.037729783244716 0.113189349734148 0.209157490340506 0.209157490340506 0.0793152933452557 0.118972940017884
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Zfp839 ENSMUSG00000021271 0.282068891127281 0.436389799105874 0.29092653273725 0.436389799105874 0.865223184872352 0.865223184872352
Dek ENSMUSG00000021377 0.479308398166014 0.987399328842821 0.664102629729157 0.987399328842821 0.987399328842821 0.987399328842821
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Thrb ENSMUSG00000021779 0.908867691330257 0.908867691330257 0.707634351389092 0.908867691330257 0.785360984244778 0.908867691330257
Eaf1 ENSMUSG00000021890 0.88701835685625 0.88701835685625 0.132127787715956 0.396383363147867 0.752171520997964 0.88701835685625
Bnip3l ENSMUSG00000022051 0.157549939428809 0.236324909143213 0.110803282596096 0.236324909143213 0.273922096860272 0.273922096860272
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Atad2 ENSMUSG00000022360 0.352970992971963 0.798918026870966 0.840429237325643 0.840429237325643 0.532612017913977 0.798918026870966
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Zfp54 ENSMUSG00000023882 0.107398467562758 0.322195402688274 0.280311939376316 0.420467909064474 0.580367987289222 0.580367987289222
Zfp51 ENSMUSG00000023892 0.235190921747482 0.352786382621223 0.117196972981545 0.351590918944635 0.874462752666159 0.874462752666159
Cox7a2l ENSMUSG00000024248 0.843550103789667 0.843550103789667 0.713543280357916 0.843550103789667 0.604951121583963 0.843550103789667
Brd2 ENSMUSG00000024335 0.962223160725627 0.962223160725627 0.684299459384187 0.962223160725627 0.940221045852158 0.962223160725627
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Sirt3 ENSMUSG00000025486 0.136198946966682 0.225673657746083 0.150449105164055 0.225673657746083 0.371654935689413 0.371654935689413
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Smad7 ENSMUSG00000025880 0.649798395621747 0.896376264313015 0.761168517994278 0.896376264313015 0.896376264313015 0.896376264313015
Ing5 ENSMUSG00000026283 0.216953769437519 0.650861308312557 0.758176120614944 0.758176120614944 0.524849995102513 0.758176120614944
Esrrg ENSMUSG00000026610 0.672477722339562 0.698745137865805 0.658248858042778 0.698745137865805 0.698745137865805 0.698745137865805
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Ell3 ENSMUSG00000027246 0.92662721405129 0.92662721405129 0.596962483768408 0.895443725652613 0.575873236417166 0.895443725652613
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Tceb3 ENSMUSG00000028668 0.254372038202086 0.678506158806887 0.602190822724916 0.678506158806887 0.678506158806887 0.678506158806887
Tal1 ENSMUSG00000028717 0.803181825280339 0.803181825280339 0.324702995622202 0.803181825280339 0.687158429096566 0.803181825280339
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Triap1 ENSMUSG00000029535 0.0374929148817493 0.112478744645248 0.227409298159885 0.341113947239827 0.457622343285298 0.457622343285298
Zkscan14 ENSMUSG00000029627 0.877667464192645 0.984256935420092 0.880780791763657 0.984256935420092 0.984256935420092 0.984256935420092
Ezh2 ENSMUSG00000029687 0.782286313415417 0.87142225389964 0.393342680501779 0.87142225389964 0.87142225389964 0.87142225389964
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Eed ENSMUSG00000030619 0.0559764036544124 0.167929210963237 0.268006841635886 0.402010262453828 0.746093866961244 0.746093866961244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Sin3b ENSMUSG00000031622 0.952733639892361 0.952733639892361 0.511491664615441 0.952733639892361 0.731275407599301 0.952733639892361
Brd7 ENSMUSG00000031660 0.274643819833046 0.823931459499138 0.918252686805685 0.918252686805685 0.794427053313234 0.918252686805685
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Narg2 ENSMUSG00000032235 0.646948389636692 0.646948389636692 0.632831086366631 0.646948389636692 0.369536146110138 0.646948389636692
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Lmo2 ENSMUSG00000032698 0.433970192533923 0.433970192533923 0.169427628688144 0.27104776367791 0.180698509118606 0.27104776367791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Gtf2a2 ENSMUSG00000033543 0.591199025129356 0.621633440166777 0.621633440166777 0.621633440166777 0.426999601237835 0.621633440166777
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Vwa9 ENSMUSG00000034263 0.219698463359575 0.523033974968959 0.348689316645973 0.523033974968959 0.585594747924523 0.585594747924523
Med13 ENSMUSG00000034297 0.0701811382578752 0.210543414773626 0.357093837699953 0.53564075654993 0.977957839634294 0.977957839634294
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Gatad2a ENSMUSG00000036180 0.862120369682674 0.933946371176347 0.484424763284525 0.933946371176347 0.933946371176347 0.933946371176347
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Elf1 ENSMUSG00000036461 0.740193790947836 0.740193790947836 0.740174990210497 0.740193790947836 0.599460938221545 0.740193790947836
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Zfp113 ENSMUSG00000037007 0.48198061459868 0.722970921898021 0.764154844671624 0.764154844671624 0.174287827316986 0.522863481950959
Elf2 ENSMUSG00000037174 0.843511612134173 0.843511612134173 0.402086839746097 0.843511612134173 0.627112152298218 0.843511612134173
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Smarce1 ENSMUSG00000037935 0.773237987055144 0.952793633147213 0.952793633147213 0.952793633147213 0.722394347727836 0.952793633147213
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Foxp3 ENSMUSG00000039521 0.82048901146847 0.989694584991145 0.86553259272103 0.989694584991145 0.989694584991145 0.989694584991145
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Thoc6 ENSMUSG00000041319 0.658299158938436 0.725211259395702 0.725211259395702 0.725211259395702 0.316993797124339 0.725211259395702
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cox19 ENSMUSG00000045438 0.630020093033922 0.66409928319106 0.66409928319106 0.66409928319106 0.344805790981147 0.66409928319106
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Zfp710 ENSMUSG00000048897 0.564184858845317 0.846277288267975 0.486900237975711 0.846277288267975 1 1
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Maml1 ENSMUSG00000050567 0.849727679593125 0.849727679593125 0.818911566463586 0.849727679593125 0.834281670694547 0.849727679593125
Zfp455 ENSMUSG00000051037 0.764022731411663 0.85893458048499 0.474566507719613 0.85893458048499 0.85893458048499 0.85893458048499
Zfp52 ENSMUSG00000051341 0.78829254223511 0.78829254223511 0.440981173924791 0.78829254223511 0.687060498605718 0.78829254223511
Prdm9 ENSMUSG00000051977 0.905727726614082 0.905727726614082 0.524861443088293 0.78729216463244 0.166927746811478 0.500783240434435
Zfp472 ENSMUSG00000053600 0.287402210782007 0.86220663234602 0.88697555467567 0.88697555467567 0.755089264429628 0.88697555467567
AI987944 ENSMUSG00000056383 0.046943389408073 0.083212566418127 0.0554750442787513 0.083212566418127 0.408216767392623 0.408216767392623
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Zfp53 ENSMUSG00000057409 0.596604814915064 0.855859911520181 0.855859911520181 0.855859911520181 0.791279357193469 0.855859911520181
Zfp595 ENSMUSG00000057842 0.122808665645878 0.368425996937634 0.484265413652523 0.726398120478784 0.727900911027923 0.727900911027923
Rsl1 ENSMUSG00000058900 0.0584419490614589 0.175325847184377 0.849689489598832 0.849689489598832 0.54276353235559 0.814145298533385
Zfp945 ENSMUSG00000059142 0.340478721846338 0.378165145753242 0.176602125959318 0.378165145753242 0.378165145753242 0.378165145753242
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Nr1h2 ENSMUSG00000060601 0.56147429589878 0.56147429589878 0.415654486437077 0.56147429589878 0.530007595823729 0.56147429589878
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Tgif2 ENSMUSG00000062175 0.0239283787827764 0.0717851363483292 0.716395803810444 0.758140057113732 0.758140057113732 0.758140057113732
Zfp677 ENSMUSG00000062743 0.50693304889277 0.50693304889277 0.365429855786619 0.50693304889277 0.354988555585396 0.50693304889277
Hdac10 ENSMUSG00000062906 0.0438411444736475 0.131523433420942 0.315215322517597 0.315215322517597 0.187244659337631 0.280866989006447
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Zfp69 ENSMUSG00000064141 0.800392829713434 0.974789757595072 0.974789757595072 0.974789757595072 0.758158038538366 0.974789757595072
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
Mta2 ENSMUSG00000071646 0.871439535891264 0.871439535891264 0.80053481253197 0.871439535891264 0.710463049196743 0.871439535891264
4930522L14Rik ENSMUSG00000072762 0.704436857185727 0.877542736319083 0.698593453067751 0.877542736319083 0.877542736319083 0.877542736319083
5430403G16Rik ENSMUSG00000072763 0.737150506589246 0.971657617996358 0.346767950477885 0.971657617996358 0.971657617996358 0.971657617996358
Gm21994 ENSMUSG00000074735 0.43771368652445 0.43771368652445 0.230077923702433 0.43771368652445 0.403517247683641 0.43771368652445
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Sarnp ENSMUSG00000078427 0.129072399107977 0.273145551583203 0.182097034388802 0.273145551583203 0.918249374405348 0.918249374405348
Gm13212 ENSMUSG00000078502 0.459121900778597 0.614422682067283 0.0193616841614488 0.0580850524843463 0.614422682067283 0.614422682067283
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Smarcd2 ENSMUSG00000078619 0.725323748108241 0.773235770097311 0.773235770097311 0.773235770097311 0.496882397396578 0.773235770097311
Zfp429 ENSMUSG00000078994 0.189623757130002 0.568871271390006 0.596748154975984 0.596748154975984 0.476549702044465 0.596748154975984
Zfp456 ENSMUSG00000078995 0.13010991999385 0.39032975998155 0.499411678679109 0.718043510024566 0.718043510024566 0.718043510024566
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Med12 ENSMUSG00000079487 0.527431304067025 0.527431304067025 0.457666072739171 0.527431304067025 0.438728761719674 0.527431304067025
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Zfp97 ENSMUSG00000095990 0.266401009134915 0.399601513702372 0.254521957181761 0.399601513702372 0.479504814652902 0.479504814652902
Zfp433 ENSMUSG00000096795 0.249587181016902 0.444687616335941 0.296458410890627 0.444687616335941 0.710577880375194 0.710577880375194

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cyclin A:Cdk2-associated events at S phase entry

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

NIK–>noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Relb ENSMUSG00000002983 0.615941705286754 0.843536718609304 0.231967452861212 0.695902358583636 0.843536718609304 0.843536718609304
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Translesion synthesis by POLI

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p75NTR signals via NF-kB

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

SUMO E3 ligases SUMOylate target proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Suz12 ENSMUSG00000017548 0.862131725733286 0.930805877637186 0.91826375858401 0.930805877637186 0.930805877637186 0.930805877637186
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Smc6 ENSMUSG00000020608 0.287431607894417 0.86229482368325 0.675615959368741 0.896374596040243 0.896374596040243 0.896374596040243
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Top2a ENSMUSG00000020914 0.0508286730390646 0.152486019117194 0.615481542799229 0.615481542799229 0.590633647308629 0.615481542799229
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Trim27 ENSMUSG00000021326 0.289152170558842 0.433728255838263 0.0257185326540514 0.0771555979621541 0.752151921919646 0.752151921919646
Thrb ENSMUSG00000021779 0.908867691330257 0.908867691330257 0.707634351389092 0.908867691330257 0.785360984244778 0.908867691330257
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Sp100 ENSMUSG00000026222 0.684228399751986 0.746182300580058 0.746182300580058 0.746182300580058 0.506940699407348 0.746182300580058
Sp3 ENSMUSG00000027109 0.301997742200367 0.45299661330055 0.289249328870587 0.45299661330055 0.743150252273982 0.743150252273982
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Dnmt3b ENSMUSG00000027478 0.264153521975037 0.396230282962556 0.740148992591262 0.740148992591262 0.0330573727406786 0.0991721182220359
Casp8ap2 ENSMUSG00000028282 0.0559986895417638 0.100579928698245 0.0670532857988303 0.100579928698245 0.749017407685416 0.749017407685416
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Topors ENSMUSG00000036822 0.66688807896104 0.740128586413599 0.681351313094283 0.740128586413599 0.740128586413599 0.740128586413599
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Nsmce4a ENSMUSG00000040331 0.770162982305828 0.770162982305828 0.450431120945099 0.675646681417648 0.41563715805767 0.675646681417648
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Nr1h2 ENSMUSG00000060601 0.56147429589878 0.56147429589878 0.415654486437077 0.56147429589878 0.530007595823729 0.56147429589878
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246

Translesion synthesis by REV1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

SUMOylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Brca1 ENSMUSG00000017146 0.748427074281598 0.748427074281598 0.686213613723239 0.748427074281598 0.610722767152333 0.748427074281598
Suz12 ENSMUSG00000017548 0.862131725733286 0.930805877637186 0.91826375858401 0.930805877637186 0.930805877637186 0.930805877637186
Birc5 ENSMUSG00000017716 0.962076059107069 0.962076059107069 0.479389322374719 0.719083983562078 0.224261109398884 0.672783328196652
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Smc6 ENSMUSG00000020608 0.287431607894417 0.86229482368325 0.675615959368741 0.896374596040243 0.896374596040243 0.896374596040243
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Top2a ENSMUSG00000020914 0.0508286730390646 0.152486019117194 0.615481542799229 0.615481542799229 0.590633647308629 0.615481542799229
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Trim27 ENSMUSG00000021326 0.289152170558842 0.433728255838263 0.0257185326540514 0.0771555979621541 0.752151921919646 0.752151921919646
Thrb ENSMUSG00000021779 0.908867691330257 0.908867691330257 0.707634351389092 0.908867691330257 0.785360984244778 0.908867691330257
Incenp ENSMUSG00000024660 0.871377293786058 0.871377293786058 0.484265364734869 0.871377293786058 0.734229406997922 0.871377293786058
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Nop58 ENSMUSG00000026020 0.0887498965646427 0.266249689693928 0.684277802788144 0.911992686870108 0.911992686870108 0.911992686870108
Sp100 ENSMUSG00000026222 0.684228399751986 0.746182300580058 0.746182300580058 0.746182300580058 0.506940699407348 0.746182300580058
Sp3 ENSMUSG00000027109 0.301997742200367 0.45299661330055 0.289249328870587 0.45299661330055 0.743150252273982 0.743150252273982
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Dnmt3b ENSMUSG00000027478 0.264153521975037 0.396230282962556 0.740148992591262 0.740148992591262 0.0330573727406786 0.0991721182220359
Casp8ap2 ENSMUSG00000028282 0.0559986895417638 0.100579928698245 0.0670532857988303 0.100579928698245 0.749017407685416 0.749017407685416
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Cdca8 ENSMUSG00000028873 0.719954882163912 0.961913244517889 0.0776989783318799 0.23309693499564 0.961913244517889 0.961913244517889
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Senp1 ENSMUSG00000033075 0.713523062288705 0.865240788587913 0.865240788587913 0.865240788587913 0.779289796981815 0.865240788587913
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Topors ENSMUSG00000036822 0.66688807896104 0.740128586413599 0.681351313094283 0.740128586413599 0.740128586413599 0.740128586413599
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Nsmce4a ENSMUSG00000040331 0.770162982305828 0.770162982305828 0.450431120945099 0.675646681417648 0.41563715805767 0.675646681417648
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Nr1h2 ENSMUSG00000060601 0.56147429589878 0.56147429589878 0.415654486437077 0.56147429589878 0.530007595823729 0.56147429589878
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Mefv ENSMUSG00000022534 0.840840226570052 0.840840226570052 0.747234696137759 0.840840226570052 0.266684635738278 0.800053907214833
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Pycard ENSMUSG00000030793 0.984246169095958 0.984246169095958 0.491594861375365 0.817656738089717 0.545104492059812 0.817656738089717
Nlrp3 ENSMUSG00000032691 0.959066190619886 0.959066190619886 0.632626229686031 0.948939344529047 0.203628050784067 0.6108841523522
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Aim2 ENSMUSG00000037860 0.731086205696361 0.871350032640993 0.455273305926355 0.871350032640993 0.871350032640993 0.871350032640993
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Nlrp1a ENSMUSG00000069830 0.522940617415826 0.784410926123738 0.893200773561383 0.893200773561383 0.35492385366701 0.784410926123738
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of RUNX3 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

CDT1 association with the CDC6:ORC:origin complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdt1 ENSMUSG00000006585 0.266211629913532 0.711040897545429 0.474027265030286 0.711040897545429 0.88014082222942 0.88014082222942
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdc6 ENSMUSG00000017499 0.351056252123617 0.918145836809493 0.805618215531469 0.918145836809493 0.918145836809493 0.918145836809493
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Orc1 ENSMUSG00000028587 0.166301412303445 0.347670468950814 0.231780312633876 0.347670468950814 0.524629545321174 0.524629545321174
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Sp1 ENSMUSG00000001280 0.930807434466582 0.930807434466582 0.334776743283851 0.523226130942651 0.348817420628434 0.523226130942651
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Top3a ENSMUSG00000002814 0.0529725831565553 0.158917749469666 0.431666811925636 0.627209373113078 0.627209373113078 0.627209373113078
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Stk11 ENSMUSG00000003068 0.322509604837491 0.483764407256237 0.10742770790407 0.322283123712209 0.73398788133423 0.73398788133423
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Med8 ENSMUSG00000006392 0.256090699944685 0.373810541935696 0.0917016487295043 0.275104946188513 0.373810541935696 0.373810541935696
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pax5 ENSMUSG00000014030 0.0186093555017439 0.0558280665052318 0.204974322565396 0.307461483848093 0.657838226196952 0.657838226196952
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Suz12 ENSMUSG00000017548 0.862131725733286 0.930805877637186 0.91826375858401 0.930805877637186 0.930805877637186 0.930805877637186
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Sirt1 ENSMUSG00000020063 0.791414478789436 0.915141605502986 0.831202801623218 0.915141605502986 0.915141605502986 0.915141605502986
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Btg2 ENSMUSG00000020423 0.0554709543936204 0.166412863180861 0.26451387596011 0.292776156842983 0.292776156842983 0.292776156842983
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Zkscan17 ENSMUSG00000020472 0.104824971366656 0.314474914099968 0.289092354244328 0.433638531366492 0.981108384766924 0.981108384766924
Supt4a ENSMUSG00000020485 0.0625058326488859 0.187517497946658 0.489393978487283 0.489393978487283 0.388971088371462 0.489393978487283
Taf15 ENSMUSG00000020680 0.566815535378277 0.850223303067416 0.357101322176205 0.850223303067416 0.974808356439872 0.974808356439872
Nr1d1 ENSMUSG00000020889 0.037729783244716 0.113189349734148 0.209157490340506 0.209157490340506 0.0793152933452557 0.118972940017884
Aurkb ENSMUSG00000020897 0.731188332802893 0.965303081589268 0.965303081589268 0.965303081589268 0.745831988585838 0.965303081589268
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Zfp839 ENSMUSG00000021271 0.282068891127281 0.436389799105874 0.29092653273725 0.436389799105874 0.865223184872352 0.865223184872352
Dek ENSMUSG00000021377 0.479308398166014 0.987399328842821 0.664102629729157 0.987399328842821 0.987399328842821 0.987399328842821
Rad17 ENSMUSG00000021635 0.0034417448432528 0.0103252345297584 0.223935851721001 0.335903777581501 0.943299341716077 0.943299341716077
Thrb ENSMUSG00000021779 0.908867691330257 0.908867691330257 0.707634351389092 0.908867691330257 0.785360984244778 0.908867691330257
Bnip3l ENSMUSG00000022051 0.157549939428809 0.236324909143213 0.110803282596096 0.236324909143213 0.273922096860272 0.273922096860272
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Myc ENSMUSG00000022346 0.222392518715408 0.667177556146223 0.734025227335301 0.825018986646939 0.825018986646939 0.825018986646939
Atad2 ENSMUSG00000022360 0.352970992971963 0.798918026870966 0.840429237325643 0.840429237325643 0.532612017913977 0.798918026870966
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Zfp54 ENSMUSG00000023882 0.107398467562758 0.322195402688274 0.280311939376316 0.420467909064474 0.580367987289222 0.580367987289222
Zfp51 ENSMUSG00000023892 0.235190921747482 0.352786382621223 0.117196972981545 0.351590918944635 0.874462752666159 0.874462752666159
Cox7a2l ENSMUSG00000024248 0.843550103789667 0.843550103789667 0.713543280357916 0.843550103789667 0.604951121583963 0.843550103789667
Brd2 ENSMUSG00000024335 0.962223160725627 0.962223160725627 0.684299459384187 0.962223160725627 0.940221045852158 0.962223160725627
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Rad9a ENSMUSG00000024824 0.198298186006576 0.594894558019727 0.467297299768014 0.630025868019963 0.630025868019963 0.630025868019963
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Sirt3 ENSMUSG00000025486 0.136198946966682 0.225673657746083 0.150449105164055 0.225673657746083 0.371654935689413 0.371654935689413
Lrdd ENSMUSG00000025507 0.540063244625938 0.902549224386223 0.690100713464552 0.902549224386223 0.902549224386223 0.902549224386223
Smad7 ENSMUSG00000025880 0.649798395621747 0.896376264313015 0.761168517994278 0.896376264313015 0.896376264313015 0.896376264313015
Ing5 ENSMUSG00000026283 0.216953769437519 0.650861308312557 0.758176120614944 0.758176120614944 0.524849995102513 0.758176120614944
Esrrg ENSMUSG00000026610 0.672477722339562 0.698745137865805 0.658248858042778 0.698745137865805 0.698745137865805 0.698745137865805
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Trp53inp1 ENSMUSG00000028211 0.0195052109492501 0.0585156328477502 0.527397453217642 0.72530024825932 0.72530024825932 0.72530024825932
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Prkaa2 ENSMUSG00000028518 0.404238112917482 0.654494729051476 0.436329819367651 0.654494729051476 0.89009682408259 0.89009682408259
Tceb3 ENSMUSG00000028668 0.254372038202086 0.678506158806887 0.602190822724916 0.678506158806887 0.678506158806887 0.678506158806887
Tal1 ENSMUSG00000028717 0.803181825280339 0.803181825280339 0.324702995622202 0.803181825280339 0.687158429096566 0.803181825280339
Hdac1 ENSMUSG00000028800 0.962221335247873 0.962221335247873 0.641263484708483 0.961895227062725 0.613288718513174 0.961895227062725
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Taf12 ENSMUSG00000028899 0.113720526092744 0.341161578278231 0.993702144556933 0.993702144556933 0.591240495855691 0.886860743783537
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Prkab1 ENSMUSG00000029513 0.36751515637847 0.959083175339142 0.959083175339142 0.959083175339142 0.78839771868289 0.959083175339142
Chek2 ENSMUSG00000029521 0.731121389908262 0.731121389908262 0.212415929066677 0.516610332769469 0.34440688851298 0.516610332769469
Triap1 ENSMUSG00000029535 0.0374929148817493 0.112478744645248 0.227409298159885 0.341113947239827 0.457622343285298 0.457622343285298
Zkscan14 ENSMUSG00000029627 0.877667464192645 0.984256935420092 0.880780791763657 0.984256935420092 0.984256935420092 0.984256935420092
Ezh2 ENSMUSG00000029687 0.782286313415417 0.87142225389964 0.393342680501779 0.87142225389964 0.87142225389964 0.87142225389964
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Eed ENSMUSG00000030619 0.0559764036544124 0.167929210963237 0.268006841635886 0.402010262453828 0.746093866961244 0.746093866961244
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Sin3b ENSMUSG00000031622 0.952733639892361 0.952733639892361 0.511491664615441 0.952733639892361 0.731275407599301 0.952733639892361
Brd7 ENSMUSG00000031660 0.274643819833046 0.823931459499138 0.918252686805685 0.918252686805685 0.794427053313234 0.918252686805685
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Rora ENSMUSG00000032238 0.652658766065095 0.652658766065095 0.408902978188971 0.652658766065095 0.574954553599087 0.652658766065095
Topbp1 ENSMUSG00000032555 0.915142492697731 0.915142492697731 0.27154491207657 0.814634736229709 0.641312231675819 0.915142492697731
Lmo2 ENSMUSG00000032698 0.433970192533923 0.433970192533923 0.169427628688144 0.27104776367791 0.180698509118606 0.27104776367791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Med13 ENSMUSG00000034297 0.0701811382578752 0.210543414773626 0.357093837699953 0.53564075654993 0.977957839634294 0.977957839634294
Brip1 ENSMUSG00000034329 0.219477561404694 0.399736958087307 0.399736958087307 0.399736958087307 0.316675250838161 0.399736958087307
Cnot6l ENSMUSG00000034724 0.390978135241901 0.586467202862852 0.893159612219939 0.893159612219939 0.344504082248012 0.586467202862852
Rmi1 ENSMUSG00000035367 0.599448003320196 0.921405396879863 0.921405396879863 0.921405396879863 0.734247145759676 0.921405396879863
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Gatad2a ENSMUSG00000036180 0.862120369682674 0.933946371176347 0.484424763284525 0.933946371176347 0.933946371176347 0.933946371176347
Gadd45a ENSMUSG00000036390 0.896371466373282 0.896371466373282 0.145943627141802 0.437830881425406 0.782315896664831 0.896371466373282
Elf1 ENSMUSG00000036461 0.740193790947836 0.740193790947836 0.740174990210497 0.740193790947836 0.599460938221545 0.740193790947836
Cnot1 ENSMUSG00000036550 0.340749965442398 0.547978691365846 0.993700358446219 0.993700358446219 0.365319127577231 0.547978691365846
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Pml ENSMUSG00000036986 0.818901886290872 0.987404632260337 0.987404632260337 0.987404632260337 0.621563879031599 0.987404632260337
Zfp113 ENSMUSG00000037007 0.48198061459868 0.722970921898021 0.764154844671624 0.764154844671624 0.174287827316986 0.522863481950959
Elf2 ENSMUSG00000037174 0.843511612134173 0.843511612134173 0.402086839746097 0.843511612134173 0.627112152298218 0.843511612134173
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Smarce1 ENSMUSG00000037935 0.773237987055144 0.952793633147213 0.952793633147213 0.952793633147213 0.722394347727836 0.952793633147213
Rmi2 ENSMUSG00000037991 0.489623621397622 0.638591388734574 0.374959709154773 0.638591388734574 0.638591388734574 0.638591388734574
Rara ENSMUSG00000037992 0.596712877818654 0.911992040725591 0.911992040725591 0.911992040725591 0.821975695608022 0.911992040725591
Foxp3 ENSMUSG00000039521 0.82048901146847 0.989694584991145 0.86553259272103 0.989694584991145 0.989694584991145 0.989694584991145
Exo1 ENSMUSG00000039748 0.728365181644255 0.839429614783038 0.839429614783038 0.839429614783038 0.711892052765503 0.839429614783038
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Sin3a ENSMUSG00000042557 0.779284778579786 0.825036449930719 0.731228822996603 0.825036449930719 0.825036449930719 0.825036449930719
Taf10 ENSMUSG00000043866 0.0235886282911753 0.0353829424367629 0.00489339615228622 0.0146801884568587 0.607567065003592 0.607567065003592
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456
Cox19 ENSMUSG00000045438 0.630020093033922 0.66409928319106 0.66409928319106 0.66409928319106 0.344805790981147 0.66409928319106
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Zfp710 ENSMUSG00000048897 0.564184858845317 0.846277288267975 0.486900237975711 0.846277288267975 1 1
4930486L24Rik ENSMUSG00000050345 0.550845607438368 0.550845607438368 0.159696791439886 0.479090374319658 0.550837051293843 0.550845607438368
Maml1 ENSMUSG00000050567 0.849727679593125 0.849727679593125 0.818911566463586 0.849727679593125 0.834281670694547 0.849727679593125
Zfp455 ENSMUSG00000051037 0.764022731411663 0.85893458048499 0.474566507719613 0.85893458048499 0.85893458048499 0.85893458048499
Zfp52 ENSMUSG00000051341 0.78829254223511 0.78829254223511 0.440981173924791 0.78829254223511 0.687060498605718 0.78829254223511
Prdm9 ENSMUSG00000051977 0.905727726614082 0.905727726614082 0.524861443088293 0.78729216463244 0.166927746811478 0.500783240434435
Zfp472 ENSMUSG00000053600 0.287402210782007 0.86220663234602 0.88697555467567 0.88697555467567 0.755089264429628 0.88697555467567
AI987944 ENSMUSG00000056383 0.046943389408073 0.083212566418127 0.0554750442787513 0.083212566418127 0.408216767392623 0.408216767392623
Npm1 ENSMUSG00000057113 0.0910374069884158 0.199578715379424 0.133052476919616 0.199578715379424 0.974802064756267 0.974802064756267
Zfp53 ENSMUSG00000057409 0.596604814915064 0.855859911520181 0.855859911520181 0.855859911520181 0.791279357193469 0.855859911520181
Zfp595 ENSMUSG00000057842 0.122808665645878 0.368425996937634 0.484265413652523 0.726398120478784 0.727900911027923 0.727900911027923
Rsl1 ENSMUSG00000058900 0.0584419490614589 0.175325847184377 0.849689489598832 0.849689489598832 0.54276353235559 0.814145298533385
Zfp945 ENSMUSG00000059142 0.340478721846338 0.378165145753242 0.176602125959318 0.378165145753242 0.378165145753242 0.378165145753242
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Nr1h2 ENSMUSG00000060601 0.56147429589878 0.56147429589878 0.415654486437077 0.56147429589878 0.530007595823729 0.56147429589878
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
H3f3a ENSMUSG00000060743 0.307669201681039 0.461503802521559 0.806688909116374 0.806688909116374 0.0910600228211059 0.273180068463318
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Tgif2 ENSMUSG00000062175 0.0239283787827764 0.0717851363483292 0.716395803810444 0.758140057113732 0.758140057113732 0.758140057113732
Zfp677 ENSMUSG00000062743 0.50693304889277 0.50693304889277 0.365429855786619 0.50693304889277 0.354988555585396 0.50693304889277
Hdac10 ENSMUSG00000062906 0.0438411444736475 0.131523433420942 0.315215322517597 0.315215322517597 0.187244659337631 0.280866989006447
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Zfp69 ENSMUSG00000064141 0.800392829713434 0.974789757595072 0.974789757595072 0.974789757595072 0.758158038538366 0.974789757595072
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
Mta2 ENSMUSG00000071646 0.871439535891264 0.871439535891264 0.80053481253197 0.871439535891264 0.710463049196743 0.871439535891264
4930522L14Rik ENSMUSG00000072762 0.704436857185727 0.877542736319083 0.698593453067751 0.877542736319083 0.877542736319083 0.877542736319083
5430403G16Rik ENSMUSG00000072763 0.737150506589246 0.971657617996358 0.346767950477885 0.971657617996358 0.971657617996358 0.971657617996358
Gm21994 ENSMUSG00000074735 0.43771368652445 0.43771368652445 0.230077923702433 0.43771368652445 0.403517247683641 0.43771368652445
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Gm13212 ENSMUSG00000078502 0.459121900778597 0.614422682067283 0.0193616841614488 0.0580850524843463 0.614422682067283 0.614422682067283
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Smarcd2 ENSMUSG00000078619 0.725323748108241 0.773235770097311 0.773235770097311 0.773235770097311 0.496882397396578 0.773235770097311
Zfp429 ENSMUSG00000078994 0.189623757130002 0.568871271390006 0.596748154975984 0.596748154975984 0.476549702044465 0.596748154975984
Zfp456 ENSMUSG00000078995 0.13010991999385 0.39032975998155 0.499411678679109 0.718043510024566 0.718043510024566 0.718043510024566
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Med12 ENSMUSG00000079487 0.527431304067025 0.527431304067025 0.457666072739171 0.527431304067025 0.438728761719674 0.527431304067025
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126
Zfp97 ENSMUSG00000095990 0.266401009134915 0.399601513702372 0.254521957181761 0.399601513702372 0.479504814652902 0.479504814652902
Zfp433 ENSMUSG00000096795 0.249587181016902 0.444687616335941 0.296458410890627 0.444687616335941 0.710577880375194 0.710577880375194

The role of GTSE1 in G2/M progression after G2 checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Tubb1 ENSMUSG00000016255 0.487348004425386 0.731022006638079 0.298270867289781 0.731022006638079 0.790016241814838 0.790016241814838
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Gtse1 ENSMUSG00000022385 0.852054925796974 0.852054925796974 0.524435229079944 0.852054925796974 0.767374504415769 0.852054925796974
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Zfp830 ENSMUSG00000046010 0.574968999682525 0.831211863248003 0.481959295162291 0.831211863248003 0.831211863248003 0.831211863248003
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Ubiquitin-dependent degradation of Cyclin D

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Translesion synthesis by POLK

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

MAPK6/MAPK4 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Cdc14a ENSMUSG00000033502 0.962227126960181 0.962227126960181 0.902623796656451 0.962227126960181 0.871455971516871 0.962227126960181
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Cdc42ep3 ENSMUSG00000036533 0.37164159571415 0.557462393571225 0.0872163823566719 0.261649147070016 0.977958307206886 0.977958307206886
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Foxo1 ENSMUSG00000044167 0.968491890322711 0.968491890322711 0.365385023487155 0.968491890322711 0.806548901708692 0.968491890322711
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of PLK1 Activity at G2/M Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Bora ENSMUSG00000022070 0.440766423606727 0.830081346867545 0.84043263187544 0.84043263187544 0.553387564578363 0.830081346867545
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Platelet activation, signaling and aggregation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Srgn ENSMUSG00000020077 0.88698664227401 0.88698664227401 0.871426140819813 0.88698664227401 0.627143733315847 0.88698664227401
Plek ENSMUSG00000020120 0.373785174363082 0.698852736258662 0.698852736258662 0.698852736258662 0.698785136556877 0.698852736258662
Pik3cg ENSMUSG00000020573 0.959010989538482 0.968468985376622 0.968468985376622 0.968468985376622 0.357018709825827 0.968468985376622
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Itgb3 ENSMUSG00000020689 0.843349345537671 0.843349345537671 0.328821512152547 0.49323226822882 0.3089713347122 0.49323226822882
Pik3r5 ENSMUSG00000020901 0.758135135734028 0.758135135734028 0.154844462596217 0.25384816306267 0.169232108708446 0.25384816306267
Prkch ENSMUSG00000021108 0.63003435790702 0.63003435790702 0.318899275310062 0.63003435790702 0.61025994138694 0.63003435790702
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
F2rl2 ENSMUSG00000021675 0.629261306737558 0.71186645052147 0.71186645052147 0.71186645052147 0.593649850933869 0.71186645052147
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Gtpbp2 ENSMUSG00000023952 0.874530989128772 0.874530989128772 0.33877396662764 0.704532771821832 0.469688514547888 0.704532771821832
Ctsw ENSMUSG00000024910 0.692217950370342 0.692217950370342 0.442083512180914 0.692217950370342 0.546494256518131 0.692217950370342
Fermt3 ENSMUSG00000024965 0.464768747400279 0.464768747400279 0.108799156668991 0.326397470006974 0.399385485371262 0.464768747400279
Nhlrc2 ENSMUSG00000025078 0.0901555164936531 0.270466549480959 0.675554569359775 0.675554569359775 0.484441037189827 0.675554569359775
Dgka ENSMUSG00000025357 0.893199468336594 0.893199468336594 0.553566080948085 0.830349121422128 0.452544002116966 0.830349121422128
Tagln2 ENSMUSG00000026547 0.605001195865311 0.728301141096722 0.239997600253922 0.719992800761767 0.728301141096722 0.728301141096722
Selp ENSMUSG00000026580 0.84619470438273 0.84619470438273 0.28502415479393 0.620769985649495 0.413846657099664 0.620769985649495
Apbb1ip ENSMUSG00000026786 0.984222718319748 0.984222718319748 0.936980388171146 0.984222718319748 0.582832358879193 0.984222718319748
Anxa5 ENSMUSG00000027712 0.993702334404518 0.993702334404518 0.710600416604755 0.993702334404518 0.30395148577911 0.911854457337331
Stxbp3a ENSMUSG00000027882 0.397766509181114 0.596649763771671 0.0760391721602443 0.228117516480733 0.794482895155827 0.794482895155827
Tln1 ENSMUSG00000028465 0.572130411303441 0.65267344990602 0.0915572537081786 0.274671761124536 0.65267344990602 0.65267344990602
Ppbp ENSMUSG00000029372 0.757876892323099 0.993619366606269 0.127779501653182 0.383338504959547 0.993619366606269 0.993619366606269
Pf4 ENSMUSG00000029373 0.899343448384416 0.899343448384416 0.680807735581805 0.899343448384416 0.558898010233686 0.899343448384416
Gp9 ENSMUSG00000030054 0.00377310954923169 0.0113193286476951 0.619292967855541 0.635911427193935 0.635911427193935 0.635911427193935
Clec1b ENSMUSG00000030159 0.109815078009729 0.329445234029186 0.905662764674105 0.905662764674105 0.452311992223792 0.678467988335688
Cd9 ENSMUSG00000030342 0.782287048401791 0.782287048401791 0.672602879829628 0.782287048401791 0.274831162294734 0.782287048401791
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Flna ENSMUSG00000031328 0.812768584424391 0.812768584424391 0.615990120361259 0.812768584424391 0.564120147031627 0.812768584424391
Vegfc ENSMUSG00000031520 0.0190679710695843 0.057203913208753 0.146941623747318 0.220412435620977 0.946508644048411 0.946508644048411
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Rasgrp2 ENSMUSG00000032946 0.949647317174592 0.949647317174592 0.627230501385055 0.949647317174592 0.815858716416287 0.949647317174592
Rac2 ENSMUSG00000033220 0.35280659956241 0.35280659956241 0.0546842747988449 0.164052824396535 0.111658288883034 0.167487433324551
Lgals3bp ENSMUSG00000033880 0.785324919317497 0.785324919317497 0.246194956391243 0.697189026542338 0.464792684361559 0.697189026542338
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
Itga2b ENSMUSG00000034664 0.454979940495822 0.548216013468298 0.548216013468298 0.548216013468298 0.491801608886593 0.548216013468298
Gna15 ENSMUSG00000034792 0.461976700843078 0.461976700843078 0.203672627663993 0.30550894149599 0.0462529880702313 0.138758964210694
Tbxa2r ENSMUSG00000034881 0.169135942438759 0.253703913658139 0.0934023198373406 0.253703913658139 0.787960310844493 0.787960310844493
Ly6g6f ENSMUSG00000034923 0.554455085640324 0.787686218888171 0.15606107088074 0.468183212642219 0.787686218888171 0.787686218888171
Gngt2 ENSMUSG00000038811 0.120071094167931 0.246769414637224 0.164512943091482 0.246769414637224 0.413204658662696 0.413204658662696
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Itpr3 ENSMUSG00000042644 0.385040302372643 0.812853192549265 0.889966090429597 0.889966090429597 0.541902128366176 0.812853192549265
Pik3r6 ENSMUSG00000046207 0.672725690076328 0.672725690076328 0.103143832603183 0.29950223065588 0.199668153770587 0.29950223065588
Tmsb4x ENSMUSG00000049775 0.905754549410294 0.905754549410294 0.770227624847008 0.905754549410294 0.627240621674158 0.905754549410294
F2rl3 ENSMUSG00000050147 0.566362337529305 0.641022029317539 0.159455585790563 0.478366757371688 0.641022029317539 0.641022029317539
Rap1b ENSMUSG00000052681 0.484435808203048 0.855918470668146 0.855918470668146 0.855918470668146 0.849739933372866 0.855918470668146
Pla2g4a ENSMUSG00000056220 0.318749008972887 0.616134501396929 0.41075633426462 0.616134501396929 0.649592772559609 0.649592772559609
Fcer1g ENSMUSG00000058715 0.0413224082995369 0.123967224898611 0.264567697658663 0.396851546487995 0.825051639504641 0.825051639504641
Tor4a ENSMUSG00000059555 0.886996924233646 0.886996924233646 0.384462142478169 0.626856703424757 0.417904468949838 0.626856703424757
Brpf3 ENSMUSG00000063952 0.743032645171901 0.880585564344473 0.719165348168217 0.880585564344473 0.880585564344473 0.880585564344473
Rap1a ENSMUSG00000068798 0.182050070203919 0.546150210611757 0.843521863247626 0.843521863247626 0.664069758876297 0.843521863247626
AU023871 ENSMUSG00000073414 0.244052682708912 0.721710295011787 0.640487037391299 0.721710295011787 0.721710295011787 0.721710295011787
Rhog ENSMUSG00000073982 0.78532863891503 0.78532863891503 0.101402194109372 0.304206582328117 0.229038762681918 0.343558144022877

Transcriptional regulation by RUNX3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Brd2 ENSMUSG00000024335 0.962223160725627 0.962223160725627 0.684299459384187 0.962223160725627 0.940221045852158 0.962223160725627
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Maml1 ENSMUSG00000050567 0.849727679593125 0.849727679593125 0.818911566463586 0.849727679593125 0.834281670694547 0.849727679593125
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Runx3 ENSMUSG00000070691 0.294225899438012 0.882677698314037 0.639968490133529 0.893414938483749 0.893414938483749 0.893414938483749
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll Like Receptor 3 (TLR3) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0166694610077386 0.0500083830232158 0.924437275664023 0.924437275664023 0.593783146350941 0.890674719526412
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Hnrnpa2b1 ENSMUSG00000004980 0.69886671783146 0.725341707588167 0.725341707588167 0.725341707588167 0.644149912834405 0.725341707588167
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Ddx39 ENSMUSG00000005481 0.266365938779284 0.532596299455637 0.369580486206305 0.532596299455637 0.532596299455637 0.532596299455637
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Snrpb2 ENSMUSG00000008333 0.111876468464953 0.316247284683075 0.21083152312205 0.316247284683075 0.943361205125621 0.943361205125621
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Ccar1 ENSMUSG00000020074 0.0895399812406913 0.268619943722074 0.271541095954179 0.407311643931269 0.981105971769404 0.981105971769404
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Snrnp48 ENSMUSG00000021431 0.0602076772577112 0.0998693062174952 0.0665795374783302 0.0998693062174952 0.447787551416281 0.447787551416281
Ppwd1 ENSMUSG00000021713 0.23514399041173 0.352715985617596 0.154977936289727 0.352715985617596 0.993701178881087 0.993701178881087
Tra2b ENSMUSG00000022858 0.088046202952005 0.220666314363082 0.147110876242054 0.220666314363082 0.553621638058049 0.553621638058049
Ppil1 ENSMUSG00000024007 0.118153024895013 0.177229537342519 0.0989269831413781 0.177229537342519 0.874514514061034 0.874514514061034
Snrpc ENSMUSG00000024217 0.399452602234174 0.599178903351261 0.0791729691353165 0.237518907405949 0.766960921682776 0.766960921682776
Dhx16 ENSMUSG00000024422 0.615736992388526 0.615736992388526 0.371097173014268 0.615736992388526 0.44503429182454 0.615736992388526
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Syf2 ENSMUSG00000028821 0.566883581832035 0.599423435811525 0.303812450234357 0.599423435811525 0.599423435811525 0.599423435811525
Dhx15 ENSMUSG00000029169 0.241578490989996 0.664042271025446 0.652630589639779 0.664042271025446 0.664042271025446 0.664042271025446
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Lsm6 ENSMUSG00000031683 0.880785442527832 0.896377748432791 0.896377748432791 0.896377748432791 0.728324574258797 0.896377748432791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Nxt1 ENSMUSG00000036992 0.621284860765305 0.918244168391196 0.918244168391196 0.918244168391196 0.484109198446722 0.918244168391196
Bud31 ENSMUSG00000038722 0.981109110172814 0.981109110172814 0.438719695410828 0.981109110172814 0.890135118446842 0.981109110172814
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Thoc6 ENSMUSG00000041319 0.658299158938436 0.725211259395702 0.725211259395702 0.725211259395702 0.316993797124339 0.725211259395702
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Hnrnpf ENSMUSG00000042079 0.540445724277584 0.86833900748812 0.86833900748812 0.86833900748812 0.627198172521313 0.86833900748812
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Pcbp1 ENSMUSG00000051695 0.858995742172042 0.858995742172042 0.214016382460339 0.642049147381016 0.734151382873831 0.858995742172042
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Hnrnpm ENSMUSG00000059208 0.933937833575713 0.933937833575713 0.504472793220546 0.933937833575713 0.641274816047717 0.933937833575713
Ppih ENSMUSG00000060288 0.840461784423724 0.859025942688151 0.499420841868875 0.859025942688151 0.859025942688151 0.859025942688151
Wtap ENSMUSG00000060475 0.646954934744422 0.883895834956624 0.818937001818403 0.883895834956624 0.883895834956624 0.883895834956624
Prpf40a ENSMUSG00000061136 0.0246204871401498 0.0738614614204495 0.0850034502408037 0.127505175361206 0.824987758959212 0.824987758959212
Phf5a ENSMUSG00000061360 0.298149104107644 0.464734610518925 0.338644411753536 0.464734610518925 0.464734610518925 0.464734610518925
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Sarnp ENSMUSG00000078427 0.129072399107977 0.273145551583203 0.182097034388802 0.273145551583203 0.918249374405348 0.918249374405348
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Lsm5 ENSMUSG00000091625 0.877663587885737 0.877663587885737 0.443282927701248 0.689824377044141 0.459882918029427 0.689824377044141

Nucleotide Excision Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Yy1 ENSMUSG00000021264 0.393289234821783 0.883898254985362 0.883898254985362 0.883898254985362 0.764188125850636 0.883898254985362
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Chd1l ENSMUSG00000028089 0.698783983895017 0.698783983895017 0.233694116682994 0.698783983895017 0.646931914948733 0.698783983895017
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Zfp830 ENSMUSG00000046010 0.574968999682525 0.831211863248003 0.481959295162291 0.831211863248003 0.831211863248003 0.831211863248003
Ino80c ENSMUSG00000047989 0.761172578700378 0.877669131162382 0.877669131162382 0.877669131162382 0.404419970120681 0.877669131162382
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

AURKA Activation by TPX2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Hmmr ENSMUSG00000020330 0.50429506937531 0.756442604062965 0.861393672414444 0.861393672414444 0.297159974312533 0.756442604062965
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Tpx2 ENSMUSG00000027469 0.601043687283493 0.880309004500631 0.764092820268311 0.880309004500631 0.880309004500631 0.880309004500631
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847

TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfsf14 ENSMUSG00000005824 0.830497578891449 0.830497578891449 0.662134404606773 0.830497578891449 0.684388763123135 0.830497578891449
Cd40 ENSMUSG00000017652 0.643673827976474 0.781936089270423 0.781936089270423 0.781936089270423 0.336412302495068 0.781936089270423
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Ltb ENSMUSG00000024399 0.0658111875344749 0.197433562603425 0.572564291235266 0.780865448382835 0.780865448382835 0.780865448382835
Lta ENSMUSG00000024402 0.389055689700457 0.817767009433884 0.817767009433884 0.817767009433884 0.688424378604052 0.817767009433884
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Tnfsf13b ENSMUSG00000031497 0.915109392821947 0.915109392821947 0.758115970904928 0.915109392821947 0.328759998718564 0.915109392821947
Tnfrsf13c ENSMUSG00000068105 0.771782411234577 0.974450827684857 0.974450827684857 0.974450827684857 0.718920128986344 0.974450827684857
Tnfsf12 ENSMUSG00000097328 0.561531635206684 0.842297452810027 0.322979008125066 0.842297452810027 0.943358622315216 0.943358622315216

HDR through MMEJ (alt-NHEJ)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nbn ENSMUSG00000028224 0.0241416611540093 0.0724249834620279 0.290829770430793 0.436244655646189 0.952782615836134 0.952782615836134
Mre11a ENSMUSG00000031928 0.743183800949342 0.977959776175582 0.722396160898656 0.977959776175582 0.977959776175582 0.977959776175582
Polq ENSMUSG00000034206 0.757834625288544 0.971659899649896 0.971659899649896 0.971659899649896 0.843274394860513 0.971659899649896
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Rbbp8 ENSMUSG00000041238 0.046437431083447 0.139312293250341 0.309516989137309 0.464275483705963 0.955936768583559 0.955936768583559

DEx/H-box helicases activate type I IFN and inflammatory cytokines production

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Irf7 ENSMUSG00000025498 0.695919021442982 0.695919021442982 0.69269736647714 0.695919021442982 0.481640615368666 0.695919021442982
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524

Interleukin-35 Signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ebi3 ENSMUSG00000003206 0.965320343149152 0.965320343149152 0.243627680256872 0.730883040770617 0.794410637753496 0.965320343149152
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Il27ra ENSMUSG00000005465 0.361571871047973 0.542357806571959 0.609573072549827 0.609573072549827 0.250474922672147 0.542357806571959
Il12rb2 ENSMUSG00000018341 0.0650187340284855 0.195056202085457 0.252910280824245 0.379365421236367 0.870410338245282 0.870410338245282
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437

Phosphorylation of Emi1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333

Processive synthesis on the C-strand of the telomere

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Blm ENSMUSG00000030528 0.839294405657345 0.9272137172221 0.537167979300931 0.9272137172221 0.9272137172221 0.9272137172221
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

APC/C:Cdc20 mediated degradation of Securin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Metal sequestration by antimicrobial proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lcn2 ENSMUSG00000026822 0.254206613494242 0.597762311676581 0.815097344133041 0.815097344133041 0.398508207784387 0.597762311676581
Ltf ENSMUSG00000032496 0.407857077827021 0.407857077827021 0.352691902770801 0.407857077827021 0.24312638437072 0.407857077827021
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846

Unwinding of DNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gins1 ENSMUSG00000027454 0.562330959095825 0.843496438643737 0.35689311718598 0.843496438643737 0.886398234503072 0.886398234503072
Gins4 ENSMUSG00000031546 0.479319961047998 0.718979941571997 0.40218431251602 0.718979941571997 0.818818218349934 0.818818218349934
Gins3 ENSMUSG00000031669 0.748946828618625 0.846600546352046 0.846600546352046 0.846600546352046 0.748927769395932 0.846600546352046
Gins2 ENSMUSG00000031821 0.92127727885326 0.92127727885326 0.346625447026674 0.775085964274647 0.516723976183098 0.775085964274647

Transcriptional regulation by RUNX2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Aurka ENSMUSG00000027496 0.926464890799425 0.926464890799425 0.162545034565725 0.487635103697175 0.769833313021199 0.926464890799425
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Antiviral mechanism by IFN-stimulated genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Pde12 ENSMUSG00000043702 0.073424105599251 0.220272316797753 0.962224737253253 0.981105309298905 0.981105309298905 0.981105309298905
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142

Regulation of APC/C activators between G1/S and early anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Fbxo5 ENSMUSG00000019773 0.559947844648778 0.740059606527998 0.740059606527998 0.740059606527998 0.479671232076851 0.740059606527998
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214

p75 NTR receptor-mediated signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Gna13 ENSMUSG00000020611 0.82199964213225 0.82199964213225 0.646914959797738 0.82199964213225 0.797482446663473 0.82199964213225
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Fgd2 ENSMUSG00000024013 0.161857626162729 0.242786439244094 0.322838555032344 0.322838555032344 0.107991630713536 0.242786439244094
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Ect2 ENSMUSG00000027699 0.77792794697507 0.890086585145094 0.890086585145094 0.890086585145094 0.833265230652966 0.890086585145094
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Itgb3bp ENSMUSG00000028549 0.344775962239075 0.62659113806744 0.710518242047497 0.710518242047497 0.417727425378293 0.62659113806744
Arhgef19 ENSMUSG00000028919 0.607756072023105 0.911634108034657 0.0807069523274936 0.242120856982481 0.987400096134984 0.987400096134984
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Psenen ENSMUSG00000036835 0.203721213091886 0.30558181963783 0.062432064988998 0.187296194966994 0.391147422307809 0.391147422307809
Arhgef1 ENSMUSG00000040940 0.806675959017869 0.806675959017869 0.800572168566476 0.806675959017869 0.535247802570445 0.806675959017869
Arhgef10l ENSMUSG00000040964 0.196764129563487 0.350384610621833 0.233589740414555 0.350384610621833 0.585826905562777 0.585826905562777
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Adam17 ENSMUSG00000052593 0.18021850482087 0.54065551446261 0.424706107033476 0.610076476006283 0.610076476006283 0.610076476006283
Akap13 ENSMUSG00000066406 0.669623676240994 0.987398272706954 0.89324541901726 0.987398272706954 0.987398272706954 0.987398272706954
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Programmed Cell Death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Aven ENSMUSG00000003604 0.0568218852988106 0.105171764164122 0.0701145094427483 0.105171764164122 0.283742997975144 0.283742997975144
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Pdcd6ip ENSMUSG00000032504 0.684284110022022 0.959083659132617 0.540432638534207 0.959083659132617 0.959083659132617 0.959083659132617
Opa1 ENSMUSG00000038084 0.0613908214837045 0.144294521262819 0.0961963475085461 0.144294521262819 0.290915711029559 0.290915711029559
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Bmf ENSMUSG00000040093 0.0321896442752128 0.0965689328256384 0.132740178048105 0.199110267072158 0.216623427842839 0.216623427842839
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Hmgb2 ENSMUSG00000054717 0.911884435675714 0.949585440967289 0.849643762687026 0.949585440967289 0.949585440967289 0.949585440967289
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Stk24 ENSMUSG00000063410 0.993701986337495 0.993701986337495 0.357089045349694 0.993701986337495 0.896364584711293 0.993701986337495
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cross-presentation of soluble exogenous antigens (endosomes)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Fcgr1 ENSMUSG00000015947 0.580375731780965 0.580375731780965 0.16198970889556 0.485969126686681 0.365368162029342 0.548052243044013
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Mrc1 ENSMUSG00000026712 0.00501902805644276 0.0150570841693283 0.529795603712864 0.794693405569297 0.987402042597863 0.987402042597863
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212

Negative regulators of DDX58/IFIH1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nlrx1 ENSMUSG00000032109 0.000952664750264658 0.00285799425079397 0.0297302552242528 0.0445953828363792 0.607679466262999 0.607679466262999
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Ikbke ENSMUSG00000042349 0.752122139561209 0.761090703852877 0.761090703852877 0.761090703852877 0.280163617435584 0.761090703852877
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Caspase activation via Death Receptors in the presence of ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404

TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pard3 ENSMUSG00000025812 0.344777907710299 0.583454163725556 0.388969442483704 0.583454163725556 0.927675899565806 0.927675899565806
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

NF-kB is activated and signals survival

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

B-WICH complex positively regulates rRNA expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myo1c ENSMUSG00000017774 0.770207197610339 0.770207197610339 0.436310308243349 0.654465462365024 0.249676321659711 0.654465462365024
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Twistnb ENSMUSG00000020561 0.340750181790478 0.511125272685717 0.169426094457558 0.508278283372674 0.86831174199068 0.86831174199068
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Dek ENSMUSG00000021377 0.479308398166014 0.987399328842821 0.664102629729157 0.987399328842821 0.987399328842821 0.987399328842821
Polr1e ENSMUSG00000028318 0.649762019419188 0.852822858033419 0.535227950200136 0.852822858033419 0.852822858033419 0.852822858033419
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Taf1d ENSMUSG00000031939 0.148116238452801 0.43659102587211 0.29106068391474 0.43659102587211 0.865211912487404 0.865211912487404
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Znrd1 ENSMUSG00000036315 0.0821378908948957 0.246413672684687 0.203887954519348 0.305831931779022 0.32102217702293 0.32102217702293
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Polr1c ENSMUSG00000067148 0.519748758068391 0.63849341200239 0.594003694054131 0.63849341200239 0.63849341200239 0.63849341200239

Positive epigenetic regulation of rRNA expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myo1c ENSMUSG00000017774 0.770207197610339 0.770207197610339 0.436310308243349 0.654465462365024 0.249676321659711 0.654465462365024
Ddx21 ENSMUSG00000020075 0.494257245925 0.524683512642429 0.489379403431439 0.524683512642429 0.524683512642429 0.524683512642429
Twistnb ENSMUSG00000020561 0.340750181790478 0.511125272685717 0.169426094457558 0.508278283372674 0.86831174199068 0.86831174199068
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Dek ENSMUSG00000021377 0.479308398166014 0.987399328842821 0.664102629729157 0.987399328842821 0.987399328842821 0.987399328842821
Polr1e ENSMUSG00000028318 0.649762019419188 0.852822858033419 0.535227950200136 0.852822858033419 0.852822858033419 0.852822858033419
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Taf1d ENSMUSG00000031939 0.148116238452801 0.43659102587211 0.29106068391474 0.43659102587211 0.865211912487404 0.865211912487404
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Znrd1 ENSMUSG00000036315 0.0821378908948957 0.246413672684687 0.203887954519348 0.305831931779022 0.32102217702293 0.32102217702293
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Polr1c ENSMUSG00000067148 0.519748758068391 0.63849341200239 0.594003694054131 0.63849341200239 0.63849341200239 0.63849341200239

RUNX1 regulates transcription of genes involved in differentiation of HSCs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Tal1 ENSMUSG00000028717 0.803181825280339 0.803181825280339 0.324702995622202 0.803181825280339 0.687158429096566 0.803181825280339
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Lmo2 ENSMUSG00000032698 0.433970192533923 0.433970192533923 0.169427628688144 0.27104776367791 0.180698509118606 0.27104776367791
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

mRNA Splicing - Major Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0166694610077386 0.0500083830232158 0.924437275664023 0.924437275664023 0.593783146350941 0.890674719526412
Hnrnpa2b1 ENSMUSG00000004980 0.69886671783146 0.725341707588167 0.725341707588167 0.725341707588167 0.644149912834405 0.725341707588167
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Snrpb2 ENSMUSG00000008333 0.111876468464953 0.316247284683075 0.21083152312205 0.316247284683075 0.943361205125621 0.943361205125621
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Ccar1 ENSMUSG00000020074 0.0895399812406913 0.268619943722074 0.271541095954179 0.407311643931269 0.981105971769404 0.981105971769404
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Ppwd1 ENSMUSG00000021713 0.23514399041173 0.352715985617596 0.154977936289727 0.352715985617596 0.993701178881087 0.993701178881087
Tra2b ENSMUSG00000022858 0.088046202952005 0.220666314363082 0.147110876242054 0.220666314363082 0.553621638058049 0.553621638058049
Ppil1 ENSMUSG00000024007 0.118153024895013 0.177229537342519 0.0989269831413781 0.177229537342519 0.874514514061034 0.874514514061034
Snrpc ENSMUSG00000024217 0.399452602234174 0.599178903351261 0.0791729691353165 0.237518907405949 0.766960921682776 0.766960921682776
Dhx16 ENSMUSG00000024422 0.615736992388526 0.615736992388526 0.371097173014268 0.615736992388526 0.44503429182454 0.615736992388526
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Syf2 ENSMUSG00000028821 0.566883581832035 0.599423435811525 0.303812450234357 0.599423435811525 0.599423435811525 0.599423435811525
Dhx15 ENSMUSG00000029169 0.241578490989996 0.664042271025446 0.652630589639779 0.664042271025446 0.664042271025446 0.664042271025446
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Lsm6 ENSMUSG00000031683 0.880785442527832 0.896377748432791 0.896377748432791 0.896377748432791 0.728324574258797 0.896377748432791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Bud31 ENSMUSG00000038722 0.981109110172814 0.981109110172814 0.438719695410828 0.981109110172814 0.890135118446842 0.981109110172814
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Hnrnpf ENSMUSG00000042079 0.540445724277584 0.86833900748812 0.86833900748812 0.86833900748812 0.627198172521313 0.86833900748812
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Pcbp1 ENSMUSG00000051695 0.858995742172042 0.858995742172042 0.214016382460339 0.642049147381016 0.734151382873831 0.858995742172042
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Hnrnpm ENSMUSG00000059208 0.933937833575713 0.933937833575713 0.504472793220546 0.933937833575713 0.641274816047717 0.933937833575713
Ppih ENSMUSG00000060288 0.840461784423724 0.859025942688151 0.499420841868875 0.859025942688151 0.859025942688151 0.859025942688151
Prpf40a ENSMUSG00000061136 0.0246204871401498 0.0738614614204495 0.0850034502408037 0.127505175361206 0.824987758959212 0.824987758959212
Phf5a ENSMUSG00000061360 0.298149104107644 0.464734610518925 0.338644411753536 0.464734610518925 0.464734610518925 0.464734610518925
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Lsm5 ENSMUSG00000091625 0.877663587885737 0.877663587885737 0.443282927701248 0.689824377044141 0.459882918029427 0.689824377044141

DAP12 interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Siglecg ENSMUSG00000030468 0.247620943271295 0.742862829813885 0.95802095183943 0.95802095183943 0.941902228360924 0.95802095183943
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Cd300e ENSMUSG00000048498 0.362308350224987 0.804540447752196 0.857551973977173 0.857551973977173 0.536360298501464 0.804540447752196
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
Cd300lb ENSMUSG00000063193 0.0207312822843939 0.0621938468531818 0.570511330654218 0.661128772713596 0.661128772713596 0.661128772713596
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379

TNFR1-induced NFkappaB signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Gnb2l1 ENSMUSG00000020372 0.599362813972648 0.599362813972648 0.556064453494769 0.599362813972648 0.194011583926232 0.582034751778696
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Caspase activation via extrinsic apoptotic signalling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404

mRNA Splicing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0166694610077386 0.0500083830232158 0.924437275664023 0.924437275664023 0.593783146350941 0.890674719526412
Hnrnpa2b1 ENSMUSG00000004980 0.69886671783146 0.725341707588167 0.725341707588167 0.725341707588167 0.644149912834405 0.725341707588167
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Snrpb2 ENSMUSG00000008333 0.111876468464953 0.316247284683075 0.21083152312205 0.316247284683075 0.943361205125621 0.943361205125621
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Ccar1 ENSMUSG00000020074 0.0895399812406913 0.268619943722074 0.271541095954179 0.407311643931269 0.981105971769404 0.981105971769404
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Snrnp48 ENSMUSG00000021431 0.0602076772577112 0.0998693062174952 0.0665795374783302 0.0998693062174952 0.447787551416281 0.447787551416281
Ppwd1 ENSMUSG00000021713 0.23514399041173 0.352715985617596 0.154977936289727 0.352715985617596 0.993701178881087 0.993701178881087
Tra2b ENSMUSG00000022858 0.088046202952005 0.220666314363082 0.147110876242054 0.220666314363082 0.553621638058049 0.553621638058049
Ppil1 ENSMUSG00000024007 0.118153024895013 0.177229537342519 0.0989269831413781 0.177229537342519 0.874514514061034 0.874514514061034
Snrpc ENSMUSG00000024217 0.399452602234174 0.599178903351261 0.0791729691353165 0.237518907405949 0.766960921682776 0.766960921682776
Dhx16 ENSMUSG00000024422 0.615736992388526 0.615736992388526 0.371097173014268 0.615736992388526 0.44503429182454 0.615736992388526
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Ppie ENSMUSG00000028651 0.0514309229143301 0.15429276874299 0.883900391693456 0.883900391693456 0.200980965264093 0.30147144789614
Syf2 ENSMUSG00000028821 0.566883581832035 0.599423435811525 0.303812450234357 0.599423435811525 0.599423435811525 0.599423435811525
Dhx15 ENSMUSG00000029169 0.241578490989996 0.664042271025446 0.652630589639779 0.664042271025446 0.664042271025446 0.664042271025446
Isy1 ENSMUSG00000030056 0.80973610680446 0.968517398542739 0.669843987940593 0.968517398542739 0.968517398542739 0.968517398542739
Lsm6 ENSMUSG00000031683 0.880785442527832 0.896377748432791 0.896377748432791 0.896377748432791 0.728324574258797 0.896377748432791
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Bud31 ENSMUSG00000038722 0.981109110172814 0.981109110172814 0.438719695410828 0.981109110172814 0.890135118446842 0.981109110172814
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Hnrnpf ENSMUSG00000042079 0.540445724277584 0.86833900748812 0.86833900748812 0.86833900748812 0.627198172521313 0.86833900748812
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Pcbp1 ENSMUSG00000051695 0.858995742172042 0.858995742172042 0.214016382460339 0.642049147381016 0.734151382873831 0.858995742172042
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Hnrnpm ENSMUSG00000059208 0.933937833575713 0.933937833575713 0.504472793220546 0.933937833575713 0.641274816047717 0.933937833575713
Ppih ENSMUSG00000060288 0.840461784423724 0.859025942688151 0.499420841868875 0.859025942688151 0.859025942688151 0.859025942688151
Prpf40a ENSMUSG00000061136 0.0246204871401498 0.0738614614204495 0.0850034502408037 0.127505175361206 0.824987758959212 0.824987758959212
Phf5a ENSMUSG00000061360 0.298149104107644 0.464734610518925 0.338644411753536 0.464734610518925 0.464734610518925 0.464734610518925
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847
Lsm5 ENSMUSG00000091625 0.877663587885737 0.877663587885737 0.443282927701248 0.689824377044141 0.459882918029427 0.689824377044141

Degradation of AXIN

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Ovarian tumor domain proteases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rhoa ENSMUSG00000007815 0.504409109292446 0.698867965520293 0.434062632152079 0.698867965520293 0.698867965520293 0.698867965520293
Esr1 ENSMUSG00000019768 0.84973970125875 0.84973970125875 0.569622547903406 0.84973970125875 0.621642790007575 0.84973970125875
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Tnip1 ENSMUSG00000020400 0.893252516811798 0.893252516811798 0.646980449841827 0.893252516811798 0.849742702079745 0.893252516811798
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Trp53 ENSMUSG00000059552 0.227098932417857 0.592886889199152 0.395257926132768 0.592886889199152 0.660944986482899 0.660944986482899
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Fanconi Anemia Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fancl ENSMUSG00000004018 0.560801715774823 0.841202573662235 0.548089856730846 0.841202573662235 0.965299516532591 0.965299516532591
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ube2t ENSMUSG00000026429 0.812371394411998 0.84343594358458 0.84343594358458 0.84343594358458 0.840234771316459 0.84343594358458
Dclre1b ENSMUSG00000027845 0.0940441007317195 0.282132302195158 0.883895513132892 0.883895513132892 0.46476869742419 0.697153046136285
Usp1 ENSMUSG00000028560 0.434058003510885 0.94336484193188 0.687164372043649 0.94336484193188 0.94336484193188 0.94336484193188
C230052I12Rik ENSMUSG00000030493 0.426929509260589 0.542971452620046 0.235190764095948 0.542971452620046 0.542971452620046 0.542971452620046
Fanca ENSMUSG00000032815 0.893226156598959 0.940210255277229 0.69580320712939 0.940210255277229 0.940210255277229 0.940210255277229
Eme1 ENSMUSG00000039055 0.964885088051258 0.964885088051258 0.424510281992833 0.636765422989249 0.333072433185135 0.636765422989249
Fanci ENSMUSG00000039187 0.575451316965023 0.930750441583897 0.930750441583897 0.930750441583897 0.849985040178575 0.930750441583897
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Apitd1 ENSMUSG00000073705 0.610524624762158 0.915786937143237 0.248049644552839 0.744148933658518 0.99055395349967 0.99055395349967
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Interleukin-3, Interleukin-5 and GM-CSF signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hck ENSMUSG00000003283 0.113256530982693 0.33976959294808 0.632406387616348 0.632406387616348 0.51399391116552 0.632406387616348
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

G1 Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cyclin D associated events in G1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Cdk4 ENSMUSG00000006728 0.601966810810395 0.924505844747385 0.764135360210982 0.924505844747385 0.924505844747385 0.924505844747385
E2f4 ENSMUSG00000014859 0.618571027332006 0.927856540998009 0.49683839673254 0.927856540998009 1 1
E2f2 ENSMUSG00000018983 0.766255932080852 0.858312180463081 0.62660448877508 0.858312180463081 0.858312180463081 0.858312180463081
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
E2f1 ENSMUSG00000027490 0.843369424994199 0.984235670044172 0.649796277638992 0.984235670044172 0.984235670044172 0.984235670044172
Rbl1 ENSMUSG00000027641 0.632783991237969 0.910434788896842 0.910434788896842 0.910434788896842 0.728268429463518 0.910434788896842
Cks1b ENSMUSG00000028044 0.230048126925659 0.432069007042081 0.311065538276623 0.432069007042081 0.432069007042081 0.432069007042081
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
Ccnd3 ENSMUSG00000034165 0.693005711139945 0.693005711139945 0.120171704468637 0.360515113405912 0.540431008398455 0.693005711139945
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Initiation of Nuclear Envelope (NE) Reformation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lbr ENSMUSG00000004880 0.428673300308109 0.428673300308109 0.334752649488829 0.428673300308109 0.2238972919687 0.428673300308109
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935

TRAF6-mediated induction of TAK1 complex within TLR4 complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Hedgehog ligand biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Dhh ENSMUSG00000023000 0.338286542137345 0.576043386088313 0.5986642812318 0.5986642812318 0.384028924058875 0.576043386088313
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Hhat ENSMUSG00000037375 0.649356954558063 0.974797328816457 0.946426823413046 0.974797328816457 0.974797328816457 0.974797328816457
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Global Genome Nucleotide Excision Repair (GG-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Yy1 ENSMUSG00000021264 0.393289234821783 0.883898254985362 0.883898254985362 0.883898254985362 0.764188125850636 0.883898254985362
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Actl6a ENSMUSG00000027671 0.871308037685612 0.871308037685612 0.31311711678798 0.46967567518197 0.128949366001954 0.386848098005863
Chd1l ENSMUSG00000028089 0.698783983895017 0.698783983895017 0.233694116682994 0.698783983895017 0.646931914948733 0.698783983895017
Xpa ENSMUSG00000028329 0.740129846193341 0.959075295305341 0.646904439758579 0.959075295305341 0.959075295305341 0.959075295305341
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Gtf2h3 ENSMUSG00000029387 0.871449526087771 0.871449526087771 0.585798713570691 0.871449526087771 0.336764804670733 0.871449526087771
Actb ENSMUSG00000029580 0.499428229627924 0.64698188352353 0.232127830570856 0.64698188352353 0.64698188352353 0.64698188352353
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Ino80c ENSMUSG00000047989 0.761172578700378 0.877669131162382 0.877669131162382 0.877669131162382 0.404419970120681 0.877669131162382
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Base Excision Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pole ENSMUSG00000007080 0.281481707098945 0.844445121296835 0.890128145512554 0.890128145512554 0.785764488379165 0.890128145512554
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pole2 ENSMUSG00000020974 0.984191886740368 0.984191886740368 0.933865107900067 0.984191886740368 0.971533026365874 0.984191886740368
Rfc4 ENSMUSG00000022881 0.135378630949373 0.406135892848119 0.50189132862497 0.557583692171775 0.557583692171775 0.557583692171775
Rfc2 ENSMUSG00000023104 0.213789856254732 0.4047418712395 0.269827914159667 0.4047418712395 0.675431479476054 0.675431479476054
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Mutyh ENSMUSG00000028687 0.574867504158502 0.77019634576434 0.77019634576434 0.77019634576434 0.664040896456067 0.77019634576434
Rfc5 ENSMUSG00000029363 0.300185176591737 0.871447135483494 0.655514083959019 0.871447135483494 0.871447135483494 0.871447135483494
Ogg1 ENSMUSG00000030271 0.0442716123757612 0.132814837127284 0.438688139246743 0.658032208870115 0.734226035946159 0.734226035946159
Neil1 ENSMUSG00000032298 0.552851047579205 0.829276571368808 0.388947726176355 0.829276571368808 0.830863465675073 0.830863465675073
Rfc3 ENSMUSG00000033970 0.616080785383593 0.770226652244936 0.652675516371468 0.770226652244936 0.770226652244936 0.770226652244936
Parp2 ENSMUSG00000036023 0.840465756935555 0.880783170063337 0.880783170063337 0.880783170063337 0.585788155807246 0.880783170063337
H2afz ENSMUSG00000037894 0.553531397184701 0.96220138953511 0.96220138953511 0.96220138953511 0.855861329759184 0.96220138953511
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897
Neil3 ENSMUSG00000039396 0.993650763435805 0.993650763435805 0.943342252092692 0.993650763435805 0.908172903048363 0.993650763435805
H2afv ENSMUSG00000041126 0.122353664770863 0.183530497156294 0.121876602176667 0.183530497156294 0.640927568663085 0.640927568663085
Hist1h4i ENSMUSG00000060639 0.235237320178829 0.352855980268244 0.0447023829891216 0.134107148967365 0.752160436844301 0.752160436844301
Hist1h4c ENSMUSG00000060678 0.0402687509995446 0.120806252998634 0.746105183072495 0.927576357743992 0.927576357743992 0.927576357743992
Hist1h4d ENSMUSG00000061482 0.356437630091713 0.962026672007981 0.962026672007981 0.962026672007981 0.811776368725441 0.962026672007981
Hist1h2bj ENSMUSG00000069300 0.812440391037401 0.812440391037401 0.233729777075705 0.675141915413717 0.450094610275812 0.675141915413717
Hist1h4m ENSMUSG00000069306 0.852465001478908 0.852465001478908 0.319756486422962 0.724688148276246 0.483125432184164 0.724688148276246
Hist1h2bq ENSMUSG00000069307 0.757031570245459 0.757031570245459 0.553089940138845 0.757031570245459 0.61860129031676 0.757031570245459
Hist1h2bb ENSMUSG00000075031 0.519908080753638 0.519908080753638 0.0959459480258657 0.287837844077597 0.213874373111604 0.320811559667406

Negative regulation of FLT3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Sla ENSMUSG00000022372 0.138262809626666 0.414788428879997 0.728112347415511 0.946457422296594 0.946457422296594 0.946457422296594
Sla2 ENSMUSG00000027636 0.618611624131476 0.766707841294844 0.766707841294844 0.766707841294844 0.731971346679776 0.766707841294844
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Sh2b3 ENSMUSG00000042594 0.843477893509635 0.843477893509635 0.47949183846227 0.843477893509635 0.740074482594798 0.843477893509635
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
E2f7 ENSMUSG00000020185 0.665092250116085 0.839593971145153 0.0752611941969423 0.225783582590827 0.839593971145153 0.839593971145153
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Ccne2 ENSMUSG00000028212 0.244498590573453 0.585567809590951 0.406520794040459 0.585567809590951 0.585567809590951 0.585567809590951
E2f8 ENSMUSG00000046179 0.870753149447001 0.928676068795826 0.588260193709086 0.928676068795826 0.928676068795826 0.928676068795826

Removal of the Flap Intermediate from the C-strand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Terf1 ENSMUSG00000025925 0.764198679841777 0.887019872971696 0.887019872971696 0.887019872971696 0.607756794127549 0.887019872971696
Pcna ENSMUSG00000027342 0.574159946553625 0.629977900681358 0.629977900681358 0.629977900681358 0.550245456531944 0.629977900681358
Wrn ENSMUSG00000031583 0.788239687100881 0.788239687100881 0.47922640290279 0.788239687100881 0.704705995342403 0.788239687100881
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

Toll Like Receptor 2 (TLR2) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

SLBP independent Processing of Histone Pre-mRNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847

Toll Like Receptor TLR1:TLR2 Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll Like Receptor TLR6:TLR2 Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll Like Receptor 10 (TLR10) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

MyD88 cascade initiated on plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Toll Like Receptor 5 (TLR5) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vrk3 ENSMUSG00000002205 0.380190761336223 0.570286142004335 0.174395016047996 0.523185048143989 0.719444713614649 0.719444713614649
Rps6ka1 ENSMUSG00000003644 0.406645466283937 0.609968199425905 0.109169995411008 0.327509986233024 0.666969440167815 0.666969440167815
Ager ENSMUSG00000015452 0.48432190436518 0.866337681603159 0.893256355429595 0.893256355429595 0.577558454402106 0.866337681603159
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Nkiras2 ENSMUSG00000017837 0.638238404237282 0.638238404237282 0.257912058809466 0.638238404237282 0.514330736183047 0.638238404237282
Dusp6 ENSMUSG00000019960 0.61324897361287 0.61324897361287 0.378133804238763 0.567200706358144 0.378117143852475 0.567200706358144
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nfkbia ENSMUSG00000021025 0.0279529088700526 0.0838587266101578 0.116106705522374 0.174160058283561 0.206242286800324 0.206242286800324
Atf1 ENSMUSG00000023027 0.716462291333894 0.716485564565909 0.424693299517039 0.716485564565909 0.716485564565909 0.716485564565909
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Rela ENSMUSG00000024927 0.328727474134374 0.49309121120156 0.208092451579004 0.49309121120156 0.79447425701008 0.79447425701008
Nfkb2 ENSMUSG00000025225 0.912007837815783 0.912007837815783 0.222909250829534 0.668727752488602 0.911999421589877 0.912007837815783
Nfkb1 ENSMUSG00000028163 0.626899619734821 0.626899619734821 0.0565248273683574 0.138657977159912 0.0924386514399413 0.138657977159912
Nfkbib ENSMUSG00000030595 0.230471690108556 0.345707535162834 0.183448941962084 0.345707535162834 0.803591929242199 0.803591929242199
Mapkapk3 ENSMUSG00000032577 0.621648243762196 0.871453880060042 0.558937780279438 0.871453880060042 0.871453880060042 0.871453880060042
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of RUNX2 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

mRNA Splicing - Minor Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2a ENSMUSG00000005198 0.977959631014199 1 0.877669388655696 1 1 1
Lsm2 ENSMUSG00000007050 0.469680612258759 0.577663161598321 0.267947674423903 0.577663161598321 0.577663161598321 0.577663161598321
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Polr2h ENSMUSG00000021018 0.138370140612625 0.415110421837875 0.649829394118518 0.728316559866508 0.728316559866508 0.728316559866508
Snrnp48 ENSMUSG00000021431 0.0602076772577112 0.0998693062174952 0.0665795374783302 0.0998693062174952 0.447787551416281 0.447787551416281
Polr2f ENSMUSG00000033020 0.00513934946919156 0.0154180484075747 0.0180794250866947 0.0271191376300421 0.249677437067775 0.249677437067775
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Snrpd2 ENSMUSG00000040824 0.0111171032603216 0.0333513097809647 0.338752974348434 0.338752974348434 0.280295439337238 0.338752974348434
Polr2k ENSMUSG00000045996 0.285432788915236 0.365310264762505 0.166965002078865 0.365310264762505 0.365310264762505 0.365310264762505
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Gtf2f2 ENSMUSG00000067995 0.41341651813627 0.620124777204405 0.330761160442201 0.620124777204405 0.86212614713825 0.86212614713825
Snrnp40 ENSMUSG00000074088 0.369518021444009 0.583053519454617 0.583053519454617 0.583053519454617 0.582991257319755 0.583053519454617
Sf3b5 ENSMUSG00000078348 0.173142552695419 0.173142552695419 0.0336184901142589 0.100855470342777 0.160922276318687 0.173142552695419
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847

Interleukin-2 family signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Il9r ENSMUSG00000020279 0.567121998782706 0.567121998782706 0.444344190886413 0.567121998782706 0.0618307380274075 0.185492214082222
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Inpp5d ENSMUSG00000026288 0.899483779493708 0.899483779493708 0.393298770239466 0.5899481553592 0.104844509303909 0.314533527911728
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il21r ENSMUSG00000030745 0.393676827282235 0.776136584775257 0.776136584775257 0.776136584775257 0.695101662388114 0.776136584775257
Pik3cd ENSMUSG00000039936 0.558723114884889 0.607559833331183 0.371667149888 0.607559833331183 0.607559833331183 0.607559833331183
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574
Csf2rb2 ENSMUSG00000071714 0.687060332908656 0.896318149466159 0.896318149466159 0.896318149466159 0.307379801151127 0.896318149466159

Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Zfp36l1 ENSMUSG00000021127 0.344658554876765 0.56958665186549 0.537830619213933 0.56958665186549 0.56958665186549 0.56958665186549
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Pabpc1 ENSMUSG00000022283 0.264524330210481 0.793572990631443 0.996850021742696 0.996850021742696 0.987399078210607 0.996850021742696
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Exosc7 ENSMUSG00000025785 0.0902911688241303 0.270873506472391 0.855938250296372 0.855938250296372 0.484459752742404 0.726689629113606
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Exosc3 ENSMUSG00000028322 0.800401835468725 0.800401835468725 0.125074818368459 0.375224455105377 0.320609240122114 0.480913860183172
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Exosc5 ENSMUSG00000061286 0.00210892246404626 0.00316338369606939 0.000391908766013276 0.00117572629803983 0.734043951696963 0.734043951696963
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Degradation of GLI1 by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

ISG15 antiviral mechanism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.572019330571439 0.644016343092768 0.516984133522281 0.644016343092768 0.644016343092768 0.644016343092768
Mx2 ENSMUSG00000023341 0.466595737354001 0.466595737354001 0.164097270121733 0.304259334343721 0.202839556229148 0.304259334343721
Eif2ak2 ENSMUSG00000024079 0.550937956126765 0.826406934190148 0.373727096039168 0.826406934190148 0.918252131733712 0.918252131733712
Eif4e2 ENSMUSG00000026254 0.591180566613793 0.666883424951409 0.290913871293754 0.666883424951409 0.666883424951409 0.666883424951409
Ube2l6 ENSMUSG00000027078 0.955890747075864 0.955890747075864 0.782143490118549 0.955890747075864 0.265871199531113 0.797613598593339
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Uba7 ENSMUSG00000032596 0.40210428287683 0.641211921042192 0.440888590391152 0.641211921042192 0.641211921042192 0.641211921042192
Isg15 ENSMUSG00000035692 0.333894429115406 0.711462270702754 0.474308180468503 0.711462270702754 0.769973406056278 0.769973406056278
Ddx58 ENSMUSG00000040296 0.420190727578161 0.713446586468162 0.675473676949966 0.713446586468162 0.713446586468162 0.713446586468162
Eif4a1 ENSMUSG00000059796 0.666955033148101 0.937083750929689 0.937083750929689 0.937083750929689 0.36325977169465 0.937083750929689

Apoptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.737229923662269 0.792215516755384 0.778705974764405 0.792215516755384 0.792215516755384 0.792215516755384
Aven ENSMUSG00000003604 0.0568218852988106 0.105171764164122 0.0701145094427483 0.105171764164122 0.283742997975144 0.283742997975144
Bax ENSMUSG00000003873 0.300174666201888 0.450261999302832 0.199675375068415 0.450261999302832 0.644094533115148 0.644094533115148
Gzmb ENSMUSG00000015437 0.639360366053751 0.828075057589114 0.828075057589114 0.828075057589114 0.319310620541973 0.828075057589114
Apaf1 ENSMUSG00000019979 0.843431155555716 0.843431155555716 0.612989101359911 0.843431155555716 0.701720555337318 0.843431155555716
Prkcd ENSMUSG00000021948 0.840465792089203 0.840465792089203 0.54824017630325 0.840465792089203 0.629979737094272 0.840465792089203
Tnfrsf10b ENSMUSG00000022074 0.821979175784678 0.821979175784678 0.371764838756125 0.779578881431682 0.519719254287788 0.779578881431682
Rock1 ENSMUSG00000024290 0.175292448333624 0.525877345000872 0.687160366087815 0.818793848115364 0.818793848115364 0.818793848115364
Pmaip1 ENSMUSG00000024521 0.350695161682721 0.797514310756377 0.797514310756377 0.797514310756377 0.59110085530972 0.797514310756377
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Bcl2l11 ENSMUSG00000027381 0.809673638543362 0.937071751930326 0.937071751930326 0.937071751930326 0.504391801749865 0.937071751930326
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Opa1 ENSMUSG00000038084 0.0613908214837045 0.144294521262819 0.0961963475085461 0.144294521262819 0.290915711029559 0.290915711029559
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Bmf ENSMUSG00000040093 0.0321896442752128 0.0965689328256384 0.132740178048105 0.199110267072158 0.216623427842839 0.216623427842839
Clspn ENSMUSG00000042489 0.773815560306371 0.773815560306371 0.358658671718955 0.662153757217657 0.441435838145105 0.662153757217657
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Sfn ENSMUSG00000047281 0.386386545610352 0.654128218471092 0.436085478980728 0.654128218471092 0.905679912722804 0.905679912722804
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Hmgb2 ENSMUSG00000054717 0.911884435675714 0.949585440967289 0.849643762687026 0.949585440967289 0.949585440967289 0.949585440967289
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Bcl2 ENSMUSG00000057329 0.8250509858576 0.977959879509055 0.977959879509055 0.977959879509055 0.81582496082665 0.977959879509055
Bak1 ENSMUSG00000057789 0.809711739823772 0.809711739823772 0.532652567018012 0.809711739823772 0.803591262975039 0.809711739823772
Stk24 ENSMUSG00000063410 0.993701986337495 0.993701986337495 0.357089045349694 0.993701986337495 0.896364584711293 0.993701986337495
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456

Activation of NIMA Kinases NEK9, NEK6, NEK7

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333

G2/M DNA replication checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333

FLT3 Signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Cdkn1b ENSMUSG00000003031 0.60218834704746 0.89324483833369 0.89324483833369 0.89324483833369 0.484480371725159 0.89324483833369
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Sla ENSMUSG00000022372 0.138262809626666 0.414788428879997 0.728112347415511 0.946457422296594 0.946457422296594 0.946457422296594
Sla2 ENSMUSG00000027636 0.618611624131476 0.766707841294844 0.766707841294844 0.766707841294844 0.731971346679776 0.766707841294844
Csk ENSMUSG00000032312 0.580384872271185 0.870577308406778 0.455253735826136 0.870577308406778 0.896370775967396 0.896370775967396
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Sh2b3 ENSMUSG00000042594 0.843477893509635 0.843477893509635 0.47949183846227 0.843477893509635 0.740074482594798 0.843477893509635
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Degradation of DVL

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of RAS by GAPs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rasa4 ENSMUSG00000004952 0.812762425941407 0.812762425941407 0.474517018330885 0.798784778476808 0.532523185651206 0.798784778476808
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Rasal3 ENSMUSG00000052142 0.219834808678954 0.329752213018431 0.176391891555351 0.329752213018431 0.518499340692897 0.518499340692897
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

IKK complex recruitment mediated by RIP1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

GLI3 is processed to GLI3R by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

CD28 dependent Vav1 pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042

Interleukin-2 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Il2ra ENSMUSG00000026770 0.528300230855369 0.98725744452947 0.98725744452947 0.98725744452947 0.838008530858477 0.98725744452947
Il2rb ENSMUSG00000068227 0.499347474412383 0.749021211618574 0.873759613225594 0.873759613225594 0.48171804775824 0.749021211618574

Interleukin-10 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Il10ra ENSMUSG00000032089 0.291909116735114 0.291909116735114 0.0360519294382687 0.108155788314806 0.0992573695244427 0.148886054286664
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437

RUNX1 regulates transcription of genes involved in BCR signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pax5 ENSMUSG00000014030 0.0186093555017439 0.0558280665052318 0.204974322565396 0.307461483848093 0.657838226196952 0.657838226196952
Cbfb ENSMUSG00000031885 0.791318387377093 0.791318387377093 0.558778283996933 0.791318387377093 0.755062737917814 0.791318387377093
Elf2 ENSMUSG00000037174 0.843511612134173 0.843511612134173 0.402086839746097 0.843511612134173 0.627112152298218 0.843511612134173

NOD1/2 Signaling Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Casp1 ENSMUSG00000025888 0.577226675277415 0.577226675277415 0.144484972710067 0.313867108755964 0.209244739170643 0.313867108755964
Casp9 ENSMUSG00000028914 0.249533353661289 0.505031661420465 0.971666431434903 0.971666431434903 0.33668777428031 0.505031661420465
Casp2 ENSMUSG00000029863 0.494413006950816 0.741619510426225 0.831109984559981 0.831109984559981 0.36717391951834 0.741619510426225
Casp4 ENSMUSG00000033538 0.401422897981351 0.596123083268333 0.476965638813613 0.596123083268333 0.596123083268333 0.596123083268333
Nod1 ENSMUSG00000038058 0.0695311690752132 0.20859350722564 0.208088160238713 0.312132240358069 0.357045047848293 0.357045047848293
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Nod2 ENSMUSG00000055994 0.902609188135343 0.902609188135343 0.436165504446128 0.654248256669192 0.316990486745456 0.654248256669192
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

CD28 co-stimulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Map3k14 ENSMUSG00000020941 0.937064813082418 0.937064813082418 0.701773572948564 0.937064813082418 0.840407809727912 0.937064813082418
Pak2 ENSMUSG00000022781 0.755150261262006 0.755150261262006 0.484451983344888 0.755150261262006 0.731251136982651 0.755150261262006
Cd86 ENSMUSG00000022901 0.0132498538699969 0.0397495616099907 0.990543178035543 0.990543178035543 0.56682659672458 0.850239895086869
Map3k8 ENSMUSG00000024235 0.0760588524632058 0.114088278694809 0.345628192552122 0.345628192552122 0.058753270766971 0.114088278694809
Cd28 ENSMUSG00000026012 0.31653793824431 0.8208784992763 0.917801578412245 0.917801578412245 0.547252332850867 0.8208784992763
Them4 ENSMUSG00000028145 0.153778717005039 0.461336151015118 0.610465737405268 0.915698606107901 0.940224030723688 0.940224030723688
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Prr5 ENSMUSG00000036106 0.627180503561688 0.859030086342764 0.382427620187507 0.859030086342764 0.859030086342764 0.859030086342764
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Cd80 ENSMUSG00000075122 0.864888359352042 0.864888359352042 0.67783632499087 0.864888359352042 0.662884832559871 0.864888359352042

DAP12 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Lcp2 ENSMUSG00000002699 0.431412093489612 0.647118140234418 0.354972118182084 0.647118140234418 0.71639343814036 0.71639343814036
Vav2 ENSMUSG00000009621 0.296298931938896 0.888896795816688 0.927657766378473 0.990551461762012 0.990551461762012 0.990551461762012
H2-M3 ENSMUSG00000016206 0.690047655492576 0.886935001976351 0.886935001976351 0.886935001976351 0.106266782801363 0.31880034840409
Syk ENSMUSG00000021457 0.185812504257449 0.469664276432059 0.874547541078046 0.874547541078046 0.313109517621373 0.469664276432059
Klrk1 ENSMUSG00000030149 0.673715066560801 1 1 1 0.254252237103359 0.762756711310078
Klrd1 ENSMUSG00000030165 0.544738736379761 0.684074376300801 0.684074376300801 0.684074376300801 0.461856285001121 0.684074376300801
Klrc1 ENSMUSG00000030167 0.819786556681065 0.924455125371531 0.924455125371531 0.924455125371531 0.643093066329377 0.924455125371531
Tyrobp ENSMUSG00000030579 0.937062602552792 0.937062602552792 0.749100961890284 0.937062602552792 0.238377669618431 0.715133008855295
Lat ENSMUSG00000030742 0.0444092375668312 0.133227712700494 0.927664583027627 0.927664583027627 0.855649581465316 0.927664583027627
Btk ENSMUSG00000031264 0.19805290994031 0.594158729820931 0.72473028851494 0.72473028851494 0.541328433997937 0.72473028851494
Plcg2 ENSMUSG00000034330 0.933931995189786 0.933931995189786 0.342712950022109 0.583406694684909 0.388937796456606 0.583406694684909
H2-Q4 ENSMUSG00000035929 0.236742851058216 0.386804012293221 0.257869341528814 0.386804012293221 0.422367621759922 0.422367621759922
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
H2-Q7 ENSMUSG00000060550 0.613049588911079 0.613049588911079 0.501673169338284 0.613049588911079 0.218393941380463 0.613049588911079
H2-Q6 ENSMUSG00000073409 0.271454224141877 0.271454224141877 0.266160841855703 0.271454224141877 0.267978440845166 0.271454224141877
H2-T10 ENSMUSG00000079491 0.290550426685586 0.435825640028379 0.818726440316246 0.818726440316246 0.280996143272079 0.435825640028379

Loss of Nlp from mitotic centrosomes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

Loss of proteins required for interphase microtubule organization from the centrosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

Regulation of ornithine decarboxylase (ODC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Oaz1 ENSMUSG00000035242 0.000245430716924225 0.00038697599196905 0.000257983994646033 0.00038697599196905 0.0303905902078832 0.0303905902078832
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212

Degradation of beta-catenin by the destruction complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcf7 ENSMUSG00000000782 0.357568316079733 0.815360931552631 0.782261556624813 0.815360931552631 0.815360931552631 0.815360931552631
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Ppp2r5a ENSMUSG00000026626 0.43173046491662 0.64759569737493 0.305770558255241 0.64759569737493 0.943365694207013 0.943365694207013
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Lef1 ENSMUSG00000027985 0.383771678645834 0.548691327976703 0.548691327976703 0.548691327976703 0.489528574699393 0.548691327976703
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Tle3 ENSMUSG00000032280 0.675618863935546 0.908879028654204 0.569597050555408 0.908879028654204 0.908879028654204 0.908879028654204
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

APC-Cdc20 mediated degradation of Nek2A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Mad2l1 ENSMUSG00000029910 0.577652400880864 0.883889063221076 0.618844234111986 0.883889063221076 0.883889063221076 0.883889063221076
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Bub1b ENSMUSG00000040084 0.447921672638985 0.812748875139756 0.621576040375659 0.812748875139756 0.812748875139756 0.812748875139756
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of TNFR1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Gnb2l1 ENSMUSG00000020372 0.599362813972648 0.599362813972648 0.556064453494769 0.599362813972648 0.194011583926232 0.582034751778696
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Fam105b ENSMUSG00000046034 0.0843703839428626 0.244470642610515 0.16298042840701 0.244470642610515 0.993696907141791 0.993696907141791
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Regulation of TLR by endogenous ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Tlr1 ENSMUSG00000044827 0.278829708321117 0.836489124963352 0.718902957831314 0.964944650744324 0.964944650744324 0.964944650744324
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Tlr6 ENSMUSG00000051498 0.180256623489696 0.270384935234544 0.428794853170176 0.428794853170176 0.0899565530077903 0.269869659023371
S100a8 ENSMUSG00000056054 0.943269485593287 0.943269485593287 0.166021075702054 0.498063227106162 0.521451146193105 0.782176719289657
S100a9 ENSMUSG00000056071 0.269373553603287 0.404060330404931 0.128425554156763 0.385276662470289 0.933809881900846 0.933809881900846
Hmgb1 ENSMUSG00000066551 0.395243307055943 0.592864960583914 0.191112408317821 0.573337224953463 0.752096151580456 0.752096151580456

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Ube2d3 ENSMUSG00000078578 0.054691444681762 0.164074334045286 0.378122697458351 0.567184046187527 0.827934897601085 0.827934897601085
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

p75NTR recruits signalling complexes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Ngf ENSMUSG00000027859 0.644141067137358 0.791433071345118 0.791433071345118 0.791433071345118 0.613285030129485 0.791433071345118
Myd88 ENSMUSG00000032508 0.764179282917569 0.764179282917569 0.098904984486985 0.296714953460955 0.367228823879016 0.550843235818524
Ripk2 ENSMUSG00000041135 0.0625407037145215 0.187622111143564 0.743121731104666 0.749114780144993 0.749114780144993 0.749114780144993
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mitotic Telophase/Cytokinesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kif20a ENSMUSG00000003779 0.509191474801519 0.675657706977439 0.579124624735322 0.675657706977439 0.675657706977439 0.675657706977439
Nipbl ENSMUSG00000022141 0.161825980309516 0.485477940928549 0.632857913764817 0.80050193145693 0.80050193145693 0.80050193145693
Stag2 ENSMUSG00000025862 0.462491038410299 0.693736557615449 0.127068372028643 0.381205116085929 0.767211943459017 0.767211943459017
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Kif23 ENSMUSG00000032254 0.252754408877693 0.758263226633079 0.825030526847702 0.825030526847702 0.764051383744927 0.825030526847702
Wapal ENSMUSG00000041408 0.2182446047097 0.654733814129099 0.893258369353548 0.893258369353548 0.545516006645871 0.818274009968807

TNF signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tab2 ENSMUSG00000015755 0.479343133726555 1 0.791402779089026 1 1 1
Tnfaip3 ENSMUSG00000019850 0.593836087328901 0.785294547069378 0.695910499741299 0.785294547069378 0.785294547069378 0.785294547069378
Gnb2l1 ENSMUSG00000020372 0.599362813972648 0.599362813972648 0.556064453494769 0.599362813972648 0.194011583926232 0.582034751778696
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Sharpin ENSMUSG00000022552 0.213745180020793 0.641235540062379 0.678466991965001 0.678466991965001 0.63822141464265 0.678466991965001
Tnf ENSMUSG00000024401 0.278637768445439 0.295482608017129 0.179850123514004 0.295482608017129 0.295482608017129 0.295482608017129
Traf1 ENSMUSG00000026875 0.615976390800985 0.649697968355183 0.649697968355183 0.649697968355183 0.192625674140569 0.577877022421706
Traf2 ENSMUSG00000026942 0.292834276921617 0.649757051509648 0.474606741669998 0.649757051509648 0.649757051509648 0.649757051509648
Tradd ENSMUSG00000031887 0.577588415127505 0.86212171121467 0.672708744683043 0.86212171121467 0.86212171121467 0.86212171121467
Fam105b ENSMUSG00000046034 0.0843703839428626 0.244470642610515 0.16298042840701 0.244470642610515 0.993696907141791 0.993696907141791
Adam17 ENSMUSG00000052593 0.18021850482087 0.54065551446261 0.424706107033476 0.610076476006283 0.610076476006283 0.610076476006283
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Cyclin A/B1/B2 associated events during G2/M transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Pkmyt1 ENSMUSG00000023908 0.698844000787601 0.949643015327676 0.949643015327676 0.949643015327676 0.943355249605444 0.949643015327676
Cdk2 ENSMUSG00000025358 0.427109244158649 0.837366469760533 0.791403712405852 0.837366469760533 0.837366469760533 0.837366469760533
Ccna2 ENSMUSG00000027715 0.671956651151357 0.930807403639297 0.930807403639297 0.930807403639297 0.93059728714514 0.930807403639297
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Cdc25a ENSMUSG00000032477 0.51187968713338 0.743017617514503 0.266402778619723 0.743017617514503 0.743017617514503 0.743017617514503
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdc25c ENSMUSG00000044201 0.708768938865325 0.961936823768456 0.961936823768456 0.961936823768456 0.437176084908586 0.961936823768456

Interferon alpha/beta signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf9 ENSMUSG00000002325 0.273215205287827 0.81964561586348 0.886920080255498 0.886920080255498 0.610148261034508 0.886920080255498
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Ifnar1 ENSMUSG00000022967 0.773097229182205 0.797403097290578 0.797403097290578 0.797403097290578 0.678392281012349 0.797403097290578
Ifnar2 ENSMUSG00000022971 0.574838247704471 0.862257371556707 0.545663981139693 0.862257371556707 0.974808103287817 0.974808103287817
Usp18 ENSMUSG00000030107 0.76414477063194 0.843339043164632 0.7044221024565 0.843339043164632 0.843339043164632 0.843339043164632
Tyk2 ENSMUSG00000032175 0.467306765033306 0.593993631931437 0.574969469796706 0.593993631931437 0.593993631931437 0.593993631931437
Socs1 ENSMUSG00000038037 0.452383633036709 0.678575449555064 0.0480580619348262 0.144174185804479 0.974739378168747 0.974739378168747
Socs3 ENSMUSG00000053113 0.350220915618061 0.874375504043315 0.707296559955163 0.874375504043315 0.874375504043315 0.874375504043315
Rnasel ENSMUSG00000066800 0.716363467865142 0.716363467865142 0.44107090105954 0.716363467865142 0.638317870290853 0.716363467865142

PINK1-PRKN Mediated Mitophagy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.965372553252154 0.965372553252154 0.602243125863618 0.965372553252154 0.794474616019644 0.965372553252154
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Mterfd1 ENSMUSG00000021519 0.582981523718819 0.582981523718819 0.209604037472405 0.582981523718819 0.411078752225781 0.582981523718819
Tomm22 ENSMUSG00000022427 0.149124924658535 0.223687386987802 0.129966230687846 0.223687386987802 0.517108572504206 0.517108572504206
Map1lc3a ENSMUSG00000027602 0.216931527037847 0.529097628306715 0.352731752204477 0.529097628306715 0.737173277632261 0.737173277632261
Pink1 ENSMUSG00000028756 0.114631020653944 0.171946530980916 0.0625166258415864 0.171946530980916 0.618833611848092 0.618833611848092
Tomm7 ENSMUSG00000028998 0.0580537350048442 0.0870806025072663 0.0449526634592287 0.0870806025072663 0.290540239342445 0.290540239342445
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa3 ENSMUSG00000012483 0.877634286812182 0.877634286812182 0.629940133393774 0.877634286812182 0.261289229839286 0.783867689517858
Pold2 ENSMUSG00000020471 0.0887249480030719 0.266174844009216 0.431731547094008 0.647597320641012 0.955938528016496 0.955938528016496
Pold4 ENSMUSG00000024854 0.11276839027254 0.178806434573497 0.119204289715665 0.178806434573497 0.420244663235443 0.420244663235443
Pold1 ENSMUSG00000038644 0.408855149231265 0.613282723846897 0.641318863904816 0.641318863904816 0.402188684531387 0.613282723846897

TRIF-mediated programmed cell death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk3 ENSMUSG00000022221 0.880765250035625 0.883795566964865 0.883795566964865 0.883795566964865 0.79732562904238 0.883795566964865
Tlr4 ENSMUSG00000039005 0.00246981834669164 0.00740945504007491 0.111513348197884 0.167270022296826 0.852797452837826 0.852797452837826
Ticam1 ENSMUSG00000047123 0.719424154057192 0.952789331415393 0.561513516652001 0.952789331415393 0.952789331415393 0.952789331415393
Cd14 ENSMUSG00000051439 0.199644923354817 0.598934770064452 0.806404339498586 0.806404339498586 0.660870249137916 0.806404339498586
Ticam2 ENSMUSG00000056130 0.0156834976135999 0.0470504928407997 0.142789476835841 0.214184215253762 0.366416076692404 0.366416076692404

Inhibition of replication initiation of damaged DNA by RB1/E2F1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267

E2F mediated regulation of DNA replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pola1 ENSMUSG00000006678 0.681153561951198 0.927628592566736 0.267901330245557 0.803703990736672 0.927628592566736 0.927628592566736
Rb1 ENSMUSG00000022105 0.519731812726756 0.871457351537924 0.788388098644181 0.871457351537924 0.871457351537924 0.871457351537924
Pola2 ENSMUSG00000024833 0.47990486263522 0.602956261283992 0.132406658515506 0.397219975546518 0.602956261283992 0.602956261283992
Prim1 ENSMUSG00000025395 0.940205894734222 0.940205894734222 0.905743341104827 0.940205894734222 0.930800350814929 0.940205894734222
Prim2 ENSMUSG00000026134 0.73702840388969 0.815700039222267 0.3824138720879 0.815700039222267 0.815700039222267 0.815700039222267

Nuclear Envelope Breakdown

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup50 ENSMUSG00000016619 0.965360561401329 0.965360561401329 0.422437541800474 0.965360561401329 0.905715156028584 0.965360561401329
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Vrk1 ENSMUSG00000021115 0.545648529845918 0.868342634810476 0.868342634810476 0.868342634810476 0.649807451391316 0.868342634810476
Lmnb1 ENSMUSG00000024590 0.666792755395791 0.862086376224385 0.569602616351044 0.862086376224385 0.862086376224385 0.862086376224385
Banf1 ENSMUSG00000024844 0.110013092291467 0.330039276874402 0.251121189340964 0.376681784011446 0.406426332622762 0.406426332622762
Sec13 ENSMUSG00000030298 0.535192209568741 0.802788314353111 0.930797020207291 0.930797020207291 0.216888121402155 0.650664364206464
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Ccnb2 ENSMUSG00000032218 0.882971108307531 0.882971108307531 0.10479881573674 0.31439644721022 0.638678941035262 0.882971108307531
Nup37 ENSMUSG00000035351 0.0554255265854504 0.166276579756351 0.48447778227146 0.48447778227146 0.163315216922315 0.244972825383473
Aaas ENSMUSG00000036678 0.375854329266591 0.563781493899886 0.0872499953207243 0.261749985962173 0.599293095585901 0.599293095585901
Nup43 ENSMUSG00000040034 0.773104262195914 0.773104262195914 0.604897435083094 0.773104262195914 0.678377176431868 0.773104262195914
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Nup160 ENSMUSG00000051329 0.773185057917295 0.896368014205853 0.896368014205853 0.896368014205853 0.758096330085564 0.896368014205853
Vrk2 ENSMUSG00000064090 0.695915148030935 0.695915148030935 0.417841614651057 0.695915148030935 0.484473580434387 0.695915148030935

Asymmetric localization of PCP proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

RNA Polymerase II Transcription Termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Ddx39 ENSMUSG00000005481 0.266365938779284 0.532596299455637 0.369580486206305 0.532596299455637 0.532596299455637 0.532596299455637
Srsf6 ENSMUSG00000016921 0.558811050164352 0.838216575246528 0.397639654092249 0.838216575246528 0.984254186125981 0.984254186125981
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Alyref ENSMUSG00000025134 0.877624601033369 0.915078108323901 0.755143033014401 0.915078108323901 0.915078108323901 0.915078108323901
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Magoh ENSMUSG00000028609 0.846613494520974 0.846613494520974 0.776259201016316 0.846613494520974 0.506911568544609 0.846613494520974
Srsf2 ENSMUSG00000034120 0.543019859165547 0.800498068445487 0.550871763054325 0.800498068445487 0.800498068445487 0.800498068445487
Thoc6 ENSMUSG00000041319 0.658299158938436 0.725211259395702 0.725211259395702 0.725211259395702 0.316993797124339 0.725211259395702
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
U2af1 ENSMUSG00000061613 0.254513482402147 0.407331879763799 0.271554586509199 0.407331879763799 0.737163151613013 0.737163151613013
Sarnp ENSMUSG00000078427 0.129072399107977 0.273145551583203 0.182097034388802 0.273145551583203 0.918249374405348 0.918249374405348
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847

Downregulation of TGF-beta receptor signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.30362819661302 0.68098752582066 0.68098752582066 0.68098752582066 0.672472268452919 0.68098752582066
Tgfbr1 ENSMUSG00000007613 0.17297812036089 0.518934361082669 0.955848922859343 0.955848922859343 0.914948090943194 0.955848922859343
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Smad7 ENSMUSG00000025880 0.649798395621747 0.896376264313015 0.761168517994278 0.896376264313015 0.896376264313015 0.896376264313015
Tgfbr2 ENSMUSG00000032440 0.390861873335699 0.390861873335699 0.10912375456493 0.327371263694791 0.296515157668464 0.390861873335699
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

Signaling by SCF-KIT

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.426917859335947 0.825079624105794 0.825079624105794 0.825079624105794 0.737105852519948 0.825079624105794
Stat3 ENSMUSG00000004040 0.713538356229777 0.713538356229777 0.399968812610551 0.713538356229777 0.58852618528116 0.713538356229777
Stat5a ENSMUSG00000004043 0.289103658755777 0.365359569706363 0.365359569706363 0.365359569706363 0.363336616387005 0.365359569706363
Ptpn6 ENSMUSG00000004266 0.974805723285406 0.974805723285406 0.504102457239597 0.756153685859395 0.44322411672972 0.756153685859395
Grap ENSMUSG00000004837 0.00343653481082032 0.0103096044324609 0.26654119597006 0.39981179395509 0.473780913066103 0.473780913066103
Mmp9 ENSMUSG00000017737 0.946374152349152 0.946374152349152 0.695233748058376 0.946374152349152 0.742766944105164 0.946374152349152
Chek1 ENSMUSG00000032113 0.287348649711514 0.607657708332507 0.607657708332507 0.607657708332507 0.60492492691096 0.607657708332507
Vav1 ENSMUSG00000034116 0.457455028606667 0.678275632084631 0.264120611964677 0.678275632084631 0.678275632084631 0.678275632084631
Lyn ENSMUSG00000042228 0.125012464145118 0.375037392435353 0.757806873055192 0.757806873055192 0.637925254612703 0.757806873055192
Grap2 ENSMUSG00000042351 0.213001141208009 0.639003423624027 0.712486744049048 0.712486744049048 0.705983151455662 0.712486744049048
Sh2b3 ENSMUSG00000042594 0.843477893509635 0.843477893509635 0.47949183846227 0.843477893509635 0.740074482594798 0.843477893509635
Fes ENSMUSG00000053158 0.955918350698691 0.955918350698691 0.138316211723927 0.282688434232086 0.188458956154724 0.282688434232086

Metabolism of polyamines

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb4 ENSMUSG00000005779 0.000424598380049875 0.00127379514014962 0.00679029646186809 0.0101854446928021 0.119953089584379 0.119953089584379
Psmb1 ENSMUSG00000014769 0.698836480634693 0.698836480634693 0.27988260063306 0.698836480634693 0.604641863056954 0.698836480634693
Psma2 ENSMUSG00000015671 0.149288296269588 0.447864888808765 0.987398309324107 0.987398309324107 0.467089736060161 0.700634604090241
Psme1 ENSMUSG00000022216 0.285649826681657 0.551192739303022 0.367461826202015 0.551192739303022 0.607705233904727 0.607705233904727
Psmb8 ENSMUSG00000024338 0.749137155458486 0.757773983774759 0.757773983774759 0.757773983774759 0.41508122591046 0.757773983774759
Sat1 ENSMUSG00000025283 0.880765012104803 0.968512840389037 0.968512840389037 0.968512840389037 0.675617428747568 0.968512840389037
Psma7 ENSMUSG00000027566 0.367524651435973 0.367524651435973 0.298313120509169 0.367524651435973 0.110084684471714 0.330254053415141
Psmb2 ENSMUSG00000028837 0.902533280431711 0.902533280431711 0.0849445527742943 0.127416829161441 0.0341289939611966 0.10238698188359
Psma1 ENSMUSG00000030751 0.737228978103469 0.737228978103469 0.207961437697696 0.623884313093089 0.46232910793008 0.69349366189512
Psmd10 ENSMUSG00000031429 0.905750380806703 0.927674739965599 0.927674739965599 0.927674739965599 0.678500971293272 0.927674739965599
Psmb10 ENSMUSG00000031897 0.675606971803825 0.927628624840304 0.927628624840304 0.927628624840304 0.638337400043435 0.927628624840304
Oaz1 ENSMUSG00000035242 0.000245430716924225 0.00038697599196905 0.000257983994646033 0.00038697599196905 0.0303905902078832 0.0303905902078832
Psma8 ENSMUSG00000036743 0.968472987468422 0.968472987468422 0.739594896938954 0.968472987468422 0.773106532362513 0.968472987468422
Psma3 ENSMUSG00000060073 0.210667543851687 0.632002631555061 0.67809451592721 0.840165154260521 0.840165154260521 0.840165154260521
Psma5 ENSMUSG00000068749 0.110936969478088 0.332810908434265 0.921379923124471 0.921379923124471 0.4133252331711 0.61998784975665
Psme2b ENSMUSG00000078153 0.707298310917648 0.707298310917648 0.445567143965419 0.668350715948128 0.205961695762888 0.617885087288665
Psme2 ENSMUSG00000079197 0.210980396039722 0.62982457884212 0.62982457884212 0.62982457884212 0.519610669441837 0.62982457884212

Centrosome maturation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

Recruitment of mitotic centrosome proteins and complexes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Cep72 ENSMUSG00000021572 0.890081580570867 0.962205240205 0.962205240205 0.962205240205 0.514520436580498 0.962205240205
Haus4 ENSMUSG00000022177 0.0912321550237463 0.273696465071239 0.35070817551632 0.417291390949808 0.417291390949808 0.417291390949808
Nde1 ENSMUSG00000022678 0.987399770932852 0.987399770932852 0.208176529849689 0.38397462668254 0.255983084455026 0.38397462668254
Cep192 ENSMUSG00000024542 0.725358133013432 0.734252572368946 0.734252572368946 0.734252572368946 0.725357485471782 0.734252572368946
Plk4 ENSMUSG00000025758 0.79426629917292 0.858902946739329 0.616021558679894 0.858902946739329 0.858902946739329 0.858902946739329
Nek2 ENSMUSG00000026622 0.465581788394981 0.698372682592471 0.209542885955411 0.628628657866232 0.965287074938889 0.965287074938889
Cdk11b ENSMUSG00000029062 0.98110751585686 0.98110751585686 0.965374589314995 0.98110751585686 0.880780421793136 0.98110751585686
Plk1 ENSMUSG00000030867 0.769149179099146 0.892667776499473 0.36496229173174 0.892667776499473 0.892667776499473 0.892667776499473
Haus7 ENSMUSG00000031371 0.150387781266274 0.415043853853585 0.276695902569056 0.415043853853585 0.725304960491569 0.725304960491569
Cep57 ENSMUSG00000031922 0.940217314133877 0.940217314133877 0.0766034710576513 0.229810413172954 0.770205626058847 0.940217314133877
Haus6 ENSMUSG00000038047 0.484467424071216 0.726701136106824 0.479336688978179 0.726701136106824 0.899448539345902 0.899448539345902
Haus1 ENSMUSG00000041840 0.162127836942278 0.486383510826833 0.927676374663672 0.927676374663672 0.630038143749788 0.927676374663672
Cep110 ENSMUSG00000057110 0.80961526398167 0.80961526398167 0.408789995537731 0.80961526398167 0.553513830474935 0.80961526398167
Cenpj ENSMUSG00000064128 0.443034796823451 0.962201854042362 0.740058597888694 0.962201854042362 0.962201854042362 0.962201854042362
Cep152 ENSMUSG00000068394 0.661208025022558 0.731221605124087 0.564207642780482 0.731221605124087 0.731221605124087 0.731221605124087
Fgfr1op ENSMUSG00000069135 0.728278868147817 0.905705349788014 0.522074189933369 0.905705349788014 0.905705349788014 0.905705349788014
Cep76 ENSMUSG00000073542 0.12239365847508 0.367180975425241 0.265825475012174 0.398738212518261 0.958214748263285 0.958214748263285
Haus5 ENSMUSG00000078762 0.194062544637681 0.291093816956522 0.779242648929125 0.779242648929125 0.184646018934523 0.291093816956522
Haus3 ENSMUSG00000079555 0.219868204763076 0.544782173173576 0.36318811544905 0.544782173173576 0.883872772730875 0.883872772730875

Processing of Capped Intronless Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slbp ENSMUSG00000004642 0.629819292453846 0.968517936112693 0.968517936112693 0.968517936112693 0.818835275645788 0.968517936112693
Snrpf ENSMUSG00000020018 0.758142282107044 1 0.946507564636303 1 1 1
Snrpd3 ENSMUSG00000020180 0.156127422278453 0.468382266835359 0.87766449600467 0.87766449600467 0.489413021368074 0.734119532052111
Clp1 ENSMUSG00000027079 0.556270586753596 0.588547022392207 0.336764317559376 0.588547022392207 0.588547022392207 0.588547022392207
Cstf1 ENSMUSG00000027498 0.358766616712458 0.358766616712458 0.0641841950902537 0.192552585270761 0.213812655161824 0.320718982742736
Pcf11 ENSMUSG00000041328 0.23514882578874 0.705446477366221 0.646936070611625 0.965361663686899 0.965361663686899 0.965361663686899
Zfp473 ENSMUSG00000048012 0.262868373120132 0.788605119360396 0.914928041801345 0.914928041801345 0.60960710030706 0.91441065046059
Lsm10 ENSMUSG00000050188 0.143787130890936 0.215680696336404 0.0208062059820856 0.0624186179462569 0.224283450555235 0.224283450555235
Snrpg ENSMUSG00000057278 0.0216825369876829 0.0557014667618953 0.0371343111745969 0.0557014667618953 0.24304114952858 0.24304114952858
Snrpe ENSMUSG00000090553 0.0636096884034109 0.190829065210233 0.174399858914486 0.261599788371729 0.417758247305847 0.417758247305847

APC/C:Cdc20 mediated degradation of Cyclin B

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.763731639588596 0.763731639588596 0.250958270859962 0.46696807280064 0.31131204853376 0.46696807280064
Cdc20 ENSMUSG00000006398 0.0902699061039492 0.135404859155924 0.00887302663385551 0.0266190799015665 0.45876188358976 0.45876188358976
Cdk1 ENSMUSG00000019942 0.109143656077626 0.327430968232879 0.915023312668872 0.915023312668872 0.46362403595453 0.695436053931796
Rps27a ENSMUSG00000020460 0.16570341123106 0.497110233693182 0.927672251468551 0.927672251468551 0.47953400757939 0.719301011369084
Anapc15 ENSMUSG00000030649 0.486504685733485 0.858909318918604 0.858909318918604 0.858909318918604 0.618825967973836 0.858909318918604
Ccnb1 ENSMUSG00000041431 0.458787567277277 0.688181350915916 0.458650266066975 0.688181350915916 0.965118914468333 0.965118914468333
Cdc26 ENSMUSG00000066149 0.621500714790214 0.621500714790214 0.170632705196517 0.511898115589552 0.504360042746974 0.621500714790214
Gm11808 ENSMUSG00000068240 0.0787546778433608 0.236264033530082 0.438717492796148 0.438717492796148 0.168195025729273 0.25229253859391
Uba52 ENSMUSG00000090137 0.382443285543537 0.530038369712126 0.530038369712126 0.530038369712126 0.460076605641117 0.530038369712126

darkolivegreen

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Car4 ENSMUSG00000000805 0.868341265495093 0.868341265495093 0.75816782586753 0.868341265495093 0.666960278638366 0.868341265495093
Agpat3 ENSMUSG00000001211 0.731192092416326 0.731192092416326 0.106449390102905 0.319348170308714 0.230363270220595 0.345544905330892
Itpkc ENSMUSG00000003752 0.132122608287715 0.396367824863144 0.273206597295387 0.409809895943081 0.506970347759577 0.506970347759577
Ggt1 ENSMUSG00000006345 0.484322295578906 0.918226932301916 0.852764372242287 0.918226932301916 0.918226932301916 0.918226932301916
Aprt ENSMUSG00000006589 0.164477209052713 0.49343162715814 0.3653789019609 0.548068352941349 0.574970666443981 0.574970666443981
Neu1 ENSMUSG00000007038 0.61879264316566 0.984253153889948 0.684251668796809 0.984253153889948 0.984253153889948 0.984253153889948
Plcd1 ENSMUSG00000010660 0.0581193783522371 0.174358135056711 0.572259016322503 0.572259016322503 0.395533324361179 0.572259016322503
Apip ENSMUSG00000010911 0.265823003197018 0.265823003197018 0.0149439892027555 0.0448319676082665 0.242624203241981 0.265823003197018
Aldh1a3 ENSMUSG00000015134 0.641018032688078 0.883536630191276 0.883536630191276 0.883536630191276 0.378490261396125 0.883536630191276
Ada ENSMUSG00000017697 0.40651664223584 0.965825270082217 0.990544366083357 0.990544366083357 0.643883513388145 0.965825270082217
Aoc3 ENSMUSG00000019326 0.680456846597119 0.990522279821747 0.660657868426263 0.990522279821747 0.990522279821747 0.990522279821747
Smpd2 ENSMUSG00000019822 0.0183912729291572 0.0551738187874714 0.779142223607204 0.87449186937348 0.87449186937348 0.87449186937348
Mgat4c ENSMUSG00000019888 0.446192023708245 0.974113511481092 0.778229020140517 0.974113511481092 0.974113511481092 0.974113511481092
Hkdc1 ENSMUSG00000020080 0.971461542987442 0.971475336205523 0.971475336205523 0.971475336205523 0.647653438592168 0.971475336205523
Ddc ENSMUSG00000020182 0.591245347109318 0.831233453001025 0.427081878005525 0.831233453001025 0.831233453001025 0.831233453001025
Upp1 ENSMUSG00000020407 0.53438933974896 0.751958251909793 0.751958251909793 0.751958251909793 0.635021407721474 0.751958251909793
Aspa ENSMUSG00000020774 0.946510409134041 0.946510409134041 0.583066195958908 0.928249183025496 0.618832788683664 0.928249183025496
Nos2 ENSMUSG00000020826 0.429305971041944 0.726576330918685 0.540486478523281 0.726576330918685 0.726576330918685 0.726576330918685
Sptlc2 ENSMUSG00000021036 0.262904682003909 0.767829662437442 0.511886441624961 0.767829662437442 0.776152833206285 0.776152833206285
Arg2 ENSMUSG00000021125 0.532564995330278 0.698702944257651 0.46234208571082 0.698702944257651 0.698702944257651 0.698702944257651
Degs2 ENSMUSG00000021263 0.724164730722854 0.739451628849382 0.739451628849382 0.739451628849382 0.546609578577222 0.739451628849382
Ptdss1 ENSMUSG00000021518 0.877656701788645 0.877656701788645 0.0405081128048405 0.121524338414522 0.661030660177479 0.877656701788645
Elovl7 ENSMUSG00000021696 0.6957322516322 0.946357994156981 0.74258336929697 0.946357994156981 0.946357994156981 0.946357994156981
Cryl1 ENSMUSG00000021947 0.624442662917326 0.791441740103188 0.791441740103188 0.791441740103188 0.630051756529549 0.791441740103188
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Tsta3 ENSMUSG00000022570 0.0367365312689306 0.110209593806792 0.462501201214523 0.583063795513227 0.583063795513227 0.583063795513227
Pycrl ENSMUSG00000022571 0.382415151018369 0.818905364971026 0.818905364971026 0.818905364971026 0.613296570850605 0.818905364971026
Adcy6 ENSMUSG00000022994 0.076687927976775 0.230063783930325 0.19522296530981 0.292834447964714 0.752067769804379 0.752067769804379
Cndp2 ENSMUSG00000024644 0.846642053526538 0.846642053526538 0.436332591839893 0.654498887759839 0.427054766727121 0.654498887759839
Rfk ENSMUSG00000024712 0.943360952543614 0.943360952543614 0.0288562081812464 0.0865686245437393 0.776263968195261 0.943360952543614
Asah2 ENSMUSG00000024887 0.981087628957424 0.981087628957424 0.769990243472496 0.981087628957424 0.678404091653036 0.981087628957424
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Aldh18a1 ENSMUSG00000025007 0.990547717285726 0.990547717285726 0.307566228065496 0.922698684196487 0.752035704634922 0.990547717285726
Maoa ENSMUSG00000025037 0.943358186549532 0.943358186549532 0.512073520332203 0.943358186549532 0.937072719959207 0.943358186549532
Gsto1 ENSMUSG00000025068 0.632662654199987 0.632662654199987 0.123060414533276 0.369181243599829 0.593768647994058 0.632662654199987
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Pycr1 ENSMUSG00000025140 0.977958666479294 0.977958666479294 0.632800375855301 0.949200563782951 0.452864274515534 0.949200563782951
Cant1 ENSMUSG00000025575 0.402172302162049 0.603258453243073 0.393362699237923 0.603258453243073 0.693008868680827 0.693008868680827
Mgat4a ENSMUSG00000026110 0.701674145717133 0.701674145717133 0.477075371669908 0.701674145717133 0.561421445143131 0.701674145717133
Lct ENSMUSG00000026354 0.940901610906142 0.940901610906142 0.712662196408685 0.940901610906142 0.710720986002554 0.940901610906142
Bpnt1 ENSMUSG00000026617 0.821990260155696 0.821990260155696 0.443439463546384 0.821990260155696 0.776260465807766 0.821990260155696
Uap1 ENSMUSG00000026670 0.0477776206832073 0.143332862049622 0.868294756250759 0.868294756250759 0.356980409125785 0.535470613688678
St6galnac6 ENSMUSG00000026811 0.740221592894354 0.933943501145503 0.42019228812206 0.933943501145503 0.933943501145503 0.933943501145503
Galnt3 ENSMUSG00000026994 0.987400304476363 0.987400304476363 0.666853256647925 0.987400304476363 0.454804061333491 0.987400304476363
Ivd ENSMUSG00000027332 0.00851885708117468 0.025556571243524 0.350899246864757 0.352903319267405 0.352903319267405 0.352903319267405
Lpin3 ENSMUSG00000027412 0.350877233309094 0.526315849963642 0.800516748498999 0.800516748498999 0.276725908369913 0.526315849963642
Car13 ENSMUSG00000027555 0.725133987085329 0.968485576703039 0.968485576703039 0.968485576703039 0.719102929403769 0.968485576703039
Mecom ENSMUSG00000027684 0.301436159695384 0.615209123127327 0.962173690867563 0.962173690867563 0.410139415418218 0.615209123127327
Pld1 ENSMUSG00000027695 0.616027987400436 0.918270497702046 0.918270497702046 0.918270497702046 0.233677903782894 0.701033711348682
Sis ENSMUSG00000027790 0.427897360197622 0.465382249983061 0.465382249983061 0.465382249983061 0.224766927643762 0.465382249983061
Car9 ENSMUSG00000028463 0.83416222003248 0.921380859905091 0.469156993920399 0.921380859905091 0.921380859905091 0.921380859905091
Akr1a1 ENSMUSG00000028692 0.175669161597978 0.527007484793935 0.38028546057159 0.570428190857386 0.782294421562961 0.782294421562961
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Plb1 ENSMUSG00000029134 0.519954693773021 0.779932040659531 0.952980447169958 0.952980447169958 0.363005787285086 0.779932040659531
Pgm1 ENSMUSG00000029171 0.219923142229254 0.659769426687761 0.716357308829155 0.716357308829155 0.457508869905054 0.686263304857581
Agpat9 ENSMUSG00000029314 0.0856777155669593 0.257033146700878 0.618686808543379 0.785289842664283 0.785289842664283 0.785289842664283
Tpk1 ENSMUSG00000029735 0.616036151017144 0.831193775685723 0.831193775685723 0.831193775685723 0.621562319800369 0.831193775685723
Aoc1 ENSMUSG00000029811 0.692750079162274 0.858193949287853 0.858193949287853 0.858193949287853 0.719945683390129 0.858193949287853
Gfpt1 ENSMUSG00000029992 0.322940567966185 0.921407679645115 0.921407679645115 0.921407679645115 0.755165907034892 0.921407679645115
Acadsb ENSMUSG00000030861 0.76112479409503 0.76112479409503 0.388871781094042 0.76112479409503 0.758177245704243 0.76112479409503
Mtm1 ENSMUSG00000031337 0.718734043101403 0.718734043101403 0.373628407431785 0.718734043101403 0.539477560053959 0.718734043101403
Ido1 ENSMUSG00000031551 0.246899479807979 0.703634444422564 0.703634444422564 0.703634444422564 0.527028737621969 0.703634444422564
Galnt7 ENSMUSG00000031608 0.169335132385826 0.508005397157478 0.767119791588071 0.98110373090371 0.98110373090371 0.98110373090371
Got2 ENSMUSG00000031672 0.260499903899206 0.390749855848809 0.0374574057899824 0.112372217369947 0.454800218425187 0.454800218425187
B3gnt3 ENSMUSG00000031803 0.890105010732863 0.890105010732863 0.142482916164533 0.427448748493599 0.455018379120772 0.682527568681158
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Treh ENSMUSG00000032098 0.838661956349351 0.851393617154574 0.434881406136461 0.851393617154574 0.851393617154574 0.851393617154574
Bckdhb ENSMUSG00000032263 0.262892472475128 0.788677417425383 0.535179883315182 0.802769824972773 0.890135020932439 0.890135020932439
Nt5e ENSMUSG00000032420 0.834298925036398 0.834298925036398 0.635313755157743 0.834298925036398 0.83108749140236 0.834298925036398
Stt3b ENSMUSG00000032437 0.373745029720233 0.880743235405161 0.690111840365796 0.880743235405161 0.880743235405161 0.880743235405161
Sgpp2 ENSMUSG00000032908 0.977792051611679 0.977792051611679 0.664091401167753 0.977792051611679 0.814818803342026 0.977792051611679
Pla2g4c ENSMUSG00000033847 0.230250324084723 0.404422750661083 0.303860573015806 0.404422750661083 0.404422750661083 0.404422750661083
Aldh1b1 ENSMUSG00000035561 0.326676432587271 0.481819208398872 0.281881712659348 0.481819208398872 0.481819208398872 0.481819208398872
Mgat4b ENSMUSG00000036620 0.448064690454459 0.666929466583634 0.025977731687055 0.077933195061165 0.666929466583634 0.666929466583634
Galnt6 ENSMUSG00000037280 0.734243232682629 0.734243232682629 0.602195408694262 0.734243232682629 0.481949492250282 0.734243232682629
Atp6v0a2 ENSMUSG00000038023 0.90260447954445 0.90260447954445 0.103952826131909 0.311858478395727 0.788375339111343 0.90260447954445
Gmds ENSMUSG00000038372 0.701723443319335 0.952780102682691 0.361186146827202 0.952780102682691 0.952780102682691 0.952780102682691
Mboat1 ENSMUSG00000038732 0.767161864604521 0.767161864604521 0.646812478218905 0.767161864604521 0.352627939276744 0.767161864604521
Anpep ENSMUSG00000039062 0.760984716137745 0.760984716137745 0.326448666750582 0.760984716137745 0.574784252911429 0.760984716137745
Tph1 ENSMUSG00000040046 0.938155113543858 0.938155113543858 0.713314649498837 0.938155113543858 0.445903249141294 0.938155113543858
Gyltl1b ENSMUSG00000040434 0.669460190448817 0.836777586878077 0.836777586878077 0.836777586878077 0.721541597642914 0.836777586878077
Cyp2s1 ENSMUSG00000040703 0.803605682920622 0.946505656123509 0.946505656123509 0.946505656123509 0.940211175269926 0.946505656123509
B4galnt3 ENSMUSG00000041372 0.626554432728926 0.846521313437084 0.721906536873215 0.846521313437084 0.846521313437084 0.846521313437084
Pde3a ENSMUSG00000041741 0.481386816722574 0.987393284158312 0.865193327753376 0.987393284158312 0.987393284158312 0.987393284158312
Gucy2c ENSMUSG00000042638 0.946220990503486 0.946220990503486 0.676410510755997 0.946220990503486 0.744213808756341 0.946220990503486
Gpx2 ENSMUSG00000042808 0.52005294694811 0.588925433863524 0.588925433863524 0.588925433863524 0.562486809357912 0.588925433863524
Akr1b7 ENSMUSG00000052131 0.939153572947976 0.996792474614302 0.952040528311447 0.996792474614302 0.996792474614302 0.996792474614302
Ppap2c ENSMUSG00000052151 0.455290201122185 0.666978670869125 0.303936474764992 0.666978670869125 0.666978670869125 0.666978670869125
Pde5a ENSMUSG00000053965 0.514541087912636 0.987405397178174 0.987405397178174 0.987405397178174 0.837371520671081 0.987405397178174
Lclat1 ENSMUSG00000054469 0.200983748863478 0.602951246590435 0.80973518982499 0.80973518982499 0.621591708076235 0.80973518982499
Fut2 ENSMUSG00000055978 0.694699667972788 0.817371478377464 0.817371478377464 0.817371478377464 0.684131790430368 0.817371478377464
St3gal5 ENSMUSG00000056091 0.93080461359939 0.93080461359939 0.206712406396208 0.620137219188626 0.687170397241485 0.93080461359939
Pgm3 ENSMUSG00000056131 0.794438413901895 0.794438413901895 0.558892648149637 0.794438413901895 0.776219665474985 0.794438413901895
Rdh9 ENSMUSG00000056148 0.84946365448375 0.84946365448375 0.731193969736957 0.84946365448375 0.612495202864568 0.84946365448375
Cndp1 ENSMUSG00000056162 0.914699295505607 0.977702702684528 0.427643346373822 0.977702702684528 0.977702702684528 0.977702702684528
Fhit ENSMUSG00000060579 0.25285059246879 0.654177180370668 0.436118120247112 0.654177180370668 0.952783495608441 0.952783495608441
Ipmk ENSMUSG00000060733 0.324800937479879 0.679345324553285 0.452896883035524 0.679345324553285 0.990551398440706 0.990551398440706
Ext1 ENSMUSG00000061731 0.713543892033136 0.713543892033136 0.553606875091365 0.713543892033136 0.630019519345084 0.713543892033136
Pnp2 ENSMUSG00000068417 0.869736414789005 0.869736414789005 0.657959824756308 0.869736414789005 0.60296868525153 0.869736414789005
B3gnt6 ENSMUSG00000074004 0.977876207817531 0.977876207817531 0.827890587351799 0.977876207817531 0.600640521017228 0.977876207817531
Mgst2 ENSMUSG00000074604 0.977879126168875 0.977879126168875 0.508732217037025 0.977879126168875 0.949349329530891 0.977879126168875
Ugt1a7c ENSMUSG00000090124 0.459422054799653 0.854146325779094 0.955882693645803 0.955882693645803 0.569430883852729 0.854146325779094
Gcnt4 ENSMUSG00000091387 0.981078221363129 0.981078221363129 0.930803750314257 0.981078221363129 0.886832830838805 0.981078221363129

Mineral absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc26a3 ENSMUSG00000001225 0.57469303476021 0.862039552140315 0.983929188570735 0.983929188570735 0.2534310281605 0.7602930844815
Slc5a1 ENSMUSG00000011034 0.88791075718043 0.888264024504141 0.746563448002747 0.888264024504141 0.888264024504141 0.888264024504141
Steap1 ENSMUSG00000015652 0.473694645043305 0.641376131583104 0.433411057074385 0.641376131583104 0.641376131583104 0.641376131583104
Slc6a19 ENSMUSG00000021565 1 1 0.582902829398259 0.874354244097389 0.486780613861072 0.874354244097389
Vdr ENSMUSG00000022479 0.993679418704703 0.993679418704703 0.914875070162745 0.993679418704703 0.549921416892069 0.993679418704703
Slc26a6 ENSMUSG00000023259 0.0427744564776817 0.128323369433045 0.104504514943076 0.156756772414614 0.532449303840237 0.532449303840237
Trpm6 ENSMUSG00000024727 0.961603977289231 0.961603977289231 0.936520548644379 0.961603977289231 0.448300978809613 0.961603977289231
Slc34a2 ENSMUSG00000029188 0.463545808152237 0.899397094493345 0.899397094493345 0.899397094493345 0.811062715960212 0.899397094493345
Heph ENSMUSG00000031209 0.883802096989625 0.977960187040556 0.977960187040556 0.977960187040556 0.390801752810548 0.977960187040556
Atp1a1 ENSMUSG00000033161 0.809730083674155 0.840467268521411 0.388958929735072 0.840467268521411 0.840467268521411 0.840467268521411
Slc9a3 ENSMUSG00000036123 0.477231542692887 0.71584731403933 0.966584200819459 0.966584200819459 0.377614390638735 0.71584731403933
Slc39a4 ENSMUSG00000063354 0.74387061428507 0.880328935168269 0.880328935168269 0.880328935168269 0.873303209257354 0.880328935168269

NOD-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk13 ENSMUSG00000004864 0.247175966779255 0.741527900337765 0.597662543357616 0.895897917326185 0.895897917326185 0.895897917326185
Mcu ENSMUSG00000009647 0.566929882017194 0.903347710135193 0.602231806756795 0.903347710135193 0.968519313290455 0.968519313290455
Naip1 ENSMUSG00000021640 0.814118010485166 0.885400627279693 0.642444930105069 0.885400627279693 0.885400627279693 0.885400627279693
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Nek7 ENSMUSG00000026393 0.585733804123183 0.825072360163331 0.761136076641176 0.825072360163331 0.825072360163331 0.825072360163331
Card9 ENSMUSG00000026928 0.858790135086326 0.858790135086326 0.445797309138566 0.678311856135324 0.452207904090216 0.678311856135324
Panx1 ENSMUSG00000031934 0.725335407450183 0.952796044130063 0.76116021488702 0.952796044130063 0.952796044130063 0.952796044130063
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Naip5 ENSMUSG00000071203 0.199852686715507 0.299779030073261 0.320715567714059 0.320715567714059 0.112604219897842 0.299779030073261
Defa-rs1 ENSMUSG00000074437 0.739684236453104 0.739684236453104 0.204637842121166 0.613913526363499 0.510778019501324 0.739684236453104
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Defa22 ENSMUSG00000074443 0.363740929460835 0.482633287130785 0.359902425938571 0.482633287130785 0.482633287130785 0.482633287130785
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Naip6 ENSMUSG00000078942 0.0450502514906726 0.135150754472018 0.984077384184586 0.984077384184586 0.273804058756168 0.410706088134253
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm21002 ENSMUSG00000094362 0.235672427721343 0.70701728316403 0.930664408413975 0.930664408413975 0.585046519074805 0.877569778612207
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Staphylococcus aureus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Krt19 ENSMUSG00000020911 0.745128929192169 0.784963714297712 0.478565997746831 0.784963714297712 0.784963714297712 0.784963714297712
Krt20 ENSMUSG00000035775 0.352479491418878 0.528719237128317 0.242621548568001 0.528719237128317 0.651522352133256 0.651522352133256
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Defa-rs1 ENSMUSG00000074437 0.739684236453104 0.739684236453104 0.204637842121166 0.613913526363499 0.510778019501324 0.739684236453104
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Defa22 ENSMUSG00000074443 0.363740929460835 0.482633287130785 0.359902425938571 0.482633287130785 0.482633287130785 0.482633287130785
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm21002 ENSMUSG00000094362 0.235672427721343 0.70701728316403 0.930664408413975 0.930664408413975 0.585046519074805 0.877569778612207
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Glycerolipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Agpat3 ENSMUSG00000001211 0.731192092416326 0.731192092416326 0.106449390102905 0.319348170308714 0.230363270220595 0.345544905330892
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Lpin3 ENSMUSG00000027412 0.350877233309094 0.526315849963642 0.800516748498999 0.800516748498999 0.276725908369913 0.526315849963642
Akr1a1 ENSMUSG00000028692 0.175669161597978 0.527007484793935 0.38028546057159 0.570428190857386 0.782294421562961 0.782294421562961
Agpat9 ENSMUSG00000029314 0.0856777155669593 0.257033146700878 0.618686808543379 0.785289842664283 0.785289842664283 0.785289842664283
Aldh1b1 ENSMUSG00000035561 0.326676432587271 0.481819208398872 0.281881712659348 0.481819208398872 0.481819208398872 0.481819208398872
Mboat1 ENSMUSG00000038732 0.767161864604521 0.767161864604521 0.646812478218905 0.767161864604521 0.352627939276744 0.767161864604521
Akr1b7 ENSMUSG00000052131 0.939153572947976 0.996792474614302 0.952040528311447 0.996792474614302 0.996792474614302 0.996792474614302
Ppap2c ENSMUSG00000052151 0.455290201122185 0.666978670869125 0.303936474764992 0.666978670869125 0.666978670869125 0.666978670869125
Mogat2 ENSMUSG00000052396 0.627771507062674 0.627771507062674 0.155748554566206 0.467245663698618 0.345327788768269 0.517991683152404
Lclat1 ENSMUSG00000054469 0.200983748863478 0.602951246590435 0.80973518982499 0.80973518982499 0.621591708076235 0.80973518982499

Arginine and proline metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nos2 ENSMUSG00000020826 0.429305971041944 0.726576330918685 0.540486478523281 0.726576330918685 0.726576330918685 0.726576330918685
Arg2 ENSMUSG00000021125 0.532564995330278 0.698702944257651 0.46234208571082 0.698702944257651 0.698702944257651 0.698702944257651
Pycrl ENSMUSG00000022571 0.382415151018369 0.818905364971026 0.818905364971026 0.818905364971026 0.613296570850605 0.818905364971026
Cndp2 ENSMUSG00000024644 0.846642053526538 0.846642053526538 0.436332591839893 0.654498887759839 0.427054766727121 0.654498887759839
Aldh18a1 ENSMUSG00000025007 0.990547717285726 0.990547717285726 0.307566228065496 0.922698684196487 0.752035704634922 0.990547717285726
Maoa ENSMUSG00000025037 0.943358186549532 0.943358186549532 0.512073520332203 0.943358186549532 0.937072719959207 0.943358186549532
Pycr1 ENSMUSG00000025140 0.977958666479294 0.977958666479294 0.632800375855301 0.949200563782951 0.452864274515534 0.949200563782951
Aoc1 ENSMUSG00000029811 0.692750079162274 0.858193949287853 0.858193949287853 0.858193949287853 0.719945683390129 0.858193949287853
Got2 ENSMUSG00000031672 0.260499903899206 0.390749855848809 0.0374574057899824 0.112372217369947 0.454800218425187 0.454800218425187
Aldh1b1 ENSMUSG00000035561 0.326676432587271 0.481819208398872 0.281881712659348 0.481819208398872 0.481819208398872 0.481819208398872
Cndp1 ENSMUSG00000056162 0.914699295505607 0.977702702684528 0.427643346373822 0.977702702684528 0.977702702684528 0.977702702684528

Transcriptional misregulation in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tmprss2 ENSMUSG00000000385 0.380859858266217 0.987157538953525 0.666229008678204 0.987157538953525 0.987157538953525 0.987157538953525
Jup ENSMUSG00000001552 0.190060250508939 0.295328587106757 0.196885724737838 0.295328587106757 0.943368515910083 0.943368515910083
Cdkn1a ENSMUSG00000023067 0.00953777499198078 0.0286133249759424 0.170440615742981 0.255660923614472 0.890070458203683 0.890070458203683
Spint1 ENSMUSG00000027315 0.410699198147399 0.911935712761414 0.855883808833477 0.911935712761414 0.911935712761414 0.911935712761414
Prom1 ENSMUSG00000029086 0.613205446471854 0.871395277791367 0.803584771888625 0.871395277791367 0.871395277791367 0.871395277791367
Nupr1 ENSMUSG00000030717 0.905750873107791 0.905750873107791 0.494249127960556 0.850155099842196 0.566770066561464 0.850155099842196
Maf ENSMUSG00000055435 0.148220049582771 0.444660148748313 0.952786708730182 0.952786708730182 0.53519873752356 0.80279810628534
Hmga2 ENSMUSG00000056758 0.290577376205056 0.700468546926089 0.700468546926089 0.700468546926089 0.47058122519506 0.700468546926089
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Defa-rs1 ENSMUSG00000074437 0.739684236453104 0.739684236453104 0.204637842121166 0.613913526363499 0.510778019501324 0.739684236453104
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Defa22 ENSMUSG00000074443 0.363740929460835 0.482633287130785 0.359902425938571 0.482633287130785 0.482633287130785 0.482633287130785
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm21002 ENSMUSG00000094362 0.235672427721343 0.70701728316403 0.930664408413975 0.930664408413975 0.585046519074805 0.877569778612207
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Protein digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc7a7 ENSMUSG00000000958 0.174420391969767 0.261630587954651 0.303467860454927 0.303467860454927 0.12368397467234 0.261630587954651
Kcnq1 ENSMUSG00000009545 0.964926596959531 0.964926596959531 0.467612567243953 0.758003492250036 0.505335661500024 0.758003492250036
Ace2 ENSMUSG00000015405 0.962108950722947 0.984187840896465 0.984187840896465 0.984187840896465 0.788032438214414 0.984187840896465
Slc6a19 ENSMUSG00000021565 1 1 0.582902829398259 0.874354244097389 0.486780613861072 0.874354244097389
Kcnk5 ENSMUSG00000023243 0.669672904169353 0.669672904169353 0.64952079591149 0.669672904169353 0.486413377513204 0.669672904169353
Mep1a ENSMUSG00000023914 0.593594116242276 0.593594116242276 0.0601329731301296 0.180398919390389 0.4525289975816 0.593594116242276
Mep1b ENSMUSG00000024313 0.745425295384824 0.745425295384824 0.437070743447031 0.745425295384824 0.70106603085664 0.745425295384824
Slc15a1 ENSMUSG00000025557 0.701230330178935 0.99003672266318 0.99003672266318 0.99003672266318 0.941460073281463 0.99003672266318
Slc7a9 ENSMUSG00000030492 0.960748588186069 0.960748588186069 0.498264459931539 0.747396689897308 0.31636548300845 0.747396689897308
Col6a4 ENSMUSG00000032572 0.447462645611263 0.879371298887196 0.863961037631135 0.879371298887196 0.879371298887196 0.879371298887196
Atp1a1 ENSMUSG00000033161 0.809730083674155 0.840467268521411 0.388958929735072 0.840467268521411 0.840467268521411 0.840467268521411
Kcne3 ENSMUSG00000035165 0.283824424178439 0.654544629580847 0.436363086387231 0.654544629580847 0.937083344296334 0.937083344296334
Slc9a3 ENSMUSG00000036123 0.477231542692887 0.71584731403933 0.966584200819459 0.966584200819459 0.377614390638735 0.71584731403933
Xpnpep2 ENSMUSG00000037005 0.817858326941608 0.817858326941608 0.420585738004824 0.817858326941608 0.571309758641193 0.817858326941608

Renin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ace ENSMUSG00000020681 0.843566002851484 0.946498031963005 0.236770056266123 0.710310168798369 0.946498031963005 0.946498031963005
Edn1 ENSMUSG00000021367 0.551461145887251 0.551461145887251 0.164974271443126 0.247461407164689 0.146191318940917 0.247461407164689
Adcy6 ENSMUSG00000022994 0.076687927976775 0.230063783930325 0.19522296530981 0.292834447964714 0.752067769804379 0.752067769804379
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Edn3 ENSMUSG00000027524 0.486937463497489 0.933949137826282 0.661224422465519 0.933949137826282 0.933949137826282 0.933949137826282
Clca3 ENSMUSG00000028255 0.0620660984862553 0.186198295458766 0.565160266906818 0.576720033453063 0.576720033453063 0.576720033453063
Clca2 ENSMUSG00000028262 0.717349003668636 0.752678649695706 0.752678649695706 0.752678649695706 0.322296777026606 0.752678649695706
Calml4 ENSMUSG00000032246 0.657959394261783 0.883732196981301 0.532500763375392 0.883732196981301 0.883732196981301 0.883732196981301
Pde3a ENSMUSG00000041741 0.481386816722574 0.987393284158312 0.865193327753376 0.987393284158312 0.987393284158312 0.987393284158312
Clca6 ENSMUSG00000068547 0.184705064957882 0.554115194873645 0.750230108446751 0.750230108446751 0.379202474081209 0.568803711121813
AI747448 ENSMUSG00000074195 0.196945993181396 0.196945993181396 0.187623248465921 0.196945993181396 0.155069463443058 0.196945993181396

Fat digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Npc1l1 ENSMUSG00000020447 0.89949128307052 0.89949128307052 0.80972614436265 0.89949128307052 0.834294821690896 0.89949128307052
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Fabp2 ENSMUSG00000023057 0.898712284009231 0.898712284009231 0.398453482917805 0.597680224376708 0.0505201369343024 0.151560410802907
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Got2 ENSMUSG00000031672 0.260499903899206 0.390749855848809 0.0374574057899824 0.112372217369947 0.454800218425187 0.454800218425187
Ppap2c ENSMUSG00000052151 0.455290201122185 0.666978670869125 0.303936474764992 0.666978670869125 0.666978670869125 0.666978670869125
Mogat2 ENSMUSG00000052396 0.627771507062674 0.627771507062674 0.155748554566206 0.467245663698618 0.345327788768269 0.517991683152404

Parathyroid hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.102299592256669 0.153449388385003 0.00731057615207895 0.0219317284562369 0.707640614235423 0.707640614235423
Vdr ENSMUSG00000022479 0.993679418704703 0.993679418704703 0.914875070162745 0.993679418704703 0.549921416892069 0.993679418704703
Adcy6 ENSMUSG00000022994 0.076687927976775 0.230063783930325 0.19522296530981 0.292834447964714 0.752067769804379 0.752067769804379
Cdkn1a ENSMUSG00000023067 0.00953777499198078 0.0286133249759424 0.170440615742981 0.255660923614472 0.890070458203683 0.890070458203683
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Creb3l1 ENSMUSG00000027230 0.996850428855449 0.996850428855449 0.846567373929356 0.996850428855449 0.710447530185077 0.996850428855449
Pld1 ENSMUSG00000027695 0.616027987400436 0.918270497702046 0.918270497702046 0.918270497702046 0.233677903782894 0.701033711348682
Creb3l4 ENSMUSG00000027938 0.332525214759392 0.579673753109694 0.902593630950006 0.902593630950006 0.386449168739796 0.579673753109694
Slc34a2 ENSMUSG00000029188 0.463545808152237 0.899397094493345 0.899397094493345 0.899397094493345 0.811062715960212 0.899397094493345
Gna11 ENSMUSG00000034781 0.591279425426427 0.591279425426427 0.298384773042249 0.591279425426427 0.540474699135872 0.591279425426427
Creb3l2 ENSMUSG00000038648 0.448159771898262 0.641284171049983 0.0602976278928109 0.180892883678433 0.641284171049983 0.641284171049983
Mmp13 ENSMUSG00000050578 0.955698086958838 0.955698086958838 0.565632489538645 0.955698086958838 0.822064076206058 0.955698086958838
Bglap3 ENSMUSG00000074489 0.424532693804287 0.69576749313483 0.681203918783224 0.69576749313483 0.69576749313483 0.69576749313483

Histidine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aspa ENSMUSG00000020774 0.946510409134041 0.946510409134041 0.583066195958908 0.928249183025496 0.618832788683664 0.928249183025496
Cndp2 ENSMUSG00000024644 0.846642053526538 0.846642053526538 0.436332591839893 0.654498887759839 0.427054766727121 0.654498887759839
Maoa ENSMUSG00000025037 0.943358186549532 0.943358186549532 0.512073520332203 0.943358186549532 0.937072719959207 0.943358186549532
Aoc1 ENSMUSG00000029811 0.692750079162274 0.858193949287853 0.858193949287853 0.858193949287853 0.719945683390129 0.858193949287853
Aldh1b1 ENSMUSG00000035561 0.326676432587271 0.481819208398872 0.281881712659348 0.481819208398872 0.481819208398872 0.481819208398872
Cndp1 ENSMUSG00000056162 0.914699295505607 0.977702702684528 0.427643346373822 0.977702702684528 0.977702702684528 0.977702702684528

Tight junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Marveld3 ENSMUSG00000001672 0.531775059991694 0.71913629684942 0.282143882867587 0.71913629684942 0.71913629684942 0.71913629684942
Cldn15 ENSMUSG00000001739 0.868191943526124 0.868191943526124 0.348525354836619 0.868191943526124 0.865122064801421 0.868191943526124
Cldn7 ENSMUSG00000018569 0.648648755132817 0.731200983154223 0.127656983160222 0.382970949480665 0.731200983154223 0.731200983154223
Myh11 ENSMUSG00000018830 0.837252215080362 0.837252215080362 0.0713241889061641 0.213972566718492 0.499114637014626 0.748671955521939
Ocln ENSMUSG00000021638 0.710414567200792 0.809682295194204 0.809682295194204 0.809682295194204 0.610410176959505 0.809682295194204
Tjp2 ENSMUSG00000024812 0.666957236284153 0.719439191491012 0.376023061979478 0.719439191491012 0.719439191491012 0.719439191491012
Epb4.1l4b ENSMUSG00000028434 0.764199114237209 0.949653172878036 0.88390470336562 0.949653172878036 0.949653172878036 0.949653172878036
Myh14 ENSMUSG00000030739 0.149150471188473 0.299445112855568 0.199630075237046 0.299445112855568 0.658361485539787 0.658361485539787
Rdx ENSMUSG00000032050 0.930796465059262 0.930796465059262 0.246331444276094 0.738994332828281 0.564212085887152 0.846318128830728
Tjp3 ENSMUSG00000034917 0.618642024009941 0.97155866910672 0.84301749065435 0.97155866910672 0.97155866910672 0.97155866910672
Cftr ENSMUSG00000041301 0.640358515384076 0.96143303255907 0.96143303255907 0.96143303255907 0.883886726946972 0.96143303255907
Pard6b ENSMUSG00000044641 0.540342955478868 0.886965568027449 0.849708007584369 0.886965568027449 0.886965568027449 0.886965568027449
Rap2c ENSMUSG00000050029 0.809704796960407 0.849704490357394 0.376002218134932 0.849704490357394 0.849704490357394 0.849704490357394
Cldn23 ENSMUSG00000055976 0.486678603367371 0.778317001332864 0.778317001332864 0.778317001332864 0.526322907746402 0.778317001332864
Erbb2 ENSMUSG00000062312 0.180737332874653 0.54221199862396 0.504082681618086 0.678191607132893 0.678191607132893 0.678191607132893
Myl9 ENSMUSG00000067818 0.716480110415933 0.716480110415933 0.352942038663996 0.63374744862657 0.42249829908438 0.63374744862657
Cgn ENSMUSG00000068876 0.719331444914215 0.858943585809034 0.858943585809034 0.858943585809034 0.669734026070867 0.858943585809034

Glycerophospholipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Agpat3 ENSMUSG00000001211 0.731192092416326 0.731192092416326 0.106449390102905 0.319348170308714 0.230363270220595 0.345544905330892
Ptdss1 ENSMUSG00000021518 0.877656701788645 0.877656701788645 0.0405081128048405 0.121524338414522 0.661030660177479 0.877656701788645
Gpcpd1 ENSMUSG00000027346 0.641232019715152 0.912001036518114 0.912001036518114 0.912001036518114 0.865211137034211 0.912001036518114
Lpin3 ENSMUSG00000027412 0.350877233309094 0.526315849963642 0.800516748498999 0.800516748498999 0.276725908369913 0.526315849963642
Pld1 ENSMUSG00000027695 0.616027987400436 0.918270497702046 0.918270497702046 0.918270497702046 0.233677903782894 0.701033711348682
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Plb1 ENSMUSG00000029134 0.519954693773021 0.779932040659531 0.952980447169958 0.952980447169958 0.363005787285086 0.779932040659531
Agpat9 ENSMUSG00000029314 0.0856777155669593 0.257033146700878 0.618686808543379 0.785289842664283 0.785289842664283 0.785289842664283
Pla2g4c ENSMUSG00000033847 0.230250324084723 0.404422750661083 0.303860573015806 0.404422750661083 0.404422750661083 0.404422750661083
Mboat1 ENSMUSG00000038732 0.767161864604521 0.767161864604521 0.646812478218905 0.767161864604521 0.352627939276744 0.767161864604521
Ppap2c ENSMUSG00000052151 0.455290201122185 0.666978670869125 0.303936474764992 0.666978670869125 0.666978670869125 0.666978670869125
Lclat1 ENSMUSG00000054469 0.200983748863478 0.602951246590435 0.80973518982499 0.80973518982499 0.621591708076235 0.80973518982499

Vascular smooth muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.102299592256669 0.153449388385003 0.00731057615207895 0.0219317284562369 0.707640614235423 0.707640614235423
Myh11 ENSMUSG00000018830 0.837252215080362 0.837252215080362 0.0713241889061641 0.213972566718492 0.499114637014626 0.748671955521939
Kcnmb1 ENSMUSG00000020155 0.958937147145223 0.958937147145223 0.151480444467611 0.454441333402832 0.460712200653396 0.691068300980094
Edn1 ENSMUSG00000021367 0.551461145887251 0.551461145887251 0.164974271443126 0.247461407164689 0.146191318940917 0.247461407164689
Adcy6 ENSMUSG00000022994 0.076687927976775 0.230063783930325 0.19522296530981 0.292834447964714 0.752067769804379 0.752067769804379
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Edn3 ENSMUSG00000027524 0.486937463497489 0.933949137826282 0.661224422465519 0.933949137826282 0.933949137826282 0.933949137826282
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Myh14 ENSMUSG00000030739 0.149150471188473 0.299445112855568 0.199630075237046 0.299445112855568 0.658361485539787 0.658361485539787
Calml4 ENSMUSG00000032246 0.657959394261783 0.883732196981301 0.532500763375392 0.883732196981301 0.883732196981301 0.883732196981301
Pla2g4c ENSMUSG00000033847 0.230250324084723 0.404422750661083 0.303860573015806 0.404422750661083 0.404422750661083 0.404422750661083
Gna11 ENSMUSG00000034781 0.591279425426427 0.591279425426427 0.298384773042249 0.591279425426427 0.540474699135872 0.591279425426427
Acta2 ENSMUSG00000035783 0.987405276262937 0.987405276262937 0.137333599968668 0.412000799906005 0.434068340656254 0.65110251098438
Actg2 ENSMUSG00000059430 0.381271927764254 0.571907891646381 0.208160015232139 0.571907891646381 0.810697827296727 0.810697827296727
Myl9 ENSMUSG00000067818 0.716480110415933 0.716480110415933 0.352942038663996 0.63374744862657 0.42249829908438 0.63374744862657

Pancreatic secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc26a3 ENSMUSG00000001225 0.57469303476021 0.862039552140315 0.983929188570735 0.983929188570735 0.2534310281605 0.7602930844815
Kcnq1 ENSMUSG00000009545 0.964926596959531 0.964926596959531 0.467612567243953 0.758003492250036 0.505335661500024 0.758003492250036
Rab3d ENSMUSG00000019066 0.32885359034066 0.71353753041947 0.635669636361158 0.71353753041947 0.71353753041947 0.71353753041947
Adcy6 ENSMUSG00000022994 0.076687927976775 0.230063783930325 0.19522296530981 0.292834447964714 0.752067769804379 0.752067769804379
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Clca3 ENSMUSG00000028255 0.0620660984862553 0.186198295458766 0.565160266906818 0.576720033453063 0.576720033453063 0.576720033453063
Clca2 ENSMUSG00000028262 0.717349003668636 0.752678649695706 0.752678649695706 0.752678649695706 0.322296777026606 0.752678649695706
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Atp1a1 ENSMUSG00000033161 0.809730083674155 0.840467268521411 0.388958929735072 0.840467268521411 0.840467268521411 0.840467268521411
Cftr ENSMUSG00000041301 0.640358515384076 0.96143303255907 0.96143303255907 0.96143303255907 0.883886726946972 0.96143303255907
Clca6 ENSMUSG00000068547 0.184705064957882 0.554115194873645 0.750230108446751 0.750230108446751 0.379202474081209 0.568803711121813
AI747448 ENSMUSG00000074195 0.196945993181396 0.196945993181396 0.187623248465921 0.196945993181396 0.155069463443058 0.196945993181396

TGF-beta signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp8b ENSMUSG00000002384 0.875407874396952 0.938741040724223 0.851332286243104 0.938741040724223 0.938741040724223 0.938741040724223
Bmp4 ENSMUSG00000021835 0.23362222747644 0.537828573463316 0.537828573463316 0.537828573463316 0.380303168670458 0.537828573463316
Bambi ENSMUSG00000024232 0.86521473084879 0.924533065562506 0.924533065562506 0.924533065562506 0.395491003609986 0.924533065562506
Smad4 ENSMUSG00000024515 0.977961488371365 0.977961488371365 0.535133582690942 0.977961488371365 0.746115593655121 0.977961488371365
Pitx2 ENSMUSG00000028023 0.683794953850007 0.764689522167573 0.764689522167573 0.764689522167573 0.581070902920299 0.764689522167573
Bmp5 ENSMUSG00000032179 0.828071633629638 0.893251687426391 0.868303082271513 0.893251687426391 0.893251687426391 0.893251687426391
Bmp8a ENSMUSG00000032726 0.980801329698095 0.993454658457318 0.993454658457318 0.993454658457318 0.575602018905517 0.993454658457318
Smad6 ENSMUSG00000036867 0.108257397242174 0.324772191726521 0.311369047820782 0.467053571731173 0.698024590004291 0.698024590004291
Id1 ENSMUSG00000042745 0.604916005813923 0.604916005813923 0.281927926042772 0.490193686133157 0.326795790755438 0.490193686133157
Cdkn2b ENSMUSG00000073802 0.921367803242588 0.921367803242588 0.0731309009894443 0.219392702968333 0.532424622964415 0.798636934446622
Grem1 ENSMUSG00000074934 0.965125456727499 0.965125456727499 0.774379515773799 0.965125456727499 0.747306433058835 0.965125456727499

Adherens junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Yes1 ENSMUSG00000014932 0.734226921573868 0.955936630965391 0.37377666432107 0.955936630965391 0.955936630965391 0.955936630965391
Pvrl3 ENSMUSG00000022656 0.698867805561052 0.87145141855491 0.87145141855491 0.87145141855491 0.71944180253573 0.87145141855491
Smad4 ENSMUSG00000024515 0.977961488371365 0.977961488371365 0.535133582690942 0.977961488371365 0.746115593655121 0.977961488371365
Tcf7l2 ENSMUSG00000024985 0.737085300611517 0.940211495257432 0.940211495257432 0.940211495257432 0.818785324176866 0.940211495257432
Farp2 ENSMUSG00000034066 0.927654816734411 1 0.209137045160925 0.627411135482774 1 1
Ctnnd1 ENSMUSG00000034101 0.890106633204879 0.890106633204879 0.0947306902234862 0.284192070670459 0.672559498007883 0.890106633204879
Ctnna1 ENSMUSG00000037815 0.610510184662866 0.610510184662866 0.153900395921686 0.461701187765059 0.558920555230168 0.610510184662866
Erbb2 ENSMUSG00000062312 0.180737332874653 0.54221199862396 0.504082681618086 0.678191607132893 0.678191607132893 0.678191607132893
Csnk2a1 ENSMUSG00000074698 0.210971115955039 0.632913347865117 0.687065767635213 0.981100294205187 0.981100294205187 0.981100294205187

Vitamin digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcn2 ENSMUSG00000020432 0.681389096920327 0.681389096920327 0.215393022910959 0.646179068732878 0.519611323504592 0.681389096920327
Cubn ENSMUSG00000026726 0.837188761918865 0.852349564796451 0.852349564796451 0.852349564796451 0.757604171592282 0.852349564796451
Slc52a3 ENSMUSG00000027463 0.367527119010627 0.498931522676465 0.278120137312538 0.498931522676465 0.498931522676465 0.498931522676465
Plb1 ENSMUSG00000029134 0.519954693773021 0.779932040659531 0.952980447169958 0.952980447169958 0.363005787285086 0.779932040659531
Rbp2 ENSMUSG00000032454 0.953679405317952 0.953679405317952 0.183402868282337 0.55020860484701 0.633138708694006 0.94970806304101

Carbohydrate digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a1 ENSMUSG00000011034 0.88791075718043 0.888264024504141 0.746563448002747 0.888264024504141 0.888264024504141 0.888264024504141
Hkdc1 ENSMUSG00000020080 0.971461542987442 0.971475336205523 0.971475336205523 0.971475336205523 0.647653438592168 0.971475336205523
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Lct ENSMUSG00000026354 0.940901610906142 0.940901610906142 0.712662196408685 0.940901610906142 0.710720986002554 0.940901610906142
Sis ENSMUSG00000027790 0.427897360197622 0.465382249983061 0.465382249983061 0.465382249983061 0.224766927643762 0.465382249983061
Slc2a5 ENSMUSG00000028976 0.0577403727042465 0.17322111811274 0.585687397665491 0.585687397665491 0.259285339567866 0.388928009351799
Atp1a1 ENSMUSG00000033161 0.809730083674155 0.840467268521411 0.388958929735072 0.840467268521411 0.840467268521411 0.840467268521411

Alpha-defensins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Antimicrobial peptides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Clu ENSMUSG00000022037 0.701750192839715 0.701750192839715 0.294507543732328 0.701750192839715 0.540199081979916 0.701750192839715
Reg3g ENSMUSG00000030017 0.0409710371783857 0.0614565557675786 0.0143013634513591 0.0429040903540774 0.406067957770254 0.406067957770254
Pglyrp1 ENSMUSG00000030413 0.43836459252132 0.725877141819428 0.483918094546285 0.725877141819428 0.924412399469271 0.924412399469271
Itln1 ENSMUSG00000038209 0.116344515822276 0.349033547466829 0.805371434501049 0.805371434501049 0.419308881122581 0.628963321683871
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Reg3b ENSMUSG00000071356 0.0419462461212823 0.0629193691819234 0.00512137941775784 0.0153641382532735 0.896122674026714 0.896122674026714
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Defensins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Transport of small molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Car4 ENSMUSG00000000805 0.868341265495093 0.868341265495093 0.75816782586753 0.868341265495093 0.666960278638366 0.868341265495093
Slc7a7 ENSMUSG00000000958 0.174420391969767 0.261630587954651 0.303467860454927 0.303467860454927 0.12368397467234 0.261630587954651
Slc13a2 ENSMUSG00000001095 0.519348297401043 0.740849999654862 0.609784187578423 0.740849999654862 0.740849999654862 0.740849999654862
Slc26a3 ENSMUSG00000001225 0.57469303476021 0.862039552140315 0.983929188570735 0.983929188570735 0.2534310281605 0.7602930844815
Slc44a4 ENSMUSG00000007034 0.397900241125543 0.880075150078653 0.880075150078653 0.880075150078653 0.665572342615447 0.880075150078653
Mcu ENSMUSG00000009647 0.566929882017194 0.903347710135193 0.602231806756795 0.903347710135193 0.968519313290455 0.968519313290455
Slc12a4 ENSMUSG00000017765 0.34680608760272 0.499303265789525 0.0417630564290916 0.125289169287275 0.499303265789525 0.499303265789525
Slc22a5 ENSMUSG00000018900 0.243198009736123 0.548068352941349 0.580399935855718 0.580399935855718 0.3653789019609 0.548068352941349
Slc5a8 ENSMUSG00000020062 0.536190647912096 0.536190647912096 0.504485915253185 0.536190647912096 0.488441175570384 0.536190647912096
Slc28a3 ENSMUSG00000021553 0.810452999656633 0.810452999656633 0.79457590279049 0.810452999656633 0.481419872056541 0.810452999656633
Slc6a19 ENSMUSG00000021565 1 1 0.582902829398259 0.874354244097389 0.486780613861072 0.874354244097389
Psmc6 ENSMUSG00000021832 0.00325988625821721 0.00709575168938974 0.00473050112625983 0.00709575168938974 0.643917003571691 0.643917003571691
Micu2 ENSMUSG00000021973 0.74617096739568 0.74617096739568 0.384638460187937 0.74617096739568 0.684271061305973 0.74617096739568
Smdt1 ENSMUSG00000022452 0.0021467697184223 0.00322015457763345 3.91958882772132e-05 0.00011758766483164 0.384395292917059 0.384395292917059
Slc26a6 ENSMUSG00000023259 0.0427744564776817 0.128323369433045 0.104504514943076 0.156756772414614 0.532449303840237 0.532449303840237
Afg3l2 ENSMUSG00000024527 0.993700732818188 0.993700732818188 0.0110779011301941 0.0332337033905824 0.354844188650442 0.532266282975663
Pcsk5 ENSMUSG00000024713 0.868345460709282 0.921405388133253 0.921405388133253 0.921405388133253 0.785356985722601 0.921405388133253
Trpm6 ENSMUSG00000024727 0.961603977289231 0.961603977289231 0.936520548644379 0.961603977289231 0.448300978809613 0.961603977289231
Slc15a1 ENSMUSG00000025557 0.701230330178935 0.99003672266318 0.99003672266318 0.99003672266318 0.941460073281463 0.99003672266318
Slc28a1 ENSMUSG00000025726 0.525293804915579 0.550950006236463 0.0896053569833896 0.268816070950169 0.550950006236463 0.550950006236463
Slc9a2 ENSMUSG00000026062 0.918260729530517 0.918260729530517 0.72826886686269 0.918260729530517 0.785340030441985 0.918260729530517
Slc2a10 ENSMUSG00000027661 0.75208645087951 0.75208645087951 0.687165928034635 0.75208645087951 0.406493832073409 0.75208645087951
Clca3 ENSMUSG00000028255 0.0620660984862553 0.186198295458766 0.565160266906818 0.576720033453063 0.576720033453063 0.576720033453063
Slc34a2 ENSMUSG00000029188 0.463545808152237 0.899397094493345 0.899397094493345 0.899397094493345 0.811062715960212 0.899397094493345
Slc13a1 ENSMUSG00000029700 0.797075153745813 0.983483493671718 0.530358341677086 0.983483493671718 0.983483493671718 0.983483493671718
Slc7a9 ENSMUSG00000030492 0.960748588186069 0.960748588186069 0.498264459931539 0.747396689897308 0.31636548300845 0.747396689897308
Slc5a11 ENSMUSG00000030769 0.974759619346305 0.974759619346305 0.730976256477519 0.974759619346305 0.733530178543178 0.974759619346305
Ano1 ENSMUSG00000031075 0.404269907528547 0.404269907528547 0.216568664098743 0.404269907528547 0.30916398014399 0.404269907528547
Heph ENSMUSG00000031209 0.883802096989625 0.977960187040556 0.977960187040556 0.977960187040556 0.390801752810548 0.977960187040556
Ldlr ENSMUSG00000032193 0.441070441028549 0.800578163640214 0.794483882303149 0.800578163640214 0.800578163640214 0.800578163640214
Atp1a1 ENSMUSG00000033161 0.809730083674155 0.840467268521411 0.388958929735072 0.840467268521411 0.840467268521411 0.840467268521411
Ano7 ENSMUSG00000034107 0.897511629299418 0.897511629299418 0.848225031102841 0.897511629299418 0.581414402545207 0.897511629299418
Atp2c2 ENSMUSG00000034112 0.480613683860206 0.569292330258753 0.569292330258753 0.569292330258753 0.510365921036978 0.569292330258753
Slc26a2 ENSMUSG00000034320 0.90247265456362 0.977924570676233 0.971666140526556 0.977924570676233 0.977924570676233 0.977924570676233
Slc9a3 ENSMUSG00000036123 0.477231542692887 0.71584731403933 0.966584200819459 0.966584200819459 0.377614390638735 0.71584731403933
Gng12 ENSMUSG00000036402 0.486932396619674 0.81280345050574 0.81280345050574 0.81280345050574 0.779300312905748 0.81280345050574
Slc20a2 ENSMUSG00000037656 0.532627139143593 0.532627139143593 0.126088110930639 0.378264332791916 0.292867443801955 0.439301165702933
Ano10 ENSMUSG00000037949 0.10639559076107 0.319186772283211 0.403972982497209 0.605959473745814 0.840303045729677 0.840303045729677
Atp6v0a2 ENSMUSG00000038023 0.90260447954445 0.90260447954445 0.103952826131909 0.311858478395727 0.788375339111343 0.90260447954445
Trpm4 ENSMUSG00000038260 0.105704178235311 0.215621527137519 0.143747684758346 0.215621527137519 0.484395094921789 0.484395094921789
Atp8b1 ENSMUSG00000039529 0.553546034535322 0.553546034535322 0.519670878832056 0.553546034535322 0.448049905828484 0.553546034535322
Abcb1a ENSMUSG00000040584 0.828072484840679 0.877615252211565 0.788371393110564 0.877615252211565 0.877615252211565 0.877615252211565
Cftr ENSMUSG00000041301 0.640358515384076 0.96143303255907 0.96143303255907 0.96143303255907 0.883886726946972 0.96143303255907
Aqp11 ENSMUSG00000042797 0.887020562094905 0.887020562094905 0.701795932770667 0.887020562094905 0.693026412418828 0.887020562094905
Ano9 ENSMUSG00000054662 0.90160877066452 0.90160877066452 0.593088650300145 0.889632975450218 0.503566709160204 0.889632975450218
Atp10b ENSMUSG00000055415 0.487108271153202 0.674730948553226 0.674730948553226 0.674730948553226 0.271447063334994 0.674730948553226
Fxyd3 ENSMUSG00000057092 0.347429562162492 0.521144343243737 0.996805862725639 0.996805862725639 0.267496692423806 0.521144343243737
Slc39a4 ENSMUSG00000063354 0.74387061428507 0.880328935168269 0.880328935168269 0.880328935168269 0.873303209257354 0.880328935168269
Nipal1 ENSMUSG00000067219 0.690993069966361 0.806741516019489 0.337722745005358 0.806741516019489 0.806741516019489 0.806741516019489
AI747448 ENSMUSG00000074195 0.196945993181396 0.196945993181396 0.187623248465921 0.196945993181396 0.155069463443058 0.196945993181396
Eif2s2 ENSMUSG00000074656 0.0154429596389953 0.023164439458493 0.0139200754038277 0.023164439458493 0.852639395270761 0.852639395270761

Neutrophil degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Jup ENSMUSG00000001552 0.190060250508939 0.295328587106757 0.196885724737838 0.295328587106757 0.943368515910083 0.943368515910083
Aprt ENSMUSG00000006589 0.164477209052713 0.49343162715814 0.3653789019609 0.548068352941349 0.574970666443981 0.574970666443981
Neu1 ENSMUSG00000007038 0.61879264316566 0.984253153889948 0.684251668796809 0.984253153889948 0.984253153889948 0.984253153889948
Rab3d ENSMUSG00000019066 0.32885359034066 0.71353753041947 0.635669636361158 0.71353753041947 0.71353753041947 0.71353753041947
Frk ENSMUSG00000019779 0.671932093422096 0.709469056335535 0.709469056335535 0.709469056335535 0.425982239702509 0.709469056335535
Fuca2 ENSMUSG00000019810 0.80974485912318 0.880786195583329 0.68719962444768 0.880786195583329 0.880786195583329 0.880786195583329
Psen1 ENSMUSG00000019969 0.843557864240999 0.843557864240999 0.336762369103744 0.83838531508915 0.558923543392767 0.83838531508915
Olfm4 ENSMUSG00000022026 0.772419498604999 0.772419498604999 0.662912711791742 0.772419498604999 0.671786680755697 0.772419498604999
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Igf2r ENSMUSG00000023830 0.815577865781973 0.815577865781973 0.124901000532006 0.374703001596017 0.582427318826931 0.815577865781973
Cant1 ENSMUSG00000025575 0.402172302162049 0.603258453243073 0.393362699237923 0.603258453243073 0.693008868680827 0.693008868680827
Slc2a5 ENSMUSG00000028976 0.0577403727042465 0.17322111811274 0.585687397665491 0.585687397665491 0.259285339567866 0.388928009351799
Pgm1 ENSMUSG00000029171 0.219923142229254 0.659769426687761 0.716357308829155 0.716357308829155 0.457508869905054 0.686263304857581
Pglyrp1 ENSMUSG00000030413 0.43836459252132 0.725877141819428 0.483918094546285 0.725877141819428 0.924412399469271 0.924412399469271
Lamp1 ENSMUSG00000031447 0.800558803056353 0.94650303755014 0.129076966532205 0.387230899596615 0.94650303755014 0.94650303755014
Anxa2 ENSMUSG00000032231 0.877666366394871 0.90888328285808 0.90888328285808 0.90888328285808 0.713522481070673 0.90888328285808
Acpp ENSMUSG00000032561 0.88302082897831 0.889505410577042 0.567586472036163 0.889505410577042 0.889505410577042 0.889505410577042
Chrnb4 ENSMUSG00000035200 0.903808421064255 0.945327255137211 0.482170128392123 0.945327255137211 0.945327255137211 0.945327255137211
Siglec5 ENSMUSG00000039013 0.281667687810849 0.422501531716273 0.813687118346099 0.813687118346099 0.144024533382086 0.422501531716273
Anpep ENSMUSG00000039062 0.760984716137745 0.760984716137745 0.326448666750582 0.760984716137745 0.574784252911429 0.760984716137745
Cystm1 ENSMUSG00000046727 0.50950802289795 0.527432504646767 0.424811024561713 0.527432504646767 0.527432504646767 0.527432504646767
Bri3 ENSMUSG00000047843 0.0136365772296199 0.0204548658444299 0.0100983433856543 0.0204548658444299 0.489247588921945 0.489247588921945
Mlec ENSMUSG00000048578 0.669798273512639 0.971661804297774 0.280309566885597 0.840928700656791 0.971661804297774 0.971661804297774
Rap2c ENSMUSG00000050029 0.809704796960407 0.849704490357394 0.376002218134932 0.849704490357394 0.849704490357394 0.849704490357394
Dsp ENSMUSG00000054889 0.671394923337438 0.952593019034496 0.952593019034496 0.952593019034496 0.355287894228245 0.952593019034496
AY761184 ENSMUSG00000058618 0.498958962719943 0.748438444079915 0.262095468843076 0.748438444079915 0.895332923752533 0.895332923752533
Gm14851 ENSMUSG00000061958 0.86765521982901 0.86765521982901 0.0243735571519527 0.0731206714558582 0.729913371766153 0.86765521982901
Defa24 ENSMUSG00000064213 0.175255434421463 0.262883151632194 0.0194975433276139 0.0584926299828416 0.356187534614939 0.356187534614939
Gm14850 ENSMUSG00000065956 0.6098927010965 0.928090910667242 0.955711458086419 0.955711458086419 0.618727273778161 0.928090910667242
H2-Bl ENSMUSG00000073406 0.172568926098625 0.517706778295875 0.797425585018949 0.911924479323142 0.911924479323142 0.911924479323142
Defa3 ENSMUSG00000074440 0.581949006448418 0.872923509672627 0.217952030854142 0.653856092562425 0.91719039200699 0.91719039200699
Gm15284 ENSMUSG00000074444 0.789056945910488 0.901529722345995 0.242258520525506 0.726775561576519 0.901529722345995 0.901529722345995
Defa23 ENSMUSG00000074446 0.199879104342438 0.199879104342438 0.0451060186493737 0.135318055948121 0.163579869689209 0.199879104342438
Defa21 ENSMUSG00000074447 0.614444899901737 0.921667349852605 0.959040177069419 0.959040177069419 0.288332645475452 0.864997936426354
Gm7849 ENSMUSG00000079114 0.742566060613537 0.839654147489455 0.839654147489455 0.839654147489455 0.3718818630282 0.839654147489455
Gm15293 ENSMUSG00000079116 0.867901105451382 0.897291584258936 0.475768418088769 0.897291584258936 0.897291584258936 0.897291584258936
Gm11127 ENSMUSG00000079492 0.748237529935523 0.871147298578738 0.871147298578738 0.871147298578738 0.848916522939892 0.871147298578738
H2-Q1 ENSMUSG00000079507 0.472665306610815 0.929455827775484 0.825865765097784 0.929455827775484 0.929455827775484 0.929455827775484
H2-Q2 ENSMUSG00000091705 0.861634473623245 0.864897370496507 0.864897370496507 0.864897370496507 0.827867109539421 0.864897370496507
Dynlt1a ENSMUSG00000092074 0.731254773664821 0.88077709190345 0.88077709190345 0.88077709190345 0.81280509174816 0.88077709190345
Gm15308 ENSMUSG00000094818 0.120685642751421 0.362056928254263 0.899312483118638 0.899312483118638 0.552181965583242 0.828272948374863
Defa20 ENSMUSG00000095066 0.407596210937462 0.611394316406193 0.14276188995616 0.42828566986848 0.871109120868058 0.871109120868058

Digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Guca2a ENSMUSG00000023247 0.673067195217231 0.673067195217231 0.485483726506783 0.673067195217231 0.361757564462248 0.673067195217231
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Lct ENSMUSG00000026354 0.940901610906142 0.940901610906142 0.712662196408685 0.940901610906142 0.710720986002554 0.940901610906142
Sis ENSMUSG00000027790 0.427897360197622 0.465382249983061 0.465382249983061 0.465382249983061 0.224766927643762 0.465382249983061
Slc2a5 ENSMUSG00000028976 0.0577403727042465 0.17322111811274 0.585687397665491 0.585687397665491 0.259285339567866 0.388928009351799
Guca2b ENSMUSG00000032978 0.623313086026837 0.879986003770997 0.879986003770997 0.879986003770997 0.783654385068812 0.879986003770997
Gucy2c ENSMUSG00000042638 0.946220990503486 0.946220990503486 0.676410510755997 0.946220990503486 0.744213808756341 0.946220990503486

O-linked glycosylation of mucins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Muc13 ENSMUSG00000022824 0.536148802500162 0.536148802500162 0.127016136054218 0.381048408162653 0.396537000576402 0.536148802500162
Galnt3 ENSMUSG00000026994 0.987400304476363 0.987400304476363 0.666853256647925 0.987400304476363 0.454804061333491 0.987400304476363
Galnt7 ENSMUSG00000031608 0.169335132385826 0.508005397157478 0.767119791588071 0.98110373090371 0.98110373090371 0.98110373090371
B3gnt3 ENSMUSG00000031803 0.890105010732863 0.890105010732863 0.142482916164533 0.427448748493599 0.455018379120772 0.682527568681158
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Galnt6 ENSMUSG00000037280 0.734243232682629 0.734243232682629 0.602195408694262 0.734243232682629 0.481949492250282 0.734243232682629
St6galnac2 ENSMUSG00000057286 0.779284082219453 0.779284082219453 0.280291718596716 0.623455032437237 0.415636688291491 0.623455032437237
B3gnt6 ENSMUSG00000074004 0.977876207817531 0.977876207817531 0.827890587351799 0.977876207817531 0.600640521017228 0.977876207817531
B3gnt7 ENSMUSG00000079445 0.943158889193063 0.943158889193063 0.805902961947636 0.943158889193063 0.883323694259756 0.943158889193063
Gcnt4 ENSMUSG00000091387 0.981078221363129 0.981078221363129 0.930803750314257 0.981078221363129 0.886832830838805 0.981078221363129

SLC-mediated transmembrane transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc7a7 ENSMUSG00000000958 0.174420391969767 0.261630587954651 0.303467860454927 0.303467860454927 0.12368397467234 0.261630587954651
Slc13a2 ENSMUSG00000001095 0.519348297401043 0.740849999654862 0.609784187578423 0.740849999654862 0.740849999654862 0.740849999654862
Slc26a3 ENSMUSG00000001225 0.57469303476021 0.862039552140315 0.983929188570735 0.983929188570735 0.2534310281605 0.7602930844815
Slc44a4 ENSMUSG00000007034 0.397900241125543 0.880075150078653 0.880075150078653 0.880075150078653 0.665572342615447 0.880075150078653
Slc12a4 ENSMUSG00000017765 0.34680608760272 0.499303265789525 0.0417630564290916 0.125289169287275 0.499303265789525 0.499303265789525
Slc22a5 ENSMUSG00000018900 0.243198009736123 0.548068352941349 0.580399935855718 0.580399935855718 0.3653789019609 0.548068352941349
Slc5a8 ENSMUSG00000020062 0.536190647912096 0.536190647912096 0.504485915253185 0.536190647912096 0.488441175570384 0.536190647912096
Slc28a3 ENSMUSG00000021553 0.810452999656633 0.810452999656633 0.79457590279049 0.810452999656633 0.481419872056541 0.810452999656633
Slc6a19 ENSMUSG00000021565 1 1 0.582902829398259 0.874354244097389 0.486780613861072 0.874354244097389
Slc26a6 ENSMUSG00000023259 0.0427744564776817 0.128323369433045 0.104504514943076 0.156756772414614 0.532449303840237 0.532449303840237
Slc15a1 ENSMUSG00000025557 0.701230330178935 0.99003672266318 0.99003672266318 0.99003672266318 0.941460073281463 0.99003672266318
Slc28a1 ENSMUSG00000025726 0.525293804915579 0.550950006236463 0.0896053569833896 0.268816070950169 0.550950006236463 0.550950006236463
Slc9a2 ENSMUSG00000026062 0.918260729530517 0.918260729530517 0.72826886686269 0.918260729530517 0.785340030441985 0.918260729530517
Slc2a10 ENSMUSG00000027661 0.75208645087951 0.75208645087951 0.687165928034635 0.75208645087951 0.406493832073409 0.75208645087951
Slc34a2 ENSMUSG00000029188 0.463545808152237 0.899397094493345 0.899397094493345 0.899397094493345 0.811062715960212 0.899397094493345
Slc13a1 ENSMUSG00000029700 0.797075153745813 0.983483493671718 0.530358341677086 0.983483493671718 0.983483493671718 0.983483493671718
Slc7a9 ENSMUSG00000030492 0.960748588186069 0.960748588186069 0.498264459931539 0.747396689897308 0.31636548300845 0.747396689897308
Slc5a11 ENSMUSG00000030769 0.974759619346305 0.974759619346305 0.730976256477519 0.974759619346305 0.733530178543178 0.974759619346305
Heph ENSMUSG00000031209 0.883802096989625 0.977960187040556 0.977960187040556 0.977960187040556 0.390801752810548 0.977960187040556
Slc26a2 ENSMUSG00000034320 0.90247265456362 0.977924570676233 0.971666140526556 0.977924570676233 0.977924570676233 0.977924570676233
Slc9a3 ENSMUSG00000036123 0.477231542692887 0.71584731403933 0.966584200819459 0.966584200819459 0.377614390638735 0.71584731403933
Slc20a2 ENSMUSG00000037656 0.532627139143593 0.532627139143593 0.126088110930639 0.378264332791916 0.292867443801955 0.439301165702933
Slc39a4 ENSMUSG00000063354 0.74387061428507 0.880328935168269 0.880328935168269 0.880328935168269 0.873303209257354 0.880328935168269

Digestion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Guca2a ENSMUSG00000023247 0.673067195217231 0.673067195217231 0.485483726506783 0.673067195217231 0.361757564462248 0.673067195217231
Pnliprp2 ENSMUSG00000025091 0.731496163550833 0.731496163550833 0.233716364471426 0.350574546707138 0.202889877008018 0.350574546707138
Lct ENSMUSG00000026354 0.940901610906142 0.940901610906142 0.712662196408685 0.940901610906142 0.710720986002554 0.940901610906142
Sis ENSMUSG00000027790 0.427897360197622 0.465382249983061 0.465382249983061 0.465382249983061 0.224766927643762 0.465382249983061
Guca2b ENSMUSG00000032978 0.623313086026837 0.879986003770997 0.879986003770997 0.879986003770997 0.783654385068812 0.879986003770997
Gucy2c ENSMUSG00000042638 0.946220990503486 0.946220990503486 0.676410510755997 0.946220990503486 0.744213808756341 0.946220990503486

Synthesis of substrates in N-glycan biosythesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Neu1 ENSMUSG00000007038 0.61879264316566 0.984253153889948 0.684251668796809 0.984253153889948 0.984253153889948 0.984253153889948
Tsta3 ENSMUSG00000022570 0.0367365312689306 0.110209593806792 0.462501201214523 0.583063795513227 0.583063795513227 0.583063795513227
St6galnac6 ENSMUSG00000026811 0.740221592894354 0.933943501145503 0.42019228812206 0.933943501145503 0.933943501145503 0.933943501145503
Dolpp1 ENSMUSG00000026856 0.752136817819924 0.886949277587635 0.886949277587635 0.886949277587635 0.782180492597579 0.886949277587635
Gfpt1 ENSMUSG00000029992 0.322940567966185 0.921407679645115 0.921407679645115 0.921407679645115 0.755165907034892 0.921407679645115
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Gmds ENSMUSG00000038372 0.701723443319335 0.952780102682691 0.361186146827202 0.952780102682691 0.952780102682691 0.952780102682691
St3gal5 ENSMUSG00000056091 0.93080461359939 0.93080461359939 0.206712406396208 0.620137219188626 0.687170397241485 0.93080461359939
Pgm3 ENSMUSG00000056131 0.794438413901895 0.794438413901895 0.558892648149637 0.794438413901895 0.776219665474985 0.794438413901895
St6galnac2 ENSMUSG00000057286 0.779284082219453 0.779284082219453 0.280291718596716 0.623455032437237 0.415636688291491 0.623455032437237

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Car4 ENSMUSG00000000805 0.868341265495093 0.868341265495093 0.75816782586753 0.868341265495093 0.666960278638366 0.868341265495093
Agpat3 ENSMUSG00000001211 0.731192092416326 0.731192092416326 0.106449390102905 0.319348170308714 0.230363270220595 0.345544905330892
Ppard ENSMUSG00000002250 0.188654854685664 0.282982282028496 0.185835268240568 0.282982282028496 0.959070928738294 0.959070928738294
Sult2b1 ENSMUSG00000003271 0.585015429585781 0.833668450220394 0.833668450220394 0.833668450220394 0.584301579247104 0.833668450220394
Itpkc ENSMUSG00000003752 0.132122608287715 0.396367824863144 0.273206597295387 0.409809895943081 0.506970347759577 0.506970347759577
Plekha8 ENSMUSG00000005225 0.294543504189746 0.450113656693376 0.300075771128917 0.450113656693376 0.990548389211474 0.990548389211474
Ggt1 ENSMUSG00000006345 0.484322295578906 0.918226932301916 0.852764372242287 0.918226932301916 0.918226932301916 0.918226932301916
Aprt ENSMUSG00000006589 0.164477209052713 0.49343162715814 0.3653789019609 0.548068352941349 0.574970666443981 0.574970666443981
Slc44a4 ENSMUSG00000007034 0.397900241125543 0.880075150078653 0.880075150078653 0.880075150078653 0.665572342615447 0.880075150078653
Neu1 ENSMUSG00000007038 0.61879264316566 0.984253153889948 0.684251668796809 0.984253153889948 0.984253153889948 0.984253153889948
Plcd1 ENSMUSG00000010660 0.0581193783522371 0.174358135056711 0.572259016322503 0.572259016322503 0.395533324361179 0.572259016322503
Ada ENSMUSG00000017697 0.40651664223584 0.965825270082217 0.990544366083357 0.990544366083357 0.643883513388145 0.965825270082217
Slc22a5 ENSMUSG00000018900 0.243198009736123 0.548068352941349 0.580399935855718 0.580399935855718 0.3653789019609 0.548068352941349
Dpep1 ENSMUSG00000019278 0.940179350865115 0.981093106545494 0.981093106545494 0.981093106545494 0.918255443798909 0.981093106545494
Aoc3 ENSMUSG00000019326 0.680456846597119 0.990522279821747 0.660657868426263 0.990522279821747 0.990522279821747 0.990522279821747
Smpd2 ENSMUSG00000019822 0.0183912729291572 0.0551738187874714 0.779142223607204 0.87449186937348 0.87449186937348 0.87449186937348
Nudt4 ENSMUSG00000020029 0.883814328144533 0.883814328144533 0.194056682290376 0.582170046871128 0.716332152741747 0.883814328144533
Slc5a8 ENSMUSG00000020062 0.536190647912096 0.536190647912096 0.504485915253185 0.536190647912096 0.488441175570384 0.536190647912096
Ddc ENSMUSG00000020182 0.591245347109318 0.831233453001025 0.427081878005525 0.831233453001025 0.831233453001025 0.831233453001025
Txnrd1 ENSMUSG00000020250 0.99684840263851 0.99684840263851 0.100518791979212 0.301556375937636 0.710332358136141 0.99684840263851
Fabp6 ENSMUSG00000020405 0.815656370044859 0.918117516668444 0.00522670212475744 0.0156801063742723 0.918117516668444 0.918117516668444
Upp1 ENSMUSG00000020407 0.53438933974896 0.751958251909793 0.751958251909793 0.751958251909793 0.635021407721474 0.751958251909793
Tcn2 ENSMUSG00000020432 0.681389096920327 0.681389096920327 0.215393022910959 0.646179068732878 0.519611323504592 0.681389096920327
Aspa ENSMUSG00000020774 0.946510409134041 0.946510409134041 0.583066195958908 0.928249183025496 0.618832788683664 0.928249183025496
Sptlc2 ENSMUSG00000021036 0.262904682003909 0.767829662437442 0.511886441624961 0.767829662437442 0.776152833206285 0.776152833206285
Arg2 ENSMUSG00000021125 0.532564995330278 0.698702944257651 0.46234208571082 0.698702944257651 0.698702944257651 0.698702944257651
Degs2 ENSMUSG00000021263 0.724164730722854 0.739451628849382 0.739451628849382 0.739451628849382 0.546609578577222 0.739451628849382
Ptdss1 ENSMUSG00000021518 0.877656701788645 0.877656701788645 0.0405081128048405 0.121524338414522 0.661030660177479 0.877656701788645
Glrx ENSMUSG00000021591 0.496897462833213 0.745346194249819 0.0130683225732825 0.0392049677198475 0.797500172921171 0.797500172921171
Elovl7 ENSMUSG00000021696 0.6957322516322 0.946357994156981 0.74258336929697 0.946357994156981 0.946357994156981 0.946357994156981
Psmc6 ENSMUSG00000021832 0.00325988625821721 0.00709575168938974 0.00473050112625983 0.00709575168938974 0.643917003571691 0.643917003571691
Cryl1 ENSMUSG00000021947 0.624442662917326 0.791441740103188 0.791441740103188 0.791441740103188 0.630051756529549 0.791441740103188
Vdr ENSMUSG00000022479 0.993679418704703 0.993679418704703 0.914875070162745 0.993679418704703 0.549921416892069 0.993679418704703
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Pycrl ENSMUSG00000022571 0.382415151018369 0.818905364971026 0.818905364971026 0.818905364971026 0.613296570850605 0.818905364971026
Fabp2 ENSMUSG00000023057 0.898712284009231 0.898712284009231 0.398453482917805 0.597680224376708 0.0505201369343024 0.151560410802907
Serinc2 ENSMUSG00000023232 0.69883193626952 0.764188202519118 0.291017038406046 0.764188202519118 0.764188202519118 0.764188202519118
Me2 ENSMUSG00000024556 0.627235003668412 0.91513920805033 0.91513920805033 0.91513920805033 0.782324214781721 0.91513920805033
Cndp2 ENSMUSG00000024644 0.846642053526538 0.846642053526538 0.436332591839893 0.654498887759839 0.427054766727121 0.654498887759839
Rfk ENSMUSG00000024712 0.943360952543614 0.943360952543614 0.0288562081812464 0.0865686245437393 0.776263968195261 0.943360952543614
Asah2 ENSMUSG00000024887 0.981087628957424 0.981087628957424 0.769990243472496 0.981087628957424 0.678404091653036 0.981087628957424
Plcb3 ENSMUSG00000024960 0.324832065704447 0.48724809855667 0.0843449062908061 0.253034718872418 0.566829155896398 0.566829155896398
Aldh18a1 ENSMUSG00000025007 0.990547717285726 0.990547717285726 0.307566228065496 0.922698684196487 0.752035704634922 0.990547717285726
Maoa ENSMUSG00000025037 0.943358186549532 0.943358186549532 0.512073520332203 0.943358186549532 0.937072719959207 0.943358186549532
Gsto1 ENSMUSG00000025068 0.632662654199987 0.632662654199987 0.123060414533276 0.369181243599829 0.593768647994058 0.632662654199987
Pycr1 ENSMUSG00000025140 0.977958666479294 0.977958666479294 0.632800375855301 0.949200563782951 0.452864274515534 0.949200563782951
Entpd7 ENSMUSG00000025192 0.52473004317972 0.810579191428076 0.540386127618717 0.810579191428076 0.968511019385728 0.968511019385728
Pfkfb4 ENSMUSG00000025648 0.638470006168582 0.877658409866045 0.672700994389528 0.877658409866045 0.877658409866045 0.877658409866045
Aasdhppt ENSMUSG00000025894 0.229037299737388 0.687111899212164 0.8497329528996 0.8497329528996 0.72533646731679 0.8497329528996
Adhfe1 ENSMUSG00000025911 0.512066773531922 0.89013987195913 0.604983403713282 0.89013987195913 0.89013987195913 0.89013987195913
Bpnt1 ENSMUSG00000026617 0.821990260155696 0.821990260155696 0.443439463546384 0.821990260155696 0.776260465807766 0.821990260155696
St6galnac6 ENSMUSG00000026811 0.740221592894354 0.933943501145503 0.42019228812206 0.933943501145503 0.933943501145503 0.933943501145503
Ivd ENSMUSG00000027332 0.00851885708117468 0.025556571243524 0.350899246864757 0.352903319267405 0.352903319267405 0.352903319267405
Lpin3 ENSMUSG00000027412 0.350877233309094 0.526315849963642 0.800516748498999 0.800516748498999 0.276725908369913 0.526315849963642
Slc52a3 ENSMUSG00000027463 0.367527119010627 0.498931522676465 0.278120137312538 0.498931522676465 0.498931522676465 0.498931522676465
Car13 ENSMUSG00000027555 0.725133987085329 0.968485576703039 0.968485576703039 0.968485576703039 0.719102929403769 0.968485576703039
Acp6 ENSMUSG00000028093 0.955938842529787 0.955938842529787 0.417922550209206 0.955938842529787 0.794485564907848 0.955938842529787
Car9 ENSMUSG00000028463 0.83416222003248 0.921380859905091 0.469156993920399 0.921380859905091 0.921380859905091 0.921380859905091
Akr1a1 ENSMUSG00000028692 0.175669161597978 0.527007484793935 0.38028546057159 0.570428190857386 0.782294421562961 0.782294421562961
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Plb1 ENSMUSG00000029134 0.519954693773021 0.779932040659531 0.952980447169958 0.952980447169958 0.363005787285086 0.779932040659531
Pgm1 ENSMUSG00000029171 0.219923142229254 0.659769426687761 0.716357308829155 0.716357308829155 0.457508869905054 0.686263304857581
Sult1b1 ENSMUSG00000029269 0.437901285811627 0.59219996896207 0.59219996896207 0.59219996896207 0.473444000543037 0.59219996896207
Agpat9 ENSMUSG00000029314 0.0856777155669593 0.257033146700878 0.618686808543379 0.785289842664283 0.785289842664283 0.785289842664283
Tpk1 ENSMUSG00000029735 0.616036151017144 0.831193775685723 0.831193775685723 0.831193775685723 0.621562319800369 0.831193775685723
Cidec ENSMUSG00000030278 0.74061145499343 0.97429710344972 0.872036897524222 0.97429710344972 0.97429710344972 0.97429710344972
Acadsb ENSMUSG00000030861 0.76112479409503 0.76112479409503 0.388871781094042 0.76112479409503 0.758177245704243 0.76112479409503
Mtm1 ENSMUSG00000031337 0.718734043101403 0.718734043101403 0.373628407431785 0.718734043101403 0.539477560053959 0.718734043101403
Bmx ENSMUSG00000031377 0.740323292931886 0.740323292931886 0.525003308301008 0.740323292931886 0.617560037825014 0.740323292931886
Ido1 ENSMUSG00000031551 0.246899479807979 0.703634444422564 0.703634444422564 0.703634444422564 0.527028737621969 0.703634444422564
Got2 ENSMUSG00000031672 0.260499903899206 0.390749855848809 0.0374574057899824 0.112372217369947 0.454800218425187 0.454800218425187
B3gnt3 ENSMUSG00000031803 0.890105010732863 0.890105010732863 0.142482916164533 0.427448748493599 0.455018379120772 0.682527568681158
Cyb5b ENSMUSG00000031924 0.918262157684782 0.918262157684782 0.28189467050752 0.814413317724517 0.542942211816345 0.814413317724517
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Bckdhb ENSMUSG00000032263 0.262892472475128 0.788677417425383 0.535179883315182 0.802769824972773 0.890135020932439 0.890135020932439
Nt5e ENSMUSG00000032420 0.834298925036398 0.834298925036398 0.635313755157743 0.834298925036398 0.83108749140236 0.834298925036398
Rbp2 ENSMUSG00000032454 0.953679405317952 0.953679405317952 0.183402868282337 0.55020860484701 0.633138708694006 0.94970806304101
Pon2 ENSMUSG00000032667 0.761136930530304 0.996850839678697 0.996850839678697 0.996850839678697 0.785305522812458 0.996850839678697
Sgpp2 ENSMUSG00000032908 0.977792051611679 0.977792051611679 0.664091401167753 0.977792051611679 0.814818803342026 0.977792051611679
Pla2g4c ENSMUSG00000033847 0.230250324084723 0.404422750661083 0.303860573015806 0.404422750661083 0.404422750661083 0.404422750661083
Slc26a2 ENSMUSG00000034320 0.90247265456362 0.977924570676233 0.971666140526556 0.977924570676233 0.977924570676233 0.977924570676233
Nostrin ENSMUSG00000034738 0.0433385094668059 0.130015528400418 0.868248197684233 0.868248197684233 0.809563481296163 0.868248197684233
Gna11 ENSMUSG00000034781 0.591279425426427 0.591279425426427 0.298384773042249 0.591279425426427 0.540474699135872 0.591279425426427
Aldh1b1 ENSMUSG00000035561 0.326676432587271 0.481819208398872 0.281881712659348 0.481819208398872 0.481819208398872 0.481819208398872
Gng12 ENSMUSG00000036402 0.486932396619674 0.81280345050574 0.81280345050574 0.81280345050574 0.779300312905748 0.81280345050574
Pdss2 ENSMUSG00000038240 0.257590128588909 0.386385192883364 0.0282256487331422 0.0846769461994266 0.996848720880169 0.996848720880169
Mboat1 ENSMUSG00000038732 0.767161864604521 0.767161864604521 0.646812478218905 0.767161864604521 0.352627939276744 0.767161864604521
Tph1 ENSMUSG00000040046 0.938155113543858 0.938155113543858 0.713314649498837 0.938155113543858 0.445903249141294 0.938155113543858
Cyp2s1 ENSMUSG00000040703 0.803605682920622 0.946505656123509 0.946505656123509 0.946505656123509 0.940211175269926 0.946505656123509
Dhrs7b ENSMUSG00000042569 0.655424619368357 0.664044702914624 0.664044702914624 0.664044702914624 0.346760981390445 0.664044702914624
Liph ENSMUSG00000044626 0.660795262843052 0.914746069095443 0.914746069095443 0.914746069095443 0.299763421920552 0.899290265761657
Akr1b7 ENSMUSG00000052131 0.939153572947976 0.996792474614302 0.952040528311447 0.996792474614302 0.996792474614302 0.996792474614302
Ppap2c ENSMUSG00000052151 0.455290201122185 0.666978670869125 0.303936474764992 0.666978670869125 0.666978670869125 0.666978670869125
Mogat2 ENSMUSG00000052396 0.627771507062674 0.627771507062674 0.155748554566206 0.467245663698618 0.345327788768269 0.517991683152404
Lclat1 ENSMUSG00000054469 0.200983748863478 0.602951246590435 0.80973518982499 0.80973518982499 0.621591708076235 0.80973518982499
Fut2 ENSMUSG00000055978 0.694699667972788 0.817371478377464 0.817371478377464 0.817371478377464 0.684131790430368 0.817371478377464
Acbd4 ENSMUSG00000056938 0.0833448893797965 0.25003466813939 0.187215354305796 0.280823031458694 0.965351956090013 0.965351956090013
Ipmk ENSMUSG00000060733 0.324800937479879 0.679345324553285 0.452896883035524 0.679345324553285 0.990551398440706 0.990551398440706
Ext1 ENSMUSG00000061731 0.713543892033136 0.713543892033136 0.553606875091365 0.713543892033136 0.630019519345084 0.713543892033136
Duox2 ENSMUSG00000068452 0.386045489887011 0.570104276533995 0.570104276533995 0.570104276533995 0.285989088492114 0.570104276533995
Sco1 ENSMUSG00000069844 0.8189016079878 0.8189016079878 0.170538427578522 0.511615282735567 0.684154619279061 0.8189016079878
Mgst2 ENSMUSG00000074604 0.977879126168875 0.977879126168875 0.508732217037025 0.977879126168875 0.949349329530891 0.977879126168875
Csnk2a1 ENSMUSG00000074698 0.210971115955039 0.632913347865117 0.687065767635213 0.981100294205187 0.981100294205187 0.981100294205187
B3gnt7 ENSMUSG00000079445 0.943158889193063 0.943158889193063 0.805902961947636 0.943158889193063 0.883323694259756 0.943158889193063
Ugt1a7c ENSMUSG00000090124 0.459422054799653 0.854146325779094 0.955882693645803 0.955882693645803 0.569430883852729 0.854146325779094

O-linked glycosylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Muc13 ENSMUSG00000022824 0.536148802500162 0.536148802500162 0.127016136054218 0.381048408162653 0.396537000576402 0.536148802500162
Galnt3 ENSMUSG00000026994 0.987400304476363 0.987400304476363 0.666853256647925 0.987400304476363 0.454804061333491 0.987400304476363
Galnt7 ENSMUSG00000031608 0.169335132385826 0.508005397157478 0.767119791588071 0.98110373090371 0.98110373090371 0.98110373090371
B3gnt3 ENSMUSG00000031803 0.890105010732863 0.890105010732863 0.142482916164533 0.427448748493599 0.455018379120772 0.682527568681158
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Adamts15 ENSMUSG00000033453 0.591244020287811 0.664104214896561 0.638423143362934 0.664104214896561 0.664104214896561 0.664104214896561
Galnt6 ENSMUSG00000037280 0.734243232682629 0.734243232682629 0.602195408694262 0.734243232682629 0.481949492250282 0.734243232682629
Gyltl1b ENSMUSG00000040434 0.669460190448817 0.836777586878077 0.836777586878077 0.836777586878077 0.721541597642914 0.836777586878077
Adamtsl5 ENSMUSG00000043822 0.794232171100149 0.794232171100149 0.417868145134831 0.707727430428656 0.471818286952437 0.707727430428656
St6galnac2 ENSMUSG00000057286 0.779284082219453 0.779284082219453 0.280291718596716 0.623455032437237 0.415636688291491 0.623455032437237
B3gnt6 ENSMUSG00000074004 0.977876207817531 0.977876207817531 0.827890587351799 0.977876207817531 0.600640521017228 0.977876207817531
B3gnt7 ENSMUSG00000079445 0.943158889193063 0.943158889193063 0.805902961947636 0.943158889193063 0.883323694259756 0.943158889193063
Gcnt4 ENSMUSG00000091387 0.981078221363129 0.981078221363129 0.930803750314257 0.981078221363129 0.886832830838805 0.981078221363129

Glycerophospholipid biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Agpat3 ENSMUSG00000001211 0.731192092416326 0.731192092416326 0.106449390102905 0.319348170308714 0.230363270220595 0.345544905330892
Slc44a4 ENSMUSG00000007034 0.397900241125543 0.880075150078653 0.880075150078653 0.880075150078653 0.665572342615447 0.880075150078653
Ptdss1 ENSMUSG00000021518 0.877656701788645 0.877656701788645 0.0405081128048405 0.121524338414522 0.661030660177479 0.877656701788645
Dgat1 ENSMUSG00000022555 0.462378508745712 0.693567763118568 0.445713983168694 0.693567763118568 0.698835712587405 0.698835712587405
Lpin3 ENSMUSG00000027412 0.350877233309094 0.526315849963642 0.800516748498999 0.800516748498999 0.276725908369913 0.526315849963642
Acp6 ENSMUSG00000028093 0.955938842529787 0.955938842529787 0.417922550209206 0.955938842529787 0.794485564907848 0.955938842529787
Pla2g2f ENSMUSG00000028749 0.915203643611842 0.915203643611842 0.803716209326427 0.915203643611842 0.464345081213963 0.915203643611842
Plb1 ENSMUSG00000029134 0.519954693773021 0.779932040659531 0.952980447169958 0.952980447169958 0.363005787285086 0.779932040659531
Agpat9 ENSMUSG00000029314 0.0856777155669593 0.257033146700878 0.618686808543379 0.785289842664283 0.785289842664283 0.785289842664283
Pla2g4c ENSMUSG00000033847 0.230250324084723 0.404422750661083 0.303860573015806 0.404422750661083 0.404422750661083 0.404422750661083
Mboat1 ENSMUSG00000038732 0.767161864604521 0.767161864604521 0.646812478218905 0.767161864604521 0.352627939276744 0.767161864604521
Liph ENSMUSG00000044626 0.660795262843052 0.914746069095443 0.914746069095443 0.914746069095443 0.299763421920552 0.899290265761657
Lclat1 ENSMUSG00000054469 0.200983748863478 0.602951246590435 0.80973518982499 0.80973518982499 0.621591708076235 0.80973518982499
Csnk2a1 ENSMUSG00000074698 0.210971115955039 0.632913347865117 0.687065767635213 0.981100294205187 0.981100294205187 0.981100294205187

Transport of inorganic cations/anions and amino acids/oligopeptides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc7a7 ENSMUSG00000000958 0.174420391969767 0.261630587954651 0.303467860454927 0.303467860454927 0.12368397467234 0.261630587954651
Slc26a3 ENSMUSG00000001225 0.57469303476021 0.862039552140315 0.983929188570735 0.983929188570735 0.2534310281605 0.7602930844815
Slc12a4 ENSMUSG00000017765 0.34680608760272 0.499303265789525 0.0417630564290916 0.125289169287275 0.499303265789525 0.499303265789525
Slc5a8 ENSMUSG00000020062 0.536190647912096 0.536190647912096 0.504485915253185 0.536190647912096 0.488441175570384 0.536190647912096
Slc6a19 ENSMUSG00000021565 1 1 0.582902829398259 0.874354244097389 0.486780613861072 0.874354244097389
Slc26a6 ENSMUSG00000023259 0.0427744564776817 0.128323369433045 0.104504514943076 0.156756772414614 0.532449303840237 0.532449303840237
Slc15a1 ENSMUSG00000025557 0.701230330178935 0.99003672266318 0.99003672266318 0.99003672266318 0.941460073281463 0.99003672266318
Slc9a2 ENSMUSG00000026062 0.918260729530517 0.918260729530517 0.72826886686269 0.918260729530517 0.785340030441985 0.918260729530517
Slc34a2 ENSMUSG00000029188 0.463545808152237 0.899397094493345 0.899397094493345 0.899397094493345 0.811062715960212 0.899397094493345
Slc7a9 ENSMUSG00000030492 0.960748588186069 0.960748588186069 0.498264459931539 0.747396689897308 0.31636548300845 0.747396689897308
Slc26a2 ENSMUSG00000034320 0.90247265456362 0.977924570676233 0.971666140526556 0.977924570676233 0.977924570676233 0.977924570676233
Slc9a3 ENSMUSG00000036123 0.477231542692887 0.71584731403933 0.966584200819459 0.966584200819459 0.377614390638735 0.71584731403933
Slc20a2 ENSMUSG00000037656 0.532627139143593 0.532627139143593 0.126088110930639 0.378264332791916 0.292867443801955 0.439301165702933

Cell junction organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Jup ENSMUSG00000001552 0.190060250508939 0.295328587106757 0.196885724737838 0.295328587106757 0.943368515910083 0.943368515910083
Fblim1 ENSMUSG00000006219 0.902435526106509 0.902435526106509 0.837305768310116 0.902435526106509 0.843280202789753 0.902435526106509
Itgb4 ENSMUSG00000020758 0.764124772141379 0.990548344843438 0.990548344843438 0.990548344843438 0.496550570487596 0.990548344843438
Pvrl3 ENSMUSG00000022656 0.698867805561052 0.87145141855491 0.87145141855491 0.87145141855491 0.71944180253573 0.87145141855491
Lama3 ENSMUSG00000024421 0.905264770638921 0.987398279748739 0.987398279748739 0.987398279748739 0.455176189612559 0.987398279748739
Lamb3 ENSMUSG00000026639 0.315619256291641 0.618034055354613 0.896370902542841 0.896370902542841 0.412022703569742 0.618034055354613
Cdh17 ENSMUSG00000028217 0.324982169219185 0.599294507590996 0.634040994823919 0.634040994823919 0.39952967172733 0.599294507590996
Ctnnd1 ENSMUSG00000034101 0.890106633204879 0.890106633204879 0.0947306902234862 0.284192070670459 0.672559498007883 0.890106633204879
Ctnna1 ENSMUSG00000037815 0.610510184662866 0.610510184662866 0.153900395921686 0.461701187765059 0.558920555230168 0.610510184662866
Pard6b ENSMUSG00000044641 0.540342955478868 0.886965568027449 0.849708007584369 0.886965568027449 0.886965568027449 0.886965568027449

Signaling by MST1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Spint1 ENSMUSG00000027315 0.410699198147399 0.911935712761414 0.855883808833477 0.911935712761414 0.911935712761414 0.911935712761414
Mst1r ENSMUSG00000032584 0.481518356404953 0.72227753460743 0.946471405369964 0.946471405369964 0.380088118658718 0.72227753460743
Spint2 ENSMUSG00000074227 0.224461340376967 0.336692010565451 0.205343491023635 0.336692010565451 0.943366274994689 0.943366274994689

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Neu1 ENSMUSG00000007038 0.61879264316566 0.984253153889948 0.684251668796809 0.984253153889948 0.984253153889948 0.984253153889948
Tsta3 ENSMUSG00000022570 0.0367365312689306 0.110209593806792 0.462501201214523 0.583063795513227 0.583063795513227 0.583063795513227
St6galnac6 ENSMUSG00000026811 0.740221592894354 0.933943501145503 0.42019228812206 0.933943501145503 0.933943501145503 0.933943501145503
Dolpp1 ENSMUSG00000026856 0.752136817819924 0.886949277587635 0.886949277587635 0.886949277587635 0.782180492597579 0.886949277587635
Gfpt1 ENSMUSG00000029992 0.322940567966185 0.921407679645115 0.921407679645115 0.921407679645115 0.755165907034892 0.921407679645115
St3gal4 ENSMUSG00000032038 0.874566058709269 0.874566058709269 0.5019473781759 0.874566058709269 0.599497002456168 0.874566058709269
Gmds ENSMUSG00000038372 0.701723443319335 0.952780102682691 0.361186146827202 0.952780102682691 0.952780102682691 0.952780102682691
St3gal5 ENSMUSG00000056091 0.93080461359939 0.93080461359939 0.206712406396208 0.620137219188626 0.687170397241485 0.93080461359939
Pgm3 ENSMUSG00000056131 0.794438413901895 0.794438413901895 0.558892648149637 0.794438413901895 0.776219665474985 0.794438413901895
St6galnac2 ENSMUSG00000057286 0.779284082219453 0.779284082219453 0.280291718596716 0.623455032437237 0.415636688291491 0.623455032437237

darkorange2

Lysosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppt2 ENSMUSG00000015474 0.360634979477108 0.540952469215662 0.0746015090378291 0.223804527113487 0.652282116590338 0.652282116590338
Galc ENSMUSG00000021003 0.70468084102578 0.981102173222328 0.494190406172114 0.981102173222328 0.981102173222328 0.981102173222328
Lgmn ENSMUSG00000021190 0.716423550524123 0.755126350000552 0.545636715736434 0.755126350000552 0.755126350000552 0.755126350000552
Gm21685 ENSMUSG00000022066 0.232037065326186 0.348055597989278 0.0597557194078544 0.179267158223563 0.519716499704027 0.519716499704027
Slc11a2 ENSMUSG00000023030 0.464830906976829 0.666888183936455 0.271414541867136 0.666888183936455 0.666888183936455 0.666888183936455
Tpp1 ENSMUSG00000030894 0.521911824577958 0.782867736866937 0.95276940807475 0.95276940807475 0.381990229974154 0.782867736866937
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Gnptg ENSMUSG00000035521 0.415617792334786 0.650878407139698 0.433918938093132 0.650878407139698 0.707655288285447 0.707655288285447
Arsb ENSMUSG00000042082 0.812796084898896 0.818930763199929 0.809723955750547 0.818930763199929 0.818930763199929 0.818930763199929
Entpd4 ENSMUSG00000095463 0.58034877233536 0.770179803097483 0.577637938548197 0.770179803097483 0.770179803097483 0.770179803097483

mTOR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Igf1r ENSMUSG00000005533 0.794476433476694 0.971666289143896 0.971666289143896 0.971666289143896 0.749183566503767 0.971666289143896
Gatsl3 ENSMUSG00000020424 0.949639510136028 0.949639510136028 0.363165640808322 0.741515937578665 0.494343958385777 0.741515937578665
Sesn2 ENSMUSG00000028893 0.773231976485352 0.91827123426571 0.652664676081363 0.91827123426571 0.91827123426571 0.91827123426571
Mtor ENSMUSG00000028991 0.868322760981301 0.868322760981301 0.230562123311039 0.679228753878935 0.452819169252623 0.679228753878935
Wnt5b ENSMUSG00000030170 0.283802612230999 0.283802612230999 0.136219058480824 0.283802612230999 0.194105782584785 0.283802612230999
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Fzd1 ENSMUSG00000044674 0.887010787896046 0.887010787896046 0.450526700356935 0.887010787896046 0.852836116173632 0.887010787896046
Atp6v1a ENSMUSG00000052459 0.216901592763803 0.650704778291409 0.946510444910997 0.946510444910997 0.618815657817144 0.928223486725716
Fnip2 ENSMUSG00000061175 0.479545015100749 0.577698840491089 0.577698840491089 0.577698840491089 0.512080597097484 0.577698840491089

ECM-receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb8 ENSMUSG00000025321 0.751214955311841 0.987333347628724 0.595049858395748 0.987333347628724 0.987333347628724 0.987333347628724
Lamc3 ENSMUSG00000026840 0.405967857786551 0.806261608552419 0.537507739034946 0.806261608552419 0.824862005772902 0.824862005772902
Itgav ENSMUSG00000027087 0.420145622538046 0.768040916935921 0.512027277957281 0.768040916935921 0.977961089878667 0.977961089878667
Col4a5 ENSMUSG00000031274 0.334605108777861 0.501907663166792 0.292878750936179 0.501907663166792 0.713458617333069 0.713458617333069
Lama1 ENSMUSG00000032796 0.77594088760576 0.77594088760576 0.727908347440095 0.77594088760576 0.6894871813426 0.77594088760576
Frem2 ENSMUSG00000037016 0.871396075639009 0.871396075639009 0.0929393186848963 0.278817956054689 0.529501520520038 0.794252280780056

SLC-mediated transmembrane transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc13a3 ENSMUSG00000018459 0.785166012750936 0.861816175336367 0.626799106396417 0.861816175336367 0.861816175336367 0.861816175336367
Slc35b4 ENSMUSG00000018999 0.65550673924692 0.65550673924692 0.34266308669158 0.65550673924692 0.569582854646587 0.65550673924692
Slc6a15 ENSMUSG00000019894 0.821694673711639 0.852473856165745 0.84640756075178 0.852473856165745 0.852473856165745 0.852473856165745
Slc29a3 ENSMUSG00000020100 0.880787569542553 0.887019509610745 0.887019509610745 0.887019509610745 0.431750355400185 0.887019509610745
Slc36a1 ENSMUSG00000020261 0.974811463962597 0.974811463962597 0.776219227425501 0.974811463962597 0.849723931559851 0.974811463962597
Slc26a4 ENSMUSG00000020651 0.929660569984587 0.961593385242582 0.949367615110038 0.961593385242582 0.961593385242582 0.961593385242582
Slc11a2 ENSMUSG00000023030 0.464830906976829 0.666888183936455 0.271414541867136 0.666888183936455 0.666888183936455 0.666888183936455
Slc6a6 ENSMUSG00000030096 0.596203244196706 0.788325224664061 0.788325224664061 0.788325224664061 0.652301721893324 0.788325224664061
Slc9a8 ENSMUSG00000039463 0.596445702866419 0.874557460769063 0.874557460769063 0.874557460769063 0.403809349564146 0.874557460769063
Slco4c1 ENSMUSG00000040693 0.967929641996009 0.967929641996009 0.638403898487015 0.967929641996009 0.730507436621765 0.967929641996009
Slc4a4 ENSMUSG00000060961 0.924540004764056 0.965373047812775 0.809744463211032 0.965373047812775 0.965373047812775 0.965373047812775
Slc22a8 ENSMUSG00000063796 0.690768827273638 0.922874171824427 0.922874171824427 0.922874171824427 0.851803211536819 0.922874171824427
Slc5a3 ENSMUSG00000089774 0.378131828555453 0.981108717957913 0.930803364908675 0.981108717957913 0.981108717957913 0.981108717957913

Amino acids regulate mTORC1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gatsl3 ENSMUSG00000020424 0.949639510136028 0.949639510136028 0.363165640808322 0.741515937578665 0.494343958385777 0.741515937578665
Sesn2 ENSMUSG00000028893 0.773231976485352 0.91827123426571 0.652664676081363 0.91827123426571 0.91827123426571 0.91827123426571
Mtor ENSMUSG00000028991 0.868322760981301 0.868322760981301 0.230562123311039 0.679228753878935 0.452819169252623 0.679228753878935
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Atp6v1a ENSMUSG00000052459 0.216901592763803 0.650704778291409 0.946510444910997 0.946510444910997 0.618815657817144 0.928223486725716
Fnip2 ENSMUSG00000061175 0.479545015100749 0.577698840491089 0.577698840491089 0.577698840491089 0.512080597097484 0.577698840491089

Cellular response to starvation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gatsl3 ENSMUSG00000020424 0.949639510136028 0.949639510136028 0.363165640808322 0.741515937578665 0.494343958385777 0.741515937578665
Sesn2 ENSMUSG00000028893 0.773231976485352 0.91827123426571 0.652664676081363 0.91827123426571 0.91827123426571 0.91827123426571
Mtor ENSMUSG00000028991 0.868322760981301 0.868322760981301 0.230562123311039 0.679228753878935 0.452819169252623 0.679228753878935
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Atp6v1a ENSMUSG00000052459 0.216901592763803 0.650704778291409 0.946510444910997 0.946510444910997 0.618815657817144 0.928223486725716
Fnip2 ENSMUSG00000061175 0.479545015100749 0.577698840491089 0.577698840491089 0.577698840491089 0.512080597097484 0.577698840491089

Transport of small molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Steap2 ENSMUSG00000015653 0.707517027898535 0.707517027898535 0.687179831605508 0.707517027898535 0.663932887252912 0.707517027898535
Slc13a3 ENSMUSG00000018459 0.785166012750936 0.861816175336367 0.626799106396417 0.861816175336367 0.861816175336367 0.861816175336367
Slc35b4 ENSMUSG00000018999 0.65550673924692 0.65550673924692 0.34266308669158 0.65550673924692 0.569582854646587 0.65550673924692
Slc6a15 ENSMUSG00000019894 0.821694673711639 0.852473856165745 0.84640756075178 0.852473856165745 0.852473856165745 0.852473856165745
Slc29a3 ENSMUSG00000020100 0.880787569542553 0.887019509610745 0.887019509610745 0.887019509610745 0.431750355400185 0.887019509610745
Slc36a1 ENSMUSG00000020261 0.974811463962597 0.974811463962597 0.776219227425501 0.974811463962597 0.849723931559851 0.974811463962597
Slc26a4 ENSMUSG00000020651 0.929660569984587 0.961593385242582 0.949367615110038 0.961593385242582 0.961593385242582 0.961593385242582
Slc11a2 ENSMUSG00000023030 0.464830906976829 0.666888183936455 0.271414541867136 0.666888183936455 0.666888183936455 0.666888183936455
Abca3 ENSMUSG00000024130 0.344309599373992 0.514239384909509 0.241555887064707 0.514239384909509 0.514239384909509 0.514239384909509
Fth1 ENSMUSG00000024661 0.710596990202083 0.710596990202083 0.020826889156299 0.062480667468897 0.561585321284856 0.710596990202083
Nceh1 ENSMUSG00000027698 0.399610655569338 0.399610655569338 0.223988264311439 0.399610655569338 0.356619381518946 0.399610655569338
Slc6a6 ENSMUSG00000030096 0.596203244196706 0.788325224664061 0.788325224664061 0.788325224664061 0.652301721893324 0.788325224664061
Atp11a ENSMUSG00000031441 0.71649020034611 0.877677478538589 0.877677478538589 0.877677478538589 0.877676692657204 0.877677478538589
Abcc4 ENSMUSG00000032849 0.880775532573475 0.880775532573475 0.203880843582967 0.611642530748901 0.749165156801571 0.880775532573475
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Slc9a8 ENSMUSG00000039463 0.596445702866419 0.874557460769063 0.874557460769063 0.874557460769063 0.403809349564146 0.874557460769063
Slco4c1 ENSMUSG00000040693 0.967929641996009 0.967929641996009 0.638403898487015 0.967929641996009 0.730507436621765 0.967929641996009
Atp6v1a ENSMUSG00000052459 0.216901592763803 0.650704778291409 0.946510444910997 0.946510444910997 0.618815657817144 0.928223486725716
Slc4a4 ENSMUSG00000060961 0.924540004764056 0.965373047812775 0.809744463211032 0.965373047812775 0.965373047812775 0.965373047812775
Slc22a8 ENSMUSG00000063796 0.690768827273638 0.922874171824427 0.922874171824427 0.922874171824427 0.851803211536819 0.922874171824427
Slc5a3 ENSMUSG00000089774 0.378131828555453 0.981108717957913 0.930803364908675 0.981108717957913 0.981108717957913 0.981108717957913

Transport of bile salts and organic acids, metal ions and amine compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc13a3 ENSMUSG00000018459 0.785166012750936 0.861816175336367 0.626799106396417 0.861816175336367 0.861816175336367 0.861816175336367
Slc6a15 ENSMUSG00000019894 0.821694673711639 0.852473856165745 0.84640756075178 0.852473856165745 0.852473856165745 0.852473856165745
Slc11a2 ENSMUSG00000023030 0.464830906976829 0.666888183936455 0.271414541867136 0.666888183936455 0.666888183936455 0.666888183936455
Slc6a6 ENSMUSG00000030096 0.596203244196706 0.788325224664061 0.788325224664061 0.788325224664061 0.652301721893324 0.788325224664061
Slc22a8 ENSMUSG00000063796 0.690768827273638 0.922874171824427 0.922874171824427 0.922874171824427 0.851803211536819 0.922874171824427
Slc5a3 ENSMUSG00000089774 0.378131828555453 0.981108717957913 0.930803364908675 0.981108717957913 0.981108717957913 0.981108717957913

Iron uptake and transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Steap2 ENSMUSG00000015653 0.707517027898535 0.707517027898535 0.687179831605508 0.707517027898535 0.663932887252912 0.707517027898535
Slc11a2 ENSMUSG00000023030 0.464830906976829 0.666888183936455 0.271414541867136 0.666888183936455 0.666888183936455 0.666888183936455
Fth1 ENSMUSG00000024661 0.710596990202083 0.710596990202083 0.020826889156299 0.062480667468897 0.561585321284856 0.710596990202083
Atp6v1h ENSMUSG00000033793 0.618824203937737 0.918257108778524 0.564091028259166 0.918257108778524 0.918257108778524 0.918257108778524
Atp6v1a ENSMUSG00000052459 0.216901592763803 0.650704778291409 0.946510444910997 0.946510444910997 0.618815657817144 0.928223486725716

floralwhite

Cardiac muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox4i2 ENSMUSG00000009876 0.254209339444796 0.381314009167193 0.160757674569536 0.381314009167193 0.585571208641018 0.585571208641018
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Calcium signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pde1c ENSMUSG00000004347 0.959043308455255 0.959043308455255 0.846556735232964 0.959043308455255 0.737189850100705 0.959043308455255
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Chrm2 ENSMUSG00000045613 0.594415747474544 0.873383653756093 0.873383653756093 0.873383653756093 0.833069091091042 0.873383653756093
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Arrhythmogenic right ventricular cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Hypertrophic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

cAMP signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Cnga3 ENSMUSG00000026114 0.801695628100736 0.898859431863269 0.471285527005613 0.898859431863269 0.898859431863269 0.898859431863269
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Chrm2 ENSMUSG00000045613 0.594415747474544 0.873383653756093 0.873383653756093 0.873383653756093 0.833069091091042 0.873383653756093
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Adrenergic signaling in cardiomyocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Thyroid hormone signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rxra ENSMUSG00000015846 0.438678968538166 0.658018452807249 0.328819615501723 0.658018452807249 0.731259564624044 0.731259564624044
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Rcan2 ENSMUSG00000039601 0.785223503394183 0.785223503394183 0.719350522809964 0.785223503394183 0.690024236976432 0.785223503394183

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox4i2 ENSMUSG00000009876 0.254209339444796 0.381314009167193 0.160757674569536 0.381314009167193 0.585571208641018 0.585571208641018
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Fzd7 ENSMUSG00000041075 0.278394189541144 0.417591284311716 0.150304181491188 0.417591284311716 0.782260252153629 0.782260252153629
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Cushing syndrome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fzd7 ENSMUSG00000041075 0.278394189541144 0.417591284311716 0.150304181491188 0.417591284311716 0.782260252153629 0.782260252153629
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

cGMP-PKG signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981
Slc8a1 ENSMUSG00000054640 0.445657614135715 0.800534943412855 0.776247670967115 0.800534943412855 0.800534943412855 0.800534943412855

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox4i2 ENSMUSG00000009876 0.254209339444796 0.381314009167193 0.160757674569536 0.381314009167193 0.585571208641018 0.585571208641018
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Fzd7 ENSMUSG00000041075 0.278394189541144 0.417591284311716 0.150304181491188 0.417591284311716 0.782260252153629 0.782260252153629
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox4i2 ENSMUSG00000009876 0.254209339444796 0.381314009167193 0.160757674569536 0.381314009167193 0.585571208641018 0.585571208641018
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941

Cortisol synthesis and secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Cardiac conduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607
Cacna1c ENSMUSG00000051331 0.812756533757292 0.831179249429981 0.725276536163447 0.831179249429981 0.831179249429981 0.831179249429981

Potassium Channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcna5 ENSMUSG00000045534 0.525171245512654 0.867398677126665 0.668164030143117 0.867398677126665 0.867398677126665 0.867398677126665
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607
Kcng2 ENSMUSG00000059852 0.865834281094619 0.865834281094619 0.339512334719113 0.865834281094619 0.781901745686761 0.865834281094619

Transcriptional regulation of white adipocyte differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rxra ENSMUSG00000015846 0.438678968538166 0.658018452807249 0.328819615501723 0.658018452807249 0.731259564624044 0.731259564624044

Voltage gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcna5 ENSMUSG00000045534 0.525171245512654 0.867398677126665 0.668164030143117 0.867398677126665 0.867398677126665 0.867398677126665
Kcng2 ENSMUSG00000059852 0.865834281094619 0.865834281094619 0.339512334719113 0.865834281094619 0.781901745686761 0.865834281094619

Ion homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ryr2 ENSMUSG00000021313 0.703137211806361 0.89611183593916 0.89611183593916 0.89611183593916 0.805798532936231 0.89611183593916
Atp2a2 ENSMUSG00000029467 0.669455349693557 0.669455349693557 0.256256898952363 0.544318857658941 0.362879238439294 0.544318857658941

TWIK-releated acid-sensitive K+ channel (TASK)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnk3 ENSMUSG00000049265 0.94628675558728 0.977951893946607 0.977951893946607 0.977951893946607 0.899071834627723 0.977951893946607

grey

Starch and sucrose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Pancreatic secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cpb1 ENSMUSG00000011463 0.757886894705974 0.86434725130325 0.704259549076274 0.86434725130325 0.86434725130325 0.86434725130325
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Carbohydrate digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Salivary secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pde6g ENSMUSG00000025386 0.629826072780474 0.629826072780474 0.459718094455649 0.629826072780474 0.361071072216448 0.629826072780474
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Digestion of dietary carbohydrate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Digestion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

Digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a3 ENSMUSG00000093931 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a2 ENSMUSG00000096569 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007
Amy2a4 ENSMUSG00000096770 0.446013937878167 0.9381563261007 0.9381563261007 0.9381563261007 0.716858551728228 0.9381563261007

ivory

[1] “No significantly overrepresented pathways reported”

lightcyan

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Inmt ENSMUSG00000003477 0.601809187751552 0.890110902524723 0.775923615686409 0.890110902524723 0.890110902524723 0.890110902524723
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Cyp2a5 ENSMUSG00000005547 0.228807485036167 0.6864224551085 0.820783484467043 0.820783484467043 0.469677684088712 0.704516526133068
Cs ENSMUSG00000005683 0.635185370878013 0.721991032456085 0.059147166678989 0.177441500036967 0.721991032456085 0.721991032456085
Fpgs ENSMUSG00000009566 0.192646428316882 0.577939284950645 0.63836116950232 0.843517980487116 0.843517980487116 0.843517980487116
Sardh ENSMUSG00000009614 0.377986004941987 0.377986004941987 0.334714040090688 0.377986004941987 0.294385272591804 0.377986004941987
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Entpd2 ENSMUSG00000015085 0.280178615247619 0.420267922871429 0.440994929724804 0.440994929724804 0.179544596307204 0.420267922871429
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Glyctk ENSMUSG00000020258 0.527165105504078 0.946473000860054 0.908875797086874 0.946473000860054 0.946473000860054 0.946473000860054
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Dpys ENSMUSG00000022304 0.701432565185327 0.701432565185327 0.325463577539774 0.701432565185327 0.547783882987625 0.701432565185327
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Cpox ENSMUSG00000022742 0.534876670833082 0.678139874632344 0.0564619885562064 0.169385965668619 0.678139874632344 0.678139874632344
Nit2 ENSMUSG00000022751 0.203872310254799 0.611616930764396 0.843528437396436 0.843528437396436 0.506892129284936 0.760338193927404
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Csad ENSMUSG00000023044 0.152247599188862 0.438640574271354 0.292427049514236 0.438640574271354 0.649623935290187 0.649623935290187
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Hagh ENSMUSG00000024158 0.776207228736979 0.776207228736979 0.0468838651124892 0.106347498655441 0.070898332436961 0.106347498655441
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Keg1 ENSMUSG00000024694 0.855660623898523 0.855660623898523 0.672021452948654 0.855660623898523 0.686992010184348 0.855660623898523
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Pcx ENSMUSG00000024892 0.450298008568543 0.675447012852814 0.292829136480503 0.675447012852814 0.90569555097996 0.90569555097996
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Inpp5a ENSMUSG00000025477 0.800488508164396 0.930786647526838 0.361254872585581 0.930786647526838 0.930786647526838 0.930786647526838
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Asl ENSMUSG00000025533 0.406546491296678 0.657820492087881 0.438546994725254 0.657820492087881 0.782254180124743 0.782254180124743
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Uck2 ENSMUSG00000026558 0.219844849493282 0.560195310691575 0.37346354046105 0.560195310691575 0.965343607765579 0.965343607765579
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Pet112 ENSMUSG00000028085 0.924532250542767 0.924532250542767 0.761162542948346 0.924532250542767 0.591257453761128 0.924532250542767
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Fam213b ENSMUSG00000029059 0.319109697057608 0.745372327631021 0.496914885087348 0.745372327631021 0.946502500665274 0.946502500665274
Paics ENSMUSG00000029247 0.627182428406564 0.828129184848196 0.413393726931514 0.828129184848196 0.828129184848196 0.828129184848196
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Aass ENSMUSG00000029695 0.800517053970291 0.800517053970291 0.558837697560168 0.800517053970291 0.767156685673837 0.800517053970291
Pik3c2g ENSMUSG00000030228 0.35099124501824 0.531630544765169 0.65684422875596 0.65684422875596 0.354420363176779 0.531630544765169
Gys2 ENSMUSG00000030244 0.56209234881425 0.658835959864134 0.658835959864134 0.658835959864134 0.590513962110454 0.658835959864134
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Acsm5 ENSMUSG00000030972 0.417500833995922 0.643665987310722 0.643665987310722 0.643665987310722 0.5037827510796 0.643665987310722
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Ldhd ENSMUSG00000031958 0.837395980479901 0.855936468395073 0.464895142764851 0.855936468395073 0.855936468395073 0.855936468395073
Acad8 ENSMUSG00000031969 0.0217222590777258 0.0651667772331773 0.101478405734058 0.152217608601086 0.48442016917389 0.48442016917389
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Cdo1 ENSMUSG00000033022 0.912000449281769 0.912000449281769 0.905739286274942 0.912000449281769 0.577584287393076 0.912000449281769
Upb1 ENSMUSG00000033427 0.800574632062202 0.893252824864311 0.68138990426433 0.893252824864311 0.893252824864311 0.893252824864311
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Cml2 ENSMUSG00000033634 0.263143691777485 0.540715738136446 0.604349070426977 0.604349070426977 0.360477158757631 0.540715738136446
Uroc1 ENSMUSG00000034456 0.422395689198618 0.623698406250281 0.623698406250281 0.623698406250281 0.231115155829334 0.623698406250281
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Xylb ENSMUSG00000035769 0.962216595358935 0.981099825419181 0.981099825419181 0.981099825419181 0.855848484404524 0.981099825419181
Hykk ENSMUSG00000035878 0.797508403758094 0.877646397582197 0.877646397582197 0.877646397582197 0.809691117504969 0.877646397582197
Acss3 ENSMUSG00000035948 0.946504719684719 0.946504719684719 0.740147984991553 0.946504719684719 0.661176288154687 0.946504719684719
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699
Aldh8a1 ENSMUSG00000037542 0.540300133817929 0.810450200726894 0.395466321726339 0.810450200726894 0.889803180868197 0.889803180868197
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028
Aspdh ENSMUSG00000038704 0.621224840274258 0.76998188777252 0.76998188777252 0.76998188777252 0.663741403089801 0.76998188777252
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Dmgdh ENSMUSG00000042102 0.228597908172092 0.430548453040675 0.579012117323109 0.579012117323109 0.287032302027117 0.430548453040675
Bhmt2 ENSMUSG00000042118 0.29379503069154 0.68560935285955 0.457072901906367 0.68560935285955 0.778958425421416 0.778958425421416
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165
Gpat2 ENSMUSG00000046338 0.485990697472251 0.539193629109169 0.438014726948473 0.539193629109169 0.539193629109169 0.539193629109169
Cyp2j5 ENSMUSG00000052520 0.721965966404182 0.721965966404182 0.287308798950182 0.560895684208604 0.373930456139069 0.560895684208604
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Cml1 ENSMUSG00000057103 0.367446854934441 0.604844857690255 0.462393937489245 0.604844857690255 0.604844857690255 0.604844857690255
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482
Pla2g16 ENSMUSG00000060675 0.186031670149917 0.558095010449751 0.53247288008769 0.798709320131535 0.968507313125324 0.968507313125324
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794
Dhrs3 ENSMUSG00000066026 0.474490315029488 0.711735472544232 0.0980399957268955 0.294119987180686 0.731270790627875 0.731270790627875
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Mthfs ENSMUSG00000066442 0.0822140063582019 0.246642019074606 0.501941353269316 0.655513363909937 0.655513363909937 0.655513363909937
Selenbp1 ENSMUSG00000068874 0.222796309771267 0.356957296245318 0.356957296245318 0.356957296245318 0.340695276959796 0.356957296245318
Selenbp2 ENSMUSG00000068877 0.640388079034177 0.889905424428775 0.159715595580873 0.479146786742619 0.889905424428775 0.889905424428775
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Ass1 ENSMUSG00000076441 0.517074166738437 0.78835890752577 0.540458763637347 0.78835890752577 0.78835890752577 0.78835890752577
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995
Vkorc1 ENSMUSG00000096145 0.224396055089374 0.336594082634062 0.0858255368344354 0.257476610503306 0.371509437492091 0.371509437492091

Pyruvate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Hagh ENSMUSG00000024158 0.776207228736979 0.776207228736979 0.0468838651124892 0.106347498655441 0.070898332436961 0.106347498655441
Pcx ENSMUSG00000024892 0.450298008568543 0.675447012852814 0.292829136480503 0.675447012852814 0.90569555097996 0.90569555097996
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Ldhd ENSMUSG00000031958 0.837395980479901 0.855936468395073 0.464895142764851 0.855936468395073 0.855936468395073 0.855936468395073
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Glyoxylate and dicarboxylate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cs ENSMUSG00000005683 0.635185370878013 0.721991032456085 0.059147166678989 0.177441500036967 0.721991032456085 0.721991032456085
Glyctk ENSMUSG00000020258 0.527165105504078 0.946473000860054 0.908875797086874 0.946473000860054 0.946473000860054 0.946473000860054
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1

Valine, leucine and isoleucine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Acad8 ENSMUSG00000031969 0.0217222590777258 0.0651667772331773 0.101478405734058 0.152217608601086 0.48442016917389 0.48442016917389
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

Tryptophan metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Inmt ENSMUSG00000003477 0.601809187751552 0.890110902524723 0.775923615686409 0.890110902524723 0.890110902524723 0.890110902524723
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Aldh8a1 ENSMUSG00000037542 0.540300133817929 0.810450200726894 0.395466321726339 0.810450200726894 0.889803180868197 0.889803180868197
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1

Fatty acid degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Peroxisome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pxmp4 ENSMUSG00000000876 0.39325304923841 0.39325304923841 0.285535576286673 0.39325304923841 0.359145896134869 0.39325304923841
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pex7 ENSMUSG00000020003 0.0554310251496499 0.0831465377244748 0.0103191356451538 0.0309574069354614 0.965361211182397 0.965361211182397
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Sod1 ENSMUSG00000022982 0.206664986665087 0.309997479997631 0.133144278575236 0.309997479997631 0.588532228367926 0.588532228367926
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454

Glycine, serine and threonine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sardh ENSMUSG00000009614 0.377986004941987 0.377986004941987 0.334714040090688 0.377986004941987 0.294385272591804 0.377986004941987
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Glyctk ENSMUSG00000020258 0.527165105504078 0.946473000860054 0.908875797086874 0.946473000860054 0.946473000860054 0.946473000860054
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Dmgdh ENSMUSG00000042102 0.228597908172092 0.430548453040675 0.579012117323109 0.579012117323109 0.287032302027117 0.430548453040675
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

Retinol metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2a5 ENSMUSG00000005547 0.228807485036167 0.6864224551085 0.820783484467043 0.820783484467043 0.469677684088712 0.704516526133068
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Retsat ENSMUSG00000056666 0.246270685006654 0.585655109398768 0.585655109398768 0.585655109398768 0.522246535148787 0.585655109398768
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Dhrs3 ENSMUSG00000066026 0.474490315029488 0.711735472544232 0.0980399957268955 0.294119987180686 0.731270790627875 0.731270790627875
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Biosynthesis of cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Fpgs ENSMUSG00000009566 0.192646428316882 0.577939284950645 0.63836116950232 0.843517980487116 0.843517980487116 0.843517980487116
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Cpox ENSMUSG00000022742 0.534876670833082 0.678139874632344 0.0564619885562064 0.169385965668619 0.678139874632344 0.678139874632344
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Aspdh ENSMUSG00000038704 0.621224840274258 0.76998188777252 0.76998188777252 0.76998188777252 0.663741403089801 0.76998188777252
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Dhrs3 ENSMUSG00000066026 0.474490315029488 0.711735472544232 0.0980399957268955 0.294119987180686 0.731270790627875 0.731270790627875
Vkorc1 ENSMUSG00000096145 0.224396055089374 0.336594082634062 0.0858255368344354 0.257476610503306 0.371509437492091 0.371509437492091

Carbon metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cs ENSMUSG00000005683 0.635185370878013 0.721991032456085 0.059147166678989 0.177441500036967 0.721991032456085 0.721991032456085
Glyctk ENSMUSG00000020258 0.527165105504078 0.946473000860054 0.908875797086874 0.946473000860054 0.946473000860054 0.946473000860054
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Pcx ENSMUSG00000024892 0.450298008568543 0.675447012852814 0.292829136480503 0.675447012852814 0.90569555097996 0.90569555097996
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312

Propanoate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Acss3 ENSMUSG00000035948 0.946504719684719 0.946504719684719 0.740147984991553 0.946504719684719 0.661176288154687 0.946504719684719
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1

Glycolysis / Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866

Tyrosine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Drug metabolism - other enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Tpmt ENSMUSG00000021376 0.803632472807513 0.987404948649505 0.987404948649505 0.987404948649505 0.905752789866191 0.987404948649505
Dpys ENSMUSG00000022304 0.701432565185327 0.701432565185327 0.325463577539774 0.701432565185327 0.547783882987625 0.701432565185327
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Uck2 ENSMUSG00000026558 0.219844849493282 0.560195310691575 0.37346354046105 0.560195310691575 0.965343607765579 0.965343607765579
Upb1 ENSMUSG00000033427 0.800574632062202 0.893252824864311 0.68138990426433 0.893252824864311 0.893252824864311 0.893252824864311
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482
Ces1e ENSMUSG00000061959 0.556490537566352 0.834735806349529 0.946281006544174 0.946281006544174 0.506861544980423 0.834735806349529

Lysine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Aass ENSMUSG00000029695 0.800517053970291 0.800517053970291 0.558837697560168 0.800517053970291 0.767156685673837 0.800517053970291
Hykk ENSMUSG00000035878 0.797508403758094 0.877646397582197 0.877646397582197 0.877646397582197 0.809691117504969 0.877646397582197
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551
Acat3 ENSMUSG00000062480 0.326473098136255 0.979419294408765 0.924479015468855 1 1 1

Pantothenate and CoA biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Dpys ENSMUSG00000022304 0.701432565185327 0.701432565185327 0.325463577539774 0.701432565185327 0.547783882987625 0.701432565185327
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Upb1 ENSMUSG00000033427 0.800574632062202 0.893252824864311 0.68138990426433 0.893252824864311 0.893252824864311 0.893252824864311
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879

Chemical carcinogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Arachidonic acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Fam213b ENSMUSG00000029059 0.319109697057608 0.745372327631021 0.496914885087348 0.745372327631021 0.946502500665274 0.946502500665274
Cyp2j5 ENSMUSG00000052520 0.721965966404182 0.721965966404182 0.287308798950182 0.560895684208604 0.373930456139069 0.560895684208604
Pla2g16 ENSMUSG00000060675 0.186031670149917 0.558095010449751 0.53247288008769 0.798709320131535 0.968507313125324 0.968507313125324
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Cysteine and methionine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Cdo1 ENSMUSG00000033022 0.912000449281769 0.912000449281769 0.905739286274942 0.912000449281769 0.577584287393076 0.912000449281769
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Bhmt2 ENSMUSG00000042118 0.29379503069154 0.68560935285955 0.457072901906367 0.68560935285955 0.778958425421416 0.778958425421416
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

PPAR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Ppara ENSMUSG00000022383 0.971638919973417 0.971638919973417 0.658218437782807 0.971638919973417 0.890028416673354 0.971638919973417
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Drug metabolism - cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Fmo1 ENSMUSG00000040181 0.610520715722041 0.962227143817173 0.962227143817173 0.962227143817173 0.794480718894451 0.962227143817173
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Metabolism of xenobiotics by cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Glucagon signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppara ENSMUSG00000022383 0.971638919973417 0.971638919973417 0.658218437782807 0.971638919973417 0.890028416673354 0.971638919973417
Gcgr ENSMUSG00000025127 0.691480836312877 0.94918775256434 0.94918775256434 0.94918775256434 0.655268180452428 0.94918775256434
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Slc2a2 ENSMUSG00000027690 0.767313055675579 0.767313055675579 0.649249290097259 0.767313055675579 0.669293689419284 0.767313055675579
Gys2 ENSMUSG00000030244 0.56209234881425 0.658835959864134 0.658835959864134 0.658835959864134 0.590513962110454 0.658835959864134
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Camk2d ENSMUSG00000053819 0.354940102208834 0.675495128730178 0.669717107139201 0.675495128730178 0.675495128730178 0.675495128730178
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866

beta-Alanine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Dpys ENSMUSG00000022304 0.701432565185327 0.701432565185327 0.325463577539774 0.701432565185327 0.547783882987625 0.701432565185327
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Upb1 ENSMUSG00000033427 0.800574632062202 0.893252824864311 0.68138990426433 0.893252824864311 0.893252824864311 0.893252824864311
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788

Steroid hormone biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Srd5a1 ENSMUSG00000021594 0.899476374764054 0.899476374764054 0.48672247809665 0.882716621483239 0.588477747655493 0.882716621483239
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Cyp2d9 ENSMUSG00000068086 0.876876170960465 0.876876170960465 0.353384542541419 0.876876170960465 0.673602280251913 0.876876170960465

Glutathione metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Cml2 ENSMUSG00000033634 0.263143691777485 0.540715738136446 0.604349070426977 0.604349070426977 0.360477158757631 0.540715738136446
Cml1 ENSMUSG00000057103 0.367446854934441 0.604844857690255 0.462393937489245 0.604844857690255 0.604844857690255 0.604844857690255
Gsta2 ENSMUSG00000057933 0.987363083087482 0.987363083087482 0.420384191175275 0.987363083087482 0.751221211150736 0.987363083087482

Arginine and proline metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
L3hypdh ENSMUSG00000019718 0.616052752713458 0.785350344408475 0.785350344408475 0.785350344408475 0.553580759251606 0.785350344408475
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788

Phenylalanine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Keg1 ENSMUSG00000024694 0.855660623898523 0.855660623898523 0.672021452948654 0.855660623898523 0.686992010184348 0.855660623898523
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794

Alanine, aspartate and glutamate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nit2 ENSMUSG00000022751 0.203872310254799 0.611616930764396 0.843528437396436 0.843528437396436 0.506892129284936 0.760338193927404
Asl ENSMUSG00000025533 0.406546491296678 0.657820492087881 0.438546994725254 0.657820492087881 0.782254180124743 0.782254180124743
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Ass1 ENSMUSG00000076441 0.517074166738437 0.78835890752577 0.540458763637347 0.78835890752577 0.78835890752577 0.78835890752577
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

Sulfur metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165
Selenbp1 ENSMUSG00000068874 0.222796309771267 0.356957296245318 0.356957296245318 0.356957296245318 0.340695276959796 0.356957296245318
Selenbp2 ENSMUSG00000068877 0.640388079034177 0.889905424428775 0.159715595580873 0.479146786742619 0.889905424428775 0.889905424428775

Biosynthesis of amino acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cs ENSMUSG00000005683 0.635185370878013 0.721991032456085 0.059147166678989 0.177441500036967 0.721991032456085 0.721991032456085
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Pcx ENSMUSG00000024892 0.450298008568543 0.675447012852814 0.292829136480503 0.675447012852814 0.90569555097996 0.90569555097996
Asl ENSMUSG00000025533 0.406546491296678 0.657820492087881 0.438546994725254 0.657820492087881 0.782254180124743 0.782254180124743
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Ass1 ENSMUSG00000076441 0.517074166738437 0.78835890752577 0.540458763637347 0.78835890752577 0.78835890752577 0.78835890752577

Nicotinate and nicotinamide metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028
Aspdh ENSMUSG00000038704 0.621224840274258 0.76998188777252 0.76998188777252 0.76998188777252 0.663741403089801 0.76998188777252

Inflammatory mediator regulation of TRP channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppp1cb ENSMUSG00000014956 0.0062325033206576 0.0186975099619728 0.834212087971636 0.834212087971636 0.812618884512662 0.834212087971636
Cyp2c44 ENSMUSG00000025197 0.271202394215769 0.813607182647307 0.72566798664545 0.910176506840674 0.910176506840674 0.910176506840674
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp2j5 ENSMUSG00000052520 0.721965966404182 0.721965966404182 0.287308798950182 0.560895684208604 0.373930456139069 0.560895684208604
Camk2d ENSMUSG00000053819 0.354940102208834 0.675495128730178 0.669717107139201 0.675495128730178 0.675495128730178 0.675495128730178
Kng2 ENSMUSG00000060459 0.616016680268126 0.616016680268126 0.518796242515696 0.616016680268126 0.505437146034319 0.616016680268126
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Insulin resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Insr ENSMUSG00000005534 0.85583110743155 0.85583110743155 0.113099492451239 0.339298477353717 0.388781726703718 0.583172590055577
Ppp1cb ENSMUSG00000014956 0.0062325033206576 0.0186975099619728 0.834212087971636 0.834212087971636 0.812618884512662 0.834212087971636
Ppara ENSMUSG00000022383 0.971638919973417 0.971638919973417 0.658218437782807 0.971638919973417 0.890028416673354 0.971638919973417
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Slc2a2 ENSMUSG00000027690 0.767313055675579 0.767313055675579 0.649249290097259 0.767313055675579 0.669293689419284 0.767313055675579
Gys2 ENSMUSG00000030244 0.56209234881425 0.658835959864134 0.658835959864134 0.658835959864134 0.590513962110454 0.658835959864134
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866

Insulin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Raf1 ENSMUSG00000000441 0.256261379347498 0.384392069021247 0.0478014302010051 0.143404290603015 0.477080496785617 0.477080496785617
Insr ENSMUSG00000005534 0.85583110743155 0.85583110743155 0.113099492451239 0.339298477353717 0.388781726703718 0.583172590055577
Ppp1cb ENSMUSG00000014956 0.0062325033206576 0.0186975099619728 0.834212087971636 0.834212087971636 0.812618884512662 0.834212087971636
Inpp5a ENSMUSG00000025477 0.800488508164396 0.930786647526838 0.361254872585581 0.930786647526838 0.930786647526838 0.930786647526838
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Eif4e ENSMUSG00000028156 0.0829419748561966 0.24882592456859 0.752144959379698 0.868336035482512 0.868336035482512 0.868336035482512
Gys2 ENSMUSG00000030244 0.56209234881425 0.658835959864134 0.658835959864134 0.658835959864134 0.590513962110454 0.658835959864134
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866

Primary bile acid biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Cs ENSMUSG00000005683 0.635185370878013 0.721991032456085 0.059147166678989 0.177441500036967 0.721991032456085 0.721991032456085
Fpgs ENSMUSG00000009566 0.192646428316882 0.577939284950645 0.63836116950232 0.843517980487116 0.843517980487116 0.843517980487116
Sardh ENSMUSG00000009614 0.377986004941987 0.377986004941987 0.334714040090688 0.377986004941987 0.294385272591804 0.377986004941987
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Entpd2 ENSMUSG00000015085 0.280178615247619 0.420267922871429 0.440994929724804 0.440994929724804 0.179544596307204 0.420267922871429
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Sdc2 ENSMUSG00000022261 0.883897791587318 0.883897791587318 0.737237739929715 0.883897791587318 0.812799244625015 0.883897791587318
Dpys ENSMUSG00000022304 0.701432565185327 0.701432565185327 0.325463577539774 0.701432565185327 0.547783882987625 0.701432565185327
Hrsp12 ENSMUSG00000022323 0.855939157131469 0.965374701345978 0.965374701345978 0.965374701345978 0.905755397726704 0.965374701345978
Has2 ENSMUSG00000022367 0.485703502266749 0.544442467017119 0.544442467017119 0.544442467017119 0.36280939745944 0.544442467017119
Ppara ENSMUSG00000022383 0.971638919973417 0.971638919973417 0.658218437782807 0.971638919973417 0.890028416673354 0.971638919973417
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Cpox ENSMUSG00000022742 0.534876670833082 0.678139874632344 0.0564619885562064 0.169385965668619 0.678139874632344 0.678139874632344
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Prkd3 ENSMUSG00000024070 0.438531049182702 0.459924766302992 0.459924766302992 0.459924766302992 0.231756891237749 0.459924766302992
Lrpprc ENSMUSG00000024120 0.348485940971546 0.348485940971546 7.75157785150018e-05 0.000232547335545005 0.27644807641833 0.348485940971546
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Slc23a1 ENSMUSG00000024354 0.961027977424967 0.961027977424967 0.948791066198335 0.961027977424967 0.532746774513803 0.961027977424967
Apom ENSMUSG00000024391 0.760641034581041 0.876159616565181 0.872829069845806 0.876159616565181 0.876159616565181 0.876159616565181
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Asl ENSMUSG00000025533 0.406546491296678 0.657820492087881 0.438546994725254 0.657820492087881 0.782254180124743 0.782254180124743
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Uck2 ENSMUSG00000026558 0.219844849493282 0.560195310691575 0.37346354046105 0.560195310691575 0.965343607765579 0.965343607765579
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Slc2a2 ENSMUSG00000027690 0.767313055675579 0.767313055675579 0.649249290097259 0.767313055675579 0.669293689419284 0.767313055675579
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Paics ENSMUSG00000029247 0.627182428406564 0.828129184848196 0.413393726931514 0.828129184848196 0.828129184848196 0.828129184848196
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Aass ENSMUSG00000029695 0.800517053970291 0.800517053970291 0.558837697560168 0.800517053970291 0.767156685673837 0.800517053970291
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Acsm5 ENSMUSG00000030972 0.417500833995922 0.643665987310722 0.643665987310722 0.643665987310722 0.5037827510796 0.643665987310722
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Slc37a4 ENSMUSG00000032114 0.262588075504087 0.602208313494389 0.450186526729819 0.602208313494389 0.602208313494389 0.602208313494389
Pkm ENSMUSG00000032294 0.874549764182574 0.930804706092309 0.52484925350428 0.930804706092309 0.930804706092309 0.930804706092309
Cdo1 ENSMUSG00000033022 0.912000449281769 0.912000449281769 0.905739286274942 0.912000449281769 0.577584287393076 0.912000449281769
Upb1 ENSMUSG00000033427 0.800574632062202 0.893252824864311 0.68138990426433 0.893252824864311 0.893252824864311 0.893252824864311
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Uroc1 ENSMUSG00000034456 0.422395689198618 0.623698406250281 0.623698406250281 0.623698406250281 0.231115155829334 0.623698406250281
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Xylb ENSMUSG00000035769 0.962216595358935 0.981099825419181 0.981099825419181 0.981099825419181 0.855848484404524 0.981099825419181
Hykk ENSMUSG00000035878 0.797508403758094 0.877646397582197 0.877646397582197 0.877646397582197 0.809691117504969 0.877646397582197
Acss3 ENSMUSG00000035948 0.946504719684719 0.946504719684719 0.740147984991553 0.946504719684719 0.661176288154687 0.946504719684719
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699
Aspg ENSMUSG00000037686 0.48681445237297 0.940117217158363 0.680782736939026 0.940117217158363 0.940117217158363 0.940117217158363
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028
Bphl ENSMUSG00000038286 0.0306967085159942 0.0460450627739914 0.0119009690097929 0.0357029070293788 0.445755472612083 0.445755472612083
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Hs3st6 ENSMUSG00000039628 0.160489625753631 0.481468877260892 0.544015795058819 0.816023692588228 0.920963528194033 0.920963528194033
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Fmo1 ENSMUSG00000040181 0.610520715722041 0.962227143817173 0.962227143817173 0.962227143817173 0.794480718894451 0.962227143817173
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Dmgdh ENSMUSG00000042102 0.228597908172092 0.430548453040675 0.579012117323109 0.579012117323109 0.287032302027117 0.430548453040675
Bhmt2 ENSMUSG00000042118 0.29379503069154 0.68560935285955 0.457072901906367 0.68560935285955 0.778958425421416 0.778958425421416
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165
Gpat2 ENSMUSG00000046338 0.485990697472251 0.539193629109169 0.438014726948473 0.539193629109169 0.539193629109169 0.539193629109169
Slc26a1 ENSMUSG00000046959 0.671004455735891 0.908345483514561 0.554941559405819 0.908345483514561 0.908345483514561 0.908345483514561
Ugt3a2 ENSMUSG00000049152 0.357411593637387 0.53611739045608 0.225382990220694 0.53611739045608 0.56739325343016 0.56739325343016
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551
Pla2g16 ENSMUSG00000060675 0.186031670149917 0.558095010449751 0.53247288008769 0.798709320131535 0.968507313125324 0.968507313125324
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Mthfs ENSMUSG00000066442 0.0822140063582019 0.246642019074606 0.501941353269316 0.655513363909937 0.655513363909937 0.655513363909937
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
Slc25a16 ENSMUSG00000071253 0.987399234505484 0.987399234505484 0.927665388650777 0.987399234505484 0.74005319026121 0.987399234505484
Ugt3a1 ENSMUSG00000072664 0.86297103830561 0.929702261850322 0.929702261850322 0.929702261850322 0.853825992222396 0.929702261850322
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Ass1 ENSMUSG00000076441 0.517074166738437 0.78835890752577 0.540458763637347 0.78835890752577 0.78835890752577 0.78835890752577
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995
Vkorc1 ENSMUSG00000096145 0.224396055089374 0.336594082634062 0.0858255368344354 0.257476610503306 0.371509437492091 0.371509437492091

Metabolism of amino acids and derivatives

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Sardh ENSMUSG00000009614 0.377986004941987 0.377986004941987 0.334714040090688 0.377986004941987 0.294385272591804 0.377986004941987
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Hrsp12 ENSMUSG00000022323 0.855939157131469 0.965374701345978 0.965374701345978 0.965374701345978 0.905755397726704 0.965374701345978
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Asl ENSMUSG00000025533 0.406546491296678 0.657820492087881 0.438546994725254 0.657820492087881 0.782254180124743 0.782254180124743
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Aass ENSMUSG00000029695 0.800517053970291 0.800517053970291 0.558837697560168 0.800517053970291 0.767156685673837 0.800517053970291
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Cdo1 ENSMUSG00000033022 0.912000449281769 0.912000449281769 0.905739286274942 0.912000449281769 0.577584287393076 0.912000449281769
Uroc1 ENSMUSG00000034456 0.422395689198618 0.623698406250281 0.623698406250281 0.623698406250281 0.231115155829334 0.623698406250281
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Hykk ENSMUSG00000035878 0.797508403758094 0.877646397582197 0.877646397582197 0.877646397582197 0.809691117504969 0.877646397582197
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699
Aspg ENSMUSG00000037686 0.48681445237297 0.940117217158363 0.680782736939026 0.940117217158363 0.940117217158363 0.940117217158363
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Dmgdh ENSMUSG00000042102 0.228597908172092 0.430548453040675 0.579012117323109 0.579012117323109 0.287032302027117 0.430548453040675
Bhmt2 ENSMUSG00000042118 0.29379503069154 0.68560935285955 0.457072901906367 0.68560935285955 0.778958425421416 0.778958425421416
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551
Ass1 ENSMUSG00000076441 0.517074166738437 0.78835890752577 0.540458763637347 0.78835890752577 0.78835890752577 0.78835890752577
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

Biological oxidations

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Acsm5 ENSMUSG00000030972 0.417500833995922 0.643665987310722 0.643665987310722 0.643665987310722 0.5037827510796 0.643665987310722
Bphl ENSMUSG00000038286 0.0306967085159942 0.0460450627739914 0.0119009690097929 0.0357029070293788 0.445755472612083 0.445755472612083
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Fmo1 ENSMUSG00000040181 0.610520715722041 0.962227143817173 0.962227143817173 0.962227143817173 0.794480718894451 0.962227143817173
Slc26a1 ENSMUSG00000046959 0.671004455735891 0.908345483514561 0.554941559405819 0.908345483514561 0.908345483514561 0.908345483514561
Ugt3a2 ENSMUSG00000049152 0.357411593637387 0.53611739045608 0.225382990220694 0.53611739045608 0.56739325343016 0.56739325343016
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Ugt3a1 ENSMUSG00000072664 0.86297103830561 0.929702261850322 0.929702261850322 0.929702261850322 0.853825992222396 0.929702261850322
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Peroxisomal protein import

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pex7 ENSMUSG00000020003 0.0554310251496499 0.0831465377244748 0.0103191356451538 0.0309574069354614 0.965361211182397 0.965361211182397
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636

Protein localization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pxmp4 ENSMUSG00000000876 0.39325304923841 0.39325304923841 0.285535576286673 0.39325304923841 0.359145896134869 0.39325304923841
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Pex7 ENSMUSG00000020003 0.0554310251496499 0.0831465377244748 0.0103191356451538 0.0309574069354614 0.965361211182397 0.965361211182397
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Cat ENSMUSG00000027187 0.85902542860026 0.85902542860026 0.176928908202128 0.530786724606384 0.638448546835907 0.85902542860026
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Ldhd ENSMUSG00000031958 0.837395980479901 0.855936468395073 0.464895142764851 0.855936468395073 0.855936468395073 0.855936468395073
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636

Phenylalanine and tyrosine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393

Phase II - Conjugation of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Comt ENSMUSG00000000326 0.855875685080549 0.855875685080549 0.38455606908793 0.854359847551409 0.569573231700939 0.854359847551409
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Acsm5 ENSMUSG00000030972 0.417500833995922 0.643665987310722 0.643665987310722 0.643665987310722 0.5037827510796 0.643665987310722
Slc26a1 ENSMUSG00000046959 0.671004455735891 0.908345483514561 0.554941559405819 0.908345483514561 0.908345483514561 0.908345483514561
Ugt3a2 ENSMUSG00000049152 0.357411593637387 0.53611739045608 0.225382990220694 0.53611739045608 0.56739325343016 0.56739325343016
Ugt1a6a ENSMUSG00000054545 0.661043564292443 0.974810316703511 0.974810316703511 0.974810316703511 0.615890350366854 0.974810316703511
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794
Ugt3a1 ENSMUSG00000072664 0.86297103830561 0.929702261850322 0.929702261850322 0.929702261850322 0.853825992222396 0.929702261850322

Lysine catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gcdh ENSMUSG00000003809 0.408838207094566 0.924529233899776 0.924529233899776 0.924529233899776 0.725324366443933 0.924529233899776
Pipox ENSMUSG00000017453 0.874563586461677 0.965371962069856 0.548328472121367 0.965371962069856 0.965371962069856 0.965371962069856
Aass ENSMUSG00000029695 0.800517053970291 0.800517053970291 0.558837697560168 0.800517053970291 0.767156685673837 0.800517053970291
Hykk ENSMUSG00000035878 0.797508403758094 0.877646397582197 0.877646397582197 0.877646397582197 0.809691117504969 0.877646397582197
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551

Metabolism of vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Fpgs ENSMUSG00000009566 0.192646428316882 0.577939284950645 0.63836116950232 0.843517980487116 0.843517980487116 0.843517980487116
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Sdc2 ENSMUSG00000022261 0.883897791587318 0.883897791587318 0.737237739929715 0.883897791587318 0.812799244625015 0.883897791587318
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Slc23a1 ENSMUSG00000024354 0.961027977424967 0.961027977424967 0.948791066198335 0.961027977424967 0.532746774513803 0.961027977424967
Apom ENSMUSG00000024391 0.760641034581041 0.876159616565181 0.872829069845806 0.876159616565181 0.876159616565181 0.876159616565181
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Mthfs ENSMUSG00000066442 0.0822140063582019 0.246642019074606 0.501941353269316 0.655513363909937 0.655513363909937 0.655513363909937
Slc25a16 ENSMUSG00000071253 0.987399234505484 0.987399234505484 0.927665388650777 0.987399234505484 0.74005319026121 0.987399234505484
Vkorc1 ENSMUSG00000096145 0.224396055089374 0.336594082634062 0.0858255368344354 0.257476610503306 0.371509437492091 0.371509437492091

Metabolism of water-soluble vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Fpgs ENSMUSG00000009566 0.192646428316882 0.577939284950645 0.63836116950232 0.843517980487116 0.843517980487116 0.843517980487116
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Slc23a1 ENSMUSG00000024354 0.961027977424967 0.961027977424967 0.948791066198335 0.961027977424967 0.532746774513803 0.961027977424967
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Mthfs ENSMUSG00000066442 0.0822140063582019 0.246642019074606 0.501941353269316 0.655513363909937 0.655513363909937 0.655513363909937
Slc25a16 ENSMUSG00000071253 0.987399234505484 0.987399234505484 0.927665388650777 0.987399234505484 0.74005319026121 0.987399234505484

Phase I - Functionalization of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Bphl ENSMUSG00000038286 0.0306967085159942 0.0460450627739914 0.0119009690097929 0.0357029070293788 0.445755472612083 0.445755472612083
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Fmo1 ENSMUSG00000040181 0.610520715722041 0.962227143817173 0.962227143817173 0.962227143817173 0.794480718894451 0.962227143817173
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Tyrosine catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Hgd ENSMUSG00000022821 0.657257545397981 0.930334297602289 0.930334297602289 0.930334297602289 0.662459701487692 0.930334297602289
Hpd ENSMUSG00000029445 0.93900683596856 0.93900683596856 0.498689730741993 0.93900683596856 0.725854963391442 0.93900683596856
Fah ENSMUSG00000030630 0.30208774932965 0.822416834210881 0.548277889473921 0.822416834210881 0.859003956514323 0.859003956514323

Glyoxylate metabolism and glycine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Gldc ENSMUSG00000024827 0.877067401859963 0.877067401859963 0.744854857245979 0.877067401859963 0.711576095969457 0.877067401859963
Hoga1 ENSMUSG00000025176 0.67843995681158 0.758164293145067 0.684248798001684 0.758164293145067 0.758164293145067 0.758164293145067
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Grhpr ENSMUSG00000035637 0.110890209849732 0.166335314774598 0.00745149166456118 0.0223544749936836 0.175539715657943 0.175539715657943
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699
Agxt2 ENSMUSG00000089678 0.499924021228347 0.815027647133995 0.815027647133995 0.815027647133995 0.575795886981157 0.815027647133995

Fatty acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Peroxisomal lipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541

Tryptophan catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Haao ENSMUSG00000000673 0.0982458069959012 0.294737420987704 0.611716951432939 0.611716951432939 0.555333158951134 0.611716951432939
Ido2 ENSMUSG00000031549 0.733606247533557 0.958905972497537 0.694921239155861 0.958905972497537 0.958905972497537 0.958905972497537
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393
Aadat ENSMUSG00000057228 0.844558477945551 0.844558477945551 0.433562213002658 0.844558477945551 0.648010221771466 0.844558477945551

Ethanol oxidation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acss2 ENSMUSG00000027605 0.479402552030585 0.479402552030585 0.0468984219156466 0.14069526574694 0.350800115012759 0.479402552030585
Adh5 ENSMUSG00000028138 0.44785546324136 0.671783194862039 0.97795783225133 0.97795783225133 0.410927697833227 0.671783194862039
Aldh2 ENSMUSG00000029455 0.285554108261211 0.428331162391816 0.112739805577838 0.338219416733513 0.831226826589132 0.831226826589132
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Sulfur amino acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cbs ENSMUSG00000024039 0.317004650508143 0.825023045211148 0.825023045211148 0.825023045211148 0.602190213956042 0.825023045211148
Ahcy ENSMUSG00000027597 0.90575408858684 1 1 1 0.915141303472893 1
Cdo1 ENSMUSG00000033022 0.912000449281769 0.912000449281769 0.905739286274942 0.912000449281769 0.577584287393076 0.912000449281769
Bhmt2 ENSMUSG00000042118 0.29379503069154 0.68560935285955 0.457072901906367 0.68560935285955 0.778958425421416 0.778958425421416
Tst ENSMUSG00000044986 0.143798220285804 0.431394660857413 0.457694599464553 0.68654189919683 0.81280632265165 0.81280632265165

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104

Alpha-oxidation of phytanate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541

Choline catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sardh ENSMUSG00000009614 0.377986004941987 0.377986004941987 0.334714040090688 0.377986004941987 0.294385272591804 0.377986004941987
Dmgdh ENSMUSG00000042102 0.228597908172092 0.430548453040675 0.579012117323109 0.579012117323109 0.287032302027117 0.430548453040675
Aldh7a1 ENSMUSG00000053644 0.45758001292178 0.686370019382671 0.259586867825397 0.686370019382671 0.899486258539788 0.899486258539788

Metabolism of lipids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acaa1b ENSMUSG00000010651 0.13889412874751 0.416682386242529 0.660993717125274 0.691247951790921 0.691247951790921 0.691247951790921
Hsd11b1 ENSMUSG00000016194 0.58311545914729 0.58311545914729 0.512053467840469 0.58311545914729 0.359170433856582 0.58311545914729
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Hacl1 ENSMUSG00000021884 0.550978299141315 0.550978299141315 0.411045595987196 0.550978299141315 0.175554672713333 0.526664018139998
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Ppara ENSMUSG00000022383 0.971638919973417 0.971638919973417 0.658218437782807 0.971638919973417 0.890028416673354 0.971638919973417
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Prkd3 ENSMUSG00000024070 0.438531049182702 0.459924766302992 0.459924766302992 0.459924766302992 0.231756891237749 0.459924766302992
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Pecr ENSMUSG00000026189 0.305683209743777 0.710586092815931 0.710586092815931 0.710586092815931 0.602134276506539 0.710586092815931
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Hmgcl ENSMUSG00000028672 0.0767289758086328 0.115093463712949 0.0169273361988084 0.0507820085964251 0.54828540414454 0.54828540414454
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Acss3 ENSMUSG00000035948 0.946504719684719 0.946504719684719 0.740147984991553 0.946504719684719 0.661176288154687 0.946504719684719
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Gpat2 ENSMUSG00000046338 0.485990697472251 0.539193629109169 0.438014726948473 0.539193629109169 0.539193629109169 0.539193629109169
Pla2g16 ENSMUSG00000060675 0.186031670149917 0.558095010449751 0.53247288008769 0.798709320131535 0.968507313125324 0.968507313125324
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Coenzyme A biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Slc25a16 ENSMUSG00000071253 0.987399234505484 0.987399234505484 0.927665388650777 0.987399234505484 0.74005319026121 0.987399234505484

Eicosanoids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Synthesis of bile acids and bile salts

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104

Cytochrome P450 - arranged by substrate type

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.549769885220822 0.902277578326568 0.902277578326568 0.902277578326568 0.626303114382897 0.902277578326568
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Glutathione conjugation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt1 ENSMUSG00000001663 0.613244847693859 0.868309088857567 0.868309088857567 0.868309088857567 0.506953243587346 0.868309088857567
Chac2 ENSMUSG00000020309 0.180782965054921 0.271174447582381 0.10057244017931 0.271174447582381 0.413428383173148 0.413428383173148
Gstz1 ENSMUSG00000021033 0.209467287534126 0.628401862602377 0.424822269797862 0.637233404696793 0.840413668869332 0.840413668869332
Oplah ENSMUSG00000022562 0.21696151003938 0.32544226505907 0.152748337248602 0.32544226505907 0.641299301499862 0.641299301499862
Gsta3 ENSMUSG00000025934 0.946507916496047 0.946507916496047 0.924537467892989 0.946507916496047 0.868347427077892 0.946507916496047

RA biosynthesis pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh8a1 ENSMUSG00000037542 0.540300133817929 0.810450200726894 0.395466321726339 0.810450200726894 0.889803180868197 0.889803180868197
Cyp26b1 ENSMUSG00000063415 0.426730951291343 0.621534172372083 0.0121386663649926 0.0364159990949779 0.621534172372083 0.621534172372083
Dhrs3 ENSMUSG00000066026 0.474490315029488 0.711735472544232 0.0980399957268955 0.294119987180686 0.731270790627875 0.731270790627875
Adh1 ENSMUSG00000074207 0.834267804950516 0.977960706124526 0.977960706124526 0.977960706124526 0.494289134186135 0.977960706124526

Mitochondrial Fatty Acid Beta-Oxidation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acot3 ENSMUSG00000021228 0.811743513034706 0.811743513034706 0.771755883672813 0.811743513034706 0.636790613618925 0.811743513034706
Acot12 ENSMUSG00000021620 0.990493997472195 0.990493997472195 0.748444548973861 0.990493997472195 0.90829876981183 0.990493997472195
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324
Acot1 ENSMUSG00000072949 0.0144691417769585 0.0433055102538739 0.0288703401692493 0.0433055102538739 0.278549485051636 0.278549485051636

Proline catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh4a1 ENSMUSG00000028737 0.0502763405689822 0.150829021706947 0.126049427864237 0.189074141796355 0.830962713697726 0.830962713697726
Prodh2 ENSMUSG00000036892 0.417223942248192 0.813481940001699 0.813481940001699 0.813481940001699 0.801169990399718 0.813481940001699

Fatty acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Bile acid and bile salt metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox2 ENSMUSG00000021751 0.645864634081474 0.645864634081474 0.275841060014901 0.645864634081474 0.537952806180995 0.645864634081474
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059
Cyp7b1 ENSMUSG00000039519 0.874555307534699 0.984257272830104 0.949648911835097 0.984257272830104 0.984257272830104 0.984257272830104

Assembly of collagen fibrils and other multimeric structures

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.481952482196683 0.722928723295024 0.134160370817291 0.402481112451874 0.831192438386663 0.831192438386663
Col6a2 ENSMUSG00000020241 0.365364134419754 0.684255641047139 0.50181032977184 0.684255641047139 0.684255641047139 0.684255641047139
Ctsl ENSMUSG00000021477 0.646894286663178 0.849749697770894 0.849749697770894 0.849749697770894 0.511994286915863 0.849749697770894
Plec ENSMUSG00000022565 0.952786924670576 0.952786924670576 0.652663842170933 0.952786924670576 0.908856370048157 0.952786924670576
Col5a1 ENSMUSG00000026837 0.558851107387239 0.558851107387239 0.527391726030112 0.558851107387239 0.469747348316395 0.558851107387239
Col27a1 ENSMUSG00000045672 0.940227448119024 0.971666589533508 0.971666589533508 0.971666589533508 0.887020111033866 0.971666589533508

Post-translational protein phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Igfbp4 ENSMUSG00000017493 0.574878452396816 0.599496309004723 0.585740635921652 0.599496309004723 0.599496309004723 0.599496309004723
Sdc2 ENSMUSG00000022261 0.883897791587318 0.883897791587318 0.737237739929715 0.883897791587318 0.812799244625015 0.883897791587318
Fstl1 ENSMUSG00000022816 0.111764334977734 0.313310016326941 0.208873344217961 0.313310016326941 0.32252959358997 0.32252959358997
Proc ENSMUSG00000024386 0.687358974745011 0.898230536771676 0.898230536771676 0.898230536771676 0.810686208515326 0.898230536771676
Spp2 ENSMUSG00000026295 0.0955690154701664 0.286707046410499 0.546943202695776 0.546943202695776 0.402127159049172 0.546943202695776
Spp1 ENSMUSG00000029304 0.687192839698732 0.996851043272071 0.996851043272071 0.996851043272071 0.828145981777794 0.996851043272071
Eva1a ENSMUSG00000035104 0.474623346637274 0.846644100093799 0.846644100093799 0.846644100093799 0.840476987343742 0.846644100093799
Notum ENSMUSG00000042988 0.417624233611761 0.993685369726395 0.703809033210958 0.993685369726395 0.993685369726395 0.993685369726395

Nicotinate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nadk2 ENSMUSG00000022253 0.95593160210303 0.95593160210303 0.307657924937822 0.922973774813465 0.770202532752228 0.95593160210303
Nudt12 ENSMUSG00000024228 0.361209004002255 0.755165007020941 0.755165007020941 0.755165007020941 0.607697528224512 0.755165007020941
Qprt ENSMUSG00000030674 0.243142171803735 0.66983048732229 0.652633055803549 0.66983048732229 0.66983048732229 0.66983048732229
Nmrk1 ENSMUSG00000037847 0.770078797943028 0.770078797943028 0.227445357966439 0.682336073899317 0.618542389719575 0.770078797943028

Miscellaneous substrates

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Vitamin B5 (pantothenate) metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coasy ENSMUSG00000001755 0.399205870590112 0.519265609447488 0.225553792071071 0.519265609447488 0.519265609447488 0.519265609447488
Pank1 ENSMUSG00000033610 0.25092920068413 0.376393801026195 0.0676850807009288 0.203055242102786 0.519609735061879 0.519609735061879
Slc25a16 ENSMUSG00000071253 0.987399234505484 0.987399234505484 0.927665388650777 0.987399234505484 0.74005319026121 0.987399234505484

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Igfbp4 ENSMUSG00000017493 0.574878452396816 0.599496309004723 0.585740635921652 0.599496309004723 0.599496309004723 0.599496309004723
Sdc2 ENSMUSG00000022261 0.883897791587318 0.883897791587318 0.737237739929715 0.883897791587318 0.812799244625015 0.883897791587318
Fstl1 ENSMUSG00000022816 0.111764334977734 0.313310016326941 0.208873344217961 0.313310016326941 0.32252959358997 0.32252959358997
Proc ENSMUSG00000024386 0.687358974745011 0.898230536771676 0.898230536771676 0.898230536771676 0.810686208515326 0.898230536771676
Spp2 ENSMUSG00000026295 0.0955690154701664 0.286707046410499 0.546943202695776 0.546943202695776 0.402127159049172 0.546943202695776
Spp1 ENSMUSG00000029304 0.687192839698732 0.996851043272071 0.996851043272071 0.996851043272071 0.828145981777794 0.996851043272071
Eva1a ENSMUSG00000035104 0.474623346637274 0.846644100093799 0.846644100093799 0.846644100093799 0.840476987343742 0.846644100093799
Notum ENSMUSG00000042988 0.417624233611761 0.993685369726395 0.703809033210958 0.993685369726395 0.993685369726395 0.993685369726395

Synthesis of Leukotrienes (LT) and Eoxins (EX)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4a14 ENSMUSG00000028715 0.867810438812207 0.969200775094167 0.969200775094167 0.969200775094167 0.902815847895658 0.969200775094167
Cyp4a12a ENSMUSG00000066071 0.700925591003927 0.983463639274862 0.316066708070438 0.948200124211314 0.983463639274862 0.983463639274862
Cyp4a10 ENSMUSG00000066072 0.522808043205786 0.784212064808678 0.453778294694013 0.784212064808678 0.860712936783178 0.860712936783178
Cyp4a12b ENSMUSG00000078597 0.457148672692332 0.685723009038498 0.855604144441346 0.855604144441346 0.312158528001988 0.685723009038498

Synthesis of bile acids and bile salts via 24-hydroxycholesterol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amacr ENSMUSG00000022244 0.476748387675378 0.715122581513066 0.202322750634718 0.606968251904154 0.933909083166529 0.933909083166529
Slc27a2 ENSMUSG00000027359 0.719313835721402 0.971666080446541 0.971666080446541 0.971666080446541 0.710437017884394 0.971666080446541
Akr1c14 ENSMUSG00000033715 0.233862608952137 0.701587826856411 0.86462914987059 0.86462914987059 0.738611817097003 0.86462914987059

Signaling by PDGF

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col6a2 ENSMUSG00000020241 0.365364134419754 0.684255641047139 0.50181032977184 0.684255641047139 0.684255641047139 0.684255641047139
Thbs2 ENSMUSG00000023885 0.809735335708974 0.930811919397469 0.930811919397469 0.930811919397469 0.489388537277399 0.930811919397469
Col5a1 ENSMUSG00000026837 0.558851107387239 0.558851107387239 0.527391726030112 0.558851107387239 0.469747348316395 0.558851107387239
Spp1 ENSMUSG00000029304 0.687192839698732 0.996851043272071 0.996851043272071 0.996851043272071 0.828145981777794 0.996851043272071
Furin ENSMUSG00000030530 0.946485401378501 0.946485401378501 0.326772422754962 0.771464310115938 0.514309540077292 0.771464310115938

Phenylalanine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pah ENSMUSG00000020051 0.599142057740194 0.599142057740194 0.212868389731013 0.599142057740194 0.571644772483583 0.599142057740194
Ccbl1 ENSMUSG00000039648 0.893243072523393 0.893243072523393 0.607642009872838 0.893243072523393 0.41314007832355 0.893243072523393

Conjugation of salicylate with glycine

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acsm5 ENSMUSG00000030972 0.417500833995922 0.643665987310722 0.643665987310722 0.643665987310722 0.5037827510796 0.643665987310722
Glyat ENSMUSG00000063683 0.639001057171582 0.965164861288794 0.666597688072803 0.965164861288794 0.965164861288794 0.965164861288794

Propionyl-CoA catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mut ENSMUSG00000023921 0.728252156714391 0.758174079715222 0.397623534060766 0.758174079715222 0.758174079715222 0.758174079715222
Pcca ENSMUSG00000041650 0.291056790194076 0.722395655592324 0.722395655592324 0.722395655592324 0.669849575116303 0.722395655592324

Branched-chain amino acid catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dbt ENSMUSG00000000340 0.274867247041045 0.824601741123134 0.800529184410245 0.871428176684944 0.871428176684944 0.871428176684944
Aldh6a1 ENSMUSG00000021238 0.785360142469201 0.996851066477098 0.65837081550851 0.996851066477098 0.996851066477098 0.996851066477098
Mccc2 ENSMUSG00000021646 0.103992409738451 0.311977229215354 0.946510695347679 0.990553335496302 0.990553335496302 0.990553335496302

Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pck1 ENSMUSG00000027513 0.805856984215314 0.929852653280503 0.689439771199441 0.929852653280503 0.929852653280503 0.929852653280503
Slc37a4 ENSMUSG00000032114 0.262588075504087 0.602208313494389 0.450186526729819 0.602208313494389 0.602208313494389 0.602208313494389
Fbp1 ENSMUSG00000069805 0.39478161017752 0.961937681860312 0.961937681860312 0.961937681860312 0.904074894953102 0.961937681860312
G6pc ENSMUSG00000078650 0.380159086257137 0.957566972324866 0.957566972324866 0.957566972324866 0.869391765394078 0.957566972324866

RAF activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Raf1 ENSMUSG00000000441 0.256261379347498 0.384392069021247 0.0478014302010051 0.143404290603015 0.477080496785617 0.477080496785617
Ppp1cb ENSMUSG00000014956 0.0062325033206576 0.0186975099619728 0.834212087971636 0.834212087971636 0.812618884512662 0.834212087971636
Brap ENSMUSG00000029458 0.987390481491559 0.987390481491559 0.469382307248243 0.704073460872365 0.461896202608299 0.704073460872365
Camk2d ENSMUSG00000053819 0.354940102208834 0.675495128730178 0.669717107139201 0.675495128730178 0.675495128730178 0.675495128730178

Collagen degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.481952482196683 0.722928723295024 0.134160370817291 0.402481112451874 0.831192438386663 0.831192438386663
Col6a2 ENSMUSG00000020241 0.365364134419754 0.684255641047139 0.50181032977184 0.684255641047139 0.684255641047139 0.684255641047139
Ctsl ENSMUSG00000021477 0.646894286663178 0.849749697770894 0.849749697770894 0.849749697770894 0.511994286915863 0.849749697770894
Col5a1 ENSMUSG00000026837 0.558851107387239 0.558851107387239 0.527391726030112 0.558851107387239 0.469747348316395 0.558851107387239
Furin ENSMUSG00000030530 0.946485401378501 0.946485401378501 0.326772422754962 0.771464310115938 0.514309540077292 0.771464310115938

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HDL remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoe ENSMUSG00000002985 0.583050276443025 0.855916433365217 0.855916433365217 0.855916433365217 0.701787306597725 0.855916433365217
Lcat ENSMUSG00000035237 0.690097759218862 0.690097759218862 0.62707227946314 0.690097759218862 0.669711721718957 0.690097759218862

Mitochondrial translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl21 ENSMUSG00000024829 0.2746175155773 0.532612751098105 0.532612751098105 0.532612751098105 0.419834758095859 0.532612751098105
Mrpl9 ENSMUSG00000028140 0.871436646554125 0.871436646554125 0.45722225681423 0.86561649449672 0.577077662997813 0.86561649449672
Mrpl54 ENSMUSG00000034932 0.137255687291676 0.205883530937514 0.00785432147831896 0.0235629644349569 0.687079518881331 0.687079518881331

Mitochondrial translation elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl21 ENSMUSG00000024829 0.2746175155773 0.532612751098105 0.532612751098105 0.532612751098105 0.419834758095859 0.532612751098105
Mrpl9 ENSMUSG00000028140 0.871436646554125 0.871436646554125 0.45722225681423 0.86561649449672 0.577077662997813 0.86561649449672
Mrpl54 ENSMUSG00000034932 0.137255687291676 0.205883530937514 0.00785432147831896 0.0235629644349569 0.687079518881331 0.687079518881331

Mitochondrial translation termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl21 ENSMUSG00000024829 0.2746175155773 0.532612751098105 0.532612751098105 0.532612751098105 0.419834758095859 0.532612751098105
Mrpl9 ENSMUSG00000028140 0.871436646554125 0.871436646554125 0.45722225681423 0.86561649449672 0.577077662997813 0.86561649449672
Mrpl54 ENSMUSG00000034932 0.137255687291676 0.205883530937514 0.00785432147831896 0.0235629644349569 0.687079518881331 0.687079518881331

Plasma lipoprotein remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoe ENSMUSG00000002985 0.583050276443025 0.855916433365217 0.855916433365217 0.855916433365217 0.701787306597725 0.855916433365217
Lcat ENSMUSG00000035237 0.690097759218862 0.690097759218862 0.62707227946314 0.690097759218862 0.669711721718957 0.690097759218862

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MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mef2c ENSMUSG00000005583 0.908876435323342 0.968519418679268 0.968519418679268 0.968519418679268 0.946510444910997 0.968519418679268
Cacnb1 ENSMUSG00000020882 0.722374192389518 0.981105775567252 0.522278916524063 0.981105775567252 0.981105775567252 0.981105775567252
Tgfb3 ENSMUSG00000021253 0.693012644581321 0.82200761564622 0.82200761564622 0.82200761564622 0.666967517008582 0.82200761564622
Ppp3cb ENSMUSG00000021816 0.974813316679948 0.974813316679948 0.535245794629393 0.974813316679948 0.865233500502656 0.974813316679948
Nr4a1 ENSMUSG00000023034 0.168196364752404 0.504589094257212 0.862111953725074 0.862111953725074 0.825056945309538 0.862111953725074
Rps6ka2 ENSMUSG00000023809 0.643780647383436 0.905629081925163 0.41341380005534 0.905629081925163 0.905629081925163 0.905629081925163
Jun ENSMUSG00000052684 0.152750691525194 0.458252074575582 0.393360898689608 0.509540121921587 0.509540121921587 0.509540121921587
Ppm1b ENSMUSG00000061130 0.965366767637531 0.965366767637531 0.00597638372292395 0.0179291511687718 0.908840967548332 0.965366767637531
Hspa1b ENSMUSG00000090877 0.0026729800077234 0.00801894002317021 0.222567442434517 0.333851163651776 0.669759347505814 0.669759347505814
Hspa1a ENSMUSG00000091971 0.0856036622485806 0.256810986745742 0.195179002835391 0.292768504253086 0.89944355312462 0.89944355312462

Cellular responses to external stimuli

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd2 ENSMUSG00000006998 0.0973761881761475 0.146064282264221 0.0520307721303682 0.146064282264221 0.244807205569705 0.244807205569705
Akt1s1 ENSMUSG00000011096 0.66388048491356 0.66388048491356 0.0133377754367031 0.0400133263101094 0.208128925657531 0.312193388486297
Ube2d1 ENSMUSG00000019927 0.415596910743107 0.871437628665942 0.761151419374494 0.871437628665942 0.871437628665942 0.871437628665942
Rps6ka2 ENSMUSG00000023809 0.643780647383436 0.905629081925163 0.41341380005534 0.905629081925163 0.905629081925163 0.905629081925163
Hspa5 ENSMUSG00000026864 0.0059930051622136 0.0179790154866408 0.184715061679808 0.277072592519711 0.530049638170799 0.530049638170799
Anapc5 ENSMUSG00000029472 0.411099282260985 0.616648923391477 0.124089360915384 0.372268082746153 0.725347712923866 0.725347712923866
Hif1an ENSMUSG00000036450 0.26798638692514 0.401979580387709 0.120123593937674 0.360370781813021 0.993701735271515 0.993701735271515
Psmd7 ENSMUSG00000039067 0.577676345551118 0.977946776558736 0.977946776558736 0.977946776558736 0.915083017427062 0.977946776558736
Hist1h2be ENSMUSG00000047246 0.618728438944353 0.618728438944353 0.130952584700433 0.3928577541013 0.300179650565374 0.450269475848061
Jun ENSMUSG00000052684 0.152750691525194 0.458252074575582 0.393360898689608 0.509540121921587 0.509540121921587 0.509540121921587
l7Rn6 ENSMUSG00000062797 0.408726920191643 0.613090380287464 0.209112140245723 0.613090380287464 0.638166181962613 0.638166181962613
Hspa1b ENSMUSG00000090877 0.0026729800077234 0.00801894002317021 0.222567442434517 0.333851163651776 0.669759347505814 0.669759347505814
Hspa1a ENSMUSG00000091971 0.0856036622485806 0.256810986745742 0.195179002835391 0.292768504253086 0.89944355312462 0.89944355312462

Cellular responses to stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd2 ENSMUSG00000006998 0.0973761881761475 0.146064282264221 0.0520307721303682 0.146064282264221 0.244807205569705 0.244807205569705
Akt1s1 ENSMUSG00000011096 0.66388048491356 0.66388048491356 0.0133377754367031 0.0400133263101094 0.208128925657531 0.312193388486297
Ube2d1 ENSMUSG00000019927 0.415596910743107 0.871437628665942 0.761151419374494 0.871437628665942 0.871437628665942 0.871437628665942
Rps6ka2 ENSMUSG00000023809 0.643780647383436 0.905629081925163 0.41341380005534 0.905629081925163 0.905629081925163 0.905629081925163
Hspa5 ENSMUSG00000026864 0.0059930051622136 0.0179790154866408 0.184715061679808 0.277072592519711 0.530049638170799 0.530049638170799
Anapc5 ENSMUSG00000029472 0.411099282260985 0.616648923391477 0.124089360915384 0.372268082746153 0.725347712923866 0.725347712923866
Hif1an ENSMUSG00000036450 0.26798638692514 0.401979580387709 0.120123593937674 0.360370781813021 0.993701735271515 0.993701735271515
Psmd7 ENSMUSG00000039067 0.577676345551118 0.977946776558736 0.977946776558736 0.977946776558736 0.915083017427062 0.977946776558736
Hist1h2be ENSMUSG00000047246 0.618728438944353 0.618728438944353 0.130952584700433 0.3928577541013 0.300179650565374 0.450269475848061
Jun ENSMUSG00000052684 0.152750691525194 0.458252074575582 0.393360898689608 0.509540121921587 0.509540121921587 0.509540121921587
l7Rn6 ENSMUSG00000062797 0.408726920191643 0.613090380287464 0.209112140245723 0.613090380287464 0.638166181962613 0.638166181962613
Hspa1b ENSMUSG00000090877 0.0026729800077234 0.00801894002317021 0.222567442434517 0.333851163651776 0.669759347505814 0.669759347505814
Hspa1a ENSMUSG00000091971 0.0856036622485806 0.256810986745742 0.195179002835391 0.292768504253086 0.89944355312462 0.89944355312462

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Spliceosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zmat2 ENSMUSG00000001383 0.424801126147108 0.637201689220662 0.357060935338281 0.637201689220662 0.834301514546456 0.834301514546456
Sf3a1 ENSMUSG00000002129 0.840438875170834 0.840438875170834 0.728300208308162 0.840438875170834 0.429243825447866 0.840438875170834
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Puf60 ENSMUSG00000002524 0.122126688897098 0.183190033345647 0.0473430856036172 0.142029256810851 0.53779597419782 0.53779597419782
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Cwc15 ENSMUSG00000004096 0.572269538520786 0.865240266985103 0.684298391674831 0.865240266985103 0.865240266985103 0.865240266985103
Bcas2 ENSMUSG00000005687 0.862076641749625 0.886958979907288 0.365312252212635 0.886958979907288 0.886958979907288 0.886958979907288
Prpf31 ENSMUSG00000008373 0.927669343869935 0.927669343869935 0.737204864427204 0.927669343869935 0.36741760703245 0.927669343869935
Rbm25 ENSMUSG00000010608 0.91827259821991 0.91827259821991 0.357093030007673 0.91827259821991 0.865243158078711 0.91827259821991
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Prpf3 ENSMUSG00000015748 0.887020085974762 0.887020085974762 0.803632537244706 0.887020085974762 0.627217570846182 0.887020085974762
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Sf3a2 ENSMUSG00000020211 0.698837728699018 0.815825102271188 0.68138216696554 0.815825102271188 0.815825102271188 0.815825102271188
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Ddx5 ENSMUSG00000020719 0.182046827679558 0.546140483038674 0.722367235103944 0.722367235103944 0.402107233833588 0.603160850750382
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Snw1 ENSMUSG00000021039 0.641262366426133 0.93708521614656 0.93708521614656 0.93708521614656 0.937083162009856 0.93708521614656
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Ddx46 ENSMUSG00000021500 0.136232818526581 0.408698455579741 0.42249855869066 0.63374783803599 0.905713436224748 0.905713436224748
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Acin1 ENSMUSG00000022185 0.749186273471211 0.880790475838231 0.880790475838231 0.880790475838231 0.849749714347201 0.880790475838231
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Cdc5l ENSMUSG00000023932 0.908822319977401 0.908822319977401 0.218320367929368 0.654961103788104 0.55070490413027 0.826057356195404
Srsf7 ENSMUSG00000024097 0.815871983280938 0.968520834299713 0.968520834299713 0.968520834299713 0.74618982782286 0.968520834299713
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Tcerg1 ENSMUSG00000024498 0.632855938009255 0.949283907013883 0.984254594040644 0.984254594040644 0.472111637466352 0.949283907013883
Rbm22 ENSMUSG00000024604 0.558919808180084 0.678487645353992 0.678487645353992 0.678487645353992 0.672727756407916 0.678487645353992
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Smndc1 ENSMUSG00000025024 0.965367521438985 0.965367521438985 0.26634545215952 0.799036356478559 0.821988383582378 0.965367521438985
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Sf3b1 ENSMUSG00000025982 0.734206035545172 0.734206035545172 0.621641114878589 0.734206035545172 0.658301984575608 0.734206035545172
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Ctnnbl1 ENSMUSG00000027649 0.658377821420181 0.782320636449417 0.782320636449417 0.782320636449417 0.635670240395242 0.782320636449417
Plrg1 ENSMUSG00000027998 0.68140120643685 0.68140120643685 0.486892343577072 0.68140120643685 0.477018689801654 0.68140120643685
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Srsf10 ENSMUSG00000028676 0.233674912956602 0.350512369434903 0.222888941141909 0.350512369434903 0.918270725038635 0.918270725038635
Sf3a3 ENSMUSG00000028902 0.933947680963532 0.933947680963532 0.87455809977212 0.933947680963532 0.519685402329841 0.933947680963532
Srsf4 ENSMUSG00000028911 0.417471225485942 0.945069432982301 0.630046288654867 0.945069432982301 0.968494950639536 0.968494950639536
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Tra2a ENSMUSG00000029817 0.348844468764241 0.84636412252459 0.871450949003191 0.871450949003191 0.564242748349727 0.84636412252459
Wbp11 ENSMUSG00000030216 0.859032843384184 0.859032843384184 0.566928581651813 0.859032843384184 0.719432498480505 0.859032843384184
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Snrpa1 ENSMUSG00000030512 0.269803315688056 0.404704973532084 0.0872801468469727 0.261840440540918 0.585829879420865 0.585829879420865
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Rbmx ENSMUSG00000031134 0.770223509907707 0.797521743547901 0.540454462581473 0.797521743547901 0.797521743547901 0.797521743547901
Pqbp1 ENSMUSG00000031157 0.666965418978755 0.719418000318808 0.0858192421217162 0.257457726365149 0.719418000318808 0.719418000318808
U2surp ENSMUSG00000032407 0.382391809326972 0.704648147768288 0.469765431845525 0.704648147768288 0.737208398499227 0.737208398499227
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
Dhx8 ENSMUSG00000034931 0.591206076039759 0.743193708028155 0.261276552998834 0.743193708028155 0.743193708028155 0.743193708028155
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Rbmxl1 ENSMUSG00000037070 0.216947576817546 0.535655779262514 0.357103852841676 0.535655779262514 0.652665364959371 0.652665364959371
Rbm17 ENSMUSG00000037197 0.949640762876706 0.949640762876706 0.684204858403164 0.949640762876706 0.641282419372059 0.949640762876706
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Sart1 ENSMUSG00000039148 0.255682116626992 0.383523174940487 0.150285264886121 0.383523174940487 0.846527772540081 0.846527772540081
Prpf18 ENSMUSG00000039449 0.129090582401795 0.387271747205386 0.855931138206339 0.95279349626811 0.95279349626811 0.95279349626811
Hnrnpu ENSMUSG00000039630 0.545644981217212 0.871449753757413 0.755143033014401 0.871449753757413 0.871449753757413 0.871449753757413
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Cherp ENSMUSG00000052488 0.797473880624064 0.949637976384499 0.621651399041408 0.949637976384499 0.949637976384499 0.949637976384499
Usp39 ENSMUSG00000056305 0.868237627224644 0.868237627224644 0.501875065011385 0.868237627224644 0.60474327807067 0.868237627224644
Hnrnpa3 ENSMUSG00000059005 0.105636484960633 0.316909454881898 0.81888866547801 0.921391871133013 0.921391871133013 0.921391871133013
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Snrpa ENSMUSG00000061479 0.534605497823689 0.555609483286124 0.170606409808356 0.511819229425067 0.555609483286124 0.555609483286124
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Snrnp70 ENSMUSG00000063511 0.524782402817906 0.912009745810262 0.912009745810262 0.912009745810262 0.855890115741388 0.912009745810262
Prpf38a ENSMUSG00000063800 0.921406595137766 0.990553841719651 0.380312342168521 0.990553841719651 0.990553841719651 0.990553841719651
Prpf4 ENSMUSG00000066148 0.828134400170103 0.828134400170103 0.812805235354818 0.828134400170103 0.509420357929062 0.828134400170103
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

RNA transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fmr1 ENSMUSG00000000838 0.542950018934397 0.542950018934397 0.481953805599263 0.542950018934397 0.375966137482608 0.542950018934397
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Eif2b5 ENSMUSG00000003235 0.0828391510582416 0.124258726587362 0.000894330731870369 0.00268299219561111 0.834234604248986 0.834234604248986
Eif2b2 ENSMUSG00000004788 0.865179764697839 0.865179764697839 0.319064362596573 0.481394889195354 0.320929926130236 0.481394889195354
Eif4g2 ENSMUSG00000005610 0.219898859108052 0.329848288662078 0.104826772476068 0.314480317428203 0.834313220534776 0.834313220534776
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Phax ENSMUSG00000008301 0.593994621681469 0.890991932522203 0.299988765429107 0.890991932522203 0.908834658280149 0.908834658280149
Nxf2 ENSMUSG00000009941 0.786978026679402 0.786978026679402 0.372444347651897 0.786978026679402 0.627597529784779 0.786978026679402
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Trnt1 ENSMUSG00000013736 0.320991484892554 0.647486917846728 0.431657945231152 0.647486917846728 0.72826355961016 0.72826355961016
Ddx19a ENSMUSG00000015023 0.290913817183677 0.436370725775516 0.110077349174795 0.330232047524386 0.83736745490414 0.83736745490414
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Eif3d ENSMUSG00000016554 0.0980391239285879 0.147058685892882 0.00508232624133938 0.0152469787240181 0.292704381368172 0.292704381368172
Fxr2 ENSMUSG00000018765 0.987401900478901 0.987401900478901 0.629978551080718 0.987401900478901 0.93706620945569 0.987401900478901
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Elac2 ENSMUSG00000020549 0.227295036782512 0.340942555173767 0.00738133170224313 0.0221439951067294 0.949636223354006 0.949636223354006
Sumo2 ENSMUSG00000020738 0.0608513759754348 0.182554127926304 0.553397465540346 0.621508553548806 0.621508553548806 0.621508553548806
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Pnn ENSMUSG00000020994 0.336682305939362 0.505023458909043 0.282028800455868 0.505023458909043 0.949646137926776 0.949646137926776
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Smn1 ENSMUSG00000021645 0.326871571824232 0.809722038047398 0.800560045965864 0.809722038047398 0.809722038047398 0.809722038047398
Sap18 ENSMUSG00000021963 0.550975093469159 0.550975093469159 0.287412154297856 0.550975093469159 0.42943044523394 0.550975093469159
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Acin1 ENSMUSG00000022185 0.749186273471211 0.880790475838231 0.880790475838231 0.880790475838231 0.849749714347201 0.880790475838231
Pop1 ENSMUSG00000022325 0.550930964020102 0.894951498773524 0.993701690259314 0.993701690259314 0.596634332515683 0.894951498773524
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Senp2 ENSMUSG00000022855 0.318959073507393 0.523070923993142 0.348713949328761 0.523070923993142 0.924493561362545 0.924493561362545
Eif4a2 ENSMUSG00000022884 0.776262606175218 0.794463575615136 0.509527671271441 0.794463575615136 0.794463575615136 0.794463575615136
Prmt5 ENSMUSG00000023110 0.763817687292467 0.763817687292467 0.367274907132652 0.763817687292467 0.74871598013116 0.763817687292467
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Clns1a ENSMUSG00000025439 0.509496895673322 0.509496895673322 0.143643215216752 0.430929645650255 0.422347461892208 0.509496895673322
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Eif5b ENSMUSG00000026083 0.106150985849222 0.318452957547666 0.675309140583142 0.782075706286792 0.782075706286792 0.782075706286792
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ddx20 ENSMUSG00000027905 0.859038138942191 0.962224450626547 0.529990757346025 0.962224450626547 0.962224450626547 0.962224450626547
Tgs1 ENSMUSG00000028233 0.202445619281456 0.607336857844367 0.681406823438836 0.722389056632982 0.722389056632982 0.722389056632982
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Eif2b3 ENSMUSG00000028683 0.930808259081165 0.930808259081165 0.871435650185804 0.930808259081165 0.455204549223561 0.930808259081165
Eif4g3 ENSMUSG00000028760 0.491524838477935 0.868316595934551 0.868316595934551 0.868316595934551 0.719196316284958 0.868316595934551
Srrm1 ENSMUSG00000028809 0.644098976290405 0.966148464435608 0.489382318541294 0.966148464435608 0.993701619222471 0.993701619222471
Pop7 ENSMUSG00000029715 0.033955668492766 0.050933502739149 0.00447235388694376 0.0134170616608313 0.243186589222412 0.243186589222412
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Strap ENSMUSG00000030224 0.464704066800854 0.697056100201281 0.155017403726981 0.465052211180942 0.815795007658257 0.815795007658257
Pop4 ENSMUSG00000030423 0.262959296901949 0.719444773635942 0.687184134716508 0.719444773635942 0.719444773635942 0.719444773635942
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Eif3c ENSMUSG00000030738 0.545414817842599 0.818122226763899 0.821959523795508 0.821959523795508 0.390875201608029 0.818122226763899
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Ddx19b ENSMUSG00000033658 0.537754862990056 0.746164533632793 0.746164533632793 0.746164533632793 0.593904566158944 0.746164533632793
Thoc5 ENSMUSG00000034274 0.13901087025118 0.208516305376771 0.133130347775632 0.208516305376771 0.496336589153104 0.496336589153104
Xpot ENSMUSG00000034667 0.797511766607 0.8158362955628 0.196927420176064 0.590782260528193 0.8158362955628 0.8158362955628
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Eif2s3x ENSMUSG00000035150 0.195519148289058 0.376945323539439 0.251296882359626 0.376945323539439 0.915138462344492 0.915138462344492
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Elac1 ENSMUSG00000036941 0.615996274515172 0.923994411772758 0.981108473338401 0.981108473338401 0.474599871898973 0.923994411772758
Gemin5 ENSMUSG00000037275 0.35498753165118 0.53248129747677 0.0619870721452988 0.185961216435896 0.791428611405528 0.791428611405528
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Upf3a ENSMUSG00000038398 0.868307354029982 0.868307354029982 0.806682984557619 0.868307354029982 0.537758592553213 0.868307354029982
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Gemin8 ENSMUSG00000040621 0.256037057548284 0.768111172644851 0.588307079872917 0.882460619809375 0.899487888803449 0.899487888803449
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Upf2 ENSMUSG00000043241 0.344813571752927 0.862136435003613 0.862136435003613 0.862136435003613 0.849735622506626 0.862136435003613
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Nupl2 ENSMUSG00000048439 0.98110595489204 0.98110595489204 0.722301174321265 0.98110595489204 0.728229084064878 0.98110595489204
Gemin4 ENSMUSG00000049396 0.728280763310707 0.728280763310707 0.399829192861332 0.599743789291998 0.198256909157096 0.594770727471287
Rpp38 ENSMUSG00000049950 0.687207765564406 0.687207765564406 0.596691132650808 0.687207765564406 0.669784975628704 0.687207765564406
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Pabpc1l ENSMUSG00000054582 0.34605204862127 0.878176209509401 0.965321557945143 0.965321557945143 0.585450806339601 0.878176209509401
Snupn ENSMUSG00000055334 0.448132247942238 0.752823647500484 0.50188243166699 0.752823647500484 0.9590809387123 0.9590809387123
Upf1 ENSMUSG00000058301 0.454990649563274 0.682485974344911 0.244773325539504 0.682485974344911 0.949621956320562 0.949621956320562
Pop5 ENSMUSG00000060152 0.0671949029979054 0.201584708993716 0.216937100688497 0.325405651032745 0.797510992281636 0.797510992281636
Nup98 ENSMUSG00000063550 0.361248635446065 0.890135959497788 0.890135959497788 0.890135959497788 0.740196224673654 0.890135959497788
Wibg ENSMUSG00000064030 0.431679286470194 0.927670382913582 0.84046913157975 0.927670382913582 0.927670382913582 0.927670382913582
Xpo5 ENSMUSG00000067150 0.8963483187472 0.8963483187472 0.522300267910383 0.78712665060481 0.524751100403207 0.78712665060481
Eif2s3y ENSMUSG00000069049 0.371727567925054 0.55759135188758 0.127082922536163 0.381248767608488 0.821981580506621 0.821981580506621
Eif3g ENSMUSG00000070319 0.146988948050685 0.220483422076027 0.0630237512779181 0.189071253833754 0.749115647096656 0.749115647096656
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
Rasl2-9 ENSMUSG00000083649 0.24756818392405 0.513203260175477 0.342135506783651 0.513203260175477 0.849660421146472 0.849660421146472

mRNA surveillance pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Smg5 ENSMUSG00000001415 0.415483851189053 0.623225776783579 0.233626583305425 0.623225776783579 0.791356325064641 0.791356325064641
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Nxf2 ENSMUSG00000009941 0.786978026679402 0.786978026679402 0.372444347651897 0.786978026679402 0.627597529784779 0.786978026679402
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Ddx19a ENSMUSG00000015023 0.290913817183677 0.436370725775516 0.110077349174795 0.330232047524386 0.83736745490414 0.83736745490414
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Wdr82 ENSMUSG00000020257 0.89634843389063 0.89634843389063 0.506998423287303 0.89634843389063 0.658277302596155 0.89634843389063
Papolg ENSMUSG00000020273 0.254589266575845 0.381883899863768 0.111818666850514 0.335456000551541 0.743170709671549 0.743170709671549
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Pnn ENSMUSG00000020994 0.336682305939362 0.505023458909043 0.282028800455868 0.505023458909043 0.949646137926776 0.949646137926776
Ppp2r3c ENSMUSG00000021022 0.545632448057358 0.818448672086036 0.29469936421847 0.818448672086036 0.93393928372919 0.93393928372919
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Sap18 ENSMUSG00000021963 0.550975093469159 0.550975093469159 0.287412154297856 0.550975093469159 0.42943044523394 0.550975093469159
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Acin1 ENSMUSG00000022185 0.749186273471211 0.880790475838231 0.880790475838231 0.880790475838231 0.849749714347201 0.880790475838231
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Srrm1 ENSMUSG00000028809 0.644098976290405 0.966148464435608 0.489382318541294 0.966148464435608 0.993701619222471 0.993701619222471
Ssu72 ENSMUSG00000029038 0.136242829605009 0.204364244407513 0.0504278103517965 0.151283431055389 0.743144881051361 0.743144881051361
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Smg1 ENSMUSG00000030655 0.472068853116066 0.80672069669531 0.537813797796873 0.80672069669531 0.825014254504631 0.825014254504631
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Ddx19b ENSMUSG00000033658 0.537754862990056 0.746164533632793 0.746164533632793 0.746164533632793 0.593904566158944 0.746164533632793
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Smg6 ENSMUSG00000038290 0.828114065290397 0.883890839950755 0.713539549054289 0.883890839950755 0.883890839950755 0.883890839950755
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Upf3a ENSMUSG00000038398 0.868307354029982 0.868307354029982 0.806682984557619 0.868307354029982 0.537758592553213 0.868307354029982
Ppp1ca ENSMUSG00000040385 0.146984170341655 0.220476255512483 0.0121365677036429 0.0364097031109288 0.550760247056706 0.550760247056706
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Pelo ENSMUSG00000042275 0.152733565022592 0.229100347533888 0.00270245217433143 0.00810735652299428 0.655503642806212 0.655503642806212
Smg7 ENSMUSG00000042772 0.30382898679522 0.911486960385659 0.930810925390078 0.930810925390078 0.930788722436065 0.930810925390078
Upf2 ENSMUSG00000043241 0.344813571752927 0.862136435003613 0.862136435003613 0.862136435003613 0.849735622506626 0.862136435003613
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Pabpc1l ENSMUSG00000054582 0.34605204862127 0.878176209509401 0.965321557945143 0.965321557945143 0.585450806339601 0.878176209509401
Cpsf6 ENSMUSG00000055531 0.65837749972958 0.837384360760915 0.837384360760915 0.837384360760915 0.713529914276932 0.837384360760915
Upf1 ENSMUSG00000058301 0.454990649563274 0.682485974344911 0.244773325539504 0.682485974344911 0.949621956320562 0.949621956320562
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Wibg ENSMUSG00000064030 0.431679286470194 0.927670382913582 0.84046913157975 0.927670382913582 0.927670382913582 0.927670382913582
Dazap1 ENSMUSG00000069565 0.292858570866924 0.8590294321058 0.719444653593317 0.8590294321058 0.8590294321058 0.8590294321058
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241

Ubiquitin mediated proteolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Rhobtb1 ENSMUSG00000019944 0.940116835372231 0.940116835372231 0.483972934063864 0.940116835372231 0.658089294075101 0.940116835372231
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Rhobtb2 ENSMUSG00000022075 0.627243469059781 0.78839774175095 0.610520795499542 0.78839774175095 0.78839774175095 0.78839774175095
Mgrn1 ENSMUSG00000022517 0.305815061085114 0.458722591627671 0.118351209981931 0.355053629945794 0.514627522318353 0.514627522318353
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Ppil2 ENSMUSG00000022771 0.577543641927057 0.577543641927057 0.532420035013502 0.577543641927057 0.402145855829321 0.577543641927057
Birc6 ENSMUSG00000024073 0.698676888791351 0.834210882462076 0.834210882462076 0.834210882462076 0.322980255022533 0.834210882462076
Cdc23 ENSMUSG00000024370 0.971648137380663 0.971648137380663 0.937075055671036 0.971648137380663 0.464625309234362 0.971648137380663
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Syvn1 ENSMUSG00000024807 0.0972022600460987 0.291606780138296 0.984256819430389 0.984256819430389 0.924508250242588 0.984256819430389
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Huwe1 ENSMUSG00000025261 0.669851622519722 0.962228686136411 0.962228686136411 0.962228686136411 0.604992885090226 0.962228686136411
Ube3a ENSMUSG00000025326 0.0100021217833753 0.030006365350126 0.0964484346882663 0.144672652032399 0.522158709680698 0.522158709680698
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Trip12 ENSMUSG00000026219 0.31527763384103 0.707623507301317 0.594013590497052 0.707623507301317 0.707623507301317 0.707623507301317
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Ubox5 ENSMUSG00000027300 0.289246626019819 0.433869939029728 0.752174358730662 0.752174358730662 0.170623956292642 0.433869939029728
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Ube2j1 ENSMUSG00000028277 0.472189545060989 0.96851806962253 0.96851806962253 0.96851806962253 0.719407192774666 0.96851806962253
Ube4b ENSMUSG00000028960 0.927659249123365 0.927659249123365 0.415671813311479 0.927659249123365 0.846622767795387 0.927659249123365
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Wwp2 ENSMUSG00000031930 0.321026297928993 0.321026297928993 0.109221743718641 0.321026297928993 0.302058762011907 0.321026297928993
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Fbxw8 ENSMUSG00000032867 0.0268126788080974 0.0402190182121461 0.000652959745291259 0.00195887923587378 0.452851229501988 0.452851229501988
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Mid1 ENSMUSG00000035299 0.974807191877227 0.974807191877227 0.101400498743987 0.304201496231962 0.809703024636313 0.974807191877227
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Siah1a ENSMUSG00000036840 0.713481603401334 0.766960237832609 0.601996199580706 0.766960237832609 0.766960237832609 0.766960237832609
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Ubr5 ENSMUSG00000037487 0.303862978176583 0.911588934529748 0.770216401764695 0.921384991846152 0.921384991846152 0.921384991846152
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Herc1 ENSMUSG00000038664 0.26109821284758 0.783294638542741 0.734165220730748 0.843515288270164 0.843515288270164 0.843515288270164
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Siah1b ENSMUSG00000040749 0.324771106968355 0.487156660452532 0.168048948708668 0.487156660452532 0.85588513080448 0.85588513080448
Wwp1 ENSMUSG00000041058 0.241489491015698 0.724468473047093 0.91826132991022 0.924534880356959 0.924534880356959 0.924534880356959
Ube2q1 ENSMUSG00000042572 0.59923306870678 0.874455317143018 0.450530094906324 0.874455317143018 0.874455317143018 0.874455317143018
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Ube4a ENSMUSG00000059890 0.0880020106174511 0.264006031852353 0.930788868983936 0.930788868983936 0.340650207372243 0.510975311058364
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Endocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Chmp1a ENSMUSG00000000743 0.0319483326409767 0.047922498961465 0.0146432781214625 0.0439298343643875 0.334656520287356 0.334656520287356
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Sh3gl1 ENSMUSG00000003200 0.734257170446249 0.734257170446249 0.404418970770285 0.606628456155427 0.397733389607841 0.606628456155427
Grk5 ENSMUSG00000003228 0.809709008637852 0.809709008637852 0.18603859416093 0.55811578248279 0.481914148190558 0.722871222285838
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Snf8 ENSMUSG00000006058 0.012863396720729 0.0192950950810935 0.00170650025632417 0.00511950076897252 0.824991011420563 0.824991011420563
Eps15l1 ENSMUSG00000006276 0.785251119050755 0.785251119050755 0.666888813786863 0.785251119050755 0.731161645452711 0.785251119050755
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Stambp ENSMUSG00000006906 0.684279337916864 0.684279337916864 0.681389164199228 0.684279337916864 0.574989725969528 0.684279337916864
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Git1 ENSMUSG00000011877 0.831216430645027 0.990553713062263 0.646967031206504 0.990553713062263 0.990553713062263 0.990553713062263
Tsg101 ENSMUSG00000014402 0.202477913474612 0.607433740423835 0.949645396642883 0.949645396642883 0.638440217186756 0.949645396642883
Zfyve20 ENSMUSG00000014550 0.675594907473703 0.758163822103712 0.758163822103712 0.758163822103712 0.67561226874794 0.758163822103712
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Zfyve27 ENSMUSG00000018820 0.519713651695142 0.779570477542713 0.96536311003534 0.96536311003534 0.49675286606198 0.779570477542713
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Snx3 ENSMUSG00000019804 0.98739982161536 0.98739982161536 0.00204816094420988 0.00614448283262965 0.740032537305376 0.98739982161536
Vta1 ENSMUSG00000019868 0.113723374771379 0.170585062157068 0.0473505327846662 0.142051598353999 0.788371093113175 0.788371093113175
Vps26a ENSMUSG00000020078 0.0226461030043265 0.0679383090129794 0.426884666182223 0.640326999273335 0.89631123412284 0.89631123412284
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Rufy1 ENSMUSG00000020375 0.740130266115853 0.949614807003285 0.669755040840901 0.949614807003285 0.949614807003285 0.949614807003285
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Zfyve16 ENSMUSG00000021706 0.424669911973703 0.849710977126219 0.638452523853179 0.849710977126219 0.849710977126219 0.849710977126219
E430025E21Rik ENSMUSG00000022350 0.424065068478242 0.484387469286486 0.484387469286486 0.484387469286486 0.466695485152038 0.484387469286486
Asap1 ENSMUSG00000022377 0.770211163763636 0.952793301476563 0.566942451615172 0.952793301476563 0.952793301476563 0.952793301476563
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Snx4 ENSMUSG00000022808 0.186009215633627 0.364671611152259 0.243114407434839 0.364671611152259 0.880772559105231 0.880772559105231
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Wash ENSMUSG00000024101 0.127970634396743 0.229123129065173 0.152748752710115 0.229123129065173 0.846634966020006 0.846634966020006
Fam21 ENSMUSG00000024104 0.779084869026502 0.918243704170313 0.918243704170313 0.918243704170313 0.660971666440276 0.918243704170313
Bin1 ENSMUSG00000024381 0.574927196052138 0.577653294094102 0.373888017702025 0.577653294094102 0.577653294094102 0.577653294094102
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Adrbk1 ENSMUSG00000024858 0.361229869200603 0.541844803800904 0.307695006136241 0.541844803800904 0.632826791918313 0.632826791918313
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Rnf41 ENSMUSG00000025373 0.918271852600076 0.918271852600076 0.825079431949656 0.918271852600076 0.716480625543547 0.918271852600076
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Smap1 ENSMUSG00000026155 0.501931311277436 0.984256258777349 0.687201510860506 0.984256258777349 0.984256258777349 0.984256258777349
Sh3glb2 ENSMUSG00000026860 0.455242638455681 0.62999523074248 0.613216240346766 0.62999523074248 0.62999523074248 0.62999523074248
Rab22a ENSMUSG00000027519 0.334492115394274 0.501738173091411 0.112535666740065 0.337607000220194 0.782169427079697 0.782169427079697
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Clta ENSMUSG00000028478 0.626800882680685 0.626800882680685 0.154929734580531 0.464789203741594 0.51934836378858 0.626800882680685
Eps15 ENSMUSG00000028552 0.23839979523243 0.715199385697289 0.527457391543817 0.791186087315726 0.86523993911738 0.86523993911738
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Fgfr2 ENSMUSG00000030849 0.489052549868025 0.907465482402088 0.959059315824168 0.959059315824168 0.604976988268059 0.907465482402088
2610002M06Rik ENSMUSG00000031242 0.509516782100346 0.940227468102068 0.877670188229835 0.940227468102068 0.940227468102068 0.940227468102068
Grk1 ENSMUSG00000031450 0.613111795615552 0.949642633387196 0.752097437775778 0.949642633387196 0.949642633387196 0.949642633387196
Vps35 ENSMUSG00000031696 0.113719590095891 0.341158770287674 0.319104328947984 0.47462991900775 0.47462991900775 0.47462991900775
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Snx1 ENSMUSG00000032382 0.564045115172256 0.818830897336289 0.818830897336289 0.818830897336289 0.684257410152455 0.818830897336289
Folr2 ENSMUSG00000032725 0.352129641827052 0.579309440947877 0.386206293965251 0.579309440947877 0.815833467125827 0.815833467125827
Smap2 ENSMUSG00000032870 0.477092323408172 0.715638485112258 0.404426702458855 0.715638485112258 0.937087214004604 0.937087214004604
Iqsec1 ENSMUSG00000034312 0.825076203631853 0.912006193905621 0.710586339795811 0.912006193905621 0.912006193905621 0.912006193905621
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
A230046K03Rik ENSMUSG00000034560 0.0316525133764236 0.0949575401292709 0.257905384669003 0.386858077003504 0.80666844592171 0.80666844592171
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Epn1 ENSMUSG00000035203 0.486916318044524 0.489403403033323 0.162096873199981 0.486290619599942 0.489403403033323 0.489403403033323
Eea1 ENSMUSG00000036499 0.00897735345572907 0.0269320603671872 0.0519013669945581 0.0778520504918372 0.85902223489798 0.85902223489798
Prkci ENSMUSG00000037643 0.553540357187378 0.99055225528109 0.99055225528109 0.99055225528109 0.815837729934611 0.99055225528109
Arap2 ENSMUSG00000037999 0.460068976514297 0.690103464771445 0.311409129430267 0.690103464771445 0.846651795130031 0.846651795130031
Wipf2 ENSMUSG00000038013 0.438729632472415 0.984256898514555 0.852842402789194 0.984256898514555 0.984256898514555 0.984256898514555
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Wwp1 ENSMUSG00000041058 0.241489491015698 0.724468473047093 0.91826132991022 0.924534880356959 0.924534880356959 0.924534880356959
Git2 ENSMUSG00000041890 0.764159983468941 0.764159983468941 0.607690584697949 0.764159983468941 0.213966028814276 0.641898086442827
Adrbk2 ENSMUSG00000042249 0.905704972160358 0.933950881520103 0.550754227659045 0.933950881520103 0.933950881520103 0.933950881520103
Snx12 ENSMUSG00000046032 0.6726305965563 0.728261605763111 0.092604416599998 0.277813249799994 0.728261605763111 0.728261605763111
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Vps37c ENSMUSG00000048832 0.899346352716889 0.899346352716889 0.307560750119503 0.899346352716889 0.701356730347006 0.899346352716889
Acap2 ENSMUSG00000049076 0.8220032577064 0.887020085974762 0.887020085974762 0.887020085974762 0.556256285457829 0.887020085974762
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Asap2 ENSMUSG00000052632 0.722326372802845 0.722326372802845 0.233676224726245 0.701028674178735 0.499328995561434 0.722326372802845
Grk4 ENSMUSG00000052783 0.933938076501482 0.933938076501482 0.716488473317298 0.933938076501482 0.658290932001407 0.933938076501482
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Arf2 ENSMUSG00000062421 0.933948983315106 0.94022758133894 0.94022758133894 0.94022758133894 0.746185886368294 0.94022758133894
Arfgef1 ENSMUSG00000067851 0.309412848540902 0.915128870248577 0.85594116165355 0.915128870248577 0.915128870248577 0.915128870248577
Arfgef2 ENSMUSG00000074582 0.859024821034593 0.859024821034593 0.171908608604465 0.515725825813396 0.610473558668627 0.859024821034593
Grk6 ENSMUSG00000074886 0.0902649105997454 0.262882351004862 0.262882351004862 0.262882351004862 0.246386360367993 0.262882351004862
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Eif2b5 ENSMUSG00000003235 0.0828391510582416 0.124258726587362 0.000894330731870369 0.00268299219561111 0.834234604248986 0.834234604248986
Zfp81 ENSMUSG00000003929 0.921398276173297 0.921398276173297 0.450420982394875 0.921398276173297 0.865197012496934 0.921398276173297
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Zfp324 ENSMUSG00000004500 0.927677083266821 0.927677083266821 0.734248202546478 0.927677083266821 0.716448379206918 0.927677083266821
Eif2b2 ENSMUSG00000004788 0.865179764697839 0.865179764697839 0.319064362596573 0.481394889195354 0.320929926130236 0.481394889195354
Srpk1 ENSMUSG00000004865 0.556236552709774 0.887010161258316 0.883876546553367 0.887010161258316 0.887010161258316 0.887010161258316
Eif2ak4 ENSMUSG00000005102 0.577681151008942 0.767204874273108 0.767204874273108 0.767204874273108 0.652670875836168 0.767204874273108
Bcl2l1 ENSMUSG00000007659 0.746191168970411 0.874557446877584 0.153856089929605 0.461568269788813 0.874557446877584 0.874557446877584
Pou2f2 ENSMUSG00000008496 0.78440929149125 0.799568301739656 0.713183887624394 0.799568301739656 0.799568301739656 0.799568301739656
Nxf2 ENSMUSG00000009941 0.786978026679402 0.786978026679402 0.372444347651897 0.786978026679402 0.627597529784779 0.786978026679402
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Zfp790 ENSMUSG00000011427 0.08725095874565 0.26175287623695 0.431745151093074 0.53262732242229 0.53262732242229 0.53262732242229
Zfp715 ENSMUSG00000012640 0.344777097099299 0.467299043406879 0.38031900870771 0.467299043406879 0.467299043406879 0.467299043406879
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Tbk1 ENSMUSG00000020115 0.384609190534306 0.915614726483065 0.955930879339086 0.955930879339086 0.610409817655377 0.915614726483065
Hcfc2 ENSMUSG00000020246 0.138338405400047 0.415015216200142 0.770225679630518 0.887001149054696 0.887001149054696 0.887001149054696
2810021J22Rik ENSMUSG00000020491 0.641318155987759 0.641318155987759 0.395552207210275 0.641318155987759 0.524854351922583 0.641318155987759
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Traf3 ENSMUSG00000021277 0.996851024285757 0.996851024285757 0.50951720821185 0.996851024285757 0.974813654004815 0.996851024285757
A530054K11Rik ENSMUSG00000021510 0.079401470788274 0.121062123721737 0.0807080824811581 0.121062123721737 0.725217096412423 0.725217096412423
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Srsf7 ENSMUSG00000024097 0.815871983280938 0.968520834299713 0.968520834299713 0.968520834299713 0.74618982782286 0.968520834299713
Zfp871 ENSMUSG00000024298 0.0398045680509124 0.119413704152737 0.0949677760423197 0.14245166406348 0.770224083518563 0.770224083518563
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Zfp282 ENSMUSG00000025821 0.86520171122549 0.974808871158847 0.809701439928137 0.974808871158847 0.974808871158847 0.974808871158847
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Eif2b3 ENSMUSG00000028683 0.930808259081165 0.930808259081165 0.871435650185804 0.930808259081165 0.455204549223561 0.930808259081165
Srsf4 ENSMUSG00000028911 0.417471225485942 0.945069432982301 0.630046288654867 0.945069432982301 0.968494950639536 0.968494950639536
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Zfp12 ENSMUSG00000029587 0.422465897532989 0.912008816289995 0.740157948518281 0.912008816289995 0.912008816289995 0.912008816289995
Eif2ak1 ENSMUSG00000029613 0.852075344279898 0.852075344279898 0.097338218823178 0.292014656469534 0.778081016442634 0.852075344279898
Zfp273 ENSMUSG00000030446 0.684144728971348 0.773114822827084 0.229003963566323 0.687011890698969 0.773114822827084 0.773114822827084
Zfp626 ENSMUSG00000030604 0.746171241161978 0.955937633582514 0.955937633582514 0.955937633582514 0.359155367155075 0.955937633582514
Zfp275 ENSMUSG00000031365 0.569439997978266 0.569439997978266 0.561465189584189 0.569439997978266 0.402127415130171 0.569439997978266
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Zfp90 ENSMUSG00000031907 0.883903287645641 0.883903287645641 0.704719387396106 0.883903287645641 0.543083039876083 0.883903287645641
Zfp949 ENSMUSG00000032425 0.687205349770811 0.984255617204306 0.984255617204306 0.984255617204306 0.785340685341192 0.984255617204306
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Zfp7 ENSMUSG00000033669 0.566857824211868 0.613250560469748 0.462500550411562 0.613250560469748 0.613250560469748 0.613250560469748
Zfp944 ENSMUSG00000033972 0.209644304089903 0.566914450263349 0.411112217202674 0.566914450263349 0.566914450263349 0.566914450263349
Zfp418 ENSMUSG00000034538 0.14268551345265 0.214028270178975 0.142652524867088 0.214028270178975 0.627237966620823 0.627237966620823
Zfp661 ENSMUSG00000034800 0.477089366826772 0.575003228483636 0.292885080548305 0.575003228483636 0.575003228483636 0.575003228483636
Ccl2 ENSMUSG00000035385 0.598218036397384 0.830987046359667 0.401124167843243 0.830987046359667 0.830987046359667 0.830987046359667
Zfp157 ENSMUSG00000036898 0.737229317287235 0.874542761003085 0.22739896474232 0.68219689422696 0.874542761003085 0.874542761003085
Zfp39 ENSMUSG00000037001 0.93708584005951 0.93708584005951 0.399975406059634 0.637169037361973 0.424779358241315 0.637169037361973
Zfp597 ENSMUSG00000039789 0.865238240128123 0.943369292277876 0.943369292277876 0.943369292277876 0.752172886334349 0.943369292277876
Ppp1ca ENSMUSG00000040385 0.146984170341655 0.220476255512483 0.0121365677036429 0.0364097031109288 0.550760247056706 0.550760247056706
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Zfp386 ENSMUSG00000042063 0.719407853271497 0.719407853271497 0.0173090693496571 0.0519272080489714 0.649794999527396 0.719407853271497
Zfp866 ENSMUSG00000043090 0.561575128126381 0.785363088640402 0.785363088640402 0.785363088640402 0.548342959530219 0.785363088640402
Zfp688 ENSMUSG00000045251 0.0510429928638419 0.153128978591526 0.472043217252454 0.708064825878682 0.86517801866064 0.86517801866064
Zfp956 ENSMUSG00000045466 0.113711288157872 0.341133864473616 0.887017066230547 0.887017066230547 0.317197108700309 0.475795663050463
Zfp84 ENSMUSG00000046185 0.326804139784684 0.84636124820161 0.933948078299297 0.933948078299297 0.564240832134407 0.84636124820161
Zfp689 ENSMUSG00000048921 0.746161823092674 0.746161823092674 0.646960744142472 0.746161823092674 0.519698243563037 0.746161823092674
Zfp61 ENSMUSG00000050605 0.728255393999416 0.80972891649625 0.296433823886353 0.80972891649625 0.80972891649625 0.80972891649625
Zfp623 ENSMUSG00000050846 0.588253428760559 0.908851959991809 0.868198213785425 0.908851959991809 0.908851959991809 0.908851959991809
Zfp169 ENSMUSG00000050954 0.225956461911946 0.338934692867919 0.151599034348063 0.338934692867919 0.9653745468202 0.9653745468202
Zfp961 ENSMUSG00000052446 0.313345469879295 0.51343843204474 0.342292288029827 0.51343843204474 0.537618763610479 0.537618763610479
Zfp212 ENSMUSG00000052763 0.0933273760001477 0.279982128000443 0.276778316078644 0.415167474117966 0.646917019555695 0.646917019555695
Zfp952 ENSMUSG00000053390 0.984257221868525 0.984257221868525 0.448158705547278 0.984257221868525 0.788397649478662 0.984257221868525
Zfp867 ENSMUSG00000054519 0.00135825115299108 0.00407475345897325 0.434055483426102 0.434055483426102 0.141618529549119 0.212427794323679
Zfp869 ENSMUSG00000054648 0.517171318474107 0.749172277505117 0.215457792309496 0.646373376928489 0.749172277505117 0.749172277505117
Zfp182 ENSMUSG00000054737 0.427126727517221 0.604952534092113 0.31146829070004 0.604952534092113 0.604952534092113 0.604952534092113
Zfp78 ENSMUSG00000055150 0.26627947686516 0.472921574890155 0.31528104992677 0.472921574890155 0.669832326835454 0.669832326835454
Zfp101 ENSMUSG00000055240 0.734262482213761 0.734262482213761 0.594012848288838 0.734262482213761 0.556278619594594 0.734262482213761
Zfp457 ENSMUSG00000055341 0.930746361961035 0.930746361961035 0.469074828413572 0.930746361961035 0.680944397078772 0.930746361961035
Zfp459 ENSMUSG00000055560 0.890135106257556 0.911994958053049 0.874544220095528 0.911994958053049 0.911994958053049 0.911994958053049
Zfp1 ENSMUSG00000055835 0.779242000222628 0.924521140114988 0.0957265253762001 0.2871795761286 0.924521140114988 0.924521140114988
Zfp709 ENSMUSG00000056019 0.797521765668082 0.797521765668082 0.443426304833404 0.797521765668082 0.791439214671057 0.797521765668082
Zfp658 ENSMUSG00000056592 0.228914595980664 0.529448402085402 0.352965601390268 0.529448402085402 0.740145018102158 0.740145018102158
Zfp180 ENSMUSG00000057101 0.635672883009121 0.716491563767633 0.50699756826521 0.716491563767633 0.716491563767633 0.716491563767633
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Zfp317 ENSMUSG00000057551 0.955937432081627 0.955937432081627 0.350911493675258 0.919893453908227 0.613262302605485 0.919893453908227
Zfp746 ENSMUSG00000057691 0.716416334129172 0.91511973774182 0.690105046205586 0.91511973774182 0.91511973774182 0.91511973774182
AA987161 ENSMUSG00000058093 0.0793791458962707 0.128650567916378 0.0857670452775856 0.128650567916378 0.921364124135029 0.921364124135029
Zfp68 ENSMUSG00000058291 0.455150050298807 0.68272507544821 0.081503883668268 0.244511651004804 0.971667019548324 0.971667019548324
Zfp85-rs1 ENSMUSG00000058331 0.591155010940586 0.886732516410878 0.38459913148321 0.886732516410878 0.965363543131173 0.965363543131173
Zfp420 ENSMUSG00000058402 0.155023950321555 0.465071850964665 0.56424187734588 0.56424187734588 0.371750809395157 0.557626214092735
Zfp958 ENSMUSG00000058748 0.489436579161014 0.734154868741521 0.195518847115919 0.586556541347758 0.968519098996606 0.968519098996606
Zfp708 ENSMUSG00000058883 0.0367812214259034 0.0551718321388551 0.0287646677345999 0.0551718321388551 0.815675210741152 0.815675210741152
Zfp933 ENSMUSG00000059423 0.273270236069557 0.819810708208671 0.905754737927032 0.987405359216788 0.987405359216788 0.987405359216788
Zfp426 ENSMUSG00000059475 0.219940486145568 0.545696630321519 0.545696630321519 0.545696630321519 0.524863157898077 0.545696630321519
Zfp874b ENSMUSG00000059839 0.0310173143234376 0.0930519429703127 0.42943013546867 0.644145203203005 0.794479238099772 0.794479238099772
Zfp930 ENSMUSG00000059897 0.361252345489859 0.540469855280646 0.199703551776161 0.540469855280646 0.540469855280646 0.540469855280646
Zfp74 ENSMUSG00000059975 0.74312652221704 0.846609686576337 0.846609686576337 0.846609686576337 0.610487324547613 0.846609686576337
2610008E11Rik ENSMUSG00000060301 0.937088587859688 0.990553726771907 0.173175304932738 0.519525914798214 0.990553726771907 0.990553726771907
Zfp937 ENSMUSG00000060336 0.50693038776156 0.52223685668885 0.371587959673858 0.52223685668885 0.52223685668885 0.52223685668885
Zfp868 ENSMUSG00000060427 0.965372618937206 0.965372618937206 0.302087966044594 0.906263898133781 0.773232937223261 0.965372618937206
Zfp266 ENSMUSG00000060510 0.109229409855348 0.163844114783023 0.0948823159651234 0.163844114783023 0.556169256281808 0.556169256281808
Zfp873 ENSMUSG00000061371 0.725355719425837 0.902625754780667 0.902625754780667 0.902625754780667 0.296514941101917 0.88954482330575
Zfp229 ENSMUSG00000061544 0.675617394576195 0.788380161701511 0.788380161701511 0.788380161701511 0.153832893418283 0.46149868025485
Rbak ENSMUSG00000061898 0.572255709186311 0.572255709186311 0.397706393491126 0.572255709186311 0.227495396189693 0.572255709186311
Zfp954 ENSMUSG00000062116 0.658369028217264 0.959082992771107 0.959081970344945 0.959082992771107 0.959082992771107 0.959082992771107
Zfp398 ENSMUSG00000062519 0.564185686622195 0.877651726266627 0.849742320769921 0.877651726266627 0.877651726266627 0.877651726266627
Zfp599 ENSMUSG00000062794 0.855895466407933 0.855895466407933 0.429223566958994 0.711806380537201 0.4745375870248 0.711806380537201
Zfp28 ENSMUSG00000062861 0.486832734119497 0.803632902387604 0.803632902387604 0.803632902387604 0.624360129581231 0.803632902387604
Zfp780b ENSMUSG00000063047 0.39107661533431 0.467333115705241 0.467333115705241 0.467333115705241 0.34277150669525 0.467333115705241
Zfp26 ENSMUSG00000063108 0.821974014101236 0.821974014101236 0.0821760522760048 0.246528156828014 0.78228040954523 0.821974014101236
Zfp947 ENSMUSG00000063383 0.905755209213926 0.905755209213926 0.840479500240255 0.905755209213926 0.71059986098015 0.905755209213926
Zfp773 ENSMUSG00000063535 0.369601125135033 0.899497679882541 0.695913921419629 0.899497679882541 0.899497679882541 0.899497679882541
Zfp617 ENSMUSG00000066880 0.268096534148183 0.402144801222275 0.108317010074898 0.324951030224694 0.583011859976807 0.583011859976807
Zfp760 ENSMUSG00000067928 0.48687582265191 0.548295288947333 0.522226293473166 0.548295288947333 0.548295288947333 0.548295288947333
Zfp948 ENSMUSG00000067931 0.0285453743051351 0.0856361229154051 0.195421754963501 0.293132632445251 0.937089239708422 0.937089239708422
Zfp160 ENSMUSG00000067942 0.924541399094157 0.924541399094157 0.249662670833093 0.748988012499278 0.610522750033069 0.915784125049603
Zfp442 ENSMUSG00000068130 0.334710899073492 0.502066348610238 0.178194264925847 0.502066348610238 0.537804113289125 0.537804113289125
Zfp120 ENSMUSG00000068134 0.828151554474058 0.828151554474058 0.445754607281558 0.828151554474058 0.825056118712257 0.828151554474058
Zfp619 ENSMUSG00000068959 0.737041831331752 0.737041831331752 0.390867555212956 0.586301332819434 0.350369680550889 0.586301332819434
Gm5595 ENSMUSG00000069727 0.150466132955774 0.225699199433661 0.0696380933388098 0.208914280016429 0.737238389965789 0.737238389965789
1700049G17Rik ENSMUSG00000070709 0.684297290588225 0.74319910385997 0.328836522252172 0.74319910385997 0.74319910385997 0.74319910385997
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Zfp71-rs1 ENSMUSG00000071281 0.320955744765794 0.43629926817455 0.252950895013197 0.43629926817455 0.43629926817455 0.43629926817455
Zfp58 ENSMUSG00000071291 0.106485465019645 0.319456395058934 0.275039255382156 0.412558883073233 0.858972197869106 0.858972197869106
Zfp777 ENSMUSG00000071477 0.689944449423662 0.788372062330914 0.788372062330914 0.788372062330914 0.746062404061836 0.788372062330914
Zfp951 ENSMUSG00000072774 0.852830657373344 0.852830657373344 0.0332933575677086 0.0998800727031258 0.411109598860533 0.616664398290799
Gm12258 ENSMUSG00000072915 0.545716970774066 0.607737255789502 0.607737255789502 0.607737255789502 0.399970500553649 0.607737255789502
Zfp788 ENSMUSG00000074165 0.501939249282704 0.752908873924056 0.20391558411582 0.61174675234746 0.849748106419898 0.849748106419898
Zfp94 ENSMUSG00000074282 0.395556967321084 0.604948942256054 0.604948942256054 0.604948942256054 0.43866682563663 0.604948942256054
5830428H23Rik ENSMUSG00000074733 0.613252782036663 0.613252782036663 0.128961433513013 0.364701914375926 0.24313460958395 0.364701914375926
AU041133 ENSMUSG00000078435 0.532559173816322 0.532559173816322 0.107365303535444 0.322095910606332 0.375840048285497 0.532559173816322
Gm13151 ENSMUSG00000078498 0.993543540726641 0.993543540726641 0.45263813903982 0.838316042200416 0.558877361466944 0.838316042200416
Zfp566 ENSMUSG00000078768 0.311349031679773 0.770198117090135 0.770181200504567 0.770198117090135 0.770198117090135 0.770198117090135
Gm14434 ENSMUSG00000078881 0.596648247476333 0.704689897319573 0.164449825007136 0.493349475021408 0.704689897319573 0.704689897319573
Gm4631 ENSMUSG00000078899 0.269727894986113 0.502123613723114 0.334749075815409 0.502123613723114 0.837378505197575 0.837378505197575
Zfp712 ENSMUSG00000090641 0.616025187199772 0.8158089350715 0.0980830921443612 0.294249276433084 0.8158089350715 0.8158089350715
Gm5141 ENSMUSG00000091183 0.728251981722718 0.785346672713238 0.785346672713238 0.785346672713238 0.529811219353198 0.785346672713238
Zfp963 ENSMUSG00000092260 0.149247241613784 0.447741724841352 0.984253468681904 0.984253468681904 0.943367928879089 0.984253468681904
Zfp141 ENSMUSG00000092416 0.262977285302008 0.583468896788912 0.388979264525942 0.583468896788912 0.794475603286245 0.794475603286245
Gm4767 ENSMUSG00000094076 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Gm3055 ENSMUSG00000094622 0.402074402044685 0.402074402044685 0.0265733695751973 0.079720108725592 0.235082437531107 0.352623656296661
Zfp870 ENSMUSG00000095325 0.80968410981223 0.80968410981223 0.422411415597203 0.633617123395805 0.296455215798333 0.633617123395805
Zfp748 ENSMUSG00000095432 0.29287279987543 0.45309017495156 0.302060116634373 0.45309017495156 0.569620779197383 0.569620779197383
Gm4944 ENSMUSG00000096433 0.321014965267144 0.481522447900716 0.269835056962084 0.481522447900716 0.564203243100495 0.564203243100495
Zfp960 ENSMUSG00000096696 0.782323385382656 0.782323385382656 0.10386320132676 0.31158960398028 0.564075420300437 0.782323385382656
Gm10778 ENSMUSG00000096856 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp850 ENSMUSG00000096916 0.0162413692250362 0.0487241076751085 0.109809256441679 0.164713884662518 0.289872922375917 0.289872922375917
Zfp87 ENSMUSG00000097333 0.307373830560574 0.461060745840861 0.0495595649496402 0.148678694848921 0.868301084753766 0.868301084753766
Zfp82 ENSMUSG00000098022 0.918250985155804 1 1 1 0.812779072974999 1

RNA degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Skiv2l2 ENSMUSG00000016018 0.119136042931793 0.357408128795379 0.238396318461405 0.357594477692107 0.877613080915908 0.877613080915908
Exosc10 ENSMUSG00000017264 0.749152646721473 0.749152646721473 0.378106677050551 0.567160015575827 0.31140300100266 0.567160015575827
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Parn ENSMUSG00000022685 0.469734430393029 0.809717827234914 0.809717827234914 0.809717827234914 0.574966136226258 0.809717827234914
Btg3 ENSMUSG00000022863 0.655480164753694 0.908874733329627 0.110091338289107 0.330274014867322 0.908874733329627 0.908874733329627
Hspa9 ENSMUSG00000024359 0.874372392628939 0.874372392628939 0.130956750318228 0.392870250954683 0.692572140526636 0.874372392628939
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Dhx36 ENSMUSG00000027770 0.915118944292855 0.915118944292855 0.893244625018978 0.915118944292855 0.773217933538163 0.915118944292855
Pan3 ENSMUSG00000029647 0.655456393746432 0.849722654511013 0.524801691324984 0.849722654511013 0.849722654511013 0.849722654511013
Mphosph6 ENSMUSG00000031843 0.522199300603304 0.783298950904956 0.268083439074963 0.783298950904956 0.840444590221339 0.840444590221339
Ddx6 ENSMUSG00000032097 0.404397194234859 0.752177062517396 0.752177062517396 0.752177062517396 0.652647416539278 0.752177062517396
Xrn1 ENSMUSG00000032410 0.160890735972028 0.352894754717987 0.235263169811991 0.352894754717987 0.627232733306543 0.627232733306543
Nudt16 ENSMUSG00000032565 0.162068456201106 0.243102684301659 0.112789676031758 0.243102684301659 0.868323679105672 0.868323679105672
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Ttc37 ENSMUSG00000033991 0.209479265727045 0.314218898590567 0.161957506810136 0.314218898590567 0.602092125220025 0.602092125220025
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Papd7 ENSMUSG00000034575 0.806682159308007 0.996851257020197 0.464913070771073 0.996851257020197 0.996851257020197 0.996851257020197
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Zcchc7 ENSMUSG00000035649 0.489253520798075 0.733880281197113 0.158512261908711 0.475536785726132 0.977951815130865 0.977951815130865
Edc4 ENSMUSG00000036270 0.447732033653221 0.671598050479831 0.90571021658287 0.90571021658287 0.382024560264176 0.671598050479831
Papd5 ENSMUSG00000036779 0.210920096288331 0.632760288864994 0.843450996221767 0.843450996221767 0.692838808982448 0.843450996221767
Tob1 ENSMUSG00000037573 0.303899891786918 0.46707635269382 0.311384235129213 0.46707635269382 0.797529905402938 0.797529905402938
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Edc3 ENSMUSG00000038957 0.296508606448352 0.590017516235972 0.393345010823981 0.590017516235972 0.701792729756973 0.701792729756973
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388
Skiv2l ENSMUSG00000040356 0.320818972045176 0.481228458067763 0.303842486320552 0.481228458067763 0.812719792582066 0.812719792582066
Dcp1b ENSMUSG00000041477 0.737228299731999 0.955937196174637 0.556281929705088 0.955937196174637 0.955937196174637 0.955937196174637
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Patl1 ENSMUSG00000046139 0.393283354429965 0.633716138428704 0.422477425619136 0.633716138428704 0.971664088103294 0.971664088103294
Pabpc1l ENSMUSG00000054582 0.34605204862127 0.878176209509401 0.965321557945143 0.965321557945143 0.585450806339601 0.878176209509401
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Eno1 ENSMUSG00000063524 0.564113347358687 0.564113347358687 0.242910138014227 0.538403804399347 0.358935869599564 0.538403804399347

Basal transcription factors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Taf6l ENSMUSG00000003680 0.23833905113215 0.357508576698225 0.0473271388907852 0.141981416672356 0.627198287996468 0.627198287996468
Gtf2h1 ENSMUSG00000006599 0.0864439700177123 0.259331910053137 0.354993782966202 0.532490674449303 0.764013716187645 0.764013716187645
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Gtf2ird1 ENSMUSG00000023079 0.192795021369328 0.578385064107984 0.427108519962076 0.640662779943114 0.79751464259488 0.79751464259488
Taf8 ENSMUSG00000023980 0.828124441516432 0.828124441516432 0.271482342300993 0.748921555648755 0.49928103709917 0.748921555648755
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Taf2 ENSMUSG00000037343 0.404084808090432 0.940750369966192 0.627166913310795 0.940750369966192 0.943324646646258 0.943324646646258
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Tbpl1 ENSMUSG00000071359 0.275013205568797 0.412519808353195 0.946502446975898 0.946502446975898 0.24312159998559 0.412519808353195

Autophagy - animal

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Eif2ak4 ENSMUSG00000005102 0.577681151008942 0.767204874273108 0.767204874273108 0.767204874273108 0.652670875836168 0.767204874273108
Bcl2l1 ENSMUSG00000007659 0.746191168970411 0.874557446877584 0.153856089929605 0.461568269788813 0.874557446877584 0.874557446877584
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Tbk1 ENSMUSG00000020115 0.384609190534306 0.915614726483065 0.955930879339086 0.955930879339086 0.610409817655377 0.915614726483065
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Atg2a ENSMUSG00000024773 0.463648979381158 1 0.874427498800855 1 1 1
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Rptor ENSMUSG00000025583 0.664108758918949 0.701783944724874 0.340784524476415 0.701783944724874 0.701783944724874 0.701783944724874
Rb1cc1 ENSMUSG00000025907 0.0208416219879959 0.0625248659639876 0.178061649430789 0.267092474146184 0.846568779833561 0.846568779833561
Atg4b ENSMUSG00000026280 0.940212228542754 0.940212228542754 0.0902738449647753 0.270821534894326 0.298282947773483 0.447424421660224
Atg16l1 ENSMUSG00000026289 0.918269688368391 0.918269688368391 0.828149419912083 0.918269688368391 0.725337615491778 0.918269688368391
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Supt20 ENSMUSG00000027751 0.681385127389826 0.681385127389826 0.527442478342905 0.681385127389826 0.605002244760935 0.681385127389826
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
3110043O21Rik ENSMUSG00000028300 0.397756156583701 0.75816834922066 0.63566284077118 0.75816834922066 0.75816834922066 0.75816834922066
Atg4c ENSMUSG00000028550 0.965373318266653 0.965373318266653 0.646988206219499 0.965373318266653 0.952795444050959 0.965373318266653
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Wipi2 ENSMUSG00000029578 0.504266733604144 0.504266733604144 0.165737192219274 0.497211576657822 0.431517931610113 0.504266733604144
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Atg12 ENSMUSG00000032905 0.399989119756591 0.943367739510359 0.743193874058818 0.943367739510359 0.943367739510359 0.943367739510359
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Mtmr3 ENSMUSG00000034354 0.380119349028901 0.570179023543351 0.256261486022692 0.570179023543351 0.672559498007883 0.672559498007883
Dapk3 ENSMUSG00000034974 0.646764905350157 0.803504160053688 0.0382676412972832 0.11480292389185 0.803504160053688 0.803504160053688
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
1700021K19Rik ENSMUSG00000035629 0.391113003034842 0.627233425963702 0.481991836889904 0.627233425963702 0.627233425963702 0.627233425963702
9430023L20Rik ENSMUSG00000037204 0.0584555665933076 0.175366699779923 0.927677413404358 0.927677413404358 0.767005890614081 0.927677413404358
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Ambra1 ENSMUSG00000040506 0.660903032875549 0.874473792120054 0.868253657118628 0.874473792120054 0.874473792120054 0.874473792120054
Atg2b ENSMUSG00000041341 0.90883639295229 0.965358294616816 0.607736332962354 0.965358294616816 0.965358294616816 0.965358294616816
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Wdr41 ENSMUSG00000042015 0.737214759469796 0.95279189048202 0.719432438451339 0.95279189048202 0.95279189048202 0.95279189048202
Atg16l2 ENSMUSG00000047767 0.902628870226528 0.902628870226528 0.46973770964634 0.70460656446951 0.452901533706054 0.70460656446951
Smcr8 ENSMUSG00000049323 0.298239334470285 0.661562185242772 0.678459563912507 0.678459563912507 0.441041456828515 0.661562185242772
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106

Cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Zbtb17 ENSMUSG00000006215 0.350653415165246 0.525980122747868 0.330729243975288 0.525980122747868 0.767173206519076 0.767173206519076
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Hdac2 ENSMUSG00000019777 0.764097451408013 0.993700732114544 0.862102361923653 0.993700732114544 0.993700732114544 0.993700732114544
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Cdc23 ENSMUSG00000024370 0.971648137380663 0.971648137380663 0.937075055671036 0.971648137380663 0.464625309234362 0.971648137380663
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mad2l2 ENSMUSG00000029003 0.0163341725967249 0.0490025177901746 0.211013925138425 0.316520887707637 0.794360760642728 0.794360760642728
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cdc7 ENSMUSG00000029283 0.905754675088245 0.937088160291987 0.937088160291987 0.937088160291987 0.758177847489751 0.937088160291987
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Orc6 ENSMUSG00000031697 0.849714245077774 0.849720664240127 0.849720664240127 0.849720664240127 0.669739549348859 0.849720664240127
Tfdp2 ENSMUSG00000032411 0.0899531488941501 0.26985944668245 0.440640131029761 0.660960196544641 0.924012775992792 0.924012775992792
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Cdkn2d ENSMUSG00000096472 0.246335950338178 0.411080637724506 0.411080637724506 0.411080637724506 0.402207804417436 0.411080637724506

Inositol phosphate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Inpp5k ENSMUSG00000006127 0.566857130340692 0.854429356932178 0.89010984134026 0.89010984134026 0.569619571288119 0.854429356932178
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr1 ENSMUSG00000015214 0.28209068750968 0.613378299339732 0.408918866226488 0.613378299339732 0.990553880737655 0.990553880737655
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Isyna1 ENSMUSG00000019139 0.313356098364675 0.470034147547012 0.0901096436336722 0.270328930901017 0.96849865774593 0.96849865774593
Plcd3 ENSMUSG00000020937 0.19690131712475 0.59070395137425 0.424821026116843 0.637231539175265 0.803629830827979 0.803629830827979
Ippk ENSMUSG00000021385 0.496886488781754 0.943358849667233 0.943358849667233 0.943358849667233 0.68139363815062 0.943358849667233
Mtmr6 ENSMUSG00000021987 0.113641206247705 0.340923618743115 0.384520718380111 0.576781077570167 0.987405339532972 0.987405339532972
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Minpp1 ENSMUSG00000024896 0.658348829880057 0.981099324919946 0.0113741869790523 0.034122560937157 0.981099324919946 0.981099324919946
Plce1 ENSMUSG00000024998 0.825043160749253 0.962222498862426 0.962222498862426 0.962222498862426 0.852794201063591 0.962222498862426
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Inpp1 ENSMUSG00000026102 0.806672191997436 0.806672191997436 0.501896590044763 0.764179279372299 0.509452852914866 0.764179279372299
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Inpp5b ENSMUSG00000028894 0.831196617340709 0.831196617340709 0.722292545166494 0.831196617340709 0.646912568962143 0.831196617340709
Cdipt ENSMUSG00000030682 0.632599618115493 0.632599618115493 0.0957536977912475 0.287261093373743 0.393067572338565 0.589601358507848
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Mtmr3 ENSMUSG00000034354 0.380119349028901 0.570179023543351 0.256261486022692 0.570179023543351 0.672559498007883 0.672559498007883
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Plch1 ENSMUSG00000036834 0.473799531632094 0.802247443141442 0.688225758265262 0.802247443141442 0.802247443141442 0.802247443141442
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965
Itpkb ENSMUSG00000038855 0.646948389636692 0.646948389636692 0.20385417619165 0.611562528574949 0.604962380872254 0.646948389636692
Pi4kb ENSMUSG00000038861 0.785002570027176 0.809512890262261 0.519502292050506 0.809512890262261 0.809512890262261 0.809512890262261
Itpk1 ENSMUSG00000057963 0.83737377730881 0.83737377730881 0.719396864399788 0.83737377730881 0.728283678868544 0.83737377730881

Nucleotide excision repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Gtf2h1 ENSMUSG00000006599 0.0864439700177123 0.259331910053137 0.354993782966202 0.532490674449303 0.764013716187645 0.764013716187645
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Ercc5 ENSMUSG00000026048 0.256244524152429 0.734217064895792 0.734217064895792 0.734217064895792 0.491912346974978 0.734217064895792
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Rfc1 ENSMUSG00000029191 0.800572997008854 0.899498104060749 0.532616737726862 0.899498104060749 0.899498104060749 0.899498104060749
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Pold3 ENSMUSG00000030726 0.993701561547226 0.993701561547226 0.755160586220134 0.993701561547226 0.607677218378262 0.993701561547226
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909

Renal cell carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tfe3 ENSMUSG00000000134 0.537823936328727 0.710577077617948 0.373886038349062 0.710577077617948 0.710577077617948 0.710577077617948
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Prcc ENSMUSG00000004895 0.635599661383936 0.635599661383936 0.0910004551454026 0.273001365436208 0.591238961662756 0.635599661383936
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Arnt ENSMUSG00000015522 0.737068311927084 0.911987634815449 0.834214517176173 0.911987634815449 0.911987634815449 0.911987634815449
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Fh1 ENSMUSG00000026526 0.413421954187514 0.577659121108702 0.227454698370132 0.577659121108702 0.577659121108702 0.577659121108702
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Slc2a1 ENSMUSG00000028645 0.558933957546336 0.558933957546336 0.422520935465457 0.558933957546336 0.532652567018012 0.558933957546336
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Flcn ENSMUSG00000032633 0.276517143972942 0.414775715959413 0.0997574634578557 0.299272390373567 0.834211485220143 0.834211485220143
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Egln3 ENSMUSG00000035105 0.871300299165209 0.871300299165209 0.553529755937991 0.871300299165209 0.760923769638067 0.871300299165209
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Egln2 ENSMUSG00000058709 0.419585870973821 0.629378806460731 0.302033889838096 0.629378806460731 0.940131257795237 0.940131257795237
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

Thyroid hormone signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Med16 ENSMUSG00000013833 0.194136441614885 0.436580885917762 0.291053923945175 0.436580885917762 0.701790446357526 0.701790446357526
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Med13l ENSMUSG00000018076 0.569606413049618 0.996851178979051 0.791434436575564 0.996851178979051 0.996851178979051 0.996851178979051
Med1 ENSMUSG00000018160 0.176912994511997 0.530738983535992 0.937088643933494 0.937088643933494 0.690096905754397 0.937088643933494
Ncor1 ENSMUSG00000018501 0.121956960752573 0.365870882257719 0.427124658562437 0.640686987843655 0.737052169627893 0.737052169627893
Hdac2 ENSMUSG00000019777 0.764097451408013 0.993700732114544 0.862102361923653 0.993700732114544 0.993700732114544 0.993700732114544
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Plcd3 ENSMUSG00000020937 0.19690131712475 0.59070395137425 0.424821026116843 0.637231539175265 0.803629830827979 0.803629830827979
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Med4 ENSMUSG00000022109 0.594007900130456 0.891011850195685 0.208123102342938 0.624369307028813 0.965367834542043 0.965367834542043
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Hdac3 ENSMUSG00000024454 0.406666578905776 0.797529485168917 0.56426299772485 0.797529485168917 0.797529485168917 0.797529485168917
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Plce1 ENSMUSG00000024998 0.825043160749253 0.962222498862426 0.962222498862426 0.962222498862426 0.852794201063591 0.962222498862426
Pfkfb2 ENSMUSG00000026409 0.550865257993181 0.725288879001407 0.716421397791646 0.725288879001407 0.725288879001407 0.725288879001407
Atp1b1 ENSMUSG00000026576 0.634531011731275 0.908652658781921 0.815579691658005 0.908652658781921 0.908652658781921 0.908652658781921
Med27 ENSMUSG00000026799 0.188742580635213 0.283113870952819 0.130086868464712 0.283113870952819 0.380314155487782 0.380314155487782
Notch1 ENSMUSG00000026923 0.322985784663396 0.669767231045251 0.669767231045251 0.669767231045251 0.489406609204599 0.669767231045251
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Ncoa3 ENSMUSG00000027678 0.227488300555456 0.593342114988912 0.746192865902166 0.746192865902166 0.395561409992608 0.593342114988912
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Slc2a1 ENSMUSG00000028645 0.558933957546336 0.558933957546336 0.422520935465457 0.558933957546336 0.532652567018012 0.558933957546336
Slc9a1 ENSMUSG00000028854 0.812652888266082 0.828011941681275 0.577549601155198 0.828011941681275 0.828011941681275 0.828011941681275
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Med17 ENSMUSG00000031935 0.773233922582795 0.773233922582795 0.75215585817309 0.773233922582795 0.66981399974883 0.773233922582795
Atp1b3 ENSMUSG00000032412 0.859029743648347 0.859029743648347 0.334753136803695 0.842391236549836 0.56159415769989 0.842391236549836
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Med30 ENSMUSG00000038622 0.974812698215822 0.974812698215822 0.527451989710235 0.974812698215822 0.949651629146872 0.974812698215822
Rxrb ENSMUSG00000039656 0.155039132458621 0.232558698687931 0.0843535974343253 0.232558698687931 0.550982840393409 0.550982840393409
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Med14 ENSMUSG00000064127 0.159665944223733 0.4789978326712 0.896381429694953 0.896381429694953 0.740156213379708 0.896381429694953
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Phosphatidylinositol signaling system

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Dgkq ENSMUSG00000004815 0.484189721597189 0.65824313249566 0.5882990648471 0.65824313249566 0.65824313249566 0.65824313249566
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr1 ENSMUSG00000015214 0.28209068750968 0.613378299339732 0.408918866226488 0.613378299339732 0.990553880737655 0.990553880737655
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Plcd3 ENSMUSG00000020937 0.19690131712475 0.59070395137425 0.424821026116843 0.637231539175265 0.803629830827979 0.803629830827979
Ippk ENSMUSG00000021385 0.496886488781754 0.943358849667233 0.943358849667233 0.943358849667233 0.68139363815062 0.943358849667233
Mtmr6 ENSMUSG00000021987 0.113641206247705 0.340923618743115 0.384520718380111 0.576781077570167 0.987405339532972 0.987405339532972
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Plce1 ENSMUSG00000024998 0.825043160749253 0.962222498862426 0.962222498862426 0.962222498862426 0.852794201063591 0.962222498862426
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Inpp1 ENSMUSG00000026102 0.806672191997436 0.806672191997436 0.501896590044763 0.764179279372299 0.509452852914866 0.764179279372299
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Inpp5b ENSMUSG00000028894 0.831196617340709 0.831196617340709 0.722292545166494 0.831196617340709 0.646912568962143 0.831196617340709
Cds1 ENSMUSG00000029330 0.825077241324923 0.852832655754643 0.852832655754643 0.852832655754643 0.831219326851047 0.852832655754643
Cdipt ENSMUSG00000030682 0.632599618115493 0.632599618115493 0.0957536977912475 0.287261093373743 0.393067572338565 0.589601358507848
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Ip6k1 ENSMUSG00000032594 0.413404704670262 0.413404704670262 0.324942120713975 0.413404704670262 0.357074936935405 0.413404704670262
Ip6k2 ENSMUSG00000032599 0.330788467532396 0.810695751302728 0.818916316535035 0.818916316535035 0.540463834201819 0.810695751302728
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Mtmr3 ENSMUSG00000034354 0.380119349028901 0.570179023543351 0.256261486022692 0.570179023543351 0.672559498007883 0.672559498007883
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Itpkb ENSMUSG00000038855 0.646948389636692 0.646948389636692 0.20385417619165 0.611562528574949 0.604962380872254 0.646948389636692
Pi4kb ENSMUSG00000038861 0.785002570027176 0.809512890262261 0.519502292050506 0.809512890262261 0.809512890262261 0.809512890262261
Dgkz ENSMUSG00000040479 0.434069574905165 0.646985853628045 0.646985853628045 0.646985853628045 0.519743903386424 0.646985853628045
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Itpk1 ENSMUSG00000057963 0.83737377730881 0.83737377730881 0.719396864399788 0.83737377730881 0.728283678868544 0.83737377730881
Dgkd ENSMUSG00000070738 0.464917814653946 0.697376721980919 0.417966730338601 0.697376721980919 0.868348927285061 0.868348927285061

Aminoacyl-tRNA biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hars ENSMUSG00000001380 0.479478713840439 0.834267200601315 0.902621329900911 0.902621329900911 0.55617813373421 0.834267200601315
Farsa ENSMUSG00000003808 0.540431778186929 0.641238432682586 0.138401252443015 0.415203757329045 0.641238432682586 0.641238432682586
Cars ENSMUSG00000010755 0.399626559901532 0.599439839852298 0.246402207737394 0.599439839852298 0.604726057558737 0.604726057558737
Nars2 ENSMUSG00000018995 0.141620097591508 0.192710133258816 0.0822225443117312 0.192710133258816 0.192710133258816 0.192710133258816
Hars2 ENSMUSG00000019143 0.230377459707673 0.499088525332771 0.332725683555181 0.499088525332771 0.965363705537922 0.965363705537922
Wars ENSMUSG00000021266 0.408885830291743 0.512017650355508 0.0887780489564179 0.266334146869254 0.512017650355508 0.512017650355508
Fars2 ENSMUSG00000021420 0.208145169082477 0.585816810723667 0.585816810723667 0.585816810723667 0.55093728810512 0.585816810723667
Nars ENSMUSG00000024587 0.624385232273242 0.933934829908431 0.632807255982011 0.933934829908431 0.933934829908431 0.933934829908431
Farsb ENSMUSG00000026245 0.646882293112957 0.746137479100506 0.740169869660117 0.746137479100506 0.746137479100506 0.746137479100506
Dars2 ENSMUSG00000026709 0.455288990771525 0.482002813456164 0.132103500545569 0.396310501636708 0.482002813456164 0.482002813456164
Tars2 ENSMUSG00000028107 0.205117650221314 0.307676475331971 0.0171198350396683 0.051359505119005 0.504146442433517 0.504146442433517
Yars ENSMUSG00000028811 0.317011759210847 0.47551763881627 0.159721674100946 0.47551763881627 0.678351748416951 0.678351748416951
Gars ENSMUSG00000029777 0.457502172080739 0.686253258121108 0.0421945903936256 0.126583771180877 0.924504978376358 0.924504978376358
Aars ENSMUSG00000031960 0.675452118250372 0.675452118250372 0.0549971798052389 0.164991539415717 0.486799825585686 0.675452118250372
Iars ENSMUSG00000037851 0.606103775038241 0.606103775038241 0.236723905901076 0.606103775038241 0.492460364926361 0.606103775038241
Vars2 ENSMUSG00000038838 0.401848336476575 0.602772504714862 0.29288102312272 0.602772504714862 0.666795592127169 0.666795592127169
Mars ENSMUSG00000040354 0.154941715865935 0.232412573798903 0.0343042790877651 0.102912837263295 0.933943177323667 0.933943177323667
Pars2 ENSMUSG00000043572 0.276429310220225 0.414643965330337 0.55089386034227 0.55089386034227 0.216867061554978 0.414643965330337
Mars2 ENSMUSG00000046994 0.641320503275625 0.641320503275625 0.355033334663456 0.590044684341132 0.393363122894088 0.590044684341132
Mtfmt ENSMUSG00000059183 0.955914172110071 0.97796073318477 0.97796073318477 0.97796073318477 0.615972405797389 0.97796073318477
Sars ENSMUSG00000068739 0.257922630318537 0.77376789095561 0.812792042678365 0.99685071623758 0.99685071623758 0.99685071623758
Sars2 ENSMUSG00000070699 0.0355635940785373 0.106690782235612 0.0794247797402692 0.119137169610404 0.618566628007189 0.618566628007189

Fanconi anemia pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Fance ENSMUSG00000007570 0.095706501306675 0.287119503920025 0.393223216571204 0.589834824856806 0.855882327545643 0.855882327545643
Rad51c ENSMUSG00000007646 0.558862186064833 0.88698773329794 0.88698773329794 0.88698773329794 0.649708749511075 0.88698773329794
Rev3l ENSMUSG00000019841 0.698836320625326 0.698836320625326 0.344802224705691 0.698836320625326 0.62441091085238 0.698836320625326
Fancc ENSMUSG00000021461 0.10483914522132 0.314517435663961 0.4869456968576 0.566921429433929 0.566921429433929 0.566921429433929
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Top3b ENSMUSG00000022779 0.410963074529826 0.616444611794738 0.955912695292835 0.955912695292835 0.388945708410341 0.616444611794738
Telo2 ENSMUSG00000024170 0.30008590627972 0.900257718839159 0.716416485739769 0.943348767764004 0.943348767764004 0.943348767764004
Mus81 ENSMUSG00000024906 0.317161644537185 0.317161644537185 0.309558578812616 0.317161644537185 0.309567687476581 0.317161644537185
2310003H01Rik ENSMUSG00000025384 0.324918975433978 0.487378463150967 0.166897119453255 0.487378463150967 0.591192347167402 0.591192347167402
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Rev1 ENSMUSG00000026082 0.77323705101421 0.79446707642379 0.749164886040425 0.79446707642379 0.79446707642379 0.79446707642379
Fancg ENSMUSG00000028453 0.632842106829348 0.800580125546944 0.303934036067089 0.800580125546944 0.800580125546944 0.800580125546944
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Fan1 ENSMUSG00000033458 0.0895463814162714 0.268639144248814 0.535210742769633 0.535210742769633 0.417936826467238 0.535210742769633
Fancd2 ENSMUSG00000034023 0.971642734179405 0.971642734179405 0.933888899380019 0.971642734179405 0.818914011107705 0.971642734179405
Poli ENSMUSG00000038425 0.849748769488958 0.849748769488958 0.825063038700067 0.849748769488958 0.764181583198166 0.849748769488958
Slx4 ENSMUSG00000039738 0.472155600959342 0.865220680142318 0.728303881107593 0.865220680142318 0.865220680142318 0.865220680142318
Fancm ENSMUSG00000055884 0.952794070099461 0.952794070099461 0.707657842777675 0.952794070099461 0.632848414648752 0.952794070099461
Slx1b ENSMUSG00000059772 0.273102203263939 0.819306609791816 0.809671281226618 0.955923206999278 0.955923206999278 0.955923206999278
Eme2 ENSMUSG00000073436 0.484457700482441 0.794981788107556 0.84354063447501 0.84354063447501 0.52998785873837 0.794981788107556
Fancf ENSMUSG00000092118 0.214013296666816 0.478566931506538 0.319044621004358 0.478566931506538 0.629979851869174 0.629979851869174

Lysine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Plod3 ENSMUSG00000004846 0.380091909254714 0.517071588356143 0.0459419319183677 0.137825795755103 0.517071588356143 0.517071588356143
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Ezh1 ENSMUSG00000006920 0.731186517986504 0.794448762522376 0.794448762522376 0.794448762522376 0.307423490626736 0.794448762522376
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Setdb1 ENSMUSG00000015697 1 1 0.621580171848279 1 0.86213837038904 1
Nsd1 ENSMUSG00000021488 0.218397043180379 0.58669583715306 0.39113055810204 0.58669583715306 0.773211132858076 0.773211132858076
Echs1 ENSMUSG00000025465 0.209631769282776 0.628895307848328 0.852821606773896 0.852821606773896 0.472161002715643 0.708241504073464
Suv39h2 ENSMUSG00000026646 0.261185658413157 0.666935657659126 0.49941465317225 0.666935657659126 0.666935657659126 0.666935657659126
Ash1l ENSMUSG00000028053 0.378153132937169 0.722398003757208 0.594008023836612 0.722398003757208 0.722398003757208 0.722398003757208
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Acat1 ENSMUSG00000032047 0.815788093313268 1 0.701672431130662 1 1 1
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Kmt2c ENSMUSG00000038056 0.443393251001119 0.725354865824759 0.604985703514021 0.725354865824759 0.725354865824759 0.725354865824759
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Suv39h1 ENSMUSG00000039231 0.300114033243424 0.523179722078619 0.348786481385746 0.523179722078619 0.63563708959381 0.63563708959381
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Setd2 ENSMUSG00000044791 0.467313888562916 0.877651292404873 0.806647171702163 0.877651292404873 0.877651292404873 0.877651292404873
Suv420h1 ENSMUSG00000045098 0.352900406954565 0.616037846775787 0.591252934622595 0.616037846775787 0.616037846775787 0.616037846775787
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Whsc1l1 ENSMUSG00000054823 0.42248651259866 0.927659144367208 0.927659144367208 0.927659144367208 0.834289240651817 0.927659144367208
Smyd3 ENSMUSG00000055067 0.44579048970704 0.655523192190828 0.655523192190828 0.655523192190828 0.464914868467631 0.655523192190828
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Prdm2 ENSMUSG00000057637 0.238362128004891 0.715086384014673 0.949651707740253 0.949651707740253 0.902626912290256 0.949651707740253
Suv420h2 ENSMUSG00000059851 0.837383680330376 0.837383680330376 0.828142751254817 0.837383680330376 0.524887626690907 0.837383680330376
Dot1l ENSMUSG00000061589 0.504435806113353 0.713518810138284 0.713518810138284 0.713518810138284 0.494387660202947 0.713518810138284
Camkmt ENSMUSG00000071037 0.51204997609742 0.76807496414613 0.489425553543675 0.76807496414613 0.990552829191558 0.990552829191558

SNARE interactions in vesicular transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Stx7 ENSMUSG00000019998 0.26059162029198 0.569387014641609 0.379591343094406 0.569387014641609 0.833763417728142 0.833763417728142
Vamp2 ENSMUSG00000020894 0.713533370673868 0.871452400328244 0.871452400328244 0.871452400328244 0.58854331361707 0.871452400328244
Stx8 ENSMUSG00000020903 0.896374250870299 0.949614261257672 0.599265189903315 0.949614261257672 0.949614261257672 0.949614261257672
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Bnip1 ENSMUSG00000024191 0.0346582671987526 0.0709621643207598 0.0473081095471732 0.0709621643207598 0.489381298258457 0.489381298258457
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Stx18 ENSMUSG00000029125 0.309581512482546 0.737857261122885 0.927674707753686 0.927674707753686 0.49190484074859 0.737857261122885
Stx2 ENSMUSG00000029428 0.719355599579255 0.719355599579255 0.271560552234986 0.719355599579255 0.542990086211729 0.719355599579255
Vamp1 ENSMUSG00000030337 0.655514768001473 0.921397961207922 0.921397961207922 0.921397961207922 0.564236999628338 0.921397961207922
Stx4a ENSMUSG00000030805 0.583114701383756 0.583114701383756 0.545715758505275 0.583114701383756 0.535245520817248 0.583114701383756
Stx3 ENSMUSG00000041488 0.681393705426648 0.815865784357065 0.566937683964792 0.815865784357065 0.815865784357065 0.815865784357065

Viral carcinogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Snd1 ENSMUSG00000001424 0.0564814342491834 0.127488435567892 0.0849922903785948 0.127488435567892 0.924487585768437 0.924487585768437
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Dnaja3 ENSMUSG00000004069 0.547437119643417 0.547437119643417 0.000271132710841474 0.000813398132524421 0.47858600904299 0.547437119643417
Hdac9 ENSMUSG00000004698 0.996850831238741 0.996850831238741 0.596722723534559 0.996850831238741 0.99055376368219 0.996850831238741
Ranbp1 ENSMUSG00000005732 0.2168241631995 0.522253467917789 0.474516424967816 0.522253467917789 0.522253467917789 0.522253467917789
Gtf2h1 ENSMUSG00000006599 0.0864439700177123 0.259331910053137 0.354993782966202 0.532490674449303 0.764013716187645 0.764013716187645
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Atp6v0d1 ENSMUSG00000013160 0.309561343978414 0.46434201596762 0.104014014296183 0.312042042888548 0.840455578977424 0.840455578977424
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Actn1 ENSMUSG00000015143 0.420154103278963 0.630231154918445 0.274989252554542 0.630231154918445 0.927669996297921 0.927669996297921
Atf6b ENSMUSG00000015461 0.54304529692876 0.758145501694573 0.431735618088027 0.758145501694573 0.758145501694573 0.758145501694573
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Hdac2 ENSMUSG00000019777 0.764097451408013 0.993700732114544 0.862102361923653 0.993700732114544 0.993700732114544 0.993700732114544
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Snw1 ENSMUSG00000021039 0.641262366426133 0.93708521614656 0.93708521614656 0.93708521614656 0.937083162009856 0.93708521614656
Traf3 ENSMUSG00000021277 0.996851024285757 0.996851024285757 0.50951720821185 0.996851024285757 0.974813654004815 0.996851024285757
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Scrib ENSMUSG00000022568 0.350743109367829 0.734006932422278 0.489337954948186 0.734006932422278 0.837331153976299 0.837331153976299
Usp7 ENSMUSG00000022710 0.514512015356096 0.924508754862752 0.905745698323521 0.924508754862752 0.924508754862752 0.924508754862752
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Hdac3 ENSMUSG00000024454 0.406666578905776 0.797529485168917 0.56426299772485 0.797529485168917 0.797529485168917 0.797529485168917
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Ube3a ENSMUSG00000025326 0.0100021217833753 0.030006365350126 0.0964484346882663 0.144672652032399 0.522158709680698 0.522158709680698
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Creb3 ENSMUSG00000028466 0.324487693653349 0.714889048082817 0.476592698721878 0.714889048082817 0.924511841235858 0.924511841235858
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Rasa2 ENSMUSG00000032413 0.646610455952296 0.713461892649843 0.713461892649843 0.713461892649843 0.550421360042388 0.713461892649843
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Egr3 ENSMUSG00000033730 0.681142466358106 0.681142466358106 0.599267460683468 0.681142466358106 0.68009771036344 0.681142466358106
Egr2 ENSMUSG00000037868 0.48859656608548 0.573870218118701 0.552913061760835 0.573870218118701 0.573870218118701 0.573870218118701
Rbpj ENSMUSG00000039191 0.855923261172793 0.855923261172793 0.54306369608504 0.846381237030571 0.564254158020381 0.846381237030571
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Atf4 ENSMUSG00000042406 0.971660975411842 0.971660975411842 0.3738723428701 0.971660975411842 0.81891333536232 0.971660975411842
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Ubr4 ENSMUSG00000066036 0.911955765287219 0.911955765287219 0.752169941463026 0.911955765287219 0.73707734465406 0.911955765287219
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Tbpl1 ENSMUSG00000071359 0.275013205568797 0.412519808353195 0.946502446975898 0.946502446975898 0.24312159998559 0.412519808353195
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Salmonella infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dynlt1c ENSMUSG00000000579 0.883899760990688 0.883899760990688 0.80057613627577 0.883899760990688 0.369654509250151 0.883899760990688
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Cse1l ENSMUSG00000002718 0.137331609166708 0.205997413750061 0.119278687130826 0.205997413750061 0.782320660147562 0.782320660147562
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Txn2 ENSMUSG00000005354 0.0964782040204012 0.144717306030602 0.0434143896562025 0.130243168968607 0.243191665062254 0.243191665062254
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Rala ENSMUSG00000008859 0.132136187857033 0.3964085635711 0.812792227354046 0.815861260968715 0.815861260968715 0.815861260968715
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Rock2 ENSMUSG00000020580 0.205255555469948 0.615766666409843 0.695940548463652 0.955931174349073 0.955931174349073 0.955931174349073
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Exoc2 ENSMUSG00000021357 0.874544623073993 0.921406376481653 0.921406376481653 0.921406376481653 0.707632544124845 0.921406376481653
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Flnb ENSMUSG00000025278 0.818798507891002 0.993698882827161 0.993698882827161 0.993698882827161 0.669628057582967 0.993698882827161
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Arl8a ENSMUSG00000026426 0.883895371529603 0.952796286260765 0.952796286260765 0.952796286260765 0.902621924968746 0.952796286260765
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Acbd3 ENSMUSG00000026499 0.395541099860182 0.82815469005804 0.82815469005804 0.82815469005804 0.812796597852325 0.82815469005804
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Vps39 ENSMUSG00000027291 0.44101937065803 0.661529055987045 0.959083038413344 0.959083038413344 0.373810060300631 0.661529055987045
Vps16 ENSMUSG00000027411 0.378138396297234 0.981105720713944 0.981105720713944 0.981105720713944 0.73723542237056 0.981105720713944
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Plekhm2 ENSMUSG00000028917 0.927533310597802 0.937014186226806 0.937014186226806 0.937014186226806 0.890034198563388 0.937014186226806
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps11 ENSMUSG00000032127 0.663871907655186 0.663871907655186 0.63003600227721 0.663871907655186 0.256028249598549 0.663871907655186
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Snx33 ENSMUSG00000032733 0.189891406937959 0.291033536953474 0.194022357968983 0.291033536953474 0.566752144116928 0.566752144116928
Myo6 ENSMUSG00000033577 0.868347441643257 0.868347441643257 0.764180433066279 0.868347441643257 0.687185524914462 0.868347441643257
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Vps18 ENSMUSG00000034216 0.292750989010855 0.439126483516282 0.243185531744507 0.439126483516282 0.97166562509085 0.97166562509085
Myl12b ENSMUSG00000034868 0.479455362371212 0.82648107226288 0.88699382740213 0.88699382740213 0.550987381508587 0.82648107226288
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Tab3 ENSMUSG00000035476 0.334634039301788 0.843502394766919 0.843502394766919 0.843502394766919 0.574862799578782 0.843502394766919
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Gcc2 ENSMUSG00000038039 0.716475625656991 0.981108941481227 0.822001616067604 0.981108941481227 0.981108941481227 0.981108941481227
Rilp ENSMUSG00000038195 0.375511324240749 0.563266986361123 0.0672118419166119 0.201635525749836 0.782041814431392 0.782041814431392
Il18 ENSMUSG00000039217 0.496837963408829 0.984253479233263 0.91827227087713 0.984253479233263 0.984253479233263 0.984253479233263
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Snx18 ENSMUSG00000042364 0.943364570458388 0.943364570458388 0.773208249776485 0.943364570458388 0.831192568403244 0.943364570458388
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Exoc5 ENSMUSG00000061244 0.108322260304065 0.324966780912195 0.355026060691986 0.532539091037979 0.921401924246316 0.921401924246316
Arf2 ENSMUSG00000062421 0.933948983315106 0.94022758133894 0.94022758133894 0.94022758133894 0.746185886368294 0.94022758133894
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106

Insulin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Sh2b2 ENSMUSG00000005057 0.915109846377157 0.99685090403113 0.99685090403113 0.99685090403113 0.974803646562118 0.99685090403113
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Srebf1 ENSMUSG00000020538 0.0378624988392813 0.113587496517844 0.743151276644179 0.924508258653007 0.924508258653007 0.924508258653007
Fbp2 ENSMUSG00000021456 0.936625756886819 0.936625756886819 0.46141901392199 0.904917352190218 0.603278234793479 0.904917352190218
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Fasn ENSMUSG00000025153 0.553573885904949 0.915138858798145 0.915138858798145 0.915138858798145 0.710492256509747 0.915138858798145
Rptor ENSMUSG00000025583 0.664108758918949 0.701783944724874 0.340784524476415 0.701783944724874 0.701783944724874 0.701783944724874
Ptpn1 ENSMUSG00000027540 0.574931513764371 0.915126943884423 0.770209866679489 0.915126943884423 0.915126943884423 0.915126943884423
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Rps6 ENSMUSG00000028495 0.332453418387945 0.367177841714712 0.0428179702760643 0.128453910828193 0.367177841714712 0.367177841714712
Mknk1 ENSMUSG00000028708 0.776273355728455 0.776273355728455 0.743196779543328 0.776273355728455 0.445796596672212 0.776273355728455
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Phkg2 ENSMUSG00000030815 0.858989506418691 0.858989506418691 0.692873593181419 0.858989506418691 0.834303082782259 0.858989506418691
Phka2 ENSMUSG00000031295 0.357024957981122 0.657998240185373 0.776263457440659 0.776263457440659 0.438665493456916 0.657998240185373
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Ptprf ENSMUSG00000033295 0.519575906867502 0.877666014009073 0.877666014009073 0.877666014009073 0.803587652118962 0.877666014009073
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
G6pc3 ENSMUSG00000034793 0.175411584724297 0.263117377086445 0.124108250719009 0.263117377086445 0.96534228681455 0.96534228681455
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Prkci ENSMUSG00000037643 0.553540357187378 0.99055225528109 0.99055225528109 0.99055225528109 0.815837729934611 0.99055225528109
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Ppp1ca ENSMUSG00000040385 0.146984170341655 0.220476255512483 0.0121365677036429 0.0364097031109288 0.550760247056706 0.550760247056706
Pck2 ENSMUSG00000040618 0.257893691186856 0.386840536780284 0.201052471017059 0.386840536780284 0.812767660690678 0.812767660690678
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Gck ENSMUSG00000041798 0.740082185769287 0.763998372565369 0.731177852381581 0.763998372565369 0.763998372565369 0.763998372565369
Acacb ENSMUSG00000042010 0.601592849200848 0.710101477393061 0.233677746371738 0.701033239115215 0.710101477393061 0.710101477393061
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Ppp1r3e ENSMUSG00000072494 0.887016765495874 0.984256638411033 0.630038105509531 0.984256638411033 0.984256638411033 0.984256638411033

Neurotrophin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ngfr ENSMUSG00000000120 0.268199517937272 0.804598553811816 0.632654015298236 0.948981022947353 1 1
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Sh2b2 ENSMUSG00000005057 0.915109846377157 0.99685090403113 0.99685090403113 0.99685090403113 0.974803646562118 0.99685090403113
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Map3k3 ENSMUSG00000020700 0.661219915180198 0.722386292064305 0.722386292064305 0.722386292064305 0.687156393087246 0.722386292064305
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Zfp369 ENSMUSG00000021514 0.20964972716018 0.628949181480541 0.701742419402315 0.927659031552377 0.927659031552377 0.927659031552377
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Arhgdia ENSMUSG00000025132 0.422341226463687 0.63351183969553 0.300219684414466 0.63351183969553 0.752082591720677 0.752082591720677
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Sh2b1 ENSMUSG00000030733 0.834241687765825 0.834241687765825 0.509532263445638 0.834241687765825 0.794394779868564 0.834241687765825
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Prdm4 ENSMUSG00000035529 0.852579873896299 0.92767006878883 0.92767006878883 0.92767006878883 0.902447406604719 0.92767006878883
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Atf4 ENSMUSG00000042406 0.971660975411842 0.971660975411842 0.3738723428701 0.971660975411842 0.81891333536232 0.971660975411842
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Ntf3 ENSMUSG00000049107 0.785026324408054 0.785026324408054 0.213873324120611 0.510449201721027 0.340299467814018 0.510449201721027
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Map2k5 ENSMUSG00000058444 0.722355073464935 0.905737421087041 0.359132765190101 0.905737421087041 0.905737421087041 0.905737421087041
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Map3k5 ENSMUSG00000071369 0.946505334041831 0.946505334041831 0.464790285810797 0.946505334041831 0.883889101846502 0.946505334041831

Fc gamma R-mediated phagocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Gab2 ENSMUSG00000004508 0.868287828848052 0.868287828848052 0.602160705619134 0.868287828848052 0.797435929075083 0.868287828848052
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Limk2 ENSMUSG00000020451 0.543002672756508 0.758163298721203 0.72236830548959 0.758163298721203 0.758163298721203 0.758163298721203
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Asap1 ENSMUSG00000022377 0.770211163763636 0.952793301476563 0.566942451615172 0.952793301476563 0.952793301476563 0.952793301476563
Bin1 ENSMUSG00000024381 0.574927196052138 0.577653294094102 0.373888017702025 0.577653294094102 0.577653294094102 0.577653294094102
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Marcksl1 ENSMUSG00000047945 0.758182321493367 0.993701906168428 0.915135366039107 0.993701906168428 0.993701906168428 0.993701906168428
Asap2 ENSMUSG00000052632 0.722326372802845 0.722326372802845 0.233676224726245 0.701028674178735 0.499328995561434 0.722326372802845
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Cfl1 ENSMUSG00000056201 0.905623098282885 0.905623098282885 0.593568983517392 0.905623098282885 0.828088088136392 0.905623098282885
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Marcks ENSMUSG00000069662 0.484471332898479 0.540446086496906 0.219941728657362 0.540446086496906 0.540446086496906 0.540446086496906
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612
PLA2G4B ENSMUSG00000098488 0.291048191351063 0.87314457405319 0.899503428156711 0.899503428156711 0.825074647057623 0.899503428156711

Bacterial invasion of epithelial cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Clta ENSMUSG00000028478 0.626800882680685 0.626800882680685 0.154929734580531 0.464789203741594 0.51934836378858 0.626800882680685
Mad2l2 ENSMUSG00000029003 0.0163341725967249 0.0490025177901746 0.211013925138425 0.316520887707637 0.794360760642728 0.794360760642728
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Ilk ENSMUSG00000030890 0.239910877958419 0.359866316937629 0.0948797442637955 0.284639232791386 0.734262682112775 0.734262682112775
Cttn ENSMUSG00000031078 0.890132912119958 0.890132912119958 0.550893815794547 0.890132912119958 0.752121469870449 0.890132912119958
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Sept6 ENSMUSG00000050379 0.71352514240849 0.855938727580137 0.767209191602458 0.855938727580137 0.855938727580137 0.855938727580137
Sept11 ENSMUSG00000058013 0.933945193773051 0.933945193773051 0.902611341952721 0.933945193773051 0.843521707942754 0.933945193773051
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002
Sept9 ENSMUSG00000059248 0.330783049710831 0.517130382197397 0.344753588131598 0.517130382197397 0.695937353587286 0.695937353587286
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

Chronic myeloid leukemia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Gab2 ENSMUSG00000004508 0.868287828848052 0.868287828848052 0.602160705619134 0.868287828848052 0.797435929075083 0.868287828848052
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Bcl2l1 ENSMUSG00000007659 0.746191168970411 0.874557446877584 0.153856089929605 0.461568269788813 0.874557446877584 0.874557446877584
Bcr ENSMUSG00000009681 0.974807332533465 0.974807332533465 0.707597015236092 0.974807332533465 0.785355793137647 0.974807332533465
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Hdac2 ENSMUSG00000019777 0.764097451408013 0.993700732114544 0.862102361923653 0.993700732114544 0.993700732114544 0.993700732114544
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Ctbp2 ENSMUSG00000030970 0.883902463930184 0.918273634779434 0.852839917479334 0.918273634779434 0.918273634779434 0.918273634779434
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Ribosome biogenesis in eukaryotes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nob1 ENSMUSG00000003848 0.773248898466916 0.821999622588008 0.821999622588008 0.821999622588008 0.561600850274487 0.821999622588008
Nxf2 ENSMUSG00000009941 0.786978026679402 0.786978026679402 0.372444347651897 0.786978026679402 0.627597529784779 0.786978026679402
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Rrp7a ENSMUSG00000018040 0.692852013372061 0.883803684161346 0.681326374472611 0.883803684161346 0.883803684161346 0.883803684161346
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Gtpbp4 ENSMUSG00000021149 0.206767771593221 0.428184775281892 0.285456516854594 0.428184775281892 0.825001133305697 0.825001133305697
Riok1 ENSMUSG00000021428 0.479497884306649 0.719246826459974 0.317055166607037 0.719246826459974 0.943354933777801 0.943354933777801
Pop1 ENSMUSG00000022325 0.550930964020102 0.894951498773524 0.993701690259314 0.993701690259314 0.596634332515683 0.894951498773524
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Sbds ENSMUSG00000025337 0.440975599729525 0.661463399594287 0.292724844309227 0.661463399594287 0.855928799100936 0.855928799100936
Wdr75 ENSMUSG00000025995 0.328827310390672 0.493240965586008 0.283816811800618 0.493240965586008 0.865239864601655 0.865239864601655
Nvl ENSMUSG00000026516 0.371681881011985 0.752130336136522 0.610460389944725 0.752130336136522 0.752130336136522 0.752130336136522
Nat10 ENSMUSG00000027185 0.812804065976706 0.837394100725064 0.67561800965928 0.837394100725064 0.837394100725064 0.837394100725064
Nop56 ENSMUSG00000027405 0.51207682286063 0.616015484623619 0.613172662491066 0.616015484623619 0.616015484623619 0.616015484623619
Spata5 ENSMUSG00000027722 0.698826879621654 0.933948335827908 0.89636896934003 0.933948335827908 0.933948335827908 0.933948335827908
Gar1 ENSMUSG00000028010 0.143706972836139 0.431120918508418 0.361201474840207 0.541802212260311 0.871407813680735 0.871407813680735
Gnl2 ENSMUSG00000028869 0.693020293608372 0.693020293608372 0.138405868010039 0.415217604030117 0.585802442112524 0.693020293608372
Rbm28 ENSMUSG00000029701 0.228992467475281 0.686977402425843 0.815858413486353 0.815858413486353 0.599488354452052 0.815858413486353
Pop7 ENSMUSG00000029715 0.033955668492766 0.050933502739149 0.00447235388694376 0.0134170616608313 0.243186589222412 0.243186589222412
Bms1 ENSMUSG00000030138 0.852810376510079 0.852810376510079 0.585806547581933 0.852810376510079 0.713480715892769 0.852810376510079
Pop4 ENSMUSG00000030423 0.262959296901949 0.719444773635942 0.687184134716508 0.719444773635942 0.719444773635942 0.719444773635942
Dkc1 ENSMUSG00000031403 0.532640609557704 0.798960914336556 0.49441725517968 0.798960914336556 0.837387171922872 0.837387171922872
Xrn1 ENSMUSG00000032410 0.160890735972028 0.352894754717987 0.235263169811991 0.352894754717987 0.627232733306543 0.627232733306543
Pwp2 ENSMUSG00000032834 0.199669971734496 0.299504957601743 0.0696231421464657 0.208869426439397 0.646960891212126 0.646960891212126
Wdr3 ENSMUSG00000033285 0.522205583831546 0.783308375747319 0.899486392537053 0.899486392537053 0.315242060316648 0.783308375747319
Utp6 ENSMUSG00000035575 0.0430055834547232 0.12901675036417 0.144882604793049 0.217323907189574 0.7641958689898 0.7641958689898
Tbl3 ENSMUSG00000040688 0.0916980582103184 0.137547087315478 0.00975864054692178 0.0292759216407653 0.149260377687781 0.149260377687781
Cirh1a ENSMUSG00000041438 0.338768556428345 0.764282629999178 0.946507266444644 0.946507266444644 0.509521753332785 0.764282629999178
Utp15 ENSMUSG00000041747 0.722343772711313 0.722343772711313 0.569577633307332 0.722343772711313 0.616004479594876 0.722343772711313
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Rexo1 ENSMUSG00000047417 0.669685868039949 0.669685868039949 0.391172185831307 0.669685868039949 0.51698966825319 0.669685868039949
Rpp38 ENSMUSG00000049950 0.687207765564406 0.687207765564406 0.596691132650808 0.687207765564406 0.669784975628704 0.687207765564406
Heatr1 ENSMUSG00000050244 0.746181096159091 0.752175054763424 0.752175054763424 0.752175054763424 0.698862686730887 0.752175054763424
Utp18 ENSMUSG00000054079 0.825030315297898 0.825030315297898 0.219866547684685 0.659599643054055 0.773197603599864 0.825030315297898
Mdn1 ENSMUSG00000058006 0.678455832733269 0.821958350336563 0.797484748462971 0.821958350336563 0.821958350336563 0.821958350336563
Pop5 ENSMUSG00000060152 0.0671949029979054 0.201584708993716 0.216937100688497 0.325405651032745 0.797510992281636 0.797510992281636
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Utp14b ENSMUSG00000079470 0.0933093793818094 0.279928138145428 0.984256875668141 0.984256875668141 0.408888137738768 0.613332206608151
Rasl2-9 ENSMUSG00000083649 0.24756818392405 0.513203260175477 0.342135506783651 0.513203260175477 0.849660421146472 0.849660421146472

Endometrial cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Ilk ENSMUSG00000030890 0.239910877958419 0.359866316937629 0.0948797442637955 0.284639232791386 0.734262682112775 0.734262682112775
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Autophagy - other

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Atg2a ENSMUSG00000024773 0.463648979381158 1 0.874427498800855 1 1 1
Rptor ENSMUSG00000025583 0.664108758918949 0.701783944724874 0.340784524476415 0.701783944724874 0.701783944724874 0.701783944724874
Atg4b ENSMUSG00000026280 0.940212228542754 0.940212228542754 0.0902738449647753 0.270821534894326 0.298282947773483 0.447424421660224
Atg16l1 ENSMUSG00000026289 0.918269688368391 0.918269688368391 0.828149419912083 0.918269688368391 0.725337615491778 0.918269688368391
Atg4c ENSMUSG00000028550 0.965373318266653 0.965373318266653 0.646988206219499 0.965373318266653 0.952795444050959 0.965373318266653
Wipi2 ENSMUSG00000029578 0.504266733604144 0.504266733604144 0.165737192219274 0.497211576657822 0.431517931610113 0.504266733604144
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Atg12 ENSMUSG00000032905 0.399989119756591 0.943367739510359 0.743193874058818 0.943367739510359 0.943367739510359 0.943367739510359
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
9430023L20Rik ENSMUSG00000037204 0.0584555665933076 0.175366699779923 0.927677413404358 0.927677413404358 0.767005890614081 0.927677413404358
Atg2b ENSMUSG00000041341 0.90883639295229 0.965358294616816 0.607736332962354 0.965358294616816 0.965358294616816 0.965358294616816

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pigl ENSMUSG00000014245 0.713504308576772 0.977959476008201 0.977959476008201 0.977959476008201 0.602166388613618 0.977959476008201
Pigt ENSMUSG00000017721 0.698534474020628 0.752174519354127 0.752174519354127 0.752174519354127 0.618477155240358 0.752174519354127
Pigh ENSMUSG00000021120 0.486923236887201 0.840470186112147 0.831219976620384 0.840470186112147 0.840470186112147 0.840470186112147
Gpaa1 ENSMUSG00000022561 0.140166511072528 0.210249766608792 0.0554643222446901 0.16639296673407 0.41514481101606 0.41514481101606
Pigq ENSMUSG00000025728 0.927450586533143 0.927450586533143 0.264110142204604 0.611288452668792 0.407525635112528 0.611288452668792
Dpm2 ENSMUSG00000026810 0.324494861834532 0.50685771288579 0.50685771288579 0.50685771288579 0.365213878733351 0.50685771288579
Pigo ENSMUSG00000028454 0.0194435498901835 0.0583306496705506 0.23672548471096 0.288558854751092 0.288558854751092 0.288558854751092
Pigu ENSMUSG00000038383 0.176926134305675 0.530778402917025 0.883880384398204 0.883880384398204 0.610420955622581 0.883880384398204
Pigk ENSMUSG00000039047 0.758182007536299 0.758182007536299 0.62163877745223 0.758182007536299 0.719426675472166 0.758182007536299
Pigs ENSMUSG00000041958 0.420220167764266 0.630330251646399 0.141622561647642 0.424867684942927 0.984256431021961 0.984256431021961
Pign ENSMUSG00000056536 0.644152170417337 0.89013588636369 0.3889673718324 0.89013588636369 0.89013588636369 0.89013588636369
Pgap1 ENSMUSG00000073678 0.434024879763406 0.818907750235861 0.553616938893275 0.818907750235861 0.818907750235861 0.818907750235861
Pigb ENSMUSG00000079469 0.937071267899132 0.937071267899132 0.424778166119504 0.654357997262867 0.436238664841912 0.654357997262867

AMPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Srebf1 ENSMUSG00000020538 0.0378624988392813 0.113587496517844 0.743151276644179 0.924508258653007 0.924508258653007 0.924508258653007
Ppp2r3c ENSMUSG00000021022 0.545632448057358 0.818448672086036 0.29469936421847 0.818448672086036 0.93393928372919 0.93393928372919
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Fbp2 ENSMUSG00000021456 0.936625756886819 0.936625756886819 0.46141901392199 0.904917352190218 0.603278234793479 0.904917352190218
Hmgcr ENSMUSG00000021670 0.408770319401007 0.974804929801356 0.974804929801356 0.974804929801356 0.834305763268272 0.974804929801356
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Fasn ENSMUSG00000025153 0.553573885904949 0.915138858798145 0.915138858798145 0.915138858798145 0.710492256509747 0.915138858798145
Pfkfb1 ENSMUSG00000025271 0.588492130656257 0.882738195984386 0.38406707812773 0.882738195984386 0.905667774593432 0.905667774593432
Rptor ENSMUSG00000025583 0.664108758918949 0.701783944724874 0.340784524476415 0.701783944724874 0.701783944724874 0.701783944724874
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Pfkfb2 ENSMUSG00000026409 0.550865257993181 0.725288879001407 0.716421397791646 0.725288879001407 0.725288879001407 0.725288879001407
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Creb3 ENSMUSG00000028466 0.324487693653349 0.714889048082817 0.476592698721878 0.714889048082817 0.924511841235858 0.924511841235858
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Tbc1d1 ENSMUSG00000029174 0.695891420155379 0.981104615106965 0.981104615106965 0.981104615106965 0.837354825798216 0.981104615106965
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
G6pc3 ENSMUSG00000034793 0.175411584724297 0.263117377086445 0.124108250719009 0.263117377086445 0.96534228681455 0.96534228681455
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Pck2 ENSMUSG00000040618 0.257893691186856 0.386840536780284 0.201052471017059 0.386840536780284 0.812767660690678 0.812767660690678
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Acacb ENSMUSG00000042010 0.601592849200848 0.710101477393061 0.233677746371738 0.701033239115215 0.710101477393061 0.710101477393061
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Strada ENSMUSG00000069631 0.616044905623391 0.749180724093663 0.749180724093663 0.749180724093663 0.661234749505122 0.749180724093663
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Mlycd ENSMUSG00000074064 0.00963621921909754 0.0289086576572926 0.0246833949730073 0.0370250924595109 0.598681724301418 0.598681724301418
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138

Yersinia infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Tbk1 ENSMUSG00000020115 0.384609190534306 0.915614726483065 0.955930879339086 0.955930879339086 0.610409817655377 0.915614726483065
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Rock2 ENSMUSG00000020580 0.205255555469948 0.615766666409843 0.695940548463652 0.955931174349073 0.955931174349073 0.955931174349073
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Gnaq ENSMUSG00000024639 0.822005798248339 0.822005798248339 0.658382968346436 0.822005798248339 0.661235388260116 0.822005798248339
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Nfatc2 ENSMUSG00000027544 0.905743330627905 0.930803033454725 0.655513435915049 0.930803033454725 0.930803033454725 0.930803033454725
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Ccl2 ENSMUSG00000035385 0.598218036397384 0.830987046359667 0.401124167843243 0.830987046359667 0.830987046359667 0.830987046359667
Wipf2 ENSMUSG00000038013 0.438729632472415 0.984256898514555 0.852842402789194 0.984256898514555 0.984256898514555 0.984256898514555
Il18 ENSMUSG00000039217 0.496837963408829 0.984253479233263 0.91827227087713 0.984253479233263 0.984253479233263 0.984253479233263
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Git2 ENSMUSG00000041890 0.764159983468941 0.764159983468941 0.607690584697949 0.764159983468941 0.213966028814276 0.641898086442827
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002
Ptk2b ENSMUSG00000059456 0.865237524745001 0.927658298243105 0.927658298243105 0.927658298243105 0.806650982526346 0.927658298243105
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

Notch signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Ncstn ENSMUSG00000003458 0.686908775780357 0.831051100070182 0.713308751115823 0.831051100070182 0.831051100070182 0.831051100070182
Hdac2 ENSMUSG00000019777 0.764097451408013 0.993700732114544 0.862102361923653 0.993700732114544 0.993700732114544 0.993700732114544
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Snw1 ENSMUSG00000021039 0.641262366426133 0.93708521614656 0.93708521614656 0.93708521614656 0.937083162009856 0.93708521614656
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Tle4 ENSMUSG00000024642 0.602224179001979 0.890139481950588 0.494410448307339 0.890139481950588 0.890139481950588 0.890139481950588
Rfng ENSMUSG00000025158 0.658330630439576 0.877658152303399 0.365424862940985 0.877658152303399 0.877658152303399 0.877658152303399
Notch1 ENSMUSG00000026923 0.322985784663396 0.669767231045251 0.669767231045251 0.669767231045251 0.489406609204599 0.669767231045251
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Lfng ENSMUSG00000029570 0.752147664128342 0.890134838092234 0.877663398126988 0.890134838092234 0.890134838092234 0.890134838092234
Dtx1 ENSMUSG00000029603 0.90261122290122 0.984252508419467 0.86211762551799 0.984252508419467 0.984252508419467 0.984252508419467
Ctbp2 ENSMUSG00000030970 0.883902463930184 0.918273634779434 0.852839917479334 0.918273634779434 0.918273634779434 0.918273634779434
Maml2 ENSMUSG00000031925 0.877637040192188 0.877637040192188 0.843497733680374 0.877637040192188 0.344585874854108 0.877637040192188
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Rbpj ENSMUSG00000039191 0.855923261172793 0.855923261172793 0.54306369608504 0.846381237030571 0.564254158020381 0.846381237030571
Dtx4 ENSMUSG00000039982 0.840453891252063 0.840453891252063 0.422422842991385 0.798946275743253 0.532630850495502 0.798946275743253
Cir1 ENSMUSG00000041777 0.320838616550758 0.481257924826137 0.273173561544034 0.481257924826137 0.84972641922385 0.84972641922385
Atxn1 ENSMUSG00000046876 0.638476495740401 0.764198398761101 0.764198398761101 0.764198398761101 0.393346970392926 0.764198398761101
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Maml3 ENSMUSG00000061143 0.734134168310536 0.828152725615866 0.828152725615866 0.828152725615866 0.752082162914131 0.828152725615866
Atxn1l ENSMUSG00000069895 0.880783936374026 0.880783936374026 0.583086871773137 0.880783936374026 0.690055898336966 0.880783936374026

Choline metabolism in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Dgkq ENSMUSG00000004815 0.484189721597189 0.65824313249566 0.5882990648471 0.65824313249566 0.65824313249566 0.65824313249566
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Ralgds ENSMUSG00000026821 0.812804004429882 0.812804004429882 0.583105102689558 0.812804004429882 0.543088585547914 0.812804004429882
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Slc44a1 ENSMUSG00000028412 0.815866632455274 0.815866632455274 0.509493249568485 0.764239874352727 0.415643682473567 0.764239874352727
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Dgkz ENSMUSG00000040479 0.434069574905165 0.646985853628045 0.646985853628045 0.646985853628045 0.519743903386424 0.646985853628045
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Chpt1 ENSMUSG00000060002 0.865242889840744 0.927670415131274 0.448134380939566 0.927670415131274 0.927670415131274 0.927670415131274
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Dgkd ENSMUSG00000070738 0.464917814653946 0.697376721980919 0.417966730338601 0.697376721980919 0.868348927285061 0.868348927285061
PLA2G4B ENSMUSG00000098488 0.291048191351063 0.87314457405319 0.899503428156711 0.899503428156711 0.825074647057623 0.899503428156711

Glycerophospholipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pla1a ENSMUSG00000002847 0.858985904894286 0.943339660366733 0.943339660366733 0.943339660366733 0.678302097204806 0.943339660366733
Pnpla6 ENSMUSG00000004565 0.328721727659331 0.493082591488996 0.242715044767789 0.493082591488996 0.7134020315329 0.7134020315329
Dgkq ENSMUSG00000004815 0.484189721597189 0.65824313249566 0.5882990648471 0.65824313249566 0.65824313249566 0.65824313249566
Taz ENSMUSG00000009995 0.050568810778851 0.151706432336553 0.350844856540626 0.397745380880109 0.397745380880109 0.397745380880109
Pgs1 ENSMUSG00000017715 0.208198797200108 0.391954784599189 0.261303189732793 0.391954784599189 0.77626936738718 0.77626936738718
Lpin1 ENSMUSG00000020593 0.395325022957911 0.592987534436867 0.23350601335978 0.592987534436867 0.877614220860537 0.877614220860537
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Lpcat1 ENSMUSG00000021608 0.484463417432125 0.484463417432125 0.25128699156916 0.484463417432125 0.469752465544028 0.484463417432125
Pisd ENSMUSG00000023452 0.672538904583506 0.902609274723723 0.902609274723723 0.902609274723723 0.707491599085882 0.902609274723723
Agpat4 ENSMUSG00000023827 0.580376959010968 0.580376959010968 0.259547477740451 0.467077979851395 0.31138531990093 0.467077979851395
Ptdss2 ENSMUSG00000025495 0.574481726274386 0.574481726274386 0.0459589726116633 0.13787691783499 0.561089325177004 0.574481726274386
Lpgat1 ENSMUSG00000026623 0.52712305525966 0.927622887535284 0.868316085785512 0.927622887535284 0.927622887535284 0.927622887535284
Gpd2 ENSMUSG00000026827 0.770211837240975 0.940220286237586 0.607726703074384 0.940220286237586 0.940220286237586 0.940220286237586
Lpcat4 ENSMUSG00000027134 0.899501162449904 0.968519369497954 0.924540298755749 0.968519369497954 0.968519369497954 0.968519369497954
Crls1 ENSMUSG00000027357 0.203902734612843 0.611708203838528 0.834301386897397 0.834301386897397 0.635642791570333 0.834301386897397
Lypla2 ENSMUSG00000028670 0.663789596191518 0.943315052868068 0.205273622877916 0.615820868633747 0.943315052868068 0.943315052868068
Pla2g2c ENSMUSG00000028750 0.721808504453124 0.721808504453124 0.608768048653419 0.721808504453124 0.260002570748384 0.721808504453124
Cds1 ENSMUSG00000029330 0.825077241324923 0.852832655754643 0.852832655754643 0.852832655754643 0.831219326851047 0.852832655754643
Etnk1 ENSMUSG00000030275 0.95592624690547 0.95592624690547 0.375943844636861 0.95592624690547 0.758123197522832 0.95592624690547
Cdipt ENSMUSG00000030682 0.632599618115493 0.632599618115493 0.0957536977912475 0.287261093373743 0.393067572338565 0.589601358507848
Ppapdc1b ENSMUSG00000031570 0.818896876639292 0.893239279882947 0.893239279882947 0.893239279882947 0.572286243607558 0.893239279882947
Pla2g15 ENSMUSG00000031903 0.196747826323332 0.295121739484998 0.15254254211582 0.295121739484998 0.602228479811121 0.602228479811121
Lpcat2 ENSMUSG00000033192 0.690043714458379 0.690043714458379 0.566737170887083 0.690043714458379 0.30191632312261 0.690043714458379
Agpat1 ENSMUSG00000034254 0.797176717981107 0.930696761654645 0.655475410945114 0.930696761654645 0.930696761654645 0.930696761654645
Mboat7 ENSMUSG00000035596 0.918269279145594 0.943367638512925 0.743178985363091 0.943367638512925 0.943367638512925 0.943367638512925
Dgkz ENSMUSG00000040479 0.434069574905165 0.646985853628045 0.646985853628045 0.646985853628045 0.519743903386424 0.646985853628045
Cept1 ENSMUSG00000040774 0.013199221641137 0.0395976649234111 0.0336032486880714 0.0504048730321071 0.877623786997615 0.877623786997615
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Gpd1l ENSMUSG00000050627 0.968508090352874 0.968508090352874 0.8745646837132 0.968508090352874 0.791353022004223 0.968508090352874
Chpt1 ENSMUSG00000060002 0.865242889840744 0.927670415131274 0.448134380939566 0.927670415131274 0.927670415131274 0.927670415131274
Dgkd ENSMUSG00000070738 0.464917814653946 0.697376721980919 0.417966730338601 0.697376721980919 0.868348927285061 0.868348927285061
Ept1 ENSMUSG00000075703 0.285485700861786 0.856457102585359 0.899482015015846 0.899482015015846 0.840434267513807 0.899482015015846
PLA2G4B ENSMUSG00000098488 0.291048191351063 0.87314457405319 0.899503428156711 0.899503428156711 0.825074647057623 0.899503428156711

Central carbon metabolism in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Kit ENSMUSG00000005672 0.843522864090151 0.843522864090151 0.764189096979214 0.843522864090151 0.785324030328461 0.843522864090151
Pgam1 ENSMUSG00000011752 0.852801192111818 0.852801192111818 0.201046044735963 0.60313813420789 0.818870648703071 0.852801192111818
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Gls ENSMUSG00000026103 0.862052724029941 0.993702533374486 0.981097390127074 0.993702533374486 0.993702533374486 0.993702533374486
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Slc2a1 ENSMUSG00000028645 0.558933957546336 0.558933957546336 0.422520935465457 0.558933957546336 0.532652567018012 0.558933957546336
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Fgfr2 ENSMUSG00000030849 0.489052549868025 0.907465482402088 0.959059315824168 0.959059315824168 0.604976988268059 0.907465482402088
G6pdx ENSMUSG00000031400 0.635393278727122 0.924487728862621 0.924487728862621 0.924487728862621 0.564262605828105 0.924487728862621
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sirt6 ENSMUSG00000034748 0.198275859846668 0.594827579540004 0.83121063778572 0.83121063778572 0.74016838660268 0.83121063778572
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Slc7a5 ENSMUSG00000040010 0.924499173762329 0.924499173762329 0.397672524487893 0.924499173762329 0.78519793946658 0.924499173762329
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Gck ENSMUSG00000041798 0.740082185769287 0.763998372565369 0.731177852381581 0.763998372565369 0.763998372565369 0.763998372565369
Flt3 ENSMUSG00000042817 0.754636365931871 0.754636365931871 0.740030575439069 0.754636365931871 0.566068967758339 0.754636365931871
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ldha ENSMUSG00000063229 0.734233520650129 0.80362323615371 0.402157130181649 0.80362323615371 0.80362323615371 0.80362323615371

Hepatocellular carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt3 ENSMUSG00000000125 0.714481500581681 0.92230967493487 0.86734876587097 0.92230967493487 0.92230967493487 0.92230967493487
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Nqo1 ENSMUSG00000003849 0.852833338110102 0.852833338110102 0.740206742058971 0.852833338110102 0.734238148280686 0.852833338110102
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Bcl2l1 ENSMUSG00000007659 0.746191168970411 0.874557446877584 0.153856089929605 0.461568269788813 0.874557446877584 0.874557446877584
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Tert ENSMUSG00000021611 0.81582851704757 0.81582851704757 0.701754634531338 0.81582851704757 0.397594673419908 0.81582851704757
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Phf10 ENSMUSG00000023883 0.874277530135814 0.874277530135814 0.382457990746348 0.573686986119522 0.360005942232806 0.573686986119522
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Csnk1a1 ENSMUSG00000024576 0.346327182522591 0.91188749144334 0.806631502613227 0.91188749144334 0.91188749144334 0.91188749144334
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Smarca2 ENSMUSG00000024921 0.710572106549459 0.981104326013591 0.918239334645097 0.981104326013591 0.981104326013591 0.981104326013591
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Wnt2b ENSMUSG00000027840 0.873375253288832 0.873375253288832 0.462139546938377 0.873375253288832 0.823522346561903 0.873375253288832
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Wnt6 ENSMUSG00000033227 0.645708110911216 0.858593327573213 0.277065349389378 0.831196048168134 0.858593327573213 0.858593327573213
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Frat1 ENSMUSG00000067199 0.170247366619243 0.255371049928864 0.125509925421442 0.255371049928864 0.285775076922933 0.285775076922933
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Colorectal cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Bbc3 ENSMUSG00000002083 0.188734285867888 0.399170253207084 0.266113502138056 0.399170253207084 0.678358470961125 0.678358470961125
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Rala ENSMUSG00000008859 0.132136187857033 0.3964085635711 0.812792227354046 0.815861260968715 0.815861260968715 0.815861260968715
Msh3 ENSMUSG00000014850 0.896312893931429 0.959057445682841 0.53523630219468 0.959057445682841 0.959057445682841 0.959057445682841
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Msh2 ENSMUSG00000024151 0.604959112145457 0.874534811529155 0.274958891021396 0.824876673064189 0.874534811529155 0.874534811529155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Ralgds ENSMUSG00000026821 0.812804004429882 0.812804004429882 0.583105102689558 0.812804004429882 0.543088585547914 0.812804004429882
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Appl1 ENSMUSG00000040760 0.369582952258985 0.891020200193947 0.594013466795965 0.891020200193947 0.968512875540433 0.968512875540433
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Sphingolipid signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adora3 ENSMUSG00000000562 0.65761077159602 0.974786094925471 0.974786094925471 0.974786094925471 0.488579775744427 0.974786094925471
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Gab2 ENSMUSG00000004508 0.868287828848052 0.868287828848052 0.602160705619134 0.868287828848052 0.797435929075083 0.868287828848052
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Cers4 ENSMUSG00000008206 0.395559294446608 0.594006209468369 0.402192687740697 0.594006209468369 0.594006209468369 0.594006209468369
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rock2 ENSMUSG00000020580 0.205255555469948 0.615766666409843 0.695940548463652 0.955931174349073 0.955931174349073 0.955931174349073
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Ppp2r3c ENSMUSG00000021022 0.545632448057358 0.818448672086036 0.29469936421847 0.818448672086036 0.93393928372919 0.93393928372919
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Cers5 ENSMUSG00000023021 0.719131087733176 0.868349262275774 0.352523268181264 0.868349262275774 0.868349262275774 0.868349262275774
Abcc1 ENSMUSG00000023088 0.968518294477364 0.968518294477364 0.821998293564404 0.968518294477364 0.477083650629062 0.968518294477364
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Gnaq ENSMUSG00000024639 0.822005798248339 0.822005798248339 0.658382968346436 0.822005798248339 0.661235388260116 0.822005798248339
Cers6 ENSMUSG00000027035 0.574956904392998 0.644116340107808 0.610488122524972 0.644116340107808 0.644116340107808 0.644116340107808
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Nsmaf ENSMUSG00000028245 0.176976450509216 0.530929351527649 0.843559657603257 0.843559657603257 0.48942807929809 0.734142118947135
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Asah1 ENSMUSG00000031591 0.276670904113115 0.415006356169673 0.154802842133978 0.415006356169673 0.883904896414332 0.883904896414332
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Gnai2 ENSMUSG00000032562 0.764147302047563 0.828140918654959 0.302010370080407 0.828140918654959 0.828140918654959 0.828140918654959
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
S1pr1 ENSMUSG00000045092 0.618862693578404 0.618862693578404 0.424826674437993 0.618862693578404 0.408915300702995 0.618862693578404
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Map3k5 ENSMUSG00000071369 0.946505334041831 0.946505334041831 0.464790285810797 0.946505334041831 0.883889101846502 0.946505334041831

mTOR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt3 ENSMUSG00000000125 0.714481500581681 0.92230967493487 0.86734876587097 0.92230967493487 0.92230967493487 0.92230967493487
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Atp6v1f ENSMUSG00000004285 0.0690338633958723 0.207101590187617 0.222939063628633 0.33440859544295 0.496913393196454 0.496913393196454
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Slc3a2 ENSMUSG00000010095 0.893098108120501 0.933884966662735 0.179380437606304 0.538141312818913 0.933884966662735 0.933884966662735
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Nprl3 ENSMUSG00000020289 0.203702664069119 0.611107992207356 0.722382308562153 0.722382308562153 0.675532889963341 0.722382308562153
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Lpin1 ENSMUSG00000020593 0.395325022957911 0.592987534436867 0.23350601335978 0.592987534436867 0.877614220860537 0.877614220860537
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Telo2 ENSMUSG00000024170 0.30008590627972 0.900257718839159 0.716416485739769 0.943348767764004 0.943348767764004 0.943348767764004
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Rptor ENSMUSG00000025583 0.664108758918949 0.701783944724874 0.340784524476415 0.701783944724874 0.701783944724874 0.701783944724874
Wdr24 ENSMUSG00000025737 0.0413116303984237 0.123934891195271 0.32483174034334 0.32483174034334 0.21534725888783 0.323020888331744
Tti1 ENSMUSG00000027650 0.64411785793293 0.64411785793293 0.0291439630709458 0.0874318892128373 0.0708637964172076 0.106295694625811
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Wnt2b ENSMUSG00000027840 0.873375253288832 0.873375253288832 0.462139546938377 0.873375253288832 0.823522346561903 0.873375253288832
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Rps6 ENSMUSG00000028495 0.332453418387945 0.367177841714712 0.0428179702760643 0.128453910828193 0.367177841714712 0.367177841714712
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Flcn ENSMUSG00000032633 0.276517143972942 0.414775715959413 0.0997574634578557 0.299272390373567 0.834211485220143 0.834211485220143
Wnt6 ENSMUSG00000033227 0.645708110911216 0.858593327573213 0.277065349389378 0.831196048168134 0.858593327573213 0.858593327573213
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Depdc5 ENSMUSG00000037426 0.887011276666238 0.887011276666238 0.450420881006587 0.887011276666238 0.828115067084511 0.887011276666238
Slc7a5 ENSMUSG00000040010 0.924499173762329 0.924499173762329 0.397672524487893 0.924499173762329 0.78519793946658 0.924499173762329
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Mios ENSMUSG00000042447 0.794425526450263 0.987402692625264 0.566935300080862 0.987402692625264 0.987402692625264 0.987402692625264
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Strada ENSMUSG00000069631 0.616044905623391 0.749180724093663 0.749180724093663 0.749180724093663 0.661234749505122 0.749180724093663
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857

Non-small cell lung cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Eml4 ENSMUSG00000032624 0.896371834584113 0.962228079344828 0.962228079344828 0.962228079344828 0.669826704076083 0.962228079344828
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Rxrb ENSMUSG00000039656 0.155039132458621 0.232558698687931 0.0843535974343253 0.232558698687931 0.550982840393409 0.550982840393409
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346

Circadian rhythm

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cry1 ENSMUSG00000020038 0.334706187468492 0.502059281202738 0.273202938814424 0.502059281202738 0.681383714470333 0.681383714470333
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Rorc ENSMUSG00000028150 0.987404605541938 0.987404605541938 0.361207121735719 0.915784244713987 0.610522829809325 0.915784244713987
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Clock ENSMUSG00000029238 0.0203880833293266 0.0611642499879799 0.527463162530492 0.646980486603114 0.646980486603114 0.646980486603114
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Bhlhe40 ENSMUSG00000030103 0.514599687722255 0.771899531583382 0.818934458765151 0.818934458765151 0.504442479651251 0.771899531583382
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Arntl ENSMUSG00000055116 0.320809529086834 0.336393438222117 0.0156030380508408 0.0468091141525225 0.336393438222117 0.336393438222117
Per2 ENSMUSG00000055866 0.051056705122635 0.0765850576839526 0.0491730729723314 0.0765850576839526 0.890116537265103 0.890116537265103
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361

VEGF signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Nfatc2 ENSMUSG00000027544 0.905743330627905 0.930803033454725 0.655513435915049 0.930803033454725 0.930803033454725 0.930803033454725
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
PLA2G4B ENSMUSG00000098488 0.291048191351063 0.87314457405319 0.899503428156711 0.899503428156711 0.825074647057623 0.899503428156711

Vasopressin-regulated water reabsorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Vamp2 ENSMUSG00000020894 0.713533370673868 0.871452400328244 0.871452400328244 0.871452400328244 0.58854331361707 0.871452400328244
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Arhgdia ENSMUSG00000025132 0.422341226463687 0.63351183969553 0.300219684414466 0.63351183969553 0.752082591720677 0.752082591720677
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Creb3 ENSMUSG00000028466 0.324487693653349 0.714889048082817 0.476592698721878 0.714889048082817 0.924511841235858 0.924511841235858
Stx4a ENSMUSG00000030805 0.583114701383756 0.583114701383756 0.545715758505275 0.583114701383756 0.535245520817248 0.583114701383756
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138

Fc epsilon RI signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Gab2 ENSMUSG00000004508 0.868287828848052 0.868287828848052 0.602160705619134 0.868287828848052 0.797435929075083 0.868287828848052
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
PLA2G4B ENSMUSG00000098488 0.291048191351063 0.87314457405319 0.899503428156711 0.899503428156711 0.825074647057623 0.899503428156711

Insulin resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Mlxipl ENSMUSG00000005373 0.348830918104877 0.601943717986562 0.443172539970083 0.601943717986562 0.601943717986562 0.601943717986562
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Srebf1 ENSMUSG00000020538 0.0378624988392813 0.113587496517844 0.743151276644179 0.924508258653007 0.924508258653007 0.924508258653007
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Mgea5 ENSMUSG00000025220 0.346811164869063 0.687058841623263 0.687058841623263 0.687058841623263 0.618675937670564 0.687058841623263
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Ptpn1 ENSMUSG00000027540 0.574931513764371 0.915126943884423 0.770209866679489 0.915126943884423 0.915126943884423 0.915126943884423
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Slc27a3 ENSMUSG00000027932 0.91827394392113 0.91827394392113 0.574999596604177 0.862499394906265 0.457689367381083 0.862499394906265
Creb3 ENSMUSG00000028466 0.324487693653349 0.714889048082817 0.476592698721878 0.714889048082817 0.924511841235858 0.924511841235858
Slc2a1 ENSMUSG00000028645 0.558933957546336 0.558933957546336 0.422520935465457 0.558933957546336 0.532652567018012 0.558933957546336
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Ptprf ENSMUSG00000033295 0.519575906867502 0.877666014009073 0.877666014009073 0.877666014009073 0.803587652118962 0.877666014009073
Ppargc1b ENSMUSG00000033871 0.915122287962798 0.915122287962798 0.243165227415001 0.729495682245002 0.89011075615628 0.915122287962798
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
G6pc3 ENSMUSG00000034793 0.175411584724297 0.263117377086445 0.124108250719009 0.263117377086445 0.96534228681455 0.96534228681455
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Ppp2r4 ENSMUSG00000039515 0.205304004392798 0.307956006589197 0.0405761065988622 0.121728319796587 0.630021202158129 0.630021202158129
Ppp1ca ENSMUSG00000040385 0.146984170341655 0.220476255512483 0.0121365677036429 0.0364097031109288 0.550760247056706 0.550760247056706
Pck2 ENSMUSG00000040618 0.257893691186856 0.386840536780284 0.201052471017059 0.386840536780284 0.812767660690678 0.812767660690678
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Acacb ENSMUSG00000042010 0.601592849200848 0.710101477393061 0.233677746371738 0.701033239115215 0.710101477393061 0.710101477393061
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Slc27a4 ENSMUSG00000059316 0.641310033271721 0.943364027499691 0.251305815678121 0.753917447034362 0.943364027499691 0.943364027499691
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Ppp1r3e ENSMUSG00000072494 0.887016765495874 0.984256638411033 0.630038105509531 0.984256638411033 0.984256638411033 0.984256638411033

Oocyte meiosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Rec8 ENSMUSG00000002324 0.0901835555477735 0.27055066664332 0.87765873520601 0.87765873520601 0.307624200065091 0.461436300097637
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Cpeb4 ENSMUSG00000020300 0.686957351062637 0.686957351062637 0.103957545050572 0.311872635151715 0.499034837436688 0.686957351062637
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Cdc23 ENSMUSG00000024370 0.971648137380663 0.971648137380663 0.937075055671036 0.971648137380663 0.464625309234362 0.971648137380663
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Slk ENSMUSG00000025060 0.191395289221441 0.574185867664322 0.962229061152698 0.962229061152698 0.652612926022816 0.962229061152698
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Mad2l2 ENSMUSG00000029003 0.0163341725967249 0.0490025177901746 0.211013925138425 0.316520887707637 0.794360760642728 0.794360760642728
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Stag3 ENSMUSG00000036928 0.902536762738612 0.902536762738612 0.779012817704451 0.902536762738612 0.241019158805975 0.723057476417924
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ppp1ca ENSMUSG00000040385 0.146984170341655 0.220476255512483 0.0121365677036429 0.0364097031109288 0.550760247056706 0.550760247056706
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Fbxo43 ENSMUSG00000048230 0.373955177995753 0.47406488829001 0.47406488829001 0.47406488829001 0.151176963622411 0.453530890867234
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932

EGFR tyrosine kinase inhibitor resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Bcl2l1 ENSMUSG00000007659 0.746191168970411 0.874557446877584 0.153856089929605 0.461568269788813 0.874557446877584 0.874557446877584
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Rps6 ENSMUSG00000028495 0.332453418387945 0.367177841714712 0.0428179702760643 0.128453910828193 0.367177841714712 0.367177841714712
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Fgfr2 ENSMUSG00000030849 0.489052549868025 0.907465482402088 0.959059315824168 0.959059315824168 0.604976988268059 0.907465482402088
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

FoxO signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Homer3 ENSMUSG00000003573 0.971664825003025 0.971664825003025 0.740207693036197 0.971664825003025 0.933940888356251 0.971664825003025
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Nlk ENSMUSG00000017376 0.770180152451643 0.927660812353485 0.280306331636382 0.840918994909145 0.927660812353485 0.927660812353485
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Crebbp ENSMUSG00000022521 0.159702566230389 0.265458106843743 0.176972071229162 0.265458106843743 0.773227837782496 0.773227837782496
Usp7 ENSMUSG00000022710 0.514512015356096 0.924508754862752 0.905745698323521 0.924508754862752 0.924508754862752 0.924508754862752
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Atg12 ENSMUSG00000032905 0.399989119756591 0.943367739510359 0.743193874058818 0.943367739510359 0.943367739510359 0.943367739510359
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
G6pc3 ENSMUSG00000034793 0.175411584724297 0.263117377086445 0.124108250719009 0.263117377086445 0.96534228681455 0.96534228681455
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Fbxo25 ENSMUSG00000038365 0.862123830145667 0.96222791078642 0.96222791078642 0.96222791078642 0.725328370802636 0.96222791078642
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Pck2 ENSMUSG00000040618 0.257893691186856 0.386840536780284 0.201052471017059 0.386840536780284 0.812767660690678 0.812767660690678
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
S1pr1 ENSMUSG00000045092 0.618862693578404 0.618862693578404 0.424826674437993 0.618862693578404 0.408915300702995 0.618862693578404
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Cdkn2d ENSMUSG00000096472 0.246335950338178 0.411080637724506 0.411080637724506 0.411080637724506 0.402207804417436 0.411080637724506

ErbB signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Rps6kb1 ENSMUSG00000020516 0.0482529780998285 0.0723794671497428 0.0339702830615557 0.0723794671497428 0.962228344819744 0.962228344819744
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Bad ENSMUSG00000024959 0.455215547981104 0.664038816947298 0.206744372543848 0.620233117631545 0.664038816947298 0.664038816947298
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Nras ENSMUSG00000027852 0.342737445071547 0.87144949762898 0.740212335892776 0.87144949762898 0.87144949762898 0.87144949762898
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Nck2 ENSMUSG00000066877 0.695886060438501 0.773225423434546 0.393349353627609 0.773225423434546 0.773225423434546 0.773225423434546

N-Glycan biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Man1a2 ENSMUSG00000008763 0.330822217752787 0.877668439988077 0.71351773942311 0.877668439988077 0.877668439988077 0.877668439988077
Fut8 ENSMUSG00000021065 0.800516224830663 0.933931185203149 0.933931185203149 0.933931185203149 0.504470362618556 0.933931185203149
Dpm2 ENSMUSG00000026810 0.324494861834532 0.50685771288579 0.50685771288579 0.50685771288579 0.365213878733351 0.50685771288579
Rpn2 ENSMUSG00000027642 0.179436828154619 0.269155242231929 0.011784676199902 0.0353540285997061 0.618814128863571 0.618814128863571
Glt28d2 ENSMUSG00000031286 0.831144980850077 0.949621753864074 0.949621753864074 0.949621753864074 0.678099586980704 0.949621753864074
Alg9 ENSMUSG00000032059 0.865216430727327 0.865216430727327 0.0872328677294176 0.261698603188253 0.728305688303467 0.865216430727327
Alg3 ENSMUSG00000033809 0.0337267523379115 0.0545486602768248 0.0363657735178832 0.0545486602768248 0.454677354933429 0.454677354933429
Mgat5 ENSMUSG00000036155 0.61329363619444 0.927676688706274 0.927676688706274 0.927676688706274 0.773241361632843 0.927676688706274
Man1b1 ENSMUSG00000036646 0.283689527918357 0.425534291877536 0.19681710962553 0.425534291877536 0.97165506986786 0.97165506986786
Alg1 ENSMUSG00000039427 0.238169764923128 0.238169764923128 0.0288573539356085 0.0865720618068256 0.213940154501969 0.238169764923128
Alg13 ENSMUSG00000041718 0.577688082487925 0.92140557181144 0.92140557181144 0.92140557181144 0.641319050198082 0.92140557181144
Mgat3 ENSMUSG00000042428 0.71051193942017 0.868328196580792 0.28201811576586 0.846054347297579 0.868328196580792 0.868328196580792
B4galt3 ENSMUSG00000052423 0.555852678813415 0.833779018220122 0.981105507625407 0.981105507625407 0.481717689407786 0.833779018220122
Alg11 ENSMUSG00000063362 0.0794420155608323 0.238326046682497 0.312884692417225 0.469327038625838 0.843435667031689 0.843435667031689
Alg6 ENSMUSG00000073792 0.968509806380037 0.968509806380037 0.902606179045671 0.968509806380037 0.548297525238618 0.968509806380037
Dolk ENSMUSG00000075419 0.0148011689873284 0.0148011689873284 2.65654703682613e-05 7.96964111047838e-05 0.0119531327006982 0.0148011689873284
Alg10b ENSMUSG00000075470 0.0312481145217792 0.0937443435653377 0.191326686546626 0.286990029819939 0.893213846900112 0.893213846900112
Dpm1 ENSMUSG00000078919 0.0409862603823654 0.0614793905735481 0.0180882720006123 0.0542648160018368 0.937087214004604 0.937087214004604

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Rarg ENSMUSG00000001288 0.0949507440318001 0.2848522320954 0.577661162633673 0.86649174395051 0.937080448558437 0.937080448558437
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Taco1 ENSMUSG00000001983 0.086484862945857 0.259454588837571 0.815861281163154 0.815861281163154 0.528925419338586 0.793388129007879
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Supt6 ENSMUSG00000002052 0.918249683822428 0.921384615446289 0.509525588181232 0.921384615446289 0.921384615446289 0.921384615446289
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Med6 ENSMUSG00000002679 0.990552165598131 0.990552165598131 0.558936418167482 0.990552165598131 0.672681426758166 0.990552165598131
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Med25 ENSMUSG00000002968 0.971653838289879 0.971653838289879 0.908873487166612 0.971653838289879 0.4670905839486 0.971653838289879
Cdk12 ENSMUSG00000003119 0.755162148087285 0.93394600324458 0.67272885843545 0.93394600324458 0.93394600324458 0.93394600324458
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Zfp81 ENSMUSG00000003929 0.921398276173297 0.921398276173297 0.450420982394875 0.921398276173297 0.865197012496934 0.921398276173297
Dnmt1 ENSMUSG00000004099 0.577555858074608 0.635538036514718 0.457685292289755 0.635538036514718 0.635538036514718 0.635538036514718
Zfp324 ENSMUSG00000004500 0.927677083266821 0.927677083266821 0.734248202546478 0.927677083266821 0.716448379206918 0.927677083266821
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Trim28 ENSMUSG00000005566 0.0696552212572158 0.208965663771647 0.149279783577451 0.223919675366176 0.56151364795391 0.56151364795391
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ctcf ENSMUSG00000005698 0.481928119997173 0.880785231141268 0.880785231141268 0.880785231141268 0.868318228371637 0.880785231141268
Nr2c2 ENSMUSG00000005893 0.764183193354547 0.877616202117077 0.74011847951785 0.877616202117077 0.877616202117077 0.877616202117077
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ttc5 ENSMUSG00000006288 0.289245761101568 0.797531873832735 0.797531873832735 0.797531873832735 0.591266864698899 0.797531873832735
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Rbm14 ENSMUSG00000006456 0.208168357957752 0.569522474062835 0.504457351146993 0.569522474062835 0.569522474062835 0.569522474062835
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Phax ENSMUSG00000008301 0.593994621681469 0.890991932522203 0.299988765429107 0.890991932522203 0.908834658280149 0.908834658280149
Pou2f2 ENSMUSG00000008496 0.78440929149125 0.799568301739656 0.713183887624394 0.799568301739656 0.799568301739656 0.799568301739656
Hipk1 ENSMUSG00000008730 0.0940924963949365 0.28227748918481 0.713539120862588 0.713539120862588 0.684230035763789 0.713539120862588
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Zfp790 ENSMUSG00000011427 0.08725095874565 0.26175287623695 0.431745151093074 0.53262732242229 0.53262732242229 0.53262732242229
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Med15 ENSMUSG00000012114 0.821919378323644 0.893214949965843 0.710574761934654 0.893214949965843 0.893214949965843 0.893214949965843
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Surf1 ENSMUSG00000015790 0.440974576923634 0.661461865385452 0.666963880398388 0.666963880398388 0.422383519581425 0.661461865385452
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Gtf3a ENSMUSG00000016503 0.101848345269951 0.152772517904927 0.0141417890799713 0.0424253672399139 0.977930494027345 0.977930494027345
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Med1 ENSMUSG00000018160 0.176912994511997 0.530738983535992 0.937088643933494 0.937088643933494 0.690096905754397 0.937088643933494
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Zkscan6 ENSMUSG00000018347 0.291057114673061 0.687202073468259 0.678505412905333 0.687202073468259 0.687202073468259 0.687202073468259
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Yeats4 ENSMUSG00000020171 0.658173758986959 0.933918552920911 0.238351538159865 0.715054614479596 0.933918552920911 0.933918552920911
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Polrmt ENSMUSG00000020329 0.0226721096891373 0.0680163290674118 0.0482143659156162 0.0723215488734243 0.713486836473952 0.713486836473952
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Med7 ENSMUSG00000020397 0.728213913004377 0.858987230162626 0.203769079948581 0.611307239845742 0.858987230162626 0.858987230162626
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Ppm1d ENSMUSG00000020525 0.624435190288112 0.794447909549847 0.794447909549847 0.794447909549847 0.585774454653853 0.794447909549847
Cox11 ENSMUSG00000020544 0.0434338691683981 0.0651508037525971 1.83822333159272e-06 5.51466999477816e-06 0.324900544328719 0.324900544328719
Dnmt3a ENSMUSG00000020661 0.695929769387012 0.871446110897976 0.86214080855387 0.871446110897976 0.871446110897976 0.871446110897976
Rffl ENSMUSG00000020696 0.499406497178666 0.569551782735742 0.309533365572562 0.569551782735742 0.569551782735742 0.569551782735742
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Med31 ENSMUSG00000020801 0.613191476590519 0.871411388586427 0.871411388586427 0.871411388586427 0.438725432334298 0.871411388586427
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Ppp1r13b ENSMUSG00000021285 0.707638838245221 0.785353922376112 0.785353922376112 0.785353922376112 0.779270489867307 0.785353922376112
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
A530054K11Rik ENSMUSG00000021510 0.079401470788274 0.121062123721737 0.0807080824811581 0.121062123721737 0.725217096412423 0.725217096412423
Med10 ENSMUSG00000021598 0.915124101313431 0.915124101313431 0.912007984588996 0.915124101313431 0.537724386371694 0.915124101313431
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ints9 ENSMUSG00000021975 0.883848910566009 0.883848910566009 0.215446663437689 0.646339990313066 0.669771745593722 0.883848910566009
Med4 ENSMUSG00000022109 0.594007900130456 0.891011850195685 0.208123102342938 0.624369307028813 0.965367834542043 0.965367834542043
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Zfp263 ENSMUSG00000022529 0.855866014430946 1 0.588496132615472 1 1 1
Rrn3 ENSMUSG00000022682 0.624339904317712 0.834266910855487 0.344792065919548 0.834266910855487 0.834266910855487 0.834266910855487
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Tarbp2 ENSMUSG00000023051 0.008972884631416 0.026918653894248 0.215388230370671 0.323082345556007 0.67841067518176 0.67841067518176
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Taf8 ENSMUSG00000023980 0.828124441516432 0.828124441516432 0.271482342300993 0.748921555648755 0.49928103709917 0.748921555648755
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Phf1 ENSMUSG00000024193 0.764186439125127 0.764186439125127 0.704721021982229 0.764186439125127 0.607738058242616 0.764186439125127
Mllt1 ENSMUSG00000024212 0.974811565183814 0.974811565183814 0.543035961218538 0.974811565183814 0.837368583319366 0.974811565183814
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Epc1 ENSMUSG00000024240 0.16573552702746 0.497206581082381 0.393337278290945 0.590005917436418 0.632780075332655 0.632780075332655
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Zfp871 ENSMUSG00000024298 0.0398045680509124 0.119413704152737 0.0949677760423197 0.14245166406348 0.770224083518563 0.770224083518563
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Iws1 ENSMUSG00000024384 0.613303748580275 0.613303748580275 0.469731250453748 0.613303748580275 0.59672817939277 0.613303748580275
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Pcgf6 ENSMUSG00000025050 0.758178056805396 0.946510665533973 0.716486625058548 0.946510665533973 0.946510665533973 0.946510665533973
Ints4 ENSMUSG00000025133 0.63555889649176 0.63555889649176 0.397770259228666 0.596655388842999 0.127894607161556 0.383683821484669
Ldb1 ENSMUSG00000025223 0.410968262589304 0.862094308754716 0.862094308754716 0.862094308754716 0.577562753134684 0.862094308754716
Tbl1x ENSMUSG00000025246 0.949633171970116 0.990551854325694 0.782226920895053 0.990551854325694 0.990551854325694 0.990551854325694
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Banp ENSMUSG00000025316 0.352973634799885 0.352973634799885 0.0550155669365745 0.165046700809724 0.313355013846564 0.352973634799885
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Nabp2 ENSMUSG00000025374 0.880731820019853 0.880731820019853 0.731275523020539 0.880731820019853 0.467153715493259 0.880731820019853
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Zfp202 ENSMUSG00000025602 0.232141296260803 0.693007696821341 0.693007696821341 0.693007696821341 0.572234447202385 0.693007696821341
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Zfp282 ENSMUSG00000025821 0.86520171122549 0.974808871158847 0.809701439928137 0.974808871158847 0.974808871158847 0.974808871158847
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Gls ENSMUSG00000026103 0.862052724029941 0.993702533374486 0.981097390127074 0.993702533374486 0.993702533374486 0.993702533374486
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Tsn ENSMUSG00000026374 0.588541396682904 0.728316589011037 0.330792910053038 0.728316589011037 0.728316589011037 0.728316589011037
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Med27 ENSMUSG00000026799 0.188742580635213 0.283113870952819 0.130086868464712 0.283113870952819 0.380314155487782 0.380314155487782
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Gtf3c5 ENSMUSG00000026816 0.240001081265092 0.360001621897639 0.209608182047211 0.360001621897639 0.8036268665289 0.8036268665289
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Notch1 ENSMUSG00000026923 0.322985784663396 0.669767231045251 0.669767231045251 0.669767231045251 0.489406609204599 0.669767231045251
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Tbl1xr1 ENSMUSG00000027630 0.486940143036373 0.730410214554559 0.380216907855341 0.730410214554559 0.971661244333188 0.971661244333188
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Rprd1b ENSMUSG00000027651 0.987403179376432 0.987403179376432 0.0127720652161165 0.0383161956483495 0.773218081372242 0.987403179376432
Skil ENSMUSG00000027660 0.0918417107601723 0.275525132280517 0.577695864050358 0.57769637430179 0.57769637430179 0.57769637430179
Ints3 ENSMUSG00000027933 0.812771540280415 0.92451428819997 0.116488043451683 0.34946413035505 0.92451428819997 0.92451428819997
Rprd2 ENSMUSG00000028106 0.499429620793092 0.955939609127718 0.908882118075782 0.955939609127718 0.955939609127718 0.955939609127718
Ccnc ENSMUSG00000028252 0.173136755541683 0.519410266625048 0.474582473879636 0.711873710819454 0.797518469681053 0.797518469681053
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Cpsf3l ENSMUSG00000029034 0.23996748249015 0.359951223735224 0.0865341636468342 0.259602490940503 0.406629341484474 0.406629341484474
Ssu72 ENSMUSG00000029038 0.136242829605009 0.204364244407513 0.0504278103517965 0.151283431055389 0.743144881051361 0.743144881051361
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Nrbp1 ENSMUSG00000029148 0.921403988638114 1 1 1 0.269837366248565 0.809512098745694
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Mtf2 ENSMUSG00000029267 0.883894006962258 0.930811495601107 0.499428517456142 0.930811495601107 0.930811495601107 0.930811495601107
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Zfp12 ENSMUSG00000029587 0.422465897532989 0.912008816289995 0.740157948518281 0.912008816289995 0.912008816289995 0.912008816289995
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Cdk8 ENSMUSG00000029635 0.846634306273708 0.846634306273708 0.746156018411803 0.846634306273708 0.652647960471599 0.846634306273708
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Aebp2 ENSMUSG00000030232 0.977953534107396 0.981104927397305 0.399951668653518 0.981104927397305 0.981104927397305 0.981104927397305
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Zfp606 ENSMUSG00000030386 0.687193336158729 0.81892925311892 0.313342433084137 0.81892925311892 0.81892925311892 0.81892925311892
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Zfp626 ENSMUSG00000030604 0.746171241161978 0.955937633582514 0.955937633582514 0.955937633582514 0.359155367155075 0.955937633582514
Tead2 ENSMUSG00000030796 0.902596998516483 0.921382103057572 0.550973178937966 0.921382103057572 0.921382103057572 0.921382103057572
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
G6pdx ENSMUSG00000031400 0.635393278727122 0.924487728862621 0.924487728862621 0.924487728862621 0.564262605828105 0.924487728862621
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Zfp90 ENSMUSG00000031907 0.883903287645641 0.883903287645641 0.704719387396106 0.883903287645641 0.543083039876083 0.883903287645641
Maml2 ENSMUSG00000031925 0.877637040192188 0.877637040192188 0.843497733680374 0.877637040192188 0.344585874854108 0.877637040192188
Med17 ENSMUSG00000031935 0.773233922582795 0.773233922582795 0.75215585817309 0.773233922582795 0.66981399974883 0.773233922582795
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Tcf12 ENSMUSG00000032228 0.18608468481739 0.420199050336649 0.322980092384098 0.420199050336649 0.420199050336649 0.420199050336649
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Gtf3c1 ENSMUSG00000032777 0.514477384975409 0.771716077463113 0.326830323471223 0.771716077463113 0.990549428512413 0.990549428512413
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Rpap2 ENSMUSG00000033773 0.955928538716565 0.955928538716565 0.469746652759616 0.955928538716565 0.728234247481334 0.955928538716565
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Mga ENSMUSG00000033943 0.247957790892636 0.603307914405705 0.40220527627047 0.603307914405705 0.632801060084072 0.632801060084072
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Zfp944 ENSMUSG00000033972 0.209644304089903 0.566914450263349 0.411112217202674 0.566914450263349 0.566914450263349 0.566914450263349
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Zfp418 ENSMUSG00000034538 0.14268551345265 0.214028270178975 0.142652524867088 0.214028270178975 0.627237966620823 0.627237966620823
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Zfp661 ENSMUSG00000034800 0.477089366826772 0.575003228483636 0.292885080548305 0.575003228483636 0.575003228483636 0.575003228483636
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Ints6 ENSMUSG00000035161 0.148221007726829 0.444663023180488 0.602217565222341 0.773230202783295 0.773230202783295 0.773230202783295
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Cox18 ENSMUSG00000035505 0.388966256857858 0.583449385286787 0.0631197324422958 0.189359197326887 0.770219768862008 0.770219768862008
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Gtf3c4 ENSMUSG00000035666 0.984256165622295 0.984256165622295 0.162099658146484 0.486298974439453 0.921405886685337 0.984256165622295
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Ago2 ENSMUSG00000036698 0.481894144503412 0.987402845972038 0.846656056497879 0.987402845972038 0.987402845972038 0.987402845972038
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Zfp157 ENSMUSG00000036898 0.737229317287235 0.874542761003085 0.22739896474232 0.68219689422696 0.874542761003085 0.874542761003085
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Jarid2 ENSMUSG00000038518 0.548288848244042 0.959079459598398 0.937083814027261 0.959079459598398 0.959079459598398 0.959079459598398
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Med30 ENSMUSG00000038622 0.974812698215822 0.974812698215822 0.527451989710235 0.974812698215822 0.949651629146872 0.974812698215822
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Rbpj ENSMUSG00000039191 0.855923261172793 0.855923261172793 0.54306369608504 0.846381237030571 0.564254158020381 0.846381237030571
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Rxrb ENSMUSG00000039656 0.155039132458621 0.232558698687931 0.0843535974343253 0.232558698687931 0.550982840393409 0.550982840393409
Cited2 ENSMUSG00000039910 0.296426512311656 0.296426512311656 0.236651113528526 0.296426512311656 0.261261147442375 0.296426512311656
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Ipo8 ENSMUSG00000040029 0.481680727560799 0.737621428063108 0.491747618708739 0.737621428063108 0.809596030569435 0.809596030569435
Asun ENSMUSG00000040250 0.572283795940274 0.73127494591286 0.309570181456686 0.73127494591286 0.73127494591286 0.73127494591286
Zfp770 ENSMUSG00000040321 0.0421790568296861 0.126537170489058 0.921360891350043 0.921360891350043 0.815769388332954 0.921360891350043
Mybbp1a ENSMUSG00000040463 0.155944840891198 0.32543444708292 0.21695629805528 0.32543444708292 0.824940780129597 0.824940780129597
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Ints8 ENSMUSG00000040738 0.191439387267038 0.574318161801113 0.949646823023688 0.990553161463228 0.990553161463228 0.990553161463228
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cdk13 ENSMUSG00000041297 0.350848580104832 0.89949118258729 0.788318112038651 0.89949118258729 0.89949118258729 0.89949118258729
Gtf3c3 ENSMUSG00000041303 0.482006439491822 0.704726334199839 0.212555196216459 0.637665588649376 0.704726334199839 0.704726334199839
Ago1 ENSMUSG00000041530 0.924502000524229 0.924502000524229 0.918254215470046 0.924502000524229 0.740051340943326 0.924502000524229
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Zfp386 ENSMUSG00000042063 0.719407853271497 0.719407853271497 0.0173090693496571 0.0519272080489714 0.649794999527396 0.719407853271497
Kdm5b ENSMUSG00000042207 0.797529374580581 0.905741884779121 0.43164088085525 0.905741884779121 0.905741884779121 0.905741884779121
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Ago4 ENSMUSG00000042500 0.661114457350717 0.940210895276645 0.828130337550788 0.940210895276645 0.940210895276645 0.940210895276645
Zfp784 ENSMUSG00000043290 0.102220206720847 0.306660620162542 0.509524073190022 0.764286109785034 0.883887904440387 0.883887904440387
Lsm11 ENSMUSG00000044847 0.436363548388505 0.654545322582758 0.219769748508287 0.654545322582758 0.692921430693931 0.692921430693931
Med26 ENSMUSG00000045248 0.852810083936291 0.871444332045489 0.445628277225206 0.871444332045489 0.871444332045489 0.871444332045489
Zfp688 ENSMUSG00000045251 0.0510429928638419 0.153128978591526 0.472043217252454 0.708064825878682 0.86517801866064 0.86517801866064
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Zfp740 ENSMUSG00000046897 0.215460677507988 0.646382032523965 0.558932463577806 0.834310029896056 0.834310029896056 0.834310029896056
Zfp445 ENSMUSG00000047036 0.382279221650018 0.573418832475027 0.182056555164653 0.546169665493958 0.834248971157118 0.834248971157118
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Tnrc6b ENSMUSG00000047888 0.746186023227431 0.746186023227431 0.704714294857786 0.746186023227431 0.64982873699181 0.746186023227431
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Zfp738 ENSMUSG00000048280 0.348832321796375 0.511999101472343 0.0786801495968421 0.236040448790526 0.511999101472343 0.511999101472343
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Zfp689 ENSMUSG00000048921 0.746161823092674 0.746161823092674 0.646960744142472 0.746161823092674 0.519698243563037 0.746161823092674
Prmt6 ENSMUSG00000049300 0.965374627946491 0.981108445923553 0.616073215983192 0.981108445923553 0.981108445923553 0.981108445923553
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806
Zfp668 ENSMUSG00000049728 0.728318017081463 0.977954253101518 0.977954253101518 0.977954253101518 0.548222725753309 0.977954253101518
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Zfp61 ENSMUSG00000050605 0.728255393999416 0.80972891649625 0.296433823886353 0.80972891649625 0.80972891649625 0.80972891649625
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Zfp169 ENSMUSG00000050954 0.225956461911946 0.338934692867919 0.151599034348063 0.338934692867919 0.9653745468202 0.9653745468202
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Zfp961 ENSMUSG00000052446 0.313345469879295 0.51343843204474 0.342292288029827 0.51343843204474 0.537618763610479 0.537618763610479
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Tnrc6a ENSMUSG00000052707 0.843558416051339 0.843558416051339 0.408919705164051 0.843558416051339 0.773228059504463 0.843558416051339
Zfp212 ENSMUSG00000052763 0.0933273760001477 0.279982128000443 0.276778316078644 0.415167474117966 0.646917019555695 0.646917019555695
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Yap1 ENSMUSG00000053110 0.180814967855615 0.271222451783422 0.0226891810822577 0.0680675432467731 0.632849896559277 0.632849896559277
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Zfp952 ENSMUSG00000053390 0.984257221868525 0.984257221868525 0.448158705547278 0.984257221868525 0.788397649478662 0.984257221868525
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Zfp867 ENSMUSG00000054519 0.00135825115299108 0.00407475345897325 0.434055483426102 0.434055483426102 0.141618529549119 0.212427794323679
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Zfp78 ENSMUSG00000055150 0.26627947686516 0.472921574890155 0.31528104992677 0.472921574890155 0.669832326835454 0.669832326835454
Zfp101 ENSMUSG00000055240 0.734262482213761 0.734262482213761 0.594012848288838 0.734262482213761 0.556278619594594 0.734262482213761
Zfp457 ENSMUSG00000055341 0.930746361961035 0.930746361961035 0.469074828413572 0.930746361961035 0.680944397078772 0.930746361961035
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Zfp459 ENSMUSG00000055560 0.890135106257556 0.911994958053049 0.874544220095528 0.911994958053049 0.911994958053049 0.911994958053049
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Zkscan5 ENSMUSG00000055991 0.767196870167699 0.974810879105003 0.974810879105003 0.974810879105003 0.257929357432216 0.773788072296648
Zfp709 ENSMUSG00000056019 0.797521765668082 0.797521765668082 0.443426304833404 0.797521765668082 0.791439214671057 0.797521765668082
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Zfp658 ENSMUSG00000056592 0.228914595980664 0.529448402085402 0.352965601390268 0.529448402085402 0.740145018102158 0.740145018102158
Zfp180 ENSMUSG00000057101 0.635672883009121 0.716491563767633 0.50699756826521 0.716491563767633 0.716491563767633 0.716491563767633
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Zfp759 ENSMUSG00000057396 0.170558669666104 0.255838004499155 0.0613950170147065 0.184185051044119 0.716464382522481 0.716464382522481
Zfp317 ENSMUSG00000057551 0.955937432081627 0.955937432081627 0.350911493675258 0.919893453908227 0.613262302605485 0.919893453908227
Zfp746 ENSMUSG00000057691 0.716416334129172 0.91511973774182 0.690105046205586 0.91511973774182 0.91511973774182 0.91511973774182
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Zfp420 ENSMUSG00000058402 0.155023950321555 0.465071850964665 0.56424187734588 0.56424187734588 0.371750809395157 0.557626214092735
Max ENSMUSG00000059436 0.722392653421377 0.930812666801164 0.855938138929478 0.930812666801164 0.930812666801164 0.930812666801164
Zfp426 ENSMUSG00000059475 0.219940486145568 0.545696630321519 0.545696630321519 0.545696630321519 0.524863157898077 0.545696630321519
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Zfp874b ENSMUSG00000059839 0.0310173143234376 0.0930519429703127 0.42943013546867 0.644145203203005 0.794479238099772 0.794479238099772
Zfp74 ENSMUSG00000059975 0.74312652221704 0.846609686576337 0.846609686576337 0.846609686576337 0.610487324547613 0.846609686576337
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Zfp937 ENSMUSG00000060336 0.50693038776156 0.52223685668885 0.371587959673858 0.52223685668885 0.52223685668885 0.52223685668885
Maml3 ENSMUSG00000061143 0.734134168310536 0.828152725615866 0.828152725615866 0.828152725615866 0.752082162914131 0.828152725615866
Zfp873 ENSMUSG00000061371 0.725355719425837 0.902625754780667 0.902625754780667 0.902625754780667 0.296514941101917 0.88954482330575
Zfp229 ENSMUSG00000061544 0.675617394576195 0.788380161701511 0.788380161701511 0.788380161701511 0.153832893418283 0.46149868025485
Zfp954 ENSMUSG00000062116 0.658369028217264 0.959082992771107 0.959081970344945 0.959082992771107 0.959082992771107 0.959082992771107
Zfp706 ENSMUSG00000062397 0.190066273777015 0.285099410665523 0.018087075658525 0.0542612269755749 0.837366899643581 0.837366899643581
Zfp398 ENSMUSG00000062519 0.564185686622195 0.877651726266627 0.849742320769921 0.877651726266627 0.877651726266627 0.877651726266627
Zfp28 ENSMUSG00000062861 0.486832734119497 0.803632902387604 0.803632902387604 0.803632902387604 0.624360129581231 0.803632902387604
Zfp780b ENSMUSG00000063047 0.39107661533431 0.467333115705241 0.467333115705241 0.467333115705241 0.34277150669525 0.467333115705241
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Zfp35 ENSMUSG00000063281 0.115441460058477 0.346324380175432 0.499295440472368 0.748943160708552 0.837307669061056 0.837307669061056
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Zkscan8 ENSMUSG00000063894 0.755157435922603 0.755157435922603 0.280297057034039 0.63035178324964 0.420234522166427 0.63035178324964
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Med14 ENSMUSG00000064127 0.159665944223733 0.4789978326712 0.896381429694953 0.896381429694953 0.740156213379708 0.896381429694953
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Zfp932 ENSMUSG00000066613 0.959072162115386 0.959072162115386 0.519630290172417 0.959072162115386 0.752175376007337 0.959072162115386
Zfp617 ENSMUSG00000066880 0.268096534148183 0.402144801222275 0.108317010074898 0.324951030224694 0.583011859976807 0.583011859976807
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Zfp760 ENSMUSG00000067928 0.48687582265191 0.548295288947333 0.522226293473166 0.548295288947333 0.548295288947333 0.548295288947333
Zfp948 ENSMUSG00000067931 0.0285453743051351 0.0856361229154051 0.195421754963501 0.293132632445251 0.937089239708422 0.937089239708422
Zfp160 ENSMUSG00000067942 0.924541399094157 0.924541399094157 0.249662670833093 0.748988012499278 0.610522750033069 0.915784125049603
Zfp442 ENSMUSG00000068130 0.334710899073492 0.502066348610238 0.178194264925847 0.502066348610238 0.537804113289125 0.537804113289125
Zfp120 ENSMUSG00000068134 0.828151554474058 0.828151554474058 0.445754607281558 0.828151554474058 0.825056118712257 0.828151554474058
Zfp467 ENSMUSG00000068551 0.672505367288898 0.701629588633727 0.701629588633727 0.701629588633727 0.106981150107606 0.320943450322817
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Gm5595 ENSMUSG00000069727 0.150466132955774 0.225699199433661 0.0696380933388098 0.208914280016429 0.737238389965789 0.737238389965789
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Zscan25 ENSMUSG00000070420 0.162071713401021 0.486215140203062 0.737235846318888 0.737235846318888 0.572289335338048 0.737235846318888
1700049G17Rik ENSMUSG00000070709 0.684297290588225 0.74319910385997 0.328836522252172 0.74319910385997 0.74319910385997 0.74319910385997
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Zfp213 ENSMUSG00000071256 0.448148041703337 0.672709536904298 0.672709536904298 0.672709536904298 0.5589248616806 0.672709536904298
Zfp942 ENSMUSG00000071267 0.0413590765633997 0.124077229690199 0.106407235061891 0.159610852592837 0.643989625953818 0.643989625953818
Zfp71-rs1 ENSMUSG00000071281 0.320955744765794 0.43629926817455 0.252950895013197 0.43629926817455 0.43629926817455 0.43629926817455
Ints5 ENSMUSG00000071652 0.34473034700903 0.517095520513545 0.115495177311501 0.346485531934502 0.782297835248887 0.782297835248887
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153
Rybp ENSMUSG00000072872 0.386764557826432 0.580146836739649 0.382296177582122 0.580146836739649 0.849676161042615 0.849676161042615
Gm4924 ENSMUSG00000073427 0.635566340219901 0.646962472199323 0.638409895415124 0.646962472199323 0.646962472199323 0.646962472199323
Zfp94 ENSMUSG00000074282 0.395556967321084 0.604948942256054 0.604948942256054 0.604948942256054 0.43866682563663 0.604948942256054
Etohi1 ENSMUSG00000074519 0.00555732722459425 0.0166719816737827 0.0941805625037277 0.141270843755592 0.610438439112846 0.610438439112846
5830428H23Rik ENSMUSG00000074733 0.613252782036663 0.613252782036663 0.128961433513013 0.364701914375926 0.24313460958395 0.364701914375926
Zfp934 ENSMUSG00000074865 0.602222434294486 0.602222434294486 0.545641118059147 0.602222434294486 0.395520999333589 0.602222434294486
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
AU041133 ENSMUSG00000078435 0.532559173816322 0.532559173816322 0.107365303535444 0.322095910606332 0.375840048285497 0.532559173816322
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773
Zfp566 ENSMUSG00000078768 0.311349031679773 0.770198117090135 0.770181200504567 0.770198117090135 0.770198117090135 0.770198117090135
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Zfp703 ENSMUSG00000085795 0.899499086347557 0.899499086347557 0.610502006548519 0.899499086347557 0.268105013405796 0.804315040217388
Zfp882 ENSMUSG00000089857 0.138355094383173 0.415065283149518 0.849731095697754 0.849731095697754 0.332711815049975 0.499067722574962
Gm15446 ENSMUSG00000090015 0.158543303459984 0.273187033932232 0.182124689288155 0.273187033932232 0.524868302216941 0.524868302216941
Gm5141 ENSMUSG00000091183 0.728251981722718 0.785346672713238 0.785346672713238 0.785346672713238 0.529811219353198 0.785346672713238
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
2610021A01Rik ENSMUSG00000091474 0.0496472342066872 0.148941702620062 0.1596840208813 0.23952603132195 0.716487655240011 0.716487655240011
Zfp963 ENSMUSG00000092260 0.149247241613784 0.447741724841352 0.984253468681904 0.984253468681904 0.943367928879089 0.984253468681904
Med20 ENSMUSG00000092558 0.937078933921258 0.937078933921258 0.82504823661484 0.937078933921258 0.566945182108028 0.937078933921258
Gm4767 ENSMUSG00000094076 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp955a ENSMUSG00000094441 0.591268108386733 0.591268108386733 0.0460158911431359 0.138047673429408 0.431674183344687 0.591268108386733
Gm3604 ENSMUSG00000094942 0.968518933881967 0.968518933881967 0.44098731046428 0.830429198731452 0.553619465820968 0.830429198731452
Zfp870 ENSMUSG00000095325 0.80968410981223 0.80968410981223 0.422411415597203 0.633617123395805 0.296455215798333 0.633617123395805
Zfp748 ENSMUSG00000095432 0.29287279987543 0.45309017495156 0.302060116634373 0.45309017495156 0.569620779197383 0.569620779197383
Zfp960 ENSMUSG00000096696 0.782323385382656 0.782323385382656 0.10386320132676 0.31158960398028 0.564075420300437 0.782323385382656
Gm10778 ENSMUSG00000096856 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp87 ENSMUSG00000097333 0.307373830560574 0.461060745840861 0.0495595649496402 0.148678694848921 0.868301084753766 0.868301084753766

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.127086859667951 0.190630289501926 0.0880298593793974 0.190630289501926 0.455295294594226 0.455295294594226
Hnrnpd ENSMUSG00000000568 0.855891963062675 0.930789246918887 0.803626350984924 0.930789246918887 0.930789246918887 0.930789246918887
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Smg5 ENSMUSG00000001415 0.415483851189053 0.623225776783579 0.233626583305425 0.623225776783579 0.791356325064641 0.791356325064641
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Sf3a1 ENSMUSG00000002129 0.840438875170834 0.840438875170834 0.728300208308162 0.840438875170834 0.429243825447866 0.840438875170834
Smg9 ENSMUSG00000002210 0.28560283616571 0.85680850849713 0.644117746873212 0.966176620309818 0.987404418508382 0.987404418508382
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Puf60 ENSMUSG00000002524 0.122126688897098 0.183190033345647 0.0473430856036172 0.142029256810851 0.53779597419782 0.53779597419782
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Nob1 ENSMUSG00000003848 0.773248898466916 0.821999622588008 0.821999622588008 0.821999622588008 0.561600850274487 0.821999622588008
Cwc15 ENSMUSG00000004096 0.572269538520786 0.865240266985103 0.684298391674831 0.865240266985103 0.865240266985103 0.865240266985103
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prcc ENSMUSG00000004895 0.635599661383936 0.635599661383936 0.0910004551454026 0.273001365436208 0.591238961662756 0.635599661383936
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Senp3 ENSMUSG00000005204 0.58577596310403 0.743172010585728 0.386779443093479 0.743172010585728 0.743172010585728 0.743172010585728
Wbscr22 ENSMUSG00000005378 0.479317845343454 0.814347307096454 0.542898204730969 0.814347307096454 0.987395917271809 0.987395917271809
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Bcas2 ENSMUSG00000005687 0.862076641749625 0.886958979907288 0.365312252212635 0.886958979907288 0.886958979907288 0.886958979907288
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Khsrp ENSMUSG00000007670 0.837321743303952 0.921404784610143 0.921404784610143 0.921404784610143 0.862068813004363 0.921404784610143
Hnrnpa0 ENSMUSG00000007836 0.230566309369634 0.345849464054451 0.0249571024305369 0.0748713072916106 0.761182380443518 0.761182380443518
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Prpf31 ENSMUSG00000008373 0.927669343869935 0.927669343869935 0.737204864427204 0.927669343869935 0.36741760703245 0.927669343869935
Tnpo1 ENSMUSG00000009470 0.494417786200833 0.788383945704149 0.788383945704149 0.788383945704149 0.687209982750423 0.788383945704149
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Sugp1 ENSMUSG00000011306 0.274817104073723 0.82445131222117 0.794481324664869 0.990549530945263 0.990549530945263 0.990549530945263
Rpl15 ENSMUSG00000012405 0.716465716009904 0.716465716009904 0.522265564650336 0.716465716009904 0.641299115175891 0.716465716009904
Hnrnpl ENSMUSG00000015165 0.290708711947854 0.624288396551694 0.514383808587368 0.624288396551694 0.624288396551694 0.624288396551694
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Prpf3 ENSMUSG00000015748 0.887020085974762 0.887020085974762 0.803632537244706 0.887020085974762 0.627217570846182 0.887020085974762
Ppil4 ENSMUSG00000015757 0.330691144462917 0.496036716694376 0.31713951747283 0.496036716694376 0.852775108802872 0.852775108802872
Skiv2l2 ENSMUSG00000016018 0.119136042931793 0.357408128795379 0.238396318461405 0.357594477692107 0.877613080915908 0.877613080915908
Nt5c3b ENSMUSG00000017176 0.840372799791322 0.840393572668707 0.840393572668707 0.840393572668707 0.716475716566378 0.840393572668707
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Exosc10 ENSMUSG00000017264 0.749152646721473 0.749152646721473 0.378106677050551 0.567160015575827 0.31140300100266 0.567160015575827
Rrp7a ENSMUSG00000018040 0.692852013372061 0.883803684161346 0.681326374472611 0.883803684161346 0.883803684161346 0.883803684161346
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Nol11 ENSMUSG00000018433 0.550976295604213 0.81586174563341 0.81586174563341 0.81586174563341 0.596748852222188 0.81586174563341
Cwc25 ENSMUSG00000018541 0.968514516979504 0.968514516979504 0.812796679924482 0.968514516979504 0.710545147168425 0.968514516979504
Pelp1 ENSMUSG00000018921 0.300183280419938 0.627230462903299 0.460086442729433 0.627230462903299 0.627230462903299 0.627230462903299
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Smg8 ENSMUSG00000020495 0.868342926148662 0.868342926148662 0.162106880036404 0.486320640109213 0.746181698371716 0.868342926148662
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Riok1 ENSMUSG00000021428 0.479497884306649 0.719246826459974 0.317055166607037 0.719246826459974 0.943354933777801 0.943354933777801
Ddx46 ENSMUSG00000021500 0.136232818526581 0.408698455579741 0.42249855869066 0.63374783803599 0.905713436224748 0.905713436224748
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Smn1 ENSMUSG00000021645 0.326871571824232 0.809722038047398 0.800560045965864 0.809722038047398 0.809722038047398 0.809722038047398
Cwc27 ENSMUSG00000021715 0.0500840677767623 0.0751261016651435 0.000466158734168928 0.00139847620250679 0.59617013105787 0.59617013105787
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Wbp4 ENSMUSG00000022023 0.57767409160757 0.940226722054822 0.81280258883619 0.940226722054822 0.940226722054822 0.940226722054822
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Bop1 ENSMUSG00000022557 0.411115516265274 0.517096526628002 0.276760058045995 0.517096526628002 0.517096526628002 0.517096526628002
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Eif4a2 ENSMUSG00000022884 0.776262606175218 0.794463575615136 0.509527671271441 0.794463575615136 0.794463575615136 0.794463575615136
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cdc5l ENSMUSG00000023932 0.908822319977401 0.908822319977401 0.218320367929368 0.654961103788104 0.55070490413027 0.826057356195404
Bysl ENSMUSG00000023988 0.422521195041888 0.633781792562832 0.00126187634452256 0.00378562903356768 0.815865380496656 0.815865380496656
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Rbm22 ENSMUSG00000024604 0.558919808180084 0.678487645353992 0.678487645353992 0.678487645353992 0.672727756407916 0.678487645353992
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Sf1 ENSMUSG00000024949 0.996851247529016 0.996851247529016 0.602234646766558 0.996851247529016 0.915140925930742 0.996851247529016
Smndc1 ENSMUSG00000025024 0.965367521438985 0.965367521438985 0.26634545215952 0.799036356478559 0.821988383582378 0.965367521438985
Pdcd11 ENSMUSG00000025047 0.716487352246628 0.716487352246628 0.408914776356 0.675779562605419 0.450519708403612 0.675779562605419
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Wdr75 ENSMUSG00000025995 0.328827310390672 0.493240965586008 0.283816811800618 0.493240965586008 0.865239864601655 0.865239864601655
Wdr12 ENSMUSG00000026019 0.322960087013568 0.949257574175575 0.632838382783717 0.949257574175575 0.981107724659299 0.981107724659299
Ppil3 ENSMUSG00000026035 0.548325476095461 0.838402715883537 0.971666463054836 0.971666463054836 0.558935143922358 0.838402715883537
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Ncl ENSMUSG00000026234 0.388918997733848 0.583378496600772 0.365397588191309 0.583378496600772 0.788352813942849 0.788352813942849
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Cwc22 ENSMUSG00000027014 0.812805789263119 1 0.782304377698204 1 1 1
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Nop56 ENSMUSG00000027405 0.51207682286063 0.616015484623619 0.613172662491066 0.616015484623619 0.616015484623619 0.616015484623619
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ctnnbl1 ENSMUSG00000027649 0.658377821420181 0.782320636449417 0.782320636449417 0.782320636449417 0.635670240395242 0.782320636449417
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Ddx20 ENSMUSG00000027905 0.859038138942191 0.962224450626547 0.529990757346025 0.962224450626547 0.962224450626547 0.962224450626547
Adar ENSMUSG00000027951 0.621552652137763 0.632730031988286 0.632730031988286 0.632730031988286 0.363301905244055 0.632730031988286
Rnpc3 ENSMUSG00000027981 0.496926771619955 0.745390157429933 0.251292362417855 0.745390157429933 0.927676463240204 0.927676463240204
Plrg1 ENSMUSG00000027998 0.68140120643685 0.68140120643685 0.486892343577072 0.68140120643685 0.477018689801654 0.68140120643685
Mettl14 ENSMUSG00000028114 0.661244082066661 0.943364652532181 0.746167983285611 0.943364652532181 0.943364652532181 0.943364652532181
Tgs1 ENSMUSG00000028233 0.202445619281456 0.607336857844367 0.681406823438836 0.722389056632982 0.722389056632982 0.722389056632982
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Tex10 ENSMUSG00000028345 0.698861183024974 0.809720516350387 0.58307474457931 0.809720516350387 0.809720516350387 0.809720516350387
Rps6 ENSMUSG00000028495 0.332453418387945 0.367177841714712 0.0428179702760643 0.128453910828193 0.367177841714712 0.367177841714712
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Ebna1bp2 ENSMUSG00000028729 0.773240105420786 0.773240105420786 0.627224228701954 0.773240105420786 0.599489823020396 0.773240105420786
Sf3a3 ENSMUSG00000028902 0.933947680963532 0.933947680963532 0.87455809977212 0.933947680963532 0.519685402329841 0.933947680963532
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Nol9 ENSMUSG00000028948 0.202412713451824 0.576932625557969 0.384621750371979 0.576932625557969 0.752139710308001 0.752139710308001
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Tfip11 ENSMUSG00000029345 0.443298801485242 0.652587822376045 0.205334332181454 0.616002996544363 0.652587822376045 0.652587822376045
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Dhx37 ENSMUSG00000029480 0.415666229212089 0.623499343818133 0.212496559484483 0.623499343818133 0.746163903919091 0.746163903919091
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Pan3 ENSMUSG00000029647 0.655456393746432 0.849722654511013 0.524801691324984 0.849722654511013 0.849722654511013 0.849722654511013
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Bms1 ENSMUSG00000030138 0.852810376510079 0.852810376510079 0.585806547581933 0.852810376510079 0.713480715892769 0.852810376510079
Ddx47 ENSMUSG00000030204 0.388849045338707 0.583273568008061 0.25457775638113 0.583273568008061 0.585698633896517 0.585698633896517
Wbp11 ENSMUSG00000030216 0.859032843384184 0.859032843384184 0.566928581651813 0.859032843384184 0.719432498480505 0.859032843384184
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Snrpa1 ENSMUSG00000030512 0.269803315688056 0.404704973532084 0.0872801468469727 0.261840440540918 0.585829879420865 0.585829879420865
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Smg1 ENSMUSG00000030655 0.472068853116066 0.80672069669531 0.537813797796873 0.80672069669531 0.825014254504631 0.825014254504631
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Gpkow ENSMUSG00000031148 0.128082895227264 0.279110114968284 0.186073409978856 0.279110114968284 0.548333435556311 0.548333435556311
Pqbp1 ENSMUSG00000031157 0.666965418978755 0.719418000318808 0.0858192421217162 0.257457726365149 0.719418000318808 0.719418000318808
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Mphosph6 ENSMUSG00000031843 0.522199300603304 0.783298950904956 0.268083439074963 0.783298950904956 0.840444590221339 0.840444590221339
Nip7 ENSMUSG00000031917 0.865240714073597 0.865240714073597 0.532645878282739 0.865240714073597 0.624428878860974 0.865240714073597
Ddx6 ENSMUSG00000032097 0.404397194234859 0.752177062517396 0.752177062517396 0.752177062517396 0.652647416539278 0.752177062517396
Anp32a ENSMUSG00000032249 0.740192056526801 0.818916972373276 0.818916972373276 0.818916972373276 0.73124464254036 0.818916972373276
U2surp ENSMUSG00000032407 0.382391809326972 0.704648147768288 0.469765431845525 0.704648147768288 0.737208398499227 0.737208398499227
Rbm5 ENSMUSG00000032580 0.779270754053549 0.779270754053549 0.467301384838239 0.779270754053549 0.684286646157794 0.779270754053549
Pwp2 ENSMUSG00000032834 0.199669971734496 0.299504957601743 0.0696231421464657 0.208869426439397 0.646960891212126 0.646960891212126
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Wdr3 ENSMUSG00000033285 0.522205583831546 0.783308375747319 0.899486392537053 0.899486392537053 0.315242060316648 0.783308375747319
Noc4l ENSMUSG00000033294 0.0721412837918802 0.10821192568782 0.0352958134982559 0.105887440494768 0.687153115247961 0.687153115247961
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Ttc37 ENSMUSG00000033991 0.209479265727045 0.314218898590567 0.161957506810136 0.314218898590567 0.602092125220025 0.602092125220025
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Zcchc11 ENSMUSG00000034610 0.871429201699317 0.927668208119842 0.448129353121277 0.927668208119842 0.927668208119842 0.927668208119842
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Gcfc2 ENSMUSG00000035125 0.350923631929971 0.655522796195744 0.467316130174812 0.655522796195744 0.655522796195744 0.655522796195744
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Utp6 ENSMUSG00000035575 0.0430055834547232 0.12901675036417 0.144882604793049 0.217323907189574 0.7641958689898 0.7641958689898
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Wdr18 ENSMUSG00000035754 0.124840073407786 0.187260110111679 0.00435858464434846 0.0130757539330454 0.320632160465156 0.320632160465156
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Nop14 ENSMUSG00000036693 0.602240204895973 0.90336030734396 0.221411091834019 0.664233275502057 0.962228117270159 0.962228117270159
Rbmxl1 ENSMUSG00000037070 0.216947576817546 0.535655779262514 0.357103852841676 0.535655779262514 0.652665364959371 0.652665364959371
Rbm17 ENSMUSG00000037197 0.949640762876706 0.949640762876706 0.684204858403164 0.949640762876706 0.641282419372059 0.949640762876706
Gemin5 ENSMUSG00000037275 0.35498753165118 0.53248129747677 0.0619870721452988 0.185961216435896 0.791428611405528 0.791428611405528
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Smg6 ENSMUSG00000038290 0.828114065290397 0.883890839950755 0.713539549054289 0.883890839950755 0.883890839950755 0.883890839950755
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Upf3a ENSMUSG00000038398 0.868307354029982 0.868307354029982 0.806682984557619 0.868307354029982 0.537758592553213 0.868307354029982
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Edc3 ENSMUSG00000038957 0.296508606448352 0.590017516235972 0.393345010823981 0.590017516235972 0.701792729756973 0.701792729756973
Sart1 ENSMUSG00000039148 0.255682116626992 0.383523174940487 0.150285264886121 0.383523174940487 0.846527772540081 0.846527772540081
Srrm2 ENSMUSG00000039218 0.599225711624519 0.818851114514297 0.176834243249748 0.530502729749244 0.818851114514297 0.818851114514297
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Hnrnpu ENSMUSG00000039630 0.545644981217212 0.871449753757413 0.755143033014401 0.871449753757413 0.871449753757413 0.871449753757413
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Skiv2l ENSMUSG00000040356 0.320818972045176 0.481228458067763 0.303842486320552 0.481228458067763 0.812719792582066 0.812719792582066
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Gemin8 ENSMUSG00000040621 0.256037057548284 0.768111172644851 0.588307079872917 0.882460619809375 0.899487888803449 0.899487888803449
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Tbl3 ENSMUSG00000040688 0.0916980582103184 0.137547087315478 0.00975864054692178 0.0292759216407653 0.149260377687781 0.149260377687781
Hnrnpul1 ENSMUSG00000040725 0.773129846978817 0.949635296196564 0.937086968663867 0.949635296196564 0.949635296196564 0.949635296196564
Snrnp25 ENSMUSG00000040767 0.144873289929696 0.381892931885658 0.254595287923772 0.381892931885658 0.530061457689675 0.530061457689675
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cirh1a ENSMUSG00000041438 0.338768556428345 0.764282629999178 0.946507266444644 0.946507266444644 0.509521753332785 0.764282629999178
Dcp1b ENSMUSG00000041477 0.737228299731999 0.955937196174637 0.556281929705088 0.955937196174637 0.955937196174637 0.955937196174637
Rrp9 ENSMUSG00000041506 0.188761652881877 0.566284958645632 0.504460592194509 0.756690888291764 0.937089702298458 0.937089702298458
Utp15 ENSMUSG00000041747 0.722343772711313 0.722343772711313 0.569577633307332 0.722343772711313 0.616004479594876 0.722343772711313
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Cd2bp2 ENSMUSG00000042502 0.782245545584187 0.782245545584187 0.512054317172143 0.768081475758215 0.494260435019555 0.768081475758215
Smg7 ENSMUSG00000042772 0.30382898679522 0.911486960385659 0.930810925390078 0.930810925390078 0.930788722436065 0.930810925390078
Upf2 ENSMUSG00000043241 0.344813571752927 0.862136435003613 0.862136435003613 0.862136435003613 0.849735622506626 0.862136435003613
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Lsm11 ENSMUSG00000044847 0.436363548388505 0.654545322582758 0.219769748508287 0.654545322582758 0.692921430693931 0.692921430693931
Hnrnph2 ENSMUSG00000045427 0.0887814689864825 0.266344406959447 0.209611303234731 0.314416954852097 0.965363137104306 0.965363137104306
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Patl1 ENSMUSG00000046139 0.393283354429965 0.633716138428704 0.422477425619136 0.633716138428704 0.971664088103294 0.971664088103294
Rpl27a ENSMUSG00000046364 0.486953491393843 0.915127538804999 0.74616335633815 0.915127538804999 0.915127538804999 0.915127538804999
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Gemin4 ENSMUSG00000049396 0.728280763310707 0.728280763310707 0.399829192861332 0.599743789291998 0.198256909157096 0.594770727471287
Heatr1 ENSMUSG00000050244 0.746181096159091 0.752175054763424 0.752175054763424 0.752175054763424 0.698862686730887 0.752175054763424
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Utp18 ENSMUSG00000054079 0.825030315297898 0.825030315297898 0.219866547684685 0.659599643054055 0.773197603599864 0.825030315297898
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Dnajc8 ENSMUSG00000054405 0.120258770227668 0.180388155341502 0.119289712862716 0.180388155341502 0.675561509952905 0.675561509952905
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295
Snupn ENSMUSG00000055334 0.448132247942238 0.752823647500484 0.50188243166699 0.752823647500484 0.9590809387123 0.9590809387123
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Usp39 ENSMUSG00000056305 0.868237627224644 0.868237627224644 0.501875065011385 0.868237627224644 0.60474327807067 0.868237627224644
Pcbp2 ENSMUSG00000056851 0.77922054163382 0.77922054163382 0.380272711965077 0.77922054163382 0.758120657806994 0.77922054163382
Txnl4a ENSMUSG00000057130 0.236357181189437 0.354535771784155 0.230151656915334 0.354535771784155 0.489307092916846 0.489307092916846
Las1l ENSMUSG00000057421 0.678483169094734 0.837381101779246 0.618863398982669 0.837381101779246 0.837381101779246 0.837381101779246
Ddx49 ENSMUSG00000057788 0.550974648231518 1 0.812794812756199 1 1 1
Upf1 ENSMUSG00000058301 0.454990649563274 0.682485974344911 0.244773325539504 0.682485974344911 0.949621956320562 0.949621956320562
Rpl5 ENSMUSG00000058558 0.883851475294508 0.883851475294508 0.346774973373787 0.883851475294508 0.791411246773245 0.883851475294508
Hnrnpa3 ENSMUSG00000059005 0.105636484960633 0.316909454881898 0.81888866547801 0.921391871133013 0.921391871133013 0.921391871133013
Rpl3 ENSMUSG00000060036 0.604814804072583 0.837312671662592 0.837312671662592 0.837312671662592 0.588539563068734 0.837312671662592
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Snrpa ENSMUSG00000061479 0.534605497823689 0.555609483286124 0.170606409808356 0.511819229425067 0.555609483286124 0.555609483286124
Krr1 ENSMUSG00000063334 0.678509854333567 0.927676527659297 0.303934740582271 0.911804221746813 0.927676527659297 0.927676527659297
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Snrnp70 ENSMUSG00000063511 0.524782402817906 0.912009745810262 0.912009745810262 0.912009745810262 0.855890115741388 0.912009745810262
Prpf38a ENSMUSG00000063800 0.921406595137766 0.990553841719651 0.380312342168521 0.990553841719651 0.990553841719651 0.990553841719651
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hnrnpr ENSMUSG00000066037 0.90888267515115 0.90888267515115 0.652664168484424 0.90888267515115 0.812796803032516 0.90888267515115
Prpf4 ENSMUSG00000066148 0.828134400170103 0.828134400170103 0.812805235354818 0.828134400170103 0.509420357929062 0.828134400170103
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Rpl31 ENSMUSG00000073702 0.852839186481883 0.852839186481883 0.773231680871232 0.852839186481883 0.624431821651762 0.852839186481883
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773
Rps13 ENSMUSG00000090862 0.29630077432146 0.40846885160083 0.0136541774831532 0.0409625324494596 0.40846885160083 0.40846885160083

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.855891963062675 0.930789246918887 0.803626350984924 0.930789246918887 0.930789246918887 0.930789246918887
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Sf3a1 ENSMUSG00000002129 0.840438875170834 0.840438875170834 0.728300208308162 0.840438875170834 0.429243825447866 0.840438875170834
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Puf60 ENSMUSG00000002524 0.122126688897098 0.183190033345647 0.0473430856036172 0.142029256810851 0.53779597419782 0.53779597419782
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Cwc15 ENSMUSG00000004096 0.572269538520786 0.865240266985103 0.684298391674831 0.865240266985103 0.865240266985103 0.865240266985103
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prcc ENSMUSG00000004895 0.635599661383936 0.635599661383936 0.0910004551454026 0.273001365436208 0.591238961662756 0.635599661383936
Bcas2 ENSMUSG00000005687 0.862076641749625 0.886958979907288 0.365312252212635 0.886958979907288 0.886958979907288 0.886958979907288
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Hnrnpa0 ENSMUSG00000007836 0.230566309369634 0.345849464054451 0.0249571024305369 0.0748713072916106 0.761182380443518 0.761182380443518
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Prpf31 ENSMUSG00000008373 0.927669343869935 0.927669343869935 0.737204864427204 0.927669343869935 0.36741760703245 0.927669343869935
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Sugp1 ENSMUSG00000011306 0.274817104073723 0.82445131222117 0.794481324664869 0.990549530945263 0.990549530945263 0.990549530945263
Hnrnpl ENSMUSG00000015165 0.290708711947854 0.624288396551694 0.514383808587368 0.624288396551694 0.624288396551694 0.624288396551694
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Prpf3 ENSMUSG00000015748 0.887020085974762 0.887020085974762 0.803632537244706 0.887020085974762 0.627217570846182 0.887020085974762
Ppil4 ENSMUSG00000015757 0.330691144462917 0.496036716694376 0.31713951747283 0.496036716694376 0.852775108802872 0.852775108802872
Skiv2l2 ENSMUSG00000016018 0.119136042931793 0.357408128795379 0.238396318461405 0.357594477692107 0.877613080915908 0.877613080915908
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Cwc25 ENSMUSG00000018541 0.968514516979504 0.968514516979504 0.812796679924482 0.968514516979504 0.710545147168425 0.968514516979504
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Ddx46 ENSMUSG00000021500 0.136232818526581 0.408698455579741 0.42249855869066 0.63374783803599 0.905713436224748 0.905713436224748
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Cwc27 ENSMUSG00000021715 0.0500840677767623 0.0751261016651435 0.000466158734168928 0.00139847620250679 0.59617013105787 0.59617013105787
Wbp4 ENSMUSG00000022023 0.57767409160757 0.940226722054822 0.81280258883619 0.940226722054822 0.940226722054822 0.940226722054822
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cdc5l ENSMUSG00000023932 0.908822319977401 0.908822319977401 0.218320367929368 0.654961103788104 0.55070490413027 0.826057356195404
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Rbm22 ENSMUSG00000024604 0.558919808180084 0.678487645353992 0.678487645353992 0.678487645353992 0.672727756407916 0.678487645353992
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Sf1 ENSMUSG00000024949 0.996851247529016 0.996851247529016 0.602234646766558 0.996851247529016 0.915140925930742 0.996851247529016
Smndc1 ENSMUSG00000025024 0.965367521438985 0.965367521438985 0.26634545215952 0.799036356478559 0.821988383582378 0.965367521438985
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Ppil3 ENSMUSG00000026035 0.548325476095461 0.838402715883537 0.971666463054836 0.971666463054836 0.558935143922358 0.838402715883537
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Cwc22 ENSMUSG00000027014 0.812805789263119 1 0.782304377698204 1 1 1
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ctnnbl1 ENSMUSG00000027649 0.658377821420181 0.782320636449417 0.782320636449417 0.782320636449417 0.635670240395242 0.782320636449417
Rnpc3 ENSMUSG00000027981 0.496926771619955 0.745390157429933 0.251292362417855 0.745390157429933 0.927676463240204 0.927676463240204
Plrg1 ENSMUSG00000027998 0.68140120643685 0.68140120643685 0.486892343577072 0.68140120643685 0.477018689801654 0.68140120643685
Mettl14 ENSMUSG00000028114 0.661244082066661 0.943364652532181 0.746167983285611 0.943364652532181 0.943364652532181 0.943364652532181
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Sf3a3 ENSMUSG00000028902 0.933947680963532 0.933947680963532 0.87455809977212 0.933947680963532 0.519685402329841 0.933947680963532
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Tfip11 ENSMUSG00000029345 0.443298801485242 0.652587822376045 0.205334332181454 0.616002996544363 0.652587822376045 0.652587822376045
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Wbp11 ENSMUSG00000030216 0.859032843384184 0.859032843384184 0.566928581651813 0.859032843384184 0.719432498480505 0.859032843384184
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Snrpa1 ENSMUSG00000030512 0.269803315688056 0.404704973532084 0.0872801468469727 0.261840440540918 0.585829879420865 0.585829879420865
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Gpkow ENSMUSG00000031148 0.128082895227264 0.279110114968284 0.186073409978856 0.279110114968284 0.548333435556311 0.548333435556311
Pqbp1 ENSMUSG00000031157 0.666965418978755 0.719418000318808 0.0858192421217162 0.257457726365149 0.719418000318808 0.719418000318808
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
U2surp ENSMUSG00000032407 0.382391809326972 0.704648147768288 0.469765431845525 0.704648147768288 0.737208398499227 0.737208398499227
Rbm5 ENSMUSG00000032580 0.779270754053549 0.779270754053549 0.467301384838239 0.779270754053549 0.684286646157794 0.779270754053549
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Gcfc2 ENSMUSG00000035125 0.350923631929971 0.655522796195744 0.467316130174812 0.655522796195744 0.655522796195744 0.655522796195744
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Rbmxl1 ENSMUSG00000037070 0.216947576817546 0.535655779262514 0.357103852841676 0.535655779262514 0.652665364959371 0.652665364959371
Rbm17 ENSMUSG00000037197 0.949640762876706 0.949640762876706 0.684204858403164 0.949640762876706 0.641282419372059 0.949640762876706
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Sart1 ENSMUSG00000039148 0.255682116626992 0.383523174940487 0.150285264886121 0.383523174940487 0.846527772540081 0.846527772540081
Srrm2 ENSMUSG00000039218 0.599225711624519 0.818851114514297 0.176834243249748 0.530502729749244 0.818851114514297 0.818851114514297
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Hnrnpu ENSMUSG00000039630 0.545644981217212 0.871449753757413 0.755143033014401 0.871449753757413 0.871449753757413 0.871449753757413
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Hnrnpul1 ENSMUSG00000040725 0.773129846978817 0.949635296196564 0.937086968663867 0.949635296196564 0.949635296196564 0.949635296196564
Snrnp25 ENSMUSG00000040767 0.144873289929696 0.381892931885658 0.254595287923772 0.381892931885658 0.530061457689675 0.530061457689675
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Cd2bp2 ENSMUSG00000042502 0.782245545584187 0.782245545584187 0.512054317172143 0.768081475758215 0.494260435019555 0.768081475758215
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Hnrnph2 ENSMUSG00000045427 0.0887814689864825 0.266344406959447 0.209611303234731 0.314416954852097 0.965363137104306 0.965363137104306
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Dnajc8 ENSMUSG00000054405 0.120258770227668 0.180388155341502 0.119289712862716 0.180388155341502 0.675561509952905 0.675561509952905
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Usp39 ENSMUSG00000056305 0.868237627224644 0.868237627224644 0.501875065011385 0.868237627224644 0.60474327807067 0.868237627224644
Pcbp2 ENSMUSG00000056851 0.77922054163382 0.77922054163382 0.380272711965077 0.77922054163382 0.758120657806994 0.77922054163382
Txnl4a ENSMUSG00000057130 0.236357181189437 0.354535771784155 0.230151656915334 0.354535771784155 0.489307092916846 0.489307092916846
Hnrnpa3 ENSMUSG00000059005 0.105636484960633 0.316909454881898 0.81888866547801 0.921391871133013 0.921391871133013 0.921391871133013
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Snrpa ENSMUSG00000061479 0.534605497823689 0.555609483286124 0.170606409808356 0.511819229425067 0.555609483286124 0.555609483286124
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Snrnp70 ENSMUSG00000063511 0.524782402817906 0.912009745810262 0.912009745810262 0.912009745810262 0.855890115741388 0.912009745810262
Prpf38a ENSMUSG00000063800 0.921406595137766 0.990553841719651 0.380312342168521 0.990553841719651 0.990553841719651 0.990553841719651
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hnrnpr ENSMUSG00000066037 0.90888267515115 0.90888267515115 0.652664168484424 0.90888267515115 0.812796803032516 0.90888267515115
Prpf4 ENSMUSG00000066148 0.828134400170103 0.828134400170103 0.812805235354818 0.828134400170103 0.509420357929062 0.828134400170103
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Rarg ENSMUSG00000001288 0.0949507440318001 0.2848522320954 0.577661162633673 0.86649174395051 0.937080448558437 0.937080448558437
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Taco1 ENSMUSG00000001983 0.086484862945857 0.259454588837571 0.815861281163154 0.815861281163154 0.528925419338586 0.793388129007879
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Supt6 ENSMUSG00000002052 0.918249683822428 0.921384615446289 0.509525588181232 0.921384615446289 0.921384615446289 0.921384615446289
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Med6 ENSMUSG00000002679 0.990552165598131 0.990552165598131 0.558936418167482 0.990552165598131 0.672681426758166 0.990552165598131
Med25 ENSMUSG00000002968 0.971653838289879 0.971653838289879 0.908873487166612 0.971653838289879 0.4670905839486 0.971653838289879
Cdk12 ENSMUSG00000003119 0.755162148087285 0.93394600324458 0.67272885843545 0.93394600324458 0.93394600324458 0.93394600324458
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Zfp81 ENSMUSG00000003929 0.921398276173297 0.921398276173297 0.450420982394875 0.921398276173297 0.865197012496934 0.921398276173297
Zfp324 ENSMUSG00000004500 0.927677083266821 0.927677083266821 0.734248202546478 0.927677083266821 0.716448379206918 0.927677083266821
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Trim28 ENSMUSG00000005566 0.0696552212572158 0.208965663771647 0.149279783577451 0.223919675366176 0.56151364795391 0.56151364795391
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ctcf ENSMUSG00000005698 0.481928119997173 0.880785231141268 0.880785231141268 0.880785231141268 0.868318228371637 0.880785231141268
Nr2c2 ENSMUSG00000005893 0.764183193354547 0.877616202117077 0.74011847951785 0.877616202117077 0.877616202117077 0.877616202117077
Ttc5 ENSMUSG00000006288 0.289245761101568 0.797531873832735 0.797531873832735 0.797531873832735 0.591266864698899 0.797531873832735
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Rbm14 ENSMUSG00000006456 0.208168357957752 0.569522474062835 0.504457351146993 0.569522474062835 0.569522474062835 0.569522474062835
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Phax ENSMUSG00000008301 0.593994621681469 0.890991932522203 0.299988765429107 0.890991932522203 0.908834658280149 0.908834658280149
Pou2f2 ENSMUSG00000008496 0.78440929149125 0.799568301739656 0.713183887624394 0.799568301739656 0.799568301739656 0.799568301739656
Hipk1 ENSMUSG00000008730 0.0940924963949365 0.28227748918481 0.713539120862588 0.713539120862588 0.684230035763789 0.713539120862588
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Zfp790 ENSMUSG00000011427 0.08725095874565 0.26175287623695 0.431745151093074 0.53262732242229 0.53262732242229 0.53262732242229
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Med15 ENSMUSG00000012114 0.821919378323644 0.893214949965843 0.710574761934654 0.893214949965843 0.893214949965843 0.893214949965843
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Surf1 ENSMUSG00000015790 0.440974576923634 0.661461865385452 0.666963880398388 0.666963880398388 0.422383519581425 0.661461865385452
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Med1 ENSMUSG00000018160 0.176912994511997 0.530738983535992 0.937088643933494 0.937088643933494 0.690096905754397 0.937088643933494
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Zkscan6 ENSMUSG00000018347 0.291057114673061 0.687202073468259 0.678505412905333 0.687202073468259 0.687202073468259 0.687202073468259
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Yeats4 ENSMUSG00000020171 0.658173758986959 0.933918552920911 0.238351538159865 0.715054614479596 0.933918552920911 0.933918552920911
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Med7 ENSMUSG00000020397 0.728213913004377 0.858987230162626 0.203769079948581 0.611307239845742 0.858987230162626 0.858987230162626
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Ppm1d ENSMUSG00000020525 0.624435190288112 0.794447909549847 0.794447909549847 0.794447909549847 0.585774454653853 0.794447909549847
Cox11 ENSMUSG00000020544 0.0434338691683981 0.0651508037525971 1.83822333159272e-06 5.51466999477816e-06 0.324900544328719 0.324900544328719
Rffl ENSMUSG00000020696 0.499406497178666 0.569551782735742 0.309533365572562 0.569551782735742 0.569551782735742 0.569551782735742
Med31 ENSMUSG00000020801 0.613191476590519 0.871411388586427 0.871411388586427 0.871411388586427 0.438725432334298 0.871411388586427
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Ppp1r13b ENSMUSG00000021285 0.707638838245221 0.785353922376112 0.785353922376112 0.785353922376112 0.779270489867307 0.785353922376112
A530054K11Rik ENSMUSG00000021510 0.079401470788274 0.121062123721737 0.0807080824811581 0.121062123721737 0.725217096412423 0.725217096412423
Med10 ENSMUSG00000021598 0.915124101313431 0.915124101313431 0.912007984588996 0.915124101313431 0.537724386371694 0.915124101313431
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ints9 ENSMUSG00000021975 0.883848910566009 0.883848910566009 0.215446663437689 0.646339990313066 0.669771745593722 0.883848910566009
Med4 ENSMUSG00000022109 0.594007900130456 0.891011850195685 0.208123102342938 0.624369307028813 0.965367834542043 0.965367834542043
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Zfp263 ENSMUSG00000022529 0.855866014430946 1 0.588496132615472 1 1 1
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Taf8 ENSMUSG00000023980 0.828124441516432 0.828124441516432 0.271482342300993 0.748921555648755 0.49928103709917 0.748921555648755
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Mllt1 ENSMUSG00000024212 0.974811565183814 0.974811565183814 0.543035961218538 0.974811565183814 0.837368583319366 0.974811565183814
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Epc1 ENSMUSG00000024240 0.16573552702746 0.497206581082381 0.393337278290945 0.590005917436418 0.632780075332655 0.632780075332655
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Zfp871 ENSMUSG00000024298 0.0398045680509124 0.119413704152737 0.0949677760423197 0.14245166406348 0.770224083518563 0.770224083518563
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Iws1 ENSMUSG00000024384 0.613303748580275 0.613303748580275 0.469731250453748 0.613303748580275 0.59672817939277 0.613303748580275
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Pcgf6 ENSMUSG00000025050 0.758178056805396 0.946510665533973 0.716486625058548 0.946510665533973 0.946510665533973 0.946510665533973
Ints4 ENSMUSG00000025133 0.63555889649176 0.63555889649176 0.397770259228666 0.596655388842999 0.127894607161556 0.383683821484669
Ldb1 ENSMUSG00000025223 0.410968262589304 0.862094308754716 0.862094308754716 0.862094308754716 0.577562753134684 0.862094308754716
Tbl1x ENSMUSG00000025246 0.949633171970116 0.990551854325694 0.782226920895053 0.990551854325694 0.990551854325694 0.990551854325694
Banp ENSMUSG00000025316 0.352973634799885 0.352973634799885 0.0550155669365745 0.165046700809724 0.313355013846564 0.352973634799885
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Nabp2 ENSMUSG00000025374 0.880731820019853 0.880731820019853 0.731275523020539 0.880731820019853 0.467153715493259 0.880731820019853
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Zfp202 ENSMUSG00000025602 0.232141296260803 0.693007696821341 0.693007696821341 0.693007696821341 0.572234447202385 0.693007696821341
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Zfp282 ENSMUSG00000025821 0.86520171122549 0.974808871158847 0.809701439928137 0.974808871158847 0.974808871158847 0.974808871158847
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Gls ENSMUSG00000026103 0.862052724029941 0.993702533374486 0.981097390127074 0.993702533374486 0.993702533374486 0.993702533374486
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Med27 ENSMUSG00000026799 0.188742580635213 0.283113870952819 0.130086868464712 0.283113870952819 0.380314155487782 0.380314155487782
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Notch1 ENSMUSG00000026923 0.322985784663396 0.669767231045251 0.669767231045251 0.669767231045251 0.489406609204599 0.669767231045251
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Tbl1xr1 ENSMUSG00000027630 0.486940143036373 0.730410214554559 0.380216907855341 0.730410214554559 0.971661244333188 0.971661244333188
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Rprd1b ENSMUSG00000027651 0.987403179376432 0.987403179376432 0.0127720652161165 0.0383161956483495 0.773218081372242 0.987403179376432
Skil ENSMUSG00000027660 0.0918417107601723 0.275525132280517 0.577695864050358 0.57769637430179 0.57769637430179 0.57769637430179
Ints3 ENSMUSG00000027933 0.812771540280415 0.92451428819997 0.116488043451683 0.34946413035505 0.92451428819997 0.92451428819997
Rprd2 ENSMUSG00000028106 0.499429620793092 0.955939609127718 0.908882118075782 0.955939609127718 0.955939609127718 0.955939609127718
Ccnc ENSMUSG00000028252 0.173136755541683 0.519410266625048 0.474582473879636 0.711873710819454 0.797518469681053 0.797518469681053
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Cpsf3l ENSMUSG00000029034 0.23996748249015 0.359951223735224 0.0865341636468342 0.259602490940503 0.406629341484474 0.406629341484474
Ssu72 ENSMUSG00000029038 0.136242829605009 0.204364244407513 0.0504278103517965 0.151283431055389 0.743144881051361 0.743144881051361
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Nrbp1 ENSMUSG00000029148 0.921403988638114 1 1 1 0.269837366248565 0.809512098745694
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Zfp12 ENSMUSG00000029587 0.422465897532989 0.912008816289995 0.740157948518281 0.912008816289995 0.912008816289995 0.912008816289995
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Cdk8 ENSMUSG00000029635 0.846634306273708 0.846634306273708 0.746156018411803 0.846634306273708 0.652647960471599 0.846634306273708
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Zfp606 ENSMUSG00000030386 0.687193336158729 0.81892925311892 0.313342433084137 0.81892925311892 0.81892925311892 0.81892925311892
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Zfp626 ENSMUSG00000030604 0.746171241161978 0.955937633582514 0.955937633582514 0.955937633582514 0.359155367155075 0.955937633582514
Tead2 ENSMUSG00000030796 0.902596998516483 0.921382103057572 0.550973178937966 0.921382103057572 0.921382103057572 0.921382103057572
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
G6pdx ENSMUSG00000031400 0.635393278727122 0.924487728862621 0.924487728862621 0.924487728862621 0.564262605828105 0.924487728862621
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Zfp90 ENSMUSG00000031907 0.883903287645641 0.883903287645641 0.704719387396106 0.883903287645641 0.543083039876083 0.883903287645641
Maml2 ENSMUSG00000031925 0.877637040192188 0.877637040192188 0.843497733680374 0.877637040192188 0.344585874854108 0.877637040192188
Med17 ENSMUSG00000031935 0.773233922582795 0.773233922582795 0.75215585817309 0.773233922582795 0.66981399974883 0.773233922582795
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Tcf12 ENSMUSG00000032228 0.18608468481739 0.420199050336649 0.322980092384098 0.420199050336649 0.420199050336649 0.420199050336649
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Rpap2 ENSMUSG00000033773 0.955928538716565 0.955928538716565 0.469746652759616 0.955928538716565 0.728234247481334 0.955928538716565
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Mga ENSMUSG00000033943 0.247957790892636 0.603307914405705 0.40220527627047 0.603307914405705 0.632801060084072 0.632801060084072
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Zfp944 ENSMUSG00000033972 0.209644304089903 0.566914450263349 0.411112217202674 0.566914450263349 0.566914450263349 0.566914450263349
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Zfp418 ENSMUSG00000034538 0.14268551345265 0.214028270178975 0.142652524867088 0.214028270178975 0.627237966620823 0.627237966620823
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Zfp661 ENSMUSG00000034800 0.477089366826772 0.575003228483636 0.292885080548305 0.575003228483636 0.575003228483636 0.575003228483636
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Ints6 ENSMUSG00000035161 0.148221007726829 0.444663023180488 0.602217565222341 0.773230202783295 0.773230202783295 0.773230202783295
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Cox18 ENSMUSG00000035505 0.388966256857858 0.583449385286787 0.0631197324422958 0.189359197326887 0.770219768862008 0.770219768862008
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Zfp157 ENSMUSG00000036898 0.737229317287235 0.874542761003085 0.22739896474232 0.68219689422696 0.874542761003085 0.874542761003085
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Med30 ENSMUSG00000038622 0.974812698215822 0.974812698215822 0.527451989710235 0.974812698215822 0.949651629146872 0.974812698215822
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Rbpj ENSMUSG00000039191 0.855923261172793 0.855923261172793 0.54306369608504 0.846381237030571 0.564254158020381 0.846381237030571
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Rxrb ENSMUSG00000039656 0.155039132458621 0.232558698687931 0.0843535974343253 0.232558698687931 0.550982840393409 0.550982840393409
Cited2 ENSMUSG00000039910 0.296426512311656 0.296426512311656 0.236651113528526 0.296426512311656 0.261261147442375 0.296426512311656
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Asun ENSMUSG00000040250 0.572283795940274 0.73127494591286 0.309570181456686 0.73127494591286 0.73127494591286 0.73127494591286
Zfp770 ENSMUSG00000040321 0.0421790568296861 0.126537170489058 0.921360891350043 0.921360891350043 0.815769388332954 0.921360891350043
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Ints8 ENSMUSG00000040738 0.191439387267038 0.574318161801113 0.949646823023688 0.990553161463228 0.990553161463228 0.990553161463228
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cdk13 ENSMUSG00000041297 0.350848580104832 0.89949118258729 0.788318112038651 0.89949118258729 0.89949118258729 0.89949118258729
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Zfp386 ENSMUSG00000042063 0.719407853271497 0.719407853271497 0.0173090693496571 0.0519272080489714 0.649794999527396 0.719407853271497
Kdm5b ENSMUSG00000042207 0.797529374580581 0.905741884779121 0.43164088085525 0.905741884779121 0.905741884779121 0.905741884779121
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Zfp784 ENSMUSG00000043290 0.102220206720847 0.306660620162542 0.509524073190022 0.764286109785034 0.883887904440387 0.883887904440387
Lsm11 ENSMUSG00000044847 0.436363548388505 0.654545322582758 0.219769748508287 0.654545322582758 0.692921430693931 0.692921430693931
Med26 ENSMUSG00000045248 0.852810083936291 0.871444332045489 0.445628277225206 0.871444332045489 0.871444332045489 0.871444332045489
Zfp688 ENSMUSG00000045251 0.0510429928638419 0.153128978591526 0.472043217252454 0.708064825878682 0.86517801866064 0.86517801866064
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Zfp740 ENSMUSG00000046897 0.215460677507988 0.646382032523965 0.558932463577806 0.834310029896056 0.834310029896056 0.834310029896056
Zfp445 ENSMUSG00000047036 0.382279221650018 0.573418832475027 0.182056555164653 0.546169665493958 0.834248971157118 0.834248971157118
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Zfp738 ENSMUSG00000048280 0.348832321796375 0.511999101472343 0.0786801495968421 0.236040448790526 0.511999101472343 0.511999101472343
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Zfp689 ENSMUSG00000048921 0.746161823092674 0.746161823092674 0.646960744142472 0.746161823092674 0.519698243563037 0.746161823092674
Prmt6 ENSMUSG00000049300 0.965374627946491 0.981108445923553 0.616073215983192 0.981108445923553 0.981108445923553 0.981108445923553
Zfp668 ENSMUSG00000049728 0.728318017081463 0.977954253101518 0.977954253101518 0.977954253101518 0.548222725753309 0.977954253101518
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Zfp61 ENSMUSG00000050605 0.728255393999416 0.80972891649625 0.296433823886353 0.80972891649625 0.80972891649625 0.80972891649625
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Zfp169 ENSMUSG00000050954 0.225956461911946 0.338934692867919 0.151599034348063 0.338934692867919 0.9653745468202 0.9653745468202
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Zfp961 ENSMUSG00000052446 0.313345469879295 0.51343843204474 0.342292288029827 0.51343843204474 0.537618763610479 0.537618763610479
Zfp212 ENSMUSG00000052763 0.0933273760001477 0.279982128000443 0.276778316078644 0.415167474117966 0.646917019555695 0.646917019555695
Yap1 ENSMUSG00000053110 0.180814967855615 0.271222451783422 0.0226891810822577 0.0680675432467731 0.632849896559277 0.632849896559277
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Zfp952 ENSMUSG00000053390 0.984257221868525 0.984257221868525 0.448158705547278 0.984257221868525 0.788397649478662 0.984257221868525
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Zfp867 ENSMUSG00000054519 0.00135825115299108 0.00407475345897325 0.434055483426102 0.434055483426102 0.141618529549119 0.212427794323679
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Zfp78 ENSMUSG00000055150 0.26627947686516 0.472921574890155 0.31528104992677 0.472921574890155 0.669832326835454 0.669832326835454
Zfp101 ENSMUSG00000055240 0.734262482213761 0.734262482213761 0.594012848288838 0.734262482213761 0.556278619594594 0.734262482213761
Zfp457 ENSMUSG00000055341 0.930746361961035 0.930746361961035 0.469074828413572 0.930746361961035 0.680944397078772 0.930746361961035
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Zfp459 ENSMUSG00000055560 0.890135106257556 0.911994958053049 0.874544220095528 0.911994958053049 0.911994958053049 0.911994958053049
Zkscan5 ENSMUSG00000055991 0.767196870167699 0.974810879105003 0.974810879105003 0.974810879105003 0.257929357432216 0.773788072296648
Zfp709 ENSMUSG00000056019 0.797521765668082 0.797521765668082 0.443426304833404 0.797521765668082 0.791439214671057 0.797521765668082
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Zfp658 ENSMUSG00000056592 0.228914595980664 0.529448402085402 0.352965601390268 0.529448402085402 0.740145018102158 0.740145018102158
Zfp180 ENSMUSG00000057101 0.635672883009121 0.716491563767633 0.50699756826521 0.716491563767633 0.716491563767633 0.716491563767633
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Zfp759 ENSMUSG00000057396 0.170558669666104 0.255838004499155 0.0613950170147065 0.184185051044119 0.716464382522481 0.716464382522481
Zfp317 ENSMUSG00000057551 0.955937432081627 0.955937432081627 0.350911493675258 0.919893453908227 0.613262302605485 0.919893453908227
Zfp746 ENSMUSG00000057691 0.716416334129172 0.91511973774182 0.690105046205586 0.91511973774182 0.91511973774182 0.91511973774182
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Zfp420 ENSMUSG00000058402 0.155023950321555 0.465071850964665 0.56424187734588 0.56424187734588 0.371750809395157 0.557626214092735
Max ENSMUSG00000059436 0.722392653421377 0.930812666801164 0.855938138929478 0.930812666801164 0.930812666801164 0.930812666801164
Zfp426 ENSMUSG00000059475 0.219940486145568 0.545696630321519 0.545696630321519 0.545696630321519 0.524863157898077 0.545696630321519
Zfp874b ENSMUSG00000059839 0.0310173143234376 0.0930519429703127 0.42943013546867 0.644145203203005 0.794479238099772 0.794479238099772
Zfp74 ENSMUSG00000059975 0.74312652221704 0.846609686576337 0.846609686576337 0.846609686576337 0.610487324547613 0.846609686576337
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Zfp937 ENSMUSG00000060336 0.50693038776156 0.52223685668885 0.371587959673858 0.52223685668885 0.52223685668885 0.52223685668885
Maml3 ENSMUSG00000061143 0.734134168310536 0.828152725615866 0.828152725615866 0.828152725615866 0.752082162914131 0.828152725615866
Zfp873 ENSMUSG00000061371 0.725355719425837 0.902625754780667 0.902625754780667 0.902625754780667 0.296514941101917 0.88954482330575
Zfp229 ENSMUSG00000061544 0.675617394576195 0.788380161701511 0.788380161701511 0.788380161701511 0.153832893418283 0.46149868025485
Zfp954 ENSMUSG00000062116 0.658369028217264 0.959082992771107 0.959081970344945 0.959082992771107 0.959082992771107 0.959082992771107
Zfp706 ENSMUSG00000062397 0.190066273777015 0.285099410665523 0.018087075658525 0.0542612269755749 0.837366899643581 0.837366899643581
Zfp398 ENSMUSG00000062519 0.564185686622195 0.877651726266627 0.849742320769921 0.877651726266627 0.877651726266627 0.877651726266627
Zfp28 ENSMUSG00000062861 0.486832734119497 0.803632902387604 0.803632902387604 0.803632902387604 0.624360129581231 0.803632902387604
Zfp780b ENSMUSG00000063047 0.39107661533431 0.467333115705241 0.467333115705241 0.467333115705241 0.34277150669525 0.467333115705241
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Zfp35 ENSMUSG00000063281 0.115441460058477 0.346324380175432 0.499295440472368 0.748943160708552 0.837307669061056 0.837307669061056
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Zkscan8 ENSMUSG00000063894 0.755157435922603 0.755157435922603 0.280297057034039 0.63035178324964 0.420234522166427 0.63035178324964
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Med14 ENSMUSG00000064127 0.159665944223733 0.4789978326712 0.896381429694953 0.896381429694953 0.740156213379708 0.896381429694953
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Zfp932 ENSMUSG00000066613 0.959072162115386 0.959072162115386 0.519630290172417 0.959072162115386 0.752175376007337 0.959072162115386
Zfp617 ENSMUSG00000066880 0.268096534148183 0.402144801222275 0.108317010074898 0.324951030224694 0.583011859976807 0.583011859976807
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Zfp760 ENSMUSG00000067928 0.48687582265191 0.548295288947333 0.522226293473166 0.548295288947333 0.548295288947333 0.548295288947333
Zfp948 ENSMUSG00000067931 0.0285453743051351 0.0856361229154051 0.195421754963501 0.293132632445251 0.937089239708422 0.937089239708422
Zfp160 ENSMUSG00000067942 0.924541399094157 0.924541399094157 0.249662670833093 0.748988012499278 0.610522750033069 0.915784125049603
Zfp442 ENSMUSG00000068130 0.334710899073492 0.502066348610238 0.178194264925847 0.502066348610238 0.537804113289125 0.537804113289125
Zfp120 ENSMUSG00000068134 0.828151554474058 0.828151554474058 0.445754607281558 0.828151554474058 0.825056118712257 0.828151554474058
Zfp467 ENSMUSG00000068551 0.672505367288898 0.701629588633727 0.701629588633727 0.701629588633727 0.106981150107606 0.320943450322817
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Gm5595 ENSMUSG00000069727 0.150466132955774 0.225699199433661 0.0696380933388098 0.208914280016429 0.737238389965789 0.737238389965789
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Zscan25 ENSMUSG00000070420 0.162071713401021 0.486215140203062 0.737235846318888 0.737235846318888 0.572289335338048 0.737235846318888
1700049G17Rik ENSMUSG00000070709 0.684297290588225 0.74319910385997 0.328836522252172 0.74319910385997 0.74319910385997 0.74319910385997
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Zfp213 ENSMUSG00000071256 0.448148041703337 0.672709536904298 0.672709536904298 0.672709536904298 0.5589248616806 0.672709536904298
Zfp942 ENSMUSG00000071267 0.0413590765633997 0.124077229690199 0.106407235061891 0.159610852592837 0.643989625953818 0.643989625953818
Zfp71-rs1 ENSMUSG00000071281 0.320955744765794 0.43629926817455 0.252950895013197 0.43629926817455 0.43629926817455 0.43629926817455
Ints5 ENSMUSG00000071652 0.34473034700903 0.517095520513545 0.115495177311501 0.346485531934502 0.782297835248887 0.782297835248887
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Rybp ENSMUSG00000072872 0.386764557826432 0.580146836739649 0.382296177582122 0.580146836739649 0.849676161042615 0.849676161042615
Gm4924 ENSMUSG00000073427 0.635566340219901 0.646962472199323 0.638409895415124 0.646962472199323 0.646962472199323 0.646962472199323
Zfp94 ENSMUSG00000074282 0.395556967321084 0.604948942256054 0.604948942256054 0.604948942256054 0.43866682563663 0.604948942256054
Etohi1 ENSMUSG00000074519 0.00555732722459425 0.0166719816737827 0.0941805625037277 0.141270843755592 0.610438439112846 0.610438439112846
5830428H23Rik ENSMUSG00000074733 0.613252782036663 0.613252782036663 0.128961433513013 0.364701914375926 0.24313460958395 0.364701914375926
Zfp934 ENSMUSG00000074865 0.602222434294486 0.602222434294486 0.545641118059147 0.602222434294486 0.395520999333589 0.602222434294486
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
AU041133 ENSMUSG00000078435 0.532559173816322 0.532559173816322 0.107365303535444 0.322095910606332 0.375840048285497 0.532559173816322
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773
Zfp566 ENSMUSG00000078768 0.311349031679773 0.770198117090135 0.770181200504567 0.770198117090135 0.770198117090135 0.770198117090135
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Zfp703 ENSMUSG00000085795 0.899499086347557 0.899499086347557 0.610502006548519 0.899499086347557 0.268105013405796 0.804315040217388
Zfp882 ENSMUSG00000089857 0.138355094383173 0.415065283149518 0.849731095697754 0.849731095697754 0.332711815049975 0.499067722574962
Gm15446 ENSMUSG00000090015 0.158543303459984 0.273187033932232 0.182124689288155 0.273187033932232 0.524868302216941 0.524868302216941
Gm5141 ENSMUSG00000091183 0.728251981722718 0.785346672713238 0.785346672713238 0.785346672713238 0.529811219353198 0.785346672713238
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
2610021A01Rik ENSMUSG00000091474 0.0496472342066872 0.148941702620062 0.1596840208813 0.23952603132195 0.716487655240011 0.716487655240011
Zfp963 ENSMUSG00000092260 0.149247241613784 0.447741724841352 0.984253468681904 0.984253468681904 0.943367928879089 0.984253468681904
Med20 ENSMUSG00000092558 0.937078933921258 0.937078933921258 0.82504823661484 0.937078933921258 0.566945182108028 0.937078933921258
Gm4767 ENSMUSG00000094076 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp955a ENSMUSG00000094441 0.591268108386733 0.591268108386733 0.0460158911431359 0.138047673429408 0.431674183344687 0.591268108386733
Gm3604 ENSMUSG00000094942 0.968518933881967 0.968518933881967 0.44098731046428 0.830429198731452 0.553619465820968 0.830429198731452
Zfp870 ENSMUSG00000095325 0.80968410981223 0.80968410981223 0.422411415597203 0.633617123395805 0.296455215798333 0.633617123395805
Zfp748 ENSMUSG00000095432 0.29287279987543 0.45309017495156 0.302060116634373 0.45309017495156 0.569620779197383 0.569620779197383
Zfp960 ENSMUSG00000096696 0.782323385382656 0.782323385382656 0.10386320132676 0.31158960398028 0.564075420300437 0.782323385382656
Gm10778 ENSMUSG00000096856 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp87 ENSMUSG00000097333 0.307373830560574 0.461060745840861 0.0495595649496402 0.148678694848921 0.868301084753766 0.868301084753766

mRNA Splicing - Major Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.855891963062675 0.930789246918887 0.803626350984924 0.930789246918887 0.930789246918887 0.930789246918887
Sf3a1 ENSMUSG00000002129 0.840438875170834 0.840438875170834 0.728300208308162 0.840438875170834 0.429243825447866 0.840438875170834
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Puf60 ENSMUSG00000002524 0.122126688897098 0.183190033345647 0.0473430856036172 0.142029256810851 0.53779597419782 0.53779597419782
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Cwc15 ENSMUSG00000004096 0.572269538520786 0.865240266985103 0.684298391674831 0.865240266985103 0.865240266985103 0.865240266985103
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prcc ENSMUSG00000004895 0.635599661383936 0.635599661383936 0.0910004551454026 0.273001365436208 0.591238961662756 0.635599661383936
Bcas2 ENSMUSG00000005687 0.862076641749625 0.886958979907288 0.365312252212635 0.886958979907288 0.886958979907288 0.886958979907288
Hnrnpa0 ENSMUSG00000007836 0.230566309369634 0.345849464054451 0.0249571024305369 0.0748713072916106 0.761182380443518 0.761182380443518
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Prpf31 ENSMUSG00000008373 0.927669343869935 0.927669343869935 0.737204864427204 0.927669343869935 0.36741760703245 0.927669343869935
Sugp1 ENSMUSG00000011306 0.274817104073723 0.82445131222117 0.794481324664869 0.990549530945263 0.990549530945263 0.990549530945263
Hnrnpl ENSMUSG00000015165 0.290708711947854 0.624288396551694 0.514383808587368 0.624288396551694 0.624288396551694 0.624288396551694
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Prpf3 ENSMUSG00000015748 0.887020085974762 0.887020085974762 0.803632537244706 0.887020085974762 0.627217570846182 0.887020085974762
Ppil4 ENSMUSG00000015757 0.330691144462917 0.496036716694376 0.31713951747283 0.496036716694376 0.852775108802872 0.852775108802872
Skiv2l2 ENSMUSG00000016018 0.119136042931793 0.357408128795379 0.238396318461405 0.357594477692107 0.877613080915908 0.877613080915908
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Cwc25 ENSMUSG00000018541 0.968514516979504 0.968514516979504 0.812796679924482 0.968514516979504 0.710545147168425 0.968514516979504
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Ddx46 ENSMUSG00000021500 0.136232818526581 0.408698455579741 0.42249855869066 0.63374783803599 0.905713436224748 0.905713436224748
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Cwc27 ENSMUSG00000021715 0.0500840677767623 0.0751261016651435 0.000466158734168928 0.00139847620250679 0.59617013105787 0.59617013105787
Wbp4 ENSMUSG00000022023 0.57767409160757 0.940226722054822 0.81280258883619 0.940226722054822 0.940226722054822 0.940226722054822
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cdc5l ENSMUSG00000023932 0.908822319977401 0.908822319977401 0.218320367929368 0.654961103788104 0.55070490413027 0.826057356195404
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Rbm22 ENSMUSG00000024604 0.558919808180084 0.678487645353992 0.678487645353992 0.678487645353992 0.672727756407916 0.678487645353992
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Sf1 ENSMUSG00000024949 0.996851247529016 0.996851247529016 0.602234646766558 0.996851247529016 0.915140925930742 0.996851247529016
Smndc1 ENSMUSG00000025024 0.965367521438985 0.965367521438985 0.26634545215952 0.799036356478559 0.821988383582378 0.965367521438985
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Ppil3 ENSMUSG00000026035 0.548325476095461 0.838402715883537 0.971666463054836 0.971666463054836 0.558935143922358 0.838402715883537
Cwc22 ENSMUSG00000027014 0.812805789263119 1 0.782304377698204 1 1 1
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Ctnnbl1 ENSMUSG00000027649 0.658377821420181 0.782320636449417 0.782320636449417 0.782320636449417 0.635670240395242 0.782320636449417
Plrg1 ENSMUSG00000027998 0.68140120643685 0.68140120643685 0.486892343577072 0.68140120643685 0.477018689801654 0.68140120643685
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Sf3a3 ENSMUSG00000028902 0.933947680963532 0.933947680963532 0.87455809977212 0.933947680963532 0.519685402329841 0.933947680963532
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Tfip11 ENSMUSG00000029345 0.443298801485242 0.652587822376045 0.205334332181454 0.616002996544363 0.652587822376045 0.652587822376045
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Wbp11 ENSMUSG00000030216 0.859032843384184 0.859032843384184 0.566928581651813 0.859032843384184 0.719432498480505 0.859032843384184
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Snrpa1 ENSMUSG00000030512 0.269803315688056 0.404704973532084 0.0872801468469727 0.261840440540918 0.585829879420865 0.585829879420865
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Gpkow ENSMUSG00000031148 0.128082895227264 0.279110114968284 0.186073409978856 0.279110114968284 0.548333435556311 0.548333435556311
Pqbp1 ENSMUSG00000031157 0.666965418978755 0.719418000318808 0.0858192421217162 0.257457726365149 0.719418000318808 0.719418000318808
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
U2surp ENSMUSG00000032407 0.382391809326972 0.704648147768288 0.469765431845525 0.704648147768288 0.737208398499227 0.737208398499227
Rbm5 ENSMUSG00000032580 0.779270754053549 0.779270754053549 0.467301384838239 0.779270754053549 0.684286646157794 0.779270754053549
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Gcfc2 ENSMUSG00000035125 0.350923631929971 0.655522796195744 0.467316130174812 0.655522796195744 0.655522796195744 0.655522796195744
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Rbmxl1 ENSMUSG00000037070 0.216947576817546 0.535655779262514 0.357103852841676 0.535655779262514 0.652665364959371 0.652665364959371
Rbm17 ENSMUSG00000037197 0.949640762876706 0.949640762876706 0.684204858403164 0.949640762876706 0.641282419372059 0.949640762876706
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Sart1 ENSMUSG00000039148 0.255682116626992 0.383523174940487 0.150285264886121 0.383523174940487 0.846527772540081 0.846527772540081
Srrm2 ENSMUSG00000039218 0.599225711624519 0.818851114514297 0.176834243249748 0.530502729749244 0.818851114514297 0.818851114514297
Hnrnpu ENSMUSG00000039630 0.545644981217212 0.871449753757413 0.755143033014401 0.871449753757413 0.871449753757413 0.871449753757413
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hnrnpul1 ENSMUSG00000040725 0.773129846978817 0.949635296196564 0.937086968663867 0.949635296196564 0.949635296196564 0.949635296196564
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Cd2bp2 ENSMUSG00000042502 0.782245545584187 0.782245545584187 0.512054317172143 0.768081475758215 0.494260435019555 0.768081475758215
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Hnrnph2 ENSMUSG00000045427 0.0887814689864825 0.266344406959447 0.209611303234731 0.314416954852097 0.965363137104306 0.965363137104306
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Dnajc8 ENSMUSG00000054405 0.120258770227668 0.180388155341502 0.119289712862716 0.180388155341502 0.675561509952905 0.675561509952905
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Usp39 ENSMUSG00000056305 0.868237627224644 0.868237627224644 0.501875065011385 0.868237627224644 0.60474327807067 0.868237627224644
Pcbp2 ENSMUSG00000056851 0.77922054163382 0.77922054163382 0.380272711965077 0.77922054163382 0.758120657806994 0.77922054163382
Txnl4a ENSMUSG00000057130 0.236357181189437 0.354535771784155 0.230151656915334 0.354535771784155 0.489307092916846 0.489307092916846
Hnrnpa3 ENSMUSG00000059005 0.105636484960633 0.316909454881898 0.81888866547801 0.921391871133013 0.921391871133013 0.921391871133013
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Snrpa ENSMUSG00000061479 0.534605497823689 0.555609483286124 0.170606409808356 0.511819229425067 0.555609483286124 0.555609483286124
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Snrnp70 ENSMUSG00000063511 0.524782402817906 0.912009745810262 0.912009745810262 0.912009745810262 0.855890115741388 0.912009745810262
Prpf38a ENSMUSG00000063800 0.921406595137766 0.990553841719651 0.380312342168521 0.990553841719651 0.990553841719651 0.990553841719651
Hnrnpr ENSMUSG00000066037 0.90888267515115 0.90888267515115 0.652664168484424 0.90888267515115 0.812796803032516 0.90888267515115
Prpf4 ENSMUSG00000066148 0.828134400170103 0.828134400170103 0.812805235354818 0.828134400170103 0.509420357929062 0.828134400170103
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

mRNA Splicing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.855891963062675 0.930789246918887 0.803626350984924 0.930789246918887 0.930789246918887 0.930789246918887
Sf3a1 ENSMUSG00000002129 0.840438875170834 0.840438875170834 0.728300208308162 0.840438875170834 0.429243825447866 0.840438875170834
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Puf60 ENSMUSG00000002524 0.122126688897098 0.183190033345647 0.0473430856036172 0.142029256810851 0.53779597419782 0.53779597419782
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Cwc15 ENSMUSG00000004096 0.572269538520786 0.865240266985103 0.684298391674831 0.865240266985103 0.865240266985103 0.865240266985103
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prcc ENSMUSG00000004895 0.635599661383936 0.635599661383936 0.0910004551454026 0.273001365436208 0.591238961662756 0.635599661383936
Bcas2 ENSMUSG00000005687 0.862076641749625 0.886958979907288 0.365312252212635 0.886958979907288 0.886958979907288 0.886958979907288
Hnrnpa0 ENSMUSG00000007836 0.230566309369634 0.345849464054451 0.0249571024305369 0.0748713072916106 0.761182380443518 0.761182380443518
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Prpf31 ENSMUSG00000008373 0.927669343869935 0.927669343869935 0.737204864427204 0.927669343869935 0.36741760703245 0.927669343869935
Sugp1 ENSMUSG00000011306 0.274817104073723 0.82445131222117 0.794481324664869 0.990549530945263 0.990549530945263 0.990549530945263
Hnrnpl ENSMUSG00000015165 0.290708711947854 0.624288396551694 0.514383808587368 0.624288396551694 0.624288396551694 0.624288396551694
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Prpf3 ENSMUSG00000015748 0.887020085974762 0.887020085974762 0.803632537244706 0.887020085974762 0.627217570846182 0.887020085974762
Ppil4 ENSMUSG00000015757 0.330691144462917 0.496036716694376 0.31713951747283 0.496036716694376 0.852775108802872 0.852775108802872
Skiv2l2 ENSMUSG00000016018 0.119136042931793 0.357408128795379 0.238396318461405 0.357594477692107 0.877613080915908 0.877613080915908
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Cwc25 ENSMUSG00000018541 0.968514516979504 0.968514516979504 0.812796679924482 0.968514516979504 0.710545147168425 0.968514516979504
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Ddx46 ENSMUSG00000021500 0.136232818526581 0.408698455579741 0.42249855869066 0.63374783803599 0.905713436224748 0.905713436224748
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Cwc27 ENSMUSG00000021715 0.0500840677767623 0.0751261016651435 0.000466158734168928 0.00139847620250679 0.59617013105787 0.59617013105787
Wbp4 ENSMUSG00000022023 0.57767409160757 0.940226722054822 0.81280258883619 0.940226722054822 0.940226722054822 0.940226722054822
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cdc5l ENSMUSG00000023932 0.908822319977401 0.908822319977401 0.218320367929368 0.654961103788104 0.55070490413027 0.826057356195404
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Rbm22 ENSMUSG00000024604 0.558919808180084 0.678487645353992 0.678487645353992 0.678487645353992 0.672727756407916 0.678487645353992
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Sf1 ENSMUSG00000024949 0.996851247529016 0.996851247529016 0.602234646766558 0.996851247529016 0.915140925930742 0.996851247529016
Smndc1 ENSMUSG00000025024 0.965367521438985 0.965367521438985 0.26634545215952 0.799036356478559 0.821988383582378 0.965367521438985
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Ppil3 ENSMUSG00000026035 0.548325476095461 0.838402715883537 0.971666463054836 0.971666463054836 0.558935143922358 0.838402715883537
Cwc22 ENSMUSG00000027014 0.812805789263119 1 0.782304377698204 1 1 1
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Ctnnbl1 ENSMUSG00000027649 0.658377821420181 0.782320636449417 0.782320636449417 0.782320636449417 0.635670240395242 0.782320636449417
Rnpc3 ENSMUSG00000027981 0.496926771619955 0.745390157429933 0.251292362417855 0.745390157429933 0.927676463240204 0.927676463240204
Plrg1 ENSMUSG00000027998 0.68140120643685 0.68140120643685 0.486892343577072 0.68140120643685 0.477018689801654 0.68140120643685
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Sf3a3 ENSMUSG00000028902 0.933947680963532 0.933947680963532 0.87455809977212 0.933947680963532 0.519685402329841 0.933947680963532
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Tfip11 ENSMUSG00000029345 0.443298801485242 0.652587822376045 0.205334332181454 0.616002996544363 0.652587822376045 0.652587822376045
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Wbp11 ENSMUSG00000030216 0.859032843384184 0.859032843384184 0.566928581651813 0.859032843384184 0.719432498480505 0.859032843384184
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Snrpa1 ENSMUSG00000030512 0.269803315688056 0.404704973532084 0.0872801468469727 0.261840440540918 0.585829879420865 0.585829879420865
Fus ENSMUSG00000030795 0.731186084726148 0.937075420383339 0.937075420383339 0.937075420383339 0.779282521387873 0.937075420383339
Gpkow ENSMUSG00000031148 0.128082895227264 0.279110114968284 0.186073409978856 0.279110114968284 0.548333435556311 0.548333435556311
Pqbp1 ENSMUSG00000031157 0.666965418978755 0.719418000318808 0.0858192421217162 0.257457726365149 0.719418000318808 0.719418000318808
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
U2surp ENSMUSG00000032407 0.382391809326972 0.704648147768288 0.469765431845525 0.704648147768288 0.737208398499227 0.737208398499227
Rbm5 ENSMUSG00000032580 0.779270754053549 0.779270754053549 0.467301384838239 0.779270754053549 0.684286646157794 0.779270754053549
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Gcfc2 ENSMUSG00000035125 0.350923631929971 0.655522796195744 0.467316130174812 0.655522796195744 0.655522796195744 0.655522796195744
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Rbmxl1 ENSMUSG00000037070 0.216947576817546 0.535655779262514 0.357103852841676 0.535655779262514 0.652665364959371 0.652665364959371
Rbm17 ENSMUSG00000037197 0.949640762876706 0.949640762876706 0.684204858403164 0.949640762876706 0.641282419372059 0.949640762876706
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Sart1 ENSMUSG00000039148 0.255682116626992 0.383523174940487 0.150285264886121 0.383523174940487 0.846527772540081 0.846527772540081
Srrm2 ENSMUSG00000039218 0.599225711624519 0.818851114514297 0.176834243249748 0.530502729749244 0.818851114514297 0.818851114514297
Hnrnpu ENSMUSG00000039630 0.545644981217212 0.871449753757413 0.755143033014401 0.871449753757413 0.871449753757413 0.871449753757413
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hnrnpul1 ENSMUSG00000040725 0.773129846978817 0.949635296196564 0.937086968663867 0.949635296196564 0.949635296196564 0.949635296196564
Snrnp25 ENSMUSG00000040767 0.144873289929696 0.381892931885658 0.254595287923772 0.381892931885658 0.530061457689675 0.530061457689675
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Cd2bp2 ENSMUSG00000042502 0.782245545584187 0.782245545584187 0.512054317172143 0.768081475758215 0.494260435019555 0.768081475758215
Naa38 ENSMUSG00000044155 0.722373300459036 0.722373300459036 0.599491536329788 0.722373300459036 0.641300531230809 0.722373300459036
Hnrnph2 ENSMUSG00000045427 0.0887814689864825 0.266344406959447 0.209611303234731 0.314416954852097 0.965363137104306 0.965363137104306
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Dnajc8 ENSMUSG00000054405 0.120258770227668 0.180388155341502 0.119289712862716 0.180388155341502 0.675561509952905 0.675561509952905
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Usp39 ENSMUSG00000056305 0.868237627224644 0.868237627224644 0.501875065011385 0.868237627224644 0.60474327807067 0.868237627224644
Pcbp2 ENSMUSG00000056851 0.77922054163382 0.77922054163382 0.380272711965077 0.77922054163382 0.758120657806994 0.77922054163382
Txnl4a ENSMUSG00000057130 0.236357181189437 0.354535771784155 0.230151656915334 0.354535771784155 0.489307092916846 0.489307092916846
Hnrnpa3 ENSMUSG00000059005 0.105636484960633 0.316909454881898 0.81888866547801 0.921391871133013 0.921391871133013 0.921391871133013
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Snrpa ENSMUSG00000061479 0.534605497823689 0.555609483286124 0.170606409808356 0.511819229425067 0.555609483286124 0.555609483286124
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Snrnp70 ENSMUSG00000063511 0.524782402817906 0.912009745810262 0.912009745810262 0.912009745810262 0.855890115741388 0.912009745810262
Prpf38a ENSMUSG00000063800 0.921406595137766 0.990553841719651 0.380312342168521 0.990553841719651 0.990553841719651 0.990553841719651
Hnrnpr ENSMUSG00000066037 0.90888267515115 0.90888267515115 0.652664168484424 0.90888267515115 0.812796803032516 0.90888267515115
Prpf4 ENSMUSG00000066148 0.828134400170103 0.828134400170103 0.812805235354818 0.828134400170103 0.509420357929062 0.828134400170103
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Rarg ENSMUSG00000001288 0.0949507440318001 0.2848522320954 0.577661162633673 0.86649174395051 0.937080448558437 0.937080448558437
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Taco1 ENSMUSG00000001983 0.086484862945857 0.259454588837571 0.815861281163154 0.815861281163154 0.528925419338586 0.793388129007879
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Med6 ENSMUSG00000002679 0.990552165598131 0.990552165598131 0.558936418167482 0.990552165598131 0.672681426758166 0.990552165598131
Med25 ENSMUSG00000002968 0.971653838289879 0.971653838289879 0.908873487166612 0.971653838289879 0.4670905839486 0.971653838289879
Cdk12 ENSMUSG00000003119 0.755162148087285 0.93394600324458 0.67272885843545 0.93394600324458 0.93394600324458 0.93394600324458
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Zfp81 ENSMUSG00000003929 0.921398276173297 0.921398276173297 0.450420982394875 0.921398276173297 0.865197012496934 0.921398276173297
Zfp324 ENSMUSG00000004500 0.927677083266821 0.927677083266821 0.734248202546478 0.927677083266821 0.716448379206918 0.927677083266821
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Trim28 ENSMUSG00000005566 0.0696552212572158 0.208965663771647 0.149279783577451 0.223919675366176 0.56151364795391 0.56151364795391
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ctcf ENSMUSG00000005698 0.481928119997173 0.880785231141268 0.880785231141268 0.880785231141268 0.868318228371637 0.880785231141268
Nr2c2 ENSMUSG00000005893 0.764183193354547 0.877616202117077 0.74011847951785 0.877616202117077 0.877616202117077 0.877616202117077
Ttc5 ENSMUSG00000006288 0.289245761101568 0.797531873832735 0.797531873832735 0.797531873832735 0.591266864698899 0.797531873832735
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Rbm14 ENSMUSG00000006456 0.208168357957752 0.569522474062835 0.504457351146993 0.569522474062835 0.569522474062835 0.569522474062835
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Hipk1 ENSMUSG00000008730 0.0940924963949365 0.28227748918481 0.713539120862588 0.713539120862588 0.684230035763789 0.713539120862588
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Zfp790 ENSMUSG00000011427 0.08725095874565 0.26175287623695 0.431745151093074 0.53262732242229 0.53262732242229 0.53262732242229
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Med15 ENSMUSG00000012114 0.821919378323644 0.893214949965843 0.710574761934654 0.893214949965843 0.893214949965843 0.893214949965843
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Surf1 ENSMUSG00000015790 0.440974576923634 0.661461865385452 0.666963880398388 0.666963880398388 0.422383519581425 0.661461865385452
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Med1 ENSMUSG00000018160 0.176912994511997 0.530738983535992 0.937088643933494 0.937088643933494 0.690096905754397 0.937088643933494
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Zkscan6 ENSMUSG00000018347 0.291057114673061 0.687202073468259 0.678505412905333 0.687202073468259 0.687202073468259 0.687202073468259
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Yeats4 ENSMUSG00000020171 0.658173758986959 0.933918552920911 0.238351538159865 0.715054614479596 0.933918552920911 0.933918552920911
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Med7 ENSMUSG00000020397 0.728213913004377 0.858987230162626 0.203769079948581 0.611307239845742 0.858987230162626 0.858987230162626
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Ppm1d ENSMUSG00000020525 0.624435190288112 0.794447909549847 0.794447909549847 0.794447909549847 0.585774454653853 0.794447909549847
Cox11 ENSMUSG00000020544 0.0434338691683981 0.0651508037525971 1.83822333159272e-06 5.51466999477816e-06 0.324900544328719 0.324900544328719
Rffl ENSMUSG00000020696 0.499406497178666 0.569551782735742 0.309533365572562 0.569551782735742 0.569551782735742 0.569551782735742
Med31 ENSMUSG00000020801 0.613191476590519 0.871411388586427 0.871411388586427 0.871411388586427 0.438725432334298 0.871411388586427
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Ppp1r13b ENSMUSG00000021285 0.707638838245221 0.785353922376112 0.785353922376112 0.785353922376112 0.779270489867307 0.785353922376112
A530054K11Rik ENSMUSG00000021510 0.079401470788274 0.121062123721737 0.0807080824811581 0.121062123721737 0.725217096412423 0.725217096412423
Med10 ENSMUSG00000021598 0.915124101313431 0.915124101313431 0.912007984588996 0.915124101313431 0.537724386371694 0.915124101313431
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Med4 ENSMUSG00000022109 0.594007900130456 0.891011850195685 0.208123102342938 0.624369307028813 0.965367834542043 0.965367834542043
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Zfp263 ENSMUSG00000022529 0.855866014430946 1 0.588496132615472 1 1 1
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Epc1 ENSMUSG00000024240 0.16573552702746 0.497206581082381 0.393337278290945 0.590005917436418 0.632780075332655 0.632780075332655
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Zfp871 ENSMUSG00000024298 0.0398045680509124 0.119413704152737 0.0949677760423197 0.14245166406348 0.770224083518563 0.770224083518563
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Pcgf6 ENSMUSG00000025050 0.758178056805396 0.946510665533973 0.716486625058548 0.946510665533973 0.946510665533973 0.946510665533973
Ldb1 ENSMUSG00000025223 0.410968262589304 0.862094308754716 0.862094308754716 0.862094308754716 0.577562753134684 0.862094308754716
Tbl1x ENSMUSG00000025246 0.949633171970116 0.990551854325694 0.782226920895053 0.990551854325694 0.990551854325694 0.990551854325694
Banp ENSMUSG00000025316 0.352973634799885 0.352973634799885 0.0550155669365745 0.165046700809724 0.313355013846564 0.352973634799885
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Zfp202 ENSMUSG00000025602 0.232141296260803 0.693007696821341 0.693007696821341 0.693007696821341 0.572234447202385 0.693007696821341
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Zfp282 ENSMUSG00000025821 0.86520171122549 0.974808871158847 0.809701439928137 0.974808871158847 0.974808871158847 0.974808871158847
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Gls ENSMUSG00000026103 0.862052724029941 0.993702533374486 0.981097390127074 0.993702533374486 0.993702533374486 0.993702533374486
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Med27 ENSMUSG00000026799 0.188742580635213 0.283113870952819 0.130086868464712 0.283113870952819 0.380314155487782 0.380314155487782
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Notch1 ENSMUSG00000026923 0.322985784663396 0.669767231045251 0.669767231045251 0.669767231045251 0.489406609204599 0.669767231045251
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Tbl1xr1 ENSMUSG00000027630 0.486940143036373 0.730410214554559 0.380216907855341 0.730410214554559 0.971661244333188 0.971661244333188
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Skil ENSMUSG00000027660 0.0918417107601723 0.275525132280517 0.577695864050358 0.57769637430179 0.57769637430179 0.57769637430179
Ccnc ENSMUSG00000028252 0.173136755541683 0.519410266625048 0.474582473879636 0.711873710819454 0.797518469681053 0.797518469681053
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Nrbp1 ENSMUSG00000029148 0.921403988638114 1 1 1 0.269837366248565 0.809512098745694
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Zfp12 ENSMUSG00000029587 0.422465897532989 0.912008816289995 0.740157948518281 0.912008816289995 0.912008816289995 0.912008816289995
Cdk8 ENSMUSG00000029635 0.846634306273708 0.846634306273708 0.746156018411803 0.846634306273708 0.652647960471599 0.846634306273708
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Zfp606 ENSMUSG00000030386 0.687193336158729 0.81892925311892 0.313342433084137 0.81892925311892 0.81892925311892 0.81892925311892
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Zfp626 ENSMUSG00000030604 0.746171241161978 0.955937633582514 0.955937633582514 0.955937633582514 0.359155367155075 0.955937633582514
Tead2 ENSMUSG00000030796 0.902596998516483 0.921382103057572 0.550973178937966 0.921382103057572 0.921382103057572 0.921382103057572
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
G6pdx ENSMUSG00000031400 0.635393278727122 0.924487728862621 0.924487728862621 0.924487728862621 0.564262605828105 0.924487728862621
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Zfp90 ENSMUSG00000031907 0.883903287645641 0.883903287645641 0.704719387396106 0.883903287645641 0.543083039876083 0.883903287645641
Maml2 ENSMUSG00000031925 0.877637040192188 0.877637040192188 0.843497733680374 0.877637040192188 0.344585874854108 0.877637040192188
Med17 ENSMUSG00000031935 0.773233922582795 0.773233922582795 0.75215585817309 0.773233922582795 0.66981399974883 0.773233922582795
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Tcf12 ENSMUSG00000032228 0.18608468481739 0.420199050336649 0.322980092384098 0.420199050336649 0.420199050336649 0.420199050336649
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Mga ENSMUSG00000033943 0.247957790892636 0.603307914405705 0.40220527627047 0.603307914405705 0.632801060084072 0.632801060084072
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Zfp944 ENSMUSG00000033972 0.209644304089903 0.566914450263349 0.411112217202674 0.566914450263349 0.566914450263349 0.566914450263349
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Zfp418 ENSMUSG00000034538 0.14268551345265 0.214028270178975 0.142652524867088 0.214028270178975 0.627237966620823 0.627237966620823
Zfp661 ENSMUSG00000034800 0.477089366826772 0.575003228483636 0.292885080548305 0.575003228483636 0.575003228483636 0.575003228483636
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Cox18 ENSMUSG00000035505 0.388966256857858 0.583449385286787 0.0631197324422958 0.189359197326887 0.770219768862008 0.770219768862008
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Zfp157 ENSMUSG00000036898 0.737229317287235 0.874542761003085 0.22739896474232 0.68219689422696 0.874542761003085 0.874542761003085
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Med30 ENSMUSG00000038622 0.974812698215822 0.974812698215822 0.527451989710235 0.974812698215822 0.949651629146872 0.974812698215822
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Rbpj ENSMUSG00000039191 0.855923261172793 0.855923261172793 0.54306369608504 0.846381237030571 0.564254158020381 0.846381237030571
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Rxrb ENSMUSG00000039656 0.155039132458621 0.232558698687931 0.0843535974343253 0.232558698687931 0.550982840393409 0.550982840393409
Cited2 ENSMUSG00000039910 0.296426512311656 0.296426512311656 0.236651113528526 0.296426512311656 0.261261147442375 0.296426512311656
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Zfp770 ENSMUSG00000040321 0.0421790568296861 0.126537170489058 0.921360891350043 0.921360891350043 0.815769388332954 0.921360891350043
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cdk13 ENSMUSG00000041297 0.350848580104832 0.89949118258729 0.788318112038651 0.89949118258729 0.89949118258729 0.89949118258729
Zfp386 ENSMUSG00000042063 0.719407853271497 0.719407853271497 0.0173090693496571 0.0519272080489714 0.649794999527396 0.719407853271497
Kdm5b ENSMUSG00000042207 0.797529374580581 0.905741884779121 0.43164088085525 0.905741884779121 0.905741884779121 0.905741884779121
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Zfp784 ENSMUSG00000043290 0.102220206720847 0.306660620162542 0.509524073190022 0.764286109785034 0.883887904440387 0.883887904440387
Med26 ENSMUSG00000045248 0.852810083936291 0.871444332045489 0.445628277225206 0.871444332045489 0.871444332045489 0.871444332045489
Zfp688 ENSMUSG00000045251 0.0510429928638419 0.153128978591526 0.472043217252454 0.708064825878682 0.86517801866064 0.86517801866064
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Zfp740 ENSMUSG00000046897 0.215460677507988 0.646382032523965 0.558932463577806 0.834310029896056 0.834310029896056 0.834310029896056
Zfp445 ENSMUSG00000047036 0.382279221650018 0.573418832475027 0.182056555164653 0.546169665493958 0.834248971157118 0.834248971157118
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Zfp738 ENSMUSG00000048280 0.348832321796375 0.511999101472343 0.0786801495968421 0.236040448790526 0.511999101472343 0.511999101472343
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Zfp689 ENSMUSG00000048921 0.746161823092674 0.746161823092674 0.646960744142472 0.746161823092674 0.519698243563037 0.746161823092674
Prmt6 ENSMUSG00000049300 0.965374627946491 0.981108445923553 0.616073215983192 0.981108445923553 0.981108445923553 0.981108445923553
Zfp668 ENSMUSG00000049728 0.728318017081463 0.977954253101518 0.977954253101518 0.977954253101518 0.548222725753309 0.977954253101518
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Zfp61 ENSMUSG00000050605 0.728255393999416 0.80972891649625 0.296433823886353 0.80972891649625 0.80972891649625 0.80972891649625
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Zfp169 ENSMUSG00000050954 0.225956461911946 0.338934692867919 0.151599034348063 0.338934692867919 0.9653745468202 0.9653745468202
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Zfp961 ENSMUSG00000052446 0.313345469879295 0.51343843204474 0.342292288029827 0.51343843204474 0.537618763610479 0.537618763610479
Zfp212 ENSMUSG00000052763 0.0933273760001477 0.279982128000443 0.276778316078644 0.415167474117966 0.646917019555695 0.646917019555695
Yap1 ENSMUSG00000053110 0.180814967855615 0.271222451783422 0.0226891810822577 0.0680675432467731 0.632849896559277 0.632849896559277
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Zfp952 ENSMUSG00000053390 0.984257221868525 0.984257221868525 0.448158705547278 0.984257221868525 0.788397649478662 0.984257221868525
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Zfp867 ENSMUSG00000054519 0.00135825115299108 0.00407475345897325 0.434055483426102 0.434055483426102 0.141618529549119 0.212427794323679
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Zfp78 ENSMUSG00000055150 0.26627947686516 0.472921574890155 0.31528104992677 0.472921574890155 0.669832326835454 0.669832326835454
Zfp101 ENSMUSG00000055240 0.734262482213761 0.734262482213761 0.594012848288838 0.734262482213761 0.556278619594594 0.734262482213761
Zfp457 ENSMUSG00000055341 0.930746361961035 0.930746361961035 0.469074828413572 0.930746361961035 0.680944397078772 0.930746361961035
Zfp459 ENSMUSG00000055560 0.890135106257556 0.911994958053049 0.874544220095528 0.911994958053049 0.911994958053049 0.911994958053049
Zkscan5 ENSMUSG00000055991 0.767196870167699 0.974810879105003 0.974810879105003 0.974810879105003 0.257929357432216 0.773788072296648
Zfp709 ENSMUSG00000056019 0.797521765668082 0.797521765668082 0.443426304833404 0.797521765668082 0.791439214671057 0.797521765668082
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Zfp658 ENSMUSG00000056592 0.228914595980664 0.529448402085402 0.352965601390268 0.529448402085402 0.740145018102158 0.740145018102158
Zfp180 ENSMUSG00000057101 0.635672883009121 0.716491563767633 0.50699756826521 0.716491563767633 0.716491563767633 0.716491563767633
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Zfp759 ENSMUSG00000057396 0.170558669666104 0.255838004499155 0.0613950170147065 0.184185051044119 0.716464382522481 0.716464382522481
Zfp317 ENSMUSG00000057551 0.955937432081627 0.955937432081627 0.350911493675258 0.919893453908227 0.613262302605485 0.919893453908227
Zfp746 ENSMUSG00000057691 0.716416334129172 0.91511973774182 0.690105046205586 0.91511973774182 0.91511973774182 0.91511973774182
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Zfp420 ENSMUSG00000058402 0.155023950321555 0.465071850964665 0.56424187734588 0.56424187734588 0.371750809395157 0.557626214092735
Max ENSMUSG00000059436 0.722392653421377 0.930812666801164 0.855938138929478 0.930812666801164 0.930812666801164 0.930812666801164
Zfp426 ENSMUSG00000059475 0.219940486145568 0.545696630321519 0.545696630321519 0.545696630321519 0.524863157898077 0.545696630321519
Zfp874b ENSMUSG00000059839 0.0310173143234376 0.0930519429703127 0.42943013546867 0.644145203203005 0.794479238099772 0.794479238099772
Zfp74 ENSMUSG00000059975 0.74312652221704 0.846609686576337 0.846609686576337 0.846609686576337 0.610487324547613 0.846609686576337
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Zfp937 ENSMUSG00000060336 0.50693038776156 0.52223685668885 0.371587959673858 0.52223685668885 0.52223685668885 0.52223685668885
Maml3 ENSMUSG00000061143 0.734134168310536 0.828152725615866 0.828152725615866 0.828152725615866 0.752082162914131 0.828152725615866
Zfp873 ENSMUSG00000061371 0.725355719425837 0.902625754780667 0.902625754780667 0.902625754780667 0.296514941101917 0.88954482330575
Zfp229 ENSMUSG00000061544 0.675617394576195 0.788380161701511 0.788380161701511 0.788380161701511 0.153832893418283 0.46149868025485
Zfp954 ENSMUSG00000062116 0.658369028217264 0.959082992771107 0.959081970344945 0.959082992771107 0.959082992771107 0.959082992771107
Zfp706 ENSMUSG00000062397 0.190066273777015 0.285099410665523 0.018087075658525 0.0542612269755749 0.837366899643581 0.837366899643581
Zfp398 ENSMUSG00000062519 0.564185686622195 0.877651726266627 0.849742320769921 0.877651726266627 0.877651726266627 0.877651726266627
Zfp28 ENSMUSG00000062861 0.486832734119497 0.803632902387604 0.803632902387604 0.803632902387604 0.624360129581231 0.803632902387604
Zfp780b ENSMUSG00000063047 0.39107661533431 0.467333115705241 0.467333115705241 0.467333115705241 0.34277150669525 0.467333115705241
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Zfp35 ENSMUSG00000063281 0.115441460058477 0.346324380175432 0.499295440472368 0.748943160708552 0.837307669061056 0.837307669061056
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Zkscan8 ENSMUSG00000063894 0.755157435922603 0.755157435922603 0.280297057034039 0.63035178324964 0.420234522166427 0.63035178324964
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Med14 ENSMUSG00000064127 0.159665944223733 0.4789978326712 0.896381429694953 0.896381429694953 0.740156213379708 0.896381429694953
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Zfp932 ENSMUSG00000066613 0.959072162115386 0.959072162115386 0.519630290172417 0.959072162115386 0.752175376007337 0.959072162115386
Zfp617 ENSMUSG00000066880 0.268096534148183 0.402144801222275 0.108317010074898 0.324951030224694 0.583011859976807 0.583011859976807
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Zfp760 ENSMUSG00000067928 0.48687582265191 0.548295288947333 0.522226293473166 0.548295288947333 0.548295288947333 0.548295288947333
Zfp948 ENSMUSG00000067931 0.0285453743051351 0.0856361229154051 0.195421754963501 0.293132632445251 0.937089239708422 0.937089239708422
Zfp160 ENSMUSG00000067942 0.924541399094157 0.924541399094157 0.249662670833093 0.748988012499278 0.610522750033069 0.915784125049603
Zfp442 ENSMUSG00000068130 0.334710899073492 0.502066348610238 0.178194264925847 0.502066348610238 0.537804113289125 0.537804113289125
Zfp120 ENSMUSG00000068134 0.828151554474058 0.828151554474058 0.445754607281558 0.828151554474058 0.825056118712257 0.828151554474058
Zfp467 ENSMUSG00000068551 0.672505367288898 0.701629588633727 0.701629588633727 0.701629588633727 0.106981150107606 0.320943450322817
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Gm5595 ENSMUSG00000069727 0.150466132955774 0.225699199433661 0.0696380933388098 0.208914280016429 0.737238389965789 0.737238389965789
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Zscan25 ENSMUSG00000070420 0.162071713401021 0.486215140203062 0.737235846318888 0.737235846318888 0.572289335338048 0.737235846318888
1700049G17Rik ENSMUSG00000070709 0.684297290588225 0.74319910385997 0.328836522252172 0.74319910385997 0.74319910385997 0.74319910385997
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Zfp213 ENSMUSG00000071256 0.448148041703337 0.672709536904298 0.672709536904298 0.672709536904298 0.5589248616806 0.672709536904298
Zfp942 ENSMUSG00000071267 0.0413590765633997 0.124077229690199 0.106407235061891 0.159610852592837 0.643989625953818 0.643989625953818
Zfp71-rs1 ENSMUSG00000071281 0.320955744765794 0.43629926817455 0.252950895013197 0.43629926817455 0.43629926817455 0.43629926817455
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Rybp ENSMUSG00000072872 0.386764557826432 0.580146836739649 0.382296177582122 0.580146836739649 0.849676161042615 0.849676161042615
Gm4924 ENSMUSG00000073427 0.635566340219901 0.646962472199323 0.638409895415124 0.646962472199323 0.646962472199323 0.646962472199323
Zfp94 ENSMUSG00000074282 0.395556967321084 0.604948942256054 0.604948942256054 0.604948942256054 0.43866682563663 0.604948942256054
Etohi1 ENSMUSG00000074519 0.00555732722459425 0.0166719816737827 0.0941805625037277 0.141270843755592 0.610438439112846 0.610438439112846
5830428H23Rik ENSMUSG00000074733 0.613252782036663 0.613252782036663 0.128961433513013 0.364701914375926 0.24313460958395 0.364701914375926
Zfp934 ENSMUSG00000074865 0.602222434294486 0.602222434294486 0.545641118059147 0.602222434294486 0.395520999333589 0.602222434294486
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
AU041133 ENSMUSG00000078435 0.532559173816322 0.532559173816322 0.107365303535444 0.322095910606332 0.375840048285497 0.532559173816322
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Zfp566 ENSMUSG00000078768 0.311349031679773 0.770198117090135 0.770181200504567 0.770198117090135 0.770198117090135 0.770198117090135
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Zfp703 ENSMUSG00000085795 0.899499086347557 0.899499086347557 0.610502006548519 0.899499086347557 0.268105013405796 0.804315040217388
Zfp882 ENSMUSG00000089857 0.138355094383173 0.415065283149518 0.849731095697754 0.849731095697754 0.332711815049975 0.499067722574962
Gm15446 ENSMUSG00000090015 0.158543303459984 0.273187033932232 0.182124689288155 0.273187033932232 0.524868302216941 0.524868302216941
Gm5141 ENSMUSG00000091183 0.728251981722718 0.785346672713238 0.785346672713238 0.785346672713238 0.529811219353198 0.785346672713238
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
2610021A01Rik ENSMUSG00000091474 0.0496472342066872 0.148941702620062 0.1596840208813 0.23952603132195 0.716487655240011 0.716487655240011
Zfp963 ENSMUSG00000092260 0.149247241613784 0.447741724841352 0.984253468681904 0.984253468681904 0.943367928879089 0.984253468681904
Med20 ENSMUSG00000092558 0.937078933921258 0.937078933921258 0.82504823661484 0.937078933921258 0.566945182108028 0.937078933921258
Gm4767 ENSMUSG00000094076 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp955a ENSMUSG00000094441 0.591268108386733 0.591268108386733 0.0460158911431359 0.138047673429408 0.431674183344687 0.591268108386733
Gm3604 ENSMUSG00000094942 0.968518933881967 0.968518933881967 0.44098731046428 0.830429198731452 0.553619465820968 0.830429198731452
Zfp870 ENSMUSG00000095325 0.80968410981223 0.80968410981223 0.422411415597203 0.633617123395805 0.296455215798333 0.633617123395805
Zfp748 ENSMUSG00000095432 0.29287279987543 0.45309017495156 0.302060116634373 0.45309017495156 0.569620779197383 0.569620779197383
Zfp960 ENSMUSG00000096696 0.782323385382656 0.782323385382656 0.10386320132676 0.31158960398028 0.564075420300437 0.782323385382656
Gm10778 ENSMUSG00000096856 0.865229162860011 0.865229162860011 0.431678822555258 0.647518233832887 0.367372842128871 0.647518233832887
Zfp87 ENSMUSG00000097333 0.307373830560574 0.461060745840861 0.0495595649496402 0.148678694848921 0.868301084753766 0.868301084753766

Post-translational protein modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Fbxo9 ENSMUSG00000001366 0.213593913192257 0.460696954000312 0.307131302666875 0.460696954000312 0.940194121838634 0.940194121838634
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ltbp1 ENSMUSG00000001870 0.145732705713255 0.218599058569882 0.13401768964257 0.218599058569882 0.669488011967337 0.669488011967337
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Hltf ENSMUSG00000002428 0.469559400197792 0.783035674339656 0.522023782893104 0.783035674339656 0.984253887202867 0.984253887202867
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Dnmt1 ENSMUSG00000004099 0.577555858074608 0.635538036514718 0.457685292289755 0.635538036514718 0.635538036514718 0.635538036514718
Etfb ENSMUSG00000004610 0.218445427241135 0.461545761682517 0.307697174455011 0.461545761682517 0.704725234059946 0.704725234059946
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Ufd1l ENSMUSG00000005262 0.591252229789365 0.591252229789365 0.328797396458557 0.591252229789365 0.434033727036496 0.591252229789365
Fbxo11 ENSMUSG00000005371 0.229006001463732 0.687018004391197 0.610471723108175 0.915707584662263 0.933935404170617 0.933935404170617
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Rcn1 ENSMUSG00000005973 0.82200644313783 0.930810925390078 0.930810925390078 0.930810925390078 0.791431774351367 0.930810925390078
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Usp19 ENSMUSG00000006676 0.555985360729751 0.743015676480996 0.092602981624798 0.277808944874394 0.743015676480996 0.743015676480996
Stambp ENSMUSG00000006906 0.684279337916864 0.684279337916864 0.681389164199228 0.684279337916864 0.574989725969528 0.684279337916864
Man1a2 ENSMUSG00000008763 0.330822217752787 0.877668439988077 0.71351773942311 0.877668439988077 0.877668439988077 0.877668439988077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Dhdds ENSMUSG00000012117 0.380096767525911 0.486885228563667 0.156177897574698 0.468533692724093 0.486885228563667 0.486885228563667
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Pigl ENSMUSG00000014245 0.713504308576772 0.977959476008201 0.977959476008201 0.977959476008201 0.602166388613618 0.977959476008201
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Csf1 ENSMUSG00000014599 0.574954724567226 0.574954724567226 0.494298023183587 0.574954724567226 0.408900775788184 0.574954724567226
Adamts13 ENSMUSG00000014852 0.809733209937742 0.809733209937742 0.367542031152541 0.551313046728812 0.222939063628633 0.551313046728812
Fbxw5 ENSMUSG00000015095 0.312266225489717 0.583363918635638 0.388909279090426 0.583363918635638 0.818437948865218 0.818437948865218
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Ttll12 ENSMUSG00000016757 0.521582816542189 0.782374224813284 0.045553811953198 0.136661435859594 0.921279616743216 0.921279616743216
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Top2b ENSMUSG00000017485 0.621570154742956 0.970443928900233 0.646962619266822 0.970443928900233 0.977954326966792 0.977954326966792
Wsb1 ENSMUSG00000017677 0.692964035503656 0.767165274931203 0.621531949939947 0.767165274931203 0.767165274931203 0.767165274931203
Pigt ENSMUSG00000017721 0.698534474020628 0.752174519354127 0.752174519354127 0.752174519354127 0.618477155240358 0.752174519354127
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Uchl5 ENSMUSG00000018189 0.219896114839815 0.525896260581595 0.350597507054397 0.525896260581595 0.76099969924541 0.76099969924541
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Fkbp8 ENSMUSG00000019428 0.0754988039267296 0.226496411780189 0.397661585885481 0.501093706078811 0.501093706078811 0.501093706078811
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Cand1 ENSMUSG00000020114 0.532628880282576 0.588494256711568 0.266363632771176 0.588494256711568 0.588494256711568 0.588494256711568
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Cpm ENSMUSG00000020183 0.179516777192962 0.538550331578887 0.971665919177245 0.971665919177245 0.624416526131332 0.936624789196999
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Pofut2 ENSMUSG00000020260 0.946504958272519 0.946504958272519 0.186082311197214 0.558246933591641 0.887002277265015 0.946504958272519
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Fstl3 ENSMUSG00000020325 0.543073977005065 0.814610965507597 0.438611788619754 0.814610965507597 0.962216658625427 0.962216658625427
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Fam20a ENSMUSG00000020614 0.363259287972013 0.544888931958019 0.328847738563471 0.544888931958019 0.797521124179864 0.797521124179864
Rnf144a ENSMUSG00000020642 0.785340357892338 0.785340357892338 0.448119551026687 0.704626611701217 0.469751074467478 0.704626611701217
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Fbxl20 ENSMUSG00000020883 0.443360548542608 0.72231253977434 0.599400170065276 0.72231253977434 0.72231253977434 0.72231253977434
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Fut8 ENSMUSG00000021065 0.800516224830663 0.933931185203149 0.933931185203149 0.933931185203149 0.504470362618556 0.933931185203149
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Pigh ENSMUSG00000021120 0.486923236887201 0.840470186112147 0.831219976620384 0.840470186112147 0.840470186112147 0.840470186112147
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Traf3 ENSMUSG00000021277 0.996851024285757 0.996851024285757 0.50951720821185 0.996851024285757 0.974813654004815 0.996851024285757
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Atxn7 ENSMUSG00000021738 0.300230842914402 0.900692528743205 0.773245376445156 0.921407802086672 0.921407802086672 0.921407802086672
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Bap1 ENSMUSG00000021901 0.413407788783879 0.620111683175819 0.108343937037946 0.325031811113838 0.797530303516965 0.797530303516965
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Dcaf11 ENSMUSG00000022214 0.222574410264143 0.333861615396215 0.128980740980393 0.333861615396215 0.499343826799581 0.499343826799581
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Josd1 ENSMUSG00000022426 0.883902927272286 0.883902927272286 0.0386462576960662 0.115938773088198 0.72239476386854 0.883902927272286
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Gpaa1 ENSMUSG00000022561 0.140166511072528 0.210249766608792 0.0554643222446901 0.16639296673407 0.41514481101606 0.41514481101606
Arsa ENSMUSG00000022620 0.388495581244411 0.743086024725586 0.743086024725586 0.743086024725586 0.604707419688747 0.743086024725586
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Senp5 ENSMUSG00000022772 0.322987682059722 0.803627553914552 0.803627553914552 0.803627553914552 0.627228423353243 0.803627553914552
B4galt4 ENSMUSG00000022793 0.556279987782527 0.846657138693467 0.803630539662222 0.846657138693467 0.846657138693467 0.846657138693467
Senp2 ENSMUSG00000022855 0.318959073507393 0.523070923993142 0.348713949328761 0.523070923993142 0.924493561362545 0.924493561362545
App ENSMUSG00000022892 0.669837081661211 0.704724196773938 0.332776383296367 0.704724196773938 0.704724196773938 0.704724196773938
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Satb1 ENSMUSG00000023927 0.94651011695288 0.971665729445135 0.803624675438964 0.971665729445135 0.971665729445135 0.971665729445135
Spsb3 ENSMUSG00000024160 0.0132113072544738 0.0198169608817108 0.00050144460873919 0.00150433382621757 0.460065964929223 0.460065964929223
Wac ENSMUSG00000024283 0.0434174539866481 0.130252361959944 0.429356293987237 0.452649977383344 0.452649977383344 0.452649977383344
Adamts10 ENSMUSG00000024299 0.424804857545353 0.63720728631803 0.666976433193722 0.666976433193722 0.276657056968397 0.63720728631803
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Otub1 ENSMUSG00000024767 0.2998765079153 0.2998765079153 0.185928139933512 0.2998765079153 0.250990052949487 0.2998765079153
Stambpl1 ENSMUSG00000024776 0.927676382716097 0.927676382716097 0.749167566537165 0.927676382716097 0.737218377949268 0.927676382716097
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Uhrf2 ENSMUSG00000024817 0.915142256744398 0.915142256744398 0.649828919527377 0.915142256744398 0.550973357034918 0.915142256744398
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Rce1 ENSMUSG00000024889 0.556266879142241 0.834400318713362 0.110081838544872 0.330245515634615 0.990553944009068 0.990553944009068
Smc5 ENSMUSG00000024943 0.450479271527473 0.661222470513607 0.535252137809611 0.661222470513607 0.661222470513607 0.661222470513607
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Fbxl15 ENSMUSG00000025226 0.307695222968975 0.461542834453462 0.00805888483641587 0.0241766545092476 0.859033170480059 0.859033170480059
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Mbd6 ENSMUSG00000025409 0.678201875842515 0.962204370529384 0.162065246181141 0.486195738543423 0.962204370529384 0.962204370529384
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Usp33 ENSMUSG00000025437 0.491903194177525 0.737854791266288 0.908875584338405 0.908875584338405 0.484443431720096 0.737854791266288
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumf2 ENSMUSG00000025538 0.361255356494241 0.363313512054046 0.363313512054046 0.363313512054046 0.361153066976894 0.363313512054046
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Usp16 ENSMUSG00000025616 0.641287562523823 0.641287562523823 0.261021554656134 0.641287562523823 0.632763573931717 0.641287562523823
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Pigq ENSMUSG00000025728 0.927450586533143 0.927450586533143 0.264110142204604 0.611288452668792 0.407525635112528 0.611288452668792
Rab40c ENSMUSG00000025730 0.479507075557809 0.632857723789703 0.324918595984423 0.632857723789703 0.632857723789703 0.632857723789703
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Mettl21a ENSMUSG00000025956 0.0229191695117259 0.0451236422004621 0.0300824281336414 0.0451236422004621 0.564231120020121 0.564231120020121
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Asb1 ENSMUSG00000026311 0.601944165244773 0.601944165244773 0.0636532260572407 0.190959678171722 0.454867103954538 0.601944165244773
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Klhl20 ENSMUSG00000026705 0.519684141499169 0.695920118882848 0.496896837138848 0.695920118882848 0.695920118882848 0.695920118882848
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Dpm2 ENSMUSG00000026810 0.324494861834532 0.50685771288579 0.50685771288579 0.50685771288579 0.365213878733351 0.50685771288579
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Dnajc24 ENSMUSG00000027166 0.420243883171676 0.630365824757515 0.36328916929203 0.630365824757515 0.87144282352072 0.87144282352072
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Rab22a ENSMUSG00000027519 0.334492115394274 0.501738173091411 0.112535666740065 0.337607000220194 0.782169427079697 0.782169427079697
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Dcun1d1 ENSMUSG00000027708 8.10795627050442e-05 0.000243238688115133 0.0182788203713412 0.0274182305570119 0.695670533376091 0.695670533376091
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Slc35a1 ENSMUSG00000028293 0.499420937815872 0.749131406723807 0.268064332008418 0.749131406723807 0.962229010589356 0.962229010589356
Rnf20 ENSMUSG00000028309 0.76415898641512 0.924530595215217 0.924530595215217 0.924530595215217 0.865241638042382 0.924530595215217
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Reck ENSMUSG00000028476 0.460074096095066 0.588529060989998 0.588529060989998 0.588529060989998 0.344799360838209 0.588529060989998
Usp24 ENSMUSG00000028514 0.80665519534199 0.874551056307771 0.326891407506396 0.874551056307771 0.874551056307771 0.874551056307771
Dph2 ENSMUSG00000028540 0.40659325300947 0.609889879514204 0.406532933640389 0.609889879514204 0.627198287996468 0.627198287996468
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Pomgnt1 ENSMUSG00000028700 0.27138211417777 0.407073171266655 0.194158081615569 0.407073171266655 0.85278350120545 0.85278350120545
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Nub1 ENSMUSG00000028954 0.315243633036749 0.764183193354547 0.537847393351677 0.764183193354547 0.764183193354547 0.764183193354547
Park7 ENSMUSG00000028964 0.100193509532914 0.300580528598743 0.340072180267643 0.501892715742569 0.501892715742569 0.501892715742569
Pex14 ENSMUSG00000028975 0.194171505737175 0.291257258605763 0.080828462166762 0.242485386500286 0.971666162661201 0.971666162661201
Tada2b ENSMUSG00000029196 0.406557368296659 0.693030382940719 0.693030382940719 0.693030382940719 0.610435525360737 0.693030382940719
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Commd8 ENSMUSG00000029213 0.821925131826797 0.862093652847388 0.690103864566942 0.862093652847388 0.862093652847388 0.862093652847388
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Usp12 ENSMUSG00000029640 0.779285739065985 0.915135318836707 0.862138477061457 0.915135318836707 0.915135318836707 0.915135318836707
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Sspo ENSMUSG00000029797 0.623658794367673 0.724206646260712 0.376101610579076 0.724206646260712 0.724206646260712 0.724206646260712
Fbxl14 ENSMUSG00000030019 0.585733426897513 0.878600140346269 0.296343958092929 0.878600140346269 0.912009716457441 0.912009716457441
Kbtbd8 ENSMUSG00000030031 0.566939894440354 0.737225190462243 0.737225190462243 0.737225190462243 0.707644415368941 0.737225190462243
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Sumf1 ENSMUSG00000030101 0.837371323658567 0.837371323658567 0.580355798372116 0.837371323658567 0.50951488825813 0.837371323658567
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Rad18 ENSMUSG00000030254 0.274811771450367 0.577392108098863 0.450487835959263 0.577392108098863 0.577392108098863 0.577392108098863
Ttll3 ENSMUSG00000030276 0.239995701502962 0.6828364895035 0.818901488714662 0.818901488714662 0.455224326335667 0.6828364895035
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Prmt3 ENSMUSG00000030505 0.593991322486657 0.890986983729985 0.178245336869303 0.534736010607908 0.918269479210841 0.918269479210841
Asb7 ENSMUSG00000030509 0.886996648412827 0.886996648412827 0.722376332987625 0.886996648412827 0.855908935982981 0.886996648412827
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Mfge8 ENSMUSG00000030605 0.198245467661143 0.297368201491715 0.0843686667435072 0.253106000230521 0.413374383737894 0.413374383737894
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Fbxl19 ENSMUSG00000030811 0.859032111304213 0.859032111304213 0.624401770964706 0.859032111304213 0.821993934939889 0.859032111304213
Rnf40 ENSMUSG00000030816 0.322848210432661 0.603267145078526 0.402178096719017 0.603267145078526 0.930785590716957 0.930785590716957
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Mettl10 ENSMUSG00000030960 0.752156340150425 0.794463687823316 0.350889481311581 0.794463687823316 0.794463687823316 0.794463687823316
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Ccdc22 ENSMUSG00000031143 0.607550712820628 0.607550712820628 0.215418375774768 0.607550712820628 0.599239281039663 0.607550712820628
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Chrdl1 ENSMUSG00000031283 0.655453404014524 0.915114154789103 0.535203850136679 0.915114154789103 0.915114154789103 0.915114154789103
Glt28d2 ENSMUSG00000031286 0.831144980850077 0.949621753864074 0.949621753864074 0.949621753864074 0.678099586980704 0.949621753864074
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Amfr ENSMUSG00000031751 0.160598941935287 0.24089841290293 0.00166099377824492 0.00498298133473477 0.98739575239825 0.98739575239825
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Usp10 ENSMUSG00000031826 0.431196316155006 0.704660933121012 0.704660933121012 0.704660933121012 0.658011866762809 0.704660933121012
Mbtps1 ENSMUSG00000031835 0.126737032857096 0.380211098571289 0.417920674420203 0.626881011630305 0.722195456436019 0.722195456436019
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Nae1 ENSMUSG00000031878 0.825080834674905 0.834312035461909 0.386783536357782 0.834312035461909 0.834312035461909 0.834312035461909
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Alg9 ENSMUSG00000032059 0.865216430727327 0.865216430727327 0.0872328677294176 0.261698603188253 0.728305688303467 0.865216430727327
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Commd4 ENSMUSG00000032299 0.0734255678782446 0.220276703634734 0.411089384112583 0.596699420845023 0.596699420845023 0.596699420845023
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Usp4 ENSMUSG00000032612 0.476276255657081 0.669269987649272 0.213927345158588 0.641782035475763 0.669269987649272 0.669269987649272
Sbspon ENSMUSG00000032719 0.638684234808694 0.848784859375415 0.0553413172599474 0.166023951779842 0.848784859375415 0.848784859375415
Folr2 ENSMUSG00000032725 0.352129641827052 0.579309440947877 0.386206293965251 0.579309440947877 0.815833467125827 0.815833467125827
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Ttll4 ENSMUSG00000033257 0.725349744051266 0.899502702700766 0.855937088886064 0.899502702700766 0.899502702700766 0.899502702700766
Fem1c ENSMUSG00000033319 0.908878957745757 0.908878957745757 0.266370389855722 0.799111169567166 0.728297759692514 0.908878957745757
Usp37 ENSMUSG00000033364 0.157368156181812 0.472104468545437 0.940226488909329 0.940226488909329 0.834308461857482 0.940226488909329
Fuk ENSMUSG00000033703 0.202504121652905 0.303756182479357 0.110117431939355 0.303756182479357 0.831224840369681 0.831224840369681
Alg3 ENSMUSG00000033809 0.0337267523379115 0.0545486602768248 0.0363657735178832 0.0545486602768248 0.454677354933429 0.454677354933429
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Tpst1 ENSMUSG00000034118 0.225838125044132 0.338757187566199 0.159632371164343 0.338757187566199 0.486888786106925 0.486888786106925
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Nagk ENSMUSG00000034744 0.132873937161566 0.398621811484697 0.58561417216832 0.644087090424569 0.644087090424569 0.644087090424569
Rab24 ENSMUSG00000034789 0.548039956007639 0.822059934011459 0.402099592875922 0.822059934011459 0.946462875743045 0.946462875743045
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
Ntng2 ENSMUSG00000035513 0.937054446139716 0.937054446139716 0.704594261107055 0.937054446139716 0.743058341350706 0.937054446139716
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Adamtsl2 ENSMUSG00000036040 0.818933743512121 0.818933743512121 0.151599816859915 0.454799450579745 0.621645127359781 0.818933743512121
Mgat5 ENSMUSG00000036155 0.61329363619444 0.927676688706274 0.927676688706274 0.927676688706274 0.773241361632843 0.927676688706274
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Cyld ENSMUSG00000036712 0.893249471687713 0.98110763185907 0.773243036549786 0.98110763185907 0.98110763185907 0.98110763185907
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Satb2 ENSMUSG00000038331 0.701180780170431 0.949531112457672 0.949531112457672 0.949531112457672 0.727458227478397 0.949531112457672
Pigu ENSMUSG00000038383 0.176926134305675 0.530778402917025 0.883880384398204 0.883880384398204 0.610420955622581 0.883880384398204
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Otud7b ENSMUSG00000038495 0.655377085525873 0.849652001261297 0.669727460305022 0.849652001261297 0.849652001261297 0.849652001261297
Josd2 ENSMUSG00000038695 0.320854786789104 0.320854786789104 0.012772647551706 0.038317942655118 0.221300509313193 0.320854786789104
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Adrm1 ENSMUSG00000039041 0.104965021816539 0.157447532724809 0.0397463098480413 0.119238929544124 0.571749204282725 0.571749204282725
Pigk ENSMUSG00000039047 0.758182007536299 0.758182007536299 0.62163877745223 0.758182007536299 0.719426675472166 0.758182007536299
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Fn3krp ENSMUSG00000039253 0.556039744282312 0.643957639015951 0.186075932013599 0.558227796040798 0.643957639015951 0.643957639015951
Foxk2 ENSMUSG00000039275 0.49692369178867 0.815866894959488 0.815866894959488 0.815866894959488 0.800575809275715 0.815866894959488
Alg1 ENSMUSG00000039427 0.238169764923128 0.238169764923128 0.0288573539356085 0.0865720618068256 0.213940154501969 0.238169764923128
Asb6 ENSMUSG00000039483 0.918255734950225 0.918255734950225 0.862104557997622 0.918255734950225 0.692981424119149 0.918255734950225
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Fbxl5 ENSMUSG00000039753 0.460089905660059 0.527349966742554 0.382374381325839 0.527349966742554 0.527349966742554 0.527349966742554
Spsb1 ENSMUSG00000039911 0.319080089631295 0.580187025826347 0.865240833296443 0.865240833296443 0.386791350550898 0.580187025826347
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Klhl42 ENSMUSG00000040102 0.472026108099081 0.868301215980349 0.868301215980349 0.868301215980349 0.776168664106968 0.868301215980349
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Manea ENSMUSG00000040520 0.328803574646066 0.455025853771683 0.316806879814107 0.455025853771683 0.455025853771683 0.455025853771683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
St8sia4 ENSMUSG00000040710 0.818878583905477 0.965369500416752 0.965369500416752 0.965369500416752 0.585685930180055 0.965369500416752
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Fbxw4 ENSMUSG00000040913 0.0822124854277177 0.224008023834634 0.149338682556422 0.224008023834634 0.707633447761154 0.707633447761154
Ccdc8 ENSMUSG00000041117 0.722333779317285 0.722333779317285 0.522286127004673 0.722333779317285 0.537725250716463 0.722333779317285
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Pigs ENSMUSG00000041958 0.420220167764266 0.630330251646399 0.141622561647642 0.424867684942927 0.984256431021961 0.984256431021961
Mat2b ENSMUSG00000042032 0.42020009065683 0.630300135985245 0.908878380342246 0.908878380342246 0.411153687199577 0.630300135985245
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Asxl1 ENSMUSG00000042548 0.408861338264557 0.930794506513674 0.710447901186555 0.930794506513674 0.930794506513674 0.930794506513674
Commd10 ENSMUSG00000042705 0.333975226661427 0.797307701580356 0.797307701580356 0.797307701580356 0.577357289469794 0.797307701580356
Usp48 ENSMUSG00000043411 0.675576381154849 0.779281728953017 0.459996534139036 0.779281728953017 0.779281728953017 0.779281728953017
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Adamts6 ENSMUSG00000046169 0.9779273142477 0.9779273142477 0.338466900336666 0.513582561214954 0.342388374143303 0.513582561214954
Yod1 ENSMUSG00000046404 0.159663361778729 0.477072661212058 0.477072661212058 0.477072661212058 0.388914696094678 0.477072661212058
B3gntl1 ENSMUSG00000046605 0.100606323949638 0.301818971848914 0.921403183894556 0.921403183894556 0.386599473615831 0.579899210423747
Ckap4 ENSMUSG00000046841 0.646976442792832 0.79143832733529 0.321052539934727 0.79143832733529 0.79143832733529 0.79143832733529
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Dcun1d3 ENSMUSG00000048787 0.0446830301930137 0.134049090579041 0.522239834738647 0.783359752107971 0.94336638862497 0.94336638862497
Tada3 ENSMUSG00000048930 0.445386787053696 0.668080180580543 0.127981844316683 0.383945532950048 0.893137831012048 0.893137831012048
Dcaf7 ENSMUSG00000049354 0.779251754242924 0.890124914594691 0.298363761411075 0.890124914594691 0.890124914594691 0.890124914594691
Mettl21d ENSMUSG00000049882 0.457460368111691 0.692903445365971 0.692903445365971 0.692903445365971 0.583029679454939 0.692903445365971
Usp42 ENSMUSG00000051306 0.517173520468805 0.852835531331225 0.669841315712961 0.852835531331225 0.852835531331225 0.852835531331225
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
B3galtl ENSMUSG00000051950 0.905749343806834 0.908883677861065 0.908883677861065 0.908883677861065 0.887014572566288 0.908883677861065
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
B4galt3 ENSMUSG00000052423 0.555852678813415 0.833779018220122 0.981105507625407 0.981105507625407 0.481717689407786 0.833779018220122
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
St6galnac3 ENSMUSG00000052544 0.457673821176896 0.686510731765344 0.927671188342965 0.927671188342965 0.246407613661978 0.686510731765344
Gan ENSMUSG00000052557 0.313344114171842 0.470016171257763 0.26299500485965 0.470016171257763 0.681391720765928 0.681391720765928
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435
Rab4b ENSMUSG00000053291 0.484474264461291 0.613292882690895 0.613292882690895 0.613292882690895 0.496911756913925 0.613292882690895
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ubxn7 ENSMUSG00000053774 0.378158472049596 0.708274209461876 0.472182806307917 0.708274209461876 0.943363017302423 0.943363017302423
Fpgt ENSMUSG00000053870 0.290907432114314 0.50798959574374 0.338659730495827 0.50798959574374 0.755157091765088 0.755157091765088
Nanp ENSMUSG00000053916 0.874426704515627 0.987391425325871 0.987391425325871 0.987391425325871 0.286465426520232 0.859396279560696
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Adam10 ENSMUSG00000054693 0.613194850137555 0.613194850137555 0.388947779275199 0.613194850137555 0.530026456466922 0.613194850137555
Klhl5 ENSMUSG00000054920 0.441023563137958 0.556142046462253 0.540328093857368 0.556142046462253 0.556142046462253 0.556142046462253
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Ddx17 ENSMUSG00000055065 0.828152914507463 0.871447107023116 0.871447107023116 0.871447107023116 0.489429050732231 0.871447107023116
Fbxo6 ENSMUSG00000055401 0.165725488149896 0.344494721839957 0.307467389409342 0.344494721839957 0.344494721839957 0.344494721839957
Klhl25 ENSMUSG00000055652 0.0531566348600952 0.159469904580285 0.219797201332521 0.329695801998782 0.342050703942181 0.342050703942181
Gpc3 ENSMUSG00000055653 0.933951116944975 0.933951116944975 0.41796334423776 0.933951116944975 0.818935174009707 0.933951116944975
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Socs6 ENSMUSG00000056153 0.420212053945563 0.803600482650626 0.585800975843989 0.803600482650626 0.803600482650626 0.803600482650626
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Foxk1 ENSMUSG00000056493 0.90262961659103 0.971667329399804 0.971667329399804 0.971667329399804 0.912012543977666 0.971667329399804
Apol8 ENSMUSG00000056656 0.784633163944802 0.803972950501445 0.625700232844416 0.803972950501445 0.803972950501445 0.803972950501445
Commd7 ENSMUSG00000056941 0.652676785235519 0.987405591197671 0.987405591197671 0.987405591197671 0.740221145448748 0.987405591197671
Dph6 ENSMUSG00000057147 0.208146752517076 0.312220128775613 0.0981750414524178 0.294525124357253 0.821996651788269 0.821996651788269
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Nsmce2 ENSMUSG00000059586 0.424673594011485 0.655411431505958 0.556173761323834 0.655411431505958 0.655411431505958 0.655411431505958
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Dhps ENSMUSG00000060038 0.151546602836817 0.45463980851045 0.334760175682778 0.502140263524168 0.644125113609677 0.644125113609677
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mysm1 ENSMUSG00000062627 0.402165611878691 0.603248417818037 0.233701829303918 0.603248417818037 0.675609193134516 0.675609193134516
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Fbxl12 ENSMUSG00000066892 0.514569590928347 0.771854386392521 0.968518283937401 0.968518283937401 0.404276434285822 0.771854386392521
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
B3gnt9 ENSMUSG00000069920 0.556264495629011 0.710538444756707 0.710538444756707 0.710538444756707 0.241580920278622 0.710538444756707
Ndnl2 ENSMUSG00000070520 0.655479660571186 0.776254822726478 0.190002999328858 0.570008997986575 0.776254822726478 0.776254822726478
Top1 ENSMUSG00000070544 0.0524875749189175 0.157462724756753 0.865185136694549 0.981099842312976 0.981099842312976 0.981099842312976
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Camkmt ENSMUSG00000071037 0.51204997609742 0.76807496414613 0.489425553543675 0.76807496414613 0.990552829191558 0.990552829191558
Safb ENSMUSG00000071054 0.574823745567258 0.883875670750215 0.825027507382374 0.883875670750215 0.883875670750215 0.883875670750215
Pgap1 ENSMUSG00000073678 0.434024879763406 0.818907750235861 0.553616938893275 0.818907750235861 0.818907750235861 0.818907750235861
Alg6 ENSMUSG00000073792 0.968509806380037 0.968509806380037 0.902606179045671 0.968509806380037 0.548297525238618 0.968509806380037
Dda1 ENSMUSG00000074247 0.758049932577639 0.959057354226814 0.616040528394896 0.959057354226814 0.959057354226814 0.959057354226814
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Dolk ENSMUSG00000075419 0.0148011689873284 0.0148011689873284 2.65654703682613e-05 7.96964111047838e-05 0.0119531327006982 0.0148011689873284
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Dph1 ENSMUSG00000078789 0.0998175001638427 0.256261059321669 0.232132913023625 0.256261059321669 0.256261059321669 0.256261059321669
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074
Dpm1 ENSMUSG00000078919 0.0409862603823654 0.0614793905735481 0.0180882720006123 0.0542648160018368 0.937087214004604 0.937087214004604
Pigb ENSMUSG00000079469 0.937071267899132 0.937071267899132 0.424778166119504 0.654357997262867 0.436238664841912 0.654357997262867
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Shprh ENSMUSG00000090112 0.561578278019075 0.561578278019075 0.378124993618767 0.561578278019075 0.330806941366433 0.561578278019075
Fbxw10 ENSMUSG00000090173 0.74415417304833 0.74415417304833 0.635518344743522 0.74415417304833 0.729025476397157 0.74415417304833
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298
Gm20716 ENSMUSG00000093752 0.83425163601779 0.83425163601779 0.545583608319016 0.83425163601779 0.7431635404496 0.83425163601779
Zfp131 ENSMUSG00000094870 0.201075240296991 0.464329328589451 0.3095528857263 0.464329328589451 0.621633089534301 0.621633089534301

Metabolism of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Fbxo9 ENSMUSG00000001366 0.213593913192257 0.460696954000312 0.307131302666875 0.460696954000312 0.940194121838634 0.940194121838634
Mrpl10 ENSMUSG00000001445 0.135108141424782 0.202662212137173 0.00527013667070552 0.0158104100121165 0.346717541346686 0.346717541346686
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ltbp1 ENSMUSG00000001870 0.145732705713255 0.218599058569882 0.13401768964257 0.218599058569882 0.669488011967337 0.669488011967337
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Hltf ENSMUSG00000002428 0.469559400197792 0.783035674339656 0.522023782893104 0.783035674339656 0.984253887202867 0.984253887202867
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Eif2b5 ENSMUSG00000003235 0.0828391510582416 0.124258726587362 0.000894330731870369 0.00268299219561111 0.834234604248986 0.834234604248986
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Dnmt1 ENSMUSG00000004099 0.577555858074608 0.635538036514718 0.457685292289755 0.635538036514718 0.635538036514718 0.635538036514718
Etfb ENSMUSG00000004610 0.218445427241135 0.461545761682517 0.307697174455011 0.461545761682517 0.704725234059946 0.704725234059946
Eif2b2 ENSMUSG00000004788 0.865179764697839 0.865179764697839 0.319064362596573 0.481394889195354 0.320929926130236 0.481394889195354
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Ufd1l ENSMUSG00000005262 0.591252229789365 0.591252229789365 0.328797396458557 0.591252229789365 0.434033727036496 0.591252229789365
Fbxo11 ENSMUSG00000005371 0.229006001463732 0.687018004391197 0.610471723108175 0.915707584662263 0.933935404170617 0.933935404170617
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Rcn1 ENSMUSG00000005973 0.82200644313783 0.930810925390078 0.930810925390078 0.930810925390078 0.791431774351367 0.930810925390078
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Usp19 ENSMUSG00000006676 0.555985360729751 0.743015676480996 0.092602981624798 0.277808944874394 0.743015676480996 0.743015676480996
Stambp ENSMUSG00000006906 0.684279337916864 0.684279337916864 0.681389164199228 0.684279337916864 0.574989725969528 0.684279337916864
Mrpl49 ENSMUSG00000007338 0.734174282784914 0.734174282784914 0.0980688784472798 0.294206635341839 0.48939465862643 0.734091987939645
Man1a2 ENSMUSG00000008763 0.330822217752787 0.877668439988077 0.71351773942311 0.877668439988077 0.877668439988077 0.877668439988077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Pdcl ENSMUSG00000009030 0.0182323594769991 0.0273485392154987 0.0071696719873174 0.0215090159619522 0.782130256800531 0.782130256800531
Srp14 ENSMUSG00000009549 0.788379031075981 0.788379031075981 0.624388176087313 0.788379031075981 0.755166012918234 0.788379031075981
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Dhdds ENSMUSG00000012117 0.380096767525911 0.486885228563667 0.156177897574698 0.468533692724093 0.486885228563667 0.486885228563667
Rpl15 ENSMUSG00000012405 0.716465716009904 0.716465716009904 0.522265564650336 0.716465716009904 0.641299115175891 0.716465716009904
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Pigl ENSMUSG00000014245 0.713504308576772 0.977959476008201 0.977959476008201 0.977959476008201 0.602166388613618 0.977959476008201
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Mrps25 ENSMUSG00000014551 0.635644906142749 0.689988589928953 0.000876791785905 0.002630375357715 0.689988589928953 0.689988589928953
Csf1 ENSMUSG00000014599 0.574954724567226 0.574954724567226 0.494298023183587 0.574954724567226 0.408900775788184 0.574954724567226
Adamts13 ENSMUSG00000014852 0.809733209937742 0.809733209937742 0.367542031152541 0.551313046728812 0.222939063628633 0.551313046728812
Fbxw5 ENSMUSG00000015095 0.312266225489717 0.583363918635638 0.388909279090426 0.583363918635638 0.818437948865218 0.818437948865218
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Eif3d ENSMUSG00000016554 0.0980391239285879 0.147058685892882 0.00508232624133938 0.0152469787240181 0.292704381368172 0.292704381368172
Ttll12 ENSMUSG00000016757 0.521582816542189 0.782374224813284 0.045553811953198 0.136661435859594 0.921279616743216 0.921279616743216
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Top2b ENSMUSG00000017485 0.621570154742956 0.970443928900233 0.646962619266822 0.970443928900233 0.977954326966792 0.977954326966792
Wsb1 ENSMUSG00000017677 0.692964035503656 0.767165274931203 0.621531949939947 0.767165274931203 0.767165274931203 0.767165274931203
Pigt ENSMUSG00000017721 0.698534474020628 0.752174519354127 0.752174519354127 0.752174519354127 0.618477155240358 0.752174519354127
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Uchl5 ENSMUSG00000018189 0.219896114839815 0.525896260581595 0.350597507054397 0.525896260581595 0.76099969924541 0.76099969924541
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Fkbp8 ENSMUSG00000019428 0.0754988039267296 0.226496411780189 0.397661585885481 0.501093706078811 0.501093706078811 0.501093706078811
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ccdc59 ENSMUSG00000019897 0.294678256443591 0.67577941060354 0.764191064755611 0.764191064755611 0.450519607069027 0.67577941060354
Cand1 ENSMUSG00000020114 0.532628880282576 0.588494256711568 0.266363632771176 0.588494256711568 0.588494256711568 0.588494256711568
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Cpm ENSMUSG00000020183 0.179516777192962 0.538550331578887 0.971665919177245 0.971665919177245 0.624416526131332 0.936624789196999
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Pofut2 ENSMUSG00000020260 0.946504958272519 0.946504958272519 0.186082311197214 0.558246933591641 0.887002277265015 0.946504958272519
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Fstl3 ENSMUSG00000020325 0.543073977005065 0.814610965507597 0.438611788619754 0.814610965507597 0.962216658625427 0.962216658625427
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Fam20a ENSMUSG00000020614 0.363259287972013 0.544888931958019 0.328847738563471 0.544888931958019 0.797521124179864 0.797521124179864
Rnf144a ENSMUSG00000020642 0.785340357892338 0.785340357892338 0.448119551026687 0.704626611701217 0.469751074467478 0.704626611701217
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Mrpl38 ENSMUSG00000020775 0.373239265613353 0.486275077808527 0.00476404405763202 0.0142921321728961 0.486275077808527 0.486275077808527
Srp68 ENSMUSG00000020780 0.264238919134032 0.396358378701048 0.0120557124614885 0.0361671373844654 0.511534413271294 0.511534413271294
Eral1 ENSMUSG00000020832 0.0215065923475733 0.0402892213270158 0.0268594808846772 0.0402892213270158 0.168197369016707 0.168197369016707
Fbxl20 ENSMUSG00000020883 0.443360548542608 0.72231253977434 0.599400170065276 0.72231253977434 0.72231253977434 0.72231253977434
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Fut8 ENSMUSG00000021065 0.800516224830663 0.933931185203149 0.933931185203149 0.933931185203149 0.504470362618556 0.933931185203149
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Pigh ENSMUSG00000021120 0.486923236887201 0.840470186112147 0.831219976620384 0.840470186112147 0.840470186112147 0.840470186112147
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Traf3 ENSMUSG00000021277 0.996851024285757 0.996851024285757 0.50951720821185 0.996851024285757 0.974813654004815 0.996851024285757
Exoc2 ENSMUSG00000021357 0.874544623073993 0.921406376481653 0.921406376481653 0.921406376481653 0.707632544124845 0.921406376481653
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Atxn7 ENSMUSG00000021738 0.300230842914402 0.900692528743205 0.773245376445156 0.921407802086672 0.921407802086672 0.921407802086672
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ero1l ENSMUSG00000021831 0.271532657293146 0.779263764807282 0.779263764807282 0.779263764807282 0.704676658498023 0.779263764807282
Bap1 ENSMUSG00000021901 0.413407788783879 0.620111683175819 0.108343937037946 0.325031811113838 0.797530303516965 0.797530303516965
Mrp63 ENSMUSG00000021967 0.269278800696071 0.403918201044106 3.08757604467363e-09 9.26272813402089e-09 0.588137496111895 0.588137496111895
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Dcaf11 ENSMUSG00000022214 0.222574410264143 0.333861615396215 0.128980740980393 0.333861615396215 0.499343826799581 0.499343826799581
Cct5 ENSMUSG00000022234 0.862131161807723 0.862131161807723 0.417960895790413 0.862131161807723 0.652608573178535 0.862131161807723
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Josd1 ENSMUSG00000022426 0.883902927272286 0.883902927272286 0.0386462576960662 0.115938773088198 0.72239476386854 0.883902927272286
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Gpaa1 ENSMUSG00000022561 0.140166511072528 0.210249766608792 0.0554643222446901 0.16639296673407 0.41514481101606 0.41514481101606
Arsa ENSMUSG00000022620 0.388495581244411 0.743086024725586 0.743086024725586 0.743086024725586 0.604707419688747 0.743086024725586
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Senp5 ENSMUSG00000022772 0.322987682059722 0.803627553914552 0.803627553914552 0.803627553914552 0.627228423353243 0.803627553914552
B4galt4 ENSMUSG00000022793 0.556279987782527 0.846657138693467 0.803630539662222 0.846657138693467 0.846657138693467 0.846657138693467
Senp2 ENSMUSG00000022855 0.318959073507393 0.523070923993142 0.348713949328761 0.523070923993142 0.924493561362545 0.924493561362545
Eif4a2 ENSMUSG00000022884 0.776262606175218 0.794463575615136 0.509527671271441 0.794463575615136 0.794463575615136 0.794463575615136
App ENSMUSG00000022892 0.669837081661211 0.704724196773938 0.332776383296367 0.704724196773938 0.704724196773938 0.704724196773938
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Pla2g7 ENSMUSG00000023913 0.859037438093779 0.97166562509085 0.749169109814508 0.97166562509085 0.97166562509085 0.97166562509085
Satb1 ENSMUSG00000023927 0.94651011695288 0.971665729445135 0.803624675438964 0.971665729445135 0.971665729445135 0.971665729445135
Mrpl14 ENSMUSG00000023939 0.224349644592731 0.328849038970924 0.113432711288367 0.328849038970924 0.328849038970924 0.328849038970924
Spsb3 ENSMUSG00000024160 0.0132113072544738 0.0198169608817108 0.00050144460873919 0.00150433382621757 0.460065964929223 0.460065964929223
Wac ENSMUSG00000024283 0.0434174539866481 0.130252361959944 0.429356293987237 0.452649977383344 0.452649977383344 0.452649977383344
Adamts10 ENSMUSG00000024299 0.424804857545353 0.63720728631803 0.666976433193722 0.666976433193722 0.276657056968397 0.63720728631803
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Sec11c ENSMUSG00000024516 0.912011213413868 0.912011213413868 0.613299584752474 0.912011213413868 0.908883222087934 0.912011213413868
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Mrpl16 ENSMUSG00000024683 0.0994523789662465 0.14917856844937 0.000392883854206064 0.00117865156261819 0.683764418878659 0.683764418878659
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Otub1 ENSMUSG00000024767 0.2998765079153 0.2998765079153 0.185928139933512 0.2998765079153 0.250990052949487 0.2998765079153
Stambpl1 ENSMUSG00000024776 0.927676382716097 0.927676382716097 0.749167566537165 0.927676382716097 0.737218377949268 0.927676382716097
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Uhrf2 ENSMUSG00000024817 0.915142256744398 0.915142256744398 0.649828919527377 0.915142256744398 0.550973357034918 0.915142256744398
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Rce1 ENSMUSG00000024889 0.556266879142241 0.834400318713362 0.110081838544872 0.330245515634615 0.990553944009068 0.990553944009068
Smc5 ENSMUSG00000024943 0.450479271527473 0.661222470513607 0.535252137809611 0.661222470513607 0.661222470513607 0.661222470513607
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Fbxl15 ENSMUSG00000025226 0.307695222968975 0.461542834453462 0.00805888483641587 0.0241766545092476 0.859033170480059 0.859033170480059
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Mbd6 ENSMUSG00000025409 0.678201875842515 0.962204370529384 0.162065246181141 0.486195738543423 0.962204370529384 0.962204370529384
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Usp33 ENSMUSG00000025437 0.491903194177525 0.737854791266288 0.908875584338405 0.908875584338405 0.484443431720096 0.737854791266288
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumf2 ENSMUSG00000025538 0.361255356494241 0.363313512054046 0.363313512054046 0.363313512054046 0.361153066976894 0.363313512054046
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Cct8 ENSMUSG00000025613 0.646901129062633 0.924533687312387 0.924533687312387 0.924533687312387 0.737203365937647 0.924533687312387
Usp16 ENSMUSG00000025616 0.641287562523823 0.641287562523823 0.261021554656134 0.641287562523823 0.632763573931717 0.641287562523823
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Pigq ENSMUSG00000025728 0.927450586533143 0.927450586533143 0.264110142204604 0.611288452668792 0.407525635112528 0.611288452668792
Rab40c ENSMUSG00000025730 0.479507075557809 0.632857723789703 0.324918595984423 0.632857723789703 0.632857723789703 0.632857723789703
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Mettl21a ENSMUSG00000025956 0.0229191695117259 0.0451236422004621 0.0300824281336414 0.0451236422004621 0.564231120020121 0.564231120020121
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Eif5b ENSMUSG00000026083 0.106150985849222 0.318452957547666 0.675309140583142 0.782075706286792 0.782075706286792 0.782075706286792
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Asb1 ENSMUSG00000026311 0.601944165244773 0.601944165244773 0.0636532260572407 0.190959678171722 0.454867103954538 0.601944165244773
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Srp9 ENSMUSG00000026511 0.122178628505247 0.18326794275787 0.064262421146884 0.18326794275787 0.806685798790936 0.806685798790936
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Atf6 ENSMUSG00000026663 0.476925988082734 0.983161734163524 0.990553439911529 0.990553439911529 0.655441156109016 0.983161734163524
Klhl20 ENSMUSG00000026705 0.519684141499169 0.695920118882848 0.496896837138848 0.695920118882848 0.695920118882848 0.695920118882848
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Dpm2 ENSMUSG00000026810 0.324494861834532 0.50685771288579 0.50685771288579 0.50685771288579 0.365213878733351 0.50685771288579
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Dnajc24 ENSMUSG00000027166 0.420243883171676 0.630365824757515 0.36328916929203 0.630365824757515 0.87144282352072 0.87144282352072
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Mrps5 ENSMUSG00000027374 0.445764532892635 0.445764532892635 0.1435160796949 0.430548239084699 0.440819711703366 0.445764532892635
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Rab22a ENSMUSG00000027519 0.334492115394274 0.501738173091411 0.112535666740065 0.337607000220194 0.782169427079697 0.782169427079697
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Gnb4 ENSMUSG00000027669 0.896378254629603 0.896378254629603 0.719429887176208 0.896378254629603 0.58855098108693 0.896378254629603
Dcun1d1 ENSMUSG00000027708 8.10795627050442e-05 0.000243238688115133 0.0182788203713412 0.0274182305570119 0.695670533376091 0.695670533376091
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Gfm1 ENSMUSG00000027774 0.460790595428539 0.691185893142809 0.098558396456779 0.295675189370337 0.712361098875163 0.712361098875163
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Slc35a1 ENSMUSG00000028293 0.499420937815872 0.749131406723807 0.268064332008418 0.749131406723807 0.962229010589356 0.962229010589356
Rnf20 ENSMUSG00000028309 0.76415898641512 0.924530595215217 0.924530595215217 0.924530595215217 0.865241638042382 0.924530595215217
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Reck ENSMUSG00000028476 0.460074096095066 0.588529060989998 0.588529060989998 0.588529060989998 0.344799360838209 0.588529060989998
Rps6 ENSMUSG00000028495 0.332453418387945 0.367177841714712 0.0428179702760643 0.128453910828193 0.367177841714712 0.367177841714712
Usp24 ENSMUSG00000028514 0.80665519534199 0.874551056307771 0.326891407506396 0.874551056307771 0.874551056307771 0.874551056307771
Dph2 ENSMUSG00000028540 0.40659325300947 0.609889879514204 0.406532933640389 0.609889879514204 0.627198287996468 0.627198287996468
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Eif2b3 ENSMUSG00000028683 0.930808259081165 0.930808259081165 0.871435650185804 0.930808259081165 0.455204549223561 0.930808259081165
Pomgnt1 ENSMUSG00000028700 0.27138211417777 0.407073171266655 0.194158081615569 0.407073171266655 0.85278350120545 0.85278350120545
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Nub1 ENSMUSG00000028954 0.315243633036749 0.764183193354547 0.537847393351677 0.764183193354547 0.764183193354547 0.764183193354547
Park7 ENSMUSG00000028964 0.100193509532914 0.300580528598743 0.340072180267643 0.501892715742569 0.501892715742569 0.501892715742569
Pex14 ENSMUSG00000028975 0.194171505737175 0.291257258605763 0.080828462166762 0.242485386500286 0.971666162661201 0.971666162661201
Gnb1 ENSMUSG00000029064 0.752112227583879 0.752112227583879 0.424800141460724 0.752112227583879 0.635590066427997 0.752112227583879
Tada2b ENSMUSG00000029196 0.406557368296659 0.693030382940719 0.693030382940719 0.693030382940719 0.610435525360737 0.693030382940719
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Commd8 ENSMUSG00000029213 0.821925131826797 0.862093652847388 0.690103864566942 0.862093652847388 0.862093652847388 0.862093652847388
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Mrpl1 ENSMUSG00000029486 0.88699758870278 0.88699758870278 0.746159468411622 0.88699758870278 0.840478920351599 0.88699758870278
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Usp12 ENSMUSG00000029640 0.779285739065985 0.915135318836707 0.862138477061457 0.915135318836707 0.915135318836707 0.915135318836707
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Gnb2 ENSMUSG00000029713 0.014591268837441 0.0218869032561615 0.0119929612037782 0.0218869032561615 0.924500360031433 0.924500360031433
Sspo ENSMUSG00000029797 0.623658794367673 0.724206646260712 0.376101610579076 0.724206646260712 0.724206646260712 0.724206646260712
Cct7 ENSMUSG00000030007 0.311346753316152 0.467020129974228 0.222902913936356 0.467020129974228 0.55622445572701 0.55622445572701
Fbxl14 ENSMUSG00000030019 0.585733426897513 0.878600140346269 0.296343958092929 0.878600140346269 0.912009716457441 0.912009716457441
Kbtbd8 ENSMUSG00000030031 0.566939894440354 0.737225190462243 0.737225190462243 0.737225190462243 0.707644415368941 0.737225190462243
Mrpl53 ENSMUSG00000030037 0.0401931580077124 0.0602897370115686 0.00392639351352534 0.011779180540576 0.0973520328484708 0.0973520328484708
Mrpl19 ENSMUSG00000030045 0.499208617509936 0.499208617509936 0.436179481061543 0.499208617509936 0.222806286007172 0.499208617509936
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Sumf1 ENSMUSG00000030101 0.837371323658567 0.837371323658567 0.580355798372116 0.837371323658567 0.50951488825813 0.837371323658567
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Rad18 ENSMUSG00000030254 0.274811771450367 0.577392108098863 0.450487835959263 0.577392108098863 0.577392108098863 0.577392108098863
Ttll3 ENSMUSG00000030276 0.239995701502962 0.6828364895035 0.818901488714662 0.818901488714662 0.455224326335667 0.6828364895035
Mrpl51 ENSMUSG00000030335 0.852825051723097 0.981109194516913 0.610489199786653 0.981109194516913 0.981109194516913 0.981109194516913
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Prmt3 ENSMUSG00000030505 0.593991322486657 0.890986983729985 0.178245336869303 0.534736010607908 0.918269479210841 0.918269479210841
Asb7 ENSMUSG00000030509 0.886996648412827 0.886996648412827 0.722376332987625 0.886996648412827 0.855908935982981 0.886996648412827
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Mfge8 ENSMUSG00000030605 0.198245467661143 0.297368201491715 0.0843686667435072 0.253106000230521 0.413374383737894 0.413374383737894
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Eif3c ENSMUSG00000030738 0.545414817842599 0.818122226763899 0.821959523795508 0.821959523795508 0.390875201608029 0.818122226763899
Fbxl19 ENSMUSG00000030811 0.859032111304213 0.859032111304213 0.624401770964706 0.859032111304213 0.821993934939889 0.859032111304213
Rnf40 ENSMUSG00000030816 0.322848210432661 0.603267145078526 0.402178096719017 0.603267145078526 0.930785590716957 0.930785590716957
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Mettl10 ENSMUSG00000030960 0.752156340150425 0.794463687823316 0.350889481311581 0.794463687823316 0.794463687823316 0.794463687823316
Atp6ap2 ENSMUSG00000031007 0.94336470935229 0.94336470935229 0.672712877948137 0.94336470935229 0.70764796711393 0.94336470935229
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Ccdc22 ENSMUSG00000031143 0.607550712820628 0.607550712820628 0.215418375774768 0.607550712820628 0.599239281039663 0.607550712820628
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Chrdl1 ENSMUSG00000031283 0.655453404014524 0.915114154789103 0.535203850136679 0.915114154789103 0.915114154789103 0.915114154789103
Glt28d2 ENSMUSG00000031286 0.831144980850077 0.949621753864074 0.949621753864074 0.949621753864074 0.678099586980704 0.949621753864074
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Mrps31 ENSMUSG00000031533 0.169359685159387 0.508079055478161 0.367485220111959 0.551227830167938 0.632834848635877 0.632834848635877
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Amfr ENSMUSG00000031751 0.160598941935287 0.24089841290293 0.00166099377824492 0.00498298133473477 0.98739575239825 0.98739575239825
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Usp10 ENSMUSG00000031826 0.431196316155006 0.704660933121012 0.704660933121012 0.704660933121012 0.658011866762809 0.704660933121012
Mbtps1 ENSMUSG00000031835 0.126737032857096 0.380211098571289 0.417920674420203 0.626881011630305 0.722195456436019 0.722195456436019
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Nae1 ENSMUSG00000031878 0.825080834674905 0.834312035461909 0.386783536357782 0.834312035461909 0.834312035461909 0.834312035461909
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Alg9 ENSMUSG00000032059 0.865216430727327 0.865216430727327 0.0872328677294176 0.261698603188253 0.728305688303467 0.865216430727327
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Commd4 ENSMUSG00000032299 0.0734255678782446 0.220276703634734 0.411089384112583 0.596699420845023 0.596699420845023 0.596699420845023
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Gnai2 ENSMUSG00000032562 0.764147302047563 0.828140918654959 0.302010370080407 0.828140918654959 0.828140918654959 0.828140918654959
Mrpl3 ENSMUSG00000032563 0.298371288975307 0.44755693346296 0.025490576628576 0.0764717298857281 0.635671825970454 0.635671825970454
Usp4 ENSMUSG00000032612 0.476276255657081 0.669269987649272 0.213927345158588 0.641782035475763 0.669269987649272 0.669269987649272
Sbspon ENSMUSG00000032719 0.638684234808694 0.848784859375415 0.0553413172599474 0.166023951779842 0.848784859375415 0.848784859375415
Folr2 ENSMUSG00000032725 0.352129641827052 0.579309440947877 0.386206293965251 0.579309440947877 0.815833467125827 0.815833467125827
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Ttll4 ENSMUSG00000033257 0.725349744051266 0.899502702700766 0.855937088886064 0.899502702700766 0.899502702700766 0.899502702700766
Fem1c ENSMUSG00000033319 0.908878957745757 0.908878957745757 0.266370389855722 0.799111169567166 0.728297759692514 0.908878957745757
Usp37 ENSMUSG00000033364 0.157368156181812 0.472104468545437 0.940226488909329 0.940226488909329 0.834308461857482 0.940226488909329
Fuk ENSMUSG00000033703 0.202504121652905 0.303756182479357 0.110117431939355 0.303756182479357 0.831224840369681 0.831224840369681
Gadd45gip1 ENSMUSG00000033751 0.350919208285921 0.526378812428882 0.000331012699510938 0.000993038098532814 0.770215279366041 0.770215279366041
Alg3 ENSMUSG00000033809 0.0337267523379115 0.0545486602768248 0.0363657735178832 0.0545486602768248 0.454677354933429 0.454677354933429
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Tpst1 ENSMUSG00000034118 0.225838125044132 0.338757187566199 0.159632371164343 0.338757187566199 0.486888786106925 0.486888786106925
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Nagk ENSMUSG00000034744 0.132873937161566 0.398621811484697 0.58561417216832 0.644087090424569 0.644087090424569 0.644087090424569
Rab24 ENSMUSG00000034789 0.548039956007639 0.822059934011459 0.402099592875922 0.822059934011459 0.946462875743045 0.946462875743045
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
Eif2s3x ENSMUSG00000035150 0.195519148289058 0.376945323539439 0.251296882359626 0.376945323539439 0.915138462344492 0.915138462344492
Spcs2 ENSMUSG00000035227 0.561227043196396 0.949622940449274 0.719332526599661 0.949622940449274 0.949622940449274 0.949622940449274
Ntng2 ENSMUSG00000035513 0.937054446139716 0.937054446139716 0.704594261107055 0.937054446139716 0.743058341350706 0.937054446139716
Mrps2 ENSMUSG00000035772 0.571780579335521 0.69548353245222 0.00177627013660683 0.00532881040982049 0.69548353245222 0.69548353245222
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Adamtsl2 ENSMUSG00000036040 0.818933743512121 0.818933743512121 0.151599816859915 0.454799450579745 0.621645127359781 0.818933743512121
Mgat5 ENSMUSG00000036155 0.61329363619444 0.927676688706274 0.927676688706274 0.927676688706274 0.773241361632843 0.927676688706274
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Exoc1 ENSMUSG00000036435 0.415543130583432 0.770095312459101 0.770095312459101 0.770095312459101 0.56159350154872 0.770095312459101
Cyld ENSMUSG00000036712 0.893249471687713 0.98110763185907 0.773243036549786 0.98110763185907 0.98110763185907 0.98110763185907
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Inhbb ENSMUSG00000037035 0.616073058282604 0.616073058282604 0.532608214466361 0.616073058282604 0.524875068365983 0.616073058282604
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Mrps26 ENSMUSG00000037740 0.146765706734631 0.220148560101947 0.122149021366324 0.220148560101947 0.76689684158726 0.76689684158726
Satb2 ENSMUSG00000038331 0.701180780170431 0.949531112457672 0.949531112457672 0.949531112457672 0.727458227478397 0.949531112457672
Pigu ENSMUSG00000038383 0.176926134305675 0.530778402917025 0.883880384398204 0.883880384398204 0.610420955622581 0.883880384398204
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Otud7b ENSMUSG00000038495 0.655377085525873 0.849652001261297 0.669727460305022 0.849652001261297 0.849652001261297 0.849652001261297
Gng10 ENSMUSG00000038607 0.779298584363925 0.89325835750727 0.89325835750727 0.89325835750727 0.369641003660815 0.89325835750727
Josd2 ENSMUSG00000038695 0.320854786789104 0.320854786789104 0.012772647551706 0.038317942655118 0.221300509313193 0.320854786789104
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Mrps34 ENSMUSG00000038880 0.010542744418389 0.0158141166275835 3.70455048229177e-08 1.11136514468753e-07 0.632704774407266 0.632704774407266
Adrm1 ENSMUSG00000039041 0.104965021816539 0.157447532724809 0.0397463098480413 0.119238929544124 0.571749204282725 0.571749204282725
Pigk ENSMUSG00000039047 0.758182007536299 0.758182007536299 0.62163877745223 0.758182007536299 0.719426675472166 0.758182007536299
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Fn3krp ENSMUSG00000039253 0.556039744282312 0.643957639015951 0.186075932013599 0.558227796040798 0.643957639015951 0.643957639015951
Foxk2 ENSMUSG00000039275 0.49692369178867 0.815866894959488 0.815866894959488 0.815866894959488 0.800575809275715 0.815866894959488
Alg1 ENSMUSG00000039427 0.238169764923128 0.238169764923128 0.0288573539356085 0.0865720618068256 0.213940154501969 0.238169764923128
Asb6 ENSMUSG00000039483 0.918255734950225 0.918255734950225 0.862104557997622 0.918255734950225 0.692981424119149 0.918255734950225
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mrpl12 ENSMUSG00000039640 0.710548359219292 0.825055599680069 0.649696762265791 0.825055599680069 0.825055599680069 0.825055599680069
Fbxl5 ENSMUSG00000039753 0.460089905660059 0.527349966742554 0.382374381325839 0.527349966742554 0.527349966742554 0.527349966742554
Spsb1 ENSMUSG00000039911 0.319080089631295 0.580187025826347 0.865240833296443 0.865240833296443 0.386791350550898 0.580187025826347
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Klhl42 ENSMUSG00000040102 0.472026108099081 0.868301215980349 0.868301215980349 0.868301215980349 0.776168664106968 0.868301215980349
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Mrps28 ENSMUSG00000040269 0.638344797990741 0.80350624757688 0.737134096456746 0.80350624757688 0.80350624757688 0.80350624757688
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Manea ENSMUSG00000040520 0.328803574646066 0.455025853771683 0.316806879814107 0.455025853771683 0.455025853771683 0.455025853771683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
St8sia4 ENSMUSG00000040710 0.818878583905477 0.965369500416752 0.965369500416752 0.965369500416752 0.585685930180055 0.965369500416752
Eif4h ENSMUSG00000040731 0.15851464980349 0.237771974705236 0.0192929694775784 0.0578789084327351 0.66983971928632 0.66983971928632
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Fbxw4 ENSMUSG00000040913 0.0822124854277177 0.224008023834634 0.149338682556422 0.224008023834634 0.707633447761154 0.707633447761154
Ccdc8 ENSMUSG00000041117 0.722333779317285 0.722333779317285 0.522286127004673 0.722333779317285 0.537725250716463 0.722333779317285
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Pigs ENSMUSG00000041958 0.420220167764266 0.630330251646399 0.141622561647642 0.424867684942927 0.984256431021961 0.984256431021961
Mat2b ENSMUSG00000042032 0.42020009065683 0.630300135985245 0.908878380342246 0.908878380342246 0.411153687199577 0.630300135985245
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Asxl1 ENSMUSG00000042548 0.408861338264557 0.930794506513674 0.710447901186555 0.930794506513674 0.930794506513674 0.930794506513674
Commd10 ENSMUSG00000042705 0.333975226661427 0.797307701580356 0.797307701580356 0.797307701580356 0.577357289469794 0.797307701580356
Gng2 ENSMUSG00000043004 0.803607853159088 0.803607853159088 0.746086303777471 0.803607853159088 0.30193486428631 0.803607853159088
Usp48 ENSMUSG00000043411 0.675576381154849 0.779281728953017 0.459996534139036 0.779281728953017 0.779281728953017 0.779281728953017
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
N6amt1 ENSMUSG00000044442 0.415677866924896 0.455272347645021 0.0857665148196928 0.257299544459078 0.455272347645021 0.455272347645021
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Adamts6 ENSMUSG00000046169 0.9779273142477 0.9779273142477 0.338466900336666 0.513582561214954 0.342388374143303 0.513582561214954
Rpl27a ENSMUSG00000046364 0.486953491393843 0.915127538804999 0.74616335633815 0.915127538804999 0.915127538804999 0.915127538804999
Yod1 ENSMUSG00000046404 0.159663361778729 0.477072661212058 0.477072661212058 0.477072661212058 0.388914696094678 0.477072661212058
B3gntl1 ENSMUSG00000046605 0.100606323949638 0.301818971848914 0.921403183894556 0.921403183894556 0.386599473615831 0.579899210423747
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Mrps7 ENSMUSG00000046756 0.249630745509719 0.249630745509719 0.000418909211856353 0.00125672763556906 0.126071691204319 0.189107536806478
Ckap4 ENSMUSG00000046841 0.646976442792832 0.79143832733529 0.321052539934727 0.79143832733529 0.79143832733529 0.79143832733529
Mbtps2 ENSMUSG00000046873 0.120181267672012 0.360543803016036 0.309502130103456 0.464253195155184 0.868285830636168 0.868285830636168
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Crebrf ENSMUSG00000048249 0.519683721220091 0.779525581830136 0.328698794580104 0.779525581830136 0.785278887926031 0.785278887926031
Dcun1d3 ENSMUSG00000048787 0.0446830301930137 0.134049090579041 0.522239834738647 0.783359752107971 0.94336638862497 0.94336638862497
Tada3 ENSMUSG00000048930 0.445386787053696 0.668080180580543 0.127981844316683 0.383945532950048 0.893137831012048 0.893137831012048
Dcaf7 ENSMUSG00000049354 0.779251754242924 0.890124914594691 0.298363761411075 0.890124914594691 0.890124914594691 0.890124914594691
Mettl21d ENSMUSG00000049882 0.457460368111691 0.692903445365971 0.692903445365971 0.692903445365971 0.583029679454939 0.692903445365971
Usp42 ENSMUSG00000051306 0.517173520468805 0.852835531331225 0.669841315712961 0.852835531331225 0.852835531331225 0.852835531331225
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
B3galtl ENSMUSG00000051950 0.905749343806834 0.908883677861065 0.908883677861065 0.908883677861065 0.887014572566288 0.908883677861065
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
B4galt3 ENSMUSG00000052423 0.555852678813415 0.833779018220122 0.981105507625407 0.981105507625407 0.481717689407786 0.833779018220122
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
St6galnac3 ENSMUSG00000052544 0.457673821176896 0.686510731765344 0.927671188342965 0.927671188342965 0.246407613661978 0.686510731765344
Gan ENSMUSG00000052557 0.313344114171842 0.470016171257763 0.26299500485965 0.470016171257763 0.681391720765928 0.681391720765928
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435
Rab4b ENSMUSG00000053291 0.484474264461291 0.613292882690895 0.613292882690895 0.613292882690895 0.496911756913925 0.613292882690895
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ubxn7 ENSMUSG00000053774 0.378158472049596 0.708274209461876 0.472182806307917 0.708274209461876 0.943363017302423 0.943363017302423
Fpgt ENSMUSG00000053870 0.290907432114314 0.50798959574374 0.338659730495827 0.50798959574374 0.755157091765088 0.755157091765088
Nanp ENSMUSG00000053916 0.874426704515627 0.987391425325871 0.987391425325871 0.987391425325871 0.286465426520232 0.859396279560696
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mrps21 ENSMUSG00000054312 0.896349781040251 0.896349781040251 0.87767571705924 0.896349781040251 0.855908458403065 0.896349781040251
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Adam10 ENSMUSG00000054693 0.613194850137555 0.613194850137555 0.388947779275199 0.613194850137555 0.530026456466922 0.613194850137555
Klhl5 ENSMUSG00000054920 0.441023563137958 0.556142046462253 0.540328093857368 0.556142046462253 0.556142046462253 0.556142046462253
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Ddx17 ENSMUSG00000055065 0.828152914507463 0.871447107023116 0.871447107023116 0.871447107023116 0.489429050732231 0.871447107023116
Fbxo6 ENSMUSG00000055401 0.165725488149896 0.344494721839957 0.307467389409342 0.344494721839957 0.344494721839957 0.344494721839957
Klhl25 ENSMUSG00000055652 0.0531566348600952 0.159469904580285 0.219797201332521 0.329695801998782 0.342050703942181 0.342050703942181
Gpc3 ENSMUSG00000055653 0.933951116944975 0.933951116944975 0.41796334423776 0.933951116944975 0.818935174009707 0.933951116944975
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Socs6 ENSMUSG00000056153 0.420212053945563 0.803600482650626 0.585800975843989 0.803600482650626 0.803600482650626 0.803600482650626
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Foxk1 ENSMUSG00000056493 0.90262961659103 0.971667329399804 0.971667329399804 0.971667329399804 0.912012543977666 0.971667329399804
Apol8 ENSMUSG00000056656 0.784633163944802 0.803972950501445 0.625700232844416 0.803972950501445 0.803972950501445 0.803972950501445
Commd7 ENSMUSG00000056941 0.652676785235519 0.987405591197671 0.987405591197671 0.987405591197671 0.740221145448748 0.987405591197671
Ces1d ENSMUSG00000056973 0.880789432238333 0.981108895090248 0.981108895090248 0.981108895090248 0.962228820975014 0.981108895090248
Dph6 ENSMUSG00000057147 0.208146752517076 0.312220128775613 0.0981750414524178 0.294525124357253 0.821996651788269 0.821996651788269
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Mrpl18 ENSMUSG00000057388 0.585541873356049 0.886994930755914 0.722190273128618 0.886994930755914 0.886994930755914 0.886994930755914
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Rpl5 ENSMUSG00000058558 0.883851475294508 0.883851475294508 0.346774973373787 0.883851475294508 0.791411246773245 0.883851475294508
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Nsmce2 ENSMUSG00000059586 0.424673594011485 0.655411431505958 0.556173761323834 0.655411431505958 0.655411431505958 0.655411431505958
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Rpl3 ENSMUSG00000060036 0.604814804072583 0.837312671662592 0.837312671662592 0.837312671662592 0.588539563068734 0.837312671662592
Dhps ENSMUSG00000060038 0.151546602836817 0.45463980851045 0.334760175682778 0.502140263524168 0.644125113609677 0.644125113609677
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Exoc5 ENSMUSG00000061244 0.108322260304065 0.324966780912195 0.355026060691986 0.532539091037979 0.921401924246316 0.921401924246316
Mysm1 ENSMUSG00000062627 0.402165611878691 0.603248417818037 0.233701829303918 0.603248417818037 0.675609193134516 0.675609193134516
Mrpl42 ENSMUSG00000062981 0.194057283561426 0.444565507023462 0.296377004682308 0.444565507023462 0.734213636229113 0.734213636229113
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Gng8 ENSMUSG00000063594 0.644090126802365 0.649764722457812 0.649764722457812 0.649764722457812 0.455188806742285 0.649764722457812
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Fbxl12 ENSMUSG00000066892 0.514569590928347 0.771854386392521 0.968518283937401 0.968518283937401 0.404276434285822 0.771854386392521
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Tcp1 ENSMUSG00000068039 0.971656190495982 0.971656190495982 0.849725921700933 0.971656190495982 0.92451559146861 0.971656190495982
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Dap3 ENSMUSG00000068921 0.102278817972956 0.306836453918868 0.309583355757949 0.464375033636923 0.63285373424436 0.63285373424436
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
B3gnt9 ENSMUSG00000069920 0.556264495629011 0.710538444756707 0.710538444756707 0.710538444756707 0.241580920278622 0.710538444756707
Eif3g ENSMUSG00000070319 0.146988948050685 0.220483422076027 0.0630237512779181 0.189071253833754 0.749115647096656 0.749115647096656
Ndnl2 ENSMUSG00000070520 0.655479660571186 0.776254822726478 0.190002999328858 0.570008997986575 0.776254822726478 0.776254822726478
Top1 ENSMUSG00000070544 0.0524875749189175 0.157462724756753 0.865185136694549 0.981099842312976 0.981099842312976 0.981099842312976
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Camkmt ENSMUSG00000071037 0.51204997609742 0.76807496414613 0.489425553543675 0.76807496414613 0.990552829191558 0.990552829191558
Safb ENSMUSG00000071054 0.574823745567258 0.883875670750215 0.825027507382374 0.883875670750215 0.883875670750215 0.883875670750215
Eef1g ENSMUSG00000071644 0.228972452774007 0.343458679161011 0.0382268940582917 0.114680682174875 0.828134853653921 0.828134853653921
Srp54a ENSMUSG00000073079 4.91647294322341e-05 0.000147494188296702 0.000926217431796866 0.0013893261476953 0.580284548238714 0.580284548238714
Pgap1 ENSMUSG00000073678 0.434024879763406 0.818907750235861 0.553616938893275 0.818907750235861 0.818907750235861 0.818907750235861
Rpl31 ENSMUSG00000073702 0.852839186481883 0.852839186481883 0.773231680871232 0.852839186481883 0.624431821651762 0.852839186481883
Alg6 ENSMUSG00000073792 0.968509806380037 0.968509806380037 0.902606179045671 0.968509806380037 0.548297525238618 0.968509806380037
Exoc8 ENSMUSG00000074030 0.849737247415159 0.984252197087892 0.183285563776723 0.54985669133017 0.984252197087892 0.984252197087892
Dda1 ENSMUSG00000074247 0.758049932577639 0.959057354226814 0.616040528394896 0.959057354226814 0.959057354226814 0.959057354226814
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Dolk ENSMUSG00000075419 0.0148011689873284 0.0148011689873284 2.65654703682613e-05 7.96964111047838e-05 0.0119531327006982 0.0148011689873284
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Dph1 ENSMUSG00000078789 0.0998175001638427 0.256261059321669 0.232132913023625 0.256261059321669 0.256261059321669 0.256261059321669
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074
Dpm1 ENSMUSG00000078919 0.0409862603823654 0.0614793905735481 0.0180882720006123 0.0542648160018368 0.937087214004604 0.937087214004604
Pigb ENSMUSG00000079469 0.937071267899132 0.937071267899132 0.424778166119504 0.654357997262867 0.436238664841912 0.654357997262867
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Shprh ENSMUSG00000090112 0.561578278019075 0.561578278019075 0.378124993618767 0.561578278019075 0.330806941366433 0.561578278019075
Fbxw10 ENSMUSG00000090173 0.74415417304833 0.74415417304833 0.635518344743522 0.74415417304833 0.729025476397157 0.74415417304833
Rps13 ENSMUSG00000090862 0.29630077432146 0.40846885160083 0.0136541774831532 0.0409625324494596 0.40846885160083 0.40846885160083
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298
Gm20716 ENSMUSG00000093752 0.83425163601779 0.83425163601779 0.545583608319016 0.83425163601779 0.7431635404496 0.83425163601779
Zfp131 ENSMUSG00000094870 0.201075240296991 0.464329328589451 0.3095528857263 0.464329328589451 0.621633089534301 0.621633089534301

SUMOylation of DNA damage response and repair proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Smc5 ENSMUSG00000024943 0.450479271527473 0.661222470513607 0.535252137809611 0.661222470513607 0.661222470513607 0.661222470513607
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nsmce2 ENSMUSG00000059586 0.424673594011485 0.655411431505958 0.556173761323834 0.655411431505958 0.655411431505958 0.655411431505958
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Ndnl2 ENSMUSG00000070520 0.655479660571186 0.776254822726478 0.190002999328858 0.570008997986575 0.776254822726478 0.776254822726478

Transport of Mature Transcript to Cytoplasm

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

RNA Polymerase II Pre-transcription Events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Supt6 ENSMUSG00000002052 0.918249683822428 0.921384615446289 0.509525588181232 0.921384615446289 0.921384615446289 0.921384615446289
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Mllt1 ENSMUSG00000024212 0.974811565183814 0.974811565183814 0.543035961218538 0.974811565183814 0.837368583319366 0.974811565183814
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Iws1 ENSMUSG00000024384 0.613303748580275 0.613303748580275 0.469731250453748 0.613303748580275 0.59672817939277 0.613303748580275
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Chromatin organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.127086859667951 0.190630289501926 0.0880298593793974 0.190630289501926 0.455295294594226 0.455295294594226
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Kansl3 ENSMUSG00000010453 0.433472716159515 0.650209074239273 0.399613773126658 0.650209074239273 0.843246126167187 0.843246126167187
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Kansl1 ENSMUSG00000018412 0.940158621019912 0.940158621019912 0.73710508827901 0.940158621019912 0.905618365246514 0.940158621019912
Kdm6b ENSMUSG00000018476 0.484195545231719 0.626973949023456 0.413265451928212 0.626973949023456 0.626973949023456 0.626973949023456
Phf15 ENSMUSG00000020387 0.687207567008137 0.971664318983643 0.800565431638619 0.971664318983643 0.971664318983643 0.971664318983643
Dnmt3a ENSMUSG00000020661 0.695929769387012 0.871446110897976 0.86214080855387 0.871446110897976 0.871446110897976 0.871446110897976
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Brwd1 ENSMUSG00000022914 0.971650586025817 0.990553379794094 0.990553379794094 0.990553379794094 0.902569105401371 0.990553379794094
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Gps2 ENSMUSG00000023170 0.542865789388673 0.949603579078036 0.678375173642524 0.949603579078036 0.949603579078036 0.949603579078036
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Tbl1x ENSMUSG00000025246 0.949633171970116 0.990551854325694 0.782226920895053 0.990551854325694 0.990551854325694 0.990551854325694
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Phf17 ENSMUSG00000025764 0.569608440790859 0.993697933969124 0.754972626572436 0.993697933969124 0.993697933969124 0.993697933969124
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Tbl1xr1 ENSMUSG00000027630 0.486940143036373 0.730410214554559 0.380216907855341 0.730410214554559 0.971661244333188 0.971661244333188
Ash1l ENSMUSG00000028053 0.378153132937169 0.722398003757208 0.594008023836612 0.722398003757208 0.722398003757208 0.722398003757208
Kdm4c ENSMUSG00000028397 0.752172993418601 0.752172993418601 0.63847792114878 0.752172993418601 0.604983323017792 0.752172993418601
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Kdm2b ENSMUSG00000029475 0.199641186136049 0.566928971762651 0.445675590919164 0.566928971762651 0.566928971762651 0.566928971762651
Kdm5a ENSMUSG00000030180 0.152740628056526 0.407308902744028 0.271539268496019 0.407308902744028 0.707645381207135 0.707645381207135
Atf7ip ENSMUSG00000030213 0.749177881586968 0.984256550535308 0.984256550535308 0.984256550535308 0.675607826167175 0.984256550535308
Aebp2 ENSMUSG00000030232 0.977953534107396 0.981104927397305 0.399951668653518 0.981104927397305 0.981104927397305 0.981104927397305
Ing4 ENSMUSG00000030330 0.0672153039305514 0.201645911791654 0.618810953285995 0.618810953285995 0.462454587822382 0.618810953285995
Prmt3 ENSMUSG00000030505 0.593991322486657 0.890986983729985 0.178245336869303 0.534736010607908 0.918269479210841 0.918269479210841
Kat8 ENSMUSG00000030801 0.48694145843119 0.535227995840665 0.535227995840665 0.535227995840665 0.408905600063383 0.535227995840665
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Setd6 ENSMUSG00000031671 0.218104872596431 0.654314617789292 0.862117320600689 0.862117320600689 0.681322032333544 0.862117320600689
Carm1 ENSMUSG00000032185 0.672407698617612 0.990552795435014 0.990552795435014 0.990552795435014 0.7340345327491 0.990552795435014
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Kdm1a ENSMUSG00000036940 0.561448376444258 0.842172564666387 0.450458492275885 0.842172564666387 0.968508927302806 0.968508927302806
Phf16 ENSMUSG00000037315 0.198250003984015 0.594750011952045 0.731085974365816 0.788262803090994 0.788262803090994 0.788262803090994
Kdm6a ENSMUSG00000037369 0.692949249602849 0.692949249602849 0.64126672766829 0.692949249602849 0.564225545061856 0.692949249602849
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Phf2 ENSMUSG00000038025 0.852822110531568 0.952790100232227 0.952790100232227 0.952790100232227 0.675588891894769 0.952790100232227
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Kat7 ENSMUSG00000038909 0.678512363150713 0.678512363150713 0.438688497868846 0.658032746803269 0.328828069028127 0.658032746803269
Arid4b ENSMUSG00000039219 0.616049913620673 0.831215855099151 0.438735317877883 0.831215855099151 0.831215855099151 0.831215855099151
Suv39h1 ENSMUSG00000039231 0.300114033243424 0.523179722078619 0.348786481385746 0.523179722078619 0.63563708959381 0.63563708959381
Phf8 ENSMUSG00000041229 0.655503966856237 0.927672726638313 0.746183422865989 0.927672726638313 0.927672726638313 0.927672726638313
Kdm5b ENSMUSG00000042207 0.797529374580581 0.905741884779121 0.43164088085525 0.905741884779121 0.905741884779121 0.905741884779121
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Jhdm1d ENSMUSG00000042599 0.402192213680522 0.85903363775593 0.646986037425943 0.85903363775593 0.85903363775593 0.85903363775593
Setd2 ENSMUSG00000044791 0.467313888562916 0.877651292404873 0.806647171702163 0.877651292404873 0.877651292404873 0.877651292404873
Suv420h1 ENSMUSG00000045098 0.352900406954565 0.616037846775787 0.591252934622595 0.616037846775787 0.616037846775787 0.616037846775787
Arid4a ENSMUSG00000048118 0.287450573738789 0.862351721216368 0.583112554364735 0.874668831547103 0.98425726228637 0.98425726228637
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Prmt6 ENSMUSG00000049300 0.965374627946491 0.981108445923553 0.616073215983192 0.981108445923553 0.981108445923553 0.981108445923553
Msl1 ENSMUSG00000052915 0.593924867895851 0.776217548211989 0.472039200468143 0.776217548211989 0.776217548211989 0.776217548211989
Kdm3a ENSMUSG00000053470 0.438693620968127 0.990549673500904 0.990549673500904 0.990549673500904 0.710438842159779 0.990549673500904
Whsc1l1 ENSMUSG00000054823 0.42248651259866 0.927659144367208 0.927659144367208 0.927659144367208 0.834289240651817 0.927659144367208
Smyd3 ENSMUSG00000055067 0.44579048970704 0.655523192190828 0.655523192190828 0.655523192190828 0.464914868467631 0.655523192190828
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Jmjd6 ENSMUSG00000056962 0.420034402732909 0.630051604099364 0.103931571214 0.311794713641999 0.855927780679312 0.855927780679312
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Suv420h2 ENSMUSG00000059851 0.837383680330376 0.837383680330376 0.828142751254817 0.837383680330376 0.524887626690907 0.837383680330376
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Prmt7 ENSMUSG00000060098 0.269662556245471 0.287176433111421 0.0271449951104654 0.0814349853313963 0.287176433111421 0.287176433111421
Dot1l ENSMUSG00000061589 0.504435806113353 0.713518810138284 0.713518810138284 0.713518810138284 0.494387660202947 0.713518810138284
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Msl2 ENSMUSG00000066415 0.924536064943825 0.971666760277029 0.561590614448763 0.971666760277029 0.971666760277029 0.971666760277029
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Chromatin modifying enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.127086859667951 0.190630289501926 0.0880298593793974 0.190630289501926 0.455295294594226 0.455295294594226
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Kansl3 ENSMUSG00000010453 0.433472716159515 0.650209074239273 0.399613773126658 0.650209074239273 0.843246126167187 0.843246126167187
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Kansl1 ENSMUSG00000018412 0.940158621019912 0.940158621019912 0.73710508827901 0.940158621019912 0.905618365246514 0.940158621019912
Kdm6b ENSMUSG00000018476 0.484195545231719 0.626973949023456 0.413265451928212 0.626973949023456 0.626973949023456 0.626973949023456
Phf15 ENSMUSG00000020387 0.687207567008137 0.971664318983643 0.800565431638619 0.971664318983643 0.971664318983643 0.971664318983643
Dnmt3a ENSMUSG00000020661 0.695929769387012 0.871446110897976 0.86214080855387 0.871446110897976 0.871446110897976 0.871446110897976
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Brwd1 ENSMUSG00000022914 0.971650586025817 0.990553379794094 0.990553379794094 0.990553379794094 0.902569105401371 0.990553379794094
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Gps2 ENSMUSG00000023170 0.542865789388673 0.949603579078036 0.678375173642524 0.949603579078036 0.949603579078036 0.949603579078036
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Tbl1x ENSMUSG00000025246 0.949633171970116 0.990551854325694 0.782226920895053 0.990551854325694 0.990551854325694 0.990551854325694
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Phf17 ENSMUSG00000025764 0.569608440790859 0.993697933969124 0.754972626572436 0.993697933969124 0.993697933969124 0.993697933969124
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Tbl1xr1 ENSMUSG00000027630 0.486940143036373 0.730410214554559 0.380216907855341 0.730410214554559 0.971661244333188 0.971661244333188
Ash1l ENSMUSG00000028053 0.378153132937169 0.722398003757208 0.594008023836612 0.722398003757208 0.722398003757208 0.722398003757208
Kdm4c ENSMUSG00000028397 0.752172993418601 0.752172993418601 0.63847792114878 0.752172993418601 0.604983323017792 0.752172993418601
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Kdm2b ENSMUSG00000029475 0.199641186136049 0.566928971762651 0.445675590919164 0.566928971762651 0.566928971762651 0.566928971762651
Kdm5a ENSMUSG00000030180 0.152740628056526 0.407308902744028 0.271539268496019 0.407308902744028 0.707645381207135 0.707645381207135
Atf7ip ENSMUSG00000030213 0.749177881586968 0.984256550535308 0.984256550535308 0.984256550535308 0.675607826167175 0.984256550535308
Aebp2 ENSMUSG00000030232 0.977953534107396 0.981104927397305 0.399951668653518 0.981104927397305 0.981104927397305 0.981104927397305
Ing4 ENSMUSG00000030330 0.0672153039305514 0.201645911791654 0.618810953285995 0.618810953285995 0.462454587822382 0.618810953285995
Prmt3 ENSMUSG00000030505 0.593991322486657 0.890986983729985 0.178245336869303 0.534736010607908 0.918269479210841 0.918269479210841
Kat8 ENSMUSG00000030801 0.48694145843119 0.535227995840665 0.535227995840665 0.535227995840665 0.408905600063383 0.535227995840665
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Setd6 ENSMUSG00000031671 0.218104872596431 0.654314617789292 0.862117320600689 0.862117320600689 0.681322032333544 0.862117320600689
Carm1 ENSMUSG00000032185 0.672407698617612 0.990552795435014 0.990552795435014 0.990552795435014 0.7340345327491 0.990552795435014
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Kdm1a ENSMUSG00000036940 0.561448376444258 0.842172564666387 0.450458492275885 0.842172564666387 0.968508927302806 0.968508927302806
Phf16 ENSMUSG00000037315 0.198250003984015 0.594750011952045 0.731085974365816 0.788262803090994 0.788262803090994 0.788262803090994
Kdm6a ENSMUSG00000037369 0.692949249602849 0.692949249602849 0.64126672766829 0.692949249602849 0.564225545061856 0.692949249602849
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Phf2 ENSMUSG00000038025 0.852822110531568 0.952790100232227 0.952790100232227 0.952790100232227 0.675588891894769 0.952790100232227
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Kat7 ENSMUSG00000038909 0.678512363150713 0.678512363150713 0.438688497868846 0.658032746803269 0.328828069028127 0.658032746803269
Arid4b ENSMUSG00000039219 0.616049913620673 0.831215855099151 0.438735317877883 0.831215855099151 0.831215855099151 0.831215855099151
Suv39h1 ENSMUSG00000039231 0.300114033243424 0.523179722078619 0.348786481385746 0.523179722078619 0.63563708959381 0.63563708959381
Phf8 ENSMUSG00000041229 0.655503966856237 0.927672726638313 0.746183422865989 0.927672726638313 0.927672726638313 0.927672726638313
Kdm5b ENSMUSG00000042207 0.797529374580581 0.905741884779121 0.43164088085525 0.905741884779121 0.905741884779121 0.905741884779121
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Jhdm1d ENSMUSG00000042599 0.402192213680522 0.85903363775593 0.646986037425943 0.85903363775593 0.85903363775593 0.85903363775593
Setd2 ENSMUSG00000044791 0.467313888562916 0.877651292404873 0.806647171702163 0.877651292404873 0.877651292404873 0.877651292404873
Suv420h1 ENSMUSG00000045098 0.352900406954565 0.616037846775787 0.591252934622595 0.616037846775787 0.616037846775787 0.616037846775787
Arid4a ENSMUSG00000048118 0.287450573738789 0.862351721216368 0.583112554364735 0.874668831547103 0.98425726228637 0.98425726228637
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Prmt6 ENSMUSG00000049300 0.965374627946491 0.981108445923553 0.616073215983192 0.981108445923553 0.981108445923553 0.981108445923553
Msl1 ENSMUSG00000052915 0.593924867895851 0.776217548211989 0.472039200468143 0.776217548211989 0.776217548211989 0.776217548211989
Kdm3a ENSMUSG00000053470 0.438693620968127 0.990549673500904 0.990549673500904 0.990549673500904 0.710438842159779 0.990549673500904
Whsc1l1 ENSMUSG00000054823 0.42248651259866 0.927659144367208 0.927659144367208 0.927659144367208 0.834289240651817 0.927659144367208
Smyd3 ENSMUSG00000055067 0.44579048970704 0.655523192190828 0.655523192190828 0.655523192190828 0.464914868467631 0.655523192190828
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Jmjd6 ENSMUSG00000056962 0.420034402732909 0.630051604099364 0.103931571214 0.311794713641999 0.855927780679312 0.855927780679312
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Suv420h2 ENSMUSG00000059851 0.837383680330376 0.837383680330376 0.828142751254817 0.837383680330376 0.524887626690907 0.837383680330376
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Prmt7 ENSMUSG00000060098 0.269662556245471 0.287176433111421 0.0271449951104654 0.0814349853313963 0.287176433111421 0.287176433111421
Dot1l ENSMUSG00000061589 0.504435806113353 0.713518810138284 0.713518810138284 0.713518810138284 0.494387660202947 0.713518810138284
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Msl2 ENSMUSG00000066415 0.924536064943825 0.971666760277029 0.561590614448763 0.971666760277029 0.971666760277029 0.971666760277029
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Transport of Mature mRNA derived from an Intron-Containing Transcript

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Gle1 ENSMUSG00000019715 0.36723349709815 0.558721090746304 0.529966324558345 0.558721090746304 0.558721090746304 0.558721090746304
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

RNA polymerase II transcribes snRNA genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Phax ENSMUSG00000008301 0.593994621681469 0.890991932522203 0.299988765429107 0.890991932522203 0.908834658280149 0.908834658280149
Pou2f2 ENSMUSG00000008496 0.78440929149125 0.799568301739656 0.713183887624394 0.799568301739656 0.799568301739656 0.799568301739656
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Ints9 ENSMUSG00000021975 0.883848910566009 0.883848910566009 0.215446663437689 0.646339990313066 0.669771745593722 0.883848910566009
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Taf8 ENSMUSG00000023980 0.828124441516432 0.828124441516432 0.271482342300993 0.748921555648755 0.49928103709917 0.748921555648755
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ints4 ENSMUSG00000025133 0.63555889649176 0.63555889649176 0.397770259228666 0.596655388842999 0.127894607161556 0.383683821484669
Nabp2 ENSMUSG00000025374 0.880731820019853 0.880731820019853 0.731275523020539 0.880731820019853 0.467153715493259 0.880731820019853
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Rprd1b ENSMUSG00000027651 0.987403179376432 0.987403179376432 0.0127720652161165 0.0383161956483495 0.773218081372242 0.987403179376432
Ints3 ENSMUSG00000027933 0.812771540280415 0.92451428819997 0.116488043451683 0.34946413035505 0.92451428819997 0.92451428819997
Rprd2 ENSMUSG00000028106 0.499429620793092 0.955939609127718 0.908882118075782 0.955939609127718 0.955939609127718 0.955939609127718
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Cpsf3l ENSMUSG00000029034 0.23996748249015 0.359951223735224 0.0865341636468342 0.259602490940503 0.406629341484474 0.406629341484474
Ssu72 ENSMUSG00000029038 0.136242829605009 0.204364244407513 0.0504278103517965 0.151283431055389 0.743144881051361 0.743144881051361
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Rpap2 ENSMUSG00000033773 0.955928538716565 0.955928538716565 0.469746652759616 0.955928538716565 0.728234247481334 0.955928538716565
Ints6 ENSMUSG00000035161 0.148221007726829 0.444663023180488 0.602217565222341 0.773230202783295 0.773230202783295 0.773230202783295
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Srrt ENSMUSG00000037364 0.561548570096883 0.862409581997312 0.574939721331541 0.862409581997312 0.971660703318924 0.971660703318924
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Asun ENSMUSG00000040250 0.572283795940274 0.73127494591286 0.309570181456686 0.73127494591286 0.73127494591286 0.73127494591286
Ints8 ENSMUSG00000040738 0.191439387267038 0.574318161801113 0.949646823023688 0.990553161463228 0.990553161463228 0.990553161463228
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Ints5 ENSMUSG00000071652 0.34473034700903 0.517095520513545 0.115495177311501 0.346485531934502 0.782297835248887 0.782297835248887
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Cell Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ncaph2 ENSMUSG00000008690 0.215376326001663 0.452963279876567 0.301975519917712 0.452963279876567 0.743096857325309 0.743096857325309
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Gorasp2 ENSMUSG00000014959 0.818845463937341 0.818845463937341 0.227420935877475 0.682262807632424 0.731224463471102 0.818845463937341
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Ten1 ENSMUSG00000020778 0.285431653811292 0.428147480716939 0.124023157139567 0.372069471418702 0.46965476586209 0.46965476586209
Ctc1 ENSMUSG00000020898 0.269774256513816 0.404661384770724 0.118344494227704 0.355033482683112 0.96537207799034 0.96537207799034
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Tert ENSMUSG00000021611 0.81582851704757 0.81582851704757 0.701754634531338 0.81582851704757 0.397594673419908 0.81582851704757
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Dyrk1a ENSMUSG00000022897 0.356444805291483 0.761099790833155 0.761099790833155 0.761099790833155 0.618254556879701 0.761099790833155
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Gar1 ENSMUSG00000028010 0.143706972836139 0.431120918508418 0.361201474840207 0.541802212260311 0.871407813680735 0.871407813680735
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Cdc7 ENSMUSG00000029283 0.905754675088245 0.937088160291987 0.937088160291987 0.937088160291987 0.758177847489751 0.937088160291987
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Pot1a ENSMUSG00000029676 0.632850922486848 0.632850922486848 0.504454253028015 0.632850922486848 0.569575432520929 0.632850922486848
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Atrx ENSMUSG00000031229 0.300158520518485 0.450237780777727 0.187424699979752 0.450237780777727 0.812787179355434 0.812787179355434
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Dkc1 ENSMUSG00000031403 0.532640609557704 0.798960914336556 0.49441725517968 0.798960914336556 0.837387171922872 0.837387171922872
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Mau2 ENSMUSG00000031858 0.834298450887605 0.834298450887605 0.452868066498504 0.679302099747755 0.359166882511679 0.679302099747755
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Terf2 ENSMUSG00000031921 0.773244268082692 0.952795428259095 0.899501396840473 0.952795428259095 0.952795428259095 0.952795428259095
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Fkbpl ENSMUSG00000033739 0.522200976154869 0.862104054739938 0.862104054739938 0.862104054739938 0.687192773503887 0.862104054739938
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Rsf1 ENSMUSG00000035623 0.357087591470307 0.53563138720546 0.315273567009673 0.53563138720546 0.943367562764496 0.943367562764496
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Lin37 ENSMUSG00000036845 0.0665870101587646 0.0998805152381469 0.0175068864312451 0.0525206592937352 0.698862462776113 0.698862462776113
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Acd ENSMUSG00000038000 0.367503836873599 0.620144848380297 0.413429898920198 0.620144848380297 0.849744691475226 0.849744691475226
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Rtel1 ENSMUSG00000038685 0.070897854532443 0.212693563597329 0.825064230392867 0.825064230392867 0.524863575011186 0.787295362516779
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mcph1 ENSMUSG00000039842 0.825032084599903 0.896355871343233 0.275019180028792 0.825057540086376 0.896355871343233 0.896355871343233
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Cables1 ENSMUSG00000040957 0.971663259417754 0.971663259417754 0.499395893797283 0.971663259417754 0.912003502782391 0.971663259417754
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Wrap53 ENSMUSG00000041346 0.0339450482091133 0.0519175678607799 0.0346117119071866 0.0519175678607799 0.443219419231118 0.443219419231118
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Obfc1 ENSMUSG00000042694 0.924541609076933 0.924541609076933 0.912001584594762 0.924541609076933 0.178222801705355 0.534668405116065
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Numa1 ENSMUSG00000066306 0.862112472143811 0.862112472143811 0.524888831496724 0.862112472143811 0.621580834430389 0.862112472143811
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

Antigen processing: Ubiquitination & Proteasome degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo9 ENSMUSG00000001366 0.213593913192257 0.460696954000312 0.307131302666875 0.460696954000312 0.940194121838634 0.940194121838634
Npepps ENSMUSG00000001441 0.828113611642018 0.952784933693202 0.464917315303708 0.952784933693202 0.952784933693202 0.952784933693202
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Fbxo11 ENSMUSG00000005371 0.229006001463732 0.687018004391197 0.610471723108175 0.915707584662263 0.933935404170617 0.933935404170617
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Fbxw5 ENSMUSG00000015095 0.312266225489717 0.583363918635638 0.388909279090426 0.583363918635638 0.818437948865218 0.818437948865218
Unkl ENSMUSG00000015127 0.996851177572851 0.996851177572851 0.545614747144691 0.894995396130751 0.596663597420501 0.894995396130751
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Wsb1 ENSMUSG00000017677 0.692964035503656 0.767165274931203 0.621531949939947 0.767165274931203 0.767165274931203 0.767165274931203
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cbll1 ENSMUSG00000020659 0.332798912996212 0.927673693056393 0.927673693056393 0.927673693056393 0.72535227553832 0.927673693056393
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Fbxl20 ENSMUSG00000020883 0.443360548542608 0.72231253977434 0.599400170065276 0.72231253977434 0.72231253977434 0.72231253977434
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Mgrn1 ENSMUSG00000022517 0.305815061085114 0.458722591627671 0.118351209981931 0.355053629945794 0.514627522318353 0.514627522318353
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Lnpep ENSMUSG00000023845 0.0378778232870052 0.113633469861016 0.269723274511539 0.404584911767309 0.880750693978909 0.880750693978909
Ubr2 ENSMUSG00000023977 0.728321543444688 0.728321543444688 0.610514851941879 0.728321543444688 0.704723379510603 0.728321543444688
Rnf138 ENSMUSG00000024317 0.629945031930056 0.944917547895085 0.413388290114401 0.944917547895085 1 1
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Fbxl15 ENSMUSG00000025226 0.307695222968975 0.461542834453462 0.00805888483641587 0.0241766545092476 0.859033170480059 0.859033170480059
Huwe1 ENSMUSG00000025261 0.669851622519722 0.962228686136411 0.962228686136411 0.962228686136411 0.604992885090226 0.962228686136411
Ube3a ENSMUSG00000025326 0.0100021217833753 0.030006365350126 0.0964484346882663 0.144672652032399 0.522158709680698 0.522158709680698
Rnf41 ENSMUSG00000025373 0.918271852600076 0.918271852600076 0.825079431949656 0.918271852600076 0.716480625543547 0.918271852600076
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Rnf25 ENSMUSG00000026171 0.722329734065528 0.981104486388196 0.687145764567564 0.981104486388196 0.981104486388196 0.981104486388196
Trip12 ENSMUSG00000026219 0.31527763384103 0.707623507301317 0.594013590497052 0.707623507301317 0.707623507301317 0.707623507301317
Asb1 ENSMUSG00000026311 0.601944165244773 0.601944165244773 0.0636532260572407 0.190959678171722 0.454867103954538 0.601944165244773
Klhl20 ENSMUSG00000026705 0.519684141499169 0.695920118882848 0.496896837138848 0.695920118882848 0.695920118882848 0.695920118882848
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Ubr1 ENSMUSG00000027272 0.469759818197924 0.580387749709864 0.530051937757425 0.580387749709864 0.580387749709864 0.580387749709864
Ubox5 ENSMUSG00000027300 0.289246626019819 0.433869939029728 0.752174358730662 0.752174358730662 0.170623956292642 0.433869939029728
Rbck1 ENSMUSG00000027466 0.26432804499609 0.646757686737436 0.646757686737436 0.646757686737436 0.504183875642183 0.646757686737436
Ube2j1 ENSMUSG00000028277 0.472189545060989 0.96851806962253 0.96851806962253 0.96851806962253 0.719407192774666 0.96851806962253
Rnf220 ENSMUSG00000028677 0.566892123333099 0.850338184999648 0.479520836960388 0.850338184999648 0.959081732985053 0.959081732985053
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Mib2 ENSMUSG00000029060 0.450479828987673 0.675719743481509 0.236789471977911 0.675719743481509 0.704639605500424 0.704639605500424
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Glmn ENSMUSG00000029276 0.616066355828508 0.669836942837089 0.369647542185504 0.669836942837089 0.669836942837089 0.669836942837089
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Rnf6 ENSMUSG00000029634 0.0149513282232087 0.0448539846696261 0.0603000662838841 0.0904500994258261 0.846617386793513 0.846617386793513
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Mkrn1 ENSMUSG00000029922 0.216490221537255 0.324735332305882 0.118244827676101 0.324735332305882 0.61016482119888 0.61016482119888
Fbxl14 ENSMUSG00000030019 0.585733426897513 0.878600140346269 0.296343958092929 0.878600140346269 0.912009716457441 0.912009716457441
Kbtbd8 ENSMUSG00000030031 0.566939894440354 0.737225190462243 0.737225190462243 0.737225190462243 0.707644415368941 0.737225190462243
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Asb7 ENSMUSG00000030509 0.886996648412827 0.886996648412827 0.722376332987625 0.886996648412827 0.855908935982981 0.886996648412827
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Rbbp6 ENSMUSG00000030779 0.831182834902999 0.831182834902999 0.764140628139708 0.831182834902999 0.758082080951701 0.831182834902999
Fbxl19 ENSMUSG00000030811 0.859032111304213 0.859032111304213 0.624401770964706 0.859032111304213 0.821993934939889 0.859032111304213
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Ube2cbp ENSMUSG00000032415 0.246222587997866 0.545451973176 0.472046787651495 0.545451973176 0.545451973176 0.545451973176
Uba5 ENSMUSG00000032557 0.21245362762891 0.637360882886731 0.675607997039037 0.965372819853871 0.965372819853871 0.965372819853871
Traip ENSMUSG00000032586 0.415002383672552 0.625690789604884 0.417127193069923 0.625690789604884 0.739816268845056 0.739816268845056
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Trim36 ENSMUSG00000033949 0.981107319702807 0.981107319702807 0.949644952980045 0.981107319702807 0.828122608330827 0.981107319702807
Hectd1 ENSMUSG00000035247 0.0506398787063026 0.151919636118908 0.996848007433573 0.996848007433573 0.157356304443767 0.23603445666565
Rnf126 ENSMUSG00000035890 0.886883315975953 0.886883315975953 0.767054704087373 0.886883315975953 0.276331251365775 0.828993754097326
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Siah1a ENSMUSG00000036840 0.713481603401334 0.766960237832609 0.601996199580706 0.766960237832609 0.766960237832609 0.766960237832609
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Mex3c ENSMUSG00000037253 0.553615741912637 0.818915481821514 0.818915481821514 0.818915481821514 0.701727917939143 0.818915481821514
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Herc1 ENSMUSG00000038664 0.26109821284758 0.783294638542741 0.734165220730748 0.843515288270164 0.843515288270164 0.843515288270164
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Hace1 ENSMUSG00000038822 0.773234390624075 0.773234390624075 0.282065707839971 0.773234390624075 0.770225804325364 0.773234390624075
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Asb6 ENSMUSG00000039483 0.918255734950225 0.918255734950225 0.862104557997622 0.918255734950225 0.692981424119149 0.918255734950225
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Fbxl5 ENSMUSG00000039753 0.460089905660059 0.527349966742554 0.382374381325839 0.527349966742554 0.527349966742554 0.527349966742554
Spsb1 ENSMUSG00000039911 0.319080089631295 0.580187025826347 0.865240833296443 0.865240833296443 0.386791350550898 0.580187025826347
Klhl42 ENSMUSG00000040102 0.472026108099081 0.868301215980349 0.868301215980349 0.868301215980349 0.776168664106968 0.868301215980349
Vprbp ENSMUSG00000040325 0.408731381241263 0.613097071861894 0.159571603950442 0.478714811851326 0.981095497003617 0.981095497003617
Ufl1 ENSMUSG00000040359 0.00154014050357583 0.00231021075536375 0.000299240768687186 0.000897722306061557 0.666816357599575 0.666816357599575
Trim41 ENSMUSG00000040365 0.599413027950627 0.952785966083281 0.952785966083281 0.952785966083281 0.862125948978978 0.952785966083281
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Fbxw4 ENSMUSG00000040913 0.0822124854277177 0.224008023834634 0.149338682556422 0.224008023834634 0.707633447761154 0.707633447761154
Wwp1 ENSMUSG00000041058 0.241489491015698 0.724468473047093 0.91826132991022 0.924534880356959 0.924534880356959 0.924534880356959
Tpp2 ENSMUSG00000041763 0.00435896654734185 0.0130768996420256 0.4745482659838 0.4745482659838 0.330764465635496 0.4745482659838
Arel1 ENSMUSG00000042350 0.776265111300032 0.776265111300032 0.424780757679406 0.675781994624233 0.450521329749489 0.675781994624233
Ube2q1 ENSMUSG00000042572 0.59923306870678 0.874455317143018 0.450530094906324 0.874455317143018 0.874455317143018 0.874455317143018
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Ltn1 ENSMUSG00000052299 0.436301373539077 0.846653790576662 0.767182147528682 0.846653790576662 0.846653790576662 0.846653790576662
Gan ENSMUSG00000052557 0.313344114171842 0.470016171257763 0.26299500485965 0.470016171257763 0.681391720765928 0.681391720765928
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Klhl5 ENSMUSG00000054920 0.441023563137958 0.556142046462253 0.540328093857368 0.556142046462253 0.556142046462253 0.556142046462253
Fbxo6 ENSMUSG00000055401 0.165725488149896 0.344494721839957 0.307467389409342 0.344494721839957 0.344494721839957 0.344494721839957
Klhl25 ENSMUSG00000055652 0.0531566348600952 0.159469904580285 0.219797201332521 0.329695801998782 0.342050703942181 0.342050703942181
Rlim ENSMUSG00000056537 0.170643280526332 0.350498044647242 0.233665363098161 0.350498044647242 0.937084234672894 0.937084234672894
Ube4a ENSMUSG00000059890 0.0880020106174511 0.264006031852353 0.930788868983936 0.930788868983936 0.340650207372243 0.510975311058364
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Arih2 ENSMUSG00000064145 0.231992720716999 0.347989081075498 0.129045338495288 0.347989081075498 0.782209240815231 0.782209240815231
Ubr4 ENSMUSG00000066036 0.911955765287219 0.911955765287219 0.752169941463026 0.911955765287219 0.73707734465406 0.911955765287219
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Fbxl12 ENSMUSG00000066892 0.514569590928347 0.771854386392521 0.968518283937401 0.968518283937401 0.404276434285822 0.771854386392521
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Ube2v1 ENSMUSG00000078923 0.707651456421661 0.707651456421661 0.0690119256001669 0.207035776800501 0.649779661098828 0.707651456421661
Fbxw10 ENSMUSG00000090173 0.74415417304833 0.74415417304833 0.635518344743522 0.74415417304833 0.729025476397157 0.74415417304833
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

DNA Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Paxip1 ENSMUSG00000002221 0.843499529111168 0.940196430274366 0.701636481517852 0.940196430274366 0.940196430274366 0.940196430274366
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Ppp5c ENSMUSG00000003099 0.734155957610943 0.855937200255394 0.855937200255394 0.855937200255394 0.754985282103299 0.855937200255394
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Ufd1l ENSMUSG00000005262 0.591252229789365 0.591252229789365 0.328797396458557 0.591252229789365 0.434033727036496 0.591252229789365
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Fance ENSMUSG00000007570 0.095706501306675 0.287119503920025 0.393223216571204 0.589834824856806 0.855882327545643 0.855882327545643
Rad51c ENSMUSG00000007646 0.558862186064833 0.88698773329794 0.88698773329794 0.88698773329794 0.649708749511075 0.88698773329794
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Eya2 ENSMUSG00000017897 0.883900275850861 0.883900275850861 0.574973102444853 0.883900275850861 0.868343217484915 0.883900275850861
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Rev3l ENSMUSG00000019841 0.698836320625326 0.698836320625326 0.344802224705691 0.698836320625326 0.62441091085238 0.698836320625326
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Mpg ENSMUSG00000020287 0.112717910173475 0.338153730520425 0.467184525231011 0.467184525231011 0.391150604080965 0.467184525231011
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Xrcc3 ENSMUSG00000021287 0.256280686890594 0.716466352440455 0.596743151103392 0.716466352440455 0.716466352440455 0.716466352440455
Fancc ENSMUSG00000021461 0.10483914522132 0.314517435663961 0.4869456968576 0.566921429433929 0.566921429433929 0.566921429433929
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Parg ENSMUSG00000021911 0.342761559060323 0.893241911070194 0.843557829752659 0.893241911070194 0.893241911070194 0.893241911070194
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Msh2 ENSMUSG00000024151 0.604959112145457 0.874534811529155 0.274958891021396 0.824876673064189 0.874534811529155 0.874534811529155
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Mus81 ENSMUSG00000024906 0.317161644537185 0.317161644537185 0.309558578812616 0.317161644537185 0.309567687476581 0.317161644537185
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Poll ENSMUSG00000025218 0.0265647205428424 0.0398470808142636 0.0126226286012384 0.0378678858037152 0.411124104047638 0.411124104047638
2310003H01Rik ENSMUSG00000025384 0.324918975433978 0.487378463150967 0.166897119453255 0.487378463150967 0.591192347167402 0.591192347167402
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rev1 ENSMUSG00000026082 0.77323705101421 0.79446707642379 0.749164886040425 0.79446707642379 0.79446707642379 0.79446707642379
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Dclre1c ENSMUSG00000026648 0.791349536535927 0.791349536535927 0.183165715330873 0.549497145992619 0.545547743610266 0.791349536535927
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Fancg ENSMUSG00000028453 0.632842106829348 0.800580125546944 0.303934036067089 0.800580125546944 0.800580125546944 0.800580125546944
Eya3 ENSMUSG00000028886 0.354939940500405 0.499334371435975 0.438729069044625 0.499334371435975 0.499334371435975 0.499334371435975
Xrcc2 ENSMUSG00000028933 0.630043038404972 0.630043038404972 0.580403913049553 0.630043038404972 0.545715713606246 0.630043038404972
Mad2l2 ENSMUSG00000029003 0.0163341725967249 0.0490025177901746 0.211013925138425 0.316520887707637 0.794360760642728 0.794360760642728
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Pot1a ENSMUSG00000029676 0.632850922486848 0.632850922486848 0.504454253028015 0.632850922486848 0.569575432520929 0.632850922486848
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Rad18 ENSMUSG00000030254 0.274811771450367 0.577392108098863 0.450487835959263 0.577392108098863 0.577392108098863 0.577392108098863
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Usp10 ENSMUSG00000031826 0.431196316155006 0.704660933121012 0.704660933121012 0.704660933121012 0.658011866762809 0.704660933121012
Terf2 ENSMUSG00000031921 0.773244268082692 0.952795428259095 0.899501396840473 0.952795428259095 0.952795428259095 0.952795428259095
Sprtn ENSMUSG00000031986 0.927644151486374 0.927644151486374 0.837349092467287 0.927644151486374 0.61861344160607 0.927644151486374
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Fan1 ENSMUSG00000033458 0.0895463814162714 0.268639144248814 0.535210742769633 0.535210742769633 0.417936826467238 0.535210742769633
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Fancd2 ENSMUSG00000034023 0.971642734179405 0.971642734179405 0.933888899380019 0.971642734179405 0.818914011107705 0.971642734179405
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Sirt6 ENSMUSG00000034748 0.198275859846668 0.594827579540004 0.83121063778572 0.83121063778572 0.74016838660268 0.83121063778572
Apex1 ENSMUSG00000035960 0.902621697762315 0.902621697762315 0.627244507954548 0.902621697762315 0.877671448543678 0.902621697762315
Smug1 ENSMUSG00000036061 0.971658624396913 0.971658624396913 0.791374158881171 0.971658624396913 0.376034605394662 0.971658624396913
Rif1 ENSMUSG00000036202 0.289206890832308 0.433810336248461 0.249649284946705 0.433810336248461 0.719440962207448 0.719440962207448
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Acd ENSMUSG00000038000 0.367503836873599 0.620144848380297 0.413429898920198 0.620144848380297 0.849744691475226 0.849744691475226
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Nploc4 ENSMUSG00000039703 0.0734616307314732 0.11019244609721 0.0329519126927198 0.0988557380781594 0.663343302694908 0.663343302694908
Slx4 ENSMUSG00000039738 0.472155600959342 0.865220680142318 0.728303881107593 0.865220680142318 0.865220680142318 0.865220680142318
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Usp45 ENSMUSG00000040455 0.427099674201283 0.981105959111385 0.868332276481305 0.981105959111385 0.981105959111385 0.981105959111385
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Adprhl2 ENSMUSG00000042558 0.0491726109246117 0.147517832773835 0.152714268037273 0.22907140205591 0.585806673257651 0.585806673257651
Lig4 ENSMUSG00000049717 0.0926013994713989 0.277804198414197 0.94961238758366 0.94961238758366 0.812692402337864 0.94961238758366
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Xrcc1 ENSMUSG00000051768 0.373889676064885 0.560834514097327 0.311472140296653 0.560834514097327 0.782330754853731 0.782330754853731
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Fancm ENSMUSG00000055884 0.952794070099461 0.952794070099461 0.707657842777675 0.952794070099461 0.632848414648752 0.952794070099461
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Slx1b ENSMUSG00000059772 0.273102203263939 0.819306609791816 0.809671281226618 0.955923206999278 0.955923206999278 0.955923206999278
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Eme2 ENSMUSG00000073436 0.484457700482441 0.794981788107556 0.84354063447501 0.84354063447501 0.52998785873837 0.794981788107556
2610002J02Rik ENSMUSG00000073684 0.0290901818140466 0.0872705454421397 0.0653888008597837 0.0980832012896756 0.616061269615089 0.616061269615089
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Fancf ENSMUSG00000092118 0.214013296666816 0.478566931506538 0.319044621004358 0.478566931506538 0.629979851869174 0.629979851869174
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

SUMOylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dnmt1 ENSMUSG00000004099 0.577555858074608 0.635538036514718 0.457685292289755 0.635538036514718 0.635538036514718 0.635538036514718
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Top2b ENSMUSG00000017485 0.621570154742956 0.970443928900233 0.646962619266822 0.970443928900233 0.977954326966792 0.977954326966792
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Senp5 ENSMUSG00000022772 0.322987682059722 0.803627553914552 0.803627553914552 0.803627553914552 0.627228423353243 0.803627553914552
Senp2 ENSMUSG00000022855 0.318959073507393 0.523070923993142 0.348713949328761 0.523070923993142 0.924493561362545 0.924493561362545
Satb1 ENSMUSG00000023927 0.94651011695288 0.971665729445135 0.803624675438964 0.971665729445135 0.971665729445135 0.971665729445135
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Uhrf2 ENSMUSG00000024817 0.915142256744398 0.915142256744398 0.649828919527377 0.915142256744398 0.550973357034918 0.915142256744398
Smc5 ENSMUSG00000024943 0.450479271527473 0.661222470513607 0.535252137809611 0.661222470513607 0.661222470513607 0.661222470513607
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Park7 ENSMUSG00000028964 0.100193509532914 0.300580528598743 0.340072180267643 0.501892715742569 0.501892715742569 0.501892715742569
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Satb2 ENSMUSG00000038331 0.701180780170431 0.949531112457672 0.949531112457672 0.949531112457672 0.727458227478397 0.949531112457672
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Ddx17 ENSMUSG00000055065 0.828152914507463 0.871447107023116 0.871447107023116 0.871447107023116 0.489429050732231 0.871447107023116
Nsmce2 ENSMUSG00000059586 0.424673594011485 0.655411431505958 0.556173761323834 0.655411431505958 0.655411431505958 0.655411431505958
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Ndnl2 ENSMUSG00000070520 0.655479660571186 0.776254822726478 0.190002999328858 0.570008997986575 0.776254822726478 0.776254822726478
Top1 ENSMUSG00000070544 0.0524875749189175 0.157462724756753 0.865185136694549 0.981099842312976 0.981099842312976 0.981099842312976
Safb ENSMUSG00000071054 0.574823745567258 0.883875670750215 0.825027507382374 0.883875670750215 0.883875670750215 0.883875670750215
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Zfp131 ENSMUSG00000094870 0.201075240296991 0.464329328589451 0.3095528857263 0.464329328589451 0.621633089534301 0.621633089534301

SUMO E3 ligases SUMOylate target proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dnmt1 ENSMUSG00000004099 0.577555858074608 0.635538036514718 0.457685292289755 0.635538036514718 0.635538036514718 0.635538036514718
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Top2b ENSMUSG00000017485 0.621570154742956 0.970443928900233 0.646962619266822 0.970443928900233 0.977954326966792 0.977954326966792
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Hdac7 ENSMUSG00000022475 0.107467050047572 0.322401150142716 0.527466948183819 0.527466948183819 0.417942349123919 0.527466948183819
Satb1 ENSMUSG00000023927 0.94651011695288 0.971665729445135 0.803624675438964 0.971665729445135 0.971665729445135 0.971665729445135
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Uhrf2 ENSMUSG00000024817 0.915142256744398 0.915142256744398 0.649828919527377 0.915142256744398 0.550973357034918 0.915142256744398
Smc5 ENSMUSG00000024943 0.450479271527473 0.661222470513607 0.535252137809611 0.661222470513607 0.661222470513607 0.661222470513607
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Park7 ENSMUSG00000028964 0.100193509532914 0.300580528598743 0.340072180267643 0.501892715742569 0.501892715742569 0.501892715742569
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Tdg ENSMUSG00000034674 0.504391563341428 0.756587345012142 1 1 0.494292032823192 0.756587345012142
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Satb2 ENSMUSG00000038331 0.701180780170431 0.949531112457672 0.949531112457672 0.949531112457672 0.727458227478397 0.949531112457672
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Ddx17 ENSMUSG00000055065 0.828152914507463 0.871447107023116 0.871447107023116 0.871447107023116 0.489429050732231 0.871447107023116
Nsmce2 ENSMUSG00000059586 0.424673594011485 0.655411431505958 0.556173761323834 0.655411431505958 0.655411431505958 0.655411431505958
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Ndnl2 ENSMUSG00000070520 0.655479660571186 0.776254822726478 0.190002999328858 0.570008997986575 0.776254822726478 0.776254822726478
Top1 ENSMUSG00000070544 0.0524875749189175 0.157462724756753 0.865185136694549 0.981099842312976 0.981099842312976 0.981099842312976
Safb ENSMUSG00000071054 0.574823745567258 0.883875670750215 0.825027507382374 0.883875670750215 0.883875670750215 0.883875670750215
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Zfp131 ENSMUSG00000094870 0.201075240296991 0.464329328589451 0.3095528857263 0.464329328589451 0.621633089534301 0.621633089534301

Membrane Trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Hip1r ENSMUSG00000000915 0.545683876865408 0.996850730657377 0.974810147975717 0.996850730657377 0.996850730657377 0.996850730657377
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rin2 ENSMUSG00000001768 0.877666542586628 0.877666542586628 0.73399696152476 0.877666542586628 0.386418764761682 0.877666542586628
Ap4e1 ENSMUSG00000001998 0.865244022390156 0.865244022390156 0.537859075080974 0.865244022390156 0.632859091603956 0.865244022390156
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Ap1m1 ENSMUSG00000003033 0.852763396074851 0.852763396074851 0.460085037463511 0.852763396074851 0.5694284648412 0.852763396074851
Sh3gl1 ENSMUSG00000003200 0.734257170446249 0.734257170446249 0.404418970770285 0.606628456155427 0.397733389607841 0.606628456155427
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Ap1s1 ENSMUSG00000004849 0.599494473380636 0.899241710070954 0.338774886348955 0.899241710070954 0.996851223624921 0.996851223624921
Ubqln1 ENSMUSG00000005312 0.886984660793428 0.886984660793428 0.201083689829996 0.603251069489988 0.764118582319767 0.886984660793428
Pafah1b3 ENSMUSG00000005447 0.429431168017631 0.687130134373971 0.687130134373971 0.687130134373971 0.627161792520192 0.687130134373971
Bloc1s6 ENSMUSG00000005804 0.731244815731594 0.731244815731594 0.123057122168857 0.36917136650657 0.273190456560293 0.409785684840439
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Snf8 ENSMUSG00000006058 0.012863396720729 0.0192950950810935 0.00170650025632417 0.00511950076897252 0.824991011420563 0.824991011420563
Eps15l1 ENSMUSG00000006276 0.785251119050755 0.785251119050755 0.666888813786863 0.785251119050755 0.731161645452711 0.785251119050755
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ap1b1 ENSMUSG00000009090 0.350802381985732 0.526203572978598 0.0525017105892906 0.157505131767872 0.621585745224902 0.621585745224902
Kif19a ENSMUSG00000010021 0.707571700801429 0.809347792166954 0.754701535164911 0.809347792166954 0.809347792166954 0.809347792166954
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Tsg101 ENSMUSG00000014402 0.202477913474612 0.607433740423835 0.949645396642883 0.949645396642883 0.638440217186756 0.949645396642883
Gdi1 ENSMUSG00000015291 0.97796043059637 0.97796043059637 0.484431605352091 0.726647408028137 0.350907015843479 0.726647408028137
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Pacsin2 ENSMUSG00000016664 0.770104729886689 0.849665402660967 0.0513047073248464 0.153914121974539 0.849665402660967 0.849665402660967
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Vps53 ENSMUSG00000017288 0.377941116190403 0.566911674285605 0.0918141240913908 0.275442372274172 0.974802785331107 0.974802785331107
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ap4m1 ENSMUSG00000019518 0.693012188876577 0.865241787067826 0.865241787067826 0.865241787067826 0.384630371524433 0.865241787067826
Reps1 ENSMUSG00000019854 0.675605194706463 0.675605194706463 0.307509707177996 0.675605194706463 0.479423697740017 0.675605194706463
Vta1 ENSMUSG00000019868 0.113723374771379 0.170585062157068 0.0473505327846662 0.142051598353999 0.788371093113175 0.788371093113175
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Nbas ENSMUSG00000020576 0.831199458852206 0.831199458852206 0.0753846720564074 0.226154016169222 0.247920106909697 0.371880160364545
Trappc12 ENSMUSG00000020628 0.443387078271416 0.443387078271416 0.19006612444106 0.443387078271416 0.438716878108443 0.443387078271416
Cpd ENSMUSG00000020841 0.219666804573896 0.659000413721689 0.764022936291115 0.764022936291115 0.731291132373729 0.764022936291115
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Vamp2 ENSMUSG00000020894 0.713533370673868 0.871452400328244 0.871452400328244 0.871452400328244 0.58854331361707 0.871452400328244
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Trappc13 ENSMUSG00000021711 0.094972509193824 0.284917527581472 0.378120241073486 0.567180361610229 0.613294786270333 0.613294786270333
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
App ENSMUSG00000022892 0.669837081661211 0.704724196773938 0.332776383296367 0.704724196773938 0.704724196773938 0.704724196773938
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Bnip1 ENSMUSG00000024191 0.0346582671987526 0.0709621643207598 0.0473081095471732 0.0709621643207598 0.489381298258457 0.489381298258457
Vps52 ENSMUSG00000024319 0.621367928119512 0.788281082479196 0.357097229975649 0.788281082479196 0.788281082479196 0.788281082479196
Bin1 ENSMUSG00000024381 0.574927196052138 0.577653294094102 0.373888017702025 0.577653294094102 0.577653294094102 0.577653294094102
Ap3s1 ENSMUSG00000024480 0.514586521057514 0.771879781586271 0.4919120079912 0.771879781586271 0.862122885023046 0.862122885023046
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Vps51 ENSMUSG00000024797 0.105653507029143 0.310135981870419 0.206757321246946 0.310135981870419 0.38454930818886 0.38454930818886
Adrbk1 ENSMUSG00000024858 0.361229869200603 0.541844803800904 0.307695006136241 0.541844803800904 0.632826791918313 0.632826791918313
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Agfg1 ENSMUSG00000026159 0.116488537274731 0.349465611824193 0.69301316538426 0.69301316538426 0.406625612113968 0.609938418170952
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Golga1 ENSMUSG00000026754 0.211073540781294 0.316610311171941 0.158430081793005 0.316610311171941 0.43174020429507 0.43174020429507
Tor1b ENSMUSG00000026848 0.661171530407166 0.661171530407166 0.352849812994504 0.661171530407166 0.457643731257813 0.661171530407166
Gapvd1 ENSMUSG00000026867 0.69300453924434 0.69300453924434 0.340587538987273 0.69300453924434 0.489343980904243 0.69300453924434
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Ubap1 ENSMUSG00000028437 0.314201676680708 0.471302515021063 0.0127694601790513 0.038308380537154 0.74564890402646 0.74564890402646
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Eps15 ENSMUSG00000028552 0.23839979523243 0.715199385697289 0.527457391543817 0.791186087315726 0.86523993911738 0.86523993911738
Pum1 ENSMUSG00000028580 0.977950194294777 0.977950194294777 0.501846360670251 0.977950194294777 0.824956148679795 0.977950194294777
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Rint1 ENSMUSG00000028999 0.937073603772649 0.937073603772649 0.422451096973321 0.937073603772649 0.852843783462489 0.937073603772649
Stx18 ENSMUSG00000029125 0.309581512482546 0.737857261122885 0.927674707753686 0.927674707753686 0.49190484074859 0.737857261122885
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Gcc1 ENSMUSG00000029708 0.464741208485198 0.698842272802265 0.698842272802265 0.698842272802265 0.613122438466004 0.698842272802265
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Tmf1 ENSMUSG00000030059 0.0268244330294316 0.080473299088295 0.469722256882648 0.704583385323973 0.946493484550472 0.946493484550472
Stx4a ENSMUSG00000030805 0.583114701383756 0.583114701383756 0.545715758505275 0.583114701383756 0.535245520817248 0.583114701383756
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Arfip2 ENSMUSG00000030881 0.968488970040684 0.968488970040684 0.672464777544939 0.968488970040684 0.655477247667167 0.968488970040684
Cttn ENSMUSG00000031078 0.890132912119958 0.890132912119958 0.550893815794547 0.890132912119958 0.752121469870449 0.890132912119958
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Ap1g1 ENSMUSG00000031731 0.17807043340121 0.534211300203631 0.60488766421616 0.60488766421616 0.542679833235013 0.60488766421616
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Kif9 ENSMUSG00000032489 0.852651985562056 0.95277494340192 0.95277494340192 0.95277494340192 0.893051561758697 0.95277494340192
Trappc8 ENSMUSG00000033382 0.138229469212802 0.414688407638407 0.949638566305517 0.949638566305517 0.604694278613409 0.907041417920113
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Tbc1d10a ENSMUSG00000034412 0.602137687009539 0.740181369489312 0.45756491055059 0.740181369489312 0.740181369489312 0.740181369489312
Ankrd27 ENSMUSG00000034867 0.569569563592984 0.627210181364254 0.348839987958392 0.627210181364254 0.627210181364254 0.627210181364254
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Epn1 ENSMUSG00000035203 0.486916318044524 0.489403403033323 0.162096873199981 0.486290619599942 0.489403403033323 0.489403403033323
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Bicd2 ENSMUSG00000037933 0.188558410070277 0.422937960694121 0.281958640462747 0.422937960694121 0.692946871935085 0.692946871935085
Trappc11 ENSMUSG00000038102 0.740092016826772 0.740092016826772 0.457621085091718 0.740092016826772 0.629928919607601 0.740092016826772
Sbf2 ENSMUSG00000038371 0.908873953217301 0.908873953217301 0.890136154521336 0.908873953217301 0.35705797334954 0.908873953217301
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Tbc1d17 ENSMUSG00000038520 0.10144889267115 0.304346678013449 0.313373449998798 0.470060174998197 0.79137614013413 0.79137614013413
Arfrp1 ENSMUSG00000038671 0.320994413286289 0.481491619929434 0.122042650948381 0.366127952845144 0.749059059663526 0.749059059663526
Tbc1d25 ENSMUSG00000039201 0.402038402236954 0.830350784447286 0.553567189631524 0.830350784447286 0.883879804882268 0.883879804882268
Tbc1d2 ENSMUSG00000039813 0.354999710776454 0.651064940968246 0.434043293978831 0.651064940968246 0.896375251853633 0.896375251853633
Hip1 ENSMUSG00000039959 0.911982660237219 0.911982660237219 0.641239476621553 0.911982660237219 0.893244435404828 0.911982660237219
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Adrbk2 ENSMUSG00000042249 0.905704972160358 0.933950881520103 0.550754227659045 0.933950881520103 0.933950881520103 0.933950881520103
Hps4 ENSMUSG00000042328 0.464810672479667 0.632782508531239 0.113690003833535 0.341070011500605 0.632782508531239 0.632782508531239
Tbc1d10b ENSMUSG00000042492 0.362986514683911 0.544479772025867 0.328794307304242 0.544479772025867 0.757959235020951 0.757959235020951
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Sys1 ENSMUSG00000045503 0.0152643007233324 0.0228964510849985 0.00330599018088915 0.00991797054266744 0.821986076879709 0.821986076879709
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Vps37c ENSMUSG00000048832 0.899346352716889 0.899346352716889 0.307560750119503 0.899346352716889 0.701356730347006 0.899346352716889
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
Dennd4a ENSMUSG00000053641 0.506787812327301 0.768006652621308 0.98425081610098 0.98425081610098 0.512004435080872 0.768006652621308
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Bloc1s3 ENSMUSG00000057667 0.550914796314054 0.826372194471081 0.427121710263959 0.826372194471081 0.949651224946529 0.949651224946529
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Kif13b ENSMUSG00000060012 0.825065979446263 0.825065979446263 0.758155212029761 0.825065979446263 0.649810810611423 0.825065979446263
Kif27 ENSMUSG00000060176 0.90794064172691 0.974602699673214 0.583115579423678 0.974602699673214 0.974602699673214 0.974602699673214
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Bloc1s4 ENSMUSG00000060708 0.899428444594652 0.899428444594652 0.0822220949456355 0.246666284836907 0.791309498080764 0.899428444594652
Arl1 ENSMUSG00000060904 0.977954922786188 0.977954922786188 0.883883578019259 0.977954922786188 0.369504346512649 0.977954922786188
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902
Fcho1 ENSMUSG00000070000 0.375726943718728 0.943333432449234 0.689872232697787 0.943333432449234 0.943333432449234 0.943333432449234
Rabepk ENSMUSG00000070953 0.230468444889404 0.345702667334107 0.113689596861401 0.341068790584202 0.49433381603067 0.49433381603067
Fnbp1 ENSMUSG00000075415 0.79143887338941 0.79143887338941 0.737225699259388 0.79143887338941 0.618846781755802 0.79143887338941
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Mon1b ENSMUSG00000078908 0.77626936738718 0.977961380140919 0.785360586740878 0.977961380140919 0.977961380140919 0.977961380140919
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298

SUMOylation of RNA binding proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Hnrnpk ENSMUSG00000021546 0.713452096975895 0.713452096975895 0.627216300810166 0.713452096975895 0.476910105567773 0.713452096975895
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Hnrnpc ENSMUSG00000060373 0.232090678867236 0.696272036601707 0.877666651011947 0.877666651011947 0.812804660926203 0.877666651011947
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

mRNA 3’-end processing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

SUMOylation of chromatin organization proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Satb1 ENSMUSG00000023927 0.94651011695288 0.971665729445135 0.803624675438964 0.971665729445135 0.971665729445135 0.971665729445135
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Satb2 ENSMUSG00000038331 0.701180780170431 0.949531112457672 0.949531112457672 0.949531112457672 0.727458227478397 0.949531112457672
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Transport of Mature mRNA Derived from an Intronless Transcript

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Deubiquitination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Ufd1l ENSMUSG00000005262 0.591252229789365 0.591252229789365 0.328797396458557 0.591252229789365 0.434033727036496 0.591252229789365
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Usp19 ENSMUSG00000006676 0.555985360729751 0.743015676480996 0.092602981624798 0.277808944874394 0.743015676480996 0.743015676480996
Stambp ENSMUSG00000006906 0.684279337916864 0.684279337916864 0.681389164199228 0.684279337916864 0.574989725969528 0.684279337916864
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Uchl5 ENSMUSG00000018189 0.219896114839815 0.525896260581595 0.350597507054397 0.525896260581595 0.76099969924541 0.76099969924541
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Fkbp8 ENSMUSG00000019428 0.0754988039267296 0.226496411780189 0.397661585885481 0.501093706078811 0.501093706078811 0.501093706078811
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Atxn3 ENSMUSG00000021189 0.564244882287197 0.719435649957634 0.719435649957634 0.719435649957634 0.664079906534046 0.719435649957634
Traf3 ENSMUSG00000021277 0.996851024285757 0.996851024285757 0.50951720821185 0.996851024285757 0.974813654004815 0.996851024285757
Atxn7 ENSMUSG00000021738 0.300230842914402 0.900692528743205 0.773245376445156 0.921407802086672 0.921407802086672 0.921407802086672
Bap1 ENSMUSG00000021901 0.413407788783879 0.620111683175819 0.108343937037946 0.325031811113838 0.797530303516965 0.797530303516965
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Josd1 ENSMUSG00000022426 0.883902927272286 0.883902927272286 0.0386462576960662 0.115938773088198 0.72239476386854 0.883902927272286
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Otub1 ENSMUSG00000024767 0.2998765079153 0.2998765079153 0.185928139933512 0.2998765079153 0.250990052949487 0.2998765079153
Stambpl1 ENSMUSG00000024776 0.927676382716097 0.927676382716097 0.749167566537165 0.927676382716097 0.737218377949268 0.927676382716097
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Rce1 ENSMUSG00000024889 0.556266879142241 0.834400318713362 0.110081838544872 0.330245515634615 0.990553944009068 0.990553944009068
Mbd6 ENSMUSG00000025409 0.678201875842515 0.962204370529384 0.162065246181141 0.486195738543423 0.962204370529384 0.962204370529384
Usp33 ENSMUSG00000025437 0.491903194177525 0.737854791266288 0.908875584338405 0.908875584338405 0.484443431720096 0.737854791266288
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Usp16 ENSMUSG00000025616 0.641287562523823 0.641287562523823 0.261021554656134 0.641287562523823 0.632763573931717 0.641287562523823
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Usp24 ENSMUSG00000028514 0.80665519534199 0.874551056307771 0.326891407506396 0.874551056307771 0.874551056307771 0.874551056307771
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Tada2b ENSMUSG00000029196 0.406557368296659 0.693030382940719 0.693030382940719 0.693030382940719 0.610435525360737 0.693030382940719
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Usp12 ENSMUSG00000029640 0.779285739065985 0.915135318836707 0.862138477061457 0.915135318836707 0.915135318836707 0.915135318836707
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Usp10 ENSMUSG00000031826 0.431196316155006 0.704660933121012 0.704660933121012 0.704660933121012 0.658011866762809 0.704660933121012
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Usp4 ENSMUSG00000032612 0.476276255657081 0.669269987649272 0.213927345158588 0.641782035475763 0.669269987649272 0.669269987649272
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Usp37 ENSMUSG00000033364 0.157368156181812 0.472104468545437 0.940226488909329 0.940226488909329 0.834308461857482 0.940226488909329
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Cyld ENSMUSG00000036712 0.893249471687713 0.98110763185907 0.773243036549786 0.98110763185907 0.98110763185907 0.98110763185907
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Otud7b ENSMUSG00000038495 0.655377085525873 0.849652001261297 0.669727460305022 0.849652001261297 0.849652001261297 0.849652001261297
Josd2 ENSMUSG00000038695 0.320854786789104 0.320854786789104 0.012772647551706 0.038317942655118 0.221300509313193 0.320854786789104
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Adrm1 ENSMUSG00000039041 0.104965021816539 0.157447532724809 0.0397463098480413 0.119238929544124 0.571749204282725 0.571749204282725
Foxk2 ENSMUSG00000039275 0.49692369178867 0.815866894959488 0.815866894959488 0.815866894959488 0.800575809275715 0.815866894959488
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Mat2b ENSMUSG00000042032 0.42020009065683 0.630300135985245 0.908878380342246 0.908878380342246 0.411153687199577 0.630300135985245
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Asxl1 ENSMUSG00000042548 0.408861338264557 0.930794506513674 0.710447901186555 0.930794506513674 0.930794506513674 0.930794506513674
Usp48 ENSMUSG00000043411 0.675576381154849 0.779281728953017 0.459996534139036 0.779281728953017 0.779281728953017 0.779281728953017
Yod1 ENSMUSG00000046404 0.159663361778729 0.477072661212058 0.477072661212058 0.477072661212058 0.388914696094678 0.477072661212058
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Tada3 ENSMUSG00000048930 0.445386787053696 0.668080180580543 0.127981844316683 0.383945532950048 0.893137831012048 0.893137831012048
Usp42 ENSMUSG00000051306 0.517173520468805 0.852835531331225 0.669841315712961 0.852835531331225 0.852835531331225 0.852835531331225
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Foxk1 ENSMUSG00000056493 0.90262961659103 0.971667329399804 0.971667329399804 0.971667329399804 0.912012543977666 0.971667329399804
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Mysm1 ENSMUSG00000062627 0.402165611878691 0.603248417818037 0.233701829303918 0.603248417818037 0.675609193134516 0.675609193134516
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074

RNA Polymerase II Transcription Elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Supt6 ENSMUSG00000002052 0.918249683822428 0.921384615446289 0.509525588181232 0.921384615446289 0.921384615446289 0.921384615446289
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Mllt1 ENSMUSG00000024212 0.974811565183814 0.974811565183814 0.543035961218538 0.974811565183814 0.837368583319366 0.974811565183814
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Iws1 ENSMUSG00000024384 0.613303748580275 0.613303748580275 0.469731250453748 0.613303748580275 0.59672817939277 0.613303748580275
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Formation of RNA Pol II elongation complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Supt6 ENSMUSG00000002052 0.918249683822428 0.921384615446289 0.509525588181232 0.921384615446289 0.921384615446289 0.921384615446289
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Mllt1 ENSMUSG00000024212 0.974811565183814 0.974811565183814 0.543035961218538 0.974811565183814 0.837368583319366 0.974811565183814
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Iws1 ENSMUSG00000024384 0.613303748580275 0.613303748580275 0.469731250453748 0.613303748580275 0.59672817939277 0.613303748580275
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

RNA Polymerase II Transcription Termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chtop ENSMUSG00000001017 0.561477316618918 0.842215974928376 0.241574688584194 0.724724065752581 0.952782373495003 0.952782373495003
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx39b ENSMUSG00000019432 0.413428017301453 0.540464241650657 0.540464241650657 0.540464241650657 0.519729291780184 0.540464241650657
Slu7 ENSMUSG00000020409 0.0949727328069262 0.255992391570273 0.170661594380182 0.255992391570273 0.846657984142829 0.846657984142829
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Srsf5 ENSMUSG00000021134 0.987403411477786 0.987403411477786 0.278457590927692 0.835372772783077 0.815871458314905 0.987403411477786
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Thoc1 ENSMUSG00000024287 0.661231129825359 0.859035646989233 0.287453707561746 0.859035646989233 0.859035646989233 0.859035646989233
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Thoc3 ENSMUSG00000025872 0.915135583169132 0.915135583169132 0.0300846532782823 0.090253959834847 0.887015274317648 0.915135583169132
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Srsf9 ENSMUSG00000029538 0.574909923893705 0.618766879077035 0.232134013336997 0.618766879077035 0.618766879077035 0.618766879077035
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
U2af2 ENSMUSG00000030435 0.31874830302137 0.478122454532055 0.264506638166949 0.478122454532055 0.550500704321653 0.550500704321653
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Rnps1 ENSMUSG00000034681 0.390891449270028 0.586337173905043 0.248026140061356 0.586337173905043 0.806560541744086 0.806560541744086
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Upf3b ENSMUSG00000036572 0.367530605753487 0.551295908630231 0.209577991938753 0.551295908630231 0.924538358347075 0.924538358347075
Thoc2 ENSMUSG00000037475 0.315218847953589 0.472828271930384 0.115476766292169 0.346430298876507 0.868328866876197 0.868328866876197
Dhx38 ENSMUSG00000037993 0.455231641312253 0.46973770964634 0.305726698076329 0.46973770964634 0.46973770964634 0.46973770964634
Rbm8a ENSMUSG00000038374 0.669841940395352 0.915125414031209 0.336673047366096 0.915125414031209 0.915125414031209 0.915125414031209
Cdc40 ENSMUSG00000038446 0.203881757854895 0.305822636782343 0.103110350475973 0.305822636782343 0.752157170215914 0.752157170215914
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Poldip3 ENSMUSG00000041815 0.151602808803964 0.378081041909176 0.378081041909176 0.378081041909176 0.300171361297585 0.378081041909176
Lsm11 ENSMUSG00000044847 0.436363548388505 0.654545322582758 0.219769748508287 0.654545322582758 0.692921430693931 0.692921430693931
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Srsf11 ENSMUSG00000055436 0.501863009786265 0.752794514679398 0.388721296902601 0.752794514679398 0.791400320535972 0.791400320535972
Srsf3 ENSMUSG00000071172 0.955939908876284 0.955939908876284 0.812805686687878 0.955939908876284 0.803632515765649 0.955939908876284
Casc3 ENSMUSG00000078676 0.834311834908601 0.993702598053241 0.915141586626199 0.993702598053241 0.993702598053241 0.993702598053241
U2af1l4 ENSMUSG00000078765 0.185512476091728 0.247428377338773 0.110988474246801 0.247428377338773 0.247428377338773 0.247428377338773

Transport of Mature mRNAs Derived from Intronless Transcripts

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Nucleotide Excision Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Usp45 ENSMUSG00000040455 0.427099674201283 0.981105959111385 0.868332276481305 0.981105959111385 0.981105959111385 0.981105959111385
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Xrcc1 ENSMUSG00000051768 0.373889676064885 0.560834514097327 0.311472140296653 0.560834514097327 0.782330754853731 0.782330754853731
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271

Transcriptional Regulation by TP53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Taco1 ENSMUSG00000001983 0.086484862945857 0.259454588837571 0.815861281163154 0.815861281163154 0.528925419338586 0.793388129007879
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Cdk12 ENSMUSG00000003119 0.755162148087285 0.93394600324458 0.67272885843545 0.93394600324458 0.93394600324458 0.93394600324458
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Ttc5 ENSMUSG00000006288 0.289245761101568 0.797531873832735 0.797531873832735 0.797531873832735 0.591266864698899 0.797531873832735
Hipk1 ENSMUSG00000008730 0.0940924963949365 0.28227748918481 0.713539120862588 0.713539120862588 0.684230035763789 0.713539120862588
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Surf1 ENSMUSG00000015790 0.440974576923634 0.661461865385452 0.666963880398388 0.666963880398388 0.422383519581425 0.661461865385452
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ddit4 ENSMUSG00000020108 0.00110456316369261 0.00331368949107784 0.427076652651413 0.640614978977119 0.821992898986527 0.821992898986527
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Cox11 ENSMUSG00000020544 0.0434338691683981 0.0651508037525971 1.83822333159272e-06 5.51466999477816e-06 0.324900544328719 0.324900544328719
Rffl ENSMUSG00000020696 0.499406497178666 0.569551782735742 0.309533365572562 0.569551782735742 0.569551782735742 0.569551782735742
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Ppp1r13b ENSMUSG00000021285 0.707638838245221 0.785353922376112 0.785353922376112 0.785353922376112 0.779270489867307 0.785353922376112
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Banp ENSMUSG00000025316 0.352973634799885 0.352973634799885 0.0550155669365745 0.165046700809724 0.313355013846564 0.352973634799885
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Gls ENSMUSG00000026103 0.862052724029941 0.993702533374486 0.981097390127074 0.993702533374486 0.993702533374486 0.993702533374486
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
G6pdx ENSMUSG00000031400 0.635393278727122 0.924487728862621 0.924487728862621 0.924487728862621 0.564262605828105 0.924487728862621
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Cox18 ENSMUSG00000035505 0.388966256857858 0.583449385286787 0.0631197324422958 0.189359197326887 0.770219768862008 0.770219768862008
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Rabggta ENSMUSG00000040472 0.110815597879801 0.332446793639402 0.344762181344561 0.41312505544048 0.41312505544048 0.41312505544048
Cdk13 ENSMUSG00000041297 0.350848580104832 0.89949118258729 0.788318112038651 0.89949118258729 0.89949118258729 0.89949118258729
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Zfp420 ENSMUSG00000058402 0.155023950321555 0.465071850964665 0.56424187734588 0.56424187734588 0.371750809395157 0.557626214092735
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932

Signaling by NTRKs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Nab2 ENSMUSG00000025402 0.499393542731024 0.974814176831575 0.707644882711197 0.974814176831575 0.974814176831575 0.974814176831575
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Ralgds ENSMUSG00000026821 0.812804004429882 0.812804004429882 0.583105102689558 0.812804004429882 0.543088585547914 0.812804004429882
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Egr2 ENSMUSG00000037868 0.48859656608548 0.573870218118701 0.552913061760835 0.573870218118701 0.573870218118701 0.573870218118701
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Ntf3 ENSMUSG00000049107 0.785026324408054 0.785026324408054 0.213873324120611 0.510449201721027 0.340299467814018 0.510449201721027
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624

Signaling by NTRK1 (TRKA)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Nab2 ENSMUSG00000025402 0.499393542731024 0.974814176831575 0.707644882711197 0.974814176831575 0.974814176831575 0.974814176831575
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Ralgds ENSMUSG00000026821 0.812804004429882 0.812804004429882 0.583105102689558 0.812804004429882 0.543088585547914 0.812804004429882
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Egr2 ENSMUSG00000037868 0.48859656608548 0.573870218118701 0.552913061760835 0.573870218118701 0.573870218118701 0.573870218118701
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624

Gene Silencing by RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Tarbp2 ENSMUSG00000023051 0.008972884631416 0.026918653894248 0.215388230370671 0.323082345556007 0.67841067518176 0.67841067518176
Tsn ENSMUSG00000026374 0.588541396682904 0.728316589011037 0.330792910053038 0.728316589011037 0.728316589011037 0.728316589011037
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Ago2 ENSMUSG00000036698 0.481894144503412 0.987402845972038 0.846656056497879 0.987402845972038 0.987402845972038 0.987402845972038
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Ipo8 ENSMUSG00000040029 0.481680727560799 0.737621428063108 0.491747618708739 0.737621428063108 0.809596030569435 0.809596030569435
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Ago1 ENSMUSG00000041530 0.924502000524229 0.924502000524229 0.918254215470046 0.924502000524229 0.740051340943326 0.924502000524229
Ago4 ENSMUSG00000042500 0.661114457350717 0.940210895276645 0.828130337550788 0.940210895276645 0.940210895276645 0.940210895276645
Tnrc6b ENSMUSG00000047888 0.746186023227431 0.746186023227431 0.704714294857786 0.746186023227431 0.64982873699181 0.746186023227431
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Tnrc6a ENSMUSG00000052707 0.843558416051339 0.843558416051339 0.408919705164051 0.843558416051339 0.773228059504463 0.843558416051339
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

M Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ncaph2 ENSMUSG00000008690 0.215376326001663 0.452963279876567 0.301975519917712 0.452963279876567 0.743096857325309 0.743096857325309
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Gorasp2 ENSMUSG00000014959 0.818845463937341 0.818845463937341 0.227420935877475 0.682262807632424 0.731224463471102 0.818845463937341
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Mau2 ENSMUSG00000031858 0.834298450887605 0.834298450887605 0.452868066498504 0.679302099747755 0.359166882511679 0.679302099747755
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mcph1 ENSMUSG00000039842 0.825032084599903 0.896355871343233 0.275019180028792 0.825057540086376 0.896355871343233 0.896355871343233
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Numa1 ENSMUSG00000066306 0.862112472143811 0.862112472143811 0.524888831496724 0.862112472143811 0.621580834430389 0.862112472143811
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

PI Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pnpla6 ENSMUSG00000004565 0.328721727659331 0.493082591488996 0.242715044767789 0.493082591488996 0.7134020315329 0.7134020315329
Inpp5k ENSMUSG00000006127 0.566857130340692 0.854429356932178 0.89010984134026 0.89010984134026 0.569619571288119 0.854429356932178
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr1 ENSMUSG00000015214 0.28209068750968 0.613378299339732 0.408918866226488 0.613378299339732 0.990553880737655 0.990553880737655
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Rufy1 ENSMUSG00000020375 0.740130266115853 0.949614807003285 0.669755040840901 0.949614807003285 0.949614807003285 0.949614807003285
Mtmr6 ENSMUSG00000021987 0.113641206247705 0.340923618743115 0.384520718380111 0.576781077570167 0.987405339532972 0.987405339532972
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Mtmr9 ENSMUSG00000035078 0.927673926601617 0.927673926601617 0.460088851731596 0.795020709426467 0.530013806284311 0.795020709426467
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965
Pi4kb ENSMUSG00000038861 0.785002570027176 0.809512890262261 0.519502292050506 0.809512890262261 0.809512890262261 0.809512890262261
Mtmr12 ENSMUSG00000039458 0.800578883012737 0.800578883012737 0.464902733669432 0.697354100504148 0.352960263597269 0.697354100504148
Plekha1 ENSMUSG00000040268 0.0565578015598726 0.169673404679618 0.41776716443371 0.516947777848175 0.516947777848175 0.516947777848175
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Plekha6 ENSMUSG00000041757 0.322936013292587 0.955938218410897 0.761148030256025 0.955938218410897 0.955938218410897 0.955938218410897
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Pitpnb ENSMUSG00000050017 0.66681478194078 0.874498115969145 0.311271826746177 0.874498115969145 0.874498115969145 0.874498115969145
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053

Metabolism of non-coding RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.127086859667951 0.190630289501926 0.0880298593793974 0.190630289501926 0.455295294594226 0.455295294594226
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Smn1 ENSMUSG00000021645 0.326871571824232 0.809722038047398 0.800560045965864 0.809722038047398 0.809722038047398 0.809722038047398
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ddx20 ENSMUSG00000027905 0.859038138942191 0.962224450626547 0.529990757346025 0.962224450626547 0.962224450626547 0.962224450626547
Tgs1 ENSMUSG00000028233 0.202445619281456 0.607336857844367 0.681406823438836 0.722389056632982 0.722389056632982 0.722389056632982
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Gemin5 ENSMUSG00000037275 0.35498753165118 0.53248129747677 0.0619870721452988 0.185961216435896 0.791428611405528 0.791428611405528
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Gemin8 ENSMUSG00000040621 0.256037057548284 0.768111172644851 0.588307079872917 0.882460619809375 0.899487888803449 0.899487888803449
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Gemin4 ENSMUSG00000049396 0.728280763310707 0.728280763310707 0.399829192861332 0.599743789291998 0.198256909157096 0.594770727471287
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Snupn ENSMUSG00000055334 0.448132247942238 0.752823647500484 0.50188243166699 0.752823647500484 0.9590809387123 0.9590809387123
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

snRNP Assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.127086859667951 0.190630289501926 0.0880298593793974 0.190630289501926 0.455295294594226 0.455295294594226
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Smn1 ENSMUSG00000021645 0.326871571824232 0.809722038047398 0.800560045965864 0.809722038047398 0.809722038047398 0.809722038047398
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ddx20 ENSMUSG00000027905 0.859038138942191 0.962224450626547 0.529990757346025 0.962224450626547 0.962224450626547 0.962224450626547
Tgs1 ENSMUSG00000028233 0.202445619281456 0.607336857844367 0.681406823438836 0.722389056632982 0.722389056632982 0.722389056632982
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Gemin5 ENSMUSG00000037275 0.35498753165118 0.53248129747677 0.0619870721452988 0.185961216435896 0.791428611405528 0.791428611405528
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Gemin8 ENSMUSG00000040621 0.256037057548284 0.768111172644851 0.588307079872917 0.882460619809375 0.899487888803449 0.899487888803449
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Gemin4 ENSMUSG00000049396 0.728280763310707 0.728280763310707 0.399829192861332 0.599743789291998 0.198256909157096 0.594770727471287
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Snupn ENSMUSG00000055334 0.448132247942238 0.752823647500484 0.50188243166699 0.752823647500484 0.9590809387123 0.9590809387123
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Cell Cycle, Mitotic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ncaph2 ENSMUSG00000008690 0.215376326001663 0.452963279876567 0.301975519917712 0.452963279876567 0.743096857325309 0.743096857325309
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Gorasp2 ENSMUSG00000014959 0.818845463937341 0.818845463937341 0.227420935877475 0.682262807632424 0.731224463471102 0.818845463937341
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Dyrk1a ENSMUSG00000022897 0.356444805291483 0.761099790833155 0.761099790833155 0.761099790833155 0.618254556879701 0.761099790833155
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Cdc7 ENSMUSG00000029283 0.905754675088245 0.937088160291987 0.937088160291987 0.937088160291987 0.758177847489751 0.937088160291987
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Mau2 ENSMUSG00000031858 0.834298450887605 0.834298450887605 0.452868066498504 0.679302099747755 0.359166882511679 0.679302099747755
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Fkbpl ENSMUSG00000033739 0.522200976154869 0.862104054739938 0.862104054739938 0.862104054739938 0.687192773503887 0.862104054739938
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Lin37 ENSMUSG00000036845 0.0665870101587646 0.0998805152381469 0.0175068864312451 0.0525206592937352 0.698862462776113 0.698862462776113
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mcph1 ENSMUSG00000039842 0.825032084599903 0.896355871343233 0.275019180028792 0.825057540086376 0.896355871343233 0.896355871343233
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Cables1 ENSMUSG00000040957 0.971663259417754 0.971663259417754 0.499395893797283 0.971663259417754 0.912003502782391 0.971663259417754
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Numa1 ENSMUSG00000066306 0.862112472143811 0.862112472143811 0.524888831496724 0.862112472143811 0.621580834430389 0.862112472143811
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

SUMOylation of ubiquitinylation proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Intra-Golgi and retrograde Golgi-to-ER traffic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Pafah1b3 ENSMUSG00000005447 0.429431168017631 0.687130134373971 0.687130134373971 0.687130134373971 0.627161792520192 0.687130134373971
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Kif19a ENSMUSG00000010021 0.707571700801429 0.809347792166954 0.754701535164911 0.809347792166954 0.809347792166954 0.809347792166954
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Vps53 ENSMUSG00000017288 0.377941116190403 0.566911674285605 0.0918141240913908 0.275442372274172 0.974802785331107 0.974802785331107
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Nbas ENSMUSG00000020576 0.831199458852206 0.831199458852206 0.0753846720564074 0.226154016169222 0.247920106909697 0.371880160364545
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Bnip1 ENSMUSG00000024191 0.0346582671987526 0.0709621643207598 0.0473081095471732 0.0709621643207598 0.489381298258457 0.489381298258457
Vps52 ENSMUSG00000024319 0.621367928119512 0.788281082479196 0.357097229975649 0.788281082479196 0.788281082479196 0.788281082479196
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Vps51 ENSMUSG00000024797 0.105653507029143 0.310135981870419 0.206757321246946 0.310135981870419 0.38454930818886 0.38454930818886
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Golga1 ENSMUSG00000026754 0.211073540781294 0.316610311171941 0.158430081793005 0.316610311171941 0.43174020429507 0.43174020429507
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Rint1 ENSMUSG00000028999 0.937073603772649 0.937073603772649 0.422451096973321 0.937073603772649 0.852843783462489 0.937073603772649
Stx18 ENSMUSG00000029125 0.309581512482546 0.737857261122885 0.927674707753686 0.927674707753686 0.49190484074859 0.737857261122885
Gcc1 ENSMUSG00000029708 0.464741208485198 0.698842272802265 0.698842272802265 0.698842272802265 0.613122438466004 0.698842272802265
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Tmf1 ENSMUSG00000030059 0.0268244330294316 0.080473299088295 0.469722256882648 0.704583385323973 0.946493484550472 0.946493484550472
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Arfip2 ENSMUSG00000030881 0.968488970040684 0.968488970040684 0.672464777544939 0.968488970040684 0.655477247667167 0.968488970040684
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Kif9 ENSMUSG00000032489 0.852651985562056 0.95277494340192 0.95277494340192 0.95277494340192 0.893051561758697 0.95277494340192
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Bicd2 ENSMUSG00000037933 0.188558410070277 0.422937960694121 0.281958640462747 0.422937960694121 0.692946871935085 0.692946871935085
Arfrp1 ENSMUSG00000038671 0.320994413286289 0.481491619929434 0.122042650948381 0.366127952845144 0.749059059663526 0.749059059663526
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Sys1 ENSMUSG00000045503 0.0152643007233324 0.0228964510849985 0.00330599018088915 0.00991797054266744 0.821986076879709 0.821986076879709
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Kif13b ENSMUSG00000060012 0.825065979446263 0.825065979446263 0.758155212029761 0.825065979446263 0.649810810611423 0.825065979446263
Kif27 ENSMUSG00000060176 0.90794064172691 0.974602699673214 0.583115579423678 0.974602699673214 0.974602699673214 0.974602699673214
Arl1 ENSMUSG00000060904 0.977954922786188 0.977954922786188 0.883883578019259 0.977954922786188 0.369504346512649 0.977954922786188
Rabepk ENSMUSG00000070953 0.230468444889404 0.345702667334107 0.113689596861401 0.341068790584202 0.49433381603067 0.49433381603067
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298

RNA Polymerase I Promoter Clearance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Rrn3 ENSMUSG00000022682 0.624339904317712 0.834266910855487 0.344792065919548 0.834266910855487 0.834266910855487 0.834266910855487
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

SUMOylation of DNA replication proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Top2b ENSMUSG00000017485 0.621570154742956 0.970443928900233 0.646962619266822 0.970443928900233 0.977954326966792 0.977954326966792
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Top1 ENSMUSG00000070544 0.0524875749189175 0.157462724756753 0.865185136694549 0.981099842312976 0.981099842312976 0.981099842312976

RNA Polymerase I Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Rrn3 ENSMUSG00000022682 0.624339904317712 0.834266910855487 0.344792065919548 0.834266910855487 0.834266910855487 0.834266910855487
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

SUMOylation of transcription cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Uhrf2 ENSMUSG00000024817 0.915142256744398 0.915142256744398 0.649828919527377 0.915142256744398 0.550973357034918 0.915142256744398
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Park7 ENSMUSG00000028964 0.100193509532914 0.300580528598743 0.340072180267643 0.501892715742569 0.501892715742569 0.501892715742569
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Ddx17 ENSMUSG00000055065 0.828152914507463 0.871447107023116 0.871447107023116 0.871447107023116 0.489429050732231 0.871447107023116
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Safb ENSMUSG00000071054 0.574823745567258 0.883875670750215 0.825027507382374 0.883875670750215 0.883875670750215 0.883875670750215
Zfp131 ENSMUSG00000094870 0.201075240296991 0.464329328589451 0.3095528857263 0.464329328589451 0.621633089534301 0.621633089534301

RNA Polymerase I Transcription Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Rrn3 ENSMUSG00000022682 0.624339904317712 0.834266910855487 0.344792065919548 0.834266910855487 0.834266910855487 0.834266910855487
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

Transcriptional regulation by small RNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Ago2 ENSMUSG00000036698 0.481894144503412 0.987402845972038 0.846656056497879 0.987402845972038 0.987402845972038 0.987402845972038
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Ipo8 ENSMUSG00000040029 0.481680727560799 0.737621428063108 0.491747618708739 0.737621428063108 0.809596030569435 0.809596030569435
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Tnrc6a ENSMUSG00000052707 0.843558416051339 0.843558416051339 0.408919705164051 0.843558416051339 0.773228059504463 0.843558416051339
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Deadenylation-dependent mRNA decay

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Nt5c3b ENSMUSG00000017176 0.840372799791322 0.840393572668707 0.840393572668707 0.840393572668707 0.716475716566378 0.840393572668707
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Eif4a2 ENSMUSG00000022884 0.776262606175218 0.794463575615136 0.509527671271441 0.794463575615136 0.794463575615136 0.794463575615136
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Pan3 ENSMUSG00000029647 0.655456393746432 0.849722654511013 0.524801691324984 0.849722654511013 0.849722654511013 0.849722654511013
Ddx6 ENSMUSG00000032097 0.404397194234859 0.752177062517396 0.752177062517396 0.752177062517396 0.652647416539278 0.752177062517396
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Ttc37 ENSMUSG00000033991 0.209479265727045 0.314218898590567 0.161957506810136 0.314218898590567 0.602092125220025 0.602092125220025
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Zcchc11 ENSMUSG00000034610 0.871429201699317 0.927668208119842 0.448129353121277 0.927668208119842 0.927668208119842 0.927668208119842
Lsm7 ENSMUSG00000035215 0.454768207938296 0.682152311907443 0.74018145342406 0.74018145342406 0.433277878640342 0.682152311907443
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Edc3 ENSMUSG00000038957 0.296508606448352 0.590017516235972 0.393345010823981 0.590017516235972 0.701792729756973 0.701792729756973
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388
Skiv2l ENSMUSG00000040356 0.320818972045176 0.481228458067763 0.303842486320552 0.481228458067763 0.812719792582066 0.812719792582066
Dcp1b ENSMUSG00000041477 0.737228299731999 0.955937196174637 0.556281929705088 0.955937196174637 0.955937196174637 0.955937196174637
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Patl1 ENSMUSG00000046139 0.393283354429965 0.633716138428704 0.422477425619136 0.633716138428704 0.971664088103294 0.971664088103294
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245

TP53 Regulates Transcription of DNA Repair Genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Cdk12 ENSMUSG00000003119 0.755162148087285 0.93394600324458 0.67272885843545 0.93394600324458 0.93394600324458 0.93394600324458
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ccnt2 ENSMUSG00000026349 0.462466455093017 0.545684775031045 0.420244663235443 0.545684775031045 0.545684775031045 0.545684775031045
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cdk13 ENSMUSG00000041297 0.350848580104832 0.89949118258729 0.788318112038651 0.89949118258729 0.89949118258729 0.89949118258729
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ell ENSMUSG00000070002 0.825071053326326 0.825071053326326 0.494266136585382 0.825071053326326 0.80662832598225 0.825071053326326
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

SUMOylation of SUMOylation proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Transport of the SLBP independent Mature mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Class I MHC mediated antigen processing & presentation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Fbxo9 ENSMUSG00000001366 0.213593913192257 0.460696954000312 0.307131302666875 0.460696954000312 0.940194121838634 0.940194121838634
Npepps ENSMUSG00000001441 0.828113611642018 0.952784933693202 0.464917315303708 0.952784933693202 0.952784933693202 0.952784933693202
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Fbxo11 ENSMUSG00000005371 0.229006001463732 0.687018004391197 0.610471723108175 0.915707584662263 0.933935404170617 0.933935404170617
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Fbxw5 ENSMUSG00000015095 0.312266225489717 0.583363918635638 0.388909279090426 0.583363918635638 0.818437948865218 0.818437948865218
Unkl ENSMUSG00000015127 0.996851177572851 0.996851177572851 0.545614747144691 0.894995396130751 0.596663597420501 0.894995396130751
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Wsb1 ENSMUSG00000017677 0.692964035503656 0.767165274931203 0.621531949939947 0.767165274931203 0.767165274931203 0.767165274931203
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Cbll1 ENSMUSG00000020659 0.332798912996212 0.927673693056393 0.927673693056393 0.927673693056393 0.72535227553832 0.927673693056393
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Fbxl20 ENSMUSG00000020883 0.443360548542608 0.72231253977434 0.599400170065276 0.72231253977434 0.72231253977434 0.72231253977434
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Mgrn1 ENSMUSG00000022517 0.305815061085114 0.458722591627671 0.118351209981931 0.355053629945794 0.514627522318353 0.514627522318353
Cblb ENSMUSG00000022637 0.746155443398164 0.899473090695014 0.899473090695014 0.899473090695014 0.652564273701327 0.899473090695014
Lnpep ENSMUSG00000023845 0.0378778232870052 0.113633469861016 0.269723274511539 0.404584911767309 0.880750693978909 0.880750693978909
Ubr2 ENSMUSG00000023977 0.728321543444688 0.728321543444688 0.610514851941879 0.728321543444688 0.704723379510603 0.728321543444688
Rnf138 ENSMUSG00000024317 0.629945031930056 0.944917547895085 0.413388290114401 0.944917547895085 1 1
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Fbxl15 ENSMUSG00000025226 0.307695222968975 0.461542834453462 0.00805888483641587 0.0241766545092476 0.859033170480059 0.859033170480059
Huwe1 ENSMUSG00000025261 0.669851622519722 0.962228686136411 0.962228686136411 0.962228686136411 0.604992885090226 0.962228686136411
Ube3a ENSMUSG00000025326 0.0100021217833753 0.030006365350126 0.0964484346882663 0.144672652032399 0.522158709680698 0.522158709680698
Rnf41 ENSMUSG00000025373 0.918271852600076 0.918271852600076 0.825079431949656 0.918271852600076 0.716480625543547 0.918271852600076
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Rnf25 ENSMUSG00000026171 0.722329734065528 0.981104486388196 0.687145764567564 0.981104486388196 0.981104486388196 0.981104486388196
Trip12 ENSMUSG00000026219 0.31527763384103 0.707623507301317 0.594013590497052 0.707623507301317 0.707623507301317 0.707623507301317
Asb1 ENSMUSG00000026311 0.601944165244773 0.601944165244773 0.0636532260572407 0.190959678171722 0.454867103954538 0.601944165244773
Klhl20 ENSMUSG00000026705 0.519684141499169 0.695920118882848 0.496896837138848 0.695920118882848 0.695920118882848 0.695920118882848
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Ubr1 ENSMUSG00000027272 0.469759818197924 0.580387749709864 0.530051937757425 0.580387749709864 0.580387749709864 0.580387749709864
Ubox5 ENSMUSG00000027300 0.289246626019819 0.433869939029728 0.752174358730662 0.752174358730662 0.170623956292642 0.433869939029728
Rbck1 ENSMUSG00000027466 0.26432804499609 0.646757686737436 0.646757686737436 0.646757686737436 0.504183875642183 0.646757686737436
Ube2j1 ENSMUSG00000028277 0.472189545060989 0.96851806962253 0.96851806962253 0.96851806962253 0.719407192774666 0.96851806962253
Rnf220 ENSMUSG00000028677 0.566892123333099 0.850338184999648 0.479520836960388 0.850338184999648 0.959081732985053 0.959081732985053
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Mib2 ENSMUSG00000029060 0.450479828987673 0.675719743481509 0.236789471977911 0.675719743481509 0.704639605500424 0.704639605500424
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Glmn ENSMUSG00000029276 0.616066355828508 0.669836942837089 0.369647542185504 0.669836942837089 0.669836942837089 0.669836942837089
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Rnf6 ENSMUSG00000029634 0.0149513282232087 0.0448539846696261 0.0603000662838841 0.0904500994258261 0.846617386793513 0.846617386793513
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Mkrn1 ENSMUSG00000029922 0.216490221537255 0.324735332305882 0.118244827676101 0.324735332305882 0.61016482119888 0.61016482119888
Fbxl14 ENSMUSG00000030019 0.585733426897513 0.878600140346269 0.296343958092929 0.878600140346269 0.912009716457441 0.912009716457441
Kbtbd8 ENSMUSG00000030031 0.566939894440354 0.737225190462243 0.737225190462243 0.737225190462243 0.707644415368941 0.737225190462243
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Asb7 ENSMUSG00000030509 0.886996648412827 0.886996648412827 0.722376332987625 0.886996648412827 0.855908935982981 0.886996648412827
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Rbbp6 ENSMUSG00000030779 0.831182834902999 0.831182834902999 0.764140628139708 0.831182834902999 0.758082080951701 0.831182834902999
Stx4a ENSMUSG00000030805 0.583114701383756 0.583114701383756 0.545715758505275 0.583114701383756 0.535245520817248 0.583114701383756
Fbxl19 ENSMUSG00000030811 0.859032111304213 0.859032111304213 0.624401770964706 0.859032111304213 0.821993934939889 0.859032111304213
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Ube2cbp ENSMUSG00000032415 0.246222587997866 0.545451973176 0.472046787651495 0.545451973176 0.545451973176 0.545451973176
Uba5 ENSMUSG00000032557 0.21245362762891 0.637360882886731 0.675607997039037 0.965372819853871 0.965372819853871 0.965372819853871
Traip ENSMUSG00000032586 0.415002383672552 0.625690789604884 0.417127193069923 0.625690789604884 0.739816268845056 0.739816268845056
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Trim36 ENSMUSG00000033949 0.981107319702807 0.981107319702807 0.949644952980045 0.981107319702807 0.828122608330827 0.981107319702807
Hectd1 ENSMUSG00000035247 0.0506398787063026 0.151919636118908 0.996848007433573 0.996848007433573 0.157356304443767 0.23603445666565
Rnf126 ENSMUSG00000035890 0.886883315975953 0.886883315975953 0.767054704087373 0.886883315975953 0.276331251365775 0.828993754097326
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Siah1a ENSMUSG00000036840 0.713481603401334 0.766960237832609 0.601996199580706 0.766960237832609 0.766960237832609 0.766960237832609
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Mex3c ENSMUSG00000037253 0.553615741912637 0.818915481821514 0.818915481821514 0.818915481821514 0.701727917939143 0.818915481821514
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Herc1 ENSMUSG00000038664 0.26109821284758 0.783294638542741 0.734165220730748 0.843515288270164 0.843515288270164 0.843515288270164
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Hace1 ENSMUSG00000038822 0.773234390624075 0.773234390624075 0.282065707839971 0.773234390624075 0.770225804325364 0.773234390624075
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Asb6 ENSMUSG00000039483 0.918255734950225 0.918255734950225 0.862104557997622 0.918255734950225 0.692981424119149 0.918255734950225
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Fbxl5 ENSMUSG00000039753 0.460089905660059 0.527349966742554 0.382374381325839 0.527349966742554 0.527349966742554 0.527349966742554
Spsb1 ENSMUSG00000039911 0.319080089631295 0.580187025826347 0.865240833296443 0.865240833296443 0.386791350550898 0.580187025826347
Klhl42 ENSMUSG00000040102 0.472026108099081 0.868301215980349 0.868301215980349 0.868301215980349 0.776168664106968 0.868301215980349
Vprbp ENSMUSG00000040325 0.408731381241263 0.613097071861894 0.159571603950442 0.478714811851326 0.981095497003617 0.981095497003617
Ufl1 ENSMUSG00000040359 0.00154014050357583 0.00231021075536375 0.000299240768687186 0.000897722306061557 0.666816357599575 0.666816357599575
Trim41 ENSMUSG00000040365 0.599413027950627 0.952785966083281 0.952785966083281 0.952785966083281 0.862125948978978 0.952785966083281
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Fbxw4 ENSMUSG00000040913 0.0822124854277177 0.224008023834634 0.149338682556422 0.224008023834634 0.707633447761154 0.707633447761154
Wwp1 ENSMUSG00000041058 0.241489491015698 0.724468473047093 0.91826132991022 0.924534880356959 0.924534880356959 0.924534880356959
Tpp2 ENSMUSG00000041763 0.00435896654734185 0.0130768996420256 0.4745482659838 0.4745482659838 0.330764465635496 0.4745482659838
Arel1 ENSMUSG00000042350 0.776265111300032 0.776265111300032 0.424780757679406 0.675781994624233 0.450521329749489 0.675781994624233
Ube2q1 ENSMUSG00000042572 0.59923306870678 0.874455317143018 0.450530094906324 0.874455317143018 0.874455317143018 0.874455317143018
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Ltn1 ENSMUSG00000052299 0.436301373539077 0.846653790576662 0.767182147528682 0.846653790576662 0.846653790576662 0.846653790576662
Gan ENSMUSG00000052557 0.313344114171842 0.470016171257763 0.26299500485965 0.470016171257763 0.681391720765928 0.681391720765928
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Klhl5 ENSMUSG00000054920 0.441023563137958 0.556142046462253 0.540328093857368 0.556142046462253 0.556142046462253 0.556142046462253
Fbxo6 ENSMUSG00000055401 0.165725488149896 0.344494721839957 0.307467389409342 0.344494721839957 0.344494721839957 0.344494721839957
Klhl25 ENSMUSG00000055652 0.0531566348600952 0.159469904580285 0.219797201332521 0.329695801998782 0.342050703942181 0.342050703942181
Rlim ENSMUSG00000056537 0.170643280526332 0.350498044647242 0.233665363098161 0.350498044647242 0.937084234672894 0.937084234672894
Ube4a ENSMUSG00000059890 0.0880020106174511 0.264006031852353 0.930788868983936 0.930788868983936 0.340650207372243 0.510975311058364
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Arih2 ENSMUSG00000064145 0.231992720716999 0.347989081075498 0.129045338495288 0.347989081075498 0.782209240815231 0.782209240815231
Ubr4 ENSMUSG00000066036 0.911955765287219 0.911955765287219 0.752169941463026 0.911955765287219 0.73707734465406 0.911955765287219
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Fbxl12 ENSMUSG00000066892 0.514569590928347 0.771854386392521 0.968518283937401 0.968518283937401 0.404276434285822 0.771854386392521
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Ube2v1 ENSMUSG00000078923 0.707651456421661 0.707651456421661 0.0690119256001669 0.207035776800501 0.649779661098828 0.707651456421661
Fbxw10 ENSMUSG00000090173 0.74415417304833 0.74415417304833 0.635518344743522 0.74415417304833 0.729025476397157 0.74415417304833
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Formation of Incision Complex in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Usp45 ENSMUSG00000040455 0.427099674201283 0.981105959111385 0.868332276481305 0.981105959111385 0.981105959111385 0.981105959111385
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271

Phospholipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pla1a ENSMUSG00000002847 0.858985904894286 0.943339660366733 0.943339660366733 0.943339660366733 0.678302097204806 0.943339660366733
Pnpla6 ENSMUSG00000004565 0.328721727659331 0.493082591488996 0.242715044767789 0.493082591488996 0.7134020315329 0.7134020315329
Inpp5k ENSMUSG00000006127 0.566857130340692 0.854429356932178 0.89010984134026 0.89010984134026 0.569619571288119 0.854429356932178
Taz ENSMUSG00000009995 0.050568810778851 0.151706432336553 0.350844856540626 0.397745380880109 0.397745380880109 0.397745380880109
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr1 ENSMUSG00000015214 0.28209068750968 0.613378299339732 0.408918866226488 0.613378299339732 0.990553880737655 0.990553880737655
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Rufy1 ENSMUSG00000020375 0.740130266115853 0.949614807003285 0.669755040840901 0.949614807003285 0.949614807003285 0.949614807003285
Pld2 ENSMUSG00000020828 0.399889041502755 0.50445730348406 0.501888219526619 0.50445730348406 0.50445730348406 0.50445730348406
Lpcat1 ENSMUSG00000021608 0.484463417432125 0.484463417432125 0.25128699156916 0.484463417432125 0.469752465544028 0.484463417432125
Mtmr6 ENSMUSG00000021987 0.113641206247705 0.340923618743115 0.384520718380111 0.576781077570167 0.987405339532972 0.987405339532972
Agpat4 ENSMUSG00000023827 0.580376959010968 0.580376959010968 0.259547477740451 0.467077979851395 0.31138531990093 0.467077979851395
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Pitpnm1 ENSMUSG00000024851 0.477082320108226 0.704696688993702 0.658372352556585 0.704696688993702 0.704696688993702 0.704696688993702
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Ptdss2 ENSMUSG00000025495 0.574481726274386 0.574481726274386 0.0459589726116633 0.13787691783499 0.561089325177004 0.574481726274386
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Lpgat1 ENSMUSG00000026623 0.52712305525966 0.927622887535284 0.868316085785512 0.927622887535284 0.927622887535284 0.927622887535284
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Gpd2 ENSMUSG00000026827 0.770211837240975 0.940220286237586 0.607726703074384 0.940220286237586 0.940220286237586 0.940220286237586
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Lpcat4 ENSMUSG00000027134 0.899501162449904 0.968519369497954 0.924540298755749 0.968519369497954 0.968519369497954 0.968519369497954
Crls1 ENSMUSG00000027357 0.203902734612843 0.611708203838528 0.834301386897397 0.834301386897397 0.635642791570333 0.834301386897397
Stard7 ENSMUSG00000027367 0.00154647132929682 0.00231970699394523 0.000196740025591645 0.000590220076774934 0.273113182704102 0.273113182704102
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Slc44a1 ENSMUSG00000028412 0.815866632455274 0.815866632455274 0.509493249568485 0.764239874352727 0.415643682473567 0.764239874352727
Cds1 ENSMUSG00000029330 0.825077241324923 0.852832655754643 0.852832655754643 0.852832655754643 0.831219326851047 0.852832655754643
Etnk1 ENSMUSG00000030275 0.95592624690547 0.95592624690547 0.375943844636861 0.95592624690547 0.758123197522832 0.95592624690547
Cdipt ENSMUSG00000030682 0.632599618115493 0.632599618115493 0.0957536977912475 0.287261093373743 0.393067572338565 0.589601358507848
Dgat2 ENSMUSG00000030747 0.30953808308503 0.429185835061303 0.191317455322505 0.429185835061303 0.429185835061303 0.429185835061303
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pla2g15 ENSMUSG00000031903 0.196747826323332 0.295121739484998 0.15254254211582 0.295121739484998 0.602228479811121 0.602228479811121
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Lpcat2 ENSMUSG00000033192 0.690043714458379 0.690043714458379 0.566737170887083 0.690043714458379 0.30191632312261 0.690043714458379
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Pla2g4b ENSMUSG00000033852 0.527444602289874 0.716461169952855 0.716461169952855 0.716461169952855 0.564211955209473 0.716461169952855
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Mtmr9 ENSMUSG00000035078 0.927673926601617 0.927673926601617 0.460088851731596 0.795020709426467 0.530013806284311 0.795020709426467
Mboat7 ENSMUSG00000035596 0.918269279145594 0.943367638512925 0.743178985363091 0.943367638512925 0.943367638512925 0.943367638512925
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Osbpl5 ENSMUSG00000037606 0.131106474080707 0.393319422242121 0.666929011858287 0.737197965508037 0.737197965508037 0.737197965508037
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965
Pi4kb ENSMUSG00000038861 0.785002570027176 0.809512890262261 0.519502292050506 0.809512890262261 0.809512890262261 0.809512890262261
Mtmr12 ENSMUSG00000039458 0.800578883012737 0.800578883012737 0.464902733669432 0.697354100504148 0.352960263597269 0.697354100504148
Plekha1 ENSMUSG00000040268 0.0565578015598726 0.169673404679618 0.41776716443371 0.516947777848175 0.516947777848175 0.516947777848175
Cept1 ENSMUSG00000040774 0.013199221641137 0.0395976649234111 0.0336032486880714 0.0504048730321071 0.877623786997615 0.877623786997615
Osbpl10 ENSMUSG00000040875 0.883900970901229 0.883900970901229 0.874547971813779 0.883900970901229 0.692977223768889 0.883900970901229
Abhd4 ENSMUSG00000040997 0.452846375309222 0.452846375309222 0.0800809144602908 0.240242743380872 0.302070303160046 0.452846375309222
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Plekha6 ENSMUSG00000041757 0.322936013292587 0.955938218410897 0.761148030256025 0.955938218410897 0.955938218410897 0.955938218410897
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Pitpnb ENSMUSG00000050017 0.66681478194078 0.874498115969145 0.311271826746177 0.874498115969145 0.874498115969145 0.874498115969145
Gpd1l ENSMUSG00000050627 0.968508090352874 0.968508090352874 0.8745646837132 0.968508090352874 0.791353022004223 0.968508090352874
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Hadhb ENSMUSG00000059447 0.330599474432823 0.573202962671004 0.382135308447336 0.573202962671004 0.782302125834741 0.782302125834741
Chpt1 ENSMUSG00000060002 0.865242889840744 0.927670415131274 0.448134380939566 0.927670415131274 0.927670415131274 0.927670415131274
Ddhd2 ENSMUSG00000061313 0.743195451334068 0.743195451334068 0.627235811753331 0.743195451334068 0.610514453035679 0.743195451334068
Cpne1 ENSMUSG00000074643 0.300073874130076 0.627171956891319 0.566929578599647 0.627171956891319 0.627171956891319 0.627171956891319
Ept1 ENSMUSG00000075703 0.285485700861786 0.856457102585359 0.899482015015846 0.899482015015846 0.840434267513807 0.899482015015846

RNA Polymerase II Promoter Escape

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

RNA Polymerase II Transcription Initiation And Promoter Clearance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

RNA Polymerase II Transcription Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Gtf2e1 ENSMUSG00000022828 0.504464023823269 0.794455159477966 0.553589006851082 0.794455159477966 0.794455159477966 0.794455159477966
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Gtf2e2 ENSMUSG00000031585 0.561494257768437 0.794421551956259 0.527454390547849 0.794421551956259 0.794421551956259 0.794421551956259
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Transport of the SLBP Dependant Mature mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nxf1 ENSMUSG00000010097 0.962221056976288 0.962221056976288 0.880767470654617 0.962221056976288 0.803625599142682 0.962221056976288
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Cellular responses to stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Itfg2 ENSMUSG00000001518 0.285627844823271 0.511168106935029 0.340778737956686 0.511168106935029 0.722399668243088 0.722399668243088
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Atp6v1f ENSMUSG00000004285 0.0690338633958723 0.207101590187617 0.222939063628633 0.33440859544295 0.496913393196454 0.496913393196454
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Txn2 ENSMUSG00000005354 0.0964782040204012 0.144717306030602 0.0434143896562025 0.130243168968607 0.243191665062254 0.243191665062254
Dnajb1 ENSMUSG00000005483 0.0586319192556633 0.17589575776699 0.365224250049953 0.547836375074929 0.918239798940416 0.918239798940416
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Atp6v0d1 ENSMUSG00000013160 0.309561343978414 0.46434201596762 0.104014014296183 0.312042042888548 0.840455578977424 0.840455578977424
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Dnajc7 ENSMUSG00000014195 0.86204782294864 0.86204782294864 0.545717554455601 0.86204782294864 0.655272326469404 0.86204782294864
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Arnt ENSMUSG00000015522 0.737068311927084 0.911987634815449 0.834214517176173 0.911987634815449 0.911987634815449 0.911987634815449
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Kdm6b ENSMUSG00000018476 0.484195545231719 0.626973949023456 0.413265451928212 0.626973949023456 0.626973949023456 0.626973949023456
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Cabin1 ENSMUSG00000020196 0.435937778483662 0.9685027681816 0.949631362231867 0.9685027681816 0.9685027681816 0.9685027681816
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Nprl3 ENSMUSG00000020289 0.203702664069119 0.611107992207356 0.722382308562153 0.722382308562153 0.675532889963341 0.722382308562153
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Mink1 ENSMUSG00000020827 0.649824575103585 0.868347543600674 0.868347543600674 0.868347543600674 0.690113908065094 0.868347543600674
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ero1l ENSMUSG00000021831 0.271532657293146 0.779263764807282 0.779263764807282 0.779263764807282 0.704676658498023 0.779263764807282
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
St13 ENSMUSG00000022403 0.0226590047737139 0.0679770143211418 0.604803815022533 0.896293316948781 0.896293316948781 0.896293316948781
Hsf1 ENSMUSG00000022556 0.990550908712948 0.990550908712948 0.330808024830752 0.990550908712948 0.855851704034247 0.990550908712948
Hira ENSMUSG00000022702 0.886996121840201 0.886996121840201 0.635615261017125 0.886996121840201 0.880766082782286 0.886996121840201
Ets2 ENSMUSG00000022895 0.902614134126358 0.965370466591231 0.128069196665605 0.384207589996814 0.965370466591231 0.965370466591231
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Hspa9 ENSMUSG00000024359 0.874372392628939 0.874372392628939 0.130956750318228 0.392870250954683 0.692572140526636 0.874372392628939
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Prdx3 ENSMUSG00000024997 0.672673674526661 0.672673674526661 0.514604671968294 0.672673674526661 0.479486628055555 0.672673674526661
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Wdr24 ENSMUSG00000025737 0.0413116303984237 0.123934891195271 0.32483174034334 0.32483174034334 0.21534725888783 0.323020888331744
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Dnajb6 ENSMUSG00000029131 0.219922417387641 0.659767252162924 0.572241105334608 0.785322790404261 0.785322790404261 0.785322790404261
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ep400 ENSMUSG00000029505 0.489403160139127 0.678508023538091 0.678508023538091 0.678508023538091 0.545682664333404 0.678508023538091
Pot1a ENSMUSG00000029676 0.632850922486848 0.632850922486848 0.504454253028015 0.632850922486848 0.569575432520929 0.632850922486848
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Bag3 ENSMUSG00000030847 0.367173382225697 0.758025819441381 0.658276336671019 0.758025819441381 0.758025819441381 0.758025819441381
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Terf2 ENSMUSG00000031921 0.773244268082692 0.952795428259095 0.899501396840473 0.952795428259095 0.952795428259095 0.952795428259095
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Flcn ENSMUSG00000032633 0.276517143972942 0.414775715959413 0.0997574634578557 0.299272390373567 0.834211485220143 0.834211485220143
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Szt2 ENSMUSG00000033253 0.247980080472639 0.743940241417916 0.968517890437885 0.968517890437885 0.501934467396805 0.752901701095207
Atp6v0b ENSMUSG00000033379 0.241222590971426 0.361833886457138 0.110098072216306 0.330294216648917 0.534927117587497 0.534927117587497
Ccar2 ENSMUSG00000033712 0.336634005703503 0.758083338329465 0.52226328495119 0.758083338329465 0.758083338329465 0.758083338329465
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Sh3bp4 ENSMUSG00000036206 0.728324311980814 0.728324311980814 0.380299381820909 0.728324311980814 0.532628101354366 0.728324311980814
Wtip ENSMUSG00000036459 0.0293607558774252 0.0880822676322757 0.883849026562423 0.883849026562423 0.504113347161587 0.75617002074238
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Bag4 ENSMUSG00000037316 0.621603866745242 0.800562400888593 0.794449144111913 0.800562400888593 0.800562400888593 0.800562400888593
Depdc5 ENSMUSG00000037426 0.887011276666238 0.887011276666238 0.450420881006587 0.887011276666238 0.828115067084511 0.887011276666238
Acd ENSMUSG00000038000 0.367503836873599 0.620144848380297 0.413429898920198 0.620144848380297 0.849744691475226 0.849744691475226
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Ubn1 ENSMUSG00000039473 0.577570541594651 0.96222021369151 0.707655755575611 0.96222021369151 0.96222021369151 0.96222021369151
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cited2 ENSMUSG00000039910 0.296426512311656 0.296426512311656 0.236651113528526 0.296426512311656 0.261261147442375 0.296426512311656
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Hspb8 ENSMUSG00000041548 0.812800065306927 0.812800065306927 0.3509099291417 0.812800065306927 0.755176388819689 0.812800065306927
Mios ENSMUSG00000042447 0.794425526450263 0.987402692625264 0.566935300080862 0.987402692625264 0.987402692625264 0.987402692625264
B630005N14Rik ENSMUSG00000042742 0.707658154296541 0.740198014957057 0.740198014957057 0.740198014957057 0.704685054821577 0.740198014957057
Hmga1 ENSMUSG00000046711 0.737218293142865 0.7762549200246 0.457684286080448 0.7762549200246 0.7762549200246 0.7762549200246
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Rps19bp1 ENSMUSG00000051518 0.316936700314695 0.316936700314695 0.110795756493675 0.316936700314695 0.26299484426459 0.316936700314695
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
BC048403 ENSMUSG00000053684 0.666965593816086 0.930812612865626 0.402201800017423 0.930812612865626 0.930812612865626 0.930812612865626
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Egln2 ENSMUSG00000058709 0.419585870973821 0.629378806460731 0.302033889838096 0.629378806460731 0.940131257795237 0.940131257795237
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Ptges3 ENSMUSG00000071072 0.794466403205246 0.794466403205246 0.0539401077163417 0.161820323149025 0.596673651918825 0.794466403205246
Map3k5 ENSMUSG00000071369 0.946505334041831 0.946505334041831 0.464790285810797 0.946505334041831 0.883889101846502 0.946505334041831
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

COPI-mediated anterograde transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902

Cellular response to heat stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dnajb1 ENSMUSG00000005483 0.0586319192556633 0.17589575776699 0.365224250049953 0.547836375074929 0.918239798940416 0.918239798940416
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Dnajc7 ENSMUSG00000014195 0.86204782294864 0.86204782294864 0.545717554455601 0.86204782294864 0.655272326469404 0.86204782294864
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
St13 ENSMUSG00000022403 0.0226590047737139 0.0679770143211418 0.604803815022533 0.896293316948781 0.896293316948781 0.896293316948781
Hsf1 ENSMUSG00000022556 0.990550908712948 0.990550908712948 0.330808024830752 0.990550908712948 0.855851704034247 0.990550908712948
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Hspa9 ENSMUSG00000024359 0.874372392628939 0.874372392628939 0.130956750318228 0.392870250954683 0.692572140526636 0.874372392628939
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Dnajb6 ENSMUSG00000029131 0.219922417387641 0.659767252162924 0.572241105334608 0.785322790404261 0.785322790404261 0.785322790404261
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Bag3 ENSMUSG00000030847 0.367173382225697 0.758025819441381 0.658276336671019 0.758025819441381 0.758025819441381 0.758025819441381
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Ccar2 ENSMUSG00000033712 0.336634005703503 0.758083338329465 0.52226328495119 0.758083338329465 0.758083338329465 0.758083338329465
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Bag4 ENSMUSG00000037316 0.621603866745242 0.800562400888593 0.794449144111913 0.800562400888593 0.800562400888593 0.800562400888593
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Hspb8 ENSMUSG00000041548 0.812800065306927 0.812800065306927 0.3509099291417 0.812800065306927 0.755176388819689 0.812800065306927
Rps19bp1 ENSMUSG00000051518 0.316936700314695 0.316936700314695 0.110795756493675 0.316936700314695 0.26299484426459 0.316936700314695
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Ptges3 ENSMUSG00000071072 0.794466403205246 0.794466403205246 0.0539401077163417 0.161820323149025 0.596673651918825 0.794466403205246

Cellular responses to external stimuli

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Itfg2 ENSMUSG00000001518 0.285627844823271 0.511168106935029 0.340778737956686 0.511168106935029 0.722399668243088 0.722399668243088
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Atp6v1f ENSMUSG00000004285 0.0690338633958723 0.207101590187617 0.222939063628633 0.33440859544295 0.496913393196454 0.496913393196454
Prdx2 ENSMUSG00000005161 0.0985281296181431 0.147792194427215 0.0389210324359993 0.116763097307998 0.449744765248894 0.449744765248894
Txn2 ENSMUSG00000005354 0.0964782040204012 0.144717306030602 0.0434143896562025 0.130243168968607 0.243191665062254 0.243191665062254
Dnajb1 ENSMUSG00000005483 0.0586319192556633 0.17589575776699 0.365224250049953 0.547836375074929 0.918239798940416 0.918239798940416
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Atp6v0d1 ENSMUSG00000013160 0.309561343978414 0.46434201596762 0.104014014296183 0.312042042888548 0.840455578977424 0.840455578977424
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Dnajc7 ENSMUSG00000014195 0.86204782294864 0.86204782294864 0.545717554455601 0.86204782294864 0.655272326469404 0.86204782294864
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Arnt ENSMUSG00000015522 0.737068311927084 0.911987634815449 0.834214517176173 0.911987634815449 0.911987634815449 0.911987634815449
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Kdm6b ENSMUSG00000018476 0.484195545231719 0.626973949023456 0.413265451928212 0.626973949023456 0.626973949023456 0.626973949023456
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Cabin1 ENSMUSG00000020196 0.435937778483662 0.9685027681816 0.949631362231867 0.9685027681816 0.9685027681816 0.9685027681816
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Nprl3 ENSMUSG00000020289 0.203702664069119 0.611107992207356 0.722382308562153 0.722382308562153 0.675532889963341 0.722382308562153
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Mink1 ENSMUSG00000020827 0.649824575103585 0.868347543600674 0.868347543600674 0.868347543600674 0.690113908065094 0.868347543600674
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ero1l ENSMUSG00000021831 0.271532657293146 0.779263764807282 0.779263764807282 0.779263764807282 0.704676658498023 0.779263764807282
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
St13 ENSMUSG00000022403 0.0226590047737139 0.0679770143211418 0.604803815022533 0.896293316948781 0.896293316948781 0.896293316948781
Hsf1 ENSMUSG00000022556 0.990550908712948 0.990550908712948 0.330808024830752 0.990550908712948 0.855851704034247 0.990550908712948
Hira ENSMUSG00000022702 0.886996121840201 0.886996121840201 0.635615261017125 0.886996121840201 0.880766082782286 0.886996121840201
Ets2 ENSMUSG00000022895 0.902614134126358 0.965370466591231 0.128069196665605 0.384207589996814 0.965370466591231 0.965370466591231
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Hspa9 ENSMUSG00000024359 0.874372392628939 0.874372392628939 0.130956750318228 0.392870250954683 0.692572140526636 0.874372392628939
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Prdx3 ENSMUSG00000024997 0.672673674526661 0.672673674526661 0.514604671968294 0.672673674526661 0.479486628055555 0.672673674526661
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Wdr24 ENSMUSG00000025737 0.0413116303984237 0.123934891195271 0.32483174034334 0.32483174034334 0.21534725888783 0.323020888331744
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Dnajb6 ENSMUSG00000029131 0.219922417387641 0.659767252162924 0.572241105334608 0.785322790404261 0.785322790404261 0.785322790404261
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ep400 ENSMUSG00000029505 0.489403160139127 0.678508023538091 0.678508023538091 0.678508023538091 0.545682664333404 0.678508023538091
Pot1a ENSMUSG00000029676 0.632850922486848 0.632850922486848 0.504454253028015 0.632850922486848 0.569575432520929 0.632850922486848
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Bag3 ENSMUSG00000030847 0.367173382225697 0.758025819441381 0.658276336671019 0.758025819441381 0.758025819441381 0.758025819441381
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Terf2 ENSMUSG00000031921 0.773244268082692 0.952795428259095 0.899501396840473 0.952795428259095 0.952795428259095 0.952795428259095
Sesn3 ENSMUSG00000032009 0.862132884045171 0.871454989825358 0.43639747677031 0.871454989825358 0.871454989825358 0.871454989825358
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Flcn ENSMUSG00000032633 0.276517143972942 0.414775715959413 0.0997574634578557 0.299272390373567 0.834211485220143 0.834211485220143
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Szt2 ENSMUSG00000033253 0.247980080472639 0.743940241417916 0.968517890437885 0.968517890437885 0.501934467396805 0.752901701095207
Atp6v0b ENSMUSG00000033379 0.241222590971426 0.361833886457138 0.110098072216306 0.330294216648917 0.534927117587497 0.534927117587497
Ccar2 ENSMUSG00000033712 0.336634005703503 0.758083338329465 0.52226328495119 0.758083338329465 0.758083338329465 0.758083338329465
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Sh3bp4 ENSMUSG00000036206 0.728324311980814 0.728324311980814 0.380299381820909 0.728324311980814 0.532628101354366 0.728324311980814
Wtip ENSMUSG00000036459 0.0293607558774252 0.0880822676322757 0.883849026562423 0.883849026562423 0.504113347161587 0.75617002074238
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Bag4 ENSMUSG00000037316 0.621603866745242 0.800562400888593 0.794449144111913 0.800562400888593 0.800562400888593 0.800562400888593
Depdc5 ENSMUSG00000037426 0.887011276666238 0.887011276666238 0.450420881006587 0.887011276666238 0.828115067084511 0.887011276666238
Acd ENSMUSG00000038000 0.367503836873599 0.620144848380297 0.413429898920198 0.620144848380297 0.849744691475226 0.849744691475226
Sesn1 ENSMUSG00000038332 0.837319717555166 0.921391976146298 0.921391976146298 0.921391976146298 0.880747480616058 0.921391976146298
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Ubn1 ENSMUSG00000039473 0.577570541594651 0.96222021369151 0.707655755575611 0.96222021369151 0.96222021369151 0.96222021369151
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Cited2 ENSMUSG00000039910 0.296426512311656 0.296426512311656 0.236651113528526 0.296426512311656 0.261261147442375 0.296426512311656
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Hspb8 ENSMUSG00000041548 0.812800065306927 0.812800065306927 0.3509099291417 0.812800065306927 0.755176388819689 0.812800065306927
Mios ENSMUSG00000042447 0.794425526450263 0.987402692625264 0.566935300080862 0.987402692625264 0.987402692625264 0.987402692625264
B630005N14Rik ENSMUSG00000042742 0.707658154296541 0.740198014957057 0.740198014957057 0.740198014957057 0.704685054821577 0.740198014957057
Hmga1 ENSMUSG00000046711 0.737218293142865 0.7762549200246 0.457684286080448 0.7762549200246 0.7762549200246 0.7762549200246
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Rps19bp1 ENSMUSG00000051518 0.316936700314695 0.316936700314695 0.110795756493675 0.316936700314695 0.26299484426459 0.316936700314695
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
BC048403 ENSMUSG00000053684 0.666965593816086 0.930812612865626 0.402201800017423 0.930812612865626 0.930812612865626 0.930812612865626
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Egln2 ENSMUSG00000058709 0.419585870973821 0.629378806460731 0.302033889838096 0.629378806460731 0.940131257795237 0.940131257795237
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Ptges3 ENSMUSG00000071072 0.794466403205246 0.794466403205246 0.0539401077163417 0.161820323149025 0.596673651918825 0.794466403205246
Map3k5 ENSMUSG00000071369 0.946505334041831 0.946505334041831 0.464790285810797 0.946505334041831 0.883889101846502 0.946505334041831
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Global Genome Nucleotide Excision Repair (GG-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Pias3 ENSMUSG00000028101 0.618855247406317 0.72239720122654 0.72239720122654 0.72239720122654 0.236830193437193 0.710490580311578
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Rnf111 ENSMUSG00000032217 0.564236128590205 0.93393304076485 0.809701752702623 0.93393304076485 0.93393304076485 0.93393304076485
Pias1 ENSMUSG00000032405 0.661237056103372 0.746155333871313 0.746155333871313 0.746155333871313 0.593925445543173 0.746155333871313
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Usp45 ENSMUSG00000040455 0.427099674201283 0.981105959111385 0.868332276481305 0.981105959111385 0.981105959111385 0.981105959111385
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271

Regulation of HSF1-mediated heat shock response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dnajb1 ENSMUSG00000005483 0.0586319192556633 0.17589575776699 0.365224250049953 0.547836375074929 0.918239798940416 0.918239798940416
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Dnajc7 ENSMUSG00000014195 0.86204782294864 0.86204782294864 0.545717554455601 0.86204782294864 0.655272326469404 0.86204782294864
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
St13 ENSMUSG00000022403 0.0226590047737139 0.0679770143211418 0.604803815022533 0.896293316948781 0.896293316948781 0.896293316948781
Hsf1 ENSMUSG00000022556 0.990550908712948 0.990550908712948 0.330808024830752 0.990550908712948 0.855851704034247 0.990550908712948
Hspa9 ENSMUSG00000024359 0.874372392628939 0.874372392628939 0.130956750318228 0.392870250954683 0.692572140526636 0.874372392628939
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Dnajb6 ENSMUSG00000029131 0.219922417387641 0.659767252162924 0.572241105334608 0.785322790404261 0.785322790404261 0.785322790404261
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Bag3 ENSMUSG00000030847 0.367173382225697 0.758025819441381 0.658276336671019 0.758025819441381 0.758025819441381 0.758025819441381
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Ccar2 ENSMUSG00000033712 0.336634005703503 0.758083338329465 0.52226328495119 0.758083338329465 0.758083338329465 0.758083338329465
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Bag4 ENSMUSG00000037316 0.621603866745242 0.800562400888593 0.794449144111913 0.800562400888593 0.800562400888593 0.800562400888593
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Rps19bp1 ENSMUSG00000051518 0.316936700314695 0.316936700314695 0.110795756493675 0.316936700314695 0.26299484426459 0.316936700314695
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Transcriptional Regulation by E2F6

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Pcgf2 ENSMUSG00000018537 0.946504827049624 0.984256529444916 0.524881046437188 0.984256529444916 0.984256529444916 0.984256529444916
L3mbtl2 ENSMUSG00000022394 0.14597002513749 0.254066572653045 0.16937771510203 0.254066572653045 0.782266228811095 0.782266228811095
Epc1 ENSMUSG00000024240 0.16573552702746 0.497206581082381 0.393337278290945 0.590005917436418 0.632780075332655 0.632780075332655
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Pcgf6 ENSMUSG00000025050 0.758178056805396 0.946510665533973 0.716486625058548 0.946510665533973 0.946510665533973 0.946510665533973
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Mga ENSMUSG00000033943 0.247957790892636 0.603307914405705 0.40220527627047 0.603307914405705 0.632801060084072 0.632801060084072
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Max ENSMUSG00000059436 0.722392653421377 0.930812666801164 0.855938138929478 0.930812666801164 0.930812666801164 0.930812666801164
Rybp ENSMUSG00000072872 0.386764557826432 0.580146836739649 0.382296177582122 0.580146836739649 0.849676161042615 0.849676161042615

Regulation of Glucokinase by Glucokinase Regulatory Protein

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Signaling by WNT

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt3 ENSMUSG00000000125 0.714481500581681 0.92230967493487 0.86734876587097 0.92230967493487 0.92230967493487 0.92230967493487
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Nlk ENSMUSG00000017376 0.770180152451643 0.927660812353485 0.280306331636382 0.840918994909145 0.927660812353485 0.927660812353485
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Vps26a ENSMUSG00000020078 0.0226461030043265 0.0679383090129794 0.426884666182223 0.640326999273335 0.89631123412284 0.89631123412284
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Tert ENSMUSG00000021611 0.81582851704757 0.81582851704757 0.701754634531338 0.81582851704757 0.397594673419908 0.81582851704757
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Csnk1a1 ENSMUSG00000024576 0.346327182522591 0.91188749144334 0.806631502613227 0.91188749144334 0.91188749144334 0.91188749144334
Tle4 ENSMUSG00000024642 0.602224179001979 0.890139481950588 0.494410448307339 0.890139481950588 0.890139481950588 0.890139481950588
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Klhl12 ENSMUSG00000026455 0.352783397921336 0.529175096882004 0.125101084204549 0.375303252613647 0.684216646430846 0.684216646430846
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Gnb4 ENSMUSG00000027669 0.896378254629603 0.896378254629603 0.719429887176208 0.896378254629603 0.58855098108693 0.896378254629603
Wnt2b ENSMUSG00000027840 0.873375253288832 0.873375253288832 0.462139546938377 0.873375253288832 0.823522346561903 0.873375253288832
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Gnb1 ENSMUSG00000029064 0.752112227583879 0.752112227583879 0.424800141460724 0.752112227583879 0.635590066427997 0.752112227583879
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Gnb2 ENSMUSG00000029713 0.014591268837441 0.0218869032561615 0.0119929612037782 0.0218869032561615 0.924500360031433 0.924500360031433
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ctbp2 ENSMUSG00000030970 0.883902463930184 0.918273634779434 0.852839917479334 0.918273634779434 0.918273634779434 0.918273634779434
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Vps35 ENSMUSG00000031696 0.113719590095891 0.341158770287674 0.319104328947984 0.47462991900775 0.47462991900775 0.47462991900775
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Wnt6 ENSMUSG00000033227 0.645708110911216 0.858593327573213 0.277065349389378 0.831196048168134 0.858593327573213 0.858593327573213
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Bcl9 ENSMUSG00000038256 0.896373353412303 0.896373353412303 0.457666626209848 0.896373353412303 0.687144969868415 0.896373353412303
Gng10 ENSMUSG00000038607 0.779298584363925 0.89325835750727 0.89325835750727 0.89325835750727 0.369641003660815 0.89325835750727
Smurf1 ENSMUSG00000038780 0.707654322545349 0.83122888698568 0.574985281823994 0.83122888698568 0.83122888698568 0.83122888698568
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Znrf3 ENSMUSG00000041961 0.669838157542233 0.890125877803797 0.599491046815055 0.890125877803797 0.890125877803797 0.890125877803797
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Gng2 ENSMUSG00000043004 0.803607853159088 0.803607853159088 0.746086303777471 0.803607853159088 0.30193486428631 0.803607853159088
Dact1 ENSMUSG00000044548 0.949652415064117 0.949652415064117 0.344812058845794 0.74162515864759 0.494416772431727 0.74162515864759
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Pygo2 ENSMUSG00000047824 0.627240891024233 0.868349262275774 0.101434829373398 0.304304488120195 0.868349262275774 0.868349262275774
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Amer1 ENSMUSG00000050332 0.317133822680462 0.630021125667124 0.630021125667124 0.630021125667124 0.452818916389513 0.630021125667124
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Chd8 ENSMUSG00000053754 0.767161056208826 0.987403630907266 0.987403630907266 0.987403630907266 0.638435264150091 0.987403630907266
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Bcl9l ENSMUSG00000063382 0.719441532431034 0.719441532431034 0.315129286028421 0.719441532431034 0.666880765429892 0.719441532431034
Gng8 ENSMUSG00000063594 0.644090126802365 0.649764722457812 0.649764722457812 0.649764722457812 0.455188806742285 0.649764722457812
Frat1 ENSMUSG00000067199 0.170247366619243 0.255371049928864 0.125509925421442 0.255371049928864 0.285775076922933 0.285775076922933
Sox4 ENSMUSG00000076431 0.946492708629395 0.946492708629395 0.649725485744156 0.946492708629395 0.31503730288715 0.94511190866145
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Formation of the Early Elongation Complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Nelfcd ENSMUSG00000016253 0.0834779780780214 0.125216967117032 0.0206069569828155 0.0618208709484465 0.410780464027787 0.410780464027787
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Nelfe ENSMUSG00000024369 0.940159202524197 0.940159202524197 0.24773973841765 0.743219215252951 0.710373703465163 0.940159202524197
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Nelfa ENSMUSG00000029111 0.924532065689256 0.924532065689256 0.472197769958753 0.798863237768038 0.532575491845359 0.798863237768038
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Ctdp1 ENSMUSG00000033323 0.689973604646127 0.868326273067579 0.467145937445248 0.868326273067579 0.868326273067579 0.868326273067579
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Centrosome maturation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

Recruitment of mitotic centrosome proteins and complexes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

Processing of Intronless Pre-mRNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029

Intra-Golgi traffic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847

Neddylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo9 ENSMUSG00000001366 0.213593913192257 0.460696954000312 0.307131302666875 0.460696954000312 0.940194121838634 0.940194121838634
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Fbxo11 ENSMUSG00000005371 0.229006001463732 0.687018004391197 0.610471723108175 0.915707584662263 0.933935404170617 0.933935404170617
Ube2m ENSMUSG00000005575 0.514423072010292 0.771634608015438 0.244611969865383 0.73383590959615 0.785328358197432 0.785328358197432
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Fbxw5 ENSMUSG00000015095 0.312266225489717 0.583363918635638 0.388909279090426 0.583363918635638 0.818437948865218 0.818437948865218
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Wsb1 ENSMUSG00000017677 0.692964035503656 0.767165274931203 0.621531949939947 0.767165274931203 0.767165274931203 0.767165274931203
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Cand1 ENSMUSG00000020114 0.532628880282576 0.588494256711568 0.266363632771176 0.588494256711568 0.588494256711568 0.588494256711568
Fbxl20 ENSMUSG00000020883 0.443360548542608 0.72231253977434 0.599400170065276 0.72231253977434 0.72231253977434 0.72231253977434
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Fbxl3 ENSMUSG00000022124 0.940229459644943 0.940229459644943 0.837380940615728 0.940229459644943 0.672709743569768 0.940229459644943
Dcaf11 ENSMUSG00000022214 0.222574410264143 0.333861615396215 0.128980740980393 0.333861615396215 0.499343826799581 0.499343826799581
Spsb3 ENSMUSG00000024160 0.0132113072544738 0.0198169608817108 0.00050144460873919 0.00150433382621757 0.460065964929223 0.460065964929223
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Fbxl15 ENSMUSG00000025226 0.307695222968975 0.461542834453462 0.00805888483641587 0.0241766545092476 0.859033170480059 0.859033170480059
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Asb1 ENSMUSG00000026311 0.601944165244773 0.601944165244773 0.0636532260572407 0.190959678171722 0.454867103954538 0.601944165244773
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Klhl20 ENSMUSG00000026705 0.519684141499169 0.695920118882848 0.496896837138848 0.695920118882848 0.695920118882848 0.695920118882848
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Dcun1d1 ENSMUSG00000027708 8.10795627050442e-05 0.000243238688115133 0.0182788203713412 0.0274182305570119 0.695670533376091 0.695670533376091
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Nub1 ENSMUSG00000028954 0.315243633036749 0.764183193354547 0.537847393351677 0.764183193354547 0.764183193354547 0.764183193354547
Commd8 ENSMUSG00000029213 0.821925131826797 0.862093652847388 0.690103864566942 0.862093652847388 0.862093652847388 0.862093652847388
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Fbxl14 ENSMUSG00000030019 0.585733426897513 0.878600140346269 0.296343958092929 0.878600140346269 0.912009716457441 0.912009716457441
Kbtbd8 ENSMUSG00000030031 0.566939894440354 0.737225190462243 0.737225190462243 0.737225190462243 0.707644415368941 0.737225190462243
Asb7 ENSMUSG00000030509 0.886996648412827 0.886996648412827 0.722376332987625 0.886996648412827 0.855908935982981 0.886996648412827
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Fbxl19 ENSMUSG00000030811 0.859032111304213 0.859032111304213 0.624401770964706 0.859032111304213 0.821993934939889 0.859032111304213
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Ccdc22 ENSMUSG00000031143 0.607550712820628 0.607550712820628 0.215418375774768 0.607550712820628 0.599239281039663 0.607550712820628
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Nae1 ENSMUSG00000031878 0.825080834674905 0.834312035461909 0.386783536357782 0.834312035461909 0.834312035461909 0.834312035461909
Commd4 ENSMUSG00000032299 0.0734255678782446 0.220276703634734 0.411089384112583 0.596699420845023 0.596699420845023 0.596699420845023
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Fem1c ENSMUSG00000033319 0.908878957745757 0.908878957745757 0.266370389855722 0.799111169567166 0.728297759692514 0.908878957745757
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Asb6 ENSMUSG00000039483 0.918255734950225 0.918255734950225 0.862104557997622 0.918255734950225 0.692981424119149 0.918255734950225
Fbxl5 ENSMUSG00000039753 0.460089905660059 0.527349966742554 0.382374381325839 0.527349966742554 0.527349966742554 0.527349966742554
Spsb1 ENSMUSG00000039911 0.319080089631295 0.580187025826347 0.865240833296443 0.865240833296443 0.386791350550898 0.580187025826347
Klhl42 ENSMUSG00000040102 0.472026108099081 0.868301215980349 0.868301215980349 0.868301215980349 0.776168664106968 0.868301215980349
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Fbxw4 ENSMUSG00000040913 0.0822124854277177 0.224008023834634 0.149338682556422 0.224008023834634 0.707633447761154 0.707633447761154
Ccdc8 ENSMUSG00000041117 0.722333779317285 0.722333779317285 0.522286127004673 0.722333779317285 0.537725250716463 0.722333779317285
Commd10 ENSMUSG00000042705 0.333975226661427 0.797307701580356 0.797307701580356 0.797307701580356 0.577357289469794 0.797307701580356
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Dcun1d3 ENSMUSG00000048787 0.0446830301930137 0.134049090579041 0.522239834738647 0.783359752107971 0.94336638862497 0.94336638862497
Dcaf7 ENSMUSG00000049354 0.779251754242924 0.890124914594691 0.298363761411075 0.890124914594691 0.890124914594691 0.890124914594691
Gan ENSMUSG00000052557 0.313344114171842 0.470016171257763 0.26299500485965 0.470016171257763 0.681391720765928 0.681391720765928
Ubxn7 ENSMUSG00000053774 0.378158472049596 0.708274209461876 0.472182806307917 0.708274209461876 0.943363017302423 0.943363017302423
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Klhl5 ENSMUSG00000054920 0.441023563137958 0.556142046462253 0.540328093857368 0.556142046462253 0.556142046462253 0.556142046462253
Fbxo6 ENSMUSG00000055401 0.165725488149896 0.344494721839957 0.307467389409342 0.344494721839957 0.344494721839957 0.344494721839957
Klhl25 ENSMUSG00000055652 0.0531566348600952 0.159469904580285 0.219797201332521 0.329695801998782 0.342050703942181 0.342050703942181
Socs6 ENSMUSG00000056153 0.420212053945563 0.803600482650626 0.585800975843989 0.803600482650626 0.803600482650626 0.803600482650626
Commd7 ENSMUSG00000056941 0.652676785235519 0.987405591197671 0.987405591197671 0.987405591197671 0.740221145448748 0.987405591197671
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Fbxl12 ENSMUSG00000066892 0.514569590928347 0.771854386392521 0.968518283937401 0.968518283937401 0.404276434285822 0.771854386392521
Klhl9 ENSMUSG00000070923 0.143736999914835 0.431210999744505 0.417886281815373 0.62682942272306 0.95279382267016 0.95279382267016
Dda1 ENSMUSG00000074247 0.758049932577639 0.959057354226814 0.616040528394896 0.959057354226814 0.959057354226814 0.959057354226814
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Fbxw10 ENSMUSG00000090173 0.74415417304833 0.74415417304833 0.635518344743522 0.74415417304833 0.729025476397157 0.74415417304833
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Mitotic Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

RNA Polymerase III Transcription Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf3a ENSMUSG00000016503 0.101848345269951 0.152772517904927 0.0141417890799713 0.0424253672399139 0.977930494027345 0.977930494027345
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Gtf3c5 ENSMUSG00000026816 0.240001081265092 0.360001621897639 0.209608182047211 0.360001621897639 0.8036268665289 0.8036268665289
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Gtf3c1 ENSMUSG00000032777 0.514477384975409 0.771716077463113 0.326830323471223 0.771716077463113 0.990549428512413 0.990549428512413
Gtf3c4 ENSMUSG00000035666 0.984256165622295 0.984256165622295 0.162099658146484 0.486298974439453 0.921405886685337 0.984256165622295
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Gtf3c3 ENSMUSG00000041303 0.482006439491822 0.704726334199839 0.212555196216459 0.637665588649376 0.704726334199839 0.704726334199839
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806

TCF dependent signaling in response to WNT

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt3 ENSMUSG00000000125 0.714481500581681 0.92230967493487 0.86734876587097 0.92230967493487 0.92230967493487 0.92230967493487
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Tert ENSMUSG00000021611 0.81582851704757 0.81582851704757 0.701754634531338 0.81582851704757 0.397594673419908 0.81582851704757
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Csnk1a1 ENSMUSG00000024576 0.346327182522591 0.91188749144334 0.806631502613227 0.91188749144334 0.91188749144334 0.91188749144334
Tle4 ENSMUSG00000024642 0.602224179001979 0.890139481950588 0.494410448307339 0.890139481950588 0.890139481950588 0.890139481950588
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Klhl12 ENSMUSG00000026455 0.352783397921336 0.529175096882004 0.125101084204549 0.375303252613647 0.684216646430846 0.684216646430846
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Ctbp1 ENSMUSG00000037373 0.190021470094259 0.285032205141389 0.0112425133107826 0.0337275399323479 0.899484337853423 0.899484337853423
Bcl9 ENSMUSG00000038256 0.896373353412303 0.896373353412303 0.457666626209848 0.896373353412303 0.687144969868415 0.896373353412303
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Znrf3 ENSMUSG00000041961 0.669838157542233 0.890125877803797 0.599491046815055 0.890125877803797 0.890125877803797 0.890125877803797
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Dact1 ENSMUSG00000044548 0.949652415064117 0.949652415064117 0.344812058845794 0.74162515864759 0.494416772431727 0.74162515864759
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Pygo2 ENSMUSG00000047824 0.627240891024233 0.868349262275774 0.101434829373398 0.304304488120195 0.868349262275774 0.868349262275774
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Amer1 ENSMUSG00000050332 0.317133822680462 0.630021125667124 0.630021125667124 0.630021125667124 0.452818916389513 0.630021125667124
Chd8 ENSMUSG00000053754 0.767161056208826 0.987403630907266 0.987403630907266 0.987403630907266 0.638435264150091 0.987403630907266
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Bcl9l ENSMUSG00000063382 0.719441532431034 0.719441532431034 0.315129286028421 0.719441532431034 0.666880765429892 0.719441532431034
Frat1 ENSMUSG00000067199 0.170247366619243 0.255371049928864 0.125509925421442 0.255371049928864 0.285775076922933 0.285775076922933
Sox4 ENSMUSG00000076431 0.946492708629395 0.946492708629395 0.649725485744156 0.946492708629395 0.31503730288715 0.94511190866145
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

RNA Polymerase III Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf3a ENSMUSG00000016503 0.101848345269951 0.152772517904927 0.0141417890799713 0.0424253672399139 0.977930494027345 0.977930494027345
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Gtf3c5 ENSMUSG00000026816 0.240001081265092 0.360001621897639 0.209608182047211 0.360001621897639 0.8036268665289 0.8036268665289
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Gtf3c1 ENSMUSG00000032777 0.514477384975409 0.771716077463113 0.326830323471223 0.771716077463113 0.990549428512413 0.990549428512413
Gtf3c4 ENSMUSG00000035666 0.984256165622295 0.984256165622295 0.162099658146484 0.486298974439453 0.921405886685337 0.984256165622295
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Gtf3c3 ENSMUSG00000041303 0.482006439491822 0.704726334199839 0.212555196216459 0.637665588649376 0.704726334199839 0.704726334199839
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806

Nuclear Pore Complex (NPC) Disassembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

Mitotic Metaphase and Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Regulation of TP53 Activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ttc5 ENSMUSG00000006288 0.289245761101568 0.797531873832735 0.797531873832735 0.797531873832735 0.591266864698899 0.797531873832735
Hipk1 ENSMUSG00000008730 0.0940924963949365 0.28227748918481 0.713539120862588 0.713539120862588 0.684230035763789 0.713539120862588
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rffl ENSMUSG00000020696 0.499406497178666 0.569551782735742 0.309533365572562 0.569551782735742 0.569551782735742 0.569551782735742
Ppp1r13b ENSMUSG00000021285 0.707638838245221 0.785353922376112 0.785353922376112 0.785353922376112 0.779270489867307 0.785353922376112
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Taf11 ENSMUSG00000024218 0.946511082921324 0.962228294253525 0.962228294253525 0.962228294253525 0.849747244416998 0.962228294253525
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Banp ENSMUSG00000025316 0.352973634799885 0.352973634799885 0.0550155669365745 0.165046700809724 0.313355013846564 0.352973634799885
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Taf3 ENSMUSG00000025782 0.59667016370835 0.890113024801425 0.890113024801425 0.890113024801425 0.420103317460284 0.890113024801425
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Ssrp1 ENSMUSG00000027067 0.893074110220089 0.89307687270616 0.591251234724507 0.89307687270616 0.89307687270616 0.89307687270616
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Prkag2 ENSMUSG00000028944 0.918274871325169 0.927673387028193 0.877669144714702 0.927673387028193 0.927673387028193 0.927673387028193
Rnf34 ENSMUSG00000029474 0.627245123591803 0.713530587213568 0.40665618042614 0.713530587213568 0.713530587213568 0.713530587213568
Taf1 ENSMUSG00000031314 0.767183814382693 0.767183814382693 0.698832448320939 0.767183814382693 0.455259687777215 0.767183814382693
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Taf6 ENSMUSG00000036980 0.754844289133487 0.754844289133487 0.309293412269241 0.754844289133487 0.524197729068695 0.754844289133487
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Taf4a ENSMUSG00000039117 0.946505769447161 0.946505769447161 0.843564864901824 0.946505769447161 0.883897225204395 0.946505769447161
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Taf13 ENSMUSG00000048100 0.788373285372395 0.962217084611529 0.962217084611529 0.962217084611529 0.621591669104263 0.962217084611529
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Prkaa1 ENSMUSG00000050697 0.350895362275322 0.908882270006441 0.908882270006441 0.908882270006441 0.658367741350229 0.908882270006441
Taf7 ENSMUSG00000051316 0.292866956880604 0.672207513233765 0.448138342155843 0.672207513233765 0.800571187502943 0.800571187502943
Taf9 ENSMUSG00000052293 0.110987267142872 0.166480900714309 0.0857586640378365 0.166480900714309 0.591152148076007 0.591152148076007
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Prkag1 ENSMUSG00000067713 0.0630601745572846 0.0945902618359269 0.00823942330208104 0.0247182699062431 0.274800297867361 0.274800297867361

Mitotic Prometaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Numa1 ENSMUSG00000066306 0.862112472143811 0.862112472143811 0.524888831496724 0.862112472143811 0.621580834430389 0.862112472143811
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753

RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Smarcb1 ENSMUSG00000000902 0.21103781374597 0.316556720618955 0.158559221295776 0.316556720618955 0.849722190121545 0.849722190121545
Arid1a ENSMUSG00000007880 0.899500180223969 0.921403726224452 0.649812526697506 0.921403726224452 0.921403726224452 0.921403726224452
Smarcd1 ENSMUSG00000023018 0.669839337528698 0.946508858730321 0.908881540732346 0.946508858730321 0.946508858730321 0.946508858730321
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Smarcc2 ENSMUSG00000025369 0.977961375221315 0.993702501737413 0.943370043367547 0.993702501737413 0.993702501737413 0.993702501737413
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Smarcc1 ENSMUSG00000032481 0.877670879374508 0.877670879374508 0.227411333488226 0.682234000464678 0.661204085023021 0.877670879374508
Arid2 ENSMUSG00000033237 0.504463594873527 0.886882946790675 0.968520149345926 0.968520149345926 0.59125529786045 0.886882946790675
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Pbrm1 ENSMUSG00000042323 0.332781366012591 0.927675126505199 0.927675126505199 0.927675126505199 0.687195090298477 0.927675126505199
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Arid1b ENSMUSG00000069729 0.896364343022659 0.905737704015925 0.893256130336894 0.905737704015925 0.905737704015925 0.905737704015925
Rybp ENSMUSG00000072872 0.386764557826432 0.580146836739649 0.382296177582122 0.580146836739649 0.849676161042615 0.849676161042615

mRNA Splicing - Minor Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prpf6 ENSMUSG00000002455 0.713514986100439 0.713514986100439 0.537747903931352 0.713514986100439 0.509408277258403 0.713514986100439
Snrpd1 ENSMUSG00000002477 0.831219920926164 0.831219920926164 0.773219042286712 0.831219920926164 0.81279505897939 0.831219920926164
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Ddx23 ENSMUSG00000003360 0.553585725602489 0.591248747030693 0.332794851311256 0.591248747030693 0.591248747030693 0.591248747030693
Snrnp200 ENSMUSG00000003660 0.996850860426634 0.996850860426634 0.294635386022539 0.441953079033808 0.233529322833175 0.441953079033808
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Srsf1 ENSMUSG00000018379 0.915137811015715 0.915137811015715 0.868345606369238 0.915137811015715 0.737240453091827 0.915137811015715
Ddx42 ENSMUSG00000020705 0.618819029290968 0.797470493750577 0.558924598023973 0.797470493750577 0.797470493750577 0.797470493750577
Prpf8 ENSMUSG00000020850 0.818877529916093 0.818877529916093 0.3210451664377 0.481567749656551 0.307490827838566 0.481567749656551
Eftud2 ENSMUSG00000020929 0.408653324911151 0.42216218547522 0.100581074306473 0.301743222919418 0.42216218547522 0.42216218547522
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Sf3b2 ENSMUSG00000024853 0.690022495977405 0.981103992590159 0.311444649596969 0.934333948790906 0.981103992590159 0.981103992590159
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Rnpc3 ENSMUSG00000027981 0.496926771619955 0.745390157429933 0.251292362417855 0.745390157429933 0.927676463240204 0.927676463240204
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Sf3b3 ENSMUSG00000033732 0.591154969450222 0.591154969450222 0.162111505753855 0.243167258630783 0.135189999835798 0.243167258630783
0610009D07Rik ENSMUSG00000037361 0.514527728351381 0.918269624711916 0.672716391100531 0.918269624711916 0.918269624711916 0.918269624711916
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Snrnp25 ENSMUSG00000040767 0.144873289929696 0.381892931885658 0.254595287923772 0.381892931885658 0.530061457689675 0.530061457689675
Txnl4a ENSMUSG00000057130 0.236357181189437 0.354535771784155 0.230151656915334 0.354535771784155 0.489307092916846 0.489307092916846
Nhp2l1 ENSMUSG00000063480 0.837385399296325 0.868348650551674 0.868348650551674 0.868348650551674 0.669853982191742 0.868348650551674
Sf3b4 ENSMUSG00000068856 0.984250687659528 0.984250687659528 0.871453680868353 0.984250687659528 0.837326153079468 0.984250687659528
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Protein ubiquitination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Hltf ENSMUSG00000002428 0.469559400197792 0.783035674339656 0.522023782893104 0.783035674339656 0.984253887202867 0.984253887202867
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Rnf144a ENSMUSG00000020642 0.785340357892338 0.785340357892338 0.448119551026687 0.704626611701217 0.469751074467478 0.704626611701217
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Wac ENSMUSG00000024283 0.0434174539866481 0.130252361959944 0.429356293987237 0.452649977383344 0.452649977383344 0.452649977383344
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Rnf20 ENSMUSG00000028309 0.76415898641512 0.924530595215217 0.924530595215217 0.924530595215217 0.865241638042382 0.924530595215217
Pex14 ENSMUSG00000028975 0.194171505737175 0.291257258605763 0.080828462166762 0.242485386500286 0.971666162661201 0.971666162661201
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Rad18 ENSMUSG00000030254 0.274811771450367 0.577392108098863 0.450487835959263 0.577392108098863 0.577392108098863 0.577392108098863
Rnf40 ENSMUSG00000030816 0.322848210432661 0.603267145078526 0.402178096719017 0.603267145078526 0.930785590716957 0.930785590716957
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Shprh ENSMUSG00000090112 0.561578278019075 0.561578278019075 0.378124993618767 0.561578278019075 0.330806941366433 0.561578278019075
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

mRNA Capping

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.855891963062675 0.930789246918887 0.803626350984924 0.930789246918887 0.930789246918887 0.930789246918887
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Khsrp ENSMUSG00000007670 0.837321743303952 0.921404784610143 0.921404784610143 0.921404784610143 0.862068813004363 0.921404784610143
Tnpo1 ENSMUSG00000009470 0.494417786200833 0.788383945704149 0.788383945704149 0.788383945704149 0.687209982750423 0.788383945704149
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Anp32a ENSMUSG00000032249 0.740192056526801 0.818916972373276 0.818916972373276 0.818916972373276 0.73124464254036 0.818916972373276
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Mitotic G2-G2/M phases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Fkbpl ENSMUSG00000033739 0.522200976154869 0.862104054739938 0.862104054739938 0.862104054739938 0.687192773503887 0.862104054739938
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Synthesis of PIPs at the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Inpp5k ENSMUSG00000006127 0.566857130340692 0.854429356932178 0.89010984134026 0.89010984134026 0.569619571288119 0.854429356932178
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Mtmr1 ENSMUSG00000015214 0.28209068750968 0.613378299339732 0.408918866226488 0.613378299339732 0.990553880737655 0.990553880737655
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Rufy1 ENSMUSG00000020375 0.740130266115853 0.949614807003285 0.669755040840901 0.949614807003285 0.949614807003285 0.949614807003285
Mtmr6 ENSMUSG00000021987 0.113641206247705 0.340923618743115 0.384520718380111 0.576781077570167 0.987405339532972 0.987405339532972
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Pik3c2b ENSMUSG00000026447 0.89013405796377 0.959082860407753 0.664102524050534 0.959082860407753 0.959082860407753 0.959082860407753
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Mtmr9 ENSMUSG00000035078 0.927673926601617 0.927673926601617 0.460088851731596 0.795020709426467 0.530013806284311 0.795020709426467
Plekha1 ENSMUSG00000040268 0.0565578015598726 0.169673404679618 0.41776716443371 0.516947777848175 0.516947777848175 0.516947777848175
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Plekha6 ENSMUSG00000041757 0.322936013292587 0.955938218410897 0.761148030256025 0.955938218410897 0.955938218410897 0.955938218410897
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847

ER to Golgi Anterograde Transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902

G2/M Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Fkbpl ENSMUSG00000033739 0.522200976154869 0.862104054739938 0.862104054739938 0.862104054739938 0.687192773503887 0.862104054739938
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Fbxl7 ENSMUSG00000043556 0.457543009907093 0.506447494899284 0.506447494899284 0.506447494899284 0.142093074422676 0.426279223268028
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Fbxl18 ENSMUSG00000066640 0.79753094491796 0.79753094491796 0.72239301012005 0.79753094491796 0.613301448577685 0.79753094491796
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Recruitment of NuMA to mitotic centrosomes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubgcp3 ENSMUSG00000000759 0.664102524050534 0.664102524050534 0.548346447032895 0.664102524050534 0.469744367339769 0.664102524050534
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Tubgcp2 ENSMUSG00000025474 0.228866085928145 0.343299128892217 0.134202387618026 0.343299128892217 0.564169740200238 0.564169740200238
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tubgcp4 ENSMUSG00000027263 0.350919316180708 0.596686660096922 0.596686660096922 0.596686660096922 0.558893746953191 0.596686660096922
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mzt1 ENSMUSG00000033186 0.55624741266673 0.921400157137687 0.921400157137687 0.921400157137687 0.896370660898406 0.921400157137687
Tubgcp5 ENSMUSG00000033790 0.840461327390056 0.840461327390056 0.479511400686158 0.719267101029237 0.424811076384558 0.719267101029237
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Tubgcp6 ENSMUSG00000051786 0.865219397905048 0.865219397905048 0.758150448615193 0.865219397905048 0.75817769050266 0.865219397905048
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Numa1 ENSMUSG00000066306 0.862112472143811 0.862112472143811 0.524888831496724 0.862112472143811 0.621580834430389 0.862112472143811

Anchoring of the basal body to the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ccdc41 ENSMUSG00000020024 0.0767204865353 0.2301614596059 0.359058162416547 0.538587243624821 0.737191999201571 0.737191999201571
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Cep97 ENSMUSG00000022604 0.373879244215948 0.949641223502237 0.949641223502237 0.949641223502237 0.74314391198049 0.949641223502237
Cep89 ENSMUSG00000023072 0.233559506921179 0.658347900312982 0.658347900312982 0.658347900312982 0.574934719901611 0.658347900312982
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Tmem216 ENSMUSG00000024667 0.417854541537638 0.474624532646932 0.474624532646932 0.474624532646932 0.459977954546563 0.474624532646932
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Kif24 ENSMUSG00000028438 0.540447942857581 0.868345300482773 0.6756105600846 0.868345300482773 0.868345300482773 0.868345300482773
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mks1 ENSMUSG00000034121 0.133166636948269 0.399499910844806 0.719435229766814 0.719435229766814 0.602181528550136 0.719435229766814
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
C2cd3 ENSMUSG00000047248 0.489429390732886 0.604982556408182 0.138390379060489 0.415171137181468 0.604982556408182 0.604982556408182
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
4922501C03Rik ENSMUSG00000056919 0.675543696009354 0.908841494951936 0.908841494951936 0.908841494951936 0.785248613234626 0.908841494951936
Sclt1 ENSMUSG00000059834 0.749181725715864 0.837391361537029 0.837391361537029 0.837391361537029 0.613301726166376 0.837391361537029
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

Postmitotic nuclear pore complex (NPC) reformation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091

Dual incision in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Ub-specific processing proteases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.743049721377174 0.859013369289371 0.859013369289371 0.859013369289371 0.661055329572313 0.859013369289371
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Keap1 ENSMUSG00000003308 0.145834753249507 0.218752129874261 0.081511350013963 0.218752129874261 0.933924254917951 0.933924254917951
Ufd1l ENSMUSG00000005262 0.591252229789365 0.591252229789365 0.328797396458557 0.591252229789365 0.434033727036496 0.591252229789365
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Usp19 ENSMUSG00000006676 0.555985360729751 0.743015676480996 0.092602981624798 0.277808944874394 0.743015676480996 0.743015676480996
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Fkbp8 ENSMUSG00000019428 0.0754988039267296 0.226496411780189 0.397661585885481 0.501093706078811 0.501093706078811 0.501093706078811
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Hif1a ENSMUSG00000021109 0.971665248773398 0.971665248773398 0.740221341206485 0.971665248773398 0.580377339873273 0.971665248773398
Atxn7 ENSMUSG00000021738 0.300230842914402 0.900692528743205 0.773245376445156 0.921407802086672 0.921407802086672 0.921407802086672
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Smad2 ENSMUSG00000024563 0.635660084673789 0.908882472579471 0.908882472579471 0.908882472579471 0.704721116284447 0.908882472579471
Otub1 ENSMUSG00000024767 0.2998765079153 0.2998765079153 0.185928139933512 0.2998765079153 0.250990052949487 0.2998765079153
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Rce1 ENSMUSG00000024889 0.556266879142241 0.834400318713362 0.110081838544872 0.330245515634615 0.990553944009068 0.990553944009068
Usp33 ENSMUSG00000025437 0.491903194177525 0.737854791266288 0.908875584338405 0.908875584338405 0.484443431720096 0.737854791266288
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Usp16 ENSMUSG00000025616 0.641287562523823 0.641287562523823 0.261021554656134 0.641287562523823 0.632763573931717 0.641287562523823
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Usp24 ENSMUSG00000028514 0.80665519534199 0.874551056307771 0.326891407506396 0.874551056307771 0.874551056307771 0.874551056307771
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Tada2b ENSMUSG00000029196 0.406557368296659 0.693030382940719 0.693030382940719 0.693030382940719 0.610435525360737 0.693030382940719
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Usp12 ENSMUSG00000029640 0.779285739065985 0.915135318836707 0.862138477061457 0.915135318836707 0.915135318836707 0.915135318836707
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Smad1 ENSMUSG00000031681 0.658360663322051 0.959074710741414 0.375981372273027 0.959074710741414 0.959074710741414 0.959074710741414
Usp10 ENSMUSG00000031826 0.431196316155006 0.704660933121012 0.704660933121012 0.704660933121012 0.658011866762809 0.704660933121012
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Usp4 ENSMUSG00000032612 0.476276255657081 0.669269987649272 0.213927345158588 0.641782035475763 0.669269987649272 0.669269987649272
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Usp37 ENSMUSG00000033364 0.157368156181812 0.472104468545437 0.940226488909329 0.940226488909329 0.834308461857482 0.940226488909329
Becn1 ENSMUSG00000035086 0.601903011199835 0.601903011199835 0.152659973305434 0.457979919916301 0.511605163190498 0.601903011199835
Siah2 ENSMUSG00000036432 0.613300060625295 0.809665982159559 0.0117415296862778 0.0352245890588333 0.809665982159559 0.809665982159559
Cyld ENSMUSG00000036712 0.893249471687713 0.98110763185907 0.773243036549786 0.98110763185907 0.98110763185907 0.98110763185907
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Adrm1 ENSMUSG00000039041 0.104965021816539 0.157447532724809 0.0397463098480413 0.119238929544124 0.571749204282725 0.571749204282725
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Mat2b ENSMUSG00000042032 0.42020009065683 0.630300135985245 0.908878380342246 0.908878380342246 0.411153687199577 0.630300135985245
Usp48 ENSMUSG00000043411 0.675576381154849 0.779281728953017 0.459996534139036 0.779281728953017 0.779281728953017 0.779281728953017
Taf9b ENSMUSG00000047242 0.530059710112281 0.795089565168422 0.467334460532197 0.795089565168422 0.930808474863292 0.930808474863292
Tada3 ENSMUSG00000048930 0.445386787053696 0.668080180580543 0.127981844316683 0.383945532950048 0.893137831012048 0.893137831012048
Usp42 ENSMUSG00000051306 0.517173520468805 0.852835531331225 0.669841315712961 0.852835531331225 0.852835531331225 0.852835531331225
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Usp34 ENSMUSG00000056342 0.158553228771063 0.384324858217952 0.256216572145302 0.384324858217952 0.940225069993647 0.940225069993647
Birc2 ENSMUSG00000057367 0.981109306271104 0.981109306271104 0.618827653585515 0.961907359960164 0.641271573306776 0.961907359960164
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Suds3 ENSMUSG00000066900 0.101609371598545 0.152414057397818 0.000280597779316969 0.000841793337950907 0.428705638920795 0.428705638920795
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Xrcc1 ENSMUSG00000051768 0.373889676064885 0.560834514097327 0.311472140296653 0.560834514097327 0.782330754853731 0.782330754853731
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Formation of TC-NER Pre-Incision Complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Fanconi Anemia Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Ercc1 ENSMUSG00000003549 0.332660071786614 0.537707689925562 0.537707689925562 0.537707689925562 0.363257675555568 0.537707689925562
Fance ENSMUSG00000007570 0.095706501306675 0.287119503920025 0.393223216571204 0.589834824856806 0.855882327545643 0.855882327545643
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Fancc ENSMUSG00000021461 0.10483914522132 0.314517435663961 0.4869456968576 0.566921429433929 0.566921429433929 0.566921429433929
Ercc4 ENSMUSG00000022545 0.599462407090388 0.855932029264145 0.855932029264145 0.855932029264145 0.767204369306622 0.855932029264145
Mus81 ENSMUSG00000024906 0.317161644537185 0.317161644537185 0.309558578812616 0.317161644537185 0.309567687476581 0.317161644537185
2310003H01Rik ENSMUSG00000025384 0.324918975433978 0.487378463150967 0.166897119453255 0.487378463150967 0.591192347167402 0.591192347167402
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Fancg ENSMUSG00000028453 0.632842106829348 0.800580125546944 0.303934036067089 0.800580125546944 0.800580125546944 0.800580125546944
Wdr48 ENSMUSG00000032512 0.314877511389705 0.472316267084557 0.281623069208712 0.472316267084557 0.949625195292448 0.949625195292448
Fan1 ENSMUSG00000033458 0.0895463814162714 0.268639144248814 0.535210742769633 0.535210742769633 0.417936826467238 0.535210742769633
Fancd2 ENSMUSG00000034023 0.971642734179405 0.971642734179405 0.933888899380019 0.971642734179405 0.818914011107705 0.971642734179405
Slx4 ENSMUSG00000039738 0.472155600959342 0.865220680142318 0.728303881107593 0.865220680142318 0.865220680142318 0.865220680142318
Fancm ENSMUSG00000055884 0.952794070099461 0.952794070099461 0.707657842777675 0.952794070099461 0.632848414648752 0.952794070099461
Slx1b ENSMUSG00000059772 0.273102203263939 0.819306609791816 0.809671281226618 0.955923206999278 0.955923206999278 0.955923206999278
Eme2 ENSMUSG00000073436 0.484457700482441 0.794981788107556 0.84354063447501 0.84354063447501 0.52998785873837 0.794981788107556
2610002J02Rik ENSMUSG00000073684 0.0290901818140466 0.0872705454421397 0.0653888008597837 0.0980832012896756 0.616061269615089 0.616061269615089
Fancf ENSMUSG00000092118 0.214013296666816 0.478566931506538 0.319044621004358 0.478566931506538 0.629979851869174 0.629979851869174

Gap-filling DNA repair synthesis and ligation in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Xab2 ENSMUSG00000019470 0.244523124568126 0.596684608417104 0.596684608417104 0.596684608417104 0.406405668259231 0.596684608417104
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Ercc8 ENSMUSG00000021694 0.74021625136157 0.908879119821963 0.443434567388137 0.908879119821963 0.908879119821963 0.908879119821963
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Tcea1 ENSMUSG00000033813 0.168031151665548 0.47820935771585 0.318806238477233 0.47820935771585 0.984250407892614 0.984250407892614
Uvssa ENSMUSG00000037355 0.843558122902823 0.843558122902823 0.0514939454167058 0.154481836250118 0.569577029173232 0.843558122902823
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Aqr ENSMUSG00000040383 0.443400902865481 0.443400902865481 0.268094924132461 0.402142386198691 0.246425738661343 0.402142386198691
Hmgn1 ENSMUSG00000040681 0.452818511807821 0.679227767711731 0.317120263111731 0.679227767711731 0.883905269639111 0.883905269639111
Xrcc1 ENSMUSG00000051768 0.373889676064885 0.560834514097327 0.311472140296653 0.560834514097327 0.782330754853731 0.782330754853731
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

WNT5A-dependent internalization of FZD4

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539

PKMTs methylate histone lysines

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kmt2a ENSMUSG00000002028 0.386711600290463 0.580067400435694 0.222867123605114 0.580067400435694 0.899487218841682 0.899487218841682
Kmt2b ENSMUSG00000006307 0.450439130009804 0.675658695014706 0.232113578280582 0.675658695014706 0.918260520304179 0.918260520304179
Ehmt2 ENSMUSG00000013787 0.0994484416290466 0.29834532488714 0.943352337474371 0.943352337474371 0.760868514447969 0.943352337474371
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Ash1l ENSMUSG00000028053 0.378153132937169 0.722398003757208 0.594008023836612 0.722398003757208 0.722398003757208 0.722398003757208
Kmt2e ENSMUSG00000029004 0.289256842646334 0.590017198466378 0.393344798977585 0.590017198466378 0.887006238269199 0.887006238269199
Atf7ip ENSMUSG00000030213 0.749177881586968 0.984256550535308 0.984256550535308 0.984256550535308 0.675607826167175 0.984256550535308
Aebp2 ENSMUSG00000030232 0.977953534107396 0.981104927397305 0.399951668653518 0.981104927397305 0.981104927397305 0.981104927397305
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Setd6 ENSMUSG00000031671 0.218104872596431 0.654314617789292 0.862117320600689 0.862117320600689 0.681322032333544 0.862117320600689
Ehmt1 ENSMUSG00000036893 0.812779360307746 0.812779360307746 0.710559013815333 0.812779360307746 0.722378295159092 0.812779360307746
Setd1b ENSMUSG00000038384 0.632819760859843 0.749180399240644 0.404399824374705 0.749180399240644 0.749180399240644 0.749180399240644
Suv39h1 ENSMUSG00000039231 0.300114033243424 0.523179722078619 0.348786481385746 0.523179722078619 0.63563708959381 0.63563708959381
Setd1a ENSMUSG00000042308 0.990551896533929 0.990551896533929 0.593951684646498 0.990551896533929 0.82813213269717 0.990551896533929
Setd2 ENSMUSG00000044791 0.467313888562916 0.877651292404873 0.806647171702163 0.877651292404873 0.877651292404873 0.877651292404873
Suv420h1 ENSMUSG00000045098 0.352900406954565 0.616037846775787 0.591252934622595 0.616037846775787 0.616037846775787 0.616037846775787
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Whsc1l1 ENSMUSG00000054823 0.42248651259866 0.927659144367208 0.927659144367208 0.927659144367208 0.834289240651817 0.927659144367208
Smyd3 ENSMUSG00000055067 0.44579048970704 0.655523192190828 0.655523192190828 0.655523192190828 0.464914868467631 0.655523192190828
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Suv420h2 ENSMUSG00000059851 0.837383680330376 0.837383680330376 0.828142751254817 0.837383680330376 0.524887626690907 0.837383680330376
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Dot1l ENSMUSG00000061589 0.504435806113353 0.713518810138284 0.713518810138284 0.713518810138284 0.494387660202947 0.713518810138284
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Formation of the beta-catenin:TCF transactivating complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Tert ENSMUSG00000021611 0.81582851704757 0.81582851704757 0.701754634531338 0.81582851704757 0.397594673419908 0.81582851704757
Tle4 ENSMUSG00000024642 0.602224179001979 0.890139481950588 0.494410448307339 0.890139481950588 0.890139481950588 0.890139481950588
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rbbp5 ENSMUSG00000026439 0.313168893382181 0.809715763417819 0.809715763417819 0.809715763417819 0.646880085578186 0.809715763417819
Ash2l ENSMUSG00000031575 0.450197794650229 0.675296691975344 0.20526731212291 0.61580193636873 0.71924574173292 0.71924574173292
Smarca4 ENSMUSG00000032187 0.849696326784732 0.849696326784732 0.548305665060211 0.849696326784732 0.666897001517586 0.849696326784732
Bcl9 ENSMUSG00000038256 0.896373353412303 0.896373353412303 0.457666626209848 0.896373353412303 0.687144969868415 0.896373353412303
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Pygo2 ENSMUSG00000047824 0.627240891024233 0.868349262275774 0.101434829373398 0.304304488120195 0.868349262275774 0.868349262275774
Kmt2d ENSMUSG00000048154 0.275018695618127 0.444728148263227 0.296485432175484 0.444728148263227 0.955935485735632 0.955935485735632
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Bcl9l ENSMUSG00000063382 0.719441532431034 0.719441532431034 0.315129286028421 0.719441532431034 0.666880765429892 0.719441532431034

RNA Polymerase I Promoter Escape

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Rrn3 ENSMUSG00000022682 0.624339904317712 0.834266910855487 0.344792065919548 0.834266910855487 0.834266910855487 0.834266910855487
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

Cilium Assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Ift46 ENSMUSG00000002031 0.834159514292017 0.962209119240289 0.365060723987078 0.962209119240289 0.962209119240289 0.962209119240289
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tnpo1 ENSMUSG00000009470 0.494417786200833 0.788383945704149 0.788383945704149 0.788383945704149 0.687209982750423 0.788383945704149
Tctex1d2 ENSMUSG00000014075 0.797530635276862 0.797530635276862 0.770221240361777 0.797530635276862 0.797527494551165 0.797530635276862
Cluap1 ENSMUSG00000014232 0.369624870888318 0.921394225079788 0.773212463474045 0.921394225079788 0.921394225079788 0.921394225079788
Ift27 ENSMUSG00000016637 0.132011564794024 0.289019973601801 0.192679982401201 0.289019973601801 0.462485180772615 0.462485180772615
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ccdc41 ENSMUSG00000020024 0.0767204865353 0.2301614596059 0.359058162416547 0.538587243624821 0.737191999201571 0.737191999201571
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Exoc2 ENSMUSG00000021357 0.874544623073993 0.921406376481653 0.921406376481653 0.921406376481653 0.707632544124845 0.921406376481653
Cct5 ENSMUSG00000022234 0.862131161807723 0.862131161807723 0.417960895790413 0.862131161807723 0.652608573178535 0.862131161807723
Asap1 ENSMUSG00000022377 0.770211163763636 0.952793301476563 0.566942451615172 0.952793301476563 0.952793301476563 0.952793301476563
Cep97 ENSMUSG00000022604 0.373879244215948 0.949641223502237 0.949641223502237 0.949641223502237 0.74314391198049 0.949641223502237
Arl13b ENSMUSG00000022911 0.429415059628686 0.968520223112328 0.71353490001315 0.968520223112328 0.968520223112328 0.968520223112328
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Cep89 ENSMUSG00000023072 0.233559506921179 0.658347900312982 0.658347900312982 0.658347900312982 0.574934719901611 0.658347900312982
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Ift140 ENSMUSG00000024169 0.504257476172361 0.504257476172361 0.315280616140767 0.504257476172361 0.395296852347624 0.504257476172361
Tmem216 ENSMUSG00000024667 0.417854541537638 0.474624532646932 0.474624532646932 0.474624532646932 0.459977954546563 0.474624532646932
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Cct8 ENSMUSG00000025613 0.646901129062633 0.924533687312387 0.924533687312387 0.924533687312387 0.737203365937647 0.924533687312387
Pde6d ENSMUSG00000026239 0.794463171664167 0.794463171664167 0.00679151570218829 0.0203745471065649 0.758148459413747 0.794463171664167
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Ift80 ENSMUSG00000027778 0.72534600556455 0.72534600556455 0.594010085589296 0.72534600556455 0.519716686456954 0.72534600556455
Kif24 ENSMUSG00000028438 0.540447942857581 0.868345300482773 0.6756105600846 0.868345300482773 0.868345300482773 0.868345300482773
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mks1 ENSMUSG00000034121 0.133166636948269 0.399499910844806 0.719435229766814 0.719435229766814 0.602181528550136 0.719435229766814
Traf3ip1 ENSMUSG00000034292 1 1 0.28924954509742 0.86774863529226 0.940229426343187 1
Ttc21b ENSMUSG00000034848 0.580318590242206 0.88078455733909 0.88078455733909 0.88078455733909 0.604963066891069 0.88078455733909
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Bbs10 ENSMUSG00000035759 0.933951205228652 0.933951205228652 0.613291811915146 0.933951205228652 0.6469797881367 0.933951205228652
Bbs9 ENSMUSG00000035919 0.564241311190594 0.815820454637254 0.678483067359399 0.815820454637254 0.815820454637254 0.815820454637254
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Exoc1 ENSMUSG00000036435 0.415543130583432 0.770095312459101 0.770095312459101 0.770095312459101 0.56159350154872 0.770095312459101
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
C2cd3 ENSMUSG00000047248 0.489429390732886 0.604982556408182 0.138390379060489 0.415171137181468 0.604982556408182 0.604982556408182
Bbs12 ENSMUSG00000051444 0.61052689833357 0.764194744620874 0.764194744620874 0.764194744620874 0.436385723139687 0.764194744620874
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
4922501C03Rik ENSMUSG00000056919 0.675543696009354 0.908841494951936 0.908841494951936 0.908841494951936 0.785248613234626 0.908841494951936
Sclt1 ENSMUSG00000059834 0.749181725715864 0.837391361537029 0.837391361537029 0.837391361537029 0.613301726166376 0.837391361537029
Exoc5 ENSMUSG00000061244 0.108322260304065 0.324966780912195 0.355026060691986 0.532539091037979 0.921401924246316 0.921401924246316
Hspb11 ENSMUSG00000063172 0.572228089471274 0.782285388744571 0.782285388744571 0.782285388744571 0.287412100258045 0.782285388744571
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Tcp1 ENSMUSG00000068039 0.971656190495982 0.971656190495982 0.849725921700933 0.971656190495982 0.92451559146861 0.971656190495982
Exoc8 ENSMUSG00000074030 0.849737247415159 0.984252197087892 0.183285563776723 0.54985669133017 0.984252197087892 0.984252197087892
Bbip1 ENSMUSG00000084957 0.908868998529789 0.908868998529789 0.641192229278013 0.908868998529789 0.710527880564381 0.908868998529789

Loss of proteins required for interphase microtubule organization from the centrosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

Loss of Nlp from mitotic centrosomes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

Cell Cycle Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Cdc7 ENSMUSG00000029283 0.905754675088245 0.937088160291987 0.937088160291987 0.937088160291987 0.758177847489751 0.937088160291987
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Mdm4 ENSMUSG00000054387 0.24803855576882 0.372057833653231 0.233686246454199 0.372057833653231 0.479541919305052 0.479541919305052
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

RNA Pol II CTD phosphorylation and interaction with CE

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Supt5 ENSMUSG00000003435 0.588486627772475 0.882729941658713 0.38241770885624 0.882729941658713 0.949640571881925 0.949640571881925
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Rnmt ENSMUSG00000009535 0.359129912874267 0.69733372458093 0.46488914972062 0.69733372458093 0.743159222018627 0.743159222018627
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Rngtt ENSMUSG00000028274 0.0895432355691351 0.268629706707405 0.99055337452058 0.99055337452058 0.687173045570086 0.99055337452058
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Downstream signal transduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Rasa1 ENSMUSG00000021549 0.222896992458366 0.376945323539439 0.251296882359626 0.376945323539439 0.825080354293345 0.825080354293345
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Nck2 ENSMUSG00000066877 0.695886060438501 0.773225423434546 0.393349353627609 0.773225423434546 0.773225423434546 0.773225423434546

Transport to the Golgi and subsequent modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Man1a2 ENSMUSG00000008763 0.330822217752787 0.877668439988077 0.71351773942311 0.877668439988077 0.877668439988077 0.877668439988077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Fut8 ENSMUSG00000021065 0.800516224830663 0.933931185203149 0.933931185203149 0.933931185203149 0.504470362618556 0.933931185203149
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
B4galt4 ENSMUSG00000022793 0.556279987782527 0.846657138693467 0.803630539662222 0.846657138693467 0.846657138693467 0.846657138693467
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Mgat5 ENSMUSG00000036155 0.61329363619444 0.927676688706274 0.927676688706274 0.927676688706274 0.773241361632843 0.927676688706274
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Manea ENSMUSG00000040520 0.328803574646066 0.455025853771683 0.316806879814107 0.455025853771683 0.455025853771683 0.455025853771683
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
B4galt3 ENSMUSG00000052423 0.555852678813415 0.833779018220122 0.981105507625407 0.981105507625407 0.481717689407786 0.833779018220122
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902

Deadenylation of mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cnot11 ENSMUSG00000003135 0.880767153430928 0.880767153430928 0.143640644888863 0.43092193466659 0.815834234857318 0.880767153430928
Cnot2 ENSMUSG00000020166 0.243179186795457 0.364768780193186 0.158554586460091 0.364768780193186 0.553559339976067 0.553559339976067
Cnot6 ENSMUSG00000020362 0.613249925729333 0.834301003948448 0.834301003948448 0.834301003948448 0.734252715169967 0.834301003948448
Cnot8 ENSMUSG00000020515 0.276667940777377 0.276667940777377 0.0535076950740595 0.160523085222178 0.261241889280451 0.276667940777377
Eif4a2 ENSMUSG00000022884 0.776262606175218 0.794463575615136 0.509527671271441 0.794463575615136 0.794463575615136 0.794463575615136
Eif4a3 ENSMUSG00000025580 0.171760548745426 0.257640823118139 0.0491239464846142 0.147371839453843 0.707524265318445 0.707524265318445
Rqcd1 ENSMUSG00000026174 0.61605724781529 0.924085871722935 0.399975300566113 0.924085871722935 0.981106608856826 0.981106608856826
Pan3 ENSMUSG00000029647 0.655456393746432 0.849722654511013 0.524801691324984 0.849722654511013 0.849722654511013 0.849722654511013
Tnks1bp1 ENSMUSG00000033955 0.342754584646485 0.915129096871031 0.661206427741987 0.915129096871031 0.915129096871031 0.915129096871031
Zcchc11 ENSMUSG00000034610 0.871429201699317 0.927668208119842 0.448129353121277 0.927668208119842 0.927668208119842 0.927668208119842
Cnot3 ENSMUSG00000035632 0.69885299223171 0.940224130655848 0.728315918684505 0.940224130655848 0.940224130655848 0.940224130655848
Cnot4 ENSMUSG00000038784 0.058681017107145 0.176043051321435 0.602147593213125 0.602147593213125 0.519613565985356 0.602147593213125
Eif4g1 ENSMUSG00000045983 0.704452523787093 0.704452523787093 0.00661908700990114 0.0198572610297034 0.652402315216755 0.704452523787093
Cnot10 ENSMUSG00000056167 0.429404991207125 0.761182690769245 0.761182690769245 0.761182690769245 0.641297400981759 0.761182690769245

Processing of Capped Intronless Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Papola ENSMUSG00000021111 0.142625197416278 0.427875592248835 0.915134790164448 0.99685047951358 0.99685047951358 0.99685047951358
Pabpn1 ENSMUSG00000022194 0.66958204480997 0.896349458650251 0.877610787359369 0.896349458650251 0.896349458650251 0.896349458650251
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sympk ENSMUSG00000023118 0.529683992169126 0.684073598352468 0.422390480968457 0.684073598352468 0.684073598352468 0.684073598352468
Cstf3 ENSMUSG00000027176 0.59671661107049 0.627208449391029 0.627208449391029 0.627208449391029 0.519702025695241 0.627208449391029
Snrpb ENSMUSG00000027404 0.124788112396534 0.187154405862 0.00181845540865975 0.00545536622597925 0.187154405862 0.187154405862
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Fip1l1 ENSMUSG00000029227 0.469695621340657 0.800579427986739 0.800579427986739 0.800579427986739 0.658330451648748 0.800579427986739
Cpsf4 ENSMUSG00000029625 0.413365652549691 0.930812844017045 0.899496608250514 0.930812844017045 0.930812844017045 0.930812844017045
Nudt21 ENSMUSG00000031754 0.298341610654406 0.895024831963218 0.955937166685996 0.955937166685996 0.849723185236561 0.955937166685996
Cpsf1 ENSMUSG00000034022 0.13821339752582 0.207320096288731 0.0902515816291753 0.207320096288731 0.514369965274496 0.514369965274496
Cpsf7 ENSMUSG00000034820 0.933949645498227 0.933949645498227 0.924541533483335 0.933949645498227 0.67850361593939 0.933949645498227
Cpsf2 ENSMUSG00000041781 0.624414744759693 0.91200099736939 0.91200099736939 0.91200099736939 0.893243013266494 0.91200099736939
Lsm11 ENSMUSG00000044847 0.436363548388505 0.654545322582758 0.219769748508287 0.654545322582758 0.692921430693931 0.692921430693931
Cstf2t ENSMUSG00000053536 0.311431580943726 0.803586684891559 0.803586684891559 0.803586684891559 0.610398798514298 0.803586684891559
Cpsf3 ENSMUSG00000054309 0.404370943580145 0.404370943580145 0.124102194188422 0.320923349306029 0.213948899537352 0.320923349306029

RNA Polymerase I Transcription Termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.0239146347335665 0.0717439042006994 0.110035741129492 0.165053611694239 0.382424476320608 0.382424476320608
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Gtf2h2 ENSMUSG00000021639 0.924529343143857 0.924529343143857 0.588481499887436 0.924529343143857 0.737219678303839 0.924529343143857
Ercc3 ENSMUSG00000024382 0.311110719442708 0.466666079164062 0.16447887006899 0.466666079164062 0.618529974160891 0.618529974160891
Ttf1 ENSMUSG00000026803 0.908825577532465 0.908825577532465 0.828000427650926 0.908825577532465 0.852761801626285 0.908825577532465
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Ercc2 ENSMUSG00000030400 0.296529667204614 0.44479450080692 0.218448425150286 0.44479450080692 0.710593656288175 0.710593656288175
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

Nuclear Envelope Breakdown

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

KSRP (KHSRP) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Khsrp ENSMUSG00000007670 0.837321743303952 0.921404784610143 0.921404784610143 0.921404784610143 0.862068813004363 0.921404784610143
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388

Synthesis of PIPs at the Golgi membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965
Pi4kb ENSMUSG00000038861 0.785002570027176 0.809512890262261 0.519502292050506 0.809512890262261 0.809512890262261 0.809512890262261
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053

PTEN Regulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Maf1 ENSMUSG00000022553 0.232078311401733 0.3481174671026 0.00785414401890984 0.0235624320567295 0.899487598488328 0.899487598488328
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Mkrn1 ENSMUSG00000029922 0.216490221537255 0.324735332305882 0.118244827676101 0.324735332305882 0.61016482119888 0.61016482119888
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Wwp2 ENSMUSG00000031930 0.321026297928993 0.321026297928993 0.109221743718641 0.321026297928993 0.302058762011907 0.321026297928993
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

PIP3 activates AKT signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Kit ENSMUSG00000005672 0.843522864090151 0.843522864090151 0.764189096979214 0.843522864090151 0.785324030328461 0.843522864090151
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Maf1 ENSMUSG00000022553 0.232078311401733 0.3481174671026 0.00785414401890984 0.0235624320567295 0.899487598488328 0.899487598488328
Strn ENSMUSG00000024077 0.393265129458563 0.987400303068685 0.981106423222112 0.987400303068685 0.987400303068685 0.987400303068685
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Mkrn1 ENSMUSG00000029922 0.216490221537255 0.324735332305882 0.118244827676101 0.324735332305882 0.61016482119888 0.61016482119888
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Phlpp2 ENSMUSG00000031732 0.840472980521873 0.840472980521873 0.479525407473586 0.719288111210379 0.420200818877701 0.719288111210379
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Wwp2 ENSMUSG00000031930 0.321026297928993 0.321026297928993 0.109221743718641 0.321026297928993 0.302058762011907 0.321026297928993
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617

Rab regulation of trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rin2 ENSMUSG00000001768 0.877666542586628 0.877666542586628 0.73399696152476 0.877666542586628 0.386418764761682 0.877666542586628
Gdi1 ENSMUSG00000015291 0.97796043059637 0.97796043059637 0.484431605352091 0.726647408028137 0.350907015843479 0.726647408028137
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Trappc12 ENSMUSG00000020628 0.443387078271416 0.443387078271416 0.19006612444106 0.443387078271416 0.438716878108443 0.443387078271416
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Trappc13 ENSMUSG00000021711 0.094972509193824 0.284917527581472 0.378120241073486 0.567180361610229 0.613294786270333 0.613294786270333
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Gapvd1 ENSMUSG00000026867 0.69300453924434 0.69300453924434 0.340587538987273 0.69300453924434 0.489343980904243 0.69300453924434
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Trappc8 ENSMUSG00000033382 0.138229469212802 0.414688407638407 0.949638566305517 0.949638566305517 0.604694278613409 0.907041417920113
Tbc1d10a ENSMUSG00000034412 0.602137687009539 0.740181369489312 0.45756491055059 0.740181369489312 0.740181369489312 0.740181369489312
Ankrd27 ENSMUSG00000034867 0.569569563592984 0.627210181364254 0.348839987958392 0.627210181364254 0.627210181364254 0.627210181364254
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Trappc11 ENSMUSG00000038102 0.740092016826772 0.740092016826772 0.457621085091718 0.740092016826772 0.629928919607601 0.740092016826772
Sbf2 ENSMUSG00000038371 0.908873953217301 0.908873953217301 0.890136154521336 0.908873953217301 0.35705797334954 0.908873953217301
Tbc1d17 ENSMUSG00000038520 0.10144889267115 0.304346678013449 0.313373449998798 0.470060174998197 0.79137614013413 0.79137614013413
Tbc1d25 ENSMUSG00000039201 0.402038402236954 0.830350784447286 0.553567189631524 0.830350784447286 0.883879804882268 0.883879804882268
Tbc1d2 ENSMUSG00000039813 0.354999710776454 0.651064940968246 0.434043293978831 0.651064940968246 0.896375251853633 0.896375251853633
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Hps4 ENSMUSG00000042328 0.464810672479667 0.632782508531239 0.113690003833535 0.341070011500605 0.632782508531239 0.632782508531239
Tbc1d10b ENSMUSG00000042492 0.362986514683911 0.544479772025867 0.328794307304242 0.544479772025867 0.757959235020951 0.757959235020951
Dennd4a ENSMUSG00000053641 0.506787812327301 0.768006652621308 0.98425081610098 0.98425081610098 0.512004435080872 0.768006652621308
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Mon1b ENSMUSG00000078908 0.77626936738718 0.977961380140919 0.785360586740878 0.977961380140919 0.977961380140919 0.977961380140919
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106

AURKA Activation by TPX2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

RNA Polymerase III Transcription Initiation From Type 3 Promoter

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Snapc2 ENSMUSG00000011837 0.074077786507793 0.111116679761689 0.0285767095373537 0.085730128612061 0.809731584299906 0.809731584299906
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Snapc1 ENSMUSG00000021113 0.506889229835954 0.971660959592701 0.971660959592701 0.971660959592701 0.740164944692337 0.971660959592701
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Pou2f1 ENSMUSG00000026565 0.649767827222401 0.918265122912518 0.684298191478122 0.918265122912518 0.918265122912518 0.918265122912518
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Snapc3 ENSMUSG00000028483 0.436126498132501 0.740070616743833 0.740070616743833 0.740070616743833 0.511989283403657 0.740070616743833
Snapc4 ENSMUSG00000036281 0.438553454597893 0.899438510249629 0.899438510249629 0.899438510249629 0.883904046992797 0.899438510249629
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806

Retrograde transport at the Trans-Golgi-Network

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Vps53 ENSMUSG00000017288 0.377941116190403 0.566911674285605 0.0918141240913908 0.275442372274172 0.974802785331107 0.974802785331107
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Vps52 ENSMUSG00000024319 0.621367928119512 0.788281082479196 0.357097229975649 0.788281082479196 0.788281082479196 0.788281082479196
Vps51 ENSMUSG00000024797 0.105653507029143 0.310135981870419 0.206757321246946 0.310135981870419 0.38454930818886 0.38454930818886
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Golga1 ENSMUSG00000026754 0.211073540781294 0.316610311171941 0.158430081793005 0.316610311171941 0.43174020429507 0.43174020429507
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Gcc1 ENSMUSG00000029708 0.464741208485198 0.698842272802265 0.698842272802265 0.698842272802265 0.613122438466004 0.698842272802265
Tmf1 ENSMUSG00000030059 0.0268244330294316 0.080473299088295 0.469722256882648 0.704583385323973 0.946493484550472 0.946493484550472
Arfip2 ENSMUSG00000030881 0.968488970040684 0.968488970040684 0.672464777544939 0.968488970040684 0.655477247667167 0.968488970040684
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Arfrp1 ENSMUSG00000038671 0.320994413286289 0.481491619929434 0.122042650948381 0.366127952845144 0.749059059663526 0.749059059663526
Sys1 ENSMUSG00000045503 0.0152643007233324 0.0228964510849985 0.00330599018088915 0.00991797054266744 0.821986076879709 0.821986076879709
Arl1 ENSMUSG00000060904 0.977954922786188 0.977954922786188 0.883883578019259 0.977954922786188 0.369504346512649 0.977954922786188
Rabepk ENSMUSG00000070953 0.230468444889404 0.345702667334107 0.113689596861401 0.341068790584202 0.49433381603067 0.49433381603067

Nuclear Events (kinase and transcription factor activation)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Nab2 ENSMUSG00000025402 0.499393542731024 0.974814176831575 0.707644882711197 0.974814176831575 0.974814176831575 0.974814176831575
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Egr2 ENSMUSG00000037868 0.48859656608548 0.573870218118701 0.552913061760835 0.573870218118701 0.573870218118701 0.573870218118701
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624

Mitotic Spindle Checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589

RAB GEFs exchange GTP for GDP on RABs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rin2 ENSMUSG00000001768 0.877666542586628 0.877666542586628 0.73399696152476 0.877666542586628 0.386418764761682 0.877666542586628
Gdi1 ENSMUSG00000015291 0.97796043059637 0.97796043059637 0.484431605352091 0.726647408028137 0.350907015843479 0.726647408028137
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Trappc12 ENSMUSG00000020628 0.443387078271416 0.443387078271416 0.19006612444106 0.443387078271416 0.438716878108443 0.443387078271416
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Trappc13 ENSMUSG00000021711 0.094972509193824 0.284917527581472 0.378120241073486 0.567180361610229 0.613294786270333 0.613294786270333
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Gapvd1 ENSMUSG00000026867 0.69300453924434 0.69300453924434 0.340587538987273 0.69300453924434 0.489343980904243 0.69300453924434
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Trappc8 ENSMUSG00000033382 0.138229469212802 0.414688407638407 0.949638566305517 0.949638566305517 0.604694278613409 0.907041417920113
Ankrd27 ENSMUSG00000034867 0.569569563592984 0.627210181364254 0.348839987958392 0.627210181364254 0.627210181364254 0.627210181364254
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Trappc11 ENSMUSG00000038102 0.740092016826772 0.740092016826772 0.457621085091718 0.740092016826772 0.629928919607601 0.740092016826772
Sbf2 ENSMUSG00000038371 0.908873953217301 0.908873953217301 0.890136154521336 0.908873953217301 0.35705797334954 0.908873953217301
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Hps4 ENSMUSG00000042328 0.464810672479667 0.632782508531239 0.113690003833535 0.341070011500605 0.632782508531239 0.632782508531239
Dennd4a ENSMUSG00000053641 0.506787812327301 0.768006652621308 0.98425081610098 0.98425081610098 0.512004435080872 0.768006652621308
Mon1b ENSMUSG00000078908 0.77626936738718 0.977961380140919 0.785360586740878 0.977961380140919 0.977961380140919 0.977961380140919
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106

Golgi-to-ER retrograde transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pafah1b3 ENSMUSG00000005447 0.429431168017631 0.687130134373971 0.687130134373971 0.687130134373971 0.627161792520192 0.687130134373971
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Kif19a ENSMUSG00000010021 0.707571700801429 0.809347792166954 0.754701535164911 0.809347792166954 0.809347792166954 0.809347792166954
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Nbas ENSMUSG00000020576 0.831199458852206 0.831199458852206 0.0753846720564074 0.226154016169222 0.247920106909697 0.371880160364545
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Bnip1 ENSMUSG00000024191 0.0346582671987526 0.0709621643207598 0.0473081095471732 0.0709621643207598 0.489381298258457 0.489381298258457
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Rint1 ENSMUSG00000028999 0.937073603772649 0.937073603772649 0.422451096973321 0.937073603772649 0.852843783462489 0.937073603772649
Stx18 ENSMUSG00000029125 0.309581512482546 0.737857261122885 0.927674707753686 0.927674707753686 0.49190484074859 0.737857261122885
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Kif9 ENSMUSG00000032489 0.852651985562056 0.95277494340192 0.95277494340192 0.95277494340192 0.893051561758697 0.95277494340192
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Bicd2 ENSMUSG00000037933 0.188558410070277 0.422937960694121 0.281958640462747 0.422937960694121 0.692946871935085 0.692946871935085
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Kif13b ENSMUSG00000060012 0.825065979446263 0.825065979446263 0.758155212029761 0.825065979446263 0.649810810611423 0.825065979446263
Kif27 ENSMUSG00000060176 0.90794064172691 0.974602699673214 0.583115579423678 0.974602699673214 0.974602699673214 0.974602699673214
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298

Inactivation of APC/C via direct inhibition of the APC/C complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589

Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589

Synthesis of PIPs at the early endosome membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Pi4k2a ENSMUSG00000025178 0.152546791070185 0.228820186605277 0.0279945654777242 0.0839836964331727 0.59669794377838 0.59669794377838
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965
Mtmr12 ENSMUSG00000039458 0.800578883012737 0.800578883012737 0.464902733669432 0.697354100504148 0.352960263597269 0.697354100504148

Regulation of PTEN gene transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Maf1 ENSMUSG00000022553 0.232078311401733 0.3481174671026 0.00785414401890984 0.0235624320567295 0.899487598488328 0.899487598488328
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857

Separation of Sister Chromatids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Hdac8 ENSMUSG00000067567 0.635674317546918 0.865242725916753 0.865242725916753 0.865242725916753 0.862137379847626 0.865242725916753
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Glycolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Pgam1 ENSMUSG00000011752 0.852801192111818 0.852801192111818 0.201046044735963 0.60313813420789 0.818870648703071 0.852801192111818
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Pfkfb1 ENSMUSG00000025271 0.588492130656257 0.882738195984386 0.38406707812773 0.882738195984386 0.905667774593432 0.905667774593432
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Gnpda2 ENSMUSG00000029209 0.106379091118 0.182461971255547 0.121641314170365 0.182461971255547 0.905674432244613 0.905674432244613
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Bpgm ENSMUSG00000038871 0.582227323512959 0.930582178794828 0.803306944610457 0.930582178794828 0.930582178794828 0.930582178794828
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Eno1 ENSMUSG00000063524 0.564113347358687 0.564113347358687 0.242910138014227 0.538403804399347 0.358935869599564 0.538403804399347
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

MET receptor recycling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Gga3 ENSMUSG00000020740 0.431661296064648 0.647491944096972 0.427127348199379 0.647491944096972 0.818918522508069 0.818918522508069
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Rab4b ENSMUSG00000053291 0.484474264461291 0.613292882690895 0.613292882690895 0.613292882690895 0.496911756913925 0.613292882690895
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166

Synthesis of PIPs at the late endosome membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vac14 ENSMUSG00000010936 0.550983775340078 0.826475663010117 0.0329132325350589 0.0987396976051768 0.940225662886198 0.940225662886198
Mtmr4 ENSMUSG00000018401 0.616016746788836 0.921389053119371 0.168186513259422 0.504559539778265 0.921389053119371 0.921389053119371
Pikfyve ENSMUSG00000025949 0.268046833901181 0.593345367607294 0.395563578404863 0.593345367607294 0.899492678639784 0.899492678639784
Mtmr2 ENSMUSG00000031918 0.0513712673827628 0.154113802148289 0.9433587423069 0.9433587423069 0.698784976465742 0.9433587423069
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Fig4 ENSMUSG00000038417 0.382472215464334 0.5737083231965 0.915126226185809 0.915126226185809 0.280202728636499 0.5737083231965

Processing and activation of SUMO

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Sumo3 ENSMUSG00000020265 0.408670387543105 0.987403934713771 0.987403934713771 0.987403934713771 0.849712304238851 0.987403934713771
Senp5 ENSMUSG00000022772 0.322987682059722 0.803627553914552 0.803627553914552 0.803627553914552 0.627228423353243 0.803627553914552
Senp2 ENSMUSG00000022855 0.318959073507393 0.523070923993142 0.348713949328761 0.523070923993142 0.924493561362545 0.924493561362545
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435

ESR-mediated signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Ppp5c ENSMUSG00000003099 0.734155957610943 0.855937200255394 0.855937200255394 0.855937200255394 0.754985282103299 0.855937200255394
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Cdk9 ENSMUSG00000009555 0.602224057278943 0.809743233783875 0.630039061512395 0.809743233783875 0.809743233783875 0.809743233783875
Ccnt1 ENSMUSG00000011960 0.127022835080564 0.381068505241693 0.455260797441782 0.682891196162673 0.955917824133995 0.955917824133995
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Med1 ENSMUSG00000018160 0.176912994511997 0.530738983535992 0.937088643933494 0.937088643933494 0.690096905754397 0.937088643933494
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Gtf2a1 ENSMUSG00000020962 0.927676592078217 0.968520560323564 0.695946712031778 0.968520560323564 0.968520560323564 0.968520560323564
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Strn ENSMUSG00000024077 0.393265129458563 0.987400303068685 0.981106423222112 0.987400303068685 0.987400303068685 0.987400303068685
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Usf1 ENSMUSG00000026641 0.154950910575402 0.246808064186286 0.164538709457524 0.246808064186286 0.693016648185862 0.693016648185862
Uhmk1 ENSMUSG00000026667 0.672737467642922 0.99055395349967 0.553621771051132 0.99055395349967 0.99055395349967 0.99055395349967
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Gnb4 ENSMUSG00000027669 0.896378254629603 0.896378254629603 0.719429887176208 0.896378254629603 0.58855098108693 0.896378254629603
Ppid ENSMUSG00000027804 0.0956899952809215 0.287069985842764 0.940221845415162 0.940221845415162 0.849732173546496 0.940221845415162
Zdhhc21 ENSMUSG00000028403 0.641180479809691 0.961770719714536 0.35281641907237 0.961770719714536 0.977957440943633 0.977957440943633
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Gnb1 ENSMUSG00000029064 0.752112227583879 0.752112227583879 0.424800141460724 0.752112227583879 0.635590066427997 0.752112227583879
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Gnb2 ENSMUSG00000029713 0.014591268837441 0.0218869032561615 0.0119929612037782 0.0218869032561615 0.924500360031433 0.924500360031433
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Carm1 ENSMUSG00000032185 0.672407698617612 0.990552795435014 0.990552795435014 0.990552795435014 0.7340345327491 0.990552795435014
Gnai2 ENSMUSG00000032562 0.764147302047563 0.828140918654959 0.302010370080407 0.828140918654959 0.828140918654959 0.828140918654959
Greb1 ENSMUSG00000036523 0.443613769058974 0.443613769058974 0.220748142268246 0.443613769058974 0.371677077665633 0.443613769058974
Kdm1a ENSMUSG00000036940 0.561448376444258 0.842172564666387 0.450458492275885 0.842172564666387 0.968508927302806 0.968508927302806
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Gng10 ENSMUSG00000038607 0.779298584363925 0.89325835750727 0.89325835750727 0.89325835750727 0.369641003660815 0.89325835750727
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Gng2 ENSMUSG00000043004 0.803607853159088 0.803607853159088 0.746086303777471 0.803607853159088 0.30193486428631 0.803607853159088
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Usf2 ENSMUSG00000058239 0.713542485174276 0.713542485174276 0.238418758708314 0.713542485174276 0.630027780207552 0.713542485174276
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Gng8 ENSMUSG00000063594 0.644090126802365 0.649764722457812 0.649764722457812 0.649764722457812 0.455188806742285 0.649764722457812
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ptges3 ENSMUSG00000071072 0.794466403205246 0.794466403205246 0.0539401077163417 0.161820323149025 0.596673651918825 0.794466403205246
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

Attachment of GPI anchor to uPAR

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pigt ENSMUSG00000017721 0.698534474020628 0.752174519354127 0.752174519354127 0.752174519354127 0.618477155240358 0.752174519354127
Gpaa1 ENSMUSG00000022561 0.140166511072528 0.210249766608792 0.0554643222446901 0.16639296673407 0.41514481101606 0.41514481101606
Pigu ENSMUSG00000038383 0.176926134305675 0.530778402917025 0.883880384398204 0.883880384398204 0.610420955622581 0.883880384398204
Pigk ENSMUSG00000039047 0.758182007536299 0.758182007536299 0.62163877745223 0.758182007536299 0.719426675472166 0.758182007536299
Pigs ENSMUSG00000041958 0.420220167764266 0.630330251646399 0.141622561647642 0.424867684942927 0.984256431021961 0.984256431021961
Pgap1 ENSMUSG00000073678 0.434024879763406 0.818907750235861 0.553616938893275 0.818907750235861 0.818907750235861 0.818907750235861

RNA Polymerase III Transcription Initiation From Type 1 Promoter

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Gtf3a ENSMUSG00000016503 0.101848345269951 0.152772517904927 0.0141417890799713 0.0424253672399139 0.977930494027345 0.977930494027345
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Gtf3c5 ENSMUSG00000026816 0.240001081265092 0.360001621897639 0.209608182047211 0.360001621897639 0.8036268665289 0.8036268665289
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Gtf3c1 ENSMUSG00000032777 0.514477384975409 0.771716077463113 0.326830323471223 0.771716077463113 0.990549428512413 0.990549428512413
Gtf3c4 ENSMUSG00000035666 0.984256165622295 0.984256165622295 0.162099658146484 0.486298974439453 0.921405886685337 0.984256165622295
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Gtf3c3 ENSMUSG00000041303 0.482006439491822 0.704726334199839 0.212555196216459 0.637665588649376 0.704726334199839 0.704726334199839
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806

Asparagine N-linked glycosylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Man1a2 ENSMUSG00000008763 0.330822217752787 0.877668439988077 0.71351773942311 0.877668439988077 0.877668439988077 0.877668439988077
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Dhdds ENSMUSG00000012117 0.380096767525911 0.486885228563667 0.156177897574698 0.468533692724093 0.486885228563667 0.486885228563667
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Fut8 ENSMUSG00000021065 0.800516224830663 0.933931185203149 0.933931185203149 0.933931185203149 0.504470362618556 0.933931185203149
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
B4galt4 ENSMUSG00000022793 0.556279987782527 0.846657138693467 0.803630539662222 0.846657138693467 0.846657138693467 0.846657138693467
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Dpm2 ENSMUSG00000026810 0.324494861834532 0.50685771288579 0.50685771288579 0.50685771288579 0.365213878733351 0.50685771288579
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Slc35a1 ENSMUSG00000028293 0.499420937815872 0.749131406723807 0.268064332008418 0.749131406723807 0.962229010589356 0.962229010589356
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Vcp ENSMUSG00000028452 0.0236639774182962 0.0354959661274443 1.47174678044764e-05 4.41524034134291e-05 0.431715932233461 0.431715932233461
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Glt28d2 ENSMUSG00000031286 0.831144980850077 0.949621753864074 0.949621753864074 0.949621753864074 0.678099586980704 0.949621753864074
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Amfr ENSMUSG00000031751 0.160598941935287 0.24089841290293 0.00166099377824492 0.00498298133473477 0.98739575239825 0.98739575239825
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Alg9 ENSMUSG00000032059 0.865216430727327 0.865216430727327 0.0872328677294176 0.261698603188253 0.728305688303467 0.865216430727327
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Fuk ENSMUSG00000033703 0.202504121652905 0.303756182479357 0.110117431939355 0.303756182479357 0.831224840369681 0.831224840369681
Alg3 ENSMUSG00000033809 0.0337267523379115 0.0545486602768248 0.0363657735178832 0.0545486602768248 0.454677354933429 0.454677354933429
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Nagk ENSMUSG00000034744 0.132873937161566 0.398621811484697 0.58561417216832 0.644087090424569 0.644087090424569 0.644087090424569
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Mgat5 ENSMUSG00000036155 0.61329363619444 0.927676688706274 0.927676688706274 0.927676688706274 0.773241361632843 0.927676688706274
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Alg1 ENSMUSG00000039427 0.238169764923128 0.238169764923128 0.0288573539356085 0.0865720618068256 0.213940154501969 0.238169764923128
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Manea ENSMUSG00000040520 0.328803574646066 0.455025853771683 0.316806879814107 0.455025853771683 0.455025853771683 0.455025853771683
St8sia4 ENSMUSG00000040710 0.818878583905477 0.965369500416752 0.965369500416752 0.965369500416752 0.585685930180055 0.965369500416752
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
B4galt3 ENSMUSG00000052423 0.555852678813415 0.833779018220122 0.981105507625407 0.981105507625407 0.481717689407786 0.833779018220122
St6galnac3 ENSMUSG00000052544 0.457673821176896 0.686510731765344 0.927671188342965 0.927671188342965 0.246407613661978 0.686510731765344
Fpgt ENSMUSG00000053870 0.290907432114314 0.50798959574374 0.338659730495827 0.50798959574374 0.755157091765088 0.755157091765088
Nanp ENSMUSG00000053916 0.874426704515627 0.987391425325871 0.987391425325871 0.987391425325871 0.286465426520232 0.859396279560696
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902
Alg6 ENSMUSG00000073792 0.968509806380037 0.968509806380037 0.902606179045671 0.968509806380037 0.548297525238618 0.968509806380037
Dolk ENSMUSG00000075419 0.0148011689873284 0.0148011689873284 2.65654703682613e-05 7.96964111047838e-05 0.0119531327006982 0.0148011689873284
Dpm1 ENSMUSG00000078919 0.0409862603823654 0.0614793905735481 0.0180882720006123 0.0542648160018368 0.937087214004604 0.937087214004604
Gm20716 ENSMUSG00000093752 0.83425163601779 0.83425163601779 0.545583608319016 0.83425163601779 0.7431635404496 0.83425163601779

Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Ppp5c ENSMUSG00000003099 0.734155957610943 0.855937200255394 0.855937200255394 0.855937200255394 0.754985282103299 0.855937200255394
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Eya2 ENSMUSG00000017897 0.883900275850861 0.883900275850861 0.574973102444853 0.883900275850861 0.868343217484915 0.883900275850861
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Eya3 ENSMUSG00000028886 0.354939940500405 0.499334371435975 0.438729069044625 0.499334371435975 0.499334371435975 0.499334371435975
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

Vesicle-mediated transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Hip1r ENSMUSG00000000915 0.545683876865408 0.996850730657377 0.974810147975717 0.996850730657377 0.996850730657377 0.996850730657377
Sec24b ENSMUSG00000001052 0.779277190298091 0.902615562587447 0.902615562587447 0.902615562587447 0.896361822454715 0.902615562587447
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rin2 ENSMUSG00000001768 0.877666542586628 0.877666542586628 0.73399696152476 0.877666542586628 0.386418764761682 0.877666542586628
Ap4e1 ENSMUSG00000001998 0.865244022390156 0.865244022390156 0.537859075080974 0.865244022390156 0.632859091603956 0.865244022390156
Golga2 ENSMUSG00000002546 0.454829493303593 0.695937547219021 0.695937547219021 0.695937547219021 0.643726841105242 0.695937547219021
Ykt6 ENSMUSG00000002741 0.134922482435751 0.261624486285198 0.174416324190132 0.261624486285198 0.695710453975502 0.695710453975502
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Ap1m1 ENSMUSG00000003033 0.852763396074851 0.852763396074851 0.460085037463511 0.852763396074851 0.5694284648412 0.852763396074851
Sh3gl1 ENSMUSG00000003200 0.734257170446249 0.734257170446249 0.404418970770285 0.606628456155427 0.397733389607841 0.606628456155427
Cyth2 ENSMUSG00000003269 0.809458323857289 0.809458323857289 0.195055626146888 0.585166878440664 0.742913793732197 0.809458323857289
Ap1s1 ENSMUSG00000004849 0.599494473380636 0.899241710070954 0.338774886348955 0.899241710070954 0.996851223624921 0.996851223624921
Ubqln1 ENSMUSG00000005312 0.886984660793428 0.886984660793428 0.201083689829996 0.603251069489988 0.764118582319767 0.886984660793428
Pafah1b3 ENSMUSG00000005447 0.429431168017631 0.687130134373971 0.687130134373971 0.687130134373971 0.627161792520192 0.687130134373971
Bloc1s6 ENSMUSG00000005804 0.731244815731594 0.731244815731594 0.123057122168857 0.36917136650657 0.273190456560293 0.409785684840439
Napa ENSMUSG00000006024 0.30522101420907 0.457831521313605 0.877629525603277 0.877629525603277 0.276133242979892 0.457831521313605
Snf8 ENSMUSG00000006058 0.012863396720729 0.0192950950810935 0.00170650025632417 0.00511950076897252 0.824991011420563 0.824991011420563
Eps15l1 ENSMUSG00000006276 0.785251119050755 0.785251119050755 0.666888813786863 0.785251119050755 0.731161645452711 0.785251119050755
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Ap1b1 ENSMUSG00000009090 0.350802381985732 0.526203572978598 0.0525017105892906 0.157505131767872 0.621585745224902 0.621585745224902
Kif19a ENSMUSG00000010021 0.707571700801429 0.809347792166954 0.754701535164911 0.809347792166954 0.809347792166954 0.809347792166954
Tmem115 ENSMUSG00000010045 0.0981288023186614 0.147193203477992 0.0025900291314006 0.00777008739420181 0.450467412433576 0.450467412433576
Stx5a ENSMUSG00000010110 0.501831767413938 0.678403955905927 0.678403955905927 0.678403955905927 0.496797370510828 0.678403955905927
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Gosr1 ENSMUSG00000010392 0.110762431488893 0.33228729446668 0.40651774588839 0.609776618832584 0.794464450834067 0.794464450834067
Tsg101 ENSMUSG00000014402 0.202477913474612 0.607433740423835 0.949645396642883 0.949645396642883 0.638440217186756 0.949645396642883
Gdi1 ENSMUSG00000015291 0.97796043059637 0.97796043059637 0.484431605352091 0.726647408028137 0.350907015843479 0.726647408028137
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Cnih1 ENSMUSG00000015759 0.962218354049019 0.962218354049019 0.0902461701192333 0.2707385103577 0.924520963585995 0.962218354049019
Pacsin2 ENSMUSG00000016664 0.770104729886689 0.849665402660967 0.0513047073248464 0.153914121974539 0.849665402660967 0.849665402660967
Cyth1 ENSMUSG00000017132 0.758149270804472 0.852814813665325 0.852814813665325 0.852814813665325 0.701671796091141 0.852814813665325
Vps53 ENSMUSG00000017288 0.377941116190403 0.566911674285605 0.0918141240913908 0.275442372274172 0.974802785331107 0.974802785331107
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Cyth3 ENSMUSG00000018001 0.303893766999886 0.577553176571601 0.577553176571601 0.577553176571601 0.429278601040177 0.577553176571601
Cog1 ENSMUSG00000018661 0.435845407867745 0.660742333882329 0.621331497669603 0.660742333882329 0.660742333882329 0.660742333882329
Copz2 ENSMUSG00000018672 0.0642471788017493 0.096370768202624 0.0236760489133853 0.0710281467401559 0.815855606264524 0.815855606264524
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Rab4a ENSMUSG00000019478 0.893237063371557 0.946499553476016 0.550962091988128 0.946499553476016 0.946499553476016 0.946499553476016
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ap4m1 ENSMUSG00000019518 0.693012188876577 0.865241787067826 0.865241787067826 0.865241787067826 0.384630371524433 0.865241787067826
Reps1 ENSMUSG00000019854 0.675605194706463 0.675605194706463 0.307509707177996 0.675605194706463 0.479423697740017 0.675605194706463
Vta1 ENSMUSG00000019868 0.113723374771379 0.170585062157068 0.0473505327846662 0.142051598353999 0.788371093113175 0.788371093113175
Rab21 ENSMUSG00000020132 0.701795171667842 0.806688274368272 0.0933908615880712 0.280172584764213 0.806688274368272 0.806688274368272
Rab1 ENSMUSG00000020149 0.825052562287993 0.849717977248999 0.0501028421616306 0.150308526484892 0.849717977248999 0.849717977248999
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Sptbn1 ENSMUSG00000020315 0.25268494018726 0.75805482056178 0.849681638960586 0.849681638960586 0.519736247629835 0.779604371444752
Sar1b ENSMUSG00000020386 0.690020820648792 0.949637319019516 0.893251355666815 0.949637319019516 0.949637319019516 0.949637319019516
Arf5 ENSMUSG00000020440 0.165666248784099 0.248499373176148 0.0285673710213696 0.0857021130641088 0.852830478652352 0.852830478652352
Nbas ENSMUSG00000020576 0.831199458852206 0.831199458852206 0.0753846720564074 0.226154016169222 0.247920106909697 0.371880160364545
Trappc12 ENSMUSG00000020628 0.443387078271416 0.443387078271416 0.19006612444106 0.443387078271416 0.438716878108443 0.443387078271416
Cpd ENSMUSG00000020841 0.219666804573896 0.659000413721689 0.764022936291115 0.764022936291115 0.731291132373729 0.764022936291115
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Vamp2 ENSMUSG00000020894 0.713533370673868 0.871452400328244 0.871452400328244 0.871452400328244 0.58854331361707 0.871452400328244
Gosr2 ENSMUSG00000020946 0.74918210470492 0.74918210470492 0.707644228431412 0.74918210470492 0.687196877504888 0.74918210470492
Trappc6b ENSMUSG00000020993 0.527473180465239 0.862120781293246 0.728260818380006 0.862120781293246 0.862120781293246 0.862120781293246
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Tmed10 ENSMUSG00000021248 0.91201269072733 0.91201269072733 0.0678118927802477 0.203435678340743 0.553622790660843 0.830434185991265
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Trappc13 ENSMUSG00000021711 0.094972509193824 0.284917527581472 0.378120241073486 0.567180361610229 0.613294786270333 0.613294786270333
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
App ENSMUSG00000022892 0.669837081661211 0.704724196773938 0.332776383296367 0.704724196773938 0.704724196773938 0.704724196773938
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Bnip1 ENSMUSG00000024191 0.0346582671987526 0.0709621643207598 0.0473081095471732 0.0709621643207598 0.489381298258457 0.489381298258457
Vps52 ENSMUSG00000024319 0.621367928119512 0.788281082479196 0.357097229975649 0.788281082479196 0.788281082479196 0.788281082479196
Bin1 ENSMUSG00000024381 0.574927196052138 0.577653294094102 0.373888017702025 0.577653294094102 0.577653294094102 0.577653294094102
Ap3s1 ENSMUSG00000024480 0.514586521057514 0.771879781586271 0.4919120079912 0.771879781586271 0.862122885023046 0.862122885023046
Rab27b ENSMUSG00000024511 0.701756347702271 0.840430767538118 0.840430767538118 0.840430767538118 0.776218205300038 0.840430767538118
Dctn4 ENSMUSG00000024603 0.249672656716514 0.749017970149542 0.896379945733346 0.896379945733346 0.695948583617098 0.896379945733346
Vps51 ENSMUSG00000024797 0.105653507029143 0.310135981870419 0.206757321246946 0.310135981870419 0.38454930818886 0.38454930818886
Adrbk1 ENSMUSG00000024858 0.361229869200603 0.541844803800904 0.307695006136241 0.541844803800904 0.632826791918313 0.632826791918313
Rab1b ENSMUSG00000024870 0.652610640799931 0.837367992247653 0.105626814082895 0.316880442248684 0.837367992247653 0.837367992247653
Vti1a ENSMUSG00000024983 0.740217621733846 0.918271352477776 0.558935143922358 0.918271352477776 0.918271352477776 0.918271352477776
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Bet1l ENSMUSG00000025484 0.19008822545997 0.397015776682727 0.491886340128373 0.491886340128373 0.264677184455151 0.397015776682727
Copg2 ENSMUSG00000025607 0.87456316977634 0.87456316977634 0.812805153293911 0.87456316977634 0.519749364893375 0.87456316977634
Col7a1 ENSMUSG00000025650 0.635484736651941 0.803517910657567 0.494344634521326 0.803517910657567 0.803517910657567 0.803517910657567
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Agfg1 ENSMUSG00000026159 0.116488537274731 0.349465611824193 0.69301316538426 0.69301316538426 0.406625612113968 0.609938418170952
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Stx6 ENSMUSG00000026470 0.460093669640684 0.460093669640684 0.450531006864277 0.460093669640684 0.417949434571733 0.460093669640684
Copa ENSMUSG00000026553 0.582047574995334 0.582047574995334 0.203624746668274 0.465945120170432 0.310630080113621 0.465945120170432
Ppp6c ENSMUSG00000026753 0.0981074256256164 0.294322276876849 0.996850940601246 0.996850940601246 0.883891007319638 0.996850940601246
Golga1 ENSMUSG00000026754 0.211073540781294 0.316610311171941 0.158430081793005 0.316610311171941 0.43174020429507 0.43174020429507
Tor1b ENSMUSG00000026848 0.661171530407166 0.661171530407166 0.352849812994504 0.661171530407166 0.457643731257813 0.661171530407166
Gapvd1 ENSMUSG00000026867 0.69300453924434 0.69300453924434 0.340587538987273 0.69300453924434 0.489343980904243 0.69300453924434
Rab14 ENSMUSG00000026878 0.843529576141171 0.843529576141171 0.249526551449898 0.748579654349694 0.624319326999677 0.843529576141171
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Tbc1d20 ENSMUSG00000027465 0.246415881348434 0.369623822022651 0.110986060037067 0.332958180111202 0.684279771753536 0.684279771753536
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Stx16 ENSMUSG00000027522 0.859040552895603 0.859040552895603 0.704720456167024 0.859040552895603 0.41795005974617 0.859040552895603
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Rab33b ENSMUSG00000027739 0.524881324481564 0.524881324481564 0.52231570984546 0.524881324481564 0.438717185452543 0.524881324481564
Rab13 ENSMUSG00000027935 0.23363183120692 0.350447746810381 9.08157131734345e-05 0.000272447139520304 0.641312343458 0.641312343458
Ubap1 ENSMUSG00000028437 0.314201676680708 0.471302515021063 0.0127694601790513 0.038308380537154 0.74564890402646 0.74564890402646
Rgp1 ENSMUSG00000028468 0.604779490420249 0.815782189221284 0.749177827443046 0.815782189221284 0.815782189221284 0.815782189221284
Eps15 ENSMUSG00000028552 0.23839979523243 0.715199385697289 0.527457391543817 0.791186087315726 0.86523993911738 0.86523993911738
Pum1 ENSMUSG00000028580 0.977950194294777 0.977950194294777 0.501846360670251 0.977950194294777 0.824956148679795 0.977950194294777
Trappc3 ENSMUSG00000028847 0.463749372174641 0.977950416010785 0.701198392360333 0.977950416010785 0.977950416010785 0.977950416010785
Rint1 ENSMUSG00000028999 0.937073603772649 0.937073603772649 0.422451096973321 0.937073603772649 0.852843783462489 0.937073603772649
Stx18 ENSMUSG00000029125 0.309581512482546 0.737857261122885 0.927674707753686 0.927674707753686 0.49190484074859 0.737857261122885
Rab35 ENSMUSG00000029518 0.78528043292655 0.930789910218322 0.376027551158901 0.930789910218322 0.930789910218322 0.930789910218322
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Gcc1 ENSMUSG00000029708 0.464741208485198 0.698842272802265 0.698842272802265 0.698842272802265 0.613122438466004 0.698842272802265
Copg1 ENSMUSG00000030058 0.512041387981006 0.512041387981006 0.280304713996803 0.505139575519362 0.336759717012908 0.505139575519362
Tmf1 ENSMUSG00000030059 0.0268244330294316 0.080473299088295 0.469722256882648 0.704583385323973 0.946493484550472 0.946493484550472
Stx4a ENSMUSG00000030805 0.583114701383756 0.583114701383756 0.545715758505275 0.583114701383756 0.535245520817248 0.583114701383756
Dctn5 ENSMUSG00000030868 0.649764503294845 0.930791190486556 0.930791190486556 0.930791190486556 0.303949914271332 0.911849742813996
Arfip2 ENSMUSG00000030881 0.968488970040684 0.968488970040684 0.672464777544939 0.968488970040684 0.655477247667167 0.968488970040684
Cttn ENSMUSG00000031078 0.890132912119958 0.890132912119958 0.550893815794547 0.890132912119958 0.752121469870449 0.890132912119958
Dctn6 ENSMUSG00000031516 0.545696360893338 0.672690832060612 0.143686683170707 0.43106004951212 0.672690832060612 0.672690832060612
Ap1g1 ENSMUSG00000031731 0.17807043340121 0.534211300203631 0.60488766421616 0.60488766421616 0.542679833235013 0.60488766421616
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Cog8 ENSMUSG00000031916 0.294556392391232 0.450315794610682 0.300210529740455 0.450315794610682 0.681286884777654 0.681286884777654
Cog2 ENSMUSG00000031979 0.171902633352347 0.327575868022518 0.342742960153102 0.342742960153102 0.218383912015012 0.327575868022518
Trappc4 ENSMUSG00000032112 0.203848537664166 0.472142219757722 0.404268328442987 0.472142219757722 0.472142219757722 0.472142219757722
Rab27a ENSMUSG00000032202 0.64973874878729 0.707574413376481 0.707574413376481 0.707574413376481 0.477083157844736 0.707574413376481
Tmed3 ENSMUSG00000032353 0.395493119852633 0.593239679778949 0.0872210924697727 0.261663277409318 0.635559765579929 0.635559765579929
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Kif9 ENSMUSG00000032489 0.852651985562056 0.95277494340192 0.95277494340192 0.95277494340192 0.893051561758697 0.95277494340192
Trappc8 ENSMUSG00000033382 0.138229469212802 0.414688407638407 0.949638566305517 0.949638566305517 0.604694278613409 0.907041417920113
Golgb1 ENSMUSG00000034243 0.165673481700082 0.248510222550123 0.0696022613363292 0.208806784008988 0.987403360838584 0.987403360838584
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Tbc1d10a ENSMUSG00000034412 0.602137687009539 0.740181369489312 0.45756491055059 0.740181369489312 0.740181369489312 0.740181369489312
Ankrd27 ENSMUSG00000034867 0.569569563592984 0.627210181364254 0.348839987958392 0.627210181364254 0.627210181364254 0.627210181364254
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Epn1 ENSMUSG00000035203 0.486916318044524 0.489403403033323 0.162096873199981 0.486290619599942 0.489403403033323 0.489403403033323
Cog5 ENSMUSG00000035933 0.301889159460623 0.452833739190935 0.692930585056204 0.692930585056204 0.249618048746943 0.452833739190935
Rab3gap1 ENSMUSG00000036104 0.98425729216023 0.98425729216023 0.731288218449471 0.98425729216023 0.713545543536675 0.98425729216023
Sbf1 ENSMUSG00000036529 0.37600799047846 0.522280265606346 0.373901872665545 0.522280265606346 0.522280265606346 0.522280265606346
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Rab8b ENSMUSG00000036943 0.464853387099749 0.806784521861543 0.981107568585402 0.981107568585402 0.537856347907695 0.806784521861543
Bicd2 ENSMUSG00000037933 0.188558410070277 0.422937960694121 0.281958640462747 0.422937960694121 0.692946871935085 0.692946871935085
Trappc11 ENSMUSG00000038102 0.740092016826772 0.740092016826772 0.457621085091718 0.740092016826772 0.629928919607601 0.740092016826772
Sbf2 ENSMUSG00000038371 0.908873953217301 0.908873953217301 0.890136154521336 0.908873953217301 0.35705797334954 0.908873953217301
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Tbc1d17 ENSMUSG00000038520 0.10144889267115 0.304346678013449 0.313373449998798 0.470060174998197 0.79137614013413 0.79137614013413
Arfrp1 ENSMUSG00000038671 0.320994413286289 0.481491619929434 0.122042650948381 0.366127952845144 0.749059059663526 0.749059059663526
Tbc1d25 ENSMUSG00000039201 0.402038402236954 0.830350784447286 0.553567189631524 0.830350784447286 0.883879804882268 0.883879804882268
Tbc1d2 ENSMUSG00000039813 0.354999710776454 0.651064940968246 0.434043293978831 0.651064940968246 0.896375251853633 0.896375251853633
Hip1 ENSMUSG00000039959 0.911982660237219 0.911982660237219 0.641239476621553 0.911982660237219 0.893244435404828 0.911982660237219
Trappc5 ENSMUSG00000040236 0.68430546504773 0.68430546504773 0.296437723306429 0.68430546504773 0.638450010093336 0.68430546504773
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Adrbk2 ENSMUSG00000042249 0.905704972160358 0.933950881520103 0.550754227659045 0.933950881520103 0.933950881520103 0.933950881520103
Hps4 ENSMUSG00000042328 0.464810672479667 0.632782508531239 0.113690003833535 0.341070011500605 0.632782508531239 0.632782508531239
Tbc1d10b ENSMUSG00000042492 0.362986514683911 0.544479772025867 0.328794307304242 0.544479772025867 0.757959235020951 0.757959235020951
Pla2g6 ENSMUSG00000042632 0.133661603408023 0.203887141848746 0.203887141848746 0.203887141848746 0.17904146984763 0.203887141848746
Sys1 ENSMUSG00000045503 0.0152643007233324 0.0228964510849985 0.00330599018088915 0.00991797054266744 0.821986076879709 0.821986076879709
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Arf1 ENSMUSG00000048076 0.955934404320847 0.955934404320847 0.22292706614467 0.668781198434009 0.678471977629707 0.955934404320847
Vps37c ENSMUSG00000048832 0.899346352716889 0.899346352716889 0.307560750119503 0.899346352716889 0.701356730347006 0.899346352716889
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Arf3 ENSMUSG00000051853 0.61052430566124 0.91578645849186 0.517157075063747 0.91578645849186 0.930809237791053 0.930809237791053
Ppp6r1 ENSMUSG00000052296 0.445099582575574 0.667649373863362 0.283817621638636 0.667649373863362 0.849513726319043 0.849513726319043
Dennd4a ENSMUSG00000053641 0.506787812327301 0.768006652621308 0.98425081610098 0.98425081610098 0.512004435080872 0.768006652621308
Cope ENSMUSG00000055681 0.101761802385262 0.101761802385262 0.00705457727388242 0.0105818659108236 0.00421448970487089 0.0105818659108236
Apol8 ENSMUSG00000056656 0.784633163944802 0.803972950501445 0.625700232844416 0.803972950501445 0.803972950501445 0.803972950501445
Bloc1s3 ENSMUSG00000057667 0.550914796314054 0.826372194471081 0.427121710263959 0.826372194471081 0.949651224946529 0.949651224946529
Sptan1 ENSMUSG00000057738 0.794455294144298 0.794455294144298 0.779263044228689 0.794455294144298 0.55361219524715 0.794455294144298
Tmed9 ENSMUSG00000058569 0.289136217297457 0.393230370442055 0.285540817241893 0.393230370442055 0.393230370442055 0.393230370442055
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Kif13b ENSMUSG00000060012 0.825065979446263 0.825065979446263 0.758155212029761 0.825065979446263 0.649810810611423 0.825065979446263
Kif27 ENSMUSG00000060176 0.90794064172691 0.974602699673214 0.583115579423678 0.974602699673214 0.974602699673214 0.974602699673214
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Bloc1s4 ENSMUSG00000060708 0.899428444594652 0.899428444594652 0.0822220949456355 0.246666284836907 0.791309498080764 0.899428444594652
Arl1 ENSMUSG00000060904 0.977954922786188 0.977954922786188 0.883883578019259 0.977954922786188 0.369504346512649 0.977954922786188
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Cd59b ENSMUSG00000068686 0.126913257487361 0.190369886231042 0.0189044929134169 0.0567134787402508 0.38230972002902 0.38230972002902
Fcho1 ENSMUSG00000070000 0.375726943718728 0.943333432449234 0.689872232697787 0.943333432449234 0.943333432449234 0.943333432449234
Rabepk ENSMUSG00000070953 0.230468444889404 0.345702667334107 0.113689596861401 0.341068790584202 0.49433381603067 0.49433381603067
Fnbp1 ENSMUSG00000075415 0.79143887338941 0.79143887338941 0.737225699259388 0.79143887338941 0.618846781755802 0.79143887338941
Rab11b ENSMUSG00000077450 0.190060598965329 0.285090898447994 0.0597551130703255 0.179265339210976 0.64697717804138 0.64697717804138
Mon1b ENSMUSG00000078908 0.77626936738718 0.977961380140919 0.785360586740878 0.977961380140919 0.977961380140919 0.977961380140919
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612
Rab7 ENSMUSG00000079477 0.265113468659632 0.795340405978895 0.638454024580386 0.927499695249106 0.927499695249106 0.927499695249106
Galnt2 ENSMUSG00000089704 0.268985937363855 0.268985937363855 0.199130154782685 0.268985937363855 0.150476872515985 0.268985937363855
Gm20388 ENSMUSG00000092329 0.10278856234163 0.308365687024891 0.918103384510298 0.918103384510298 0.63252515883349 0.918103384510298

Switching of origins to a post-replicative state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

DNA Double-Strand Break Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Paxip1 ENSMUSG00000002221 0.843499529111168 0.940196430274366 0.701636481517852 0.940196430274366 0.940196430274366 0.940196430274366
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Ppp5c ENSMUSG00000003099 0.734155957610943 0.855937200255394 0.855937200255394 0.855937200255394 0.754985282103299 0.855937200255394
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Rad51c ENSMUSG00000007646 0.558862186064833 0.88698773329794 0.88698773329794 0.88698773329794 0.649708749511075 0.88698773329794
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Eya2 ENSMUSG00000017897 0.883900275850861 0.883900275850861 0.574973102444853 0.883900275850861 0.868343217484915 0.883900275850861
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Xrcc3 ENSMUSG00000021287 0.256280686890594 0.716466352440455 0.596743151103392 0.716466352440455 0.716466352440455 0.716466352440455
Polk ENSMUSG00000021668 0.0285502680118643 0.085650804035593 0.553581335711499 0.572299726498817 0.572299726498817 0.572299726498817
Rad1 ENSMUSG00000022248 0.758174236709342 0.770219294983185 0.770219294983185 0.770219294983185 0.684298792067107 0.770219294983185
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Mus81 ENSMUSG00000024906 0.317161644537185 0.317161644537185 0.309558578812616 0.317161644537185 0.309567687476581 0.317161644537185
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Poll ENSMUSG00000025218 0.0265647205428424 0.0398470808142636 0.0126226286012384 0.0378678858037152 0.411124104047638 0.411124104047638
Atrip ENSMUSG00000025646 0.28027861469881 0.461483553086212 0.307655702057475 0.461483553086212 0.7253564258483 0.7253564258483
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Dclre1c ENSMUSG00000026648 0.791349536535927 0.791349536535927 0.183165715330873 0.549497145992619 0.545547743610266 0.791349536535927
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Eya3 ENSMUSG00000028886 0.354939940500405 0.499334371435975 0.438729069044625 0.499334371435975 0.499334371435975 0.499334371435975
Xrcc2 ENSMUSG00000028933 0.630043038404972 0.630043038404972 0.580403913049553 0.630043038404972 0.545715713606246 0.630043038404972
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Rad52 ENSMUSG00000030166 0.70176361248832 0.85592930830365 0.85592930830365 0.85592930830365 0.704722813708938 0.85592930830365
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Sirt6 ENSMUSG00000034748 0.198275859846668 0.594827579540004 0.83121063778572 0.83121063778572 0.74016838660268 0.83121063778572
Rif1 ENSMUSG00000036202 0.289206890832308 0.433810336248461 0.249649284946705 0.433810336248461 0.719440962207448 0.719440962207448
Rad9b ENSMUSG00000038569 0.558891109810946 0.838336664716419 0.868330761133957 0.868330761133957 0.321041642259884 0.838336664716419
Slx4 ENSMUSG00000039738 0.472155600959342 0.865220680142318 0.728303881107593 0.865220680142318 0.865220680142318 0.865220680142318
Lig4 ENSMUSG00000049717 0.0926013994713989 0.277804198414197 0.94961238758366 0.94961238758366 0.812692402337864 0.94961238758366
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Xrcc1 ENSMUSG00000051768 0.373889676064885 0.560834514097327 0.311472140296653 0.560834514097327 0.782330754853731 0.782330754853731
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Slx1b ENSMUSG00000059772 0.273102203263939 0.819306609791816 0.809671281226618 0.955923206999278 0.955923206999278 0.955923206999278
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Eme2 ENSMUSG00000073436 0.484457700482441 0.794981788107556 0.84354063447501 0.84354063447501 0.52998785873837 0.794981788107556
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

Synthesis of active ubiquitin: roles of E1 and E2 enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Uba1 ENSMUSG00000001924 0.908803691422935 0.908803691422935 0.180720568583336 0.542161705750009 0.905682369178817 0.908803691422935
Ube2z ENSMUSG00000014349 0.285616340060384 0.428424510090576 0.0455636788438355 0.136691036531506 0.880762632718241 0.880762632718241
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Ube2w ENSMUSG00000025939 0.791401185592327 0.871447334705611 0.627211990288362 0.871447334705611 0.871447334705611 0.871447334705611
Ube2e3 ENSMUSG00000027011 0.340776953299827 0.51116542994974 0.171918053165233 0.51116542994974 0.949652044564859 0.949652044564859
Ube2k ENSMUSG00000029203 0.0858295329128809 0.257488598738643 0.491827144094887 0.737740716142331 0.896360038379953 0.896360038379953
Uba6 ENSMUSG00000035898 0.0236769861350615 0.0710309584051846 0.348728857286561 0.523093285929841 0.902625073237022 0.902625073237022
Ube2r2 ENSMUSG00000036241 0.0381775741237514 0.0572663611856271 0.000342499215846288 0.00102749764753886 0.646928752133708 0.646928752133708
Usp5 ENSMUSG00000038429 0.238370504774076 0.357555757161115 0.11930102964409 0.357555757161115 0.704671123451522 0.704671123451522
Ube2h ENSMUSG00000039159 0.212540512380975 0.318810768571462 0.0139776269096938 0.0419328807290814 0.785358692721386 0.785358692721386
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnpo1 ENSMUSG00000009470 0.494417786200833 0.788383945704149 0.788383945704149 0.788383945704149 0.687209982750423 0.788383945704149
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388

Positive epigenetic regulation of rRNA expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Mybbp1a ENSMUSG00000040463 0.155944840891198 0.32543444708292 0.21695629805528 0.32543444708292 0.824940780129597 0.824940780129597
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

B-WICH complex positively regulates rRNA expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Kat2a ENSMUSG00000020918 0.655260456178564 0.982890684267847 0.320829445696971 0.962488337090913 0.993695776134907 0.993695776134907
Polr1b ENSMUSG00000027395 0.35496753705184 0.809702899529212 0.809702899529212 0.809702899529212 0.740130238121082 0.809702899529212
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Taf1c ENSMUSG00000031832 0.415603332065243 0.623404998097865 0.356998725328697 0.623404998097865 0.707580181245161 0.707580181245161
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Mybbp1a ENSMUSG00000040463 0.155944840891198 0.32543444708292 0.21695629805528 0.32543444708292 0.824940780129597 0.824940780129597
Cd3eap ENSMUSG00000047649 0.607715266664269 0.911572899996403 0.556257565568093 0.911572899996403 0.974812262452375 0.974812262452375
Polr1a ENSMUSG00000049553 0.828133512087228 0.828133512087228 0.136240624538793 0.40872187361638 0.672706781327347 0.828133512087228
Ercc6 ENSMUSG00000054051 0.507002983330739 0.731278870171806 0.494422034310553 0.731278870171806 0.731278870171806 0.731278870171806
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Taf1b ENSMUSG00000059669 0.635659254056859 0.890130912902361 0.448091665577991 0.890130912902361 0.890130912902361 0.890130912902361
Taf1a ENSMUSG00000072258 0.434068649219224 0.651102973828835 0.303934307034702 0.651102973828835 0.846655244836153 0.846655244836153

Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dcp1a ENSMUSG00000021962 0.690023514301148 0.791367053234031 0.791367053234031 0.791367053234031 0.369647006248234 0.791367053234031
Dcp2 ENSMUSG00000024472 0.761141743188737 0.893240145114636 0.635649739313214 0.893240145114636 0.893240145114636 0.893240145114636
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388

UCH proteinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Uchl5 ENSMUSG00000018189 0.219896114839815 0.525896260581595 0.350597507054397 0.525896260581595 0.76099969924541 0.76099969924541
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Bap1 ENSMUSG00000021901 0.413407788783879 0.620111683175819 0.108343937037946 0.325031811113838 0.797530303516965 0.797530303516965
Uchl3 ENSMUSG00000022111 0.0464454591483031 0.139336377444909 0.93708633076452 0.93708633076452 0.472044357804358 0.708066536706537
Mbd6 ENSMUSG00000025409 0.678201875842515 0.962204370529384 0.162065246181141 0.486195738543423 0.962204370529384 0.962204370529384
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Adrm1 ENSMUSG00000039041 0.104965021816539 0.157447532724809 0.0397463098480413 0.119238929544124 0.571749204282725 0.571749204282725
Foxk2 ENSMUSG00000039275 0.49692369178867 0.815866894959488 0.815866894959488 0.815866894959488 0.800575809275715 0.815866894959488
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995
Asxl1 ENSMUSG00000042548 0.408861338264557 0.930794506513674 0.710447901186555 0.930794506513674 0.930794506513674 0.930794506513674
Foxk1 ENSMUSG00000056493 0.90262961659103 0.971667329399804 0.971667329399804 0.971667329399804 0.912012543977666 0.971667329399804
Hist2h2aa1 ENSMUSG00000063954 0.0180627120506501 0.0270940680759751 0.00164950179473926 0.00494850538421779 0.451850862955937 0.451850862955937
Hist1h2ac ENSMUSG00000069270 0.930785089293876 0.987397197992179 0.678483304741697 0.987397197992179 0.987397197992179 0.987397197992179
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883
Hist3h2a ENSMUSG00000078851 0.752152564586074 0.752152564586074 0.731272204600638 0.752152564586074 0.74020990261945 0.752152564586074

Intracellular signaling by second messengers

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Kit ENSMUSG00000005672 0.843522864090151 0.843522864090151 0.764189096979214 0.843522864090151 0.785324030328461 0.843522864090151
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Pten ENSMUSG00000013663 0.235262802048582 0.705788406145746 0.499430052531673 0.74914507879751 0.949651275472104 0.949651275472104
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Mdm2 ENSMUSG00000020184 0.190099574082196 0.570298722246587 0.846656834328273 0.930811588066432 0.930811588066432 0.930811588066432
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mta1 ENSMUSG00000021144 0.96850938091585 0.96850938091585 0.955937535289744 0.96850938091585 0.716417092179727 0.96850938091585
Pde1b ENSMUSG00000022489 0.553456325011793 0.710292047982395 0.710292047982395 0.710292047982395 0.299870866599513 0.710292047982395
Maf1 ENSMUSG00000022553 0.232078311401733 0.3481174671026 0.00785414401890984 0.0235624320567295 0.899487598488328 0.899487598488328
Strn ENSMUSG00000024077 0.393265129458563 0.987400303068685 0.981106423222112 0.987400303068685 0.987400303068685 0.987400303068685
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Ring1 ENSMUSG00000024325 0.431678049361225 0.604989697809639 0.202498799078166 0.604989697809639 0.604989697809639 0.604989697809639
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Tnks2 ENSMUSG00000024811 0.266317347575066 0.798952042725197 0.987404403039068 0.987404403039068 0.652551064031966 0.978826596047949
Rps6kb2 ENSMUSG00000024830 0.558832641080203 0.918264695430269 0.794434821824476 0.918264695430269 0.918264695430269 0.918264695430269
Adrbk1 ENSMUSG00000024858 0.361229869200603 0.541844803800904 0.307695006136241 0.541844803800904 0.632826791918313 0.632826791918313
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Cbx8 ENSMUSG00000025578 0.94336669163571 0.94650749307076 0.566930488850384 0.94650749307076 0.94650749307076 0.94650749307076
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Rnf2 ENSMUSG00000026484 0.399973507167973 0.599960260751959 0.128079502824866 0.384238508474597 0.828132888531452 0.828132888531452
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Bmi1 ENSMUSG00000026739 0.00729819529521933 0.021894585885658 0.161967705990309 0.242951558985463 0.591224696991283 0.591224696991283
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Pip5k1a ENSMUSG00000028126 0.831214908220546 0.971665220311805 0.61048002282776 0.971665220311805 0.971665220311805 0.971665220311805
Rragc ENSMUSG00000028646 0.431575702734737 0.647363554102105 0.0665706810652524 0.199712043195757 0.785314157129054 0.785314157129054
Phc2 ENSMUSG00000028796 0.658244563909369 0.803546285016641 0.474597894937187 0.803546285016641 0.803546285016641 0.803546285016641
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Pdgfra ENSMUSG00000029231 0.840454858184603 0.937079579057874 0.937079579057874 0.937079579057874 0.230518951155773 0.691556853467318
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Mkrn1 ENSMUSG00000029922 0.216490221537255 0.324735332305882 0.118244827676101 0.324735332305882 0.61016482119888 0.61016482119888
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Phlpp2 ENSMUSG00000031732 0.840472980521873 0.840472980521873 0.479525407473586 0.719288111210379 0.420200818877701 0.719288111210379
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Wwp2 ENSMUSG00000031930 0.321026297928993 0.321026297928993 0.109221743718641 0.321026297928993 0.302058762011907 0.321026297928993
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Phc3 ENSMUSG00000037652 0.479503094379685 0.785358692721386 0.785358692721386 0.785358692721386 0.604954309795222 0.785358692721386
Rnf146 ENSMUSG00000038876 0.693030220217436 0.977953218909713 0.977953218909713 0.977953218909713 0.779236353832042 0.977953218909713
Irs2 ENSMUSG00000038894 0.032873592672881 0.098620778018643 0.81581974735777 0.81581974735777 0.574864724198363 0.81581974735777
Stub1 ENSMUSG00000039615 0.273175121956661 0.409762682934992 0.019103793887471 0.057311381662413 0.69009096413351 0.69009096413351
Cbx4 ENSMUSG00000039989 0.840466477580683 0.840466477580683 0.632860117454638 0.840466477580683 0.764176062411686 0.840466477580683
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823
Slc38a9 ENSMUSG00000047789 0.422482462453883 0.704714577783488 0.51713064647971 0.704714577783488 0.704714577783488 0.704714577783488
Foxo3 ENSMUSG00000048756 0.433976161039521 0.650964241559282 0.386787523227173 0.650964241559282 0.890122463783881 0.890122463783881
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Mta3 ENSMUSG00000055817 0.955936783328286 0.955936783328286 0.681379004603109 0.955936783328286 0.624386316844351 0.955936783328286
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

VEGFA-VEGFR2 Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Rasa1 ENSMUSG00000021549 0.222896992458366 0.376945323539439 0.251296882359626 0.376945323539439 0.825080354293345 0.825080354293345
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Ptk2b ENSMUSG00000059456 0.865237524745001 0.927658298243105 0.927658298243105 0.927658298243105 0.806650982526346 0.927658298243105
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Nck2 ENSMUSG00000066877 0.695886060438501 0.773225423434546 0.393349353627609 0.773225423434546 0.773225423434546 0.773225423434546

DNA Damage Recognition in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddb2 ENSMUSG00000002109 0.361104971365262 0.60649106688285 0.716489200491167 0.716489200491167 0.4043273779219 0.60649106688285
Rad23a ENSMUSG00000003813 0.41906194166477 0.628592912497155 0.108288729865328 0.324866189595984 0.902371065179773 0.902371065179773
Tfpt ENSMUSG00000006335 0.342538381028472 0.767153072849353 0.767153072849353 0.767153072849353 0.535152807793001 0.767153072849353
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ddb1 ENSMUSG00000024740 0.118806900841668 0.134845419814105 0.000434762089206544 0.00130428626761963 0.134845419814105 0.134845419814105
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Rad23b ENSMUSG00000028426 0.0529667250889011 0.158900175266703 0.666975629018124 0.890106267240024 0.890106267240024 0.890106267240024
Ruvbl1 ENSMUSG00000030079 0.831199607424023 0.831199607424023 0.340782144990542 0.554351589928199 0.369567726618799 0.554351589928199
Ino80e ENSMUSG00000030689 0.859025599963515 0.984255763103148 0.47219350891448 0.984255763103148 0.984255763103148 0.984255763103148
Cul4b ENSMUSG00000031095 0.348837558568862 0.846307478345798 0.564204985563865 0.846307478345798 0.908865613881939 0.908865613881939
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Cul4a ENSMUSG00000031446 0.974558692386735 0.974558692386735 0.0633665590041636 0.190099677012491 0.681650728291411 0.974558692386735
Ino80 ENSMUSG00000034154 0.767131998900763 0.968509025763117 0.397770787398907 0.968509025763117 0.968509025763117 0.968509025763117
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Ino80d ENSMUSG00000040865 0.188667374126092 0.566002122378275 0.477080940298254 0.715621410447382 0.755083276179888 0.755083276179888
Nfrkb ENSMUSG00000042185 0.719394492315569 0.965374589314995 0.965374589314995 0.965374589314995 0.644089978688174 0.965374589314995

ERK/MAPK targets

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

Phosphorylation of the APC/C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617

Regulation of PLK1 Activity at G2/M Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293

MAPK targets/ Nuclear events mediated by MAP kinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

DNA Double Strand Break Response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Baz1b ENSMUSG00000002748 0.556282900656864 0.776257036227345 0.460065663767987 0.776257036227345 0.776257036227345 0.776257036227345
Ppp5c ENSMUSG00000003099 0.734155957610943 0.855937200255394 0.855937200255394 0.855937200255394 0.754985282103299 0.855937200255394
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Eya2 ENSMUSG00000017897 0.883900275850861 0.883900275850861 0.574973102444853 0.883900275850861 0.868343217484915 0.883900275850861
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Kdm4b ENSMUSG00000024201 0.283866909032166 0.425800363548249 0.266370389855722 0.425800363548249 0.874562766976567 0.874562766976567
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Eya3 ENSMUSG00000028886 0.354939940500405 0.499334371435975 0.438729069044625 0.499334371435975 0.499334371435975 0.499334371435975
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Brcc3 ENSMUSG00000031201 0.00241261566119895 0.00723784698359684 0.0306335339912109 0.0459503009868163 0.632575285752079 0.632575285752079
Smarca5 ENSMUSG00000031715 0.380321195287249 0.99685115929208 0.99685115929208 0.99685115929208 0.865242010605065 0.99685115929208
Babam1 ENSMUSG00000031820 0.399683298233703 0.599524947350555 0.0102236459693449 0.0306709379080348 0.990548243428438 0.990548243428438
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Bre ENSMUSG00000052139 0.937007875661495 0.937007875661495 0.0689911181382434 0.20697335441473 0.182792760158689 0.274189140238034
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

Nuclear Envelope (NE) Reassembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Emd ENSMUSG00000001964 0.0473125721546617 0.141937716463985 0.38463984374418 0.576959765616271 0.794423842370773 0.794423842370773
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Cc2d1b ENSMUSG00000028582 0.212523363262511 0.637570089787534 0.583031954118229 0.652609153567208 0.652609153567208 0.652609153567208
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Ankle2 ENSMUSG00000029501 0.740214041940217 0.797514178020519 0.797514178020519 0.797514178020519 0.725346358813915 0.797514178020519
Ist1 ENSMUSG00000031729 0.952795870425307 0.952795870425307 0.82200572007944 0.952795870425307 0.669852038936102 0.952795870425307
Vps4a ENSMUSG00000031913 0.514565781407363 0.771848672111044 0.0836563479175605 0.250969043752682 0.837372989287261 0.837372989287261
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Chmp4b ENSMUSG00000038467 0.558864867683465 0.803612064505726 0.406646884364638 0.803612064505726 0.803612064505726 0.803612064505726
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Lemd2 ENSMUSG00000044857 0.0271415064206202 0.0814245192618606 0.0614176382580693 0.092126457387104 0.940218606986825 0.940218606986825
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091

Interleukin-17 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Tab3 ENSMUSG00000035476 0.334634039301788 0.843502394766919 0.843502394766919 0.843502394766919 0.574862799578782 0.843502394766919
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ube2v1 ENSMUSG00000078923 0.707651456421661 0.707651456421661 0.0690119256001669 0.207035776800501 0.649779661098828 0.707651456421661

MAP kinase activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Tab3 ENSMUSG00000035476 0.334634039301788 0.843502394766919 0.843502394766919 0.843502394766919 0.574862799578782 0.843502394766919
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ube2v1 ENSMUSG00000078923 0.707651456421661 0.707651456421661 0.0690119256001669 0.207035776800501 0.649779661098828 0.707651456421661

E3 ubiquitin ligases ubiquitinate target proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hltf ENSMUSG00000002428 0.469559400197792 0.783035674339656 0.522023782893104 0.783035674339656 0.984253887202867 0.984253887202867
Paf1 ENSMUSG00000003437 0.204634036079109 0.613902108237327 0.527458314915781 0.791187472373672 0.874327425726679 0.874327425726679
Ctr9 ENSMUSG00000005609 0.33831505760737 0.953423628021444 0.635615752014296 0.953423628021444 0.974789216331036 0.974789216331036
Ube2a ENSMUSG00000016308 0.615976075161646 0.880765963819546 0.00447455506548073 0.0134236651964422 0.880765963819546 0.880765963819546
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Rnf144a ENSMUSG00000020642 0.785340357892338 0.785340357892338 0.448119551026687 0.704626611701217 0.469751074467478 0.704626611701217
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Wac ENSMUSG00000024283 0.0434174539866481 0.130252361959944 0.429356293987237 0.452649977383344 0.452649977383344 0.452649977383344
Cdc73 ENSMUSG00000026361 0.429428431750883 0.752144798698776 0.752144798698776 0.752144798698776 0.517125069686365 0.752144798698776
Rtf1 ENSMUSG00000027304 0.535198417979679 0.802797626969519 0.438701663956386 0.802797626969519 0.937073863298095 0.937073863298095
Rnf20 ENSMUSG00000028309 0.76415898641512 0.924530595215217 0.924530595215217 0.924530595215217 0.865241638042382 0.924530595215217
Pex14 ENSMUSG00000028975 0.194171505737175 0.291257258605763 0.080828462166762 0.242485386500286 0.971666162661201 0.971666162661201
Rad18 ENSMUSG00000030254 0.274811771450367 0.577392108098863 0.450487835959263 0.577392108098863 0.577392108098863 0.577392108098863
Rnf40 ENSMUSG00000030816 0.322848210432661 0.603267145078526 0.402178096719017 0.603267145078526 0.930785590716957 0.930785590716957
Leo1 ENSMUSG00000042487 0.77001588028276 0.949606613327679 0.041719278176392 0.125157834529176 0.949606613327679 0.949606613327679
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Rraga ENSMUSG00000070934 0.81584811297909 0.81584811297909 0.00942254589688961 0.0282676376906688 0.348680078701238 0.523020118051857
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Shprh ENSMUSG00000090112 0.561578278019075 0.561578278019075 0.378124993618767 0.561578278019075 0.330806941366433 0.561578278019075
Ube2d2a ENSMUSG00000091896 0.758096670567164 0.764104563898279 0.121190362897058 0.363571088691173 0.764104563898279 0.764104563898279

Signalling to ERKs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Map2k1 ENSMUSG00000004936 0.681394613648861 0.701784261887543 0.282089446675367 0.701784261887543 0.701784261887543 0.701784261887543
Crkl ENSMUSG00000006134 0.346843138246333 0.520264707369499 0.269827914159667 0.520264707369499 0.632858863635973 0.632858863635973
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Ralgds ENSMUSG00000026821 0.812804004429882 0.812804004429882 0.583105102689558 0.812804004429882 0.543088585547914 0.812804004429882
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Map2k2 ENSMUSG00000035027 0.00128627312451186 0.00224960999548579 0.00149973999699052 0.00224960999548579 0.516519953015554 0.516519953015554
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

RNA Polymerase III Transcription Initiation From Type 2 Promoter

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr3d ENSMUSG00000000776 0.761126502106042 0.846616219142862 0.561550189092716 0.846616219142862 0.846616219142862 0.846616219142862
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Tbp ENSMUSG00000014767 0.155054546179762 0.232581819269643 0.0642453413107943 0.192736023932383 0.927667322036519 0.927667322036519
Polr3a ENSMUSG00000025280 0.971646863707662 0.971646863707662 0.535241550487159 0.802862325730738 0.443129429388144 0.802862325730738
Crcp ENSMUSG00000025532 0.722390483474848 0.981108062103152 0.330788738420202 0.981108062103152 0.981108062103152 0.981108062103152
Gtf3c5 ENSMUSG00000026816 0.240001081265092 0.360001621897639 0.209608182047211 0.360001621897639 0.8036268665289 0.8036268665289
Polr3f ENSMUSG00000027427 0.481991346848557 0.481991346848557 0.399969920324772 0.481991346848557 0.429415421049493 0.481991346848557
Gtf3c1 ENSMUSG00000032777 0.514477384975409 0.771716077463113 0.326830323471223 0.771716077463113 0.990549428512413 0.990549428512413
Gtf3c4 ENSMUSG00000035666 0.984256165622295 0.984256165622295 0.162099658146484 0.486298974439453 0.921405886685337 0.984256165622295
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Polr3k ENSMUSG00000038628 0.556103431783981 0.962213191153128 0.962213191153128 0.962213191153128 0.902619068543644 0.962213191153128
Gtf3c3 ENSMUSG00000041303 0.482006439491822 0.704726334199839 0.212555196216459 0.637665588649376 0.704726334199839 0.704726334199839
Bdp1 ENSMUSG00000049658 0.0597538715244959 0.179261614573488 0.302064613928294 0.45309692089244 0.698850688450806 0.698850688450806

Clathrin-mediated endocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.296334205815322 0.877674294270367 0.877674294270367 0.877674294270367 0.834246397436796 0.877674294270367
Hip1r ENSMUSG00000000915 0.545683876865408 0.996850730657377 0.974810147975717 0.996850730657377 0.996850730657377 0.996850730657377
Ap2a2 ENSMUSG00000002957 0.722369613721913 0.849731012785351 0.079435535154886 0.238306605464658 0.849731012785351 0.849731012785351
Sh3gl1 ENSMUSG00000003200 0.734257170446249 0.734257170446249 0.404418970770285 0.606628456155427 0.397733389607841 0.606628456155427
Ubqln1 ENSMUSG00000005312 0.886984660793428 0.886984660793428 0.201083689829996 0.603251069489988 0.764118582319767 0.886984660793428
Eps15l1 ENSMUSG00000006276 0.785251119050755 0.785251119050755 0.666888813786863 0.785251119050755 0.731161645452711 0.785251119050755
Ap2s1 ENSMUSG00000008036 0.103939800237398 0.155909700356097 0.0146441136382767 0.04393234091483 0.556177824578101 0.556177824578101
Nedd8 ENSMUSG00000010376 0.0930873076752985 0.279261923025895 0.344738400595376 0.42674302697895 0.42674302697895 0.42674302697895
Hspa8 ENSMUSG00000015656 0.00104367787906989 0.00313103363720967 0.251252051962816 0.376878077944224 0.843556432955716 0.843556432955716
Pacsin2 ENSMUSG00000016664 0.770104729886689 0.849665402660967 0.0513047073248464 0.153914121974539 0.849665402660967 0.849665402660967
Rab5a ENSMUSG00000017831 0.788392528177461 0.946508047696209 0.479524375432608 0.946508047696209 0.946508047696209 0.946508047696209
Arrb1 ENSMUSG00000018909 0.924531233831644 0.924531233831644 0.216940919613781 0.650822758841343 0.460080671032609 0.690121006548914
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Reps1 ENSMUSG00000019854 0.675605194706463 0.675605194706463 0.307509707177996 0.675605194706463 0.479423697740017 0.675605194706463
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Vamp2 ENSMUSG00000020894 0.713533370673868 0.871452400328244 0.871452400328244 0.871452400328244 0.58854331361707 0.871452400328244
Ap2m1 ENSMUSG00000022841 0.785356518044595 0.918270224895635 0.918270224895635 0.918270224895635 0.632834012586015 0.918270224895635
Bin1 ENSMUSG00000024381 0.574927196052138 0.577653294094102 0.373888017702025 0.577653294094102 0.577653294094102 0.577653294094102
Adrbk1 ENSMUSG00000024858 0.361229869200603 0.541844803800904 0.307695006136241 0.541844803800904 0.632826791918313 0.632826791918313
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Agfg1 ENSMUSG00000026159 0.116488537274731 0.349465611824193 0.69301316538426 0.69301316538426 0.406625612113968 0.609938418170952
Cops7b ENSMUSG00000026240 0.373873145363491 0.499391047686086 0.15620806809202 0.46862420427606 0.499391047686086 0.499391047686086
Tor1b ENSMUSG00000026848 0.661171530407166 0.661171530407166 0.352849812994504 0.661171530407166 0.457643731257813 0.661171530407166
Gapvd1 ENSMUSG00000026867 0.69300453924434 0.69300453924434 0.340587538987273 0.69300453924434 0.489343980904243 0.69300453924434
Cops2 ENSMUSG00000027206 0.00178243614491652 0.00534730843474957 0.135091346072809 0.202637019109213 0.785330884616183 0.785330884616183
Arfgap1 ENSMUSG00000027575 0.259618343777794 0.540452334646328 0.436366833698772 0.540452334646328 0.540452334646328 0.540452334646328
Eps15 ENSMUSG00000028552 0.23839979523243 0.715199385697289 0.527457391543817 0.791186087315726 0.86523993911738 0.86523993911738
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Cttn ENSMUSG00000031078 0.890132912119958 0.890132912119958 0.550893815794547 0.890132912119958 0.752121469870449 0.890132912119958
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Pip5k1c ENSMUSG00000034902 0.9685207183876 0.9685207183876 0.965374079367124 0.9685207183876 0.825073474795282 0.9685207183876
Ap2b1 ENSMUSG00000035152 0.968520735950124 0.968520735950124 0.294703260846548 0.884109782539643 0.666978111454497 0.968520735950124
Epn1 ENSMUSG00000035203 0.486916318044524 0.489403403033323 0.162096873199981 0.486290619599942 0.489403403033323 0.489403403033323
Hip1 ENSMUSG00000039959 0.911982660237219 0.911982660237219 0.641239476621553 0.911982660237219 0.893244435404828 0.911982660237219
Adrbk2 ENSMUSG00000042249 0.905704972160358 0.933950881520103 0.550754227659045 0.933950881520103 0.933950881520103 0.933950881520103
Cltc ENSMUSG00000047126 0.182146104404683 0.546438313214049 0.395538613847983 0.593307920771975 0.940228367318317 0.940228367318317
Fzd4 ENSMUSG00000049791 0.260841334336866 0.782524003010598 0.556159715742608 0.803454901033328 0.803454901033328 0.803454901033328
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Arrb2 ENSMUSG00000060216 0.887001800913669 0.887001800913669 0.672684630853216 0.887001800913669 0.527455544783781 0.887001800913669
Ap2a1 ENSMUSG00000060279 0.558924290423982 0.838386435635973 0.282071966469691 0.838386435635973 0.937086709300539 0.937086709300539
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Fcho1 ENSMUSG00000070000 0.375726943718728 0.943333432449234 0.689872232697787 0.943333432449234 0.943333432449234 0.943333432449234
Fnbp1 ENSMUSG00000075415 0.79143887338941 0.79143887338941 0.737225699259388 0.79143887338941 0.618846781755802 0.79143887338941
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

Beta-catenin phosphorylation cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Csnk1a1 ENSMUSG00000024576 0.346327182522591 0.91188749144334 0.806631502613227 0.91188749144334 0.91188749144334 0.91188749144334
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Amer1 ENSMUSG00000050332 0.317133822680462 0.630021125667124 0.630021125667124 0.630021125667124 0.452818916389513 0.630021125667124
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Frat1 ENSMUSG00000067199 0.170247366619243 0.255371049928864 0.125509925421442 0.255371049928864 0.285775076922933 0.285775076922933

SUMO is transferred from E1 to E2 (UBE2I, UBC9)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2i ENSMUSG00000015120 0.96535995800045 0.96535995800045 0.719432708582282 0.96535995800045 0.474499809996755 0.96535995800045
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Sae1 ENSMUSG00000052833 0.164331392096294 0.246497088144441 0.0139617122440403 0.041885136732121 0.51175049536174 0.51175049536174
Uba2 ENSMUSG00000052997 0.899498684506435 0.899498684506435 0.443341108050067 0.899498684506435 0.734201234777432 0.899498684506435

WNT mediated activation of DVL

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Csnk2b ENSMUSG00000024387 0.160827199220313 0.24124079883047 0.00999823491260399 0.029994704737812 0.677688669536065 0.677688669536065
Pip5k1b ENSMUSG00000024867 0.644126668339939 0.644126668339939 0.315196121553042 0.644126668339939 0.604949022972544 0.644126668339939
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Csnk2a2 ENSMUSG00000046707 0.44334161832477 0.665012427487156 0.303908021802352 0.665012427487156 0.902618148807823 0.902618148807823

HuR (ELAVL1) binds and stabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Anp32a ENSMUSG00000032249 0.740192056526801 0.818916972373276 0.818916972373276 0.818916972373276 0.73124464254036 0.818916972373276
Elavl1 ENSMUSG00000040028 0.39523615604547 0.592854234068205 0.244602064210725 0.592854234068205 0.733965993396344 0.733965993396344
Set ENSMUSG00000054766 0.896355468426295 0.896355468426295 0.791426176521882 0.896355468426295 0.843539944475959 0.896355468426295

Organelle biogenesis and maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb5 ENSMUSG00000001525 0.413376945511347 0.413376945511347 0.0721246804793198 0.216374041437959 0.344801900496077 0.413376945511347
Ift46 ENSMUSG00000002031 0.834159514292017 0.962209119240289 0.365060723987078 0.962209119240289 0.962209119240289 0.962209119240289
Prkar2b ENSMUSG00000002997 0.868251496781882 0.949602987926656 0.591118328548643 0.949602987926656 0.949602987926656 0.949602987926656
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Tnpo1 ENSMUSG00000009470 0.494417786200833 0.788383945704149 0.788383945704149 0.788383945704149 0.687209982750423 0.788383945704149
Tctex1d2 ENSMUSG00000014075 0.797530635276862 0.797530635276862 0.770221240361777 0.797530635276862 0.797527494551165 0.797530635276862
Cluap1 ENSMUSG00000014232 0.369624870888318 0.921394225079788 0.773212463474045 0.921394225079788 0.921394225079788 0.921394225079788
Atp5e ENSMUSG00000016252 7.07189257727825e-05 0.000107497936401154 7.16652909341026e-05 0.000107497936401154 0.547875489938384 0.547875489938384
Ift27 ENSMUSG00000016637 0.132011564794024 0.289019973601801 0.192679982401201 0.289019973601801 0.462485180772615 0.462485180772615
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ccdc41 ENSMUSG00000020024 0.0767204865353 0.2301614596059 0.359058162416547 0.538587243624821 0.737191999201571 0.737191999201571
Trip11 ENSMUSG00000021188 0.053505776128087 0.160517328384261 0.561547169869887 0.737184137760669 0.737184137760669 0.737184137760669
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Exoc2 ENSMUSG00000021357 0.874544623073993 0.921406376481653 0.921406376481653 0.921406376481653 0.707632544124845 0.921406376481653
Cct5 ENSMUSG00000022234 0.862131161807723 0.862131161807723 0.417960895790413 0.862131161807723 0.652608573178535 0.862131161807723
Asap1 ENSMUSG00000022377 0.770211163763636 0.952793301476563 0.566942451615172 0.952793301476563 0.952793301476563 0.952793301476563
Cep97 ENSMUSG00000022604 0.373879244215948 0.949641223502237 0.949641223502237 0.949641223502237 0.74314391198049 0.949641223502237
Arl13b ENSMUSG00000022911 0.429415059628686 0.968520223112328 0.71353490001315 0.968520223112328 0.968520223112328 0.968520223112328
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Cep89 ENSMUSG00000023072 0.233559506921179 0.658347900312982 0.658347900312982 0.658347900312982 0.574934719901611 0.658347900312982
Sfi1 ENSMUSG00000023764 0.831217340366823 0.831217340366823 0.794480606714156 0.831217340366823 0.588478039499412 0.831217340366823
Ift140 ENSMUSG00000024169 0.504257476172361 0.504257476172361 0.315280616140767 0.504257476172361 0.395296852347624 0.504257476172361
Tmem216 ENSMUSG00000024667 0.417854541537638 0.474624532646932 0.474624532646932 0.474624532646932 0.459977954546563 0.474624532646932
Csnk1d ENSMUSG00000025162 0.124068988052659 0.186103482078989 0.0683883599248029 0.186103482078989 0.704590609991677 0.704590609991677
Gbf1 ENSMUSG00000025224 0.354586167078464 0.531879250617697 0.273268622425343 0.531879250617697 0.981086257758231 0.981086257758231
Actr1a ENSMUSG00000025228 0.731209535542991 0.731209535542991 0.110106890368078 0.330320671104235 0.41554694266428 0.62332041399642
Dctn2 ENSMUSG00000025410 0.108331328804162 0.162496993206243 0.0303954643087494 0.0911863929262483 0.902623612738164 0.902623612738164
Cct8 ENSMUSG00000025613 0.646901129062633 0.924533687312387 0.924533687312387 0.924533687312387 0.737203365937647 0.924533687312387
Pde6d ENSMUSG00000026239 0.794463171664167 0.794463171664167 0.00679151570218829 0.0203745471065649 0.758148459413747 0.794463171664167
Sdccag8 ENSMUSG00000026504 0.254543809199947 0.76363142759984 0.773230867926442 0.773230867926442 0.758152411594837 0.773230867926442
Odf2 ENSMUSG00000026790 0.681293113878968 0.852806589170061 0.852806589170061 0.852806589170061 0.569571937085256 0.852806589170061
Inpp5e ENSMUSG00000026925 0.955922188637634 0.955922188637634 0.658345397594748 0.955922188637634 0.588389207019042 0.955922188637634
Ssna1 ENSMUSG00000026966 0.0909968073490994 0.272990422047298 0.254614843086871 0.381922264630306 0.543015799557618 0.543015799557618
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Haus2 ENSMUSG00000027285 0.610513615328683 0.915770422993024 0.918270834159523 0.918270834159523 0.481993699034498 0.915770422993024
Gabpb1 ENSMUSG00000027361 0.871451333182253 0.871451333182253 0.713537561005164 0.871451333182253 0.672732818755147 0.871451333182253
Kif3b ENSMUSG00000027475 0.874564503154802 0.874564503154802 0.785361007627291 0.874564503154802 0.610531245929794 0.874564503154802
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Ift80 ENSMUSG00000027778 0.72534600556455 0.72534600556455 0.594010085589296 0.72534600556455 0.519716686456954 0.72534600556455
Kif24 ENSMUSG00000028438 0.540447942857581 0.868345300482773 0.6756105600846 0.868345300482773 0.868345300482773 0.868345300482773
Cep41 ENSMUSG00000029790 0.984257318519376 0.984257318519376 0.743194953250285 0.984257318519376 0.797526145321312 0.984257318519376
Cetn2 ENSMUSG00000031347 0.666973810860548 0.785311185544134 0.506956807101924 0.785311185544134 0.785311185544134 0.785311185544134
Pcm1 ENSMUSG00000031592 0.21107231064883 0.63321693194649 0.704683325300329 0.752179685909082 0.752179685909082 0.752179685909082
Dctn1 ENSMUSG00000031865 0.865200846099676 0.905728575654993 0.50446974304768 0.905728575654993 0.905728575654993 0.905728575654993
Cep63 ENSMUSG00000032534 0.426929353932834 0.640394030899251 0.386701443259813 0.640394030899251 0.874527652930211 0.874527652930211
Mks1 ENSMUSG00000034121 0.133166636948269 0.399499910844806 0.719435229766814 0.719435229766814 0.602181528550136 0.719435229766814
Traf3ip1 ENSMUSG00000034292 1 1 0.28924954509742 0.86774863529226 0.940229426343187 1
Ttc21b ENSMUSG00000034848 0.580318590242206 0.88078455733909 0.88078455733909 0.88078455733909 0.604963066891069 0.88078455733909
Tubg1 ENSMUSG00000035198 0.610523507905525 0.770229096195905 0.0822336056352081 0.246700816905624 0.770229096195905 0.770229096195905
Haus8 ENSMUSG00000035439 0.752177410523124 0.755172100979466 0.535228634806669 0.755172100979466 0.755172100979466 0.755172100979466
Bbs10 ENSMUSG00000035759 0.933951205228652 0.933951205228652 0.613291811915146 0.933951205228652 0.6469797881367 0.933951205228652
Bbs9 ENSMUSG00000035919 0.564241311190594 0.815820454637254 0.678483067359399 0.815820454637254 0.815820454637254 0.815820454637254
Cep135 ENSMUSG00000036403 0.734233377818182 0.977960637243456 0.749157033585928 0.977960637243456 0.977960637243456 0.977960637243456
Exoc1 ENSMUSG00000036435 0.415543130583432 0.770095312459101 0.770095312459101 0.770095312459101 0.56159350154872 0.770095312459101
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Cep250 ENSMUSG00000038241 0.852836376101353 0.9465102123595 0.9465102123595 0.9465102123595 0.743183828624343 0.9465102123595
Cdk5rap2 ENSMUSG00000039298 0.770212261279226 0.908874409129535 0.701767958416825 0.908874409129535 0.908874409129535 0.908874409129535
Cep78 ENSMUSG00000041491 0.965374013690382 0.965374013690382 0.710588562586299 0.965374013690382 0.908871734346741 0.965374013690382
C2cd3 ENSMUSG00000047248 0.489429390732886 0.604982556408182 0.138390379060489 0.415171137181468 0.604982556408182 0.604982556408182
Bbs12 ENSMUSG00000051444 0.61052689833357 0.764194744620874 0.764194744620874 0.764194744620874 0.436385723139687 0.764194744620874
Cep70 ENSMUSG00000056267 0.566916097551263 0.822000521616509 0.822000521616509 0.822000521616509 0.821996651788269 0.822000521616509
4922501C03Rik ENSMUSG00000056919 0.675543696009354 0.908841494951936 0.908841494951936 0.908841494951936 0.785248613234626 0.908841494951936
Sclt1 ENSMUSG00000059834 0.749181725715864 0.837391361537029 0.837391361537029 0.837391361537029 0.613301726166376 0.837391361537029
Exoc5 ENSMUSG00000061244 0.108322260304065 0.324966780912195 0.355026060691986 0.532539091037979 0.921401924246316 0.921401924246316
Hspb11 ENSMUSG00000063172 0.572228089471274 0.782285388744571 0.782285388744571 0.782285388744571 0.287412100258045 0.782285388744571
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Alms1 ENSMUSG00000063810 0.593934852596802 0.812771683964293 0.574983444300203 0.812771683964293 0.812771683964293 0.812771683964293
Tcp1 ENSMUSG00000068039 0.971656190495982 0.971656190495982 0.849725921700933 0.971656190495982 0.92451559146861 0.971656190495982
Exoc8 ENSMUSG00000074030 0.849737247415159 0.984252197087892 0.183285563776723 0.54985669133017 0.984252197087892 0.984252197087892
Bbip1 ENSMUSG00000084957 0.908868998529789 0.908868998529789 0.641192229278013 0.908868998529789 0.710527880564381 0.908868998529789

Regulation of cholesterol biosynthesis by SREBP (SREBF)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kpnb1 ENSMUSG00000001440 0.47906407146345 0.794254594886872 0.543049671438003 0.794254594886872 0.794254594886872 0.794254594886872
Srebf2 ENSMUSG00000022463 0.815777841667421 0.828081941890635 0.806663090983446 0.828081941890635 0.828081941890635 0.828081941890635
Mbtps1 ENSMUSG00000031835 0.126737032857096 0.380211098571289 0.417920674420203 0.626881011630305 0.722195456436019 0.722195456436019
Scap ENSMUSG00000032485 0.638259600294436 0.921361346942793 0.58031054623419 0.921361346942793 0.921361346942793 0.921361346942793
Mbtps2 ENSMUSG00000046873 0.120181267672012 0.360543803016036 0.309502130103456 0.464253195155184 0.868285830636168 0.868285830636168

Signaling by Rho GTPases, Miro GTPases and RHOBTB3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Arhgef18 ENSMUSG00000004568 0.630007088766582 0.678468382547835 0.464917015692904 0.678468382547835 0.678468382547835 0.678468382547835
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Nf2 ENSMUSG00000009073 0.509134401232616 0.763701601848925 0.352880397268822 0.763701601848925 0.782091421985515 0.782091421985515
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Bcr ENSMUSG00000009681 0.974807332533465 0.974807332533465 0.707597015236092 0.974807332533465 0.785355793137647 0.974807332533465
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Abr ENSMUSG00000017631 0.921398696121242 0.921398696121242 0.68140547807616 0.921398696121242 0.532618249869906 0.921398696121242
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Cdc37 ENSMUSG00000019471 0.325907383352763 0.325907383352763 0.00494180753989851 0.0148254226196955 0.198861511739873 0.298292267609809
Gopc ENSMUSG00000019861 0.722278617800551 0.871394736386296 0.843562744111195 0.871394736386296 0.871394736386296 0.871394736386296
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Rhobtb1 ENSMUSG00000019944 0.940116835372231 0.940116835372231 0.483972934063864 0.940116835372231 0.658089294075101 0.940116835372231
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Evl ENSMUSG00000021262 0.933943567381201 0.933943567381201 0.472181022477731 0.933943567381201 0.806668805723746 0.933943567381201
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Arhgef3 ENSMUSG00000021895 0.585781284449995 0.803601320738584 0.803601320738584 0.803601320738584 0.661231094337729 0.803601320738584
Rhobtb2 ENSMUSG00000022075 0.627243469059781 0.78839774175095 0.610520795499542 0.78839774175095 0.78839774175095 0.78839774175095
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Fgd4 ENSMUSG00000022788 0.126037570790604 0.189056356185906 0.0515046442054808 0.154513932616442 0.57759250018939 0.57759250018939
Arhgap31 ENSMUSG00000022799 0.313210241640468 0.82506476856873 0.574887689318174 0.82506476856873 0.82506476856873 0.82506476856873
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Ralbp1 ENSMUSG00000024096 0.9464972920431 0.949647232945353 0.215424404507368 0.646273213522105 0.949647232945353 0.949647232945353
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Arhgdia ENSMUSG00000025132 0.422341226463687 0.63351183969553 0.300219684414466 0.63351183969553 0.752082591720677 0.752082591720677
Rhot2 ENSMUSG00000025733 0.987391017626738 0.987391017626738 0.334384653255001 0.935701665663378 0.623801110442252 0.935701665663378
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Arhgap1 ENSMUSG00000027247 0.675317261972381 0.821888585649098 0.821888585649098 0.821888585649098 0.672639592639289 0.821888585649098
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Arhgef2 ENSMUSG00000028059 0.62164652975037 0.932469794625556 0.949650888105473 0.949650888105473 0.501952685652417 0.932469794625556
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Inpp5b ENSMUSG00000028894 0.831196617340709 0.831196617340709 0.722292545166494 0.831196617340709 0.646912568962143 0.831196617340709
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Rhof ENSMUSG00000029449 0.402125360206579 0.62154668744514 0.62154668744514 0.62154668744514 0.522279195645465 0.62154668744514
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Arhgap6 ENSMUSG00000031355 0.959060024490474 0.959060024490474 0.818887989448878 0.959060024490474 0.621423822417863 0.959060024490474
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Arhgap39 ENSMUSG00000033697 0.76417654805197 0.782305918406638 0.782305918406638 0.782305918406638 0.616029052249447 0.782305918406638
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Diap2 ENSMUSG00000034480 0.175701685912187 0.52710505773656 0.725354954128688 0.812803758241982 0.812803758241982 0.812803758241982
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Myl12b ENSMUSG00000034868 0.479455362371212 0.82648107226288 0.88699382740213 0.88699382740213 0.550987381508587 0.82648107226288
Rtkn ENSMUSG00000034930 0.535193579092383 0.802790368638574 0.911976049010146 0.911976049010146 0.499356641091065 0.802790368638574
Fam13b ENSMUSG00000036501 0.386789490054983 0.846394365955162 0.905753648703601 0.905753648703601 0.564262910636775 0.846394365955162
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Ppp1r14a ENSMUSG00000037166 0.915139717761997 0.915139717761997 0.0438631575789575 0.131589472736872 0.912009628398801 0.915139717761997
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Myo9a ENSMUSG00000039585 0.124119855366736 0.372359566100207 0.707604870104562 0.707604870104562 0.687168742001995 0.707604870104562
Prex1 ENSMUSG00000039621 0.596579726038014 0.773138356873972 0.365406823327955 0.773138356873972 0.773138356873972 0.773138356873972
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Arhgap12 ENSMUSG00000041225 0.0565671913329013 0.169701573998704 0.190088026358006 0.285132039537008 0.815865562234169 0.815865562234169
Arhgef11 ENSMUSG00000041977 0.949643133278126 0.949643133278126 0.918271561620946 0.949643133278126 0.868322629819108 0.949643133278126
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Fmnl1 ENSMUSG00000055805 0.984257146303892 0.984257146303892 0.859037017579714 0.984257146303892 0.794484712393298 0.984257146303892
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Arhgap22 ENSMUSG00000063506 0.837380833173117 0.896378438699332 0.896378438699332 0.896378438699332 0.436385671812208 0.896378438699332
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

Signaling by Rho GTPases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Arhgef18 ENSMUSG00000004568 0.630007088766582 0.678468382547835 0.464917015692904 0.678468382547835 0.678468382547835 0.678468382547835
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Nf2 ENSMUSG00000009073 0.509134401232616 0.763701601848925 0.352880397268822 0.763701601848925 0.782091421985515 0.782091421985515
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Bcr ENSMUSG00000009681 0.974807332533465 0.974807332533465 0.707597015236092 0.974807332533465 0.785355793137647 0.974807332533465
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Abr ENSMUSG00000017631 0.921398696121242 0.921398696121242 0.68140547807616 0.921398696121242 0.532618249869906 0.921398696121242
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Cdc37 ENSMUSG00000019471 0.325907383352763 0.325907383352763 0.00494180753989851 0.0148254226196955 0.198861511739873 0.298292267609809
Gopc ENSMUSG00000019861 0.722278617800551 0.871394736386296 0.843562744111195 0.871394736386296 0.871394736386296 0.871394736386296
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Rhobtb1 ENSMUSG00000019944 0.940116835372231 0.940116835372231 0.483972934063864 0.940116835372231 0.658089294075101 0.940116835372231
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Evl ENSMUSG00000021262 0.933943567381201 0.933943567381201 0.472181022477731 0.933943567381201 0.806668805723746 0.933943567381201
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Arhgef3 ENSMUSG00000021895 0.585781284449995 0.803601320738584 0.803601320738584 0.803601320738584 0.661231094337729 0.803601320738584
Rhobtb2 ENSMUSG00000022075 0.627243469059781 0.78839774175095 0.610520795499542 0.78839774175095 0.78839774175095 0.78839774175095
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Fgd4 ENSMUSG00000022788 0.126037570790604 0.189056356185906 0.0515046442054808 0.154513932616442 0.57759250018939 0.57759250018939
Arhgap31 ENSMUSG00000022799 0.313210241640468 0.82506476856873 0.574887689318174 0.82506476856873 0.82506476856873 0.82506476856873
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Ralbp1 ENSMUSG00000024096 0.9464972920431 0.949647232945353 0.215424404507368 0.646273213522105 0.949647232945353 0.949647232945353
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Arhgdia ENSMUSG00000025132 0.422341226463687 0.63351183969553 0.300219684414466 0.63351183969553 0.752082591720677 0.752082591720677
Rhot2 ENSMUSG00000025733 0.987391017626738 0.987391017626738 0.334384653255001 0.935701665663378 0.623801110442252 0.935701665663378
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Arhgap1 ENSMUSG00000027247 0.675317261972381 0.821888585649098 0.821888585649098 0.821888585649098 0.672639592639289 0.821888585649098
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Arhgef2 ENSMUSG00000028059 0.62164652975037 0.932469794625556 0.949650888105473 0.949650888105473 0.501952685652417 0.932469794625556
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Inpp5b ENSMUSG00000028894 0.831196617340709 0.831196617340709 0.722292545166494 0.831196617340709 0.646912568962143 0.831196617340709
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Rhof ENSMUSG00000029449 0.402125360206579 0.62154668744514 0.62154668744514 0.62154668744514 0.522279195645465 0.62154668744514
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Arhgap6 ENSMUSG00000031355 0.959060024490474 0.959060024490474 0.818887989448878 0.959060024490474 0.621423822417863 0.959060024490474
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Arhgap39 ENSMUSG00000033697 0.76417654805197 0.782305918406638 0.782305918406638 0.782305918406638 0.616029052249447 0.782305918406638
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Diap2 ENSMUSG00000034480 0.175701685912187 0.52710505773656 0.725354954128688 0.812803758241982 0.812803758241982 0.812803758241982
Sos2 ENSMUSG00000034801 0.0840905831114443 0.252271749334333 0.506662012311684 0.506662012311684 0.360994376445304 0.506662012311684
Myl12b ENSMUSG00000034868 0.479455362371212 0.82648107226288 0.88699382740213 0.88699382740213 0.550987381508587 0.82648107226288
Rtkn ENSMUSG00000034930 0.535193579092383 0.802790368638574 0.911976049010146 0.911976049010146 0.499356641091065 0.802790368638574
Fam13b ENSMUSG00000036501 0.386789490054983 0.846394365955162 0.905753648703601 0.905753648703601 0.564262910636775 0.846394365955162
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Ppp1r14a ENSMUSG00000037166 0.915139717761997 0.915139717761997 0.0438631575789575 0.131589472736872 0.912009628398801 0.915139717761997
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Myo9a ENSMUSG00000039585 0.124119855366736 0.372359566100207 0.707604870104562 0.707604870104562 0.687168742001995 0.707604870104562
Prex1 ENSMUSG00000039621 0.596579726038014 0.773138356873972 0.365406823327955 0.773138356873972 0.773138356873972 0.773138356873972
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Arhgap12 ENSMUSG00000041225 0.0565671913329013 0.169701573998704 0.190088026358006 0.285132039537008 0.815865562234169 0.815865562234169
Arhgef11 ENSMUSG00000041977 0.949643133278126 0.949643133278126 0.918271561620946 0.949643133278126 0.868322629819108 0.949643133278126
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Fmnl1 ENSMUSG00000055805 0.984257146303892 0.984257146303892 0.859037017579714 0.984257146303892 0.794484712393298 0.984257146303892
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Arhgap22 ENSMUSG00000063506 0.837380833173117 0.896378438699332 0.896378438699332 0.896378438699332 0.436385671812208 0.896378438699332
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

RHO GTPase Effectors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Dvl3 ENSMUSG00000003233 0.271198013962619 0.493255840010792 0.328837226673862 0.493255840010792 0.996848463263402 0.996848463263402
Ppp1cc ENSMUSG00000004455 0.94650517299881 0.94650517299881 0.404423862280798 0.94650517299881 0.93080650192298 0.94650517299881
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Kif5b ENSMUSG00000006740 0.332799292083218 0.990553639240077 0.849745868497015 0.990553639240077 0.990553639240077 0.990553639240077
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Dynll1 ENSMUSG00000009013 0.376025787563858 0.726699890151163 0.921401626820533 0.921401626820533 0.484466593434109 0.726699890151163
Nf2 ENSMUSG00000009073 0.509134401232616 0.763701601848925 0.352880397268822 0.763701601848925 0.782091421985515 0.782091421985515
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Taok1 ENSMUSG00000017291 0.159682377581876 0.479047132745627 0.494376554725788 0.741564832088682 0.918261248041039 0.918261248041039
Ppp2r5c ENSMUSG00000017843 0.580131596247932 0.649617900902189 0.140423580778014 0.421270742334041 0.649617900902189 0.649617900902189
Ywhab ENSMUSG00000018326 0.927675102346655 0.927675102346655 0.332796367681871 0.927675102346655 0.880788692454716 0.927675102346655
Dync1h1 ENSMUSG00000018707 0.776204794690532 0.776204794690532 0.577609520010916 0.776204794690532 0.716341166005056 0.776204794690532
Ywhah ENSMUSG00000018965 0.638468243045487 0.779286699539649 0.384608551878596 0.779286699539649 0.779286699539649 0.779286699539649
Gopc ENSMUSG00000019861 0.722278617800551 0.871394736386296 0.843562744111195 0.871394736386296 0.871394736386296 0.871394736386296
Ppp1r12a ENSMUSG00000019907 0.0880388196807963 0.264116459042389 0.388973158986131 0.583459738479196 0.746187391806631 0.746187391806631
Actr2 ENSMUSG00000020152 0.517172302347769 0.961984387548559 0.962229082220697 0.962229082220697 0.641322925032373 0.961984387548559
Xpo1 ENSMUSG00000020290 0.332782070083523 0.548072702478715 0.890138385029295 0.890138385029295 0.365381801652477 0.548072702478715
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ska2 ENSMUSG00000020492 0.687075741610962 0.924541390694809 0.896350149482282 0.924541390694809 0.924541390694809 0.924541390694809
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Dvl2 ENSMUSG00000020888 0.722390037589126 0.908883333499776 0.54306558999052 0.908883333499776 0.908883333499776 0.908883333499776
Evl ENSMUSG00000021262 0.933943567381201 0.933943567381201 0.472181022477731 0.933943567381201 0.806668805723746 0.933943567381201
Kif2a ENSMUSG00000021693 0.175695035650405 0.527085106951214 0.785357055874038 0.821983750537905 0.821983750537905 0.821983750537905
Ywhaz ENSMUSG00000022285 0.86211735109251 0.86211735109251 0.707648278664338 0.86211735109251 0.752163515924987 0.86211735109251
Rangap1 ENSMUSG00000022391 0.452903404051534 0.679355106077301 0.105722967927757 0.317168903783271 0.874563711466469 0.874563711466469
Tuba1b ENSMUSG00000023004 0.915139057022887 0.915139057022887 0.395501425896349 0.75671233527307 0.504474890182047 0.75671233527307
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Men1 ENSMUSG00000024947 0.779236786336851 0.837335186621709 0.672678704926201 0.837335186621709 0.837335186621709 0.837335186621709
Ahctf1 ENSMUSG00000026491 0.252941845832037 0.75882553749611 0.693007534062019 0.987404502885454 0.987404502885454 0.987404502885454
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Dync1i2 ENSMUSG00000027012 0.652636356028928 0.818916078046636 0.764182068804356 0.818916078046636 0.818916078046636 0.818916078046636
Mapre1 ENSMUSG00000027479 0.524728095014347 0.537831528427772 0.402074560155799 0.537831528427772 0.537831528427772 0.537831528427772
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Nudc ENSMUSG00000028851 0.815795614142609 0.908855518500939 0.194139647627995 0.582418942883986 0.908855518500939 0.908855518500939
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Dvl1 ENSMUSG00000029071 0.446612836223607 0.767866289088682 0.511910859392455 0.767866289088682 0.796998839149728 0.796998839149728
Cenpc1 ENSMUSG00000029253 0.501875973901972 0.899499454697685 0.899499454697685 0.899499454697685 0.669813305481104 0.899499454697685
Mad1l1 ENSMUSG00000029554 0.734242004454943 0.734242004454943 0.155007467566764 0.465022402700292 0.604951605874172 0.734242004454943
Arpc1a ENSMUSG00000029621 0.203879624549745 0.305819436824618 0.135221561481287 0.305819436824618 0.553631745195638 0.553631745195638
Wasl ENSMUSG00000029684 0.221445938858453 0.66433781657536 0.666953669280098 0.862121055698246 0.862121055698246 0.862121055698246
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dync1li1 ENSMUSG00000032435 0.974812844402363 0.974812844402363 0.203924522602104 0.611773567806313 0.791422171294165 0.974812844402363
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Diap2 ENSMUSG00000034480 0.175701685912187 0.52710505773656 0.725354954128688 0.812803758241982 0.812803758241982 0.812803758241982
Myl12b ENSMUSG00000034868 0.479455362371212 0.82648107226288 0.88699382740213 0.88699382740213 0.550987381508587 0.82648107226288
Rtkn ENSMUSG00000034930 0.535193579092383 0.802790368638574 0.911976049010146 0.911976049010146 0.499356641091065 0.802790368638574
Cenpt ENSMUSG00000036672 0.743150501446238 0.743150501446238 0.123118196818908 0.369354590456724 0.369602197233801 0.554403295850701
Tubb4b ENSMUSG00000036752 0.373867741850519 0.560801612775778 0.000760031278418325 0.00228009383525498 0.908877630714294 0.908877630714294
Ppp1r14a ENSMUSG00000037166 0.915139717761997 0.915139717761997 0.0438631575789575 0.131589472736872 0.912009628398801 0.915139717761997
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Mis12 ENSMUSG00000040599 0.868329959727189 0.868329959727189 0.664076242207987 0.868329959727189 0.849720863270774 0.868329959727189
Klc3 ENSMUSG00000040714 0.32266615683745 0.720186992783289 0.877111526150201 0.877111526150201 0.480124661855526 0.720186992783289
Rcc2 ENSMUSG00000040945 0.464827859456458 0.687193667130749 0.262865641725828 0.687193667130749 0.687193667130749 0.687193667130749
Mkl1 ENSMUSG00000042292 0.927671526615282 0.952794686023589 0.952794686023589 0.952794686023589 0.940224803519338 0.952794686023589
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Fmnl1 ENSMUSG00000055805 0.984257146303892 0.984257146303892 0.859037017579714 0.984257146303892 0.794484712393298 0.984257146303892
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
B9d2 ENSMUSG00000063439 0.241595125927166 0.560768868635745 0.37384591242383 0.560768868635745 0.624402196991205 0.624402196991205
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589
Ywhaq ENSMUSG00000076432 0.41091296881274 0.933927937593932 0.933927937593932 0.933927937593932 0.646989051670587 0.933927937593932
Arpc4 ENSMUSG00000079426 0.0689653526980142 0.108131178835656 0.0720874525571038 0.108131178835656 0.899482472895612 0.899482472895612

Post-transcriptional silencing by small RNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ago2 ENSMUSG00000036698 0.481894144503412 0.987402845972038 0.846656056497879 0.987402845972038 0.987402845972038 0.987402845972038
Ago1 ENSMUSG00000041530 0.924502000524229 0.924502000524229 0.918254215470046 0.924502000524229 0.740051340943326 0.924502000524229
Ago4 ENSMUSG00000042500 0.661114457350717 0.940210895276645 0.828130337550788 0.940210895276645 0.940210895276645 0.940210895276645
Tnrc6b ENSMUSG00000047888 0.746186023227431 0.746186023227431 0.704714294857786 0.746186023227431 0.64982873699181 0.746186023227431
Tnrc6a ENSMUSG00000052707 0.843558416051339 0.843558416051339 0.408919705164051 0.843558416051339 0.773228059504463 0.843558416051339

APC-Cdc20 mediated degradation of Nek2A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Bub3 ENSMUSG00000066979 0.849745885074589 0.849745885074589 0.815871054491825 0.849745885074589 0.445789115612548 0.849745885074589

Nonhomologous End-Joining (NHEJ)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Paxip1 ENSMUSG00000002221 0.843499529111168 0.940196430274366 0.701636481517852 0.940196430274366 0.940196430274366 0.940196430274366
Pias4 ENSMUSG00000004934 0.395276569258342 0.734182200604005 0.666935622682266 0.734182200604005 0.734182200604005 0.734182200604005
Rnf168 ENSMUSG00000014074 0.309558633031852 0.928675899095555 0.893242859198096 0.968517862330212 0.968517862330212 0.968517862330212
Prkdc ENSMUSG00000022672 0.690079375349356 0.921400052157186 0.912011242765191 0.921400052157186 0.921400052157186 0.921400052157186
Kat5 ENSMUSG00000024926 0.532576729379491 0.843537339647269 0.74020830836884 0.843537339647269 0.843537339647269 0.843537339647269
Poll ENSMUSG00000025218 0.0265647205428424 0.0398470808142636 0.0126226286012384 0.0378678858037152 0.411124104047638 0.411124104047638
Sumo1 ENSMUSG00000026021 0.404406189172736 0.730433525315878 0.486955683543919 0.730433525315878 0.834309100018087 0.834309100018087
Dclre1c ENSMUSG00000026648 0.791349536535927 0.791349536535927 0.183165715330873 0.549497145992619 0.545547743610266 0.791349536535927
Herc2 ENSMUSG00000030451 0.577570073447967 0.779226958239253 0.779226958239253 0.779226958239253 0.71935917418063 0.779226958239253
Atm ENSMUSG00000034218 0.899488368934474 0.899488368934474 0.630033287142581 0.899488368934474 0.865235736237353 0.899488368934474
Rif1 ENSMUSG00000036202 0.289206890832308 0.433810336248461 0.249649284946705 0.433810336248461 0.719440962207448 0.719440962207448
Lig4 ENSMUSG00000049717 0.0926013994713989 0.277804198414197 0.94961238758366 0.94961238758366 0.812692402337864 0.94961238758366
H2afx ENSMUSG00000049932 0.962216009074329 0.962216009074329 0.0733267212538232 0.21998016376147 0.591168121265285 0.886752181897927
Whsc1 ENSMUSG00000057406 0.825069381300983 0.825069381300983 0.678507718402475 0.825069381300983 0.761181785649161 0.825069381300983
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Rnf8 ENSMUSG00000090083 0.373902193619431 0.771928871495718 0.514619247663812 0.771928871495718 0.803609271295858 0.803609271295858
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502
RNF8 ENSMUSG00000098374 0.871420787314358 0.871420787314358 0.202452565082624 0.607357695247873 0.821966075181601 0.871420787314358

Mitotic G1 phase and G1/S transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.70179412514195 0.78232381193193 0.78232381193193 0.78232381193193 0.693020000677428 0.78232381193193
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
E2f3 ENSMUSG00000016477 0.924539651969489 0.924539651969489 0.782318930162624 0.924539651969489 0.422428088982043 0.924539651969489
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Ppp2r2a ENSMUSG00000022052 0.687158313389731 0.687158313389731 0.604952897306054 0.687158313389731 0.486739111210487 0.687158313389731
Dyrk1a ENSMUSG00000022897 0.356444805291483 0.761099790833155 0.761099790833155 0.761099790833155 0.618254556879701 0.761099790833155
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Abl1 ENSMUSG00000026842 0.621367381545012 0.932051072317517 0.604958466461463 0.932051072317517 0.95275762452819 0.95275762452819
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Cdc7 ENSMUSG00000029283 0.905754675088245 0.937088160291987 0.937088160291987 0.937088160291987 0.758177847489751 0.937088160291987
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Rbl2 ENSMUSG00000031666 0.675587593032726 0.788370746960756 0.577667967504099 0.788370746960756 0.788370746960756 0.788370746960756
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Lin37 ENSMUSG00000036845 0.0665870101587646 0.0998805152381469 0.0175068864312451 0.0525206592937352 0.698862462776113 0.698862462776113
Tfdp1 ENSMUSG00000038482 0.809653003835044 0.930775251483381 0.484472456670062 0.930775251483381 0.930775251483381 0.930775251483381
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Cables1 ENSMUSG00000040957 0.971663259417754 0.971663259417754 0.499395893797283 0.971663259417754 0.912003502782391 0.971663259417754
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

CDK-mediated phosphorylation and removal of Cdc6

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

S Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpa1 ENSMUSG00000000751 0.646904807607947 0.646904807607947 0.0926011051171329 0.277803315351399 0.371554195933857 0.557331293900785
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Mnat1 ENSMUSG00000021103 0.0858206213008767 0.128730931951315 0.0526803223425382 0.128730931951315 0.610007654929554 0.610007654929554
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Rad21 ENSMUSG00000022314 0.514398921885326 0.629858245535903 0.443396515834477 0.629858245535903 0.629858245535903 0.629858245535903
Smc3 ENSMUSG00000024974 0.319085946333781 0.686476541641658 0.457651027761105 0.686476541641658 0.91825303258251 0.91825303258251
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Orc2 ENSMUSG00000026037 0.69299633559974 0.912004647763178 0.912004647763178 0.912004647763178 0.725354748086056 0.912004647763178
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Orc4 ENSMUSG00000026761 0.48681503741876 0.899464823246064 0.831229944997829 0.899464823246064 0.899464823246064 0.899464823246064
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Cdc25b ENSMUSG00000027330 0.290997133150149 0.872991399450447 0.893258961662429 0.893258961662429 0.764166348976125 0.893258961662429
Mcm8 ENSMUSG00000027353 0.707563812079892 0.94648402197815 0.837341584470403 0.94648402197815 0.94648402197815 0.94648402197815
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Orc5 ENSMUSG00000029012 0.707642545977525 0.962228930530315 0.719421602556229 0.962228930530315 0.962228930530315 0.962228930530315
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Pole4 ENSMUSG00000030042 0.984246547699098 0.984246547699098 0.026539019775054 0.079617059325162 0.259442106980895 0.389163160471342
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Wee1 ENSMUSG00000031016 0.627200135584393 0.627200135584393 0.395493172758422 0.627200135584393 0.474498623153614 0.627200135584393
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Stag1 ENSMUSG00000037286 0.522317012109436 0.783475518164153 0.192807567820902 0.578422703462707 0.993702439164909 0.993702439164909
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Orc3 ENSMUSG00000040044 0.880774237490208 0.880774237490208 0.0836575340241302 0.250972602072391 0.75816363892022 0.880774237490208
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Cables1 ENSMUSG00000040957 0.971663259417754 0.971663259417754 0.499395893797283 0.971663259417754 0.912003502782391 0.971663259417754
Smc1a ENSMUSG00000041133 0.404407241186334 0.606610861779501 0.219899946452865 0.606610861779501 0.713501310089134 0.713501310089134
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Cdk7 ENSMUSG00000069089 0.710581523574203 0.80668526980909 0.785357546932174 0.80668526980909 0.80668526980909 0.80668526980909
Ccnd1 ENSMUSG00000070348 0.187336376646231 0.562009129938693 0.607654777560625 0.797476138445346 0.797476138445346 0.797476138445346
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Rasa1 ENSMUSG00000021549 0.222896992458366 0.376945323539439 0.251296882359626 0.376945323539439 0.825080354293345 0.825080354293345
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002

ERKs are inactivated

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334

Signaling by FGFR2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Frs2 ENSMUSG00000020170 0.652661340403672 0.88701835685625 0.88701835685625 0.88701835685625 0.752176018491418 0.88701835685625
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Tial1 ENSMUSG00000030846 0.543088630633855 0.912011956971666 0.912011956971666 0.912011956971666 0.822004273936228 0.912011956971666
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Tia1 ENSMUSG00000071337 0.940204367651885 0.940204367651885 0.283687691377767 0.8510630741333 0.764190476983403 0.940204367651885
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Toll Like Receptor 9 (TLR9) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mapk7 ENSMUSG00000001034 0.952781077433445 0.987403200477085 0.912000273108574 0.987403200477085 0.987403200477085 0.987403200477085
Map2k7 ENSMUSG00000002948 0.596627189766289 0.894940784649434 0.336772057096951 0.894940784649434 0.987399962396895 0.987399962396895
Ppp2cb ENSMUSG00000009630 0.713528721332158 0.883903120329858 0.540469583658092 0.883903120329858 0.883903120329858 0.883903120329858
Zfyve20 ENSMUSG00000014550 0.675594907473703 0.758163822103712 0.758163822103712 0.758163822103712 0.67561226874794 0.758163822103712
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Peli1 ENSMUSG00000020134 0.238360125974115 0.715080377922345 0.710596774118559 0.794473179970104 0.794473179970104 0.794473179970104
Ppp2ca ENSMUSG00000020349 0.767152163300617 0.803619605577203 0.803619605577203 0.803619605577203 0.782306937626552 0.803619605577203
Rps6ka5 ENSMUSG00000021180 0.424827348080109 0.949652263497228 0.949652263497228 0.949652263497228 0.67272854849133 0.949652263497228
Fos ENSMUSG00000021250 0.0329335742234713 0.0988007226704138 0.564235039785233 0.846352559677849 0.981103327800893 0.981103327800893
Tab1 ENSMUSG00000022414 0.00520444699366055 0.0156133409809817 0.0996028671504475 0.149404300725671 0.23972801161307 0.23972801161307
App ENSMUSG00000022892 0.669837081661211 0.704724196773938 0.332776383296367 0.704724196773938 0.704724196773938 0.704724196773938
Creb1 ENSMUSG00000025958 0.106576632501911 0.319729897505733 0.289232841038621 0.433849261557932 0.695919699274889 0.695919699274889
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Map3k7 ENSMUSG00000028284 0.202486227320732 0.607458681962196 0.710601774784774 0.874561544663849 0.874561544663849 0.874561544663849
Cul1 ENSMUSG00000029686 0.921402816503409 0.993702462366167 0.849739518882618 0.993702462366167 0.993702462366167 0.993702462366167
Irak1 ENSMUSG00000031392 0.987404896622702 0.987404896622702 0.905749469505611 0.987404896622702 0.77928547493353 0.987404896622702
Dusp4 ENSMUSG00000031530 0.831174084461113 0.831174084461113 0.669769523069885 0.831174084461113 0.509482121347959 0.831174084461113
Ppp2r1b ENSMUSG00000032058 0.927565892346948 0.927565892346948 0.556068121954809 0.927565892346948 0.751889538117095 0.927565892346948
Pik3r4 ENSMUSG00000032571 0.484458433435207 0.484458433435207 0.122132198489741 0.366396595469222 0.376008311159676 0.484458433435207
Pik3c3 ENSMUSG00000033628 0.749128839908729 0.855936707046403 0.855936707046403 0.855936707046403 0.459965701025435 0.855936707046403
Tab3 ENSMUSG00000035476 0.334634039301788 0.843502394766919 0.843502394766919 0.843502394766919 0.574862799578782 0.843502394766919
Eea1 ENSMUSG00000036499 0.00897735345572907 0.0269320603671872 0.0519013669945581 0.0778520504918372 0.85902223489798 0.85902223489798
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dusp7 ENSMUSG00000053716 0.902626468763423 0.924540659940838 0.88390185900298 0.924540659940838 0.924540659940838 0.924540659940838
Ppp2r5d ENSMUSG00000059409 0.776225797897746 0.776225797897746 0.232108600297442 0.696325800892326 0.681405545344699 0.776225797897746
Tnip2 ENSMUSG00000059866 0.367491497410191 0.551237246115287 0.996850707796632 0.996850707796632 0.247959754568764 0.551237246115287
Mapk3 ENSMUSG00000063065 0.484423932443715 0.737877019121092 0.491918012747394 0.737877019121092 0.852839917479334 0.852839917479334
Ube2n ENSMUSG00000074781 0.352947646492817 0.974812937173271 0.767183662851989 0.974812937173271 0.974812937173271 0.974812937173271
Ube2v1 ENSMUSG00000078923 0.707651456421661 0.707651456421661 0.0690119256001669 0.207035776800501 0.649779661098828 0.707651456421661

Glucose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup214 ENSMUSG00000001855 0.163299078148857 0.244948617223285 0.0957557562871322 0.244948617223285 0.918265423055621 0.918265423055621
Ranbp2 ENSMUSG00000003226 0.0581043513513683 0.174313054054105 0.235178677226885 0.352768015840327 0.740188195916636 0.740188195916636
Tpr ENSMUSG00000006005 0.719442222697042 0.825059924807163 0.698843488795044 0.825059924807163 0.825059924807163 0.825059924807163
Pgam1 ENSMUSG00000011752 0.852801192111818 0.852801192111818 0.201046044735963 0.60313813420789 0.818870648703071 0.852801192111818
Slc25a13 ENSMUSG00000015112 0.965368460722684 0.965368460722684 0.770199838480197 0.965368460722684 0.698799543714873 0.965368460722684
Nup85 ENSMUSG00000020739 0.149221334484064 0.223832001726096 0.0496332144849179 0.148899643454754 0.429393992796372 0.429393992796372
Pfkp ENSMUSG00000021196 0.952770262223643 0.952770262223643 0.924525384843973 0.952770262223643 0.921371604444614 0.952770262223643
Nup153 ENSMUSG00000021374 0.911980348925713 0.911980348925713 0.731266894873245 0.911980348925713 0.672657582583903 0.911980348925713
Fbp2 ENSMUSG00000021456 0.936625756886819 0.936625756886819 0.46141901392199 0.904917352190218 0.603278234793479 0.904917352190218
Nup155 ENSMUSG00000022142 0.178158895739624 0.399555584783583 0.266370389855722 0.399555584783583 0.52482890455904 0.52482890455904
Pfkfb1 ENSMUSG00000025271 0.588492130656257 0.882738195984386 0.38406707812773 0.882738195984386 0.905667774593432 0.905667774593432
Nup35 ENSMUSG00000026999 0.0239379484814667 0.0718138454444001 0.218414826234238 0.327622239351357 0.443352231726257 0.443352231726257
Rae1 ENSMUSG00000027509 0.599275609249078 0.758077129836248 0.527379162443622 0.758077129836248 0.758077129836248 0.758077129836248
Ndc1 ENSMUSG00000028614 0.161942726983277 0.48582818094983 0.719440361968342 0.719440361968342 0.532575491845359 0.719440361968342
Gnpda2 ENSMUSG00000029209 0.106379091118 0.182461971255547 0.121641314170365 0.182461971255547 0.905674432244613 0.905674432244613
Nup210 ENSMUSG00000030091 0.908870660314649 0.908870660314649 0.380312555500998 0.826395577561958 0.550930385041306 0.826395577561958
Nup93 ENSMUSG00000032939 0.469659289250454 0.479464605007876 0.271553887811893 0.479464605007876 0.479464605007876 0.479464605007876
G6pc3 ENSMUSG00000034793 0.175411584724297 0.263117377086445 0.124108250719009 0.263117377086445 0.96534228681455 0.96534228681455
Nup54 ENSMUSG00000034826 0.278337945774262 0.776178940217337 0.728299129759422 0.776178940217337 0.776178940217337 0.776178940217337
Nup205 ENSMUSG00000038759 0.553616007909162 0.830424011863742 0.965372850763817 0.965372850763817 0.517154544853595 0.830424011863742
Bpgm ENSMUSG00000038871 0.582227323512959 0.930582178794828 0.803306944610457 0.930582178794828 0.930582178794828 0.930582178794828
Nup133 ENSMUSG00000039509 0.535132075635122 0.535132075635122 0.0642593485495583 0.192778045648675 0.20236519952291 0.303547799284365
Pck2 ENSMUSG00000040618 0.257893691186856 0.386840536780284 0.201052471017059 0.386840536780284 0.812767660690678 0.812767660690678
Nup88 ENSMUSG00000040667 0.890139433199229 0.955937943200441 0.955937943200441 0.955937943200441 0.635663482593123 0.955937943200441
Nup188 ENSMUSG00000052533 0.429184180892667 0.643776271339001 0.411119600744046 0.643776271339001 0.788279857838799 0.788279857838799
Nup107 ENSMUSG00000052798 0.803615308776834 0.803615308776834 0.580391092542569 0.803615308776834 0.610457955580274 0.803615308776834
Pom121 ENSMUSG00000053293 0.734229007049331 0.981107332358091 0.981107332358091 0.981107332358091 0.684291851718935 0.981107332358091
Eno1 ENSMUSG00000063524 0.564113347358687 0.564113347358687 0.242910138014227 0.538403804399347 0.358935869599564 0.538403804399347
Nupl1 ENSMUSG00000063895 0.0319413817139346 0.0958241451418038 0.684169252559196 0.684169252559196 0.602148039786902 0.684169252559196

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Fzr1 ENSMUSG00000020235 0.330354593144614 0.495531889716921 0.0525006417070584 0.157501925121175 0.754852075314465 0.754852075314465
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Skp2 ENSMUSG00000054115 0.249343946605829 0.666707269317598 0.501773764616441 0.666707269317598 0.666707269317598 0.666707269317598
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

APC/C:Cdc20 mediated degradation of Cyclin B

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617

FGFR2 alternative splicing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2f1 ENSMUSG00000002658 0.212437860520629 0.357586812879498 0.238391208586332 0.357586812879498 0.930800027026957 0.930800027026957
Polr2e ENSMUSG00000004667 0.198188304708198 0.198188304708198 0.179168246622323 0.198188304708198 0.0773942344885721 0.198188304708198
Hnrnph1 ENSMUSG00000007850 0.593971319402859 0.803616361519006 0.764182605523499 0.803616361519006 0.803616361519006 0.803616361519006
Ncbp2 ENSMUSG00000022774 0.604900624589868 0.918263094586088 0.918252677706236 0.918263094586088 0.918263094586088 0.918263094586088
Polr2d ENSMUSG00000024258 0.140366709308086 0.421100127924258 0.373616784595149 0.560425176892723 0.590989031880404 0.590989031880404
Ncbp1 ENSMUSG00000028330 0.321036708324044 0.955936355725189 0.955936355725189 0.955936355725189 0.646953280116664 0.955936355725189
Polr2b ENSMUSG00000029250 0.276792049165963 0.734258112879843 0.701790446357526 0.734258112879843 0.734258112879843 0.734258112879843
Tial1 ENSMUSG00000030846 0.543088630633855 0.912011956971666 0.912011956971666 0.912011956971666 0.822004273936228 0.912011956971666
Polr2l ENSMUSG00000038489 0.0294311878095515 0.0441467817143273 0.00137286638861021 0.00411859916583063 0.164297493347321 0.164297493347321
Hnrnpa1 ENSMUSG00000046434 0.824979617388229 0.952793485738899 0.315174206734161 0.945522620202483 0.952793485738899 0.952793485738899
Tia1 ENSMUSG00000071337 0.940204367651885 0.940204367651885 0.283687691377767 0.8510630741333 0.764190476983403 0.940204367651885
Polr2g ENSMUSG00000071662 0.330730815515514 0.8105547988048 0.855880256851693 0.855880256851693 0.540369865869867 0.8105547988048

Regulation of TP53 Activity through Acetylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Pip4k2c ENSMUSG00000025417 0.415515138279696 0.623272707419544 0.289046752530836 0.623272707419544 0.930810740453744 0.930810740453744
Pip4k2a ENSMUSG00000026737 0.574967845759316 0.737238898686309 0.737238898686309 0.737238898686309 0.491865076476834 0.737238898686309
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Mbd3 ENSMUSG00000035478 0.127028313403594 0.190542470105391 0.00713432650413622 0.0214029795124087 0.927676841699906 0.927676841699906
Tmem55b ENSMUSG00000035953 0.420240190828089 0.698861822902581 0.624445760249808 0.698861822902581 0.698861822902581 0.698861822902581
Gatad2b ENSMUSG00000042390 0.251212905944431 0.753638717833294 0.583068554251309 0.874602831376964 0.933942029189689 0.933942029189689
Ep300 ENSMUSG00000055024 0.280281203174992 0.74537925757993 0.496919505053287 0.74537925757993 0.877649855204843 0.877649855204843
Rbbp4 ENSMUSG00000057236 0.384502987566139 0.576754481349208 0.27670915510208 0.576754481349208 0.984255320120632 0.984255320120632
Ing2 ENSMUSG00000063049 0.806687766565289 0.81584453769313 0.580300215359064 0.81584453769313 0.81584453769313 0.81584453769313
Chd4 ENSMUSG00000063870 0.50939259475567 0.955921750769624 0.806684888939472 0.955921750769624 0.955921750769624 0.955921750769624

APC/C:Cdc20 mediated degradation of Securin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmd4 ENSMUSG00000005625 0.0611606475423253 0.0917409713134879 0.00483234332630305 0.0144970299789091 0.177989905775648 0.177989905775648
Anapc1 ENSMUSG00000014355 0.426969942048089 0.731141100910765 0.566748238205846 0.731141100910765 0.731141100910765 0.731141100910765
Psmd3 ENSMUSG00000017221 0.0583745528615543 0.0875618292923315 0.010839748804544 0.0325192464136321 0.452337700918659 0.452337700918659
Psmb6 ENSMUSG00000018286 0.238236184050163 0.558456482386937 0.558456482386937 0.558456482386937 0.506583124592314 0.558456482386937
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Anapc16 ENSMUSG00000020107 0.179437512808262 0.538312538424787 0.624338896843928 0.936508345265891 0.943368812574716 0.943368812574716
Cdc27 ENSMUSG00000020687 0.175699501532802 0.481499266163077 0.320999510775385 0.481499266163077 0.981107870184178 0.981107870184178
Psma6 ENSMUSG00000021024 0.0946623271628396 0.141993490744259 0.000877879187597164 0.00263363756279149 0.90569833146609 0.90569833146609
Ube2e1 ENSMUSG00000021774 0.946507457287881 0.968520254726342 0.388882191973804 0.968520254726342 0.968520254726342 0.968520254726342
Anapc11 ENSMUSG00000025135 0.30561519648572 0.45842279472858 0.0496468727313296 0.148940618193989 0.764102414868302 0.764102414868302
Psmd13 ENSMUSG00000025487 0.126672497675296 0.380017493025888 0.99370254110792 0.99370254110792 0.63806772326474 0.957101584897109
Psmb7 ENSMUSG00000026750 0.713542240501056 0.713542240501056 0.285390624574052 0.713542240501056 0.666792125001217 0.713542240501056
Psmd5 ENSMUSG00000026869 0.561457308664283 0.797482291731842 0.797482291731842 0.797482291731842 0.484473678152681 0.797482291731842
Psmd14 ENSMUSG00000026914 0.404429858165849 0.896381360674897 0.707649587165186 0.896381360674897 0.896381360674897 0.896381360674897
Anapc2 ENSMUSG00000026965 0.348703632016991 0.404253273880076 0.147052873475054 0.404253273880076 0.404253273880076 0.404253273880076
Psmc2 ENSMUSG00000028932 0.063671654848111 0.191014964544333 0.499125834779391 0.499125834779391 0.33639181192011 0.499125834779391
Anapc4 ENSMUSG00000029176 0.624412498646381 0.624412498646381 0.621650113566787 0.624412498646381 0.583112091277871 0.624412498646381
Psmd9 ENSMUSG00000029440 0.206580480706135 0.235035331160385 0.0496424059690297 0.148927217907089 0.235035331160385 0.235035331160385
Anapc7 ENSMUSG00000029466 0.124928294504499 0.374784883513497 0.257453946236557 0.386180919354835 0.646976736892801 0.646976736892801
Psmc4 ENSMUSG00000030603 0.00819343850350702 0.0122901577552605 0.00102766219836321 0.00308298659508963 0.101531331466498 0.101531331466498
Psmf1 ENSMUSG00000032869 0.419769815857563 0.577374550693117 0.0836078221755822 0.250823466526747 0.577374550693117 0.577374550693117
Anapc10 ENSMUSG00000036977 0.174438841698874 0.35042373722421 0.23361582481614 0.35042373722421 0.977957721505983 0.977957721505983
Cdc16 ENSMUSG00000038416 0.499379291689215 0.749068937533822 0.305784273133731 0.749068937533822 0.977958329354324 0.977958329354324
Psme4 ENSMUSG00000040850 0.737148837422996 0.927660038808978 0.927660038808978 0.927660038808978 0.915126084532616 0.927660038808978
Ube2s ENSMUSG00000060860 0.949486526340617 0.949486526340617 0.034312114420599 0.102936343261797 0.665916714491549 0.949486526340617
Psme3 ENSMUSG00000078652 0.388795117763831 0.583192676645746 0.330806237111951 0.583192676645746 0.949626848276883 0.949626848276883

mRNA decay by 3’ to 5’ exoribonuclease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nt5c3b ENSMUSG00000017176 0.840372799791322 0.840393572668707 0.840393572668707 0.840393572668707 0.716475716566378 0.840393572668707
Exosc9 ENSMUSG00000027714 0.561593764009539 0.842390646014309 0.522179239170174 0.842390646014309 0.971662047887827 0.971662047887827
Exosc8 ENSMUSG00000027752 0.271556682590171 0.593319980414375 0.828151875595968 0.828151875595968 0.395546653609583 0.593319980414375
Dis3 ENSMUSG00000033166 0.367523954072879 0.921405248187103 0.921405248187103 0.921405248187103 0.868335554697988 0.921405248187103
Ttc37 ENSMUSG00000033991 0.209479265727045 0.314218898590567 0.161957506810136 0.314218898590567 0.602092125220025 0.602092125220025
Exosc4 ENSMUSG00000034259 0.0201677895647318 0.0302516843470977 6.01517045479488e-05 0.000180455113643846 0.773247026643611 0.773247026643611
Exosc1 ENSMUSG00000034321 0.262955495630135 0.394433243445202 0.0329606160621557 0.098881848186467 0.740203609354288 0.740203609354288
Exosc2 ENSMUSG00000039356 0.550908916717947 0.815837608721388 0.746141231105642 0.815837608721388 0.815837608721388 0.815837608721388
Skiv2l ENSMUSG00000040356 0.320818972045176 0.481228458067763 0.303842486320552 0.481228458067763 0.812719792582066 0.812719792582066

RHO GTPase cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Cdc37 ENSMUSG00000019471 0.325907383352763 0.325907383352763 0.00494180753989851 0.0148254226196955 0.198861511739873 0.298292267609809
Rhobtb1 ENSMUSG00000019944 0.940116835372231 0.940116835372231 0.483972934063864 0.940116835372231 0.658089294075101 0.940116835372231
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Rhobtb2 ENSMUSG00000022075 0.627243469059781 0.78839774175095 0.610520795499542 0.78839774175095 0.78839774175095 0.78839774175095
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479

RHOBTB GTPase Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccne1 ENSMUSG00000002068 0.933803417013863 0.933803417013863 0.271475675930029 0.814427027790086 0.871152586017793 0.933803417013863
Cdc37 ENSMUSG00000019471 0.325907383352763 0.325907383352763 0.00494180753989851 0.0148254226196955 0.198861511739873 0.298292267609809
Rhobtb1 ENSMUSG00000019944 0.940116835372231 0.940116835372231 0.483972934063864 0.940116835372231 0.658089294075101 0.940116835372231
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Rhobtb2 ENSMUSG00000022075 0.627243469059781 0.78839774175095 0.610520795499542 0.78839774175095 0.78839774175095 0.78839774175095
Hsp90ab1 ENSMUSG00000023944 0.489230375600429 0.561589170877515 0.0108355855226888 0.0325067565680664 0.561589170877515 0.561589170877515
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Lrrc41 ENSMUSG00000028703 0.809637539053825 0.809637539053825 0.271446051579861 0.407169077369791 0.22428142079344 0.407169077369791
Vhl ENSMUSG00000033933 0.302058328531167 0.543083626013479 0.429421565100425 0.543083626013479 0.543083626013479 0.543083626013479

Signaling by EGFR

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sh3gl1 ENSMUSG00000003200 0.734257170446249 0.734257170446249 0.404418970770285 0.606628456155427 0.397733389607841 0.606628456155427
Eps15l1 ENSMUSG00000006276 0.785251119050755 0.785251119050755 0.666888813786863 0.785251119050755 0.731161645452711 0.785251119050755
Aamp ENSMUSG00000006299 0.0648507198218777 0.0972760797328166 0.0184891169482384 0.0554673508447154 0.921405335653535 0.921405335653535
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Ubb ENSMUSG00000019505 0.162905061074918 0.162905061074918 0.0190892675391698 0.0572678026175094 0.0993164759361603 0.14897471390424
Sos1 ENSMUSG00000024241 0.2183954922843 0.655186476852899 0.818923291903937 0.911989113316841 0.911989113316841 0.911989113316841
Hgs ENSMUSG00000025793 0.769928454820851 0.849558140930601 0.621598722835601 0.849558140930601 0.849558140930601 0.849558140930601
Pag1 ENSMUSG00000027508 0.610076556056194 0.915114834084292 0.977955577639381 0.977955577639381 0.38380177868213 0.915114834084292
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Eps15 ENSMUSG00000028552 0.23839979523243 0.715199385697289 0.527457391543817 0.791186087315726 0.86523993911738 0.86523993911738
Ptpn12 ENSMUSG00000028771 0.227443583778813 0.567216004120449 0.378144002746966 0.567216004120449 0.782227063267484 0.782227063267484
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Gab1 ENSMUSG00000031714 0.616063477608458 0.616063477608458 0.0887893170410844 0.266367951123253 0.610523109025835 0.616063477608458
Cbl ENSMUSG00000034342 0.209615703545677 0.627239621225921 0.627239621225921 0.627239621225921 0.556270807441835 0.627239621225921
Epn1 ENSMUSG00000035203 0.486916318044524 0.489403403033323 0.162096873199981 0.486290619599942 0.489403403033323 0.489403403033323
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Grb2 ENSMUSG00000059923 0.940229266493984 0.974813822662166 0.758179155703622 0.974813822662166 0.974813822662166 0.974813822662166

VEGFR2 mediated cell proliferation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Rasa1 ENSMUSG00000021549 0.222896992458366 0.376945323539439 0.251296882359626 0.376945323539439 0.825080354293345 0.825080354293345
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991

Signaling by VEGF

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.450535059956733 0.952788409838873 0.800534289005856 0.952788409838873 0.952788409838873 0.952788409838873
Akt1 ENSMUSG00000001729 0.62442647811213 0.716475686263259 0.252967874747025 0.716475686263259 0.716475686263259 0.716475686263259
Rac1 ENSMUSG00000001847 0.641274629685672 0.707602345394383 0.194142302584674 0.582426907754021 0.707602345394383 0.707602345394383
Hspb1 ENSMUSG00000004951 0.627246277903456 0.627246277903456 0.00218659207650926 0.00655977622952778 0.504259003206777 0.627246277903456
Cdc42 ENSMUSG00000006699 0.524813374576155 0.798946344471169 0.532630896314113 0.798946344471169 0.893231562982283 0.893231562982283
Ctnnb1 ENSMUSG00000006932 0.940204394326816 0.940204394326816 0.655475627031583 0.940204394326816 0.632781253919244 0.940204394326816
Plcg1 ENSMUSG00000016933 0.250990425582538 0.621579314383926 0.599049879933935 0.621579314383926 0.621579314383926 0.621579314383926
Elmo2 ENSMUSG00000017670 0.852838926569052 0.852838926569052 0.548339874364785 0.822509811547178 0.45766345630976 0.822509811547178
Crk ENSMUSG00000017776 0.540387667639786 0.646875228856255 0.550820115825143 0.646875228856255 0.646875228856255 0.646875228856255
Fyn ENSMUSG00000019843 0.68137315062025 0.785337153492343 0.785337153492343 0.785337153492343 0.45761746144606 0.785337153492343
Hsp90aa1 ENSMUSG00000021270 0.305811375405113 0.91743412621534 0.902624867689304 0.9402273615256 0.9402273615256 0.9402273615256
Rasa1 ENSMUSG00000021549 0.222896992458366 0.376945323539439 0.251296882359626 0.376945323539439 0.825080354293345 0.825080354293345
Pdpk1 ENSMUSG00000024122 0.365383949547508 0.743199352890155 0.743199352890155 0.743199352890155 0.561559596418303 0.743199352890155
Mlst8 ENSMUSG00000024142 0.256193418926775 0.384290128390163 0.251310548095066 0.384290128390163 0.687157717437567 0.687157717437567
Src ENSMUSG00000027646 0.635611672900768 0.635611672900768 0.45284506061015 0.635611672900768 0.621609244245303 0.635611672900768
Pik3ca ENSMUSG00000027665 0.215474124243101 0.646422372729303 0.921403971143952 0.921403971143952 0.803618166180489 0.921403971143952
Prkcz ENSMUSG00000029053 0.6356648417343 0.722396368965168 0.384591307446558 0.722396368965168 0.722396368965168 0.722396368965168
Kras ENSMUSG00000030265 0.321049612249776 0.963148836749329 0.981108203402394 0.981108203402394 0.918268096911872 0.981108203402394
Cyfip1 ENSMUSG00000030447 0.940224004075028 0.940224004075028 0.855935402404653 0.940224004075028 0.313340697755647 0.940022093266941
Pik3r2 ENSMUSG00000031834 0.376032895298119 0.764297969095999 0.509531979397333 0.764297969095999 0.868348140775077 0.868348140775077
Bcar1 ENSMUSG00000031955 0.818931100976037 0.837368117627039 0.635623267800778 0.837368117627039 0.837368117627039 0.837368117627039
Pik3cb ENSMUSG00000032462 0.877673657386882 0.877673657386882 0.164470754751795 0.493412264255386 0.803608153978545 0.877673657386882
Vav3 ENSMUSG00000033721 0.296477147399068 0.741533540679539 0.494355693786359 0.741533540679539 0.788358145856681 0.788358145856681
Brk1 ENSMUSG00000033940 0.42477790696163 0.831217340366823 0.831217340366823 0.831217340366823 0.632837888769171 0.831217340366823
Elmo1 ENSMUSG00000041112 0.843557484868003 0.968520033426246 0.761177234032235 0.968520033426246 0.968520033426246 0.968520033426246
Pik3r1 ENSMUSG00000041417 0.695924185762385 0.865174451758442 0.865174451758442 0.865174451758442 0.561398626310209 0.865174451758442
Rictor ENSMUSG00000050310 0.408843295129998 0.613264942694996 0.300128989650943 0.613264942694996 0.76719275417074 0.76719275417074
Prkcb ENSMUSG00000052889 0.905679114858192 0.927661827592991 0.675391970757536 0.927661827592991 0.927661827592991 0.927661827592991
Mapk11 ENSMUSG00000053137 0.728135157758565 0.92133520765077 0.524728651635449 0.92133520765077 0.92133520765077 0.92133520765077
Mapk14 ENSMUSG00000053436 0.618668441330164 0.63535433721002 0.591203463097694 0.63535433721002 0.63535433721002 0.63535433721002
Dock1 ENSMUSG00000058325 0.840465317513002 0.840465317513002 0.395507615534301 0.840465317513002 0.83430893592035 0.840465317513002
Abi1 ENSMUSG00000058835 0.0932989213044689 0.243011617069894 0.162007744713263 0.243011617069894 0.593669720507407 0.593669720507407
Ptk2b ENSMUSG00000059456 0.865237524745001 0.927658298243105 0.927658298243105 0.927658298243105 0.806650982526346 0.927658298243105
Actg1 ENSMUSG00000062825 0.479470995908583 0.719206493862875 0.422437230176331 0.719206493862875 0.812693964295215 0.812693964295215
Nck2 ENSMUSG00000066877 0.695886060438501 0.773225423434546 0.393349353627609 0.773225423434546 0.773225423434546 0.773225423434546

HATs acetylate histones

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Brpf1 ENSMUSG00000001632 0.722353824502048 0.943366205553624 0.943366205553624 0.943366205553624 0.467307213375643 0.943366205553624
Ncoa2 ENSMUSG00000005886 0.535019416280279 0.908803437549071 0.65539085398071 0.908803437549071 0.908803437549071 0.908803437549071
Kansl3 ENSMUSG00000010453 0.433472716159515 0.650209074239273 0.399613773126658 0.650209074239273 0.843246126167187 0.843246126167187
Kansl1 ENSMUSG00000018412 0.940158621019912 0.940158621019912 0.73710508827901 0.940158621019912 0.905618365246514 0.940158621019912
Phf15 ENSMUSG00000020387 0.687207567008137 0.971664318983643 0.800565431638619 0.971664318983643 0.971664318983643 0.971664318983643
Phf17 ENSMUSG00000025764 0.569608440790859 0.993697933969124 0.754972626572436 0.993697933969124 0.993697933969124 0.993697933969124
Wdr5 ENSMUSG00000026917 0.105619541200883 0.158429311801325 0.0721208514529023 0.158429311801325 0.952765843348285 0.952765843348285
Atf2 ENSMUSG00000027104 0.583115038168057 0.678506497851335 0.678506497851335 0.678506497851335 0.585818360601496 0.678506497851335
Meaf6 ENSMUSG00000028863 0.740214769097768 0.740214769097768 0.59398460012931 0.740214769097768 0.467338993023189 0.740214769097768
Ing4 ENSMUSG00000030330 0.0672153039305514 0.201645911791654 0.618810953285995 0.618810953285995 0.462454587822382 0.618810953285995
Kat8 ENSMUSG00000030801 0.48694145843119 0.535227995840665 0.535227995840665 0.535227995840665 0.408905600063383 0.535227995840665
Rbbp7 ENSMUSG00000031353 0.707622821715022 0.707622821715022 0.336697086406689 0.560663310492342 0.373775540328228 0.560663310492342
Hcfc1 ENSMUSG00000031386 0.825039757364715 0.84353918546646 0.506966499474507 0.84353918546646 0.84353918546646 0.84353918546646
Ogt ENSMUSG00000034160 0.51971145729338 0.764181276497974 0.247988518214292 0.743965554642877 0.764181276497974 0.764181276497974
Phf16 ENSMUSG00000037315 0.198250003984015 0.594750011952045 0.731085974365816 0.788262803090994 0.788262803090994 0.788262803090994
Mcrs1 ENSMUSG00000037570 0.03229183981386 0.09687551944158 0.128079116347333 0.192118674520999 0.300221417806244 0.300221417806244
Kat7 ENSMUSG00000038909 0.678512363150713 0.678512363150713 0.438688497868846 0.658032746803269 0.328828069028127 0.658032746803269
Msl1 ENSMUSG00000052915 0.593924867895851 0.776217548211989 0.472039200468143 0.776217548211989 0.776217548211989 0.776217548211989
Hist1h2bg ENSMUSG00000058385 0.927607331042354 0.927619425125743 0.927619425125743 0.927619425125743 0.686827833190683 0.927619425125743
Hist1h4a ENSMUSG00000060093 0.135146194700564 0.405438584101692 0.671140845917975 0.839640868091949 0.839640868091949 0.839640868091949
Hist1h4k ENSMUSG00000064288 0.329713111408503 0.968400729988743 0.968400729988743 0.968400729988743 0.691723827354735 0.968400729988743
Msl2 ENSMUSG00000066415 0.924536064943825 0.971666760277029 0.561590614448763 0.971666760277029 0.971666760277029 0.971666760277029
Hist1h4j ENSMUSG00000067455 0.464635462132201 0.464635462132201 0.266112052832629 0.399168079248944 0.169207259940986 0.399168079248944
Hist2h2be ENSMUSG00000068854 0.494394081735619 0.73716646108317 0.72825381911844 0.73716646108317 0.73716646108317 0.73716646108317
Hist1h2br ENSMUSG00000069303 0.623227411477535 0.623227411477535 0.46341418833317 0.623227411477535 0.450091697570995 0.623227411477535
Hist2h3c2 ENSMUSG00000081058 0.707563250802671 0.707563250802671 0.017433580925128 0.0523007427753841 0.422496222221813 0.63374433333272
Hist2h4 ENSMUSG00000091405 0.0278921255611961 0.0836763766835882 0.210838499089379 0.316257748634069 0.918196366770502 0.918196366770502

mediumpurple3

Parathyroid hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp27b1 ENSMUSG00000006724 0.394601437454588 0.771807334085158 0.528992214796102 0.771807334085158 0.771807334085158 0.771807334085158
Gata3 ENSMUSG00000015619 0.877831242955526 0.952044088677856 0.952044088677856 0.952044088677856 0.864834734193458 0.952044088677856
Slc34a1 ENSMUSG00000021490 0.391505413791949 0.990301938465726 0.990301938465726 0.990301938465726 0.886619205721843 0.990301938465726
Mmp15 ENSMUSG00000031790 0.902565258062947 0.949623862666118 0.0500733178791777 0.150219953637533 0.949623862666118 0.949623862666118
Pde4c ENSMUSG00000031842 0.550895330409738 0.550895330409738 0.26108215494295 0.550895330409738 0.455204347405373 0.550895330409738
Pth1r ENSMUSG00000032492 0.0570819457276175 0.171245837182853 0.154987594544737 0.232481391817105 0.621565009462224 0.621565009462224
Cyp24a1 ENSMUSG00000038567 0.0564901180393707 0.169470354118112 0.356184337070766 0.534276505606149 0.873539756103201 0.873539756103201
Casr ENSMUSG00000051980 0.954847494494081 0.954847494494081 0.827478018466247 0.954847494494081 0.405493070480541 0.954847494494081

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Blvra ENSMUSG00000001999 0.644151430230936 0.955939653353301 0.955939653353301 0.955939653353301 0.952795670399274 0.955939653353301
Atp4a ENSMUSG00000005553 0.701010272555635 0.858812988227331 0.858812988227331 0.858812988227331 0.706732684618028 0.858812988227331
Cyp27b1 ENSMUSG00000006724 0.394601437454588 0.771807334085158 0.528992214796102 0.771807334085158 0.771807334085158 0.771807334085158
Odc1 ENSMUSG00000011179 0.861932014768278 0.861932014768278 0.203869364173027 0.611608092519082 0.748837002115397 0.861932014768278
Galns ENSMUSG00000015027 0.955938670531165 0.955938670531165 0.535232103433619 0.955938670531165 0.776243316328852 0.955938670531165
Gpx3 ENSMUSG00000018339 0.984255450206677 0.987405110350317 0.695918537274562 0.987405110350317 0.987405110350317 0.987405110350317
Miox ENSMUSG00000022613 0.528864954506335 0.971257196303218 0.901212881049387 0.971257196303218 0.971257196303218 0.971257196303218
Gusb ENSMUSG00000025534 0.871364392527733 0.871364392527733 0.128877903677363 0.386633711032089 0.424642164816983 0.636963247225474
Pde8a ENSMUSG00000025584 0.238313706617835 0.261226321278383 0.261226321278383 0.261226321278383 0.221389154847877 0.261226321278383
Acmsd ENSMUSG00000026348 0.759674573392706 0.937860249683321 0.775257255511039 0.937860249683321 0.937860249683321 0.937860249683321
Mccc1 ENSMUSG00000027709 0.254357479191213 0.484268572881284 0.322845715254189 0.484268572881284 0.83116271242742 0.83116271242742
Bdh2 ENSMUSG00000028167 0.698860607131644 0.94965242067768 0.94965242067768 0.94965242067768 0.577633216701746 0.94965242067768
Atp6v0d2 ENSMUSG00000028238 0.680074322698449 0.733516244994158 0.733516244994158 0.733516244994158 0.26906922879679 0.733516244994158
Cyp2j13 ENSMUSG00000028571 0.457502807694621 0.578750165472636 0.487654855986852 0.578750165472636 0.578750165472636 0.578750165472636
Alpl ENSMUSG00000028766 0.965352192202534 0.965352192202534 0.259510059962707 0.77853017988812 0.874489657103716 0.965352192202534
Acox3 ENSMUSG00000029098 0.410923242549243 0.44329313607546 0.225896804237039 0.44329313607546 0.44329313607546 0.44329313607546
Ppat ENSMUSG00000029246 0.0367023988388627 0.0757635503731198 0.0505090335820798 0.0757635503731198 0.479394191397308 0.479394191397308
Acsm2 ENSMUSG00000030945 0.680378223670482 0.936750105220964 0.407285535609282 0.936750105220964 0.936750105220964 0.936750105220964
Car5b ENSMUSG00000031373 0.558922972131056 0.779272123003434 0.604944785290192 0.779272123003434 0.779272123003434 0.779272123003434
Renbp ENSMUSG00000031387 0.952795596704831 0.952795596704831 0.203854887350361 0.611564662051083 0.722345081290214 0.952795596704831
Pde4c ENSMUSG00000031842 0.550895330409738 0.550895330409738 0.26108215494295 0.550895330409738 0.455204347405373 0.550895330409738
Galnt11 ENSMUSG00000038072 0.535200700421617 0.684255741185968 0.684255741185968 0.684255741185968 0.486920021121482 0.684255741185968
Cyp24a1 ENSMUSG00000038567 0.0564901180393707 0.169470354118112 0.356184337070766 0.534276505606149 0.873539756103201 0.873539756103201
Atp6v0a4 ENSMUSG00000038600 0.955675191140969 0.955675191140969 0.215408744056264 0.646226232168791 0.493688828844196 0.740533243266295
Gcnt1 ENSMUSG00000038843 0.952608980197449 0.952608980197449 0.859004190298121 0.952608980197449 0.565360616572579 0.952608980197449
Cox15 ENSMUSG00000040018 0.0658202717617829 0.0987304076426743 0.000858905479477249 0.00257671643843175 0.22866071996904 0.22866071996904
Dao ENSMUSG00000042096 0.570894379792707 0.886286807975862 0.886286807975862 0.886286807975862 0.753794454579481 0.886286807975862
Agps ENSMUSG00000042410 0.399952776460088 0.965368715823578 0.908874642148701 0.965368715823578 0.965368715823578 0.965368715823578
Npl ENSMUSG00000042684 0.346675660336263 0.767788282648039 0.511858855098692 0.767788282648039 0.785333738426399 0.785333738426399
A4galt ENSMUSG00000047878 0.517165087135808 0.517165087135808 0.352868530847547 0.517165087135808 0.467200925030582 0.517165087135808
Ugt2b38 ENSMUSG00000061906 0.579873558409237 0.692173020774747 0.527696499579965 0.692173020774747 0.692173020774747 0.692173020774747
Gm11128 ENSMUSG00000079495 0.784963925910435 0.784963925910435 0.7280596952492 0.784963925910435 0.704297734565155 0.784963925910435
Cyp2j8 ENSMUSG00000082932 0.0556143466122802 0.0834215199184203 0.0452699757709393 0.0834215199184203 0.437690181715734 0.437690181715734
Gm4477 ENSMUSG00000089694 0.403388723593536 0.757505030822962 0.614906232076037 0.757505030822962 0.757505030822962 0.757505030822962
Car15 ENSMUSG00000090236 0.809745900985444 0.981109200842675 0.981109200842675 0.981109200842675 0.311457392218131 0.934372176654394

Cellular response to chemical stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyba ENSMUSG00000006519 0.332559153128793 0.49883872969319 0.283443207770241 0.49883872969319 0.921341319671931 0.921341319671931
Gpx3 ENSMUSG00000018339 0.984255450206677 0.987405110350317 0.695918537274562 0.987405110350317 0.987405110350317 0.987405110350317
Prdx5 ENSMUSG00000024953 0.408897105066874 0.556253504490683 0.556253504490683 0.556253504490683 0.464908826138921 0.556253504490683
Nox4 ENSMUSG00000030562 0.511742175218538 0.67807545479393 0.67807545479393 0.67807545479393 0.649179742201215 0.67807545479393
Sod3 ENSMUSG00000072941 0.476577181586665 0.476577181586665 0.0738384824748687 0.221515447424606 0.427104226455756 0.476577181586665

Detoxification of Reactive Oxygen Species

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyba ENSMUSG00000006519 0.332559153128793 0.49883872969319 0.283443207770241 0.49883872969319 0.921341319671931 0.921341319671931
Gpx3 ENSMUSG00000018339 0.984255450206677 0.987405110350317 0.695918537274562 0.987405110350317 0.987405110350317 0.987405110350317
Prdx5 ENSMUSG00000024953 0.408897105066874 0.556253504490683 0.556253504490683 0.556253504490683 0.464908826138921 0.556253504490683
Nox4 ENSMUSG00000030562 0.511742175218538 0.67807545479393 0.67807545479393 0.67807545479393 0.649179742201215 0.67807545479393
Sod3 ENSMUSG00000072941 0.476577181586665 0.476577181586665 0.0738384824748687 0.221515447424606 0.427104226455756 0.476577181586665

midnightblue

Protein processing in endoplasmic reticulum

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ssr4 ENSMUSG00000002014 0.77323843043891 0.77323843043891 0.618848349511295 0.77323843043891 0.698831616236058 0.77323843043891
Bcap31 ENSMUSG00000002015 0.758163089367248 0.849745868497015 0.849745868497015 0.849745868497015 0.535248350186248 0.849745868497015
Man1a ENSMUSG00000003746 0.779286627504559 0.98740515112606 0.77928192105922 0.98740515112606 0.98740515112606 0.98740515112606
Dnajb11 ENSMUSG00000004460 0.550924060666451 0.550924060666451 0.17554476615973 0.52663429847919 0.491741704926768 0.550924060666451
Dnajb12 ENSMUSG00000020109 0.930719486434075 0.930719486434075 0.580399343498067 0.870599015247101 0.45706013046938 0.870599015247101
Rnf185 ENSMUSG00000020448 0.959062662234511 0.959062662234511 0.328802707541772 0.923904743597005 0.615936495731336 0.923904743597005
Xbp1 ENSMUSG00000020484 0.949641993055717 0.949641993055717 0.350906368438782 0.949641993055717 0.809690012176279 0.949641993055717
Ern1 ENSMUSG00000020715 0.698852960235115 0.949648490724686 0.514556986247866 0.949648490724686 0.949648490724686 0.949648490724686
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Dnajc3 ENSMUSG00000022136 0.1470635192484 0.441190557745199 0.519727891237304 0.779591836855956 0.905752548968555 0.905752548968555
Dad1 ENSMUSG00000022174 0.722324409531045 0.722324409531045 0.556089733095029 0.722324409531045 0.328726986231542 0.722324409531045
Derl1 ENSMUSG00000022365 0.977960617563032 0.977960617563032 0.365269222587825 0.749007748835023 0.499338499223348 0.749007748835023
Park2 ENSMUSG00000023826 0.773222171333825 0.773222171333825 0.292805597347077 0.773222171333825 0.713513242288389 0.773222171333825
Pdia4 ENSMUSG00000025823 0.309326410911575 0.927979232734725 0.962205501940277 0.962205501940277 0.927675875408037 0.962205501940277
Tram1 ENSMUSG00000025935 0.39993731938157 0.883881028294624 0.883881028294624 0.883881028294624 0.791429635396548 0.883881028294624
Dnajc1 ENSMUSG00000026740 0.0345668776920135 0.103700633076041 0.206383792571413 0.30957568885712 0.722102708885743 0.722102708885743
Rrbp1 ENSMUSG00000027422 0.71350167725594 0.806688062784182 0.806688062784182 0.806688062784182 0.767175782847789 0.806688062784182
Edem1 ENSMUSG00000030104 0.362908040740202 0.862276684493548 0.896296200003962 0.896296200003962 0.574851122995699 0.862276684493548
Cryab ENSMUSG00000032060 0.834308006023964 0.946510647645725 0.294707319770529 0.884121959311588 0.946510647645725 0.946510647645725
Stt3a ENSMUSG00000032116 0.138404847263382 0.415214541790145 0.301960559414469 0.452940839121703 0.641256923969734 0.641256923969734
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Ssr2 ENSMUSG00000041355 0.61881467772081 0.649777433207397 0.29833549041971 0.649777433207397 0.649777433207397 0.649777433207397
Edem3 ENSMUSG00000043019 0.039395007369935 0.118185022109805 0.275035488005308 0.412553232007961 0.764164176069748 0.764164176069748
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Ubxn8 ENSMUSG00000052906 0.81264957715932 0.880706451052495 0.880706451052495 0.880706451052495 0.512007738999251 0.880706451052495
Sec61b ENSMUSG00000053317 0.326852872736643 0.775741305457583 0.517160870305055 0.775741305457583 0.937088328516385 0.937088328516385
Vimp ENSMUSG00000075701 0.97795454855816 0.97795454855816 0.695894907048106 0.97795454855816 0.499436288632329 0.97795454855816

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlat ENSMUSG00000000168 0.503570854526072 0.632102801487263 0.0586095571332327 0.175828671399698 0.632102801487263 0.632102801487263
Gmpr ENSMUSG00000000253 0.399978623586033 0.59996793537905 0.173169604896188 0.519508814688563 0.893258653663041 0.893258653663041
Acp5 ENSMUSG00000001348 0.993699729886046 0.993699729886046 0.570778064868416 0.993699729886046 0.899130931226438 0.993699729886046
Naglu ENSMUSG00000001751 0.102276109935138 0.306828329805416 0.27845931592216 0.41768897388324 0.825041584064722 0.825041584064722
Man1a ENSMUSG00000003746 0.779286627504559 0.98740515112606 0.77928192105922 0.98740515112606 0.98740515112606 0.98740515112606
Elovl1 ENSMUSG00000006390 0.874517531499764 0.874517531499764 0.540302988965073 0.810454483447609 0.530020246503933 0.810454483447609
Mvd ENSMUSG00000006517 0.767192198620693 0.767192198620693 0.157355129810763 0.472065389432289 0.530029814345161 0.767192198620693
Atp6v0e ENSMUSG00000015575 0.499417003944229 0.519634774576191 0.519634774576191 0.519634774576191 0.499336963314266 0.519634774576191
Acot8 ENSMUSG00000017307 0.72827289083604 0.72827289083604 0.664052844072961 0.72827289083604 0.285601269668361 0.72827289083604
Afmid ENSMUSG00000017718 0.338717423805834 0.50807613570875 0.178229825801635 0.50807613570875 0.965371509968845 0.965371509968845
B4galt5 ENSMUSG00000017929 0.514571378080404 0.877660077205933 0.877660077205933 0.877660077205933 0.70759985178933 0.877660077205933
Pank3 ENSMUSG00000018846 0.281752260876164 0.830148536824887 0.553432357883258 0.830148536824887 0.855927255547223 0.855927255547223
P4ha2 ENSMUSG00000018906 0.75516453053895 0.946499744401815 0.176793352141806 0.530380056425419 0.946499744401815 0.946499744401815
Sgpl1 ENSMUSG00000020097 0.410010139296769 0.865183077505041 0.784772702761252 0.865183077505041 0.865183077505041 0.865183077505041
Gfpt2 ENSMUSG00000020363 0.98737533851357 0.98737533851357 0.955787648567063 0.98737533851357 0.788106507293002 0.98737533851357
Nt5c ENSMUSG00000020736 0.803599085813525 0.899486861523263 0.899486861523263 0.899486861523263 0.868339881569116 0.899486861523263
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Mthfd1 ENSMUSG00000021048 0.601687599101695 0.601687599101695 0.271468633051307 0.601687599101695 0.582584269629009 0.601687599101695
Sgpp1 ENSMUSG00000021054 0.484473238419926 0.716438618279956 0.701747400817793 0.716438618279956 0.716438618279956 0.716438618279956
Gcnt2 ENSMUSG00000021360 0.76418804918208 0.974814100939388 0.974814100939388 0.974814100939388 0.672719353082425 0.974814100939388
Sptlc1 ENSMUSG00000021468 0.749112639819611 0.965368862697293 0.965368862697293 0.965368862697293 0.604949386196136 0.965368862697293
Pcbd2 ENSMUSG00000021496 0.218361835928509 0.327542753892764 0.0152858911656433 0.0458576734969298 0.65262844983756 0.65262844983756
Dhfr ENSMUSG00000021707 0.905716770880661 0.955939348685473 0.955939348685473 0.955939348685473 0.834252731128751 0.955939348685473
Tgds ENSMUSG00000022130 0.271562272059165 0.773237617566686 0.599491006022079 0.773237617566686 0.773237617566686 0.773237617566686
Dad1 ENSMUSG00000022174 0.722324409531045 0.722324409531045 0.556089733095029 0.722324409531045 0.328726986231542 0.722324409531045
Naga ENSMUSG00000022453 0.191435147316482 0.431149357123048 0.287432904748699 0.431149357123048 0.48943546206012 0.48943546206012
Pigx ENSMUSG00000023791 0.990553820628636 0.990553820628636 0.91827208901833 0.990553820628636 0.713530189569765 0.990553820628636
Man2a1 ENSMUSG00000024085 0.195523414879639 0.586570244638918 0.86833470967 0.924534855152377 0.924534855152377 0.924534855152377
Pigf ENSMUSG00000024145 0.773041040312909 0.962204007443159 0.962204007443159 0.962204007443159 0.949643290544104 0.962204007443159
Acsl5 ENSMUSG00000024981 0.828128391170635 0.828128391170635 0.695908595172244 0.828128391170635 0.607744718414025 0.828128391170635
Got1 ENSMUSG00000025190 0.782278986854115 0.782278986854115 0.127864751830479 0.383594255491437 0.433782656373795 0.650673984560693
Sacm1l ENSMUSG00000025240 0.0918401354358094 0.275520406307428 0.616062570758635 0.698853312197103 0.698853312197103 0.698853312197103
Shmt2 ENSMUSG00000025403 0.511697778241247 0.767546667361871 0.137201349124548 0.411604047373643 0.937038629669983 0.937038629669983
Tk1 ENSMUSG00000025574 0.962174249500486 0.962174249500486 0.534776003057047 0.80216400458557 0.532314383313339 0.80216400458557
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Rdh10 ENSMUSG00000025921 0.806617757263259 0.984254513163533 0.438668004095544 0.984254513163533 0.984254513163533 0.984254513163533
Rpe ENSMUSG00000026005 0.340654752603631 0.996850750704082 0.782280788924819 0.996850750704082 0.996850750704082 0.996850750704082
Scly ENSMUSG00000026307 0.566558936023476 0.840349869795679 0.491873795377542 0.840349869795679 0.840349869795679 0.840349869795679
Smyd2 ENSMUSG00000026603 0.519697122914262 0.779545684371392 0.452888137437023 0.779545684371392 0.868340129222234 0.868340129222234
Sephs1 ENSMUSG00000026662 0.770214905229503 0.770214905229503 0.716432524768344 0.770214905229503 0.675560723602626 0.770214905229503
Ak1 ENSMUSG00000026817 0.610369729061708 0.843475924621706 0.658308565535219 0.843475924621706 0.843475924621706 0.843475924621706
Uap1l1 ENSMUSG00000026956 0.166949833270953 0.287174419222039 0.191449612814693 0.287174419222039 0.96852002288803 0.96852002288803
Dhrs9 ENSMUSG00000027068 0.243752118116576 0.729552308658135 0.48636820577209 0.729552308658135 0.772287355189387 0.772287355189387
Chac1 ENSMUSG00000027313 0.902583883612485 0.97164355198828 0.420076774600191 0.97164355198828 0.97164355198828 0.97164355198828
Gclm ENSMUSG00000028124 0.386679585373224 0.586625824157339 0.39108388277156 0.586625824157339 0.955920338679395 0.955920338679395
Alad ENSMUSG00000028393 0.0617687175798906 0.0926530763698359 0.00151445837037118 0.00454337511111355 0.638111751775025 0.638111751775025
Ppcs ENSMUSG00000028636 0.303939401170929 0.455909101756394 0.111847346049347 0.335542038148041 0.591203546049003 0.591203546049003
Cmpk1 ENSMUSG00000028719 0.0491551050529873 0.147465315158962 0.228842089369934 0.3432631340549 0.371759912518883 0.371759912518883
Ak2 ENSMUSG00000028792 0.133901271809995 0.200851907714992 0.108248754101694 0.200851907714992 0.785163902554725 0.785163902554725
Mecr ENSMUSG00000028910 0.157249082739605 0.235873624109407 0.0665604409689729 0.199681322906919 0.427117417047903 0.427117417047903
Pgd ENSMUSG00000028961 0.78535887978727 0.78535887978727 0.266381973037224 0.78535887978727 0.602208354073547 0.78535887978727
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Rbks ENSMUSG00000029136 0.655506775251554 0.86524266630788 0.406643838104991 0.86524266630788 0.86524266630788 0.86524266630788
Sepsecs ENSMUSG00000029173 0.849747211262744 0.868349844862227 0.868349844862227 0.868349844862227 0.843567589042913 0.868349844862227
Pi4k2b ENSMUSG00000029186 0.974801453908087 0.974801453908087 0.678470451430415 0.974801453908087 0.469598984596345 0.974801453908087
Akr1b8 ENSMUSG00000029762 0.959080171784373 0.959080171784373 0.477085523196963 0.838361782298142 0.558907854865428 0.838361782298142
Dera ENSMUSG00000030225 0.968520644624679 0.968520644624679 0.874561002945649 0.968520644624679 0.943367606951117 0.968520644624679
Pik3c2a ENSMUSG00000030660 0.0544897676496011 0.124310815602287 0.0828738770681911 0.124310815602287 0.868347601861949 0.868347601861949
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Piga ENSMUSG00000031381 0.355017601035944 0.693722589269888 0.933950234088727 0.933950234088727 0.462481726179925 0.693722589269888
Gsr ENSMUSG00000031584 0.646932834355793 0.76415208338811 0.743161076756038 0.76415208338811 0.76415208338811 0.76415208338811
Pgls ENSMUSG00000031807 0.367444654769433 0.640306024465269 0.426870682976846 0.640306024465269 0.930795478096443 0.930795478096443
Pts ENSMUSG00000032067 0.984251336872471 0.984251336872471 0.915120087230139 0.984251336872471 0.886981863969416 0.984251336872471
Stt3a ENSMUSG00000032116 0.138404847263382 0.415214541790145 0.301960559414469 0.452940839121703 0.641256923969734 0.641256923969734
Dpagt1 ENSMUSG00000032123 0.522315988902916 0.522315988902916 0.13628789903669 0.396998496635402 0.264665664423602 0.396998496635402
Pfkm ENSMUSG00000033065 0.375894813643832 0.563842220465748 0.177804478455957 0.533413435367871 0.731099043606285 0.731099043606285
Tmem5 ENSMUSG00000034620 0.422515484281347 0.63377322642202 0.0767276108644568 0.23018283259337 0.65833173893646 0.65833173893646
Alg5 ENSMUSG00000036632 0.846647634880647 0.959082682399838 0.474609558693488 0.959082682399838 0.959082682399838 0.959082682399838
Amdhd2 ENSMUSG00000036820 0.102313712342405 0.306941137027215 0.359164407298384 0.538746610947576 0.76721042868766 0.76721042868766
Smpd1 ENSMUSG00000037049 0.646943756363319 0.728266417400137 0.191327285320162 0.573981855960487 0.728266417400137 0.728266417400137
Enpp1 ENSMUSG00000037370 0.382351301683826 0.693594888455176 0.943362682662659 0.943362682662659 0.462396592303451 0.693594888455176
Kmo ENSMUSG00000039783 0.525869360757365 0.788804041136048 0.370962318545351 0.788804041136048 0.806355122990017 0.806355122990017
C1galt1 ENSMUSG00000042460 0.252523135042761 0.378784702564141 0.152394911093299 0.378784702564141 0.766989688593159 0.766989688593159
Dpm3 ENSMUSG00000042737 0.0530141839050926 0.159042551715278 0.303723784691225 0.455585677036838 0.462358669867307 0.462358669867307
Mgat2 ENSMUSG00000043998 0.479500636817308 0.933946878912088 0.740209986526565 0.933946878912088 0.933946878912088 0.933946878912088
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542
C1galt1c1 ENSMUSG00000048970 0.268036420378607 0.690085470108433 0.460056980072288 0.690085470108433 0.977961116937497 0.977961116937497
Idnk ENSMUSG00000050002 0.262716176787108 0.394074265180661 0.20942566750374 0.394074265180661 0.566943751856273 0.566943751856273
Nat2 ENSMUSG00000051147 0.83429746610403 0.899489753459833 0.821987601659315 0.899489753459833 0.899489753459833 0.899489753459833
Gnpda1 ENSMUSG00000052102 0.852842597710133 0.908882654894043 0.484478026561191 0.908882654894043 0.908882654894043 0.908882654894043
Nt5c1a ENSMUSG00000054958 0.987309934228535 0.987309934228535 0.37204385110793 0.987309934228535 0.930342343122478 0.987309934228535
Acyp2 ENSMUSG00000060923 0.815858453877098 0.840468709760936 0.794473718492208 0.840468709760936 0.840468709760936 0.840468709760936
Gpx1 ENSMUSG00000063856 0.574805433974788 0.582906160158444 0.395544061878369 0.582906160158444 0.582906160158444 0.582906160158444
Gmppb ENSMUSG00000070284 0.514539253389735 0.771808880084603 0.420088016716951 0.771808880084603 0.852812782050637 0.852812782050637
Gm10639 ENSMUSG00000074179 0.760196408233127 0.996755625274193 0.996755625274193 0.996755625274193 0.741565637093063 0.996755625274193
Gm2382 ENSMUSG00000079427 0.550976963452875 0.927674087665971 0.855933843152167 0.927674087665971 0.927674087665971 0.927674087665971

Biosynthesis of cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Afmid ENSMUSG00000017718 0.338717423805834 0.50807613570875 0.178229825801635 0.50807613570875 0.965371509968845 0.965371509968845
Pank3 ENSMUSG00000018846 0.281752260876164 0.830148536824887 0.553432357883258 0.830148536824887 0.855927255547223 0.855927255547223
Mthfd1 ENSMUSG00000021048 0.601687599101695 0.601687599101695 0.271468633051307 0.601687599101695 0.582584269629009 0.601687599101695
Dhfr ENSMUSG00000021707 0.905716770880661 0.955939348685473 0.955939348685473 0.955939348685473 0.834252731128751 0.955939348685473
Shmt2 ENSMUSG00000025403 0.511697778241247 0.767546667361871 0.137201349124548 0.411604047373643 0.937038629669983 0.937038629669983
Ak1 ENSMUSG00000026817 0.610369729061708 0.843475924621706 0.658308565535219 0.843475924621706 0.843475924621706 0.843475924621706
Gclm ENSMUSG00000028124 0.386679585373224 0.586625824157339 0.39108388277156 0.586625824157339 0.955920338679395 0.955920338679395
Alad ENSMUSG00000028393 0.0617687175798906 0.0926530763698359 0.00151445837037118 0.00454337511111355 0.638111751775025 0.638111751775025
Ppcs ENSMUSG00000028636 0.303939401170929 0.455909101756394 0.111847346049347 0.335542038148041 0.591203546049003 0.591203546049003
Cmpk1 ENSMUSG00000028719 0.0491551050529873 0.147465315158962 0.228842089369934 0.3432631340549 0.371759912518883 0.371759912518883
Ak2 ENSMUSG00000028792 0.133901271809995 0.200851907714992 0.108248754101694 0.200851907714992 0.785163902554725 0.785163902554725
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Pts ENSMUSG00000032067 0.984251336872471 0.984251336872471 0.915120087230139 0.984251336872471 0.886981863969416 0.984251336872471
Kmo ENSMUSG00000039783 0.525869360757365 0.788804041136048 0.370962318545351 0.788804041136048 0.806355122990017 0.806355122990017
Gmppb ENSMUSG00000070284 0.514539253389735 0.771808880084603 0.420088016716951 0.771808880084603 0.852812782050637 0.852812782050637

Apoptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.593940298488105 0.890099435224894 0.229049055339806 0.687147166019417 0.890099435224894 0.890099435224894
Ikbkg ENSMUSG00000004221 0.029774850671308 0.0644918716991508 0.0429945811327672 0.0644918716991508 0.649814571362946 0.649814571362946
Bid ENSMUSG00000004446 0.949645211316795 0.949645211316795 0.684240685913697 0.949645211316795 0.62722365144531 0.949645211316795
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Ern1 ENSMUSG00000020715 0.698852960235115 0.949648490724686 0.514556986247866 0.949648490724686 0.949648490724686 0.949648490724686
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Casp6 ENSMUSG00000027997 0.527384243425511 0.613122398755503 0.529856215086628 0.613122398755503 0.613122398755503 0.613122398755503
Itpr2 ENSMUSG00000030287 0.632761140357658 0.632761140357658 0.457632207224365 0.632761140357658 0.501910077658152 0.632761140357658
Tnfrsf1a ENSMUSG00000030341 0.971664717476175 0.971664717476175 0.208152371092993 0.624457113278978 0.855926077957422 0.971664717476175
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945
Casp3 ENSMUSG00000031628 0.680957908352159 0.755079751916183 0.555860247383489 0.755079751916183 0.755079751916183 0.755079751916183

Pentose phosphate pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpe ENSMUSG00000026005 0.340654752603631 0.996850750704082 0.782280788924819 0.996850750704082 0.996850750704082 0.996850750704082
Pgd ENSMUSG00000028961 0.78535887978727 0.78535887978727 0.266381973037224 0.78535887978727 0.602208354073547 0.78535887978727
Rbks ENSMUSG00000029136 0.655506775251554 0.86524266630788 0.406643838104991 0.86524266630788 0.86524266630788 0.86524266630788
Dera ENSMUSG00000030225 0.968520644624679 0.968520644624679 0.874561002945649 0.968520644624679 0.943367606951117 0.968520644624679
Pgls ENSMUSG00000031807 0.367444654769433 0.640306024465269 0.426870682976846 0.640306024465269 0.930795478096443 0.930795478096443
Pfkm ENSMUSG00000033065 0.375894813643832 0.563842220465748 0.177804478455957 0.533413435367871 0.731099043606285 0.731099043606285
Idnk ENSMUSG00000050002 0.262716176787108 0.394074265180661 0.20942566750374 0.394074265180661 0.566943751856273 0.566943751856273

N-Glycan biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Man1a ENSMUSG00000003746 0.779286627504559 0.98740515112606 0.77928192105922 0.98740515112606 0.98740515112606 0.98740515112606
Dad1 ENSMUSG00000022174 0.722324409531045 0.722324409531045 0.556089733095029 0.722324409531045 0.328726986231542 0.722324409531045
Man2a1 ENSMUSG00000024085 0.195523414879639 0.586570244638918 0.86833470967 0.924534855152377 0.924534855152377 0.924534855152377
Stt3a ENSMUSG00000032116 0.138404847263382 0.415214541790145 0.301960559414469 0.452940839121703 0.641256923969734 0.641256923969734
Dpagt1 ENSMUSG00000032123 0.522315988902916 0.522315988902916 0.13628789903669 0.396998496635402 0.264665664423602 0.396998496635402
Alg5 ENSMUSG00000036632 0.846647634880647 0.959082682399838 0.474609558693488 0.959082682399838 0.959082682399838 0.959082682399838
Dpm3 ENSMUSG00000042737 0.0530141839050926 0.159042551715278 0.303723784691225 0.455585677036838 0.462358669867307 0.462358669867307
Mgat2 ENSMUSG00000043998 0.479500636817308 0.933946878912088 0.740209986526565 0.933946878912088 0.933946878912088 0.933946878912088

Ferroptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lpcat3 ENSMUSG00000004270 0.666830152414596 0.666830152414596 0.494350188390407 0.666830152414596 0.643982287880309 0.666830152414596
Acsl5 ENSMUSG00000024981 0.828128391170635 0.828128391170635 0.695908595172244 0.828128391170635 0.607744718414025 0.828128391170635
Gclm ENSMUSG00000028124 0.386679585373224 0.586625824157339 0.39108388277156 0.586625824157339 0.955920338679395 0.955920338679395
Atg5 ENSMUSG00000038160 0.524757871519557 0.932299270073262 0.621532846715508 0.932299270073262 0.933945789841338 0.933945789841338
Ftl1 ENSMUSG00000050708 0.612936579052181 0.779045322996064 0.201000703007295 0.603002109021885 0.779045322996064 0.779045322996064
Slc39a8 ENSMUSG00000053897 0.785327796758932 0.871439336632888 0.871439336632888 0.871439336632888 0.782321323692487 0.871439336632888
Ncoa4 ENSMUSG00000056234 0.128072675015661 0.384218025046983 0.49438708080464 0.519745910628397 0.519745910628397 0.519745910628397

Necroptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stat6 ENSMUSG00000002147 0.952792506491467 0.952792506491467 0.462460446445136 0.952792506491467 0.638495324778706 0.952792506491467
Bid ENSMUSG00000004446 0.949645211316795 0.949645211316795 0.684240685913697 0.949645211316795 0.62722365144531 0.949645211316795
Vps4b ENSMUSG00000009907 0.386634745687049 0.664082478537564 0.664082478537564 0.664082478537564 0.550804069940743 0.664082478537564
Mlkl ENSMUSG00000012519 0.952785792267244 0.952785792267244 0.908859482047486 0.952785792267244 0.408758355373737 0.952785792267244
Slc25a5 ENSMUSG00000016319 0.758161362176382 0.758161362176382 0.443321971754066 0.711941913570843 0.474627942380562 0.711941913570843
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Chmp5 ENSMUSG00000028419 0.89010657221099 0.89010657221099 0.770174762238754 0.89010657221099 0.797498314206206 0.89010657221099
Tnfrsf1a ENSMUSG00000030341 0.971664717476175 0.971664717476175 0.208152371092993 0.624457113278978 0.855926077957422 0.971664717476175
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945
Smpd1 ENSMUSG00000037049 0.646943756363319 0.728266417400137 0.191327285320162 0.573981855960487 0.728266417400137 0.728266417400137
Ftl1 ENSMUSG00000050708 0.612936579052181 0.779045322996064 0.201000703007295 0.603002109021885 0.779045322996064 0.779045322996064
Chmp3 ENSMUSG00000053119 0.481765193301798 0.722647789952697 0.27662564227443 0.722647789952697 0.806534417638617 0.806534417638617
H2afj ENSMUSG00000060032 0.300090079458121 0.450135119187181 0.0766877615232087 0.230063284569626 0.99370096993282 0.99370096993282

Lysosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acp5 ENSMUSG00000001348 0.993699729886046 0.993699729886046 0.570778064868416 0.993699729886046 0.899130931226438 0.993699729886046
Naglu ENSMUSG00000001751 0.102276109935138 0.306828329805416 0.27845931592216 0.41768897388324 0.825041584064722 0.825041584064722
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Cd164 ENSMUSG00000019818 0.359177052120861 0.840480132838849 0.840480132838849 0.840480132838849 0.818939107703279 0.840480132838849
Cln5 ENSMUSG00000022125 0.431612935332232 0.450407091685575 0.348817744577264 0.450407091685575 0.450407091685575 0.450407091685575
Naga ENSMUSG00000022453 0.191435147316482 0.431149357123048 0.287432904748699 0.431149357123048 0.48943546206012 0.48943546206012
Litaf ENSMUSG00000022500 0.0850889265889566 0.25526677976687 0.825062250631775 0.825062250631775 0.621644971537644 0.825062250631775
Lipa ENSMUSG00000024781 0.616065054723328 0.678450812396531 0.218402212777944 0.655206638333831 0.678450812396531 0.678450812396531
Fuca1 ENSMUSG00000028673 0.50442441281402 0.681404132696463 0.477005083446462 0.681404132696463 0.681404132696463 0.681404132696463
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Smpd1 ENSMUSG00000037049 0.646943756363319 0.728266417400137 0.191327285320162 0.573981855960487 0.728266417400137 0.728266417400137
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542

TNF signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.593940298488105 0.890099435224894 0.229049055339806 0.687147166019417 0.890099435224894 0.890099435224894
Ikbkg ENSMUSG00000004221 0.029774850671308 0.0644918716991508 0.0429945811327672 0.0644918716991508 0.649814571362946 0.649814571362946
Mlkl ENSMUSG00000012519 0.952785792267244 0.952785792267244 0.908859482047486 0.952785792267244 0.408758355373737 0.952785792267244
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Itch ENSMUSG00000027598 0.285650798809223 0.85695239642767 0.896368382453483 0.896368382453483 0.591256914789144 0.886885372183716
Tnfrsf1a ENSMUSG00000030341 0.971664717476175 0.971664717476175 0.208152371092993 0.624457113278978 0.855926077957422 0.971664717476175
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945
Casp3 ENSMUSG00000031628 0.680957908352159 0.755079751916183 0.555860247383489 0.755079751916183 0.755079751916183 0.755079751916183
Bcl3 ENSMUSG00000053175 0.67539967506122 0.67539967506122 0.397614918577326 0.67539967506122 0.669560162011179 0.67539967506122

Asparagine N-linked glycosylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nudt14 ENSMUSG00000002804 0.296482291573231 0.444723437359846 0.156087186687089 0.444723437359846 0.604942605857777 0.604942605857777
Man1a ENSMUSG00000003746 0.779286627504559 0.98740515112606 0.77928192105922 0.98740515112606 0.98740515112606 0.98740515112606
Mvd ENSMUSG00000006517 0.767192198620693 0.767192198620693 0.157355129810763 0.472065389432289 0.530029814345161 0.767192198620693
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
B4galt5 ENSMUSG00000017929 0.514571378080404 0.877660077205933 0.877660077205933 0.877660077205933 0.70759985178933 0.877660077205933
Gfpt2 ENSMUSG00000020363 0.98737533851357 0.98737533851357 0.955787648567063 0.98737533851357 0.788106507293002 0.98737533851357
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Derl1 ENSMUSG00000022365 0.977960617563032 0.977960617563032 0.365269222587825 0.749007748835023 0.499338499223348 0.749007748835023
Man2a1 ENSMUSG00000024085 0.195523414879639 0.586570244638918 0.86833470967 0.924534855152377 0.924534855152377 0.924534855152377
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Fuca1 ENSMUSG00000028673 0.50442441281402 0.681404132696463 0.477005083446462 0.681404132696463 0.681404132696463 0.681404132696463
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
Arcn1 ENSMUSG00000032096 0.00893972140919316 0.0268191642275795 0.0903075846117496 0.135461376917624 0.933910122459056 0.933910122459056
Dpagt1 ENSMUSG00000032123 0.522315988902916 0.522315988902916 0.13628789903669 0.396998496635402 0.264665664423602 0.396998496635402
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Alg5 ENSMUSG00000036632 0.846647634880647 0.959082682399838 0.474609558693488 0.959082682399838 0.959082682399838 0.959082682399838
Amdhd2 ENSMUSG00000036820 0.102313712342405 0.306941137027215 0.359164407298384 0.538746610947576 0.76721042868766 0.76721042868766
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Dpm3 ENSMUSG00000042737 0.0530141839050926 0.159042551715278 0.303723784691225 0.455585677036838 0.462358669867307 0.462358669867307
Mgat2 ENSMUSG00000043998 0.479500636817308 0.933946878912088 0.740209986526565 0.933946878912088 0.933946878912088 0.933946878912088
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542
Kdelr2 ENSMUSG00000079111 0.698869373150633 0.698869373150633 0.141618798356754 0.424856395070263 0.561602556176126 0.698869373150633

Purine catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nt5c ENSMUSG00000020736 0.803599085813525 0.899486861523263 0.899486861523263 0.899486861523263 0.868339881569116 0.899486861523263
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Nudt1 ENSMUSG00000036639 0.116491994026043 0.27714379501001 0.184762530006674 0.27714379501001 0.99685111991703 0.99685111991703
Nt5c1a ENSMUSG00000054958 0.987309934228535 0.987309934228535 0.37204385110793 0.987309934228535 0.930342343122478 0.987309934228535
Gpx1 ENSMUSG00000063856 0.574805433974788 0.582906160158444 0.395544061878369 0.582906160158444 0.582906160158444 0.582906160158444

Membrane Trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpd52l1 ENSMUSG00000000296 0.968516108965298 0.968516108965298 0.955932929536001 0.968516108965298 0.84354568843975 0.968516108965298
Snx9 ENSMUSG00000002365 0.933947916422629 0.933947916422629 0.309547192508182 0.928641577524545 0.782326845098921 0.933947916422629
Rab8a ENSMUSG00000003037 0.482007272489392 0.80361477165696 0.638452186186988 0.80361477165696 0.80361477165696 0.80361477165696
Akt2 ENSMUSG00000004056 0.593940298488105 0.890099435224894 0.229049055339806 0.687147166019417 0.890099435224894 0.890099435224894
Rab11a ENSMUSG00000004771 0.496786438140763 0.981108081083831 0.981108081083831 0.981108081083831 0.930797058758742 0.981108081083831
Vps4b ENSMUSG00000009907 0.386634745687049 0.664082478537564 0.664082478537564 0.664082478537564 0.550804069940743 0.664082478537564
Surf4 ENSMUSG00000014867 0.837357083130926 0.837357083130926 0.153901599572923 0.46170479871877 0.535164953549068 0.802747430323602
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Gabarap ENSMUSG00000018567 0.785347023520285 0.785347023520285 0.782303548072425 0.785347023520285 0.566910245259418 0.785347023520285
Rab5c ENSMUSG00000019173 0.971649645288956 0.971649645288956 0.713499994396498 0.971649645288956 0.629924096984163 0.971649645288956
Vps54 ENSMUSG00000020128 0.981108886655488 0.981108886655488 0.734261197137909 0.981108886655488 0.927676551816412 0.981108886655488
Tbc1d15 ENSMUSG00000020130 0.767196264145037 0.767196264145037 0.472202030901251 0.767196264145037 0.649821690901183 0.767196264145037
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Gdi2 ENSMUSG00000021218 0.902627377446034 0.905752580390091 0.859035880615437 0.905752580390091 0.905752580390091 0.905752580390091
Tbc1d7 ENSMUSG00000021368 0.042156178718098 0.063234268077147 0.0371569220325569 0.063234268077147 0.289198132046142 0.289198132046142
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Pacsin3 ENSMUSG00000027257 0.426600143959408 0.865139618544541 0.809703316551923 0.865139618544541 0.865139618544541 0.865139618544541
Tpd52 ENSMUSG00000027506 0.395534540955089 0.977960883244313 0.977960883244313 0.977960883244313 0.693015183470643 0.977960883244313
Chmp5 ENSMUSG00000028419 0.89010657221099 0.89010657221099 0.770174762238754 0.89010657221099 0.797498314206206 0.89010657221099
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
St5 ENSMUSG00000031024 0.678372593723222 0.678372593723222 0.050973784837344 0.152921354512032 0.548195203495481 0.678372593723222
Mvb12a ENSMUSG00000031813 0.342741770636901 0.365319664706036 0.31520447470145 0.365319664706036 0.365319664706036 0.365319664706036
Arcn1 ENSMUSG00000032096 0.00893972140919316 0.0268191642275795 0.0903075846117496 0.135461376917624 0.933910122459056 0.933910122459056
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Picalm ENSMUSG00000039361 0.0397914452029993 0.119374335608998 0.871434084417354 0.871434084417354 0.455265992600798 0.682898988901197
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Tbc1d13 ENSMUSG00000039678 0.837357566832851 0.837357566832851 0.761179897794168 0.837357566832851 0.618742521930405 0.837357566832851
Fcho2 ENSMUSG00000041685 0.348879664308865 0.686535183026556 0.880788811349441 0.880788811349441 0.457690122017704 0.686535183026556
Tbc1d8b ENSMUSG00000042473 0.149345226402698 0.448035679208095 0.386797144561621 0.477071330608438 0.477071330608438 0.477071330608438
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Chmp3 ENSMUSG00000053119 0.481765193301798 0.722647789952697 0.27662564227443 0.722647789952697 0.806534417638617 0.806534417638617
Stam2 ENSMUSG00000055371 0.129943786508122 0.389831359524367 0.369389228601134 0.554083842901701 0.752033452098773 0.752033452098773
Kdelr2 ENSMUSG00000079111 0.698869373150633 0.698869373150633 0.141618798356754 0.424856395070263 0.561602556176126 0.698869373150633

Caspase activation via extrinsic apoptotic signalling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Ly96 ENSMUSG00000025779 0.890135094068266 0.890135094068266 0.641318305023277 0.890135094068266 0.669844855533036 0.890135094068266
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945
Casp3 ENSMUSG00000031628 0.680957908352159 0.755079751916183 0.555860247383489 0.755079751916183 0.755079751916183 0.755079751916183

Metabolism of nucleotides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gmpr ENSMUSG00000000253 0.399978623586033 0.59996793537905 0.173169604896188 0.519508814688563 0.893258653663041 0.893258653663041
Nt5c ENSMUSG00000020736 0.803599085813525 0.899486861523263 0.899486861523263 0.899486861523263 0.868339881569116 0.899486861523263
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Tk1 ENSMUSG00000025574 0.962174249500486 0.962174249500486 0.534776003057047 0.80216400458557 0.532314383313339 0.80216400458557
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Ak1 ENSMUSG00000026817 0.610369729061708 0.843475924621706 0.658308565535219 0.843475924621706 0.843475924621706 0.843475924621706
Txn1 ENSMUSG00000028367 0.334645252979498 0.652615428834331 0.652615428834331 0.652615428834331 0.504469647728879 0.652615428834331
Ak2 ENSMUSG00000028792 0.133901271809995 0.200851907714992 0.108248754101694 0.200851907714992 0.785163902554725 0.785163902554725
Gsr ENSMUSG00000031584 0.646932834355793 0.76415208338811 0.743161076756038 0.76415208338811 0.76415208338811 0.76415208338811
Nudt1 ENSMUSG00000036639 0.116491994026043 0.27714379501001 0.184762530006674 0.27714379501001 0.99685111991703 0.99685111991703
Nt5c1a ENSMUSG00000054958 0.987309934228535 0.987309934228535 0.37204385110793 0.987309934228535 0.930342343122478 0.987309934228535
Gpx1 ENSMUSG00000063856 0.574805433974788 0.582906160158444 0.395544061878369 0.582906160158444 0.582906160158444 0.582906160158444

Transport to the Golgi and subsequent modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Man1a ENSMUSG00000003746 0.779286627504559 0.98740515112606 0.77928192105922 0.98740515112606 0.98740515112606 0.98740515112606
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
B4galt5 ENSMUSG00000017929 0.514571378080404 0.877660077205933 0.877660077205933 0.877660077205933 0.70759985178933 0.877660077205933
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Man2a1 ENSMUSG00000024085 0.195523414879639 0.586570244638918 0.86833470967 0.924534855152377 0.924534855152377 0.924534855152377
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Fuca1 ENSMUSG00000028673 0.50442441281402 0.681404132696463 0.477005083446462 0.681404132696463 0.681404132696463 0.681404132696463
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
Arcn1 ENSMUSG00000032096 0.00893972140919316 0.0268191642275795 0.0903075846117496 0.135461376917624 0.933910122459056 0.933910122459056
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Mgat2 ENSMUSG00000043998 0.479500636817308 0.933946878912088 0.740209986526565 0.933946878912088 0.933946878912088 0.933946878912088
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Kdelr2 ENSMUSG00000079111 0.698869373150633 0.698869373150633 0.141618798356754 0.424856395070263 0.561602556176126 0.698869373150633

Regulation of TNFR1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ikbkg ENSMUSG00000004221 0.029774850671308 0.0644918716991508 0.0429945811327672 0.0644918716991508 0.649814571362946 0.649814571362946
Tax1bp1 ENSMUSG00000004535 0.367380786688448 0.60988798824112 0.406591992160746 0.60988798824112 0.962207152435869 0.962207152435869
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Tnfrsf1a ENSMUSG00000030341 0.971664717476175 0.971664717476175 0.208152371092993 0.624457113278978 0.855926077957422 0.971664717476175
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Metabolism of water-soluble vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acp5 ENSMUSG00000001348 0.993699729886046 0.993699729886046 0.570778064868416 0.993699729886046 0.899130931226438 0.993699729886046
Pank3 ENSMUSG00000018846 0.281752260876164 0.830148536824887 0.553432357883258 0.830148536824887 0.855927255547223 0.855927255547223
Mthfd1 ENSMUSG00000021048 0.601687599101695 0.601687599101695 0.271468633051307 0.601687599101695 0.582584269629009 0.601687599101695
Abcd4 ENSMUSG00000021240 0.26967271273366 0.40450906910049 0.224389239641765 0.40450906910049 0.66693677691282 0.66693677691282
Dhfr ENSMUSG00000021707 0.905716770880661 0.955939348685473 0.955939348685473 0.955939348685473 0.834252731128751 0.955939348685473
Slc52a2 ENSMUSG00000022560 0.219928164299355 0.379412289665751 0.252941526443834 0.379412289665751 0.57766299147477 0.57766299147477
Parp9 ENSMUSG00000022906 0.553456635671611 0.837334899865717 0.837334899865717 0.837334899865717 0.752049433052401 0.837334899865717
Shmt2 ENSMUSG00000025403 0.511697778241247 0.767546667361871 0.137201349124548 0.411604047373643 0.937038629669983 0.937038629669983
Ppcs ENSMUSG00000028636 0.303939401170929 0.455909101756394 0.111847346049347 0.335542038148041 0.591203546049003 0.591203546049003
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Parp16 ENSMUSG00000032392 0.865243441217051 0.924536619412128 0.413410611490329 0.924536619412128 0.924536619412128 0.924536619412128
Parp10 ENSMUSG00000063268 0.427105002397628 0.441050403041394 0.163271389873728 0.441050403041394 0.441050403041394 0.441050403041394

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcap31 ENSMUSG00000002015 0.758163089367248 0.849745868497015 0.849745868497015 0.849745868497015 0.535248350186248 0.849745868497015
Erap1 ENSMUSG00000021583 0.486947937822722 0.730421906734083 0.464909974696266 0.730421906734083 0.890137275886581 0.890137275886581
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
H2-T22 ENSMUSG00000056116 0.361253044476665 0.541879566714997 0.693008738474879 0.693008738474879 0.336774492562497 0.541879566714997
B2m ENSMUSG00000060802 0.259571155223671 0.450130329230997 0.354722498988373 0.450130329230997 0.450130329230997 0.450130329230997
H2-K1 ENSMUSG00000061232 0.752166193293213 0.752166193293213 0.472174679825948 0.708262019738922 0.417917860703482 0.708262019738922
H2-T23 ENSMUSG00000067212 0.276793072387045 0.541886744683004 0.361257829788669 0.541886744683004 0.583100639913956 0.583100639913956

Pentose phosphate pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rpe ENSMUSG00000026005 0.340654752603631 0.996850750704082 0.782280788924819 0.996850750704082 0.996850750704082 0.996850750704082
Pgd ENSMUSG00000028961 0.78535887978727 0.78535887978727 0.266381973037224 0.78535887978727 0.602208354073547 0.78535887978727
Rbks ENSMUSG00000029136 0.655506775251554 0.86524266630788 0.406643838104991 0.86524266630788 0.86524266630788 0.86524266630788
Dera ENSMUSG00000030225 0.968520644624679 0.968520644624679 0.874561002945649 0.968520644624679 0.943367606951117 0.968520644624679
Pgls ENSMUSG00000031807 0.367444654769433 0.640306024465269 0.426870682976846 0.640306024465269 0.930795478096443 0.930795478096443

Caspase activation via Death Receptors in the presence of ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Ly96 ENSMUSG00000025779 0.890135094068266 0.890135094068266 0.641318305023277 0.890135094068266 0.669844855533036 0.890135094068266
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

TRIF-mediated programmed cell death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Ly96 ENSMUSG00000025779 0.890135094068266 0.890135094068266 0.641318305023277 0.890135094068266 0.669844855533036 0.890135094068266
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Metabolism of vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acp5 ENSMUSG00000001348 0.993699729886046 0.993699729886046 0.570778064868416 0.993699729886046 0.899130931226438 0.993699729886046
Pank3 ENSMUSG00000018846 0.281752260876164 0.830148536824887 0.553432357883258 0.830148536824887 0.855927255547223 0.855927255547223
Mthfd1 ENSMUSG00000021048 0.601687599101695 0.601687599101695 0.271468633051307 0.601687599101695 0.582584269629009 0.601687599101695
Abcd4 ENSMUSG00000021240 0.26967271273366 0.40450906910049 0.224389239641765 0.40450906910049 0.66693677691282 0.66693677691282
Dhfr ENSMUSG00000021707 0.905716770880661 0.955939348685473 0.955939348685473 0.955939348685473 0.834252731128751 0.955939348685473
Slc52a2 ENSMUSG00000022560 0.219928164299355 0.379412289665751 0.252941526443834 0.379412289665751 0.57766299147477 0.57766299147477
Parp9 ENSMUSG00000022906 0.553456635671611 0.837334899865717 0.837334899865717 0.837334899865717 0.752049433052401 0.837334899865717
Shmt2 ENSMUSG00000025403 0.511697778241247 0.767546667361871 0.137201349124548 0.411604047373643 0.937038629669983 0.937038629669983
Lrat ENSMUSG00000028003 0.738823255408654 0.861467471950945 0.789768978862515 0.861467471950945 0.861467471950945 0.861467471950945
Ppcs ENSMUSG00000028636 0.303939401170929 0.455909101756394 0.111847346049347 0.335542038148041 0.591203546049003 0.591203546049003
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Pts ENSMUSG00000032067 0.984251336872471 0.984251336872471 0.915120087230139 0.984251336872471 0.886981863969416 0.984251336872471
Parp16 ENSMUSG00000032392 0.865243441217051 0.924536619412128 0.413410611490329 0.924536619412128 0.924536619412128 0.924536619412128
Gpc1 ENSMUSG00000034220 0.599326468547193 0.880737693466408 0.38015703293674 0.880737693466408 0.880737693466408 0.880737693466408
Parp10 ENSMUSG00000063268 0.427105002397628 0.441050403041394 0.163271389873728 0.441050403041394 0.441050403041394 0.441050403041394

Dimerization of procaspase-8

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

CASP8 activity is inhibited

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Regulation by c-FLIP

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

TNF signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ikbkg ENSMUSG00000004221 0.029774850671308 0.0644918716991508 0.0429945811327672 0.0644918716991508 0.649814571362946 0.649814571362946
Tax1bp1 ENSMUSG00000004535 0.367380786688448 0.60988798824112 0.406591992160746 0.60988798824112 0.962207152435869 0.962207152435869
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Tnfrsf1a ENSMUSG00000030341 0.971664717476175 0.971664717476175 0.208152371092993 0.624457113278978 0.855926077957422 0.971664717476175
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

TRAIL signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

TBC/RABGAPs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab8a ENSMUSG00000003037 0.482007272489392 0.80361477165696 0.638452186186988 0.80361477165696 0.80361477165696 0.80361477165696
Rab11a ENSMUSG00000004771 0.496786438140763 0.981108081083831 0.981108081083831 0.981108081083831 0.930797058758742 0.981108081083831
Gabarap ENSMUSG00000018567 0.785347023520285 0.785347023520285 0.782303548072425 0.785347023520285 0.566910245259418 0.785347023520285
Tbc1d15 ENSMUSG00000020130 0.767196264145037 0.767196264145037 0.472202030901251 0.767196264145037 0.649821690901183 0.767196264145037
Tbc1d7 ENSMUSG00000021368 0.042156178718098 0.063234268077147 0.0371569220325569 0.063234268077147 0.289198132046142 0.289198132046142
Tbc1d13 ENSMUSG00000039678 0.837357566832851 0.837357566832851 0.761179897794168 0.837357566832851 0.618742521930405 0.837357566832851

Zinc transporters

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc30a5 ENSMUSG00000021629 0.785340451449306 0.896320880645595 0.896320880645595 0.896320880645595 0.652481325446403 0.896320880645595
Slc30a6 ENSMUSG00000024069 0.946510665533973 0.946510665533973 0.477050187450355 0.946510665533973 0.69592134541924 0.946510665533973
Slc39a1 ENSMUSG00000052310 0.417937555883531 0.417937555883531 0.33076592857509 0.417937555883531 0.330753845505163 0.417937555883531
Slc39a8 ENSMUSG00000053897 0.785327796758932 0.871439336632888 0.871439336632888 0.871439336632888 0.782321323692487 0.871439336632888

Neutrophil degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cstb ENSMUSG00000005054 0.80656215294957 0.84967073233315 0.84967073233315 0.84967073233315 0.494322030821914 0.84967073233315
Surf4 ENSMUSG00000014867 0.837357083130926 0.837357083130926 0.153901599572923 0.46170479871877 0.535164953549068 0.802747430323602
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Rab5c ENSMUSG00000019173 0.971649645288956 0.971649645288956 0.713499994396498 0.971649645288956 0.629924096984163 0.971649645288956
Psmd12 ENSMUSG00000020720 0.281853419123783 0.834266670619335 0.55617778041289 0.834266670619335 0.858995601876688 0.858995601876688
Gdi2 ENSMUSG00000021218 0.902627377446034 0.905752580390091 0.859035880615437 0.905752580390091 0.905752580390091 0.905752580390091
Dnajc3 ENSMUSG00000022136 0.1470635192484 0.441190557745199 0.519727891237304 0.779591836855956 0.905752548968555 0.905752548968555
Gsdmd ENSMUSG00000022575 0.326762933930885 0.411021078857925 0.348873942705139 0.411021078857925 0.411021078857925 0.411021078857925
Lamtor2 ENSMUSG00000028062 0.452889805704408 0.540419868676426 0.300221363637933 0.540419868676426 0.540419868676426 0.540419868676426
Cpne3 ENSMUSG00000028228 0.583083208461065 0.604962986183158 0.604962986183158 0.604962986183158 0.548304055020299 0.604962986183158
Erp44 ENSMUSG00000028343 0.825057579666948 0.85901846449203 0.399946182285406 0.85901846449203 0.85901846449203 0.85901846449203
Alad ENSMUSG00000028393 0.0617687175798906 0.0926530763698359 0.00151445837037118 0.00454337511111355 0.638111751775025 0.638111751775025
Fuca1 ENSMUSG00000028673 0.50442441281402 0.681404132696463 0.477005083446462 0.681404132696463 0.681404132696463 0.681404132696463
Dera ENSMUSG00000030225 0.968520644624679 0.968520644624679 0.874561002945649 0.968520644624679 0.943367606951117 0.968520644624679
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
Magt1 ENSMUSG00000031232 0.429429722447548 0.968519007656914 0.828155030050808 0.968519007656914 0.968519007656914 0.968519007656914
Cmtm6 ENSMUSG00000032434 0.22577948660228 0.33866922990342 0.155029800383994 0.33866922990342 0.55610073633514 0.55610073633514
Dnajc13 ENSMUSG00000032560 0.186078503481381 0.558235510444144 0.834267622483318 0.834267622483318 0.728302103024868 0.834267622483318
Apeh ENSMUSG00000032590 0.782321228900727 0.782321228900727 0.0910736286877183 0.273220886063155 0.346831742844024 0.520247614266036
Grn ENSMUSG00000034708 0.800345485743071 0.800345485743071 0.158257239324568 0.474771717973705 0.797392393604005 0.800345485743071
Tspan14 ENSMUSG00000037824 0.871455331285827 0.871455331285827 0.342767073563302 0.52025077371919 0.346833849146126 0.52025077371919
Nhlrc3 ENSMUSG00000042997 0.354428629276173 0.962156788989988 0.962156788989988 0.962156788989988 0.946477445967538 0.962156788989988
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542
1600012H06Rik ENSMUSG00000050088 0.350900218001692 0.580123709753026 0.386749139835351 0.580123709753026 0.773237494403465 0.773237494403465
H2-T22 ENSMUSG00000056116 0.361253044476665 0.541879566714997 0.693008738474879 0.693008738474879 0.336774492562497 0.541879566714997
Gpr97 ENSMUSG00000060470 0.855835954485251 0.974793796240972 0.486796607526645 0.974793796240972 0.974793796240972 0.974793796240972
B2m ENSMUSG00000060802 0.259571155223671 0.450130329230997 0.354722498988373 0.450130329230997 0.450130329230997 0.450130329230997
H2-K1 ENSMUSG00000061232 0.752166193293213 0.752166193293213 0.472174679825948 0.708262019738922 0.417917860703482 0.708262019738922
Mospd2 ENSMUSG00000061778 0.420073079135234 0.630109618702851 0.219841224348346 0.630109618702851 0.675510043253844 0.675510043253844
H2-T23 ENSMUSG00000067212 0.276793072387045 0.541886744683004 0.361257829788669 0.541886744683004 0.583100639913956 0.583100639913956

Nucleobase catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nt5c ENSMUSG00000020736 0.803599085813525 0.899486861523263 0.899486861523263 0.899486861523263 0.868339881569116 0.899486861523263
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Nudt1 ENSMUSG00000036639 0.116491994026043 0.27714379501001 0.184762530006674 0.27714379501001 0.99685111991703 0.99685111991703
Nt5c1a ENSMUSG00000054958 0.987309934228535 0.987309934228535 0.37204385110793 0.987309934228535 0.930342343122478 0.987309934228535
Gpx1 ENSMUSG00000063856 0.574805433974788 0.582906160158444 0.395544061878369 0.582906160158444 0.582906160158444 0.582906160158444

Synthesis of dolichyl-phosphate-glucose

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nudt14 ENSMUSG00000002804 0.296482291573231 0.444723437359846 0.156087186687089 0.444723437359846 0.604942605857777 0.604942605857777
Alg5 ENSMUSG00000036632 0.846647634880647 0.959082682399838 0.474609558693488 0.959082682399838 0.959082682399838 0.959082682399838

Reactions specific to the complex N-glycan synthesis pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Man2a1 ENSMUSG00000024085 0.195523414879639 0.586570244638918 0.86833470967 0.924534855152377 0.924534855152377 0.924534855152377
Fuca1 ENSMUSG00000028673 0.50442441281402 0.681404132696463 0.477005083446462 0.681404132696463 0.681404132696463 0.681404132696463
Mgat2 ENSMUSG00000043998 0.479500636817308 0.933946878912088 0.740209986526565 0.933946878912088 0.933946878912088 0.933946878912088

Phosphate bond hydrolysis by NUDT proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Nudt1 ENSMUSG00000036639 0.116491994026043 0.27714379501001 0.184762530006674 0.27714379501001 0.99685111991703 0.99685111991703

Vesicle-mediated transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpd52l1 ENSMUSG00000000296 0.968516108965298 0.968516108965298 0.955932929536001 0.968516108965298 0.84354568843975 0.968516108965298
Snx9 ENSMUSG00000002365 0.933947916422629 0.933947916422629 0.309547192508182 0.928641577524545 0.782326845098921 0.933947916422629
Rab8a ENSMUSG00000003037 0.482007272489392 0.80361477165696 0.638452186186988 0.80361477165696 0.80361477165696 0.80361477165696
Akt2 ENSMUSG00000004056 0.593940298488105 0.890099435224894 0.229049055339806 0.687147166019417 0.890099435224894 0.890099435224894
Rab11a ENSMUSG00000004771 0.496786438140763 0.981108081083831 0.981108081083831 0.981108081083831 0.930797058758742 0.981108081083831
Vps4b ENSMUSG00000009907 0.386634745687049 0.664082478537564 0.664082478537564 0.664082478537564 0.550804069940743 0.664082478537564
Surf4 ENSMUSG00000014867 0.837357083130926 0.837357083130926 0.153901599572923 0.46170479871877 0.535164953549068 0.802747430323602
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Gabarap ENSMUSG00000018567 0.785347023520285 0.785347023520285 0.782303548072425 0.785347023520285 0.566910245259418 0.785347023520285
Rab5c ENSMUSG00000019173 0.971649645288956 0.971649645288956 0.713499994396498 0.971649645288956 0.629924096984163 0.971649645288956
Vps54 ENSMUSG00000020128 0.981108886655488 0.981108886655488 0.734261197137909 0.981108886655488 0.927676551816412 0.981108886655488
Tbc1d15 ENSMUSG00000020130 0.767196264145037 0.767196264145037 0.472202030901251 0.767196264145037 0.649821690901183 0.767196264145037
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Gdi2 ENSMUSG00000021218 0.902627377446034 0.905752580390091 0.859035880615437 0.905752580390091 0.905752580390091 0.905752580390091
Tbc1d7 ENSMUSG00000021368 0.042156178718098 0.063234268077147 0.0371569220325569 0.063234268077147 0.289198132046142 0.289198132046142
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Pacsin3 ENSMUSG00000027257 0.426600143959408 0.865139618544541 0.809703316551923 0.865139618544541 0.865139618544541 0.865139618544541
Tpd52 ENSMUSG00000027506 0.395534540955089 0.977960883244313 0.977960883244313 0.977960883244313 0.693015183470643 0.977960883244313
Chmp5 ENSMUSG00000028419 0.89010657221099 0.89010657221099 0.770174762238754 0.89010657221099 0.797498314206206 0.89010657221099
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
St5 ENSMUSG00000031024 0.678372593723222 0.678372593723222 0.050973784837344 0.152921354512032 0.548195203495481 0.678372593723222
Mvb12a ENSMUSG00000031813 0.342741770636901 0.365319664706036 0.31520447470145 0.365319664706036 0.365319664706036 0.365319664706036
Arcn1 ENSMUSG00000032096 0.00893972140919316 0.0268191642275795 0.0903075846117496 0.135461376917624 0.933910122459056 0.933910122459056
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Picalm ENSMUSG00000039361 0.0397914452029993 0.119374335608998 0.871434084417354 0.871434084417354 0.455265992600798 0.682898988901197
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Tbc1d13 ENSMUSG00000039678 0.837357566832851 0.837357566832851 0.761179897794168 0.837357566832851 0.618742521930405 0.837357566832851
Fcho2 ENSMUSG00000041685 0.348879664308865 0.686535183026556 0.880788811349441 0.880788811349441 0.457690122017704 0.686535183026556
Tbc1d8b ENSMUSG00000042473 0.149345226402698 0.448035679208095 0.386797144561621 0.477071330608438 0.477071330608438 0.477071330608438
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Chmp3 ENSMUSG00000053119 0.481765193301798 0.722647789952697 0.27662564227443 0.722647789952697 0.806534417638617 0.806534417638617
Stam2 ENSMUSG00000055371 0.129943786508122 0.389831359524367 0.369389228601134 0.554083842901701 0.752033452098773 0.752033452098773
Kdelr2 ENSMUSG00000079111 0.698869373150633 0.698869373150633 0.141618798356754 0.424856395070263 0.561602556176126 0.698869373150633

COPII-mediated vesicle transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524

Nicotinate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Parp9 ENSMUSG00000022906 0.553456635671611 0.837334899865717 0.837334899865717 0.837334899865717 0.752049433052401 0.837334899865717
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Parp16 ENSMUSG00000032392 0.865243441217051 0.924536619412128 0.413410611490329 0.924536619412128 0.924536619412128 0.924536619412128
Parp10 ENSMUSG00000063268 0.427105002397628 0.441050403041394 0.163271389873728 0.441050403041394 0.441050403041394 0.441050403041394

Rab regulation of trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab8a ENSMUSG00000003037 0.482007272489392 0.80361477165696 0.638452186186988 0.80361477165696 0.80361477165696 0.80361477165696
Akt2 ENSMUSG00000004056 0.593940298488105 0.890099435224894 0.229049055339806 0.687147166019417 0.890099435224894 0.890099435224894
Rab11a ENSMUSG00000004771 0.496786438140763 0.981108081083831 0.981108081083831 0.981108081083831 0.930797058758742 0.981108081083831
Gabarap ENSMUSG00000018567 0.785347023520285 0.785347023520285 0.782303548072425 0.785347023520285 0.566910245259418 0.785347023520285
Rab5c ENSMUSG00000019173 0.971649645288956 0.971649645288956 0.713499994396498 0.971649645288956 0.629924096984163 0.971649645288956
Tbc1d15 ENSMUSG00000020130 0.767196264145037 0.767196264145037 0.472202030901251 0.767196264145037 0.649821690901183 0.767196264145037
Gdi2 ENSMUSG00000021218 0.902627377446034 0.905752580390091 0.859035880615437 0.905752580390091 0.905752580390091 0.905752580390091
Tbc1d7 ENSMUSG00000021368 0.042156178718098 0.063234268077147 0.0371569220325569 0.063234268077147 0.289198132046142 0.289198132046142
St5 ENSMUSG00000031024 0.678372593723222 0.678372593723222 0.050973784837344 0.152921354512032 0.548195203495481 0.678372593723222
Tbc1d13 ENSMUSG00000039678 0.837357566832851 0.837357566832851 0.761179897794168 0.837357566832851 0.618742521930405 0.837357566832851

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nudt14 ENSMUSG00000002804 0.296482291573231 0.444723437359846 0.156087186687089 0.444723437359846 0.604942605857777 0.604942605857777
Mvd ENSMUSG00000006517 0.767192198620693 0.767192198620693 0.157355129810763 0.472065389432289 0.530029814345161 0.767192198620693
Gfpt2 ENSMUSG00000020363 0.98737533851357 0.98737533851357 0.955787648567063 0.98737533851357 0.788106507293002 0.98737533851357
Dpagt1 ENSMUSG00000032123 0.522315988902916 0.522315988902916 0.13628789903669 0.396998496635402 0.264665664423602 0.396998496635402
Alg5 ENSMUSG00000036632 0.846647634880647 0.959082682399838 0.474609558693488 0.959082682399838 0.959082682399838 0.959082682399838
Amdhd2 ENSMUSG00000036820 0.102313712342405 0.306941137027215 0.359164407298384 0.538746610947576 0.76721042868766 0.76721042868766
Dpm3 ENSMUSG00000042737 0.0530141839050926 0.159042551715278 0.303723784691225 0.455585677036838 0.462358669867307 0.462358669867307
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542

ER to Golgi Anterograde Transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctsz ENSMUSG00000016256 0.675614319108359 0.675614319108359 0.276735819771286 0.675614319108359 0.616001521092933 0.675614319108359
Scfd1 ENSMUSG00000020952 0.219879338027746 0.329819007041619 0.0268413662952607 0.080524098885782 0.577647509375013 0.577647509375013
Lman2 ENSMUSG00000021484 0.594003322923498 0.594003322923498 0.173175111712579 0.519525335137736 0.537851711603107 0.594003322923498
Tuba4a ENSMUSG00000026202 0.675610150001387 0.698867421657835 0.120250419115399 0.360751257346197 0.698867421657835 0.698867421657835
Ctsc ENSMUSG00000030560 0.151607918076064 0.454823754228191 0.371661417871565 0.557492126807347 0.987402968364068 0.987402968364068
Copb1 ENSMUSG00000030754 0.388791663802218 0.803555984119917 0.537744947374055 0.803555984119917 0.803555984119917 0.803555984119917
Arcn1 ENSMUSG00000032096 0.00893972140919316 0.0268191642275795 0.0903075846117496 0.135461376917624 0.933910122459056 0.933910122459056
Sec22a ENSMUSG00000034473 0.770197393595813 0.831217266104371 0.205301205544665 0.615903616633994 0.831217266104371 0.831217266104371
Sec31a ENSMUSG00000035325 0.501553295591716 0.809709258827714 0.809709258827714 0.809709258827714 0.806491221804969 0.809709258827714
Sec24c ENSMUSG00000039367 0.588410481984103 0.59110944694353 0.112798838856142 0.338396516568426 0.59110944694353 0.59110944694353
Preb ENSMUSG00000045302 0.112714220328799 0.169071330493199 0.0857910219291318 0.169071330493199 0.815809965857524 0.815809965857524
Kdelr2 ENSMUSG00000079111 0.698869373150633 0.698869373150633 0.141618798356754 0.424856395070263 0.561602556176126 0.698869373150633

Regulation of necroptotic cell death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mlkl ENSMUSG00000012519 0.952785792267244 0.952785792267244 0.908859482047486 0.952785792267244 0.408758355373737 0.952785792267244
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Signaling by Retinoic Acid

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlat ENSMUSG00000000168 0.503570854526072 0.632102801487263 0.0586095571332327 0.175828671399698 0.632102801487263 0.632102801487263
Rxrg ENSMUSG00000015843 0.51707726074314 0.852800818197242 0.852800818197242 0.852800818197242 0.638410120604844 0.852800818197242
Cpt1a ENSMUSG00000024900 0.24316739539351 0.330776493980017 0.276792049165963 0.330776493980017 0.330776493980017 0.330776493980017
Rdh5 ENSMUSG00000025350 0.522136920413624 0.522136920413624 0.369427697401649 0.522136920413624 0.252760694305914 0.522136920413624
Rdh10 ENSMUSG00000025921 0.806617757263259 0.984254513163533 0.438668004095544 0.984254513163533 0.984254513163533 0.984254513163533
Dhrs9 ENSMUSG00000027068 0.243752118116576 0.729552308658135 0.48636820577209 0.729552308658135 0.772287355189387 0.772287355189387

RIPK1-mediated regulated necrosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mlkl ENSMUSG00000012519 0.952785792267244 0.952785792267244 0.908859482047486 0.952785792267244 0.408758355373737 0.952785792267244
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Regulated Necrosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mlkl ENSMUSG00000012519 0.952785792267244 0.952785792267244 0.908859482047486 0.952785792267244 0.408758355373737 0.952785792267244
Ripk1 ENSMUSG00000021408 0.269704254512339 0.809112763537016 0.883896375614469 0.883896375614469 0.809681377436591 0.883896375614469
Casp8 ENSMUSG00000026029 0.8776145194122 0.8776145194122 0.80973877430573 0.8776145194122 0.566764729115625 0.8776145194122
Cflar ENSMUSG00000026031 0.74916873076657 0.815865723778173 0.815865723778173 0.815865723778173 0.54833880124904 0.815865723778173
Fadd ENSMUSG00000031077 0.212218477556202 0.318327716334303 0.18208750449748 0.318327716334303 0.940204927817945 0.940204927817945

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlat ENSMUSG00000000168 0.503570854526072 0.632102801487263 0.0586095571332327 0.175828671399698 0.632102801487263 0.632102801487263
Gmpr ENSMUSG00000000253 0.399978623586033 0.59996793537905 0.173169604896188 0.519508814688563 0.893258653663041 0.893258653663041
Acp5 ENSMUSG00000001348 0.993699729886046 0.993699729886046 0.570778064868416 0.993699729886046 0.899130931226438 0.993699729886046
Naglu ENSMUSG00000001751 0.102276109935138 0.306828329805416 0.27845931592216 0.41768897388324 0.825041584064722 0.825041584064722
Lpcat3 ENSMUSG00000004270 0.666830152414596 0.666830152414596 0.494350188390407 0.666830152414596 0.643982287880309 0.666830152414596
Elovl1 ENSMUSG00000006390 0.874517531499764 0.874517531499764 0.540302988965073 0.810454483447609 0.530020246503933 0.810454483447609
Mvd ENSMUSG00000006517 0.767192198620693 0.767192198620693 0.157355129810763 0.472065389432289 0.530029814345161 0.767192198620693
Acot8 ENSMUSG00000017307 0.72827289083604 0.72827289083604 0.664052844072961 0.72827289083604 0.285601269668361 0.72827289083604
B4galt5 ENSMUSG00000017929 0.514571378080404 0.877660077205933 0.877660077205933 0.877660077205933 0.70759985178933 0.877660077205933
Pank3 ENSMUSG00000018846 0.281752260876164 0.830148536824887 0.553432357883258 0.830148536824887 0.855927255547223 0.855927255547223
Sgpl1 ENSMUSG00000020097 0.410010139296769 0.865183077505041 0.784772702761252 0.865183077505041 0.865183077505041 0.865183077505041
Psmd12 ENSMUSG00000020720 0.281853419123783 0.834266670619335 0.55617778041289 0.834266670619335 0.858995601876688 0.858995601876688
Nt5c ENSMUSG00000020736 0.803599085813525 0.899486861523263 0.899486861523263 0.899486861523263 0.868339881569116 0.899486861523263
Adprm ENSMUSG00000020910 0.996850973302291 0.996850973302291 0.38457166624462 0.57685749936693 0.222885045267451 0.57685749936693
Mthfd1 ENSMUSG00000021048 0.601687599101695 0.601687599101695 0.271468633051307 0.601687599101695 0.582584269629009 0.601687599101695
Sgpp1 ENSMUSG00000021054 0.484473238419926 0.716438618279956 0.701747400817793 0.716438618279956 0.716438618279956 0.716438618279956
Abcd4 ENSMUSG00000021240 0.26967271273366 0.40450906910049 0.224389239641765 0.40450906910049 0.66693677691282 0.66693677691282
Slc35b3 ENSMUSG00000021432 0.417625225091943 0.924501445292485 0.855915701188369 0.924501445292485 0.924501445292485 0.924501445292485
Sptlc1 ENSMUSG00000021468 0.749112639819611 0.965368862697293 0.965368862697293 0.965368862697293 0.604949386196136 0.965368862697293
Dhfr ENSMUSG00000021707 0.905716770880661 0.955939348685473 0.955939348685473 0.955939348685473 0.834252731128751 0.955939348685473
Slc52a2 ENSMUSG00000022560 0.219928164299355 0.379412289665751 0.252941526443834 0.379412289665751 0.57766299147477 0.57766299147477
Parp9 ENSMUSG00000022906 0.553456635671611 0.837334899865717 0.837334899865717 0.837334899865717 0.752049433052401 0.837334899865717
Cyp4f13 ENSMUSG00000024055 0.298365819328683 0.651093408225967 0.902627669517185 0.902627669517185 0.434062272150645 0.651093408225967
Cpt1a ENSMUSG00000024900 0.24316739539351 0.330776493980017 0.276792049165963 0.330776493980017 0.330776493980017 0.330776493980017
Acsl5 ENSMUSG00000024981 0.828128391170635 0.828128391170635 0.695908595172244 0.828128391170635 0.607744718414025 0.828128391170635
Got1 ENSMUSG00000025190 0.782278986854115 0.782278986854115 0.127864751830479 0.383594255491437 0.433782656373795 0.650673984560693
Sacm1l ENSMUSG00000025240 0.0918401354358094 0.275520406307428 0.616062570758635 0.698853312197103 0.698853312197103 0.698853312197103
Ormdl2 ENSMUSG00000025353 0.716482837530236 0.984253222477513 0.984253222477513 0.984253222477513 0.66690732279783 0.984253222477513
Shmt2 ENSMUSG00000025403 0.511697778241247 0.767546667361871 0.137201349124548 0.411604047373643 0.937038629669983 0.937038629669983
Phkg1 ENSMUSG00000025537 0.529771232859317 0.880682681912939 0.880682681912939 0.880682681912939 0.785351583855423 0.880682681912939
Tk1 ENSMUSG00000025574 0.962174249500486 0.962174249500486 0.534776003057047 0.80216400458557 0.532314383313339 0.80216400458557
Nudt5 ENSMUSG00000025817 0.952729971914693 0.952729971914693 0.585291705097688 0.952729971914693 0.7223379433625 0.952729971914693
Rpe ENSMUSG00000026005 0.340654752603631 0.996850750704082 0.782280788924819 0.996850750704082 0.996850750704082 0.996850750704082
Ormdl1 ENSMUSG00000026097 0.758167616525327 0.831212698775166 0.669852108338679 0.831212698775166 0.831212698775166 0.831212698775166
Ak1 ENSMUSG00000026817 0.610369729061708 0.843475924621706 0.658308565535219 0.843475924621706 0.843475924621706 0.843475924621706
Chac1 ENSMUSG00000027313 0.902583883612485 0.97164355198828 0.420076774600191 0.97164355198828 0.97164355198828 0.97164355198828
Lrat ENSMUSG00000028003 0.738823255408654 0.861467471950945 0.789768978862515 0.861467471950945 0.861467471950945 0.861467471950945
Gclm ENSMUSG00000028124 0.386679585373224 0.586625824157339 0.39108388277156 0.586625824157339 0.955920338679395 0.955920338679395
Cpne3 ENSMUSG00000028228 0.583083208461065 0.604962986183158 0.604962986183158 0.604962986183158 0.548304055020299 0.604962986183158
Txn1 ENSMUSG00000028367 0.334645252979498 0.652615428834331 0.652615428834331 0.652615428834331 0.504469647728879 0.652615428834331
Alad ENSMUSG00000028393 0.0617687175798906 0.0926530763698359 0.00151445837037118 0.00454337511111355 0.638111751775025 0.638111751775025
Ppcs ENSMUSG00000028636 0.303939401170929 0.455909101756394 0.111847346049347 0.335542038148041 0.591203546049003 0.591203546049003
Fabp3 ENSMUSG00000028773 0.809388939290358 0.809388939290358 0.692573480825513 0.809388939290358 0.722261235415398 0.809388939290358
Ak2 ENSMUSG00000028792 0.133901271809995 0.200851907714992 0.108248754101694 0.200851907714992 0.785163902554725 0.785163902554725
Mecr ENSMUSG00000028910 0.157249082739605 0.235873624109407 0.0665604409689729 0.199681322906919 0.427117417047903 0.427117417047903
Pgd ENSMUSG00000028961 0.78535887978727 0.78535887978727 0.266381973037224 0.78535887978727 0.602208354073547 0.78535887978727
Nadk ENSMUSG00000029063 0.837380815265994 0.837380815265994 0.175628720668848 0.526318035232073 0.350878690154715 0.526318035232073
Rbks ENSMUSG00000029136 0.655506775251554 0.86524266630788 0.406643838104991 0.86524266630788 0.86524266630788 0.86524266630788
Pi4k2b ENSMUSG00000029186 0.974801453908087 0.974801453908087 0.678470451430415 0.974801453908087 0.469598984596345 0.974801453908087
Akr1b8 ENSMUSG00000029762 0.959080171784373 0.959080171784373 0.477085523196963 0.838361782298142 0.558907854865428 0.838361782298142
Dera ENSMUSG00000030225 0.968520644624679 0.968520644624679 0.874561002945649 0.968520644624679 0.943367606951117 0.968520644624679
Itpr2 ENSMUSG00000030287 0.632761140357658 0.632761140357658 0.457632207224365 0.632761140357658 0.501910077658152 0.632761140357658
Nadsyn1 ENSMUSG00000031090 0.930812381711891 0.930812381711891 0.83122452479565 0.930812381711891 0.519727471072072 0.930812381711891
Awat2 ENSMUSG00000031220 0.139312067136946 0.417936201410839 0.795514936285472 0.795514936285472 0.527322791976981 0.790984187965471
Gsr ENSMUSG00000031584 0.646932834355793 0.76415208338811 0.743161076756038 0.76415208338811 0.76415208338811 0.76415208338811
Hpgd ENSMUSG00000031613 0.328551058743655 0.551046701732496 0.880758627095807 0.880758627095807 0.367364467821664 0.551046701732496
Pgls ENSMUSG00000031807 0.367444654769433 0.640306024465269 0.426870682976846 0.640306024465269 0.930795478096443 0.930795478096443
Pts ENSMUSG00000032067 0.984251336872471 0.984251336872471 0.915120087230139 0.984251336872471 0.886981863969416 0.984251336872471
Parp16 ENSMUSG00000032392 0.865243441217051 0.924536619412128 0.413410611490329 0.924536619412128 0.924536619412128 0.924536619412128
Pfkm ENSMUSG00000033065 0.375894813643832 0.563842220465748 0.177804478455957 0.533413435367871 0.731099043606285 0.731099043606285
Gpc1 ENSMUSG00000034220 0.599326468547193 0.880737693466408 0.38015703293674 0.880737693466408 0.880737693466408 0.880737693466408
Slc25a21 ENSMUSG00000035472 0.675830968803318 0.895532340676718 0.284267235504645 0.852801706513934 0.895532340676718 0.895532340676718
Nudt1 ENSMUSG00000036639 0.116491994026043 0.27714379501001 0.184762530006674 0.27714379501001 0.99685111991703 0.99685111991703
Smpd1 ENSMUSG00000037049 0.646943756363319 0.728266417400137 0.191327285320162 0.573981855960487 0.728266417400137 0.728266417400137
Kmo ENSMUSG00000039783 0.525869360757365 0.788804041136048 0.370962318545351 0.788804041136048 0.806355122990017 0.806355122990017
Hs6st1 ENSMUSG00000045216 0.526884143119878 0.736724206782581 0.413264614968849 0.736724206782581 0.736724206782581 0.736724206782581
Glb1 ENSMUSG00000045594 0.692996628598359 0.834310193990542 0.359089169203224 0.834310193990542 0.834310193990542 0.834310193990542
Stard5 ENSMUSG00000046027 0.89638054392709 0.943369513189705 0.943369513189705 0.943369513189705 0.472200940902392 0.943369513189705
Nat2 ENSMUSG00000051147 0.83429746610403 0.899489753459833 0.821987601659315 0.899489753459833 0.899489753459833 0.899489753459833
Gnpda1 ENSMUSG00000052102 0.852842597710133 0.908882654894043 0.484478026561191 0.908882654894043 0.908882654894043 0.908882654894043
Nt5c1a ENSMUSG00000054958 0.987309934228535 0.987309934228535 0.37204385110793 0.987309934228535 0.930342343122478 0.987309934228535
Parp10 ENSMUSG00000063268 0.427105002397628 0.441050403041394 0.163271389873728 0.441050403041394 0.441050403041394 0.441050403041394
Gpx1 ENSMUSG00000063856 0.574805433974788 0.582906160158444 0.395544061878369 0.582906160158444 0.582906160158444 0.582906160158444
Ppp1r3c ENSMUSG00000067279 0.477017457385109 0.638291312274782 0.450006147339908 0.638291312274782 0.638291312274782 0.638291312274782
Seh1l ENSMUSG00000079614 0.716480807352623 0.990553637130846 0.990553637130846 0.990553637130846 0.514625829809495 0.990553637130846
Kcnj11 ENSMUSG00000096146 0.968422986227814 0.974732682720661 0.82467293446919 0.974732682720661 0.974732682720661 0.974732682720661

orangered4

Fluid shear stress and atherosclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pecam1 ENSMUSG00000020717 0.977952381600213 0.977952381600213 0.486942237919698 0.730413356879546 0.363263050231256 0.730413356879546
Nos3 ENSMUSG00000028978 0.968496876526708 0.981101774241963 0.15038429252282 0.451152877568461 0.981101774241963 0.981101774241963
Cdh5 ENSMUSG00000031871 0.911967104342648 0.927641159855616 0.168193830168985 0.504581490506954 0.927641159855616 0.927641159855616
Kdr ENSMUSG00000062960 0.125001922349865 0.187502883524798 0.0360691742988581 0.108207522896574 0.433883988738066 0.433883988738066
Thbd ENSMUSG00000074743 0.921404408494505 0.921404408494505 0.0401741420239671 0.120522426071901 0.918254779598325 0.921404408494505

Apelin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctgf ENSMUSG00000019997 0.0747296730617086 0.224189019185126 0.382411633941079 0.573617450911618 0.987403903771522 0.987403903771522
Adcy4 ENSMUSG00000022220 0.33199202046791 0.481144418841354 0.0408545192732073 0.122563557819622 0.481144418841354 0.481144418841354
Nos3 ENSMUSG00000028978 0.968496876526708 0.981101774241963 0.15038429252282 0.451152877568461 0.981101774241963 0.981101774241963
Aplnr ENSMUSG00000044338 0.574464026681545 0.675835382816563 0.148335140908563 0.44500542272569 0.675835382816563 0.675835382816563

pink

Complement and coagulation cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
C4a ENSMUSG00000015451 0.690072349221893 0.855927494244339 0.855927494244339 0.855927494244339 0.837393384610836 0.855927494244339
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
F12 ENSMUSG00000021492 0.780292597460224 0.984089396276371 0.820417084796806 0.984089396276371 0.984089396276371 0.984089396276371
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
C6 ENSMUSG00000022181 0.914593164198867 0.980887905229622 0.453633067649645 0.980887905229622 0.980887905229622 0.980887905229622
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Masp1 ENSMUSG00000022887 0.569582207383391 0.937086821458048 0.803600869461786 0.937086821458048 0.937086821458048 0.937086821458048
C4bp ENSMUSG00000026405 0.602677044932206 0.904015567398309 0.526728907679196 0.904015567398309 0.990465487521565 0.990465487521565
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
Hc ENSMUSG00000026874 0.924121232478127 0.924121232478127 0.849036562644297 0.924121232478127 0.880695899043171 0.924121232478127
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Masp2 ENSMUSG00000028979 0.971656010064839 0.971656010064839 0.577630409042643 0.971656010064839 0.815774120725749 0.971656010064839
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Cfhr2 ENSMUSG00000033898 0.468201428882702 0.993588475222047 0.993588475222047 0.993588475222047 0.769011903504606 0.993588475222047
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594
Vsig4 ENSMUSG00000044206 0.587249252523071 0.809605705515279 0.675105508078151 0.809605705515279 0.809605705515279 0.809605705515279
Cfi ENSMUSG00000058952 0.600963382222105 0.882365843940303 0.814857240977372 0.882365843940303 0.882365843940303 0.882365843940303
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Serpina1a ENSMUSG00000066366 0.236980419391318 0.710941258173954 0.499300840277379 0.748951260416068 0.788246252811631 0.788246252811631
Serpina1b ENSMUSG00000071178 0.774845812471959 0.818619945087551 0.438418767790548 0.818619945087551 0.818619945087551 0.818619945087551
Serpina1e ENSMUSG00000072849 0.118629085574276 0.355887256722828 0.606962328771568 0.910443493157352 0.940143683250321 0.940143683250321
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881
Serpina1c ENSMUSG00000079015 0.595979614142906 0.595979614142906 0.188125794712535 0.564377384137605 0.455079934966981 0.595979614142906

Chemical carcinogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
2810007J24Rik ENSMUSG00000030378 0.866668270424591 0.866668270424591 0.706346348608568 0.866668270424591 0.821048145387667 0.866668270424591
Cyp2b10 ENSMUSG00000030483 0.913496077505537 0.984004730274599 0.890852807793166 0.984004730274599 0.984004730274599 0.984004730274599
Sult1a1 ENSMUSG00000030711 0.940212988464528 0.940212988464528 0.25954726393901 0.778641791817029 0.918242193122088 0.940212988464528
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Ccbl2 ENSMUSG00000040213 0.748904577539404 0.748904577539404 0.556150395458649 0.748904577539404 0.745879617001619 0.748904577539404
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Cyp2c50 ENSMUSG00000054827 0.906956565173568 0.906956565173568 0.447611057878194 0.906956565173568 0.817202840452684 0.906956565173568
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Bile secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Abcc3 ENSMUSG00000020865 0.644134885862136 0.644134885862136 0.41228060644594 0.644134885862136 0.606796141390161 0.644134885862136
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
2810007J24Rik ENSMUSG00000030378 0.866668270424591 0.866668270424591 0.706346348608568 0.866668270424591 0.821048145387667 0.866668270424591
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Aqp8 ENSMUSG00000030762 0.350246506834888 0.350246506834888 0.191087507965486 0.350246506834888 0.276228338155824 0.350246506834888
Aqp9 ENSMUSG00000032204 0.568710953423365 0.683960988228502 0.683960988228502 0.683960988228502 0.401336329005836 0.683960988228502
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Nr0b2 ENSMUSG00000037583 0.558009136148516 0.588114337433216 0.584708367822691 0.588114337433216 0.588114337433216 0.588114337433216
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Metabolism of xenobiotics by cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Dhdh ENSMUSG00000011382 0.779252522977749 0.779252522977749 0.773221801768075 0.779252522977749 0.564245404879385 0.779252522977749
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
2810007J24Rik ENSMUSG00000030378 0.866668270424591 0.866668270424591 0.706346348608568 0.866668270424591 0.821048145387667 0.866668270424591
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Cyp2f2 ENSMUSG00000052974 0.49161741983438 0.955068462470323 0.636712308313548 0.955068462470323 0.990512657507331 0.990512657507331
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pemt ENSMUSG00000000301 0.761183182115839 0.981108783328759 0.469693086782545 0.981108783328759 0.981108783328759 0.981108783328759
Ftcd ENSMUSG00000001155 0.632321655854328 0.786163114393065 0.704172496637062 0.786163114393065 0.786163114393065 0.786163114393065
Tat ENSMUSG00000001670 0.151362477657136 0.454087432971407 0.643003409026857 0.643003409026857 0.557814313289308 0.643003409026857
Idh3g ENSMUSG00000002010 0.695598092746212 0.745911614681288 0.745911614681288 0.745911614681288 0.632642939869658 0.745911614681288
Gnmt ENSMUSG00000002769 0.516716224222671 0.571831376854682 0.571831376854682 0.571831376854682 0.292415180350565 0.571831376854682
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp17a1 ENSMUSG00000003555 0.389420562143718 0.406358017223015 0.181129646960049 0.406358017223015 0.406358017223015 0.406358017223015
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Hyal1 ENSMUSG00000010051 0.825077875461598 0.825077875461598 0.507000703324683 0.760501054987025 0.431746903053683 0.760501054987025
Dhdh ENSMUSG00000011382 0.779252522977749 0.779252522977749 0.773221801768075 0.779252522977749 0.564245404879385 0.779252522977749
Amdhd1 ENSMUSG00000015890 0.742590574122166 0.742590574122166 0.549473333106631 0.742590574122166 0.637861074076197 0.742590574122166
Qrsl1 ENSMUSG00000019863 0.722357660548768 0.722357660548768 0.556276942443834 0.722357660548768 0.309523279552689 0.722357660548768
Arg1 ENSMUSG00000019987 0.291428895857939 0.874286687573818 0.958952177959993 0.958952177959993 0.659990777326478 0.958952177959993
Hal ENSMUSG00000020017 0.663138111797486 0.663138111797486 0.552623819540299 0.663138111797486 0.378376707153874 0.663138111797486
Gamt ENSMUSG00000020150 0.221430590061347 0.33214588509202 0.0486822048248833 0.14604661447465 0.596700979953383 0.596700979953383
Adi1 ENSMUSG00000020629 0.376008097372252 0.464911672550297 0.0180877329853707 0.0542631989561121 0.464911672550297 0.464911672550297
Pygl ENSMUSG00000021069 0.467328931734958 0.644095199602022 0.644095199602022 0.644095199602022 0.524829229050038 0.644095199602022
Coq6 ENSMUSG00000021235 0.202352369075743 0.202352369075743 0.00476879790864588 0.0143063937259376 0.101420611770647 0.152130917655971
Elovl2 ENSMUSG00000021364 0.911758016272639 0.911758016272639 0.778762754215036 0.911758016272639 0.710227553933736 0.911758016272639
Gpx8 ENSMUSG00000021760 0.501885588706087 0.532640609557704 0.532640609557704 0.532640609557704 0.359058969939724 0.532640609557704
Oxct1 ENSMUSG00000022186 0.0752796906043998 0.225839071813199 0.78833637711065 0.91511665827977 0.91511665827977 0.91511665827977
Tymp ENSMUSG00000022615 0.0892663146705974 0.267798944011792 0.344421448552506 0.516632172828759 0.949571322507187 0.949571322507187
Rgn ENSMUSG00000023070 0.657373786046955 0.707611446511957 0.66613887252376 0.707611446511957 0.707611446511957 0.707611446511957
Glo1 ENSMUSG00000024026 0.669809139782919 0.749174714108576 0.319055685172727 0.749174714108576 0.749174714108576 0.749174714108576
Cyp26a1 ENSMUSG00000024987 0.604267678116927 0.765632306349339 0.765632306349339 0.765632306349339 0.608028071060317 0.765632306349339
Car5a ENSMUSG00000025317 0.411667270479958 0.883522439262698 0.883522439262698 0.883522439262698 0.747324037409172 0.883522439262698
Urah ENSMUSG00000025481 0.454922191755884 0.974801577770295 0.974801577770295 0.974801577770295 0.710404731786992 0.974801577770295
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Kynu ENSMUSG00000026866 0.977727420064452 0.99051026338415 0.99051026338415 0.99051026338415 0.857826543462636 0.99051026338415
Hao1 ENSMUSG00000027261 0.95416040513411 0.95416040513411 0.928131198252319 0.95416040513411 0.229373904811969 0.688121714435906
Acss1 ENSMUSG00000027452 0.852824011763922 0.852824011763922 0.334788274939822 0.852824011763922 0.687181916981449 0.852824011763922
Hmgcs2 ENSMUSG00000027875 0.189976511224712 0.569929533674135 0.652576611045286 0.710570408299713 0.710570408299713 0.710570408299713
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Tdo2 ENSMUSG00000028011 0.426369423436919 0.5990459917723 0.47441542546469 0.5990459917723 0.5990459917723 0.5990459917723
Uox ENSMUSG00000028186 0.560592223843468 0.763557409057687 0.763557409057687 0.763557409057687 0.621624907833903 0.763557409057687
Gne ENSMUSG00000028479 0.638156742131669 0.638156742131669 0.427043331260741 0.638156742131669 0.338449835183376 0.638156742131669
Sds ENSMUSG00000029597 0.757630750935161 0.990426195060373 0.722291376566824 0.990426195060373 0.990426195060373 0.990426195060373
Ldhb ENSMUSG00000030246 0.930675665505726 0.930675665505726 0.858920702354651 0.930675665505726 0.707185278201982 0.930675665505726
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Cyp2b10 ENSMUSG00000030483 0.913496077505537 0.984004730274599 0.890852807793166 0.984004730274599 0.984004730274599 0.984004730274599
Me3 ENSMUSG00000030621 0.577434373307305 0.911885418272329 0.743025519839971 0.911885418272329 0.911885418272329 0.911885418272329
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Lipc ENSMUSG00000032207 0.775011478313671 0.799943403051277 0.674420969809841 0.799943403051277 0.799943403051277 0.799943403051277
Nnmt ENSMUSG00000032271 0.476576588548111 0.476576588548111 0.358473663313352 0.476576588548111 0.217949184221594 0.476576588548111
Idh3a ENSMUSG00000032279 0.464642363777259 0.87138171210917 0.701795742495507 0.87138171210917 0.87138171210917 0.87138171210917
Mpi ENSMUSG00000032306 0.862113402233359 0.862113402233359 0.767197551937537 0.862113402233359 0.613249211642643 0.862113402233359
Gulo ENSMUSG00000034450 0.354318856254938 0.815141973081422 0.923792695568754 0.923792695568754 0.543427982054281 0.815141973081422
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Scd1 ENSMUSG00000037071 0.627130562693556 0.993701875928424 0.993701875928424 0.993701875928424 0.728267379696892 0.993701875928424
Gch1 ENSMUSG00000037580 0.710158148453647 0.710158148453647 0.332495446876071 0.710158148453647 0.516447590235188 0.710158148453647
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Elovl3 ENSMUSG00000038754 0.782935775862553 0.851777667560445 0.851777667560445 0.851777667560445 0.653560408657682 0.851777667560445
Atp6v1g1 ENSMUSG00000039105 0.739905344599766 0.996847787027275 0.424716839813708 0.996847787027275 0.996847787027275 0.996847787027275
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Rdh7 ENSMUSG00000040134 0.743716043852097 0.922806505411945 0.922806505411945 0.922806505411945 0.850457166602334 0.922806505411945
Ccbl2 ENSMUSG00000040213 0.748904577539404 0.748904577539404 0.556150395458649 0.748904577539404 0.745879617001619 0.748904577539404
Sgms1 ENSMUSG00000040451 0.452748404705691 0.679122607058537 0.933927805028281 0.933927805028281 0.334611881225443 0.679122607058537
Agmat ENSMUSG00000040706 0.874315257799446 0.927403291801747 0.115556678094432 0.346670034283297 0.927403291801747 0.927403291801747
Bbox1 ENSMUSG00000041660 0.641458628512556 0.84873787883349 0.84873787883349 0.84873787883349 0.614398935341444 0.84873787883349
Cox10 ENSMUSG00000042148 0.506251214728852 0.751855495734691 0.081505776059439 0.244517328178317 0.751855495734691 0.751855495734691
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437
Cox17 ENSMUSG00000046516 0.346024462787079 0.519036694180619 0.0297579346096359 0.0892738038289076 0.689528183565093 0.689528183565093
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Cyp2c50 ENSMUSG00000054827 0.906956565173568 0.906956565173568 0.447611057878194 0.906956565173568 0.817202840452684 0.906956565173568
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663
Aox3 ENSMUSG00000064294 0.81585938285688 0.981108338371844 0.755173742031336 0.981108338371844 0.981108338371844 0.981108338371844
Pde7a ENSMUSG00000069094 0.203077276679066 0.558159070776385 0.388892814788727 0.558159070776385 0.558159070776385 0.558159070776385
Etnk2 ENSMUSG00000070644 0.846608146393741 0.846608146393741 0.245702708267281 0.737108124801842 0.590751046168787 0.846608146393741
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774
Bhmt ENSMUSG00000074768 0.987220246262762 0.987373460396975 0.745754825898419 0.987373460396975 0.987373460396975 0.987373460396975

Retinol metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp26a1 ENSMUSG00000024987 0.604267678116927 0.765632306349339 0.765632306349339 0.765632306349339 0.608028071060317 0.765632306349339
Cyp2b10 ENSMUSG00000030483 0.913496077505537 0.984004730274599 0.890852807793166 0.984004730274599 0.984004730274599 0.984004730274599
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Rdh7 ENSMUSG00000040134 0.743716043852097 0.922806505411945 0.922806505411945 0.922806505411945 0.850457166602334 0.922806505411945
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Cyp2c50 ENSMUSG00000054827 0.906956565173568 0.906956565173568 0.447611057878194 0.906956565173568 0.817202840452684 0.906956565173568
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Aox3 ENSMUSG00000064294 0.81585938285688 0.981108338371844 0.755173742031336 0.981108338371844 0.981108338371844 0.981108338371844
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Amoebiasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
Arg1 ENSMUSG00000019987 0.291428895857939 0.874286687573818 0.958952177959993 0.958952177959993 0.659990777326478 0.958952177959993
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
Il1r1 ENSMUSG00000026072 0.0659955253912233 0.19798657617367 0.871381997146639 0.871381997146639 0.459711154432572 0.689566731648858
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Lamc1 ENSMUSG00000026478 0.493007228412232 0.501628765666281 0.168544269075368 0.501628765666281 0.501628765666281 0.501628765666281
Cd1d1 ENSMUSG00000028076 0.469459007619073 0.704188511428609 0.21799028774152 0.653970863224561 0.746063692406571 0.746063692406571
Cxcl1 ENSMUSG00000029380 0.353240982701273 0.955173555000085 0.955173555000085 0.955173555000085 0.733638415698664 0.955173555000085
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
Col4a1 ENSMUSG00000031502 0.827618285628854 0.827618285628854 0.0445234387141291 0.133570316142387 0.604046364232818 0.827618285628854
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594
Lamb2 ENSMUSG00000052911 0.410690749650905 0.616036124476358 0.0907310861443944 0.272193258433183 0.803448030246651 0.803448030246651
Serpinb6a ENSMUSG00000060147 0.896350471865836 0.927659490866606 0.773240696582001 0.927659490866606 0.927659490866606 0.927659490866606

Drug metabolism - cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Aox3 ENSMUSG00000064294 0.81585938285688 0.981108338371844 0.755173742031336 0.981108338371844 0.981108338371844 0.981108338371844
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Drug metabolism - other enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Tymp ENSMUSG00000022615 0.0892663146705974 0.267798944011792 0.344421448552506 0.516632172828759 0.949571322507187 0.949571322507187
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Ces2g ENSMUSG00000031877 0.894933937818049 0.894933937818049 0.611492717163467 0.894933937818049 0.683348334876846 0.894933937818049
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Ces1c ENSMUSG00000057400 0.671652204593182 0.974756421838924 0.974756421838924 0.974756421838924 0.971613067780585 0.974756421838924
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Steroid hormone biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp17a1 ENSMUSG00000003555 0.389420562143718 0.406358017223015 0.181129646960049 0.406358017223015 0.406358017223015 0.406358017223015
Cyp2b10 ENSMUSG00000030483 0.913496077505537 0.984004730274599 0.890852807793166 0.984004730274599 0.984004730274599 0.984004730274599
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Cyp2c50 ENSMUSG00000054827 0.906956565173568 0.906956565173568 0.447611057878194 0.906956565173568 0.817202840452684 0.906956565173568
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774
Cyp2d10 ENSMUSG00000094806 0.88796863996674 0.942237840656208 0.942237840656208 0.942237840656208 0.450169529530623 0.942237840656208

Cholesterol metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoh ENSMUSG00000000049 0.943315964359844 0.943315964359844 0.629805577436838 0.943315964359844 0.635532027271455 0.943315964359844
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Vdac2 ENSMUSG00000021771 0.843442684108156 0.843442684108156 0.273237046821067 0.8197111404632 0.776132053097756 0.843442684108156
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Angptl3 ENSMUSG00000028553 0.965163649621279 0.965163649621279 0.244817865150009 0.37623230233663 0.250821534891086 0.37623230233663
Apoc3 ENSMUSG00000032081 0.249260126876618 0.747780380629853 0.527409784444452 0.791114676666678 0.86515846438042 0.86515846438042
Lipc ENSMUSG00000032207 0.775011478313671 0.799943403051277 0.674420969809841 0.799943403051277 0.799943403051277 0.799943403051277
Apoc1 ENSMUSG00000040564 0.4795309607329 0.862138720883195 0.599485743624143 0.862138720883195 0.862138720883195 0.862138720883195

Biosynthesis of cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coq6 ENSMUSG00000021235 0.202352369075743 0.202352369075743 0.00476879790864588 0.0143063937259376 0.101420611770647 0.152130917655971
Rgn ENSMUSG00000023070 0.657373786046955 0.707611446511957 0.66613887252376 0.707611446511957 0.707611446511957 0.707611446511957
Kynu ENSMUSG00000026866 0.977727420064452 0.99051026338415 0.99051026338415 0.99051026338415 0.857826543462636 0.99051026338415
Tdo2 ENSMUSG00000028011 0.426369423436919 0.5990459917723 0.47441542546469 0.5990459917723 0.5990459917723 0.5990459917723
Mpi ENSMUSG00000032306 0.862113402233359 0.862113402233359 0.767197551937537 0.862113402233359 0.613249211642643 0.862113402233359
Gulo ENSMUSG00000034450 0.354318856254938 0.815141973081422 0.923792695568754 0.923792695568754 0.543427982054281 0.815141973081422
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Gch1 ENSMUSG00000037580 0.710158148453647 0.710158148453647 0.332495446876071 0.710158148453647 0.516447590235188 0.710158148453647
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Cox10 ENSMUSG00000042148 0.506251214728852 0.751855495734691 0.081505776059439 0.244517328178317 0.751855495734691 0.751855495734691
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Ascorbate and aldarate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rgn ENSMUSG00000023070 0.657373786046955 0.707611446511957 0.66613887252376 0.707611446511957 0.707611446511957 0.707611446511957
Gulo ENSMUSG00000034450 0.354318856254938 0.815141973081422 0.923792695568754 0.923792695568754 0.543427982054281 0.815141973081422
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Pentose and glucuronate interconversions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dhdh ENSMUSG00000011382 0.779252522977749 0.779252522977749 0.773221801768075 0.779252522977749 0.564245404879385 0.779252522977749
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Cysteine and methionine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tat ENSMUSG00000001670 0.151362477657136 0.454087432971407 0.643003409026857 0.643003409026857 0.557814313289308 0.643003409026857
Adi1 ENSMUSG00000020629 0.376008097372252 0.464911672550297 0.0180877329853707 0.0542631989561121 0.464911672550297 0.464911672550297
Sds ENSMUSG00000029597 0.757630750935161 0.990426195060373 0.722291376566824 0.990426195060373 0.990426195060373 0.990426195060373
Ldhb ENSMUSG00000030246 0.930675665505726 0.930675665505726 0.858920702354651 0.930675665505726 0.707185278201982 0.930675665505726
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Ccbl2 ENSMUSG00000040213 0.748904577539404 0.748904577539404 0.556150395458649 0.748904577539404 0.745879617001619 0.748904577539404
Bhmt ENSMUSG00000074768 0.987220246262762 0.987373460396975 0.745754825898419 0.987373460396975 0.987373460396975 0.987373460396975

PPAR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Hmgcs2 ENSMUSG00000027875 0.189976511224712 0.569929533674135 0.652576611045286 0.710570408299713 0.710570408299713 0.710570408299713
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Me3 ENSMUSG00000030621 0.577434373307305 0.911885418272329 0.743025519839971 0.911885418272329 0.911885418272329 0.911885418272329
Slc27a1 ENSMUSG00000031808 0.259371516516941 0.514488019542028 0.514488019542028 0.514488019542028 0.50425112928588 0.514488019542028
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Apoc3 ENSMUSG00000032081 0.249260126876618 0.747780380629853 0.527409784444452 0.791114676666678 0.86515846438042 0.86515846438042
Scd1 ENSMUSG00000037071 0.627130562693556 0.993701875928424 0.993701875928424 0.993701875928424 0.728267379696892 0.993701875928424
Fabp1 ENSMUSG00000054422 0.974698871826828 0.974698871826828 0.908822299680013 0.974698871826828 0.751021115781529 0.974698871826828

Coronavirus disease - COVID-19

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
C4a ENSMUSG00000015451 0.690072349221893 0.855927494244339 0.855927494244339 0.855927494244339 0.837393384610836 0.855927494244339
Egfr ENSMUSG00000020122 0.419836425673643 0.577689230614226 0.577689230614226 0.577689230614226 0.358853980413935 0.577689230614226
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
C6 ENSMUSG00000022181 0.914593164198867 0.980887905229622 0.453633067649645 0.980887905229622 0.980887905229622 0.980887905229622
Masp1 ENSMUSG00000022887 0.569582207383391 0.937086821458048 0.803600869461786 0.937086821458048 0.937086821458048 0.937086821458048
Hbegf ENSMUSG00000024486 0.751915027147281 0.751915027147281 0.739683412148558 0.751915027147281 0.646335477901793 0.751915027147281
Hc ENSMUSG00000026874 0.924121232478127 0.924121232478127 0.849036562644297 0.924121232478127 0.880695899043171 0.924121232478127
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Masp2 ENSMUSG00000028979 0.971656010064839 0.971656010064839 0.577630409042643 0.971656010064839 0.815774120725749 0.971656010064839
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881

Porphyrin and chlorophyll metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cp ENSMUSG00000003617 0.791425971714697 0.806678815880941 0.806678815880941 0.806678815880941 0.722386381245228 0.806678815880941
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Cox10 ENSMUSG00000042148 0.506251214728852 0.751855495734691 0.081505776059439 0.244517328178317 0.751855495734691 0.751855495734691
Ugt2b5 ENSMUSG00000054630 0.544264667582795 0.894001622002822 0.894001622002822 0.894001622002822 0.737485889099215 0.894001622002822
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Ubiquinone and other terpenoid-quinone biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tat ENSMUSG00000001670 0.151362477657136 0.454087432971407 0.643003409026857 0.643003409026857 0.557814313289308 0.643003409026857
Coq6 ENSMUSG00000021235 0.202352369075743 0.202352369075743 0.00476879790864588 0.0143063937259376 0.101420611770647 0.152130917655971
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482

Formation of Fibrin Clot (Clotting Cascade)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F12 ENSMUSG00000021492 0.780292597460224 0.984089396276371 0.820417084796806 0.984089396276371 0.984089396276371 0.984089396276371
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cp ENSMUSG00000003617 0.791425971714697 0.806678815880941 0.806678815880941 0.806678815880941 0.722386381245228 0.806678815880941
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Igf1 ENSMUSG00000020053 0.142697333049043 0.42809199914713 0.384614086830781 0.561560252720873 0.561560252720873 0.561560252720873
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
Ahsg ENSMUSG00000022868 0.204974796248173 0.378040660348548 0.378040660348548 0.378040660348548 0.260772803521605 0.378040660348548
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Igfbp5 ENSMUSG00000026185 0.83739474521978 0.94022919988977 0.94022919988977 0.94022919988977 0.865243873372128 0.94022919988977
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Qsox1 ENSMUSG00000033684 0.577610030573926 0.577610030573926 0.231999797428305 0.499142233014472 0.332761488676314 0.499142233014472
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Lamb2 ENSMUSG00000052911 0.410690749650905 0.616036124476358 0.0907310861443944 0.272193258433183 0.803448030246651 0.803448030246651
Serpina10 ENSMUSG00000061947 0.681384066245969 0.90942111678249 0.531658995525716 0.90942111678249 0.90942111678249 0.90942111678249
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881

Post-translational protein phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cp ENSMUSG00000003617 0.791425971714697 0.806678815880941 0.806678815880941 0.806678815880941 0.722386381245228 0.806678815880941
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
Ahsg ENSMUSG00000022868 0.204974796248173 0.378040660348548 0.378040660348548 0.378040660348548 0.260772803521605 0.378040660348548
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Igfbp5 ENSMUSG00000026185 0.83739474521978 0.94022919988977 0.94022919988977 0.94022919988977 0.865243873372128 0.94022919988977
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Qsox1 ENSMUSG00000033684 0.577610030573926 0.577610030573926 0.231999797428305 0.499142233014472 0.332761488676314 0.499142233014472
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Lamb2 ENSMUSG00000052911 0.410690749650905 0.616036124476358 0.0907310861443944 0.272193258433183 0.803448030246651 0.803448030246651
Serpina10 ENSMUSG00000061947 0.681384066245969 0.90942111678249 0.531658995525716 0.90942111678249 0.90942111678249 0.90942111678249
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pemt ENSMUSG00000000301 0.761183182115839 0.981108783328759 0.469693086782545 0.981108783328759 0.981108783328759 0.981108783328759
Ftcd ENSMUSG00000001155 0.632321655854328 0.786163114393065 0.704172496637062 0.786163114393065 0.786163114393065 0.786163114393065
Tat ENSMUSG00000001670 0.151362477657136 0.454087432971407 0.643003409026857 0.643003409026857 0.557814313289308 0.643003409026857
Idh3g ENSMUSG00000002010 0.695598092746212 0.745911614681288 0.745911614681288 0.745911614681288 0.632642939869658 0.745911614681288
Psmc3 ENSMUSG00000002102 0.120248581855906 0.180372872783859 0.00409858469443962 0.0122957540833189 0.421672996985173 0.421672996985173
Cd320 ENSMUSG00000002308 0.599440127516376 0.865219010244715 0.865219010244715 0.865219010244715 0.862137379847626 0.865219010244715
Pon1 ENSMUSG00000002588 0.786526928452999 0.786526928452999 0.436119577688839 0.658185292289621 0.438790194859748 0.658185292289621
Gnmt ENSMUSG00000002769 0.516716224222671 0.571831376854682 0.571831376854682 0.571831376854682 0.292415180350565 0.571831376854682
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp17a1 ENSMUSG00000003555 0.389420562143718 0.406358017223015 0.181129646960049 0.406358017223015 0.406358017223015 0.406358017223015
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Hyal1 ENSMUSG00000010051 0.825077875461598 0.825077875461598 0.507000703324683 0.760501054987025 0.431746903053683 0.760501054987025
Amdhd1 ENSMUSG00000015890 0.742590574122166 0.742590574122166 0.549473333106631 0.742590574122166 0.637861074076197 0.742590574122166
Slc6a8 ENSMUSG00000019558 0.719421782664461 0.80666404347535 0.169426525960531 0.508279577881592 0.80666404347535 0.80666404347535
Arg1 ENSMUSG00000019987 0.291428895857939 0.874286687573818 0.958952177959993 0.958952177959993 0.659990777326478 0.958952177959993
Hal ENSMUSG00000020017 0.663138111797486 0.663138111797486 0.552623819540299 0.663138111797486 0.378376707153874 0.663138111797486
Gamt ENSMUSG00000020150 0.221430590061347 0.33214588509202 0.0486822048248833 0.14604661447465 0.596700979953383 0.596700979953383
Adi1 ENSMUSG00000020629 0.376008097372252 0.464911672550297 0.0180877329853707 0.0542631989561121 0.464911672550297 0.464911672550297
Pygl ENSMUSG00000021069 0.467328931734958 0.644095199602022 0.644095199602022 0.644095199602022 0.524829229050038 0.644095199602022
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Isca2 ENSMUSG00000021241 0.438118925695957 0.786918761611165 0.524612507740777 0.786918761611165 0.924467519278001 0.924467519278001
Elovl2 ENSMUSG00000021364 0.911758016272639 0.911758016272639 0.778762754215036 0.911758016272639 0.710227553933736 0.911758016272639
Oxct1 ENSMUSG00000022186 0.0752796906043998 0.225839071813199 0.78833637711065 0.91511665827977 0.91511665827977 0.91511665827977
Tymp ENSMUSG00000022615 0.0892663146705974 0.267798944011792 0.344421448552506 0.516632172828759 0.949571322507187 0.949571322507187
Cox14 ENSMUSG00000023020 0.32038986554853 0.480584798322796 0.196549809598803 0.480584798322796 0.761056573115645 0.761056573115645
Glo1 ENSMUSG00000024026 0.669809139782919 0.749174714108576 0.319055685172727 0.749174714108576 0.749174714108576 0.749174714108576
Rbp4 ENSMUSG00000024990 0.303826275958889 0.472927186948364 0.710554937413083 0.710554937413083 0.315284791298909 0.472927186948364
Acot9 ENSMUSG00000025287 0.974807686976734 0.974807686976734 0.740190266120286 0.974807686976734 0.501901325181496 0.974807686976734
Car5a ENSMUSG00000025317 0.411667270479958 0.883522439262698 0.883522439262698 0.883522439262698 0.747324037409172 0.883522439262698
Paox ENSMUSG00000025464 0.655402386497108 0.983103579745663 0.397353958253998 0.983103579745663 0.996848608819353 0.996848608819353
Marc1 ENSMUSG00000026621 0.241117401709319 0.361676102563978 0.229361918691526 0.361676102563978 0.649338955766246 0.649338955766246
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Pdss1 ENSMUSG00000026784 0.981108464903076 0.996851199017196 0.85903958732912 0.996851199017196 0.996851199017196 0.996851199017196
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Hao1 ENSMUSG00000027261 0.95416040513411 0.95416040513411 0.928131198252319 0.95416040513411 0.229373904811969 0.688121714435906
Acss1 ENSMUSG00000027452 0.852824011763922 0.852824011763922 0.334788274939822 0.852824011763922 0.687181916981449 0.852824011763922
Hmgcs2 ENSMUSG00000027875 0.189976511224712 0.569929533674135 0.652576611045286 0.710570408299713 0.710570408299713 0.710570408299713
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Tdo2 ENSMUSG00000028011 0.426369423436919 0.5990459917723 0.47441542546469 0.5990459917723 0.5990459917723 0.5990459917723
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Sds ENSMUSG00000029597 0.757630750935161 0.990426195060373 0.722291376566824 0.990426195060373 0.990426195060373 0.990426195060373
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Ldhb ENSMUSG00000030246 0.930675665505726 0.930675665505726 0.858920702354651 0.930675665505726 0.707185278201982 0.930675665505726
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Me3 ENSMUSG00000030621 0.577434373307305 0.911885418272329 0.743025519839971 0.911885418272329 0.911885418272329 0.911885418272329
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Slco2b1 ENSMUSG00000030737 0.0800980948095627 0.120147142214344 0.135129376639027 0.135129376639027 0.06839451137241 0.120147142214344
Bckdk ENSMUSG00000030802 0.311322015432919 0.466983023149378 0.27844880406173 0.466983023149378 0.577610030573926 0.577610030573926
Gnpat ENSMUSG00000031985 0.722355192412903 0.722355192412903 0.431674698818024 0.722355192412903 0.596747006562616 0.722355192412903
Nnmt ENSMUSG00000032271 0.476576588548111 0.476576588548111 0.358473663313352 0.476576588548111 0.217949184221594 0.476576588548111
Idh3a ENSMUSG00000032279 0.464642363777259 0.87138171210917 0.701795742495507 0.87138171210917 0.87138171210917 0.87138171210917
Hsd17b13 ENSMUSG00000034528 0.600021392952413 0.600021392952413 0.17663573059565 0.4148740861618 0.276582724107866 0.4148740861618
Gc ENSMUSG00000035540 0.103801978664016 0.311405935992049 0.282024042280797 0.423036063421196 0.440485200286939 0.440485200286939
Thrsp ENSMUSG00000035686 0.908854129616767 0.946501420881211 0.354905116570767 0.946501420881211 0.946501420881211 0.946501420881211
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Scd1 ENSMUSG00000037071 0.627130562693556 0.993701875928424 0.993701875928424 0.993701875928424 0.728267379696892 0.993701875928424
Gch1 ENSMUSG00000037580 0.710158148453647 0.710158148453647 0.332495446876071 0.710158148453647 0.516447590235188 0.710158148453647
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Elovl3 ENSMUSG00000038754 0.782935775862553 0.851777667560445 0.851777667560445 0.851777667560445 0.653560408657682 0.851777667560445
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Sgms1 ENSMUSG00000040451 0.452748404705691 0.679122607058537 0.933927805028281 0.933927805028281 0.334611881225443 0.679122607058537
Agmat ENSMUSG00000040706 0.874315257799446 0.927403291801747 0.115556678094432 0.346670034283297 0.927403291801747 0.927403291801747
Slc19a2 ENSMUSG00000040918 0.974809211474832 0.974809211474832 0.675492665583746 0.974809211474832 0.66113662230505 0.974809211474832
Bbox1 ENSMUSG00000041660 0.641458628512556 0.84873787883349 0.84873787883349 0.84873787883349 0.614398935341444 0.84873787883349
Cox10 ENSMUSG00000042148 0.506251214728852 0.751855495734691 0.081505776059439 0.244517328178317 0.751855495734691 0.751855495734691
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437
Cyp2f2 ENSMUSG00000052974 0.49161741983438 0.955068462470323 0.636712308313548 0.955068462470323 0.990512657507331 0.990512657507331
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Fabp1 ENSMUSG00000054422 0.974698871826828 0.974698871826828 0.908822299680013 0.974698871826828 0.751021115781529 0.974698871826828
Atp5s ENSMUSG00000054894 0.952783943377857 0.952783943377857 0.758087843772188 0.952783943377857 0.862110596660107 0.952783943377857
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663
Ttr ENSMUSG00000061808 0.612871622305501 0.95268277235846 0.704327152799491 0.95268277235846 0.95268277235846 0.95268277235846
Ces3a ENSMUSG00000069922 0.350921972704152 0.790945866417902 0.607234665668771 0.790945866417902 0.790945866417902 0.790945866417902
Hs3st3b1 ENSMUSG00000070407 0.959082919743208 0.981107015968348 0.981107015968348 0.981107015968348 0.849730399229309 0.981107015968348
Etnk2 ENSMUSG00000070644 0.846608146393741 0.846608146393741 0.245702708267281 0.737108124801842 0.590751046168787 0.846608146393741
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774
Ttpa ENSMUSG00000073988 0.821933800168012 0.949635284957978 0.767200051709053 0.949635284957978 0.949635284957978 0.949635284957978
Bhmt ENSMUSG00000074768 0.987220246262762 0.987373460396975 0.745754825898419 0.987373460396975 0.987373460396975 0.987373460396975
Sco2 ENSMUSG00000091780 0.899477994339459 0.899477994339459 0.00534654377250966 0.016039631317529 0.123068814201984 0.184603221302976

Platelet degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoh ENSMUSG00000000049 0.943315964359844 0.943315964359844 0.629805577436838 0.943315964359844 0.635532027271455 0.943315964359844
Igf1 ENSMUSG00000020053 0.142697333049043 0.42809199914713 0.384614086830781 0.561560252720873 0.561560252720873 0.561560252720873
Itih4 ENSMUSG00000021922 0.759320130352583 0.924433977689949 0.795855234500013 0.924433977689949 0.924433977689949 0.924433977689949
Ahsg ENSMUSG00000022868 0.204974796248173 0.378040660348548 0.378040660348548 0.378040660348548 0.260772803521605 0.378040660348548
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Cd63 ENSMUSG00000025351 0.865216296528728 0.977961621197461 0.977961621197461 0.977961621197461 0.846621244927785 0.977961621197461
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Qsox1 ENSMUSG00000033684 0.577610030573926 0.577610030573926 0.231999797428305 0.499142233014472 0.332761488676314 0.499142233014472
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Orm1 ENSMUSG00000039196 0.694041038662893 0.694041038662893 0.362683493319123 0.544025239978684 0.155003655407011 0.465010966221033
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Phactr2 ENSMUSG00000062866 0.464686418082273 0.81278436789464 0.81278436789464 0.81278436789464 0.770070426897836 0.81278436789464

Terminal pathway of complement

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
C6 ENSMUSG00000022181 0.914593164198867 0.980887905229622 0.453633067649645 0.980887905229622 0.980887905229622 0.980887905229622
Hc ENSMUSG00000026874 0.924121232478127 0.924121232478127 0.849036562644297 0.924121232478127 0.880695899043171 0.924121232478127
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594

Response to elevated platelet cytosolic Ca2+

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoh ENSMUSG00000000049 0.943315964359844 0.943315964359844 0.629805577436838 0.943315964359844 0.635532027271455 0.943315964359844
Igf1 ENSMUSG00000020053 0.142697333049043 0.42809199914713 0.384614086830781 0.561560252720873 0.561560252720873 0.561560252720873
Itih4 ENSMUSG00000021922 0.759320130352583 0.924433977689949 0.795855234500013 0.924433977689949 0.924433977689949 0.924433977689949
Ahsg ENSMUSG00000022868 0.204974796248173 0.378040660348548 0.378040660348548 0.378040660348548 0.260772803521605 0.378040660348548
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Cd63 ENSMUSG00000025351 0.865216296528728 0.977961621197461 0.977961621197461 0.977961621197461 0.846621244927785 0.977961621197461
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Qsox1 ENSMUSG00000033684 0.577610030573926 0.577610030573926 0.231999797428305 0.499142233014472 0.332761488676314 0.499142233014472
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Orm1 ENSMUSG00000039196 0.694041038662893 0.694041038662893 0.362683493319123 0.544025239978684 0.155003655407011 0.465010966221033
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Phactr2 ENSMUSG00000062866 0.464686418082273 0.81278436789464 0.81278436789464 0.81278436789464 0.770070426897836 0.81278436789464

Gamma-carboxylation of protein precursors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Proz ENSMUSG00000031445 0.993534077423747 0.993534077423747 0.865615448192715 0.993534077423747 0.9904138938224 0.993534077423747
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482

Common Pathway of Fibrin Clot Formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Proz ENSMUSG00000031445 0.993534077423747 0.993534077423747 0.865615448192715 0.993534077423747 0.9904138938224 0.993534077423747
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482

Biological oxidations

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Paox ENSMUSG00000025464 0.655402386497108 0.983103579745663 0.397353958253998 0.983103579745663 0.996848608819353 0.996848608819353
Marc1 ENSMUSG00000026621 0.241117401709319 0.361676102563978 0.229361918691526 0.361676102563978 0.649338955766246 0.649338955766246
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Acss1 ENSMUSG00000027452 0.852824011763922 0.852824011763922 0.334788274939822 0.852824011763922 0.687181916981449 0.852824011763922
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Nnmt ENSMUSG00000032271 0.476576588548111 0.476576588548111 0.358473663313352 0.476576588548111 0.217949184221594 0.476576588548111
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Cyp2f2 ENSMUSG00000052974 0.49161741983438 0.955068462470323 0.636712308313548 0.955068462470323 0.990512657507331 0.990512657507331
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412
Ces3a ENSMUSG00000069922 0.350921972704152 0.790945866417902 0.607234665668771 0.790945866417902 0.790945866417902 0.790945866417902
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Intrinsic Pathway of Fibrin Clot Formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F12 ENSMUSG00000021492 0.780292597460224 0.984089396276371 0.820417084796806 0.984089396276371 0.984089396276371 0.984089396276371
Serpind1 ENSMUSG00000022766 0.666419779092279 0.981078089985185 0.981078089985185 0.981078089985185 0.749062638163311 0.981078089985185
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Serpinc1 ENSMUSG00000026715 0.8125414008359 0.823062645010834 0.823062645010834 0.823062645010834 0.778482886160294 0.823062645010834
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241

Recycling of bile acids and salts

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Proz ENSMUSG00000031445 0.993534077423747 0.993534077423747 0.865615448192715 0.993534077423747 0.9904138938224 0.993534077423747

Removal of aminoterminal propeptides from gamma-carboxylated proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Proz ENSMUSG00000031445 0.993534077423747 0.993534077423747 0.865615448192715 0.993534077423747 0.9904138938224 0.993534077423747

Complement cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
C6 ENSMUSG00000022181 0.914593164198867 0.980887905229622 0.453633067649645 0.980887905229622 0.980887905229622 0.980887905229622
Masp1 ENSMUSG00000022887 0.569582207383391 0.937086821458048 0.803600869461786 0.937086821458048 0.937086821458048 0.937086821458048
Cpn2 ENSMUSG00000023176 0.0332789281354689 0.0998367844064068 0.823153166376975 0.823153166376975 0.456318844513912 0.684478266770868
Hc ENSMUSG00000026874 0.924121232478127 0.924121232478127 0.849036562644297 0.924121232478127 0.880695899043171 0.924121232478127
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Masp2 ENSMUSG00000028979 0.971656010064839 0.971656010064839 0.577630409042643 0.971656010064839 0.815774120725749 0.971656010064839
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594
Crp ENSMUSG00000037942 0.929781728360558 0.929781728360558 0.387391702498236 0.647855359966271 0.431903573310847 0.647855359966271
Cfi ENSMUSG00000058952 0.600963382222105 0.882365843940303 0.814857240977372 0.882365843940303 0.882365843940303 0.882365843940303
Gm4788 ENSMUSG00000070594 0.619541502920014 0.619541502920014 0.412259683579774 0.619541502920014 0.444002627147544 0.619541502920014
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881

Bile acid and bile salt metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437

Non-integrin membrane-ECM interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
Col5a2 ENSMUSG00000026042 0.880694707297781 0.880694707297781 0.452530478701461 0.678795718052192 0.361252130416552 0.678795718052192
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Ddr2 ENSMUSG00000026674 0.794379187946448 0.794379187946448 0.681329201816715 0.794379187946448 0.438569552058968 0.794379187946448
Itga6 ENSMUSG00000027111 0.85903634786436 0.896378668785114 0.896378668785114 0.896378668785114 0.713538815010198 0.896378668785114
Col4a1 ENSMUSG00000031502 0.827618285628854 0.827618285628854 0.0445234387141291 0.133570316142387 0.604046364232818 0.827618285628854
Ttr ENSMUSG00000061808 0.612871622305501 0.95268277235846 0.704327152799491 0.95268277235846 0.95268277235846 0.95268277235846

Plasma lipoprotein assembly, remodeling, and clearance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Angptl3 ENSMUSG00000028553 0.965163649621279 0.965163649621279 0.244817865150009 0.37623230233663 0.250821534891086 0.37623230233663
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Lipc ENSMUSG00000032207 0.775011478313671 0.799943403051277 0.674420969809841 0.799943403051277 0.799943403051277 0.799943403051277
Apoc1 ENSMUSG00000040564 0.4795309607329 0.862138720883195 0.599485743624143 0.862138720883195 0.862138720883195 0.862138720883195
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Ces3a ENSMUSG00000069922 0.350921972704152 0.790945866417902 0.607234665668771 0.790945866417902 0.790945866417902 0.790945866417902
Apoc4 ENSMUSG00000074336 0.987273119643355 0.987273119643355 0.94276155351988 0.987273119643355 0.201877311362099 0.605631934086298

Metabolism of amino acids and derivatives

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ftcd ENSMUSG00000001155 0.632321655854328 0.786163114393065 0.704172496637062 0.786163114393065 0.786163114393065 0.786163114393065
Tat ENSMUSG00000001670 0.151362477657136 0.454087432971407 0.643003409026857 0.643003409026857 0.557814313289308 0.643003409026857
Psmc3 ENSMUSG00000002102 0.120248581855906 0.180372872783859 0.00409858469443962 0.0122957540833189 0.421672996985173 0.421672996985173
Gnmt ENSMUSG00000002769 0.516716224222671 0.571831376854682 0.571831376854682 0.571831376854682 0.292415180350565 0.571831376854682
Amdhd1 ENSMUSG00000015890 0.742590574122166 0.742590574122166 0.549473333106631 0.742590574122166 0.637861074076197 0.742590574122166
Slc6a8 ENSMUSG00000019558 0.719421782664461 0.80666404347535 0.169426525960531 0.508279577881592 0.80666404347535 0.80666404347535
Arg1 ENSMUSG00000019987 0.291428895857939 0.874286687573818 0.958952177959993 0.958952177959993 0.659990777326478 0.958952177959993
Hal ENSMUSG00000020017 0.663138111797486 0.663138111797486 0.552623819540299 0.663138111797486 0.378376707153874 0.663138111797486
Gamt ENSMUSG00000020150 0.221430590061347 0.33214588509202 0.0486822048248833 0.14604661447465 0.596700979953383 0.596700979953383
Adi1 ENSMUSG00000020629 0.376008097372252 0.464911672550297 0.0180877329853707 0.0542631989561121 0.464911672550297 0.464911672550297
Paox ENSMUSG00000025464 0.655402386497108 0.983103579745663 0.397353958253998 0.983103579745663 0.996848608819353 0.996848608819353
Hao1 ENSMUSG00000027261 0.95416040513411 0.95416040513411 0.928131198252319 0.95416040513411 0.229373904811969 0.688121714435906
Tdo2 ENSMUSG00000028011 0.426369423436919 0.5990459917723 0.47441542546469 0.5990459917723 0.5990459917723 0.5990459917723
Sds ENSMUSG00000029597 0.757630750935161 0.990426195060373 0.722291376566824 0.990426195060373 0.990426195060373 0.990426195060373
Bckdk ENSMUSG00000030802 0.311322015432919 0.466983023149378 0.27844880406173 0.466983023149378 0.577610030573926 0.577610030573926
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Agmat ENSMUSG00000040706 0.874315257799446 0.927403291801747 0.115556678094432 0.346670034283297 0.927403291801747 0.927403291801747
Bbox1 ENSMUSG00000041660 0.641458628512556 0.84873787883349 0.84873787883349 0.84873787883349 0.614398935341444 0.84873787883349
Bhmt ENSMUSG00000074768 0.987220246262762 0.987373460396975 0.745754825898419 0.987373460396975 0.987373460396975 0.987373460396975

Phase I - Functionalization of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Paox ENSMUSG00000025464 0.655402386497108 0.983103579745663 0.397353958253998 0.983103579745663 0.996848608819353 0.996848608819353
Marc1 ENSMUSG00000026621 0.241117401709319 0.361676102563978 0.229361918691526 0.361676102563978 0.649338955766246 0.649338955766246
Acss1 ENSMUSG00000027452 0.852824011763922 0.852824011763922 0.334788274939822 0.852824011763922 0.687181916981449 0.852824011763922
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Ephx1 ENSMUSG00000038776 0.927649520976282 0.927649520976282 0.371661096445603 0.557491644668405 0.168163222566058 0.504489667698174
Cyp2f2 ENSMUSG00000052974 0.49161741983438 0.955068462470323 0.636712308313548 0.955068462470323 0.990512657507331 0.990512657507331
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991
Cyp3a11 ENSMUSG00000056035 0.344434981429902 0.936002321747312 0.936002321747312 0.936002321747312 0.792923895669752 0.936002321747312
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412
Ces3a ENSMUSG00000069922 0.350921972704152 0.790945866417902 0.607234665668771 0.790945866417902 0.790945866417902 0.790945866417902

Plasma lipoprotein remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Angptl3 ENSMUSG00000028553 0.965163649621279 0.965163649621279 0.244817865150009 0.37623230233663 0.250821534891086 0.37623230233663
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Lipc ENSMUSG00000032207 0.775011478313671 0.799943403051277 0.674420969809841 0.799943403051277 0.799943403051277 0.799943403051277
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364

Extrinsic Pathway of Fibrin Clot Formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241

Metabolism of steroids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp17a1 ENSMUSG00000003555 0.389420562143718 0.406358017223015 0.181129646960049 0.406358017223015 0.406358017223015 0.406358017223015
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Gc ENSMUSG00000035540 0.103801978664016 0.311405935992049 0.282024042280797 0.423036063421196 0.440485200286939 0.440485200286939
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663

Mitochondrial translation elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl45 ENSMUSG00000018882 0.203490367929184 0.305235551893776 2.50991447387533e-05 7.52974342162599e-05 0.336126301373614 0.336126301373614
Mrpl11 ENSMUSG00000024902 0.149345409445956 0.448036228337867 0.713473187040387 0.713473187040387 0.34263669044236 0.51395503566354
Mrpl37 ENSMUSG00000028622 0.442860379239153 0.664290568858729 0.000491708236582808 0.00147512470974843 0.924466971709381 0.924466971709381
Mrps15 ENSMUSG00000028861 0.607664533164001 0.607664533164001 0.168107261774871 0.314343883151662 0.209562588767774 0.314343883151662
Mrps33 ENSMUSG00000029918 0.125046128602933 0.1875691929044 0.0555098654220019 0.166529596266006 0.49188556518969 0.49188556518969
Mrpl46 ENSMUSG00000030612 0.491808150526425 0.59115853757548 0.175640955365322 0.526922866095966 0.59115853757548 0.59115853757548
Mrpl47 ENSMUSG00000037531 0.899459493011869 0.899459493011869 0.162035882748993 0.486107648246978 0.770086918232864 0.899459493011869
Mrpl35 ENSMUSG00000052962 0.294667377135803 0.442001065703705 0.812792576184396 0.812792576184396 0.283858110324802 0.442001065703705
Mrps9 ENSMUSG00000060679 0.740160970934768 0.761169449129895 0.269713442307116 0.761169449129895 0.761169449129895 0.761169449129895
Mrps36 ENSMUSG00000061474 0.698735912530332 0.698735912530332 0.276594223847887 0.532507649338445 0.355005099558963 0.532507649338445

Mitochondrial translation termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl45 ENSMUSG00000018882 0.203490367929184 0.305235551893776 2.50991447387533e-05 7.52974342162599e-05 0.336126301373614 0.336126301373614
Mrpl11 ENSMUSG00000024902 0.149345409445956 0.448036228337867 0.713473187040387 0.713473187040387 0.34263669044236 0.51395503566354
Mrpl37 ENSMUSG00000028622 0.442860379239153 0.664290568858729 0.000491708236582808 0.00147512470974843 0.924466971709381 0.924466971709381
Mrps15 ENSMUSG00000028861 0.607664533164001 0.607664533164001 0.168107261774871 0.314343883151662 0.209562588767774 0.314343883151662
Mrps33 ENSMUSG00000029918 0.125046128602933 0.1875691929044 0.0555098654220019 0.166529596266006 0.49188556518969 0.49188556518969
Mrpl46 ENSMUSG00000030612 0.491808150526425 0.59115853757548 0.175640955365322 0.526922866095966 0.59115853757548 0.59115853757548
Mrpl47 ENSMUSG00000037531 0.899459493011869 0.899459493011869 0.162035882748993 0.486107648246978 0.770086918232864 0.899459493011869
Mrpl35 ENSMUSG00000052962 0.294667377135803 0.442001065703705 0.812792576184396 0.812792576184396 0.283858110324802 0.442001065703705
Mrps9 ENSMUSG00000060679 0.740160970934768 0.761169449129895 0.269713442307116 0.761169449129895 0.761169449129895 0.761169449129895
Mrps36 ENSMUSG00000061474 0.698735912530332 0.698735912530332 0.276594223847887 0.532507649338445 0.355005099558963 0.532507649338445

Mitochondrial translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl45 ENSMUSG00000018882 0.203490367929184 0.305235551893776 2.50991447387533e-05 7.52974342162599e-05 0.336126301373614 0.336126301373614
Mrpl11 ENSMUSG00000024902 0.149345409445956 0.448036228337867 0.713473187040387 0.713473187040387 0.34263669044236 0.51395503566354
Mrpl37 ENSMUSG00000028622 0.442860379239153 0.664290568858729 0.000491708236582808 0.00147512470974843 0.924466971709381 0.924466971709381
Mrps15 ENSMUSG00000028861 0.607664533164001 0.607664533164001 0.168107261774871 0.314343883151662 0.209562588767774 0.314343883151662
Mrps33 ENSMUSG00000029918 0.125046128602933 0.1875691929044 0.0555098654220019 0.166529596266006 0.49188556518969 0.49188556518969
Mrpl46 ENSMUSG00000030612 0.491808150526425 0.59115853757548 0.175640955365322 0.526922866095966 0.59115853757548 0.59115853757548
Mrpl47 ENSMUSG00000037531 0.899459493011869 0.899459493011869 0.162035882748993 0.486107648246978 0.770086918232864 0.899459493011869
Mrpl35 ENSMUSG00000052962 0.294667377135803 0.442001065703705 0.812792576184396 0.812792576184396 0.283858110324802 0.442001065703705
Mrps9 ENSMUSG00000060679 0.740160970934768 0.761169449129895 0.269713442307116 0.761169449129895 0.761169449129895 0.761169449129895
Mrps36 ENSMUSG00000061474 0.698735912530332 0.698735912530332 0.276594223847887 0.532507649338445 0.355005099558963 0.532507649338445

Platelet activation, signaling and aggregation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoh ENSMUSG00000000049 0.943315964359844 0.943315964359844 0.629805577436838 0.943315964359844 0.635532027271455 0.943315964359844
Igf1 ENSMUSG00000020053 0.142697333049043 0.42809199914713 0.384614086830781 0.561560252720873 0.561560252720873 0.561560252720873
Itih4 ENSMUSG00000021922 0.759320130352583 0.924433977689949 0.795855234500013 0.924433977689949 0.924433977689949 0.924433977689949
Ahsg ENSMUSG00000022868 0.204974796248173 0.378040660348548 0.378040660348548 0.378040660348548 0.260772803521605 0.378040660348548
Kng1 ENSMUSG00000022875 0.248276503418428 0.372414755127642 0.174799583136815 0.372414755127642 0.483245976170612 0.483245976170612
Cd63 ENSMUSG00000025351 0.865216296528728 0.977961621197461 0.977961621197461 0.977961621197461 0.846621244927785 0.977961621197461
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F5 ENSMUSG00000026579 0.538956446412857 0.874634894650761 0.58812520780372 0.874634894650761 0.874634894650761 0.874634894650761
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Qsox1 ENSMUSG00000033684 0.577610030573926 0.577610030573926 0.231999797428305 0.499142233014472 0.332761488676314 0.499142233014472
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Orm1 ENSMUSG00000039196 0.694041038662893 0.694041038662893 0.362683493319123 0.544025239978684 0.155003655407011 0.465010966221033
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Phactr2 ENSMUSG00000062866 0.464686418082273 0.81278436789464 0.81278436789464 0.81278436789464 0.770070426897836 0.81278436789464

Transport of organic anions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slco3a1 ENSMUSG00000025790 0.59396335859363 0.767153830798494 0.259609045653319 0.767153830798494 0.767153830798494 0.767153830798494
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slco2b1 ENSMUSG00000030737 0.0800980948095627 0.120147142214344 0.135129376639027 0.135129376639027 0.06839451137241 0.120147142214344

Histidine catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ftcd ENSMUSG00000001155 0.632321655854328 0.786163114393065 0.704172496637062 0.786163114393065 0.786163114393065 0.786163114393065
Amdhd1 ENSMUSG00000015890 0.742590574122166 0.742590574122166 0.549473333106631 0.742590574122166 0.637861074076197 0.742590574122166
Hal ENSMUSG00000020017 0.663138111797486 0.663138111797486 0.552623819540299 0.663138111797486 0.378376707153874 0.663138111797486

Gamma carboxylation, hypusine formation and arylsulfatase activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
F9 ENSMUSG00000031138 0.650438755496679 0.650438755496679 0.602577888255526 0.650438755496679 0.540129285412182 0.650438755496679
F7 ENSMUSG00000031443 0.772880118425727 0.830965548387574 0.830965548387574 0.830965548387574 0.419263620983654 0.830965548387574
F10 ENSMUSG00000031444 0.544764441066161 0.817146661599241 0.949565161699704 0.949565161699704 0.288363327789257 0.817146661599241
Proz ENSMUSG00000031445 0.993534077423747 0.993534077423747 0.865615448192715 0.993534077423747 0.9904138938224 0.993534077423747
Ggcx ENSMUSG00000053460 0.566726710410317 0.710573959151482 0.663963470439382 0.710573959151482 0.710573959151482 0.710573959151482

Regulation of Complement cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C8g ENSMUSG00000015083 0.32021294856673 0.445389949121004 0.445389949121004 0.445389949121004 0.324627814239397 0.445389949121004
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
C9 ENSMUSG00000022149 0.889241472188613 0.889241472188613 0.69624393589919 0.889241472188613 0.717795301421764 0.889241472188613
C6 ENSMUSG00000022181 0.914593164198867 0.980887905229622 0.453633067649645 0.980887905229622 0.980887905229622 0.980887905229622
Cpn2 ENSMUSG00000023176 0.0332789281354689 0.0998367844064068 0.823153166376975 0.823153166376975 0.456318844513912 0.684478266770868
Hc ENSMUSG00000026874 0.924121232478127 0.924121232478127 0.849036562644297 0.924121232478127 0.880695899043171 0.924121232478127
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
C8b ENSMUSG00000029656 0.605302238623302 0.907953357934954 0.150823087413177 0.45246926223953 0.923444754909688 0.923444754909688
C8a ENSMUSG00000035031 0.658037570007594 0.658037570007594 0.373806157148447 0.658037570007594 0.505907892136346 0.658037570007594
Cfi ENSMUSG00000058952 0.600963382222105 0.882365843940303 0.814857240977372 0.882365843940303 0.882365843940303 0.882365843940303
Gm4788 ENSMUSG00000070594 0.619541502920014 0.619541502920014 0.412259683579774 0.619541502920014 0.444002627147544 0.619541502920014
C4b ENSMUSG00000073418 0.649829686173648 0.921400682033881 0.921400682033881 0.921400682033881 0.65550501101122 0.921400682033881

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437

p130Cas linkage to MAPK signaling for integrins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

GRB2:SOS provides linkage to MAPK signaling for Integrins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Heme degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slco2b1 ENSMUSG00000030737 0.0800980948095627 0.120147142214344 0.135129376639027 0.135129376639027 0.06839451137241 0.120147142214344
Fabp1 ENSMUSG00000054422 0.974698871826828 0.974698871826828 0.908822299680013 0.974698871826828 0.751021115781529 0.974698871826828

Integrin cell surface interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
Col5a2 ENSMUSG00000026042 0.880694707297781 0.880694707297781 0.452530478701461 0.678795718052192 0.361252130416552 0.678795718052192
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Itga6 ENSMUSG00000027111 0.85903634786436 0.896378668785114 0.896378668785114 0.896378668785114 0.713538815010198 0.896378668785114
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Col4a1 ENSMUSG00000031502 0.827618285628854 0.827618285628854 0.0445234387141291 0.133570316142387 0.604046364232818 0.827618285628854
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Metabolism of porphyrins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slco2b1 ENSMUSG00000030737 0.0800980948095627 0.120147142214344 0.135129376639027 0.135129376639027 0.06839451137241 0.120147142214344
Cox10 ENSMUSG00000042148 0.506251214728852 0.751855495734691 0.081505776059439 0.244517328178317 0.751855495734691 0.751855495734691
Fabp1 ENSMUSG00000054422 0.974698871826828 0.974698871826828 0.908822299680013 0.974698871826828 0.751021115781529 0.974698871826828

Regulation of TLR by endogenous ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lbp ENSMUSG00000016024 0.874358493085577 0.874358493085577 0.599078198721934 0.874358493085577 0.846528823550566 0.874358493085577
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Phase II - Conjugation of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mgst1 ENSMUSG00000008540 0.812804845564549 0.812804845564549 0.80056011138151 0.812804845564549 0.627223459025834 0.812804845564549
Mgst3 ENSMUSG00000026688 0.613293041323586 0.690086007050488 0.690086007050488 0.690086007050488 0.630036193481627 0.690086007050488
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Nnmt ENSMUSG00000032271 0.476576588548111 0.476576588548111 0.358473663313352 0.476576588548111 0.217949184221594 0.476576588548111
Ugt2a3 ENSMUSG00000035780 0.77177962362523 0.896953659610867 0.896953659610867 0.896953659610867 0.871299964325551 0.896953659610867
Ugt2b1 ENSMUSG00000035836 0.380999726029262 0.703365940550562 0.622622736539416 0.703365940550562 0.703365940550562 0.703365940550562
Mat1a ENSMUSG00000037798 0.735126750519657 0.735126750519657 0.30476543396931 0.735126750519657 0.553558477874177 0.735126750519657
Gstp1 ENSMUSG00000060803 0.0674174487976676 0.101126173196501 0.00257621230419526 0.00772863691258579 0.893041658799246 0.893041658799246
Ugt2b36 ENSMUSG00000070704 0.740836809647521 0.891895079423774 0.868622326708863 0.891895079423774 0.891895079423774 0.891895079423774

Transport of small molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmc3 ENSMUSG00000002102 0.120248581855906 0.180372872783859 0.00409858469443962 0.0122957540833189 0.421672996985173 0.421672996985173
Cp ENSMUSG00000003617 0.791425971714697 0.806678815880941 0.806678815880941 0.806678815880941 0.722386381245228 0.806678815880941
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Atp7b ENSMUSG00000006567 0.736904570625731 0.949604474210527 0.229999873494332 0.689999620482997 0.949604474210527 0.949604474210527
Slc17a8 ENSMUSG00000019935 0.729483100997625 0.905727726614082 0.905727726614082 0.905727726614082 0.854942943536616 0.905727726614082
Sgk1 ENSMUSG00000019970 2.30034220814283e-07 6.90102662442848e-07 0.852835206415765 0.852835206415765 0.481997815283758 0.722996722925636
Tfrc ENSMUSG00000022797 0.629693425046108 0.634627382957881 0.126167054955929 0.378501164867786 0.634627382957881 0.634627382957881
Slc29a1 ENSMUSG00000023942 0.704622961717071 0.704622961717071 0.262842557675966 0.583206066994738 0.388804044663159 0.583206066994738
Slco3a1 ENSMUSG00000025790 0.59396335859363 0.767153830798494 0.259609045653319 0.767153830798494 0.767153830798494 0.767153830798494
Angptl3 ENSMUSG00000028553 0.965163649621279 0.965163649621279 0.244817865150009 0.37623230233663 0.250821534891086 0.37623230233663
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Tfr2 ENSMUSG00000029716 0.514704685065481 0.965185298945677 0.736765475229494 0.965185298945677 0.965185298945677 0.965185298945677
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slco2b1 ENSMUSG00000030737 0.0800980948095627 0.120147142214344 0.135129376639027 0.135129376639027 0.06839451137241 0.120147142214344
Aqp8 ENSMUSG00000030762 0.350246506834888 0.350246506834888 0.191087507965486 0.350246506834888 0.276228338155824 0.350246506834888
Slc7a2 ENSMUSG00000031596 0.719442672867782 0.719442672867782 0.386329550937638 0.719442672867782 0.658083345504813 0.719442672867782
Slc25a4 ENSMUSG00000031633 0.837304602722345 0.905695529994224 0.905695529994224 0.905695529994224 0.794467121304791 0.905695529994224
Slc27a1 ENSMUSG00000031808 0.259371516516941 0.514488019542028 0.514488019542028 0.514488019542028 0.50425112928588 0.514488019542028
Apoa5 ENSMUSG00000032079 0.0980203633099947 0.294061089929984 0.524698020168901 0.572395335346079 0.572395335346079 0.572395335346079
Aqp9 ENSMUSG00000032204 0.568710953423365 0.683960988228502 0.683960988228502 0.683960988228502 0.401336329005836 0.683960988228502
Lipc ENSMUSG00000032207 0.775011478313671 0.799943403051277 0.674420969809841 0.799943403051277 0.799943403051277 0.799943403051277
Trf ENSMUSG00000032554 0.424803717403427 0.637205576105141 0.216943138697509 0.637205576105141 0.87767571705924 0.87767571705924
Atp6v1g1 ENSMUSG00000039105 0.739905344599766 0.996847787027275 0.424716839813708 0.996847787027275 0.996847787027275 0.996847787027275
Apoc1 ENSMUSG00000040564 0.4795309607329 0.862138720883195 0.599485743624143 0.862138720883195 0.862138720883195 0.862138720883195
Rsc1a1 ENSMUSG00000040715 0.244795877380543 0.367193816070815 0.974813114278522 0.974813114278522 0.157373898860655 0.367193816070815
Abca6 ENSMUSG00000044749 0.80942176660837 0.80942176660837 0.419612636269896 0.80942176660837 0.596196366886569 0.80942176660837
Slc25a26 ENSMUSG00000045100 0.0642116649698755 0.0963174974548132 0.0310160928827524 0.0930482786482571 0.874488989225705 0.874488989225705
Wnk1 ENSMUSG00000045962 0.0973373129804425 0.292011938941328 0.228990899792344 0.343486349688516 0.88077452822686 0.88077452822686
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Atp11c ENSMUSG00000062949 0.658309674246489 0.761082470309097 0.422464443492202 0.761082470309097 0.761082470309097 0.761082470309097
Ces3a ENSMUSG00000069922 0.350921972704152 0.790945866417902 0.607234665668771 0.790945866417902 0.790945866417902 0.790945866417902
Apoc4 ENSMUSG00000074336 0.987273119643355 0.987273119643355 0.94276155351988 0.987273119643355 0.201877311362099 0.605631934086298

Ethanol oxidation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acss1 ENSMUSG00000027452 0.852824011763922 0.852824011763922 0.334788274939822 0.852824011763922 0.687181916981449 0.852824011763922
Aldh1a1 ENSMUSG00000053279 0.930800389360814 0.930800389360814 0.764150293615528 0.930800389360814 0.610448736509107 0.930800389360814
Adh7 ENSMUSG00000055301 0.501175878511875 0.737788584995488 0.737788584995488 0.737788584995488 0.182850691866367 0.5485520755991

Peroxisomal protein import

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Paox ENSMUSG00000025464 0.655402386497108 0.983103579745663 0.397353958253998 0.983103579745663 0.996848608819353 0.996848608819353
Hao1 ENSMUSG00000027261 0.95416040513411 0.95416040513411 0.928131198252319 0.95416040513411 0.229373904811969 0.688121714435906
Pex10 ENSMUSG00000029047 0.66657116196345 0.66657116196345 0.169111255681988 0.253666883522982 0.103474927318682 0.253666883522982
Nudt7 ENSMUSG00000031767 0.591248622644815 0.773243898624926 0.431719694344876 0.773243898624926 0.773243898624926 0.773243898624926
Gnpat ENSMUSG00000031985 0.722355192412903 0.722355192412903 0.431674698818024 0.722355192412903 0.596747006562616 0.722355192412903
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Lonp2 ENSMUSG00000047866 0.183230890692813 0.307406718070393 0.204937812046928 0.307406718070393 0.449979624172674 0.449979624172674

Metabolism of lipids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pemt ENSMUSG00000000301 0.761183182115839 0.981108783328759 0.469693086782545 0.981108783328759 0.981108783328759 0.981108783328759
Pon1 ENSMUSG00000002588 0.786526928452999 0.786526928452999 0.436119577688839 0.658185292289621 0.438790194859748 0.658185292289621
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp17a1 ENSMUSG00000003555 0.389420562143718 0.406358017223015 0.181129646960049 0.406358017223015 0.406358017223015 0.406358017223015
Slc10a1 ENSMUSG00000021135 0.829311888914581 0.829311888914581 0.504738736186288 0.78283971681261 0.52189314454174 0.78283971681261
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Elovl2 ENSMUSG00000021364 0.911758016272639 0.911758016272639 0.778762754215036 0.911758016272639 0.710227553933736 0.911758016272639
Oxct1 ENSMUSG00000022186 0.0752796906043998 0.225839071813199 0.78833637711065 0.91511665827977 0.91511665827977 0.91511665827977
Acot9 ENSMUSG00000025287 0.974807686976734 0.974807686976734 0.740190266120286 0.974807686976734 0.501901325181496 0.974807686976734
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Hmgcs2 ENSMUSG00000027875 0.189976511224712 0.569929533674135 0.652576611045286 0.710570408299713 0.710570408299713 0.710570408299713
Gstm4 ENSMUSG00000027890 0.26298354884191 0.394475323262865 0.00463950970912761 0.0139185291273828 0.993700938975753 0.993700938975753
Alb ENSMUSG00000029368 0.0493120994724767 0.14793629841743 0.213089904884279 0.319634857326419 0.981075453371882 0.981075453371882
Slco1b2 ENSMUSG00000030236 0.470417262290596 0.477727064912666 0.477727064912666 0.477727064912666 0.182465458161341 0.477727064912666
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Cyp2r1 ENSMUSG00000030670 0.669775287648482 0.71055064465197 0.524859820953981 0.71055064465197 0.71055064465197 0.71055064465197
Gnpat ENSMUSG00000031985 0.722355192412903 0.722355192412903 0.431674698818024 0.722355192412903 0.596747006562616 0.722355192412903
Hsd17b13 ENSMUSG00000034528 0.600021392952413 0.600021392952413 0.17663573059565 0.4148740861618 0.276582724107866 0.4148740861618
Gc ENSMUSG00000035540 0.103801978664016 0.311405935992049 0.282024042280797 0.423036063421196 0.440485200286939 0.440485200286939
Thrsp ENSMUSG00000035686 0.908854129616767 0.946501420881211 0.354905116570767 0.946501420881211 0.946501420881211 0.946501420881211
Scd1 ENSMUSG00000037071 0.627130562693556 0.993701875928424 0.993701875928424 0.993701875928424 0.728267379696892 0.993701875928424
Elovl3 ENSMUSG00000038754 0.782935775862553 0.851777667560445 0.851777667560445 0.851777667560445 0.653560408657682 0.851777667560445
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Sgms1 ENSMUSG00000040451 0.452748404705691 0.679122607058537 0.933927805028281 0.933927805028281 0.334611881225443 0.679122607058537
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437
Fabp1 ENSMUSG00000054422 0.974698871826828 0.974698871826828 0.908822299680013 0.974698871826828 0.751021115781529 0.974698871826828
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663
Etnk2 ENSMUSG00000070644 0.846608146393741 0.846608146393741 0.245702708267281 0.737108124801842 0.590751046168787 0.846608146393741

Synthesis of bile acids and bile salts

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Abcb11 ENSMUSG00000027048 0.380641361847021 0.570962042770531 0.723470471720045 0.723470471720045 0.126886423080996 0.380659269242988
Slc27a5 ENSMUSG00000030382 0.180649041994843 0.541947125984528 0.797493578677298 0.797493578677298 0.522230435081058 0.783345652621587
Baat ENSMUSG00000039653 0.803633270160231 0.932933496669411 0.155731158774844 0.467193476324531 0.932933496669411 0.932933496669411
Hsd3b7 ENSMUSG00000042289 0.613243022726154 0.613243022726154 0.298288960940958 0.447433441411437 0.155045539435172 0.447433441411437

Platelet Aggregation (Plug Formation)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
F2 ENSMUSG00000027249 0.644141381078912 0.851327447765931 0.851327447765931 0.851327447765931 0.706326473711099 0.851327447765931
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168

Metabolism of fat-soluble vitamins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoa2 ENSMUSG00000005681 0.930693284401557 0.933937988165149 0.666546946107248 0.933937988165149 0.933937988165149 0.933937988165149
Akr1c6 ENSMUSG00000021210 0.603567570766535 0.864009362202797 0.864009362202797 0.864009362202797 0.660025726251689 0.864009362202797
Rbp4 ENSMUSG00000024990 0.303826275958889 0.472927186948364 0.710554937413083 0.710554937413083 0.315284791298909 0.472927186948364
Akr1b10 ENSMUSG00000061758 0.289253058757956 0.758164659508663 0.618862301685458 0.758164659508663 0.758164659508663 0.758164659508663
Ttr ENSMUSG00000061808 0.612871622305501 0.95268277235846 0.704327152799491 0.95268277235846 0.95268277235846 0.95268277235846
Ttpa ENSMUSG00000073988 0.821933800168012 0.949635284957978 0.767200051709053 0.949635284957978 0.949635284957978 0.949635284957978

Extracellular matrix organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mmp11 ENSMUSG00000000901 0.132103544071963 0.198155316107944 0.116453557257236 0.198155316107944 0.334770733603625 0.334770733603625
Tmprss6 ENSMUSG00000016942 0.52057168494727 0.780857527420905 0.514694675431701 0.780857527420905 0.840629655961761 0.840629655961761
Vtn ENSMUSG00000017344 0.716470231543603 0.96851995965851 0.457675129322445 0.96851995965851 0.96851995965851 0.96851995965851
Mmp19 ENSMUSG00000025355 0.56955851555123 0.854337773326846 0.408900041649255 0.854337773326846 0.955929507464818 0.955929507464818
Col5a2 ENSMUSG00000026042 0.880694707297781 0.880694707297781 0.452530478701461 0.678795718052192 0.361252130416552 0.678795718052192
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Ddr2 ENSMUSG00000026674 0.794379187946448 0.794379187946448 0.681329201816715 0.794379187946448 0.438569552058968 0.794379187946448
Itga6 ENSMUSG00000027111 0.85903634786436 0.896378668785114 0.896378668785114 0.896378668785114 0.713538815010198 0.896378668785114
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Ctsk ENSMUSG00000028111 0.952570277857798 0.952570277857798 0.463490510238419 0.774453940060263 0.516302626706842 0.774453940060263
Col4a1 ENSMUSG00000031502 0.827618285628854 0.827618285628854 0.0445234387141291 0.133570316142387 0.604046364232818 0.827618285628854
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Lamb2 ENSMUSG00000052911 0.410690749650905 0.616036124476358 0.0907310861443944 0.272193258433183 0.803448030246651 0.803448030246651
Plg ENSMUSG00000059481 0.626419323979619 0.755343462142364 0.755343462142364 0.755343462142364 0.723472355357624 0.755343462142364
Ttr ENSMUSG00000061808 0.612871622305501 0.95268277235846 0.704327152799491 0.95268277235846 0.95268277235846 0.95268277235846

CYP2E1 reactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2c29 ENSMUSG00000003053 0.171882595343206 0.515647786029618 0.35628846370655 0.534432695559825 0.668132359158564 0.668132359158564
Cyp2f2 ENSMUSG00000052974 0.49161741983438 0.955068462470323 0.636712308313548 0.955068462470323 0.990512657507331 0.990512657507331
Cyp2d22 ENSMUSG00000061740 0.779272555298107 0.779272555298107 0.707531907700734 0.779272555298107 0.243043530042471 0.729130590127412

MAP2K and MAPK activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fn1 ENSMUSG00000026193 0.512063565165981 0.512063565165981 0.324762265572079 0.512063565165981 0.496906799843989 0.512063565165981
Fga ENSMUSG00000028001 0.227514092399776 0.396541288401366 0.264360858934244 0.396541288401366 0.544075573855652 0.544075573855652
Fgb ENSMUSG00000033831 0.155172309292529 0.40281684050251 0.268544560335007 0.40281684050251 0.805886125804725 0.805886125804725
Fgg ENSMUSG00000033860 0.222536977914503 0.667610933743509 0.51345195275434 0.77017792913151 0.895949846531168 0.895949846531168
Lamtor3 ENSMUSG00000091512 0.233682521139504 0.350523781709255 0.556268070884538 0.556268070884538 0.087994017946473 0.263982053839419

royalblue

Oxidative phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Mpc1 ENSMUSG00000023861 0.831133881832284 0.977951790500772 0.977951790500772 0.977951790500772 0.537816434788182 0.977951790500772
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Thermogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Parkinson disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Prion disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Huntington disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Polr2i ENSMUSG00000019738 0.0214823034377907 0.0644469103133722 0.157345791658698 0.157345791658698 0.141566109148392 0.157345791658698
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Nrbf2 ENSMUSG00000075000 0.367487527174105 0.551231290761157 0.0924271338176613 0.277281401452984 0.949617856100883 0.949617856100883

Non-alcoholic fatty liver disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Nrbf2 ENSMUSG00000075000 0.367487527174105 0.551231290761157 0.0924271338176613 0.277281401452984 0.949617856100883 0.949617856100883

Amyotrophic lateral sclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Nrbf2 ENSMUSG00000075000 0.367487527174105 0.551231290761157 0.0924271338176613 0.277281401452984 0.949617856100883 0.949617856100883

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Nrbf2 ENSMUSG00000075000 0.367487527174105 0.551231290761157 0.0924271338176613 0.277281401452984 0.949617856100883 0.949617856100883

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
B4galnt1 ENSMUSG00000006731 0.887014798130651 0.890130254599512 0.719437660844724 0.890130254599512 0.890130254599512 0.890130254599512
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Acot2 ENSMUSG00000021226 0.261201603254677 0.274798520225642 0.0413024420721397 0.123907326216419 0.274798520225642 0.274798520225642
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ptges2 ENSMUSG00000026820 0.402184523217696 0.402184523217696 0.0902411217872005 0.259660493115475 0.173106995410317 0.259660493115475
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Coq3 ENSMUSG00000028247 0.678146678487688 0.710343841285398 0.710343841285398 0.710343841285398 0.681398582825287 0.710343841285398
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Coq7 ENSMUSG00000030652 0.710393503345441 0.880788454664201 0.324528907752397 0.880788454664201 0.880788454664201 0.880788454664201
Pde3b ENSMUSG00000030671 0.678494901923075 0.776086062939166 0.776086062939166 0.776086062939166 0.748982410511021 0.776086062939166
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Gpx4 ENSMUSG00000075706 0.254447540894318 0.381671311341477 0.0504607040866713 0.151382112260014 0.429379533844136 0.429379533844136

Retrograde endocannabinoid signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Ndufa11 ENSMUSG00000002379 0.362217313545741 0.672663268444684 0.483739489185686 0.672663268444684 0.672663268444684 0.672663268444684
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufs4 ENSMUSG00000021764 0.504344733321036 0.840475704490649 0.672691245461926 0.840475704490649 0.840475704490649 0.840475704490649
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Cardiac muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Cox6c ENSMUSG00000014313 0.550536342045853 0.82580451306878 0.524687688418697 0.82580451306878 0.959068023009298 0.959068023009298
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Uqcr11 ENSMUSG00000020163 0.242820363887145 0.538424406957408 0.358949604638272 0.538424406957408 0.764170924664981 0.764170924664981
Uqcrb ENSMUSG00000021520 0.764157145667162 0.927673862175575 0.927673862175575 0.927673862175575 0.91513195782338 0.927673862175575
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox7a2 ENSMUSG00000032330 0.165663917091977 0.248495875637965 0.12411642481938 0.248495875637965 0.397665126462714 0.397665126462714
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Cox5b ENSMUSG00000061518 0.610347483355891 0.915521225033836 0.245923218039678 0.737769654119033 0.933946356459194 0.933946356459194
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662

Citrate cycle (TCA cycle)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663

Carbon metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663

2-Oxocarboxylic acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078

Ubiquinone and other terpenoid-quinone biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coq3 ENSMUSG00000028247 0.678146678487688 0.710343841285398 0.710343841285398 0.710343841285398 0.681398582825287 0.710343841285398
Coq7 ENSMUSG00000030652 0.710393503345441 0.880788454664201 0.324528907752397 0.880788454664201 0.880788454664201 0.880788454664201

The citric acid (TCA) cycle and respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Timmdc1 ENSMUSG00000002846 0.550956392354937 0.826434588532405 0.224188089169467 0.672564267508401 0.918224636976456 0.918224636976456
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Bsg ENSMUSG00000023175 0.681269643417037 0.949627607245836 0.0933435617149505 0.280030685144852 0.949627607245836 0.949627607245836
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Timmdc1 ENSMUSG00000002846 0.550956392354937 0.826434588532405 0.224188089169467 0.672564267508401 0.918224636976456 0.918224636976456
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Timmdc1 ENSMUSG00000002846 0.550956392354937 0.826434588532405 0.224188089169467 0.672564267508401 0.918224636976456 0.918224636976456
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Complex I biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Timmdc1 ENSMUSG00000002846 0.550956392354937 0.826434588532405 0.224188089169467 0.672564267508401 0.918224636976456 0.918224636976456
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Ndufa9 ENSMUSG00000000399 0.663988050879386 0.719389477711837 0.716403931559469 0.719389477711837 0.719389477711837 0.719389477711837
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Ndufb2 ENSMUSG00000002416 0.358660127868607 0.537990191802911 0.21204389014589 0.537990191802911 0.865201979709424 0.865201979709424
Timmdc1 ENSMUSG00000002846 0.550956392354937 0.826434588532405 0.224188089169467 0.672564267508401 0.918224636976456 0.918224636976456
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Ndufs3 ENSMUSG00000005510 0.014782148633166 0.022173222949749 0.0033298280903148 0.0099894842709444 0.737139048113413 0.737139048113413
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Acot13 ENSMUSG00000006717 0.731208264966243 0.767107051476351 0.767107051476351 0.767107051476351 0.67262714958498 0.767107051476351
B4galnt1 ENSMUSG00000006731 0.887014798130651 0.890130254599512 0.719437660844724 0.890130254599512 0.890130254599512 0.890130254599512
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ndufs2 ENSMUSG00000013593 0.219696183620966 0.32954427543145 0.137347048732609 0.32954427543145 0.758083888426073 0.758083888426073
Ndufa2 ENSMUSG00000014294 0.0385491156897669 0.115647347069301 0.102184922315721 0.153277383473581 0.707429387573198 0.707429387573198
Ndufa1 ENSMUSG00000016427 0.0712773225386493 0.213831967615948 0.14817072519635 0.222256087794525 0.737066131474276 0.737066131474276
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufa12 ENSMUSG00000020022 0.257772081727269 0.773316245181807 0.858965147876681 0.868311902339741 0.868311902339741 0.868311902339741
Ndufs7 ENSMUSG00000020153 0.0109042424928692 0.0163563637393038 0.00261586019674696 0.00784758059024088 0.395083595442495 0.395083595442495
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Acot2 ENSMUSG00000021226 0.261201603254677 0.274798520225642 0.0413024420721397 0.123907326216419 0.274798520225642 0.274798520225642
Ndufs6 ENSMUSG00000021606 0.367352764727764 0.55753222219903 0.371688148132687 0.55753222219903 0.993700654712254 0.993700654712254
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Psmb5 ENSMUSG00000022193 0.0055800887995263 0.00837013319928945 1.54172596175964e-05 4.62517788527893e-05 0.0388883064706022 0.0388883064706022
Ndufb9 ENSMUSG00000022354 0.236688854130745 0.355033281196118 0.184519249238474 0.355033281196118 0.88701349485124 0.88701349485124
Ndufa6 ENSMUSG00000022450 0.501906060184581 0.859028559775678 0.859028559775678 0.859028559775678 0.704709610747547 0.859028559775678
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Cyc1 ENSMUSG00000022551 0.053793316502827 0.0806899747542405 0.00842650160276869 0.0252795048083061 0.818720000461422 0.818720000461422
Ndufb4 ENSMUSG00000022820 0.746064377688339 0.849714709540896 0.849714709540896 0.849714709540896 0.815831830613503 0.849714709540896
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Ndufa5 ENSMUSG00000023089 0.380126395250542 0.68273362988219 0.455155753254793 0.68273362988219 0.837395443413742 0.837395443413742
Bsg ENSMUSG00000023175 0.681269643417037 0.949627607245836 0.0933435617149505 0.280030685144852 0.949627607245836 0.949627607245836
Ndufv3 ENSMUSG00000024038 0.635395321961582 0.791349354284414 0.776241978260461 0.791349354284414 0.791349354284414 0.791349354284414
Ndufv2 ENSMUSG00000024099 0.761113846427559 0.996850732767574 0.638341981566734 0.996850732767574 0.996850732767574 0.996850732767574
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Uqcrc1 ENSMUSG00000025651 0.0306258931583227 0.0459388397374841 0.00251593927601331 0.00754781782803994 0.981043565871911 0.981043565871911
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Ndufs1 ENSMUSG00000025968 0.684277769415532 0.831208056800586 0.831208056800586 0.831208056800586 0.698839552765149 0.831208056800586
Ndufb3 ENSMUSG00000026032 0.785224417059526 0.859037905327215 0.491549056145472 0.859037905327215 0.859037905327215 0.859037905327215
Ndufa10 ENSMUSG00000026260 0.933925345054201 0.933925345054201 0.0683651284585865 0.205095385375759 0.550769966761601 0.826154950142401
Ptges2 ENSMUSG00000026820 0.402184523217696 0.402184523217696 0.0902411217872005 0.259660493115475 0.173106995410317 0.259660493115475
Ndufa8 ENSMUSG00000026895 0.054940320382814 0.082410480574221 0.00440822627076004 0.0132246788122801 0.285485322571609 0.285485322571609
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Ndufb5 ENSMUSG00000027673 0.542601018535149 0.93706232183395 0.710408195946325 0.93706232183395 0.93706232183395 0.93706232183395
Coq3 ENSMUSG00000028247 0.678146678487688 0.710343841285398 0.710343841285398 0.710343841285398 0.681398582825287 0.710343841285398
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Ndufc2 ENSMUSG00000030647 0.946500567745911 0.946500567745911 0.828105936879294 0.946500567745911 0.641254500878811 0.946500567745911
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Uqcrc2 ENSMUSG00000030884 0.457677695273194 0.822004801587159 0.713531474259168 0.822004801587159 0.822004801587159 0.822004801587159
Ndufb11 ENSMUSG00000031059 0.643819844920083 0.959037676938849 0.569433518801274 0.959037676938849 0.959037676938849 0.959037676938849
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Ndufb7 ENSMUSG00000033938 0.136210370052661 0.204315555078992 0.120091894118979 0.204315555078992 0.506949299875358 0.506949299875358
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Ndufa3 ENSMUSG00000035674 0.158748762063277 0.318254626236033 0.212169750824022 0.318254626236033 0.476804317253332 0.476804317253332
Ndufa13 ENSMUSG00000036199 0.225756862158295 0.677270586474885 0.664004305572126 0.965370791207707 0.965370791207707 0.965370791207707
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Ndufc1 ENSMUSG00000037152 0.239720726239936 0.359581089359904 0.0739703904668584 0.221911171400575 0.758063715763963 0.758063715763963
Ndufv1 ENSMUSG00000037916 0.205266752291946 0.307900128437919 0.126024092668626 0.307900128437919 0.474597104146309 0.474597104146309
Uqcrfs1 ENSMUSG00000038462 0.206626433882137 0.309939650823205 0.0401658670252885 0.120497601075865 0.943354453709665 0.943354453709665
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Ndufb10 ENSMUSG00000040048 0.886896064986535 0.987397871305688 0.481652154089404 0.987397871305688 0.987397871305688 0.987397871305688
Ndufa7 ENSMUSG00000041881 0.0580553566058098 0.174166069817429 0.322554903039412 0.483832354559117 0.553120613672422 0.553120613672422
Uqcrq ENSMUSG00000044894 0.352789711162579 0.529184566743868 0.221367527490264 0.529184566743868 0.800563273061031 0.800563273061031
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Uqcr10 ENSMUSG00000059534 0.288991619373207 0.433487429059811 0.28723257158507 0.433487429059811 0.6355318760917 0.6355318760917
Ndufs8 ENSMUSG00000059734 0.369328587569683 0.630024271620525 0.672629148841588 0.672629148841588 0.42001618108035 0.630024271620525
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
Uqcrh ENSMUSG00000063882 0.47671199679646 0.818845264963728 0.564192221538098 0.818845264963728 0.818845264963728 0.818845264963728
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662
Ndufb6 ENSMUSG00000071014 0.233602546726225 0.384277163980171 0.256184775986781 0.384277163980171 0.785354413455748 0.785354413455748
Gpx4 ENSMUSG00000075706 0.254447540894318 0.381671311341477 0.0504607040866713 0.151382112260014 0.429379533844136 0.429379533844136

Mitochondrial biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263

Formation of ATP by chemiosmotic coupling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165

Cristae formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165

TP53 Regulates Metabolic Genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662

Organelle biogenesis and maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp5f1 ENSMUSG00000000563 0.577664692701073 0.74914936996275 0.74914936996275 0.74914936996275 0.669796537587493 0.74914936996275
Atp5d ENSMUSG00000003072 0.022780737322554 0.0341711059838309 4.20444436813026e-05 0.000126133331043908 0.466302474669008 0.466302474669008
Atp5g1 ENSMUSG00000006057 0.365316925335409 0.547975388003114 0.191415642869413 0.547975388003114 0.678485203781178 0.678485203781178
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Atp5j ENSMUSG00000022890 0.346540940478249 0.519811410717373 0.21081674998044 0.519811410717373 0.877633744252329 0.877633744252329
Atp5o ENSMUSG00000022956 0.59926739642059 0.965359725914792 0.965359725914792 0.965359725914792 0.800533525522885 0.965359725914792
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182
Atp5a1 ENSMUSG00000025428 0.433581275167693 0.650371912751539 0.0496159942128684 0.148847982638605 0.779034481460854 0.779034481460854
Atp5c1 ENSMUSG00000025781 0.591149285151528 0.871440162125844 0.413211408566821 0.871440162125844 0.871440162125844 0.871440162125844
Mkks ENSMUSG00000027274 0.517151874033439 0.707564498080999 0.707564498080999 0.707564498080999 0.687172019350725 0.707564498080999
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Atp5h ENSMUSG00000034566 0.722282724805625 0.722282724805625 0.687094195924604 0.722282724805625 0.707546722859397 0.722282724805625
Atp5j2 ENSMUSG00000038690 0.28008235538548 0.472823715986908 0.315215810657938 0.472823715986908 0.734163762711249 0.734163762711249
Atp5l ENSMUSG00000038717 0.218121068397781 0.327181602596672 0.18080217687776 0.327181602596672 0.45717489013378 0.45717489013378
Atp5k ENSMUSG00000050856 0.0337569184401869 0.0822453825150199 0.0548302550100132 0.0822453825150199 0.779278246941165 0.779278246941165
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263

Citric acid cycle (TCA cycle)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078

Pyruvate metabolism and Citric Acid (TCA) cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhb ENSMUSG00000009863 0.464625159187269 0.785327235316028 0.583007647001797 0.785327235316028 0.785327235316028 0.785327235316028
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Sucla2 ENSMUSG00000022110 0.186095316461157 0.558285949383472 0.462426143280167 0.69363921492025 0.782289893440175 0.782289893440175
Aco2 ENSMUSG00000022477 0.626884879759948 0.626884879759948 0.209627266864673 0.486930893669771 0.324620595779848 0.486930893669771
Bsg ENSMUSG00000023175 0.681269643417037 0.949627607245836 0.0933435617149505 0.280030685144852 0.949627607245836 0.949627607245836
Idh3b ENSMUSG00000027406 0.890089099380495 0.996849600741056 0.996849600741056 0.996849600741056 0.556268291576509 0.996849600741056
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663

Transcriptional Regulation by TP53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.131924750923751 0.197887126385627 0.00168227632353347 0.00504682897060041 0.681283685908202 0.681283685908202
Cox7c ENSMUSG00000017778 0.563956343849529 1 0.82500332679072 1 1 1
Polr2i ENSMUSG00000019738 0.0214823034377907 0.0644469103133722 0.157345791658698 0.157345791658698 0.141566109148392 0.157345791658698
Ndufa4 ENSMUSG00000029632 0.390900687574123 0.715445943332399 0.476963962221599 0.715445943332399 0.79136630163275 0.79136630163275
Cox7b ENSMUSG00000031231 0.666806413067787 0.666891123207843 0.532539965873107 0.666891123207843 0.666891123207843 0.666891123207843
Cox4i1 ENSMUSG00000031818 0.0138301570599512 0.0207452355899268 0.00254703825648576 0.00764111476945728 0.346684901839869 0.346684901839869
Cox6b1 ENSMUSG00000036751 0.0677509074433006 0.203252722329902 0.139360700191254 0.209041050286881 0.604924967276546 0.604924967276546
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263
mt-Co1 ENSMUSG00000064351 0.212488394663997 0.318732591995995 0.0902596443938147 0.270778933181444 0.537735940898554 0.537735940898554
mt-Co2 ENSMUSG00000064354 0.800570402641693 0.800570402641693 0.298331536560705 0.800570402641693 0.569525754858337 0.800570402641693
mt-Co3 ENSMUSG00000064358 0.918274098490662 0.918274098490662 0.441078159178745 0.918274098490662 0.815865319917366 0.918274098490662

Mitochondrial protein import

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp5g3 ENSMUSG00000018770 0.0276912477892329 0.0415368716838493 0.00897311236529702 0.0269193370958911 0.558830046819036 0.558830046819036
Ndufb8 ENSMUSG00000025204 0.129827702001304 0.194741553001956 0.0322681783547679 0.0968045350643037 0.831078893628785 0.831078893628785
Atp5b ENSMUSG00000025393 0.837284245728182 0.837284245728182 0.0117815382269295 0.0353446146807885 0.752012049944642 0.837284245728182

Transcriptional activation of mitochondrial biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Idh2 ENSMUSG00000030541 0.294434798981551 0.587505865537078 0.587505865537078 0.587505865537078 0.521050471668744 0.587505865537078
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263

Glyoxylate metabolism and glycine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ogdh ENSMUSG00000020456 0.576246755962907 0.640111664740147 0.168125342301052 0.504376026903157 0.640111664740147 0.640111664740147
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Ndufab1 ENSMUSG00000030869 0.806373410825614 0.806373410825614 0.00282512838931753 0.00847538516795259 0.550629014272948 0.806373410825614
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663

Release of apoptotic factors from the mitochondria

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263

Activation of caspases through apoptosome-mediated cleavage

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gm10053 ENSMUSG00000058927 0.930786022703488 0.955935878957633 0.669771710867132 0.955935878957633 0.955935878957633 0.955935878957633
Cycs ENSMUSG00000063694 0.514626393981064 0.887011991011263 0.887011991011263 0.887011991011263 0.821979742760419 0.887011991011263

Pyruvate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dld ENSMUSG00000020664 0.224384297046034 0.541866581457761 0.361244387638507 0.541866581457761 0.740203133844569 0.740203133844569
Bsg ENSMUSG00000023175 0.681269643417037 0.949627607245836 0.0933435617149505 0.280030685144852 0.949627607245836 0.949627607245836
Pdha1 ENSMUSG00000031299 0.311451102326282 0.526240328151284 0.350826885434189 0.526240328151284 0.887015136474663 0.887015136474663

skyblue

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt3 ENSMUSG00000001665 0.142652165305696 0.2223169339696 0.238281192862323 0.238281192862323 0.148211289313066 0.2223169339696
Prodh ENSMUSG00000003526 0.202510508628617 0.607531525885852 0.828130885548806 0.902623894024535 0.902623894024535 0.902623894024535
Shpk ENSMUSG00000005951 0.283809631126558 0.716490897208455 0.716490897208455 0.716490897208455 0.693020163416945 0.716490897208455
Acyp1 ENSMUSG00000008822 0.330790688803197 0.689993671423548 0.459995780949032 0.689993671423548 0.722329406868325 0.722329406868325
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Hyal2 ENSMUSG00000010047 0.48942744786296 0.734141171794439 0.229052503562392 0.687157510687176 0.758176670079121 0.758176670079121
Acsf3 ENSMUSG00000015016 0.00553114097232579 0.0123128247998871 0.0082085498665914 0.0123128247998871 0.984232074463724 0.984232074463724
Mocs2 ENSMUSG00000015536 0.806680656903379 0.905744744980815 0.499388168742212 0.905744744980815 0.905744744980815 0.905744744980815
Chdh ENSMUSG00000015970 0.949595160247374 0.949595160247374 0.946459933959203 0.949595160247374 0.868195875331811 0.949595160247374
Echdc1 ENSMUSG00000019883 0.201098716309136 0.603296148927409 0.666960068823507 0.927673789696071 0.927673789696071 0.927673789696071
P4ha1 ENSMUSG00000019916 0.0491662193484616 0.0737493290226924 0.0025456415538655 0.00763692466159649 0.431292769128722 0.431292769128722
Enpp3 ENSMUSG00000019989 0.642655512232708 0.772223905437412 0.772223905437412 0.772223905437412 0.580113536083206 0.772223905437412
Pcbd1 ENSMUSG00000020098 0.429376538640888 0.686461294346774 0.457640862897849 0.686461294346774 0.69590355919032 0.69590355919032
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Entpd5 ENSMUSG00000021236 0.918274589470418 0.918274589470418 0.791439919981153 0.918274589470418 0.912012397227267 0.918274589470418
Oxsm ENSMUSG00000021786 0.758180359241639 0.758180359241639 0.180826631263764 0.542479893791292 0.635663709117706 0.758180359241639
Btd ENSMUSG00000021900 0.865240311694153 0.865240311694153 0.246422399932225 0.493263561460635 0.32884237430709 0.493263561460635
Esd ENSMUSG00000021996 0.41774364529658 0.548262366920895 0.548262366920895 0.548262366920895 0.356986281248433 0.548262366920895
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Naprt1 ENSMUSG00000022574 0.332755638894034 0.499133458341051 0.148198924264533 0.444596772793599 0.695924734455875 0.695924734455875
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Rpp14 ENSMUSG00000023156 0.949647631626684 0.949647631626684 0.93708255905099 0.949647631626684 0.556223661000286 0.949647631626684
Acy1 ENSMUSG00000023262 0.139471125162618 0.367206679450222 0.244804452966815 0.367206679450222 0.672705437958384 0.672705437958384
Enpp4 ENSMUSG00000023961 0.391126421391088 0.586689632086632 0.361189104947337 0.586689632086632 0.968517535572989 0.968517535572989
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Aldh1a7 ENSMUSG00000024747 0.862062112493193 0.862062112493193 0.566815752275522 0.862062112493193 0.638380166686897 0.862062112493193
Papss2 ENSMUSG00000024899 0.98425487182645 0.98425487182645 0.621598489016556 0.98425487182645 0.725302103729692 0.98425487182645
Gyk ENSMUSG00000025059 0.99685090403113 0.99685090403113 0.896329983018513 0.99685090403113 0.566728186207889 0.99685090403113
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Hsd17b7 ENSMUSG00000026675 0.211045912909335 0.633137738728006 0.675492049788387 0.675492049788387 0.661090689138681 0.675492049788387
Aldh9a1 ENSMUSG00000026687 0.276556549149272 0.414834823723908 0.259474936083486 0.414834823723908 0.716411876669043 0.716411876669043
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Aldob ENSMUSG00000028307 0.572304878861035 0.981106543463403 0.749154569387916 0.981106543463403 0.981106543463403 0.981106543463403
Aco1 ENSMUSG00000028405 0.356996139602815 0.467209049606395 0.2579490573244 0.467209049606395 0.467209049606395 0.467209049606395
Gpx7 ENSMUSG00000028597 0.561585583760286 0.761186026694438 0.761186026694438 0.761186026694438 0.452885255848918 0.761186026694438
Scp2 ENSMUSG00000028603 0.448159568784257 0.883905411206189 0.883905411206189 0.883905411206189 0.859040615189533 0.883905411206189
Cda ENSMUSG00000028755 0.681014940808857 0.681014940808857 0.288997842058505 0.681014940808857 0.51883585145554 0.681014940808857
Khk ENSMUSG00000029162 0.254534375733653 0.580353216556064 0.452891575062509 0.580353216556064 0.580353216556064 0.580353216556064
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Sdsl ENSMUSG00000029596 0.17553471365084 0.26330207047626 0.00865897532533421 0.0259769259760026 0.896331054405964 0.896331054405964
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Nat8 ENSMUSG00000030004 0.63553637360915 0.905693515298326 0.831132914980051 0.905693515298326 0.905693515298326 0.905693515298326
Oat ENSMUSG00000030934 0.719345686105045 0.834222388526471 0.788250737488418 0.834222388526471 0.834222388526471 0.834222388526471
Acsm3 ENSMUSG00000030935 0.621013438992086 0.949199693136249 0.946059606411416 0.949199693136249 0.949199693136249 0.949199693136249
Ebp ENSMUSG00000031168 0.937061311215017 0.937061311215017 0.849714410957955 0.937061311215017 0.599387025174043 0.937061311215017
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Hsd17b2 ENSMUSG00000031844 0.555556494635131 0.833334741952697 0.915039174258537 0.915039174258537 0.368803311338788 0.833334741952697
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Sc5d ENSMUSG00000032018 0.30191068460125 0.905732053803751 0.687186120707919 0.905736195032437 0.905736195032437 0.905736195032437
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Dpyd ENSMUSG00000033308 0.572189937160166 0.843566726988339 0.459973133587052 0.843566726988339 0.843566726988339 0.843566726988339
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Spr ENSMUSG00000033735 0.143660801289439 0.215491201934159 0.00540633218151561 0.0162189965445468 0.519696982832618 0.519696982832618
Dak ENSMUSG00000034371 0.188710542864303 0.283065814296454 0.12510660922972 0.283065814296454 0.749086572223298 0.749086572223298
Galm ENSMUSG00000035473 0.968508593234154 0.968508593234154 0.940228207460616 0.968508593234154 0.886969256871643 0.968508593234154
Entpd8 ENSMUSG00000036813 0.697886732327941 0.704829623547044 0.580733385230905 0.704829623547044 0.704829623547044 0.704829623547044
Pafah2 ENSMUSG00000037366 0.222863331350515 0.334294997025772 0.135195406774909 0.334294997025772 0.746163712266164 0.746163712266164
Gnpnat1 ENSMUSG00000037722 0.474594978878368 0.840469641273019 0.713533645956745 0.840469641273019 0.840469641273019 0.840469641273019
Inpp4b ENSMUSG00000037940 0.448123106249843 0.672184659374764 0.965369817330894 0.965369817330894 0.305818204710046 0.672184659374764
Dcxr ENSMUSG00000039450 0.0246345216953567 0.07390356508607 0.516931591091901 0.516931591091901 0.384474977311131 0.516931591091901
Lap3 ENSMUSG00000039682 0.959080176349547 0.959080176349547 0.361141178540386 0.959080176349547 0.865189941103166 0.959080176349547
Alg14 ENSMUSG00000039887 0.761131263640342 0.761131263640342 0.666931460357437 0.761131263640342 0.344656500252511 0.761131263640342
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327
Pklr ENSMUSG00000041237 0.993580828519077 0.993580828519077 0.617856171232851 0.993580828519077 0.81569719646782 0.993580828519077
Car8 ENSMUSG00000041261 0.95279358576612 0.95279358576612 0.743193292950088 0.95279358576612 0.716484716163237 0.95279358576612
Csgalnact2 ENSMUSG00000042042 0.233565700839995 0.700697102519986 0.797486341970503 0.837382767107545 0.837382767107545 0.837382767107545
Bdh1 ENSMUSG00000046598 0.55195692926026 0.55195692926026 0.370928296223045 0.55195692926026 0.0520806765559679 0.156242029667904
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332
Sephs2 ENSMUSG00000049091 0.629894085323374 0.94484112798506 0.236747218795673 0.71024165638702 0.987400303068685 0.987400303068685
Suox ENSMUSG00000049858 0.908838036234562 0.908838036234562 0.241594122577139 0.724782367731417 0.704608580986811 0.908838036234562
Sgms2 ENSMUSG00000050931 0.834217238489034 0.834217238489034 0.621629622116372 0.834217238489034 0.770089591493942 0.834217238489034
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Lipg ENSMUSG00000053846 0.791101575304333 0.958989163598133 0.7099296795158 0.958989163598133 0.958989163598133 0.958989163598133
Fdps ENSMUSG00000059743 0.494374285256623 0.494374285256623 0.115529537777789 0.346588613333368 0.365425775620161 0.494374285256623
Hsd3b3 ENSMUSG00000062410 0.893694107365368 0.938456833350176 0.938456833350176 0.938456833350176 0.677605682671855 0.938456833350176
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159
Mgam ENSMUSG00000068587 0.828128976981326 0.828128976981326 0.762562483818714 0.828128976981326 0.796014604574252 0.828128976981326
Rdh16 ENSMUSG00000069456 0.772420868098837 0.772420868098837 0.730787582472195 0.772420868098837 0.707033465455021 0.772420868098837
Acnat1 ENSMUSG00000070985 0.627017017264942 0.911021490681825 0.486304008874767 0.911021490681825 0.911021490681825 0.911021490681825
Gsta1 ENSMUSG00000074183 0.383003371989907 0.737819879667914 0.737819879667914 0.737819879667914 0.566091772673614 0.737819879667914
Cml5 ENSMUSG00000079494 0.809674014037058 0.809699959441315 0.809699959441315 0.809699959441315 0.731187153431239 0.809699959441315
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Biosynthesis of amino acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Acy1 ENSMUSG00000023262 0.139471125162618 0.367206679450222 0.244804452966815 0.367206679450222 0.672705437958384 0.672705437958384
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Aldob ENSMUSG00000028307 0.572304878861035 0.981106543463403 0.749154569387916 0.981106543463403 0.981106543463403 0.981106543463403
Aco1 ENSMUSG00000028405 0.356996139602815 0.467209049606395 0.2579490573244 0.467209049606395 0.467209049606395 0.467209049606395
Sdsl ENSMUSG00000029596 0.17553471365084 0.26330207047626 0.00865897532533421 0.0259769259760026 0.896331054405964 0.896331054405964
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Pklr ENSMUSG00000041237 0.993580828519077 0.993580828519077 0.617856171232851 0.993580828519077 0.81569719646782 0.993580828519077
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332

Peroxisome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Pex16 ENSMUSG00000027222 0.038223126595876 0.114669379787628 0.264563891892219 0.396845837838329 0.596705985390053 0.596705985390053
Abcd3 ENSMUSG00000028127 0.5352345679375 0.616025305519346 0.109214676435002 0.327644029305005 0.616025305519346 0.616025305519346
Scp2 ENSMUSG00000028603 0.448159568784257 0.883905411206189 0.883905411206189 0.883905411206189 0.859040615189533 0.883905411206189
Prdx1 ENSMUSG00000028691 0.785361709099146 0.874553570974607 0.752163194634971 0.874553570974607 0.874553570974607 0.874553570974607
Pex11a ENSMUSG00000030545 0.136247989422121 0.213981146917408 0.142654097944938 0.213981146917408 0.474608422005179 0.474608422005179
Pex11g ENSMUSG00000069633 0.806680127879328 0.806680127879328 0.429423733542585 0.806680127879328 0.72239743901413 0.806680127879328
Acnat1 ENSMUSG00000070985 0.627017017264942 0.911021490681825 0.486304008874767 0.911021490681825 0.911021490681825 0.911021490681825

Cholesterol metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Soat2 ENSMUSG00000023045 0.0288517213191708 0.0865551639575124 0.993642942871853 0.993642942871853 0.622111525047928 0.933167287571893
Abcg8 ENSMUSG00000024254 0.911935191938652 0.914719077172943 0.756659424748474 0.914719077172943 0.914719077172943 0.914719077172943
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Abcg5 ENSMUSG00000040505 0.599474040803033 0.821583333391364 0.821583333391364 0.821583333391364 0.576873686324377 0.821583333391364
Pcsk9 ENSMUSG00000044254 0.717660369466232 0.904695357599178 0.904695357599178 0.904695357599178 0.807569359073865 0.904695357599178
Lipg ENSMUSG00000053846 0.791101575304333 0.958989163598133 0.7099296795158 0.958989163598133 0.958989163598133 0.958989163598133

Glutathione metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt3 ENSMUSG00000001665 0.142652165305696 0.2223169339696 0.238281192862323 0.238281192862323 0.148211289313066 0.2223169339696
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Gpx7 ENSMUSG00000028597 0.561585583760286 0.761186026694438 0.761186026694438 0.761186026694438 0.452885255848918 0.761186026694438
Nat8 ENSMUSG00000030004 0.63553637360915 0.905693515298326 0.831132914980051 0.905693515298326 0.905693515298326 0.905693515298326
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Lap3 ENSMUSG00000039682 0.959080176349547 0.959080176349547 0.361141178540386 0.959080176349547 0.865189941103166 0.959080176349547
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327
Gsta1 ENSMUSG00000074183 0.383003371989907 0.737819879667914 0.737819879667914 0.737819879667914 0.566091772673614 0.737819879667914
Cml5 ENSMUSG00000079494 0.809674014037058 0.809699959441315 0.809699959441315 0.809699959441315 0.731187153431239 0.809699959441315

Drug metabolism - other enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt3 ENSMUSG00000001665 0.142652165305696 0.2223169339696 0.238281192862323 0.238281192862323 0.148211289313066 0.2223169339696
Cda ENSMUSG00000028755 0.681014940808857 0.681014940808857 0.288997842058505 0.681014940808857 0.51883585145554 0.681014940808857
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Ces1f ENSMUSG00000031725 0.933349908444126 0.933349908444126 0.87747331885062 0.933349908444126 0.898491204152304 0.933349908444126
Ces2e ENSMUSG00000031886 0.849115473492365 0.981030263073095 0.840103835030062 0.981030263073095 0.981030263073095 0.981030263073095
Dpyd ENSMUSG00000033308 0.572189937160166 0.843566726988339 0.459973133587052 0.843566726988339 0.843566726988339 0.843566726988339
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Ces2a ENSMUSG00000055730 0.434017394386344 0.614614681425229 0.614614681425229 0.614614681425229 0.172509942632925 0.517529827898775
Ces2c ENSMUSG00000061825 0.729785579790022 0.987333299000336 0.883525454824552 0.987333299000336 0.987333299000336 0.987333299000336
Gsta1 ENSMUSG00000074183 0.383003371989907 0.737819879667914 0.737819879667914 0.737819879667914 0.566091772673614 0.737819879667914
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Biosynthesis of cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Mocs2 ENSMUSG00000015536 0.806680656903379 0.905744744980815 0.499388168742212 0.905744744980815 0.905744744980815 0.905744744980815
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Oxsm ENSMUSG00000021786 0.758180359241639 0.758180359241639 0.180826631263764 0.542479893791292 0.635663709117706 0.758180359241639
Naprt1 ENSMUSG00000022574 0.332755638894034 0.499133458341051 0.148198924264533 0.444596772793599 0.695924734455875 0.695924734455875
Ak3 ENSMUSG00000024782 0.752166380705741 0.752166380705741 0.214014685277646 0.642044055832938 0.672718526490904 0.752166380705741
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Spr ENSMUSG00000033735 0.143660801289439 0.215491201934159 0.00540633218151561 0.0162189965445468 0.519696982832618 0.519696982832618
Pklr ENSMUSG00000041237 0.993580828519077 0.993580828519077 0.617856171232851 0.993580828519077 0.81569719646782 0.993580828519077
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Carbon metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Esd ENSMUSG00000021996 0.41774364529658 0.548262366920895 0.548262366920895 0.548262366920895 0.356986281248433 0.548262366920895
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Aldob ENSMUSG00000028307 0.572304878861035 0.981106543463403 0.749154569387916 0.981106543463403 0.981106543463403 0.981106543463403
Aco1 ENSMUSG00000028405 0.356996139602815 0.467209049606395 0.2579490573244 0.467209049606395 0.467209049606395 0.467209049606395
Sdsl ENSMUSG00000029596 0.17553471365084 0.26330207047626 0.00865897532533421 0.0259769259760026 0.896331054405964 0.896331054405964
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Dak ENSMUSG00000034371 0.188710542864303 0.283065814296454 0.12510660922972 0.283065814296454 0.749086572223298 0.749086572223298
Pklr ENSMUSG00000041237 0.993580828519077 0.993580828519077 0.617856171232851 0.993580828519077 0.81569719646782 0.993580828519077

Arginine biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Acy1 ENSMUSG00000023262 0.139471125162618 0.367206679450222 0.244804452966815 0.367206679450222 0.672705437958384 0.672705437958384
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332

2-Oxocarboxylic acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Acy1 ENSMUSG00000023262 0.139471125162618 0.367206679450222 0.244804452966815 0.367206679450222 0.672705437958384 0.672705437958384
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Aco1 ENSMUSG00000028405 0.356996139602815 0.467209049606395 0.2579490573244 0.467209049606395 0.467209049606395 0.467209049606395
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332

ABC transporters

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Abcg8 ENSMUSG00000024254 0.911935191938652 0.914719077172943 0.756659424748474 0.914719077172943 0.914719077172943 0.914719077172943
Abcc2 ENSMUSG00000025194 0.376973120889704 0.636196787513894 0.949050671545576 0.949050671545576 0.424131191675929 0.636196787513894
Abcb6 ENSMUSG00000026198 0.247596349554012 0.371394524331018 0.000271559937532504 0.000814679812597511 0.478958347449782 0.478958347449782
Abcd3 ENSMUSG00000028127 0.5352345679375 0.616025305519346 0.109214676435002 0.327644029305005 0.616025305519346 0.616025305519346
Abcg2 ENSMUSG00000029802 0.927673821909211 0.927673821909211 0.618626516495293 0.927673821909211 0.638131013910296 0.927673821909211
Abcg5 ENSMUSG00000040505 0.599474040803033 0.821583333391364 0.821583333391364 0.821583333391364 0.576873686324377 0.821583333391364
Abca9 ENSMUSG00000041797 0.303846769149494 0.371742134298637 0.371742134298637 0.371742134298637 0.098901026209402 0.296703078628206

Folate biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mocs2 ENSMUSG00000015536 0.806680656903379 0.905744744980815 0.499388168742212 0.905744744980815 0.905744744980815 0.905744744980815
Pcbd1 ENSMUSG00000020098 0.429376538640888 0.686461294346774 0.457640862897849 0.686461294346774 0.69590355919032 0.69590355919032
Spr ENSMUSG00000033735 0.143660801289439 0.215491201934159 0.00540633218151561 0.0162189965445468 0.519696982832618 0.519696982832618
Mocos ENSMUSG00000039616 0.669692540537422 0.837295546148563 0.837295546148563 0.837295546148563 0.701510555554259 0.837295546148563
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159

Fat digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Abcg8 ENSMUSG00000024254 0.911935191938652 0.914719077172943 0.756659424748474 0.914719077172943 0.914719077172943 0.914719077172943
Mttp ENSMUSG00000028158 0.580388257487043 0.870582386230564 0.517174551179467 0.870582386230564 0.883898409450144 0.883898409450144
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Abcg5 ENSMUSG00000040505 0.599474040803033 0.821583333391364 0.821583333391364 0.821583333391364 0.576873686324377 0.821583333391364

Fatty acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acsf3 ENSMUSG00000015016 0.00553114097232579 0.0123128247998871 0.0082085498665914 0.0123128247998871 0.984232074463724 0.984232074463724
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Oxsm ENSMUSG00000021786 0.758180359241639 0.758180359241639 0.180826631263764 0.542479893791292 0.635663709117706 0.758180359241639
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Rpp14 ENSMUSG00000023156 0.949647631626684 0.949647631626684 0.93708255905099 0.949647631626684 0.556223661000286 0.949647631626684
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Scp2 ENSMUSG00000028603 0.448159568784257 0.883905411206189 0.883905411206189 0.883905411206189 0.859040615189533 0.883905411206189

Bile secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc22a1 ENSMUSG00000023829 0.748466660946456 0.88480430167401 0.509946124581043 0.88480430167401 0.88480430167401 0.88480430167401
Abcg8 ENSMUSG00000024254 0.911935191938652 0.914719077172943 0.756659424748474 0.914719077172943 0.914719077172943 0.914719077172943
Abcc2 ENSMUSG00000025194 0.376973120889704 0.636196787513894 0.949050671545576 0.949050671545576 0.424131191675929 0.636196787513894
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Abcg2 ENSMUSG00000029802 0.927673821909211 0.927673821909211 0.618626516495293 0.927673821909211 0.638131013910296 0.927673821909211
Abcg5 ENSMUSG00000040505 0.599474040803033 0.821583333391364 0.821583333391364 0.821583333391364 0.576873686324377 0.821583333391364
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Acnat1 ENSMUSG00000070985 0.627017017264942 0.911021490681825 0.486304008874767 0.911021490681825 0.911021490681825 0.911021490681825
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Selenocompound metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Papss2 ENSMUSG00000024899 0.98425487182645 0.98425487182645 0.621598489016556 0.98425487182645 0.725302103729692 0.98425487182645
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Sephs2 ENSMUSG00000049091 0.629894085323374 0.94484112798506 0.236747218795673 0.71024165638702 0.987400303068685 0.987400303068685
Pstk ENSMUSG00000063179 0.896343724211224 0.896343724211224 0.175651975956289 0.526955927868866 0.737158229605804 0.896343724211224

Ascorbate and aldarate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Aldh9a1 ENSMUSG00000026687 0.276556549149272 0.414834823723908 0.259474936083486 0.414834823723908 0.716411876669043 0.716411876669043
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

beta-Alanine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Aldh9a1 ENSMUSG00000026687 0.276556549149272 0.414834823723908 0.259474936083486 0.414834823723908 0.716411876669043 0.716411876669043
Dpyd ENSMUSG00000033308 0.572189937160166 0.843566726988339 0.459973133587052 0.843566726988339 0.843566726988339 0.843566726988339

Biosynthesis of unsaturated fatty acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Scp2 ENSMUSG00000028603 0.448159568784257 0.883905411206189 0.883905411206189 0.883905411206189 0.859040615189533 0.883905411206189
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159
Acnat1 ENSMUSG00000070985 0.627017017264942 0.911021490681825 0.486304008874767 0.911021490681825 0.911021490681825 0.911021490681825

Steroid biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Soat2 ENSMUSG00000023045 0.0288517213191708 0.0865551639575124 0.993642942871853 0.993642942871853 0.622111525047928 0.933167287571893
Hsd17b7 ENSMUSG00000026675 0.211045912909335 0.633137738728006 0.675492049788387 0.675492049788387 0.661090689138681 0.675492049788387
Ebp ENSMUSG00000031168 0.937061311215017 0.937061311215017 0.849714410957955 0.937061311215017 0.599387025174043 0.937061311215017
Sc5d ENSMUSG00000032018 0.30191068460125 0.905732053803751 0.687186120707919 0.905736195032437 0.905736195032437 0.905736195032437

Pantothenate and CoA biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Enpp3 ENSMUSG00000019989 0.642655512232708 0.772223905437412 0.772223905437412 0.772223905437412 0.580113536083206 0.772223905437412
Dpyd ENSMUSG00000033308 0.572189937160166 0.843566726988339 0.459973133587052 0.843566726988339 0.843566726988339 0.843566726988339
Vnn1 ENSMUSG00000037440 0.533779748328309 0.867483931239956 0.702651461268161 0.867483931239956 0.867483931239956 0.867483931239956

Steroid hormone biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2d26 ENSMUSG00000022445 0.945120847598291 0.945120847598291 0.390323041048996 0.945120847598291 0.737169364045036 0.945120847598291
Hsd17b7 ENSMUSG00000026675 0.211045912909335 0.633137738728006 0.675492049788387 0.675492049788387 0.661090689138681 0.675492049788387
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Hsd17b2 ENSMUSG00000031844 0.555556494635131 0.833334741952697 0.915039174258537 0.915039174258537 0.368803311338788 0.833334741952697
Hsd3b3 ENSMUSG00000062410 0.893694107365368 0.938456833350176 0.938456833350176 0.938456833350176 0.677605682671855 0.938456833350176
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Drug metabolism - cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gstt3 ENSMUSG00000001665 0.142652165305696 0.2223169339696 0.238281192862323 0.238281192862323 0.148211289313066 0.2223169339696
Fmo4 ENSMUSG00000026692 0.544891930445826 0.81733789566874 0.889974147169012 0.889974147169012 0.417406196614923 0.81733789566874
Fmo5 ENSMUSG00000028088 0.607621169374195 0.624387323937707 0.450429600197727 0.624387323937707 0.624387323937707 0.624387323937707
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Gsta1 ENSMUSG00000074183 0.383003371989907 0.737819879667914 0.737819879667914 0.737819879667914 0.566091772673614 0.737819879667914
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Biotin metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Oxsm ENSMUSG00000021786 0.758180359241639 0.758180359241639 0.180826631263764 0.542479893791292 0.635663709117706 0.758180359241639
Btd ENSMUSG00000021900 0.865240311694153 0.865240311694153 0.246422399932225 0.493263561460635 0.32884237430709 0.493263561460635

Arginine and proline metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prodh ENSMUSG00000003526 0.202510508628617 0.607531525885852 0.828130885548806 0.902623894024535 0.902623894024535 0.902623894024535
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
P4ha1 ENSMUSG00000019916 0.0491662193484616 0.0737493290226924 0.0025456415538655 0.00763692466159649 0.431292769128722 0.431292769128722
Aldh9a1 ENSMUSG00000026687 0.276556549149272 0.414834823723908 0.259474936083486 0.414834823723908 0.716411876669043 0.716411876669043
Oat ENSMUSG00000030934 0.719345686105045 0.834222388526471 0.788250737488418 0.834222388526471 0.834222388526471 0.834222388526471
Lap3 ENSMUSG00000039682 0.959080176349547 0.959080176349547 0.361141178540386 0.959080176349547 0.865189941103166 0.959080176349547

Vitamin digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Btd ENSMUSG00000021900 0.865240311694153 0.865240311694153 0.246422399932225 0.493263561460635 0.32884237430709 0.493263561460635
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Maturity onset diabetes of the young

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnf4a ENSMUSG00000017950 0.783573814525451 0.977701622492717 0.977701622492717 0.977701622492717 0.407932088928937 0.977701622492717
Hnf1b ENSMUSG00000020679 0.858626725387928 0.858626725387928 0.742180604525095 0.858626725387928 0.714972856685596 0.858626725387928
Nr5a2 ENSMUSG00000026398 0.852293338097077 0.852293338097077 0.578852899524347 0.852293338097077 0.727389060769423 0.852293338097077
Pklr ENSMUSG00000041237 0.993580828519077 0.993580828519077 0.617856171232851 0.993580828519077 0.81569719646782 0.993580828519077

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Prodh ENSMUSG00000003526 0.202510508628617 0.607531525885852 0.828130885548806 0.902623894024535 0.902623894024535 0.902623894024535
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Shpk ENSMUSG00000005951 0.283809631126558 0.716490897208455 0.716490897208455 0.716490897208455 0.693020163416945 0.716490897208455
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Hyal2 ENSMUSG00000010047 0.48942744786296 0.734141171794439 0.229052503562392 0.687157510687176 0.758176670079121 0.758176670079121
Chp1 ENSMUSG00000014077 0.902623764200359 0.902623764200359 0.196925710211753 0.59077713063526 0.825073417142427 0.902623764200359
Acsf3 ENSMUSG00000015016 0.00553114097232579 0.0123128247998871 0.0082085498665914 0.0123128247998871 0.984232074463724 0.984232074463724
Chdh ENSMUSG00000015970 0.949595160247374 0.949595160247374 0.946459933959203 0.949595160247374 0.868195875331811 0.949595160247374
Cyb5r3 ENSMUSG00000018042 0.365165078617838 0.547747617926757 0.0482094193218234 0.14462825796547 0.601957826226395 0.601957826226395
Iyd ENSMUSG00000019762 0.904992273441103 0.904992273441103 0.848170897654359 0.904992273441103 0.43603284409895 0.904992273441103
Ppa1 ENSMUSG00000020089 0.83431095975837 0.83431095975837 0.186075536401502 0.558226609204507 0.734266365885317 0.83431095975837
Pcbd1 ENSMUSG00000020098 0.429376538640888 0.686461294346774 0.457640862897849 0.686461294346774 0.69590355919032 0.69590355919032
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Sdc1 ENSMUSG00000020592 0.494320726670871 0.85581086889017 0.85581086889017 0.85581086889017 0.574704078670699 0.85581086889017
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Entpd5 ENSMUSG00000021236 0.918274589470418 0.918274589470418 0.791439919981153 0.918274589470418 0.912012397227267 0.918274589470418
Esd ENSMUSG00000021996 0.41774364529658 0.548262366920895 0.548262366920895 0.548262366920895 0.356986281248433 0.548262366920895
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Naprt1 ENSMUSG00000022574 0.332755638894034 0.499133458341051 0.148198924264533 0.444596772793599 0.695924734455875 0.695924734455875
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Slc22a1 ENSMUSG00000023829 0.748466660946456 0.88480430167401 0.509946124581043 0.88480430167401 0.88480430167401 0.88480430167401
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Cyb5 ENSMUSG00000024646 0.728310614186649 0.812784901466279 0.342755071240364 0.812784901466279 0.812784901466279 0.812784901466279
Papss2 ENSMUSG00000024899 0.98425487182645 0.98425487182645 0.621598489016556 0.98425487182645 0.725302103729692 0.98425487182645
Gyk ENSMUSG00000025059 0.99685090403113 0.99685090403113 0.896329983018513 0.99685090403113 0.566728186207889 0.99685090403113
Abcc2 ENSMUSG00000025194 0.376973120889704 0.636196787513894 0.949050671545576 0.949050671545576 0.424131191675929 0.636196787513894
Slc25a10 ENSMUSG00000025792 0.283440017805979 0.715358573142372 0.476905715428248 0.715358573142372 0.97480422348121 0.97480422348121
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Dbi ENSMUSG00000026385 0.537837801858057 0.94650693842806 0.94650693842806 0.94650693842806 0.63283743275398 0.94650693842806
Hsd17b7 ENSMUSG00000026675 0.211045912909335 0.633137738728006 0.675492049788387 0.675492049788387 0.661090689138681 0.675492049788387
Slc25a12 ENSMUSG00000027010 0.569560069233245 0.704718632962594 0.672675741842173 0.704718632962594 0.704718632962594 0.704718632962594
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Aadac ENSMUSG00000027761 0.545590012832295 0.573606596756578 0.329528496835431 0.573606596756578 0.573606596756578 0.573606596756578
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Aldob ENSMUSG00000028307 0.572304878861035 0.981106543463403 0.749154569387916 0.981106543463403 0.981106543463403 0.981106543463403
Slc35d1 ENSMUSG00000028521 0.62722561410699 0.984256909059021 0.984256909059021 0.984256909059021 0.91827398029051 0.984256909059021
Akr7a5 ENSMUSG00000028743 0.134918787918222 0.202378181877333 0.00570301709613424 0.0171090512884027 0.683927777742414 0.683927777742414
Cda ENSMUSG00000028755 0.681014940808857 0.681014940808857 0.288997842058505 0.681014940808857 0.51883585145554 0.681014940808857
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Hsd17b11 ENSMUSG00000029311 0.514523118108286 0.895045746313367 0.596697164208911 0.895045746313367 0.940220286237586 0.940220286237586
Sdsl ENSMUSG00000029596 0.17553471365084 0.26330207047626 0.00865897532533421 0.0259769259760026 0.896331054405964 0.896331054405964
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Aldh1l1 ENSMUSG00000030088 0.229048950847595 0.682900804653423 0.455267203102282 0.682900804653423 0.83122801457473 0.83122801457473
Adipor2 ENSMUSG00000030168 0.149073323495506 0.447219970486517 0.342273000974822 0.513409501462233 0.649418811184802 0.649418811184802
Stard10 ENSMUSG00000030688 0.464909125763279 0.464909125763279 0.202427011921804 0.464909125763279 0.348826329052893 0.464909125763279
Oat ENSMUSG00000030934 0.719345686105045 0.834222388526471 0.788250737488418 0.834222388526471 0.834222388526471 0.834222388526471
Gpc4 ENSMUSG00000031119 0.646988537048907 0.868349349664235 0.229037508729901 0.687112526189703 0.868349349664235 0.868349349664235
Ebp ENSMUSG00000031168 0.937061311215017 0.937061311215017 0.849714410957955 0.937061311215017 0.599387025174043 0.937061311215017
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Slc25a15 ENSMUSG00000031482 0.462473464931408 0.693710197397112 0.00964805892667311 0.0289441767800193 0.815862876502818 0.815862876502818
Hsd17b2 ENSMUSG00000031844 0.555556494635131 0.833334741952697 0.915039174258537 0.915039174258537 0.368803311338788 0.833334741952697
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Sc5d ENSMUSG00000032018 0.30191068460125 0.905732053803751 0.687186120707919 0.905736195032437 0.905736195032437 0.905736195032437
Bco2 ENSMUSG00000032066 0.51707726074314 0.962225828904045 0.908879484490264 0.962225828904045 0.962225828904045 0.962225828904045
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Dpyd ENSMUSG00000033308 0.572189937160166 0.843566726988339 0.459973133587052 0.843566726988339 0.843566726988339 0.843566726988339
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Nudt15 ENSMUSG00000033405 0.624229072499934 0.912005430630297 0.912005430630297 0.912005430630297 0.663795671858867 0.912005430630297
Dak ENSMUSG00000034371 0.188710542864303 0.283065814296454 0.12510660922972 0.283065814296454 0.749086572223298 0.749086572223298
Entpd8 ENSMUSG00000036813 0.697886732327941 0.704829623547044 0.580733385230905 0.704829623547044 0.704829623547044 0.704829623547044
Vnn1 ENSMUSG00000037440 0.533779748328309 0.867483931239956 0.702651461268161 0.867483931239956 0.867483931239956 0.867483931239956
Inpp4b ENSMUSG00000037940 0.448123106249843 0.672184659374764 0.965369817330894 0.965369817330894 0.305818204710046 0.672184659374764
Dcxr ENSMUSG00000039450 0.0246345216953567 0.07390356508607 0.516931591091901 0.516931591091901 0.384474977311131 0.516931591091901
Mocos ENSMUSG00000039616 0.669692540537422 0.837295546148563 0.837295546148563 0.837295546148563 0.701510555554259 0.837295546148563
Slc44a3 ENSMUSG00000039865 0.879688822592193 0.929531775454951 0.929531775454951 0.929531775454951 0.59229175484251 0.929531775454951
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327
Csgalnact2 ENSMUSG00000042042 0.233565700839995 0.700697102519986 0.797486341970503 0.837382767107545 0.837382767107545 0.837382767107545
Pm20d1 ENSMUSG00000042251 0.38864888581585 0.621434319361342 0.621434319361342 0.621434319361342 0.471745830125479 0.621434319361342
Tnfaip8l1 ENSMUSG00000044469 0.893256473898865 0.893256473898865 0.725343326712531 0.893256473898865 0.655508935508995 0.893256473898865
Isca1 ENSMUSG00000044792 0.556223396090434 0.556223396090434 0.282065707839971 0.556223396090434 0.54831586158242 0.556223396090434
Bdh1 ENSMUSG00000046598 0.55195692926026 0.55195692926026 0.370928296223045 0.55195692926026 0.0520806765559679 0.156242029667904
Gchfr ENSMUSG00000046814 0.262866284409296 0.529222200751923 0.352814800501282 0.529222200751923 0.930792115937423 0.930792115937423
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332
Pdp2 ENSMUSG00000048371 0.641266541293666 0.933941742146841 0.905755491982669 0.933941742146841 0.933941742146841 0.933941742146841
Sephs2 ENSMUSG00000049091 0.629894085323374 0.94484112798506 0.236747218795673 0.71024165638702 0.987400303068685 0.987400303068685
Suox ENSMUSG00000049858 0.908838036234562 0.908838036234562 0.241594122577139 0.724782367731417 0.704608580986811 0.908838036234562
Agmo ENSMUSG00000050103 0.716473171070501 0.716473171070501 0.219775291067659 0.659325873202977 0.529818819327583 0.716473171070501
Sgms2 ENSMUSG00000050931 0.834217238489034 0.834217238489034 0.621629622116372 0.834217238489034 0.770089591493942 0.834217238489034
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Fdps ENSMUSG00000059743 0.494374285256623 0.494374285256623 0.115529537777789 0.346588613333368 0.365425775620161 0.494374285256623
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159
Marc2 ENSMUSG00000073481 0.496668930875465 0.946477702841781 0.722400649086829 0.946477702841781 0.946477702841781 0.946477702841781
Cyp4v3 ENSMUSG00000079057 0.800551083413891 0.883887981693512 0.684285778539267 0.883887981693512 0.883887981693512 0.883887981693512
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Chylomicron assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
P4hb ENSMUSG00000025130 0.728301782383287 0.806656994701942 0.315262721793288 0.806656994701942 0.806656994701942 0.806656994701942
Mttp ENSMUSG00000028158 0.580388257487043 0.870582386230564 0.517174551179467 0.870582386230564 0.883898409450144 0.883898409450144
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Metabolism of vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Cyb5r3 ENSMUSG00000018042 0.365165078617838 0.547747617926757 0.0482094193218234 0.14462825796547 0.601957826226395 0.601957826226395
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Sdc1 ENSMUSG00000020592 0.494320726670871 0.85581086889017 0.85581086889017 0.85581086889017 0.574704078670699 0.85581086889017
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Naprt1 ENSMUSG00000022574 0.332755638894034 0.499133458341051 0.148198924264533 0.444596772793599 0.695924734455875 0.695924734455875
Cyb5 ENSMUSG00000024646 0.728310614186649 0.812784901466279 0.342755071240364 0.812784901466279 0.812784901466279 0.812784901466279
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Aldh1l1 ENSMUSG00000030088 0.229048950847595 0.682900804653423 0.455267203102282 0.682900804653423 0.83122801457473 0.83122801457473
Gpc4 ENSMUSG00000031119 0.646988537048907 0.868349349664235 0.229037508729901 0.687112526189703 0.868349349664235 0.868349349664235
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Bco2 ENSMUSG00000032066 0.51707726074314 0.962225828904045 0.908879484490264 0.962225828904045 0.962225828904045 0.962225828904045
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Vnn1 ENSMUSG00000037440 0.533779748328309 0.867483931239956 0.702651461268161 0.867483931239956 0.867483931239956 0.867483931239956
Mocos ENSMUSG00000039616 0.669692540537422 0.837295546148563 0.837295546148563 0.837295546148563 0.701510555554259 0.837295546148563
Gchfr ENSMUSG00000046814 0.262866284409296 0.529222200751923 0.352814800501282 0.529222200751923 0.930792115937423 0.930792115937423
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159

Biological oxidations

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyb5r3 ENSMUSG00000018042 0.365165078617838 0.547747617926757 0.0482094193218234 0.14462825796547 0.601957826226395 0.601957826226395
Esd ENSMUSG00000021996 0.41774364529658 0.548262366920895 0.548262366920895 0.548262366920895 0.356986281248433 0.548262366920895
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Papss2 ENSMUSG00000024899 0.98425487182645 0.98425487182645 0.621598489016556 0.98425487182645 0.725302103729692 0.98425487182645
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Aadac ENSMUSG00000027761 0.545590012832295 0.573606596756578 0.329528496835431 0.573606596756578 0.573606596756578 0.573606596756578
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Slc35d1 ENSMUSG00000028521 0.62722561410699 0.984256909059021 0.984256909059021 0.984256909059021 0.91827398029051 0.984256909059021
Akr7a5 ENSMUSG00000028743 0.134918787918222 0.202378181877333 0.00570301709613424 0.0171090512884027 0.683927777742414 0.683927777742414
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Marc2 ENSMUSG00000073481 0.496668930875465 0.946477702841781 0.722400649086829 0.946477702841781 0.946477702841781 0.946477702841781
Cyp4v3 ENSMUSG00000079057 0.800551083413891 0.883887981693512 0.684285778539267 0.883887981693512 0.883887981693512 0.883887981693512
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Plasma lipoprotein assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
P4hb ENSMUSG00000025130 0.728301782383287 0.806656994701942 0.315262721793288 0.806656994701942 0.806656994701942 0.806656994701942
Mttp ENSMUSG00000028158 0.580388257487043 0.870582386230564 0.517174551179467 0.870582386230564 0.883898409450144 0.883898409450144
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Protein localization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Cyb5 ENSMUSG00000024646 0.728310614186649 0.812784901466279 0.342755071240364 0.812784901466279 0.812784901466279 0.812784901466279
Idh1 ENSMUSG00000025950 0.930785313007059 0.930785313007059 0.522126117800768 0.930785313007059 0.890138019381563 0.930785313007059
Hspd1 ENSMUSG00000025980 0.728323292003661 0.846654044229552 0.205346085981935 0.616038257945806 0.846654044229552 0.846654044229552
Pex16 ENSMUSG00000027222 0.038223126595876 0.114669379787628 0.264563891892219 0.396845837838329 0.596705985390053 0.596705985390053
Abcd3 ENSMUSG00000028127 0.5352345679375 0.616025305519346 0.109214676435002 0.327644029305005 0.616025305519346 0.616025305519346
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159

Retinoid metabolism and transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Sdc1 ENSMUSG00000020592 0.494320726670871 0.85581086889017 0.85581086889017 0.85581086889017 0.574704078670699 0.85581086889017
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Gpc4 ENSMUSG00000031119 0.646988537048907 0.868349349664235 0.229037508729901 0.687112526189703 0.868349349664235 0.868349349664235
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Bco2 ENSMUSG00000032066 0.51707726074314 0.962225828904045 0.908879484490264 0.962225828904045 0.962225828904045 0.962225828904045
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Plasma lipoprotein assembly, remodeling, and clearance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Soat2 ENSMUSG00000023045 0.0288517213191708 0.0865551639575124 0.993642942871853 0.993642942871853 0.622111525047928 0.933167287571893
P4hb ENSMUSG00000025130 0.728301782383287 0.806656994701942 0.315262721793288 0.806656994701942 0.806656994701942 0.806656994701942
Mttp ENSMUSG00000028158 0.580388257487043 0.870582386230564 0.517174551179467 0.870582386230564 0.883898409450144 0.883898409450144
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Pcsk9 ENSMUSG00000044254 0.717660369466232 0.904695357599178 0.904695357599178 0.904695357599178 0.807569359073865 0.904695357599178
Lipg ENSMUSG00000053846 0.791101575304333 0.958989163598133 0.7099296795158 0.958989163598133 0.958989163598133 0.958989163598133

ABC transporters in lipid homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Abcg8 ENSMUSG00000024254 0.911935191938652 0.914719077172943 0.756659424748474 0.914719077172943 0.914719077172943 0.914719077172943
Abcd3 ENSMUSG00000028127 0.5352345679375 0.616025305519346 0.109214676435002 0.327644029305005 0.616025305519346 0.616025305519346
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Abcg5 ENSMUSG00000040505 0.599474040803033 0.821583333391364 0.821583333391364 0.821583333391364 0.576873686324377 0.821583333391364
Abca9 ENSMUSG00000041797 0.303846769149494 0.371742134298637 0.371742134298637 0.371742134298637 0.098901026209402 0.296703078628206

Metabolism of fat-soluble vitamins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Sdc1 ENSMUSG00000020592 0.494320726670871 0.85581086889017 0.85581086889017 0.85581086889017 0.574704078670699 0.85581086889017
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Gpc4 ENSMUSG00000031119 0.646988537048907 0.868349349664235 0.229037508729901 0.687112526189703 0.868349349664235 0.868349349664235
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Bco2 ENSMUSG00000032066 0.51707726074314 0.962225828904045 0.908879484490264 0.962225828904045 0.962225828904045 0.962225828904045
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Peroxisomal lipid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159

Urea cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Slc25a15 ENSMUSG00000031482 0.462473464931408 0.693710197397112 0.00964805892667311 0.0289441767800193 0.815862876502818 0.815862876502818
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332

Metabolism of amino acids and derivatives

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prodh ENSMUSG00000003526 0.202510508628617 0.607531525885852 0.828130885548806 0.902623894024535 0.902623894024535 0.902623894024535
Chdh ENSMUSG00000015970 0.949595160247374 0.949595160247374 0.946459933959203 0.949595160247374 0.868195875331811 0.949595160247374
Iyd ENSMUSG00000019762 0.904992273441103 0.904992273441103 0.848170897654359 0.904992273441103 0.43603284409895 0.904992273441103
Pcbd1 ENSMUSG00000020098 0.429376538640888 0.686461294346774 0.457640862897849 0.686461294346774 0.69590355919032 0.69590355919032
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Gpt ENSMUSG00000022546 0.187316349622097 0.280974524433145 0.0745407773777358 0.223622332133207 0.452719413290398 0.452719413290398
Slc25a10 ENSMUSG00000025792 0.283440017805979 0.715358573142372 0.476905715428248 0.715358573142372 0.97480422348121 0.97480422348121
Cps1 ENSMUSG00000025991 0.52267398391391 0.996829893538467 0.996829893538467 0.996829893538467 0.679811318304144 0.996829893538467
Slc25a12 ENSMUSG00000027010 0.569560069233245 0.704718632962594 0.672675741842173 0.704718632962594 0.704718632962594 0.704718632962594
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Sdsl ENSMUSG00000029596 0.17553471365084 0.26330207047626 0.00865897532533421 0.0259769259760026 0.896331054405964 0.896331054405964
Oat ENSMUSG00000030934 0.719345686105045 0.834222388526471 0.788250737488418 0.834222388526471 0.834222388526471 0.834222388526471
Otc ENSMUSG00000031173 0.681269113306356 0.681269113306356 0.465570383407725 0.681269113306356 0.231585146130196 0.681269113306356
Slc25a15 ENSMUSG00000031482 0.462473464931408 0.693710197397112 0.00964805892667311 0.0289441767800193 0.815862876502818 0.815862876502818
Nags ENSMUSG00000048217 0.66760916686236 0.76475345664332 0.176102001741253 0.528306005223758 0.76475345664332 0.76475345664332
Sephs2 ENSMUSG00000049091 0.629894085323374 0.94484112798506 0.236747218795673 0.71024165638702 0.987400303068685 0.987400303068685
Suox ENSMUSG00000049858 0.908838036234562 0.908838036234562 0.241594122577139 0.724782367731417 0.704608580986811 0.908838036234562

Chylomicron remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595

Beta-oxidation of very long chain fatty acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159

VLDL assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
P4hb ENSMUSG00000025130 0.728301782383287 0.806656994701942 0.315262721793288 0.806656994701942 0.806656994701942 0.806656994701942
Mttp ENSMUSG00000028158 0.580388257487043 0.870582386230564 0.517174551179467 0.870582386230564 0.883898409450144 0.883898409450144

Visual phototransduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Sdc1 ENSMUSG00000020592 0.494320726670871 0.85581086889017 0.85581086889017 0.85581086889017 0.574704078670699 0.85581086889017
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Gpc4 ENSMUSG00000031119 0.646988537048907 0.868349349664235 0.229037508729901 0.687112526189703 0.868349349664235 0.868349349664235
Bcmo1 ENSMUSG00000031845 0.742150610846683 0.742150610846683 0.296555235560685 0.742150610846683 0.510186862482583 0.742150610846683
Bco2 ENSMUSG00000032066 0.51707726074314 0.962225828904045 0.908879484490264 0.962225828904045 0.962225828904045 0.962225828904045
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Cyp4v3 ENSMUSG00000079057 0.800551083413891 0.883887981693512 0.684285778539267 0.883887981693512 0.883887981693512 0.883887981693512

Plasma lipoprotein remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apob ENSMUSG00000020609 0.534758150634597 0.534758150634597 0.39207792834889 0.534758150634597 0.432034500428695 0.534758150634597
Apoa4 ENSMUSG00000032080 0.626592893498284 0.626592893498284 0.339491104381808 0.5682109227497 0.378807281833133 0.5682109227497
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Lipg ENSMUSG00000053846 0.791101575304333 0.958989163598133 0.7099296795158 0.958989163598133 0.958989163598133 0.958989163598133

Phase I - Functionalization of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyb5r3 ENSMUSG00000018042 0.365165078617838 0.547747617926757 0.0482094193218234 0.14462825796547 0.601957826226395 0.601957826226395
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Aadac ENSMUSG00000027761 0.545590012832295 0.573606596756578 0.329528496835431 0.573606596756578 0.573606596756578 0.573606596756578
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Marc2 ENSMUSG00000073481 0.496668930875465 0.946477702841781 0.722400649086829 0.946477702841781 0.946477702841781 0.946477702841781
Cyp4v3 ENSMUSG00000079057 0.800551083413891 0.883887981693512 0.684285778539267 0.883887981693512 0.883887981693512 0.883887981693512

Metabolism of lipids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Acsf3 ENSMUSG00000015016 0.00553114097232579 0.0123128247998871 0.0082085498665914 0.0123128247998871 0.984232074463724 0.984232074463724
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Gyk ENSMUSG00000025059 0.99685090403113 0.99685090403113 0.896329983018513 0.99685090403113 0.566728186207889 0.99685090403113
Dbi ENSMUSG00000026385 0.537837801858057 0.94650693842806 0.94650693842806 0.94650693842806 0.63283743275398 0.94650693842806
Hsd17b7 ENSMUSG00000026675 0.211045912909335 0.633137738728006 0.675492049788387 0.675492049788387 0.661090689138681 0.675492049788387
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Hsd17b11 ENSMUSG00000029311 0.514523118108286 0.895045746313367 0.596697164208911 0.895045746313367 0.940220286237586 0.940220286237586
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Stard10 ENSMUSG00000030688 0.464909125763279 0.464909125763279 0.202427011921804 0.464909125763279 0.348826329052893 0.464909125763279
Ebp ENSMUSG00000031168 0.937061311215017 0.937061311215017 0.849714410957955 0.937061311215017 0.599387025174043 0.937061311215017
Hsd17b2 ENSMUSG00000031844 0.555556494635131 0.833334741952697 0.915039174258537 0.915039174258537 0.368803311338788 0.833334741952697
Sc5d ENSMUSG00000032018 0.30191068460125 0.905732053803751 0.687186120707919 0.905736195032437 0.905736195032437 0.905736195032437
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Inpp4b ENSMUSG00000037940 0.448123106249843 0.672184659374764 0.965369817330894 0.965369817330894 0.305818204710046 0.672184659374764
Slc44a3 ENSMUSG00000039865 0.879688822592193 0.929531775454951 0.929531775454951 0.929531775454951 0.59229175484251 0.929531775454951
Tnfaip8l1 ENSMUSG00000044469 0.893256473898865 0.893256473898865 0.725343326712531 0.893256473898865 0.655508935508995 0.893256473898865
Bdh1 ENSMUSG00000046598 0.55195692926026 0.55195692926026 0.370928296223045 0.55195692926026 0.0520806765559679 0.156242029667904
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Agmo ENSMUSG00000050103 0.716473171070501 0.716473171070501 0.219775291067659 0.659325873202977 0.529818819327583 0.716473171070501
Sgms2 ENSMUSG00000050931 0.834217238489034 0.834217238489034 0.621629622116372 0.834217238489034 0.770089591493942 0.834217238489034
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Fdps ENSMUSG00000059743 0.494374285256623 0.494374285256623 0.115529537777789 0.346588613333368 0.365425775620161 0.494374285256623

Phase II - Conjugation of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Esd ENSMUSG00000021996 0.41774364529658 0.548262366920895 0.548262366920895 0.548262366920895 0.356986281248433 0.548262366920895
Papss2 ENSMUSG00000024899 0.98425487182645 0.98425487182645 0.621598489016556 0.98425487182645 0.725302103729692 0.98425487182645
Gss ENSMUSG00000027610 0.946511005407269 0.946511005407269 0.661245146568485 0.946511005407269 0.450533844038254 0.946511005407269
Slc35d1 ENSMUSG00000028521 0.62722561410699 0.984256909059021 0.984256909059021 0.984256909059021 0.91827398029051 0.984256909059021
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Gstt2 ENSMUSG00000033318 0.133161178449644 0.399483535348933 0.868342824180517 0.868342824180517 0.479528257840993 0.71929238676149
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Fatty acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crot ENSMUSG00000003623 0.818918959718378 0.818918959718378 0.530031240271851 0.818918959718378 0.743194289134068 0.818918959718378
Aldh3a2 ENSMUSG00000010025 0.911873654432194 0.962197191301961 0.962197191301961 0.962197191301961 0.658098323842503 0.962197191301961
Acsf3 ENSMUSG00000015016 0.00553114097232579 0.0123128247998871 0.0082085498665914 0.0123128247998871 0.984232074463724 0.984232074463724
Acox1 ENSMUSG00000020777 0.740182656479861 0.740182656479861 0.399842124598158 0.740182656479861 0.684215277350826 0.740182656479861
Ehhadh ENSMUSG00000022853 0.0855350897284085 0.256605269185226 0.68719899563583 0.68719899563583 0.445571831551768 0.668357747327653
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Hsd17b4 ENSMUSG00000024507 0.707625906815405 0.740179886628675 0.0524931863557144 0.157479559067143 0.740179886628675 0.740179886628675
Dbi ENSMUSG00000026385 0.537837801858057 0.94650693842806 0.94650693842806 0.94650693842806 0.63283743275398 0.94650693842806
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Acot4 ENSMUSG00000052392 0.599307475163167 0.918244796442159 0.840355840999389 0.918244796442159 0.918244796442159 0.918244796442159
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182

HDL remodeling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apoc2 ENSMUSG00000002992 0.724013246411304 0.774947914392445 0.709725498471061 0.774947914392445 0.774947914392445 0.774947914392445
Apoa1 ENSMUSG00000032083 0.59566836516123 0.852574745842595 0.553111183704634 0.852574745842595 0.852574745842595 0.852574745842595
Lipg ENSMUSG00000053846 0.791101575304333 0.958989163598133 0.7099296795158 0.958989163598133 0.958989163598133 0.958989163598133

Metabolism of water-soluble vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyb5r3 ENSMUSG00000018042 0.365165078617838 0.547747617926757 0.0482094193218234 0.14462825796547 0.601957826226395 0.601957826226395
Shmt1 ENSMUSG00000020534 0.800575242471811 0.896374918195745 0.896374918195745 0.896374918195745 0.701791873488321 0.896374918195745
Naprt1 ENSMUSG00000022574 0.332755638894034 0.499133458341051 0.148198924264533 0.444596772793599 0.695924734455875 0.695924734455875
Cyb5 ENSMUSG00000024646 0.728310614186649 0.812784901466279 0.342755071240364 0.812784901466279 0.812784901466279 0.812784901466279
Aldh1l1 ENSMUSG00000030088 0.229048950847595 0.682900804653423 0.455267203102282 0.682900804653423 0.83122801457473 0.83122801457473
Pccb ENSMUSG00000032527 0.0392585327607326 0.102614202943263 0.0684094686288419 0.102614202943263 0.751975589162666 0.751975589162666
Vnn1 ENSMUSG00000037440 0.533779748328309 0.867483931239956 0.702651461268161 0.867483931239956 0.867483931239956 0.867483931239956
Mocos ENSMUSG00000039616 0.669692540537422 0.837295546148563 0.837295546148563 0.837295546148563 0.701510555554259 0.837295546148563
Mocs1 ENSMUSG00000064120 0.138150082395834 0.414450247187501 0.298381848848078 0.447572773272118 0.54554248454159 0.54554248454159

Glucuronidation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc35d1 ENSMUSG00000028521 0.62722561410699 0.984256909059021 0.984256909059021 0.984256909059021 0.91827398029051 0.984256909059021
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412
Ugt2b34 ENSMUSG00000029260 0.463215183505213 0.961094406506137 0.961094406506137 0.961094406506137 0.860972458712394 0.961094406506137
Ugt1a1 ENSMUSG00000089960 0.945758869463502 0.945758869463502 0.923442965583948 0.945758869463502 0.772676634872895 0.945758869463502

Cytochrome P450 - arranged by substrate type

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4f14 ENSMUSG00000024292 0.764069890831284 0.946487407588615 0.767174444177854 0.946487407588615 0.946487407588615 0.946487407588615
Cyp2u1 ENSMUSG00000027983 0.921383775092204 0.921383775092204 0.294592129360224 0.870518015760738 0.580345343840492 0.870518015760738
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Nr1h4 ENSMUSG00000047638 0.721169761556175 0.721169761556175 0.179634714705066 0.519807201450866 0.346538134300577 0.519807201450866
Cyp2j6 ENSMUSG00000052914 0.98425549591182 0.98425549591182 0.460089152854634 0.98425549591182 0.962225268338433 0.98425549591182
Cyp4v3 ENSMUSG00000079057 0.800551083413891 0.883887981693512 0.684285778539267 0.883887981693512 0.883887981693512 0.883887981693512

Formation of the active cofactor, UDP-glucuronate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc35d1 ENSMUSG00000028521 0.62722561410699 0.984256909059021 0.984256909059021 0.984256909059021 0.91827398029051 0.984256909059021
Ugdh ENSMUSG00000029201 0.228904141891331 0.686117402381068 0.457411601587378 0.686117402381068 0.952787756803412 0.952787756803412

Fructose catabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aldob ENSMUSG00000028307 0.572304878861035 0.981106543463403 0.749154569387916 0.981106543463403 0.981106543463403 0.981106543463403
Dak ENSMUSG00000034371 0.188710542864303 0.283065814296454 0.12510660922972 0.283065814296454 0.749086572223298 0.749086572223298

Aflatoxin activation and detoxification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr7a5 ENSMUSG00000028743 0.134918787918222 0.202378181877333 0.00570301709613424 0.0171090512884027 0.683927777742414 0.683927777742414
Cyp3a25 ENSMUSG00000029630 0.580871400177719 0.580871400177719 0.143824593172432 0.222242030866052 0.148161353910702 0.222242030866052
Cyp3a13 ENSMUSG00000029727 0.616694503121477 0.708547248021032 0.64352164170239 0.708547248021032 0.708547248021032 0.708547248021032
Ggt6 ENSMUSG00000040471 0.472936714395327 0.472936714395327 0.446408176897186 0.472936714395327 0.313085931645231 0.472936714395327

Degradation of cysteine and homocysteine

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc25a10 ENSMUSG00000025792 0.283440017805979 0.715358573142372 0.476905715428248 0.715358573142372 0.97480422348121 0.97480422348121
Cth ENSMUSG00000028179 0.298312470506278 0.566655376780565 0.545452063129505 0.566655376780565 0.566655376780565 0.566655376780565
Suox ENSMUSG00000049858 0.908838036234562 0.908838036234562 0.241594122577139 0.724782367731417 0.704608580986811 0.908838036234562

skyblue3

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mybpc3 ENSMUSG00000002100 0.742069063561577 0.742069063561577 0.373807007016675 0.742069063561577 0.642026607669292 0.742069063561577
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Cardiac muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Casq2 ENSMUSG00000027861 0.877519646545918 0.959015714741772 0.959015714741772 0.959015714741772 0.924466053452195 0.959015714741772
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Hypertrophic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mybpc3 ENSMUSG00000002100 0.742069063561577 0.742069063561577 0.373807007016675 0.742069063561577 0.642026607669292 0.742069063561577
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Adrenergic signaling in cardiomyocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Scn5a ENSMUSG00000032511 0.916375776895484 0.916375776895484 0.471295830959376 0.916375776895484 0.897140563763909 0.916375776895484
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Calcium signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Casq2 ENSMUSG00000027861 0.877519646545918 0.959015714741772 0.959015714741772 0.959015714741772 0.924466053452195 0.959015714741772
Fgf16 ENSMUSG00000031230 0.844959131489684 0.844959131489684 0.636001205218534 0.844959131489684 0.649141977512161 0.844959131489684
Ednra ENSMUSG00000031616 0.862108111145099 0.862108111145099 0.300183876361191 0.450275814541786 0.274949523464459 0.450275814541786
Mylk3 ENSMUSG00000031698 0.581511267829256 0.581511267829256 0.232557619279372 0.348836428919058 0.226548637837944 0.348836428919058
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Apelin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Gnb3 ENSMUSG00000023439 0.955422223378118 0.955422223378118 0.800812900715048 0.955422223378118 0.845136724806541 0.955422223378118
Mylk3 ENSMUSG00000031698 0.581511267829256 0.581511267829256 0.232557619279372 0.348836428919058 0.226548637837944 0.348836428919058
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903

cGMP-PKG signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ednra ENSMUSG00000031616 0.862108111145099 0.862108111145099 0.300183876361191 0.450275814541786 0.274949523464459 0.450275814541786
Mylk3 ENSMUSG00000031698 0.581511267829256 0.581511267829256 0.232557619279372 0.348836428919058 0.226548637837944 0.348836428919058
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821

Muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Corin ENSMUSG00000005220 0.750625549147181 0.750625549147181 0.435604136765753 0.653406205148629 0.396889781892922 0.653406205148629
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Casq2 ENSMUSG00000027861 0.877519646545918 0.959015714741772 0.959015714741772 0.959015714741772 0.924466053452195 0.959015714741772
Scn5a ENSMUSG00000032511 0.916375776895484 0.916375776895484 0.471295830959376 0.916375776895484 0.897140563763909 0.916375776895484
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Striated Muscle Contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Myl2 ENSMUSG00000013936 0.260706724268104 0.260706724268104 0.191771776397606 0.260706724268104 0.239466965314569 0.260706724268104
Tnnt2 ENSMUSG00000026414 0.886993865016995 0.940220992546817 0.87141143131258 0.940220992546817 0.940220992546817 0.940220992546817
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Myh6 ENSMUSG00000040752 0.870734274341372 0.870734274341372 0.305656439302081 0.497707143394821 0.331804762263214 0.497707143394821
Myl3 ENSMUSG00000059741 0.540006203534953 0.540006203534953 0.0510973505473351 0.153292051642005 0.261059850544602 0.391589775816903
Actc1 ENSMUSG00000068614 0.619940655405529 0.619940655405529 0.00351565008150738 0.0105469502445221 0.390194900224664 0.585292350336996
Tnnc1 ENSMUSG00000091898 0.940043638878277 0.952715645940502 0.461135818929286 0.952715645940502 0.952715645940502 0.952715645940502

Cardiac conduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Corin ENSMUSG00000005220 0.750625549147181 0.750625549147181 0.435604136765753 0.653406205148629 0.396889781892922 0.653406205148629
Casq2 ENSMUSG00000027861 0.877519646545918 0.959015714741772 0.959015714741772 0.959015714741772 0.924466053452195 0.959015714741772
Scn5a ENSMUSG00000032511 0.916375776895484 0.916375776895484 0.471295830959376 0.916375776895484 0.897140563763909 0.916375776895484
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752

Ion homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Casq2 ENSMUSG00000027861 0.877519646545918 0.959015714741772 0.959015714741772 0.959015714741772 0.924466053452195 0.959015714741772
Tnni3 ENSMUSG00000035458 0.561313582924992 0.841970374387487 0.350763300509878 0.841970374387487 0.971642163573169 0.971642163573169
Pln ENSMUSG00000038583 0.828092947931752 0.828092947931752 0.606996025253451 0.828092947931752 0.806314850226639 0.828092947931752

turquoise

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sema4f ENSMUSG00000000627 0.416909920139522 0.764215472029008 0.764215472029008 0.764215472029008 0.694473729498833 0.764215472029008
Sema6b ENSMUSG00000001227 0.386779549413037 0.580169324119555 0.227476717616854 0.580169324119555 0.930796033268225 0.930796033268225
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Pard6a ENSMUSG00000005699 0.540333259339338 0.540333259339338 0.17301166015541 0.519034980466231 0.48199026875276 0.540333259339338
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Srgap1 ENSMUSG00000020121 0.681329235475121 0.977953356810363 0.977953356810363 0.977953356810363 0.776212266960857 0.977953356810363
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Boc ENSMUSG00000022687 0.849735390372532 0.849735390372532 0.424794906992154 0.637192360488232 0.330824113689029 0.637192360488232
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Robo1 ENSMUSG00000022883 0.535140615425727 0.7573725568853 0.7573725568853 0.7573725568853 0.300455283086251 0.7573725568853
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Myl12a ENSMUSG00000024048 0.893235036387356 0.893235036387356 0.564169435197058 0.846254152795587 0.506984599890042 0.846254152795587
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Slit1 ENSMUSG00000025020 0.766558896398946 0.797515483245119 0.736551305289254 0.797515483245119 0.797515483245119 0.797515483245119
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Unc5a ENSMUSG00000025876 0.812552222144865 0.812552222144865 0.767074155135085 0.812552222144865 0.704363534681499 0.812552222144865
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Srgap2 ENSMUSG00000026425 0.899497345001215 0.971666102581328 0.971666102581328 0.971666102581328 0.404374468413579 0.971666102581328
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Trpc3 ENSMUSG00000027716 0.506935424866727 0.76040313730009 0.32296198461377 0.76040313730009 0.80667193803308 0.80667193803308
Trpc4 ENSMUSG00000027748 0.767576880979932 0.888006864533746 0.888006864533746 0.888006864533746 0.815818518453809 0.888006864533746
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Ablim2 ENSMUSG00000029095 0.911983022587343 0.911983022587343 0.862136663596688 0.911983022587343 0.890101240952769 0.911983022587343
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Srgap3 ENSMUSG00000030257 0.896343344184652 0.896343344184652 0.821943425826632 0.896343344184652 0.596622632987284 0.896343344184652
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Plxnb3 ENSMUSG00000031385 0.858919312754963 0.858919312754963 0.311087152421553 0.661320759556636 0.44088050637109 0.661320759556636
L1cam ENSMUSG00000031391 0.698816829578787 0.782281595099861 0.731289141683251 0.782281595099861 0.782281595099861 0.782281595099861
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Slit2 ENSMUSG00000031558 0.687185789711974 0.930806648357942 0.930806648357942 0.930806648357942 0.890126121650186 0.930806648357942
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Robo3 ENSMUSG00000032128 0.968290756351216 0.974625340821463 0.974625340821463 0.974625340821463 0.772923417273521 0.974625340821463
Neo1 ENSMUSG00000032340 0.815843386285531 0.815843386285531 0.479539413144783 0.815843386285531 0.664079307565856 0.815843386285531
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Ablim3 ENSMUSG00000032735 0.52482890455904 0.649812636234061 0.649812636234061 0.649812636234061 0.566875256636599 0.649812636234061
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Sema6c ENSMUSG00000038777 0.529940231136058 0.675490647130333 0.675490647130333 0.675490647130333 0.371751184237196 0.675490647130333
Pak7 ENSMUSG00000039913 0.594969319883574 0.948939766320461 0.881149414868131 0.948939766320461 0.948939766320461 0.948939766320461
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Lrrc4 ENSMUSG00000049939 0.958742342237885 0.958742342237885 0.722693425151927 0.958742342237885 0.799954758249415 0.958742342237885
Lrrc4c ENSMUSG00000050587 0.663875578660822 0.874428669298983 0.821948238070675 0.874428669298983 0.874428669298983 0.874428669298983
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Sema5b ENSMUSG00000052133 0.8652255403839 0.949625150311005 0.672591225673965 0.949625150311005 0.949625150311005 0.949625150311005
Bmpr1b ENSMUSG00000052430 0.393561355374609 0.833976643466496 0.833976643466496 0.833976643466496 0.809125982247177 0.833976643466496
Epha3 ENSMUSG00000052504 0.778133253874654 0.817231877187333 0.817231877187333 0.817231877187333 0.190810646220279 0.572431938660837
Robo2 ENSMUSG00000052516 0.681395723687699 0.859032422828999 0.859032422828999 0.859032422828999 0.737235705003007 0.859032422828999
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rnd1 ENSMUSG00000054855 0.661203233113187 0.661203233113187 0.298379466146235 0.661203233113187 0.627172996382542 0.661203233113187
Pard6g ENSMUSG00000056214 0.215469229904447 0.646407689713342 0.644138180114681 0.655513687932582 0.655513687932582 0.655513687932582
Slit3 ENSMUSG00000056427 0.89318101208312 0.918220401047043 0.704618619398227 0.918220401047043 0.918220401047043 0.918220401047043
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Ntng1 ENSMUSG00000059857 0.926534171334259 0.926534171334259 0.910073513352151 0.926534171334259 0.850476861484157 0.926534171334259
Unc5c ENSMUSG00000059921 0.675253233838164 0.845582170384226 0.811530211365191 0.845582170384226 0.845582170384226 0.845582170384226
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sema3e ENSMUSG00000063531 0.667952496734551 0.700802645980391 0.700802645980391 0.700802645980391 0.583640050957042 0.700802645980391
Unc5d ENSMUSG00000063626 0.891196396490525 0.891196396490525 0.460857789726919 0.691286684590379 0.432731701368856 0.691286684590379
Bmpr2 ENSMUSG00000067336 0.0957463246096653 0.287238973828996 0.399928403336969 0.599892605005454 0.987404529604506 0.987404529604506
Rgma ENSMUSG00000070509 0.908882462450851 0.908882462450851 0.874562391952601 0.908882462450851 0.494410400030678 0.908882462450851
Pak6 ENSMUSG00000074923 0.320780926597679 0.898839487095189 0.599226324730126 0.898839487095189 0.96534841382286 0.96534841382286

Glutamatergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Dlgap1 ENSMUSG00000003279 0.914181497561351 0.914181497561351 0.62518185785014 0.914181497561351 0.694130083855431 0.914181497561351
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Homer1 ENSMUSG00000007617 0.317201338024321 0.943369538436606 0.943369538436606 0.943369538436606 0.797512319691107 0.943369538436606
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Grm8 ENSMUSG00000024211 0.581459279843197 0.863797416908078 0.863797416908078 0.863797416908078 0.746413291246183 0.863797416908078
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Homer2 ENSMUSG00000025813 0.509499642036776 0.918259619702903 0.918259619702903 0.918259619702903 0.661172737615778 0.918259619702903
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Glul ENSMUSG00000026473 0.56159503256356 0.710595323259519 0.285656307463184 0.710595323259519 0.710595323259519 0.710595323259519
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Slc17a6 ENSMUSG00000030500 0.795756816312547 0.887473643997066 0.828388736158169 0.887473643997066 0.887473643997066 0.887473643997066
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Shank2 ENSMUSG00000037541 0.794349094947865 0.794349094947865 0.757514923991936 0.794349094947865 0.75449015233661 0.794349094947865
Shank1 ENSMUSG00000038738 0.517084919638398 0.845614104820268 0.793854460752608 0.845614104820268 0.845614104820268 0.845614104820268
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Grm7 ENSMUSG00000056755 0.858717824204382 0.977471956051544 0.625073995050131 0.977471956051544 0.977471956051544 0.977471956051544
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Grm4 ENSMUSG00000063239 0.758607855990508 0.89041686450784 0.89041686450784 0.89041686450784 0.819454188821776 0.89041686450784
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Circadian entrainment

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Per1 ENSMUSG00000020893 0.000541797521443416 0.00162539256433025 0.382394047682372 0.573591071523558 0.952787619873185 0.952787619873185
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Per3 ENSMUSG00000028957 0.233611626275099 0.350417439412648 0.0282904234650245 0.0848712703950736 0.821967874241668 0.821967874241668
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Nos1ap ENSMUSG00000038473 0.987404300377633 1 0.905747950611713 1 1 1
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Rasd1 ENSMUSG00000049892 0.367780254397946 0.733159755472243 0.733159755472243 0.733159755472243 0.558203411510132 0.733159755472243
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

cAMP signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sox9 ENSMUSG00000000567 0.955918424514663 0.955918424514663 0.821846883401704 0.955918424514663 0.89320544824663 0.955918424514663
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tiam1 ENSMUSG00000002489 0.990553275376873 0.990553275376873 0.794483074638216 0.990553275376873 0.743187703036167 0.990553275376873
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Vipr2 ENSMUSG00000011171 0.81442795927062 0.81442795927062 0.274336900623371 0.670413060812143 0.446942040541429 0.670413060812143
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Vip ENSMUSG00000019772 0.334662694857406 0.798906412142223 0.532604274761482 0.798906412142223 0.980663464337666 0.980663464337666
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Hcn2 ENSMUSG00000020331 0.534981328000019 0.577729520726797 0.283774858742742 0.577729520726797 0.577729520726797 0.577729520726797
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Tshr ENSMUSG00000020963 0.749652680700576 0.917286863864632 0.00541113501137084 0.0162334050341125 0.917286863864632 0.917286863864632
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Pde10a ENSMUSG00000023868 0.41714785599035 0.764255216098399 0.962160233881058 0.962160233881058 0.509503477398933 0.764255216098399
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Gipr ENSMUSG00000030406 0.818861357220811 0.910855665291448 0.910855665291448 0.910855665291448 0.840617980437171 0.910855665291448
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Cnga4 ENSMUSG00000030897 0.186199731629399 0.279299597444098 0.466165544799658 0.466165544799658 0.101073112177992 0.279299597444098
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Hcn4 ENSMUSG00000032338 0.443454103242053 0.952585035070339 0.933630870552189 0.952585035070339 0.952585035070339 0.952585035070339
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Amh ENSMUSG00000035262 0.781245551097063 0.781245551097063 0.282261166367888 0.781245551097063 0.739436278785459 0.781245551097063
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Sstr1 ENSMUSG00000035431 0.406238592066445 0.964057292265133 0.964057292265133 0.964057292265133 0.783863340301641 0.964057292265133
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Npy1r ENSMUSG00000036437 0.404299171034672 0.952738532723292 0.952738532723292 0.952738532723292 0.911889505521477 0.952738532723292
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

GABAergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.844114356552196 0.947775956497703 0.699199242656938 0.947775956497703 0.947775956497703 0.947775956497703
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Hap1 ENSMUSG00000006930 0.761137758535261 0.993701086721283 0.993701086721283 0.993701086721283 0.915140925930742 0.993701086721283
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Slc12a5 ENSMUSG00000017740 0.996851063664395 0.996851063664395 0.251175722824672 0.753527168474017 0.599246759979626 0.898870139969439
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Glul ENSMUSG00000026473 0.56159503256356 0.710595323259519 0.285656307463184 0.710595323259519 0.710595323259519 0.710595323259519
Gad2 ENSMUSG00000026787 0.62440231835418 0.88663582819218 0.698820798936253 0.88663582819218 0.88663582819218 0.88663582819218
Gabrd ENSMUSG00000029054 0.423111511865783 0.634667267798675 0.0760107699773406 0.228032309932022 0.663543952203221 0.663543952203221
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Gabarapl1 ENSMUSG00000030161 0.535140432761299 0.535140432761299 0.194167648861091 0.535140432761299 0.450381081843525 0.535140432761299
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gabarapl2 ENSMUSG00000031950 0.224363901485535 0.427080118991053 0.382427620187507 0.427080118991053 0.427080118991053 0.427080118991053
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Plcl1 ENSMUSG00000038349 0.519714632162887 0.968520293365563 0.949648844458141 0.968520293365563 0.968520293365563 0.968520293365563
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Gphn ENSMUSG00000047454 0.800500098191337 1 0.664069758876297 1 1 1
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gad1 ENSMUSG00000070880 0.768676916415066 0.936959438615519 0.936959438615519 0.936959438615519 0.829955651614648 0.936959438615519
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Dopaminergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Th ENSMUSG00000000214 0.781258243079159 0.963513647581858 0.944303840944202 0.963513647581858 0.963513647581858 0.963513647581858
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Ppp2r2b ENSMUSG00000024500 0.949603809902928 0.949603809902928 0.779000669719215 0.949603809902928 0.716077271725534 0.949603809902928
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Caly ENSMUSG00000025468 0.936527654657815 0.939739308500895 0.772233790675969 0.939739308500895 0.939739308500895 0.939739308500895
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Kif5c ENSMUSG00000026764 0.524835301545644 0.824923056977493 0.824923056977493 0.824923056977493 0.684013828925298 0.824923056977493
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Ppp2r2c ENSMUSG00000029120 0.677925381424787 0.774758437583038 0.676212341554018 0.774758437583038 0.774758437583038 0.774758437583038
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Ppp2r2d ENSMUSG00000041769 0.737196580003877 0.740175941536255 0.411163215713724 0.740175941536255 0.740175941536255 0.740175941536255
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Scn1a ENSMUSG00000064329 0.228565863853541 0.685697591560622 0.554070895749723 0.744924725900363 0.744924725900363 0.744924725900363
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Kif5a ENSMUSG00000074657 0.968501666827124 0.968501666827124 0.758149741930825 0.968501666827124 0.646684223292294 0.968501666827124
Tomt ENSMUSG00000078630 0.702003199818379 0.837360622354244 0.837360622354244 0.837360622354244 0.683928196153426 0.837360622354244
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Morphine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.844114356552196 0.947775956497703 0.699199242656938 0.947775956497703 0.947775956497703 0.947775956497703
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Pde7b ENSMUSG00000019990 0.937081114683675 0.937081114683675 0.641303214236346 0.937081114683675 0.666946639848943 0.937081114683675
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Pde8b ENSMUSG00000021684 0.588529561107146 0.843506900088092 0.644018455010028 0.843506900088092 0.843506900088092 0.843506900088092
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Pde10a ENSMUSG00000023868 0.41714785599035 0.764255216098399 0.962160233881058 0.962160233881058 0.509503477398933 0.764255216098399
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gabrd ENSMUSG00000029054 0.423111511865783 0.634667267798675 0.0760107699773406 0.228032309932022 0.663543952203221 0.663543952203221
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Pde11a ENSMUSG00000075270 0.54212265120549 0.886803769999323 0.740010141364011 0.886803769999323 0.886803769999323 0.886803769999323
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Nicotine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.844114356552196 0.947775956497703 0.699199242656938 0.947775956497703 0.947775956497703 0.947775956497703
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Gabrd ENSMUSG00000029054 0.423111511865783 0.634667267798675 0.0760107699773406 0.228032309932022 0.663543952203221 0.663543952203221
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Slc17a6 ENSMUSG00000030500 0.795756816312547 0.887473643997066 0.828388736158169 0.887473643997066 0.887473643997066 0.887473643997066
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Dnah2 ENSMUSG00000005237 0.586729703287127 0.741913289594388 0.573591465760119 0.741913289594388 0.741913289594388 0.741913289594388
Tomm40l ENSMUSG00000005674 0.0800934588362411 0.120140188254362 0.0226569544915107 0.067970863474532 0.445663114297173 0.445663114297173
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Trap1 ENSMUSG00000005981 0.806675895530585 0.883876855655631 0.773208027996425 0.883876855655631 0.883876855655631 0.883876855655631
Hap1 ENSMUSG00000006930 0.761137758535261 0.993701086721283 0.993701086721283 0.993701086721283 0.915140925930742 0.993701086721283
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Sqstm1 ENSMUSG00000015837 0.548220980587803 0.822331470881704 0.0231457389756086 0.0694372169268258 0.974803078046978 0.974803078046978
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Mapt ENSMUSG00000018411 0.921337224687564 0.921337224687564 0.649800002341703 0.921337224687564 0.862010536258072 0.921337224687564
Dnah11 ENSMUSG00000018581 0.886463462616174 0.936042136469891 0.936042136469891 0.936042136469891 0.684746557901969 0.936042136469891
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Nefh ENSMUSG00000020396 0.984092928979456 0.984092928979456 0.923172525800142 0.984092928979456 0.699369344852971 0.984092928979456
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Actr10 ENSMUSG00000021076 0.669849228095005 0.695941807023691 0.695941807023691 0.695941807023691 0.535250403728396 0.695941807023691
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Klc1 ENSMUSG00000021288 0.990553554869745 0.990553554869745 0.499421705389883 0.97901017485903 0.65267344990602 0.97901017485903
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Dnah12 ENSMUSG00000021879 0.561364858119941 0.924211505794983 0.924211505794983 0.924211505794983 0.775990540607666 0.924211505794983
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Nefm ENSMUSG00000022054 0.990305572230461 0.990305572230461 0.717163746116637 0.990305572230461 0.983899214115241 0.990305572230461
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Dnah5 ENSMUSG00000022262 0.814279518143365 0.814279518143365 0.663432885475693 0.814279518143365 0.734493843997311 0.814279518143365
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Dnal4 ENSMUSG00000022420 0.436381514240731 0.654572271361096 0.411168450969018 0.654572271361096 0.855941018476176 0.855941018476176
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Sncaip ENSMUSG00000024534 0.782299968721068 0.902557562018604 0.260890993758626 0.782672981275878 0.902557562018604 0.902557562018604
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Klc2 ENSMUSG00000024862 0.585801855606971 0.843554760199039 0.73719338477814 0.843554760199039 0.843554760199039 0.843554760199039
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Casp12 ENSMUSG00000025887 0.940147595967578 0.940147595967578 0.803507280553444 0.940147595967578 0.422156100213102 0.940147595967578
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Capn2 ENSMUSG00000026509 0.746187747633598 0.773247051273166 0.296497506886398 0.773247051273166 0.773247051273166 0.773247051273166
Kif5c ENSMUSG00000026764 0.524835301545644 0.824923056977493 0.824923056977493 0.824923056977493 0.684013828925298 0.824923056977493
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Trpc3 ENSMUSG00000027716 0.506935424866727 0.76040313730009 0.32296198461377 0.76040313730009 0.80667193803308 0.80667193803308
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Uchl1 ENSMUSG00000029223 0.731278668192084 0.859038855354209 0.282046553342865 0.846139660028595 0.859038855354209 0.859038855354209
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Gabarapl1 ENSMUSG00000030161 0.535140432761299 0.535140432761299 0.194167648861091 0.535140432761299 0.450381081843525 0.535140432761299
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Rab39b ENSMUSG00000031202 0.454911882994977 0.745813440993424 0.736970222891981 0.745813440993424 0.745813440993424 0.745813440993424
Gabarapl2 ENSMUSG00000031950 0.224363901485535 0.427080118991053 0.382427620187507 0.427080118991053 0.427080118991053 0.427080118991053
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Dnaic2 ENSMUSG00000034706 0.977726122535014 0.977726122535014 0.404413110382697 0.977726122535014 0.698635606561837 0.977726122535014
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Actr1b ENSMUSG00000037351 0.402192951106987 0.537847575175214 0.196852173499775 0.537847575175214 0.537847575175214 0.537847575175214
Dnah10 ENSMUSG00000038011 0.572160684738917 0.907893546588212 0.759404657401052 0.907893546588212 0.907893546588212 0.907893546588212
Gpr37 ENSMUSG00000039904 0.966888860531268 0.966888860531268 0.728518758974939 0.966888860531268 0.655532904753802 0.966888860531268
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Map3k10 ENSMUSG00000040390 0.797416568671383 0.797416568671383 0.143784741677682 0.431354225033045 0.415446133016764 0.623169199525147
Dnah7b ENSMUSG00000041144 0.808757853070344 0.981010349430688 0.981010349430688 0.981010349430688 0.637111145624469 0.981010349430688
Dnal1 ENSMUSG00000042523 0.514502229253744 0.927656976618437 0.912002083727086 0.927656976618437 0.927656976618437 0.927656976618437
Atxn2 ENSMUSG00000042605 0.4156684733082 0.946507314155645 0.908883211959565 0.946507314155645 0.946507314155645 0.946507314155645
Dnali1 ENSMUSG00000042707 0.689193443323099 0.689193443323099 0.495390027248225 0.689193443323099 0.543612640636431 0.689193443323099
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Dnah3 ENSMUSG00000052273 0.797068229861284 0.797068229861284 0.392242270539527 0.797068229861284 0.569573834382587 0.797068229861284
Dnah6 ENSMUSG00000052861 1 1 0.964894371960309 1 0.291499578932055 0.874498736796164
Vapb ENSMUSG00000054455 0.215474278799918 0.322964424363342 0.0957451269320177 0.287235380796053 0.322964424363342 0.322964424363342
Dnah9 ENSMUSG00000056752 0.871194167441475 0.871194167441475 0.82339206243693 0.871194167441475 0.785246811464158 0.871194167441475
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Dnaic1 ENSMUSG00000061322 0.921396412573084 0.921396412573084 0.731258265895337 0.921396412573084 0.868333573227398 0.921396412573084
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Uba1y ENSMUSG00000069053 0.741643912301594 0.958989154406724 0.958989154406724 0.958989154406724 0.787524234611823 0.958989154406724
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Sept5 ENSMUSG00000072214 0.743142056871386 0.862125857520565 0.635540077322335 0.862125857520565 0.862125857520565 0.862125857520565
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Kif5a ENSMUSG00000074657 0.968501666827124 0.968501666827124 0.758149741930825 0.968501666827124 0.646684223292294 0.968501666827124
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Prnp ENSMUSG00000079037 0.874534338960397 0.874534338960397 0.504457351146993 0.874534338960397 0.752129318305354 0.874534338960397
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037
Dnah7a ENSMUSG00000096141 0.356145717429228 0.534218576143842 0.271529423114921 0.534218576143842 0.890128601176218 0.890128601176218

Cholinergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Kcnq2 ENSMUSG00000016346 0.191950802282867 0.575852406848601 0.607230652075099 0.910845978112648 0.955922090241465 0.955922090241465
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Ache ENSMUSG00000023328 0.946471566718142 0.974793934304107 0.624361563049068 0.974793934304107 0.974793934304107 0.974793934304107
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Kcnq5 ENSMUSG00000028033 0.917881150154338 0.974704933577623 0.974704933577623 0.974704933577623 0.95254419357626 0.974704933577623
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Chrm4 ENSMUSG00000040495 0.713559919137436 0.713559919137436 0.653668107827576 0.713559919137436 0.639519564436859 0.713559919137436
Kcnj4 ENSMUSG00000044216 0.873689821994976 0.873689821994976 0.743411987257023 0.873689821994976 0.682604228641038 0.873689821994976
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Kcnq3 ENSMUSG00000056258 0.52812822993625 0.990176738721108 0.97033866766767 0.990176738721108 0.990176738721108 0.990176738721108
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Calcium signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Cacna1e ENSMUSG00000004110 0.685975098472301 0.829002490077136 0.628068597720699 0.829002490077136 0.829002490077136 0.829002490077136
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Camk1g ENSMUSG00000016179 0.968386914650231 0.968386914650231 0.324693205083142 0.914120795985816 0.609413863990544 0.914120795985816
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Htr7 ENSMUSG00000024798 0.71632417058308 0.865139469179896 0.865139469179896 0.865139469179896 0.7821207757961 0.865139469179896
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
P2rx3 ENSMUSG00000027071 0.457675632452868 0.457675632452868 0.427068943705184 0.457675632452868 0.361213091154555 0.457675632452868
Itpka ENSMUSG00000027296 0.374806260150845 0.968288666735599 0.968288666735599 0.968288666735599 0.814412248359697 0.968288666735599
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Tacr3 ENSMUSG00000028172 0.86353619522057 0.960980457908582 0.830458999836668 0.960980457908582 0.960980457908582 0.960980457908582
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Tacr1 ENSMUSG00000030043 0.874952532257405 0.990351663867859 0.990351663867859 0.990351663867859 0.910104110536735 0.990351663867859
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Grpr ENSMUSG00000031364 0.594100327338923 0.818349668482925 0.513345501338216 0.818349668482925 0.818349668482925 0.818349668482925
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Hrh1 ENSMUSG00000053004 0.870944697313483 0.870944697313483 0.578058362087012 0.870944697313483 0.64722556831022 0.870944697313483
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Ntrk2 ENSMUSG00000055254 0.834068612265552 0.90877116815938 0.886982277862293 0.90877116815938 0.90877116815938 0.90877116815938
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Ntrk3 ENSMUSG00000059146 0.899407856512363 0.899407856512363 0.695722258925379 0.899407856512363 0.657950245869533 0.899407856512363
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Retrograde endocannabinoid signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.844114356552196 0.947775956497703 0.699199242656938 0.947775956497703 0.947775956497703 0.947775956497703
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gabrd ENSMUSG00000029054 0.423111511865783 0.634667267798675 0.0760107699773406 0.228032309932022 0.663543952203221 0.663543952203221
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Slc17a6 ENSMUSG00000030500 0.795756816312547 0.887473643997066 0.828388736158169 0.887473643997066 0.887473643997066 0.887473643997066
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Mgll ENSMUSG00000033174 0.574971563922836 0.678474080357625 0.0332923773738217 0.099877132121465 0.678474080357625 0.678474080357625
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Dagla ENSMUSG00000035735 0.716365652254505 0.921367628058699 0.886972832447325 0.921367628058699 0.921367628058699 0.921367628058699
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Rims1 ENSMUSG00000041670 0.971061648165571 0.971061648165571 0.867585361206689 0.971061648165571 0.870806705447258 0.971061648165571
Cnr1 ENSMUSG00000044288 0.745786054078664 0.949484405913581 0.793882327064725 0.949484405913581 0.949484405913581 0.949484405913581
Napepld ENSMUSG00000044968 0.249656243561981 0.748968730685943 0.797514487737115 0.797514487737115 0.635661066304671 0.797514487737115
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Neuroactive ligand-receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.844114356552196 0.947775956497703 0.699199242656938 0.947775956497703 0.947775956497703 0.947775956497703
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Vipr2 ENSMUSG00000011171 0.81442795927062 0.81442795927062 0.274336900623371 0.670413060812143 0.446942040541429 0.670413060812143
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Vip ENSMUSG00000019772 0.334662694857406 0.798906412142223 0.532604274761482 0.798906412142223 0.980663464337666 0.980663464337666
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Nmbr ENSMUSG00000019865 0.592774912955548 0.944018380658151 0.754309607011397 0.944018380658151 0.944018380658151 0.944018380658151
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Ntsr2 ENSMUSG00000020591 1 1 0.958561123765929 1 0.933224198368138 1
Gh ENSMUSG00000020713 0.889000026853833 0.889000026853833 0.708759154724793 0.889000026853833 0.468274279272654 0.889000026853833
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Tshr ENSMUSG00000020963 0.749652680700576 0.917286863864632 0.00541113501137084 0.0162334050341125 0.917286863864632 0.917286863864632
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
C3 ENSMUSG00000024164 0.675614763347999 0.97166728513593 0.97166728513593 0.97166728513593 0.893257765188331 0.97166728513593
Grm8 ENSMUSG00000024211 0.581459279843197 0.863797416908078 0.863797416908078 0.863797416908078 0.746413291246183 0.863797416908078
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Grp ENSMUSG00000024517 0.722584098475009 0.990287032276337 0.990287032276337 0.990287032276337 0.906223610168785 0.990287032276337
Htr7 ENSMUSG00000024798 0.71632417058308 0.865139469179896 0.865139469179896 0.865139469179896 0.7821207757961 0.865139469179896
Tac2 ENSMUSG00000025400 0.783864107879587 0.783864107879587 0.362610864480765 0.708757538619127 0.472505025746085 0.708757538619127
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
P2rx3 ENSMUSG00000027071 0.457675632452868 0.457675632452868 0.427068943705184 0.457675632452868 0.361213091154555 0.457675632452868
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Oprl1 ENSMUSG00000027584 0.933329245678453 0.936720060465393 0.936720060465393 0.936720060465393 0.471739845590983 0.936720060465393
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Glrb ENSMUSG00000028020 0.262405896861402 0.629781498969239 0.610314670165233 0.629781498969239 0.629781498969239 0.629781498969239
Tacr3 ENSMUSG00000028172 0.86353619522057 0.960980457908582 0.830458999836668 0.960980457908582 0.960980457908582 0.960980457908582
Hcrtr1 ENSMUSG00000028778 0.776739267290508 0.776739267290508 0.483111972157679 0.776739267290508 0.534372493672934 0.776739267290508
Gabrd ENSMUSG00000029054 0.423111511865783 0.634667267798675 0.0760107699773406 0.228032309932022 0.663543952203221 0.663543952203221
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Tacr1 ENSMUSG00000030043 0.874952532257405 0.990351663867859 0.990351663867859 0.990351663867859 0.910104110536735 0.990351663867859
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Gipr ENSMUSG00000030406 0.818861357220811 0.910855665291448 0.910855665291448 0.910855665291448 0.840617980437171 0.910855665291448
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Calca ENSMUSG00000030669 0.588254249512147 0.83228400266544 0.5840247548685 0.83228400266544 0.83228400266544 0.83228400266544
Adm ENSMUSG00000030790 0.108342584744364 0.325027754233093 0.95279451230384 0.95279451230384 0.282037973830839 0.423056960746258
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Grpr ENSMUSG00000031364 0.594100327338923 0.818349668482925 0.513345501338216 0.818349668482925 0.818349668482925 0.818349668482925
Gpr83 ENSMUSG00000031932 0.758871649805916 0.758871649805916 0.360235075833073 0.758871649805916 0.700372029292482 0.758871649805916
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Hcrtr2 ENSMUSG00000032360 0.964816963971967 0.977590851896125 0.658466283082889 0.977590851896125 0.977590851896125 0.977590851896125
Cck ENSMUSG00000032532 0.848947018692305 1 0.653741884609598 1 1 1
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
P2ry2 ENSMUSG00000032860 0.843314101276018 0.843314101276018 0.76697890224979 0.843314101276018 0.70417554875783 0.843314101276018
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Rxfp1 ENSMUSG00000034009 0.867314449376788 0.867314449376788 0.504899795098141 0.867314449376788 0.741385117263809 0.867314449376788
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Sstr1 ENSMUSG00000035431 0.406238592066445 0.964057292265133 0.964057292265133 0.964057292265133 0.783863340301641 0.964057292265133
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Kiss1r ENSMUSG00000035773 0.692593027585027 0.692593027585027 0.66927584815228 0.692593027585027 0.566498128060593 0.692593027585027
Npy1r ENSMUSG00000036437 0.404299171034672 0.952738532723292 0.952738532723292 0.952738532723292 0.911889505521477 0.952738532723292
Apln ENSMUSG00000037010 0.75810612490527 0.75810612490527 0.661208628433793 0.75810612490527 0.675573817300198 0.75810612490527
Sstr4 ENSMUSG00000037014 0.219289047888821 0.558896666666789 0.55880869659876 0.558896666666789 0.558896666666789 0.558896666666789
Hrh3 ENSMUSG00000039059 0.561691926760614 0.924539440001392 0.924539440001392 0.924539440001392 0.750233152811516 0.924539440001392
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Chrm4 ENSMUSG00000040495 0.713559919137436 0.713559919137436 0.653668107827576 0.713559919137436 0.639519564436859 0.713559919137436
C3ar1 ENSMUSG00000040552 0.000211666510129739 0.000634999530389216 0.478720811527367 0.71808121729105 0.864363428489762 0.864363428489762
Grid1 ENSMUSG00000041078 0.914393248274356 0.914393248274356 0.725692863917251 0.914393248274356 0.713980419056347 0.914393248274356
Tspo ENSMUSG00000041736 0.171902826103889 0.376935193512112 0.251290129008075 0.376935193512112 0.713542607510652 0.713542607510652
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Cnr1 ENSMUSG00000044288 0.745786054078664 0.949484405913581 0.793882327064725 0.949484405913581 0.949484405913581 0.949484405913581
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
S1pr5 ENSMUSG00000045087 0.581310188081916 0.940038730735353 0.830636858120185 0.940038730735353 0.940038730735353 0.940038730735353
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Penk ENSMUSG00000045573 0.803570970818424 0.959069192685323 0.877609538741843 0.959069192685323 0.959069192685323 0.959069192685323
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Oprd1 ENSMUSG00000050511 0.843607928113184 0.887326964308433 0.802723620517678 0.887326964308433 0.887326964308433 0.887326964308433
Hrh1 ENSMUSG00000053004 0.870944697313483 0.870944697313483 0.578058362087012 0.870944697313483 0.64722556831022 0.870944697313483
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Grm7 ENSMUSG00000056755 0.858717824204382 0.977471956051544 0.625073995050131 0.977471956051544 0.977471956051544 0.977471956051544
Thra ENSMUSG00000058756 0.397736083742866 0.596604125614299 0.326891407506396 0.596604125614299 0.893254163676944 0.893254163676944
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Tac1 ENSMUSG00000061762 0.917404416369368 0.917404416369368 0.761517449025984 0.917404416369368 0.737667215472087 0.917404416369368
Grm4 ENSMUSG00000063239 0.758607855990508 0.89041686450784 0.89041686450784 0.89041686450784 0.819454188821776 0.89041686450784
Mas1 ENSMUSG00000068037 0.50528077101326 0.758878537445198 0.53871985258034 0.758878537445198 0.758878537445198 0.758878537445198

Long-term potentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Ppp1r1a ENSMUSG00000022490 0.666953074768298 0.959078277104945 0.728301782383287 0.959078277104945 0.959078277104945 0.959078277104945
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnn3 ENSMUSG00000000794 0.980981585411957 0.980981585411957 0.670545128861312 0.980981585411957 0.649193834819889 0.980981585411957
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Snap25 ENSMUSG00000027273 0.393197407602916 0.809550711908717 0.663727124914668 0.809550711908717 0.809550711908717 0.809550711908717
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Kcnu1 ENSMUSG00000031576 0.99369769862545 0.99369769862545 0.640956946124351 0.99369769862545 0.716341894312078 0.99369769862545
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cck ENSMUSG00000032532 0.848947018692305 1 0.653741884609598 1 1 1
Rims2 ENSMUSG00000037386 0.473695730086315 0.971342119526821 0.945981453982322 0.971342119526821 0.971342119526821 0.971342119526821
Kcnmb2 ENSMUSG00000037610 0.916247831827169 0.932300307938558 0.932300307938558 0.932300307938558 0.764799797741101 0.932300307938558
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Kcnn2 ENSMUSG00000054477 0.990553175175274 0.990553175175274 0.862134088048948 0.990553175175274 0.779274644686567 0.990553175175274
Kcnmb4 ENSMUSG00000054934 0.814060002714044 0.923634124055874 0.923634124055874 0.923634124055874 0.760665245028893 0.923634124055874
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Pclo ENSMUSG00000061601 0.611800743984937 0.933444242117645 0.933444242117645 0.933444242117645 0.655538670563311 0.933444242117645
Kcnma1 ENSMUSG00000063142 0.689942838580018 1 0.637840967371128 1 1 1
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Amphetamine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Th ENSMUSG00000000214 0.781258243079159 0.963513647581858 0.944303840944202 0.963513647581858 0.963513647581858 0.963513647581858
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Fosb ENSMUSG00000003545 0.224767765645433 0.624828878612626 0.442431005094042 0.624828878612626 0.624828878612626 0.624828878612626
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Arc ENSMUSG00000022602 0.880734558423853 0.914578100883835 0.524289975878998 0.914578100883835 0.914578100883835 0.914578100883835
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Synaptic vesicle cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Atp6v0a1 ENSMUSG00000019302 0.809740608147782 0.955939962928653 0.569613013889838 0.955939962928653 0.955939962928653 0.955939962928653
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Atp6v0c ENSMUSG00000024121 0.440973349549293 0.66146002432394 0.127040125857152 0.381120377571457 0.692901294735045 0.692901294735045
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
Cplx2 ENSMUSG00000025867 0.83430563562903 0.905754036220111 0.613280707051243 0.905754036220111 0.905754036220111 0.905754036220111
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Snap25 ENSMUSG00000027273 0.393197407602916 0.809550711908717 0.663727124914668 0.809550711908717 0.809550711908717 0.809550711908717
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Slc17a6 ENSMUSG00000030500 0.795756816312547 0.887473643997066 0.828388736158169 0.887473643997066 0.887473643997066 0.887473643997066
Stx1b ENSMUSG00000030806 0.993700757445583 0.993700757445583 0.319038980252528 0.802654952668384 0.535103301778923 0.802654952668384
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Unc13a ENSMUSG00000034799 0.962214355520355 0.987403979720273 0.257700597221577 0.773101791664731 0.987403979720273 0.987403979720273
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Atp6v0e2 ENSMUSG00000039347 0.375988428021386 0.563982642032079 0.307534606168789 0.563982642032079 0.746086632625595 0.746086632625595
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Rims1 ENSMUSG00000041670 0.971061648165571 0.971061648165571 0.867585361206689 0.971061648165571 0.870806705447258 0.971061648165571
Cltb ENSMUSG00000047547 0.990553491590513 0.990553491590513 0.38681165546803 0.990553491590513 0.791440238505949 0.990553491590513
Slc6a7 ENSMUSG00000052026 0.665798861742321 0.980966838363542 0.980966838363542 0.980966838363542 0.557176824775787 0.980966838363542
Unc13c ENSMUSG00000062151 0.859938638359961 0.970586553896047 0.970586553896047 0.970586553896047 0.92927625542795 0.970586553896047
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965

Oxytocin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Camk1g ENSMUSG00000016179 0.968386914650231 0.968386914650231 0.324693205083142 0.914120795985816 0.609413863990544 0.914120795985816
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Myl6b ENSMUSG00000039824 0.993701282995693 0.993701282995693 0.20384838527018 0.611545155810539 0.831203284451507 0.993701282995693
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Kcnj4 ENSMUSG00000044216 0.873689821994976 0.873689821994976 0.743411987257023 0.873689821994976 0.682604228641038 0.873689821994976
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Cacng8 ENSMUSG00000053395 0.661552013630507 0.987140983445108 0.987140983445108 0.987140983445108 0.631972341264415 0.987140983445108
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Aldosterone synthesis and secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkd1 ENSMUSG00000002688 0.666972482188133 0.666972482188133 0.219935308959217 0.659805926877651 0.517174035824954 0.666972482188133
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Camk1g ENSMUSG00000016179 0.968386914650231 0.968386914650231 0.324693205083142 0.914120795985816 0.609413863990544 0.914120795985816
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Nr4a2 ENSMUSG00000026826 0.233785975936429 0.701357927809288 0.709129574555477 0.876519250898046 0.876519250898046 0.876519250898046
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Cyp11a1 ENSMUSG00000032323 0.981031313469747 0.981031313469747 0.534651319112946 0.839856890233437 0.559904593488958 0.839856890233437
Dagla ENSMUSG00000035735 0.716365652254505 0.921367628058699 0.886972832447325 0.921367628058699 0.921367628058699 0.921367628058699
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Adrenergic signaling in cardiomyocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Ppp1r1a ENSMUSG00000022490 0.666953074768298 0.959078277104945 0.728301782383287 0.959078277104945 0.959078277104945 0.959078277104945
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Ppp2r2b ENSMUSG00000024500 0.949603809902928 0.949603809902928 0.779000669719215 0.949603809902928 0.716077271725534 0.949603809902928
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Tpm2 ENSMUSG00000028464 0.48901696268919 0.733525444033784 0.276643532403306 0.733525444033784 0.757962225810759 0.757962225810759
Ppp2r2c ENSMUSG00000029120 0.677925381424787 0.774758437583038 0.676212341554018 0.774758437583038 0.774758437583038 0.774758437583038
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Ppp2r2d ENSMUSG00000041769 0.737196580003877 0.740175941536255 0.411163215713724 0.740175941536255 0.740175941536255 0.740175941536255
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Cacng8 ENSMUSG00000053395 0.661552013630507 0.987140983445108 0.987140983445108 0.987140983445108 0.631972341264415 0.987140983445108
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Cocaine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Th ENSMUSG00000000214 0.781258243079159 0.963513647581858 0.944303840944202 0.963513647581858 0.963513647581858 0.963513647581858
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Fosb ENSMUSG00000003545 0.224767765645433 0.624828878612626 0.442431005094042 0.624828878612626 0.624828878612626 0.624828878612626
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Rgs9 ENSMUSG00000020599 0.892885470078516 0.892885470078516 0.842658173856563 0.892885470078516 0.787592383736084 0.892885470078516
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gpsm1 ENSMUSG00000026930 0.716461018413858 0.883894612012206 0.883894612012206 0.883894612012206 0.761180673630404 0.883894612012206
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798

Gap junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Tjp1 ENSMUSG00000030516 0.846641799814144 0.846641799814144 0.152738689196028 0.394456693036856 0.262971128691237 0.394456693036856
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Gja1 ENSMUSG00000050953 0.88701856986789 0.88701856986789 0.494408517230221 0.88701856986789 0.707647157078212 0.88701856986789
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Wnt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Wisp1 ENSMUSG00000005124 0.581539404609326 0.933740216225486 0.933740216225486 0.933740216225486 0.643451437324829 0.933740216225486
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Tle1 ENSMUSG00000008305 0.496911756913925 0.745367635370888 0.251309271945522 0.745367635370888 0.987405177840987 0.987405177840987
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Rspo3 ENSMUSG00000019880 0.704377225687392 0.955924594218963 0.955924594218963 0.955924594218963 0.64668573428511 0.955924594218963
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Fbxw11 ENSMUSG00000020271 0.825029488323122 0.825029488323122 0.246409415614068 0.739228246842205 0.767130154026292 0.825029488323122
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Sfrp4 ENSMUSG00000021319 0.76667452132186 0.76667452132186 0.663279056817344 0.76667452132186 0.539891939217786 0.76667452132186
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Ctnnd2 ENSMUSG00000022240 0.607554865475065 0.836573045218066 0.798711754278683 0.836573045218066 0.836573045218066 0.836573045218066
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Cby1 ENSMUSG00000022428 0.145983813172285 0.437951439516854 0.553222215065148 0.716217940767216 0.716217940767216 0.716217940767216
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Btrc ENSMUSG00000025217 0.599303880413449 0.658181099252517 0.187425393789642 0.562276181368927 0.658181099252517 0.658181099252517
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Vangl2 ENSMUSG00000026556 0.205120654318607 0.599533979729802 0.791415389189417 0.791415389189417 0.399689319819868 0.599533979729802
Sfrp2 ENSMUSG00000027996 0.883397632256836 0.883397632256836 0.839852498923077 0.883397632256836 0.643649598279821 0.883397632256836
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Ctnnbip1 ENSMUSG00000028988 0.734246974387656 0.91824507860527 0.289095599609497 0.867286798828492 0.91824507860527 0.91824507860527
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Prickle2 ENSMUSG00000030020 0.962212997081459 0.962212997081459 0.889982850866547 0.962212997081459 0.419770597792955 0.962212997081459
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Prickle3 ENSMUSG00000031145 0.550832639341945 0.826248959012918 0.831211751843443 0.831211751843443 0.535157145671516 0.826248959012918
Porcn ENSMUSG00000031169 0.865186181174899 0.865186181174899 0.572192687215947 0.858289030823921 0.276594223847887 0.829782671543661
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Daam1 ENSMUSG00000034574 0.905755554819822 0.905755554819822 0.382478128831209 0.810708178174994 0.54047211878333 0.810708178174994
Tle2 ENSMUSG00000034771 0.918272570941496 0.918272570941496 0.710588315612105 0.918272570941496 0.54834215471051 0.918272570941496
Prickle1 ENSMUSG00000036158 0.977959677761398 0.977959677761398 0.369553465019862 0.802794477155426 0.535196318103617 0.802794477155426
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Daam2 ENSMUSG00000040260 0.949652139997268 0.949652139997268 0.690092638326421 0.949652139997268 0.782322366393685 0.949652139997268
Cxxc4 ENSMUSG00000044365 0.908633874963891 0.908633874963891 0.864738917366639 0.908633874963891 0.867816839387876 0.908633874963891
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Gastric acid secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Slc9a4 ENSMUSG00000026065 0.816135961884783 0.816135961884783 0.499885151109367 0.816135961884783 0.766215783643848 0.816135961884783
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Kcnk10 ENSMUSG00000033854 0.66478227229457 0.943076748487154 0.943076748487154 0.943076748487154 0.75383616685965 0.943076748487154
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Slc26a7 ENSMUSG00000040569 0.898183482654752 0.898183482654752 0.834850210740357 0.898183482654752 0.702500444828441 0.898183482654752
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

GnRH secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnn3 ENSMUSG00000000794 0.980981585411957 0.980981585411957 0.670545128861312 0.980981585411957 0.649193834819889 0.980981585411957
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Hcn2 ENSMUSG00000020331 0.534981328000019 0.577729520726797 0.283774858742742 0.577729520726797 0.577729520726797 0.577729520726797
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Esr2 ENSMUSG00000021055 0.784976897267567 0.784976897267567 0.723231700240961 0.784976897267567 0.367625305269033 0.784976897267567
Hcn1 ENSMUSG00000021730 0.553676440072061 0.767040125638078 0.716868545276752 0.767040125638078 0.767040125638078 0.767040125638078
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Trpc4 ENSMUSG00000027748 0.767576880979932 0.888006864533746 0.888006864533746 0.888006864533746 0.815818518453809 0.888006864533746
Hcn3 ENSMUSG00000028051 0.771909102869138 0.867541689745964 0.627079137728601 0.867541689745964 0.867541689745964 0.867541689745964
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Kiss1r ENSMUSG00000035773 0.692593027585027 0.692593027585027 0.66927584815228 0.692593027585027 0.566498128060593 0.692593027585027
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gper1 ENSMUSG00000053647 0.340734658300866 0.5111019874513 0.305493224887898 0.5111019874513 0.580124431812303 0.580124431812303
Kcnn2 ENSMUSG00000054477 0.990553175175274 0.990553175175274 0.862134088048948 0.990553175175274 0.779274644686567 0.990553175175274
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Ras signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tiam1 ENSMUSG00000002489 0.990553275376873 0.990553275376873 0.794483074638216 0.990553275376873 0.743187703036167 0.990553275376873
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Pgf ENSMUSG00000004791 0.452863768911946 0.893240631057455 0.893240631057455 0.893240631057455 0.669785878407869 0.893240631057455
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Nf1 ENSMUSG00000020716 0.371683595114246 0.690103142447791 0.690103142447791 0.690103142447791 0.669823684327671 0.690103142447791
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Htr7 ENSMUSG00000024798 0.71632417058308 0.865139469179896 0.865139469179896 0.865139469179896 0.7821207757961 0.865139469179896
Rin1 ENSMUSG00000024883 0.937073421401496 0.937073421401496 0.874548958320838 0.937073421401496 0.602133058448573 0.937073421401496
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Abl2 ENSMUSG00000026596 0.632831580408566 0.915141605502986 0.915141605502986 0.915141605502986 0.887010537242205 0.915141605502986
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rasal1 ENSMUSG00000029602 0.549673540060143 0.949318299879298 0.72963301255346 0.949318299879298 0.949318299879298 0.949318299879298
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Pla2g3 ENSMUSG00000034579 0.936746172969225 0.936746172969225 0.526035563749265 0.936746172969225 0.754124209480741 0.936746172969225
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Pak7 ENSMUSG00000039913 0.594969319883574 0.948939766320461 0.881149414868131 0.948939766320461 0.948939766320461 0.948939766320461
Rapgef5 ENSMUSG00000041992 0.309574572968866 0.722980551638229 0.852840404804917 0.852840404804917 0.481987034425486 0.722980551638229
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Igf2 ENSMUSG00000048583 0.40217920293398 0.633683344836499 0.422455563224332 0.633683344836499 0.959077957494522 0.959077957494522
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Ntrk2 ENSMUSG00000055254 0.834068612265552 0.90877116815938 0.886982277862293 0.90877116815938 0.90877116815938 0.90877116815938
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Ksr2 ENSMUSG00000061578 0.794364244232228 0.821889995452819 0.821889995452819 0.821889995452819 0.728274844439839 0.821889995452819
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Syngap1 ENSMUSG00000067629 0.49917993882886 0.865184883031372 0.728298167799716 0.865184883031372 0.865184883031372 0.865184883031372
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Rasal2 ENSMUSG00000070565 0.375974690480065 0.837354234576499 0.837354234576499 0.837354234576499 0.690066143506778 0.837354234576499
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Pak6 ENSMUSG00000074923 0.320780926597679 0.898839487095189 0.599226324730126 0.898839487095189 0.96534841382286 0.96534841382286
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Melanogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

ErbB signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Abl2 ENSMUSG00000026596 0.632831580408566 0.915141605502986 0.915141605502986 0.915141605502986 0.887010537242205 0.915141605502986
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Map2k4 ENSMUSG00000033352 0.773245474965478 0.965374593178151 0.59400810630732 0.965374593178151 0.965374593178151 0.965374593178151
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Pak7 ENSMUSG00000039913 0.594969319883574 0.948939766320461 0.881149414868131 0.948939766320461 0.948939766320461 0.948939766320461
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Nrg2 ENSMUSG00000060275 0.516506828477907 0.987385309921187 0.987385309921187 0.987385309921187 0.745775162846842 0.987385309921187
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Nrg1 ENSMUSG00000062991 0.585044834185972 0.921183777349561 0.905524673048974 0.921183777349561 0.921183777349561 0.921183777349561
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Pak6 ENSMUSG00000074923 0.320780926597679 0.898839487095189 0.599226324730126 0.898839487095189 0.96534841382286 0.96534841382286
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Spinocerebellar ataxia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Atxn10 ENSMUSG00000016541 0.313363039166422 0.470044558749633 0.191451807526679 0.470044558749633 0.618859127308174 0.618859127308174
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Peo1 ENSMUSG00000025209 0.21838670372664 0.233663736443172 2.08655462149815e-05 6.25966386449444e-05 0.233663736443172 0.233663736443172
Fgf14 ENSMUSG00000025551 0.747022379030655 0.942672863796738 0.595449639332342 0.942672863796738 0.942672863796738 0.942672863796738
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Trpc3 ENSMUSG00000027716 0.506935424866727 0.76040313730009 0.32296198461377 0.76040313730009 0.80667193803308 0.80667193803308
Dab1 ENSMUSG00000028519 0.911931053123151 0.911931053123151 0.666573021804146 0.911931053123151 0.643795719176379 0.911931053123151
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Bean1 ENSMUSG00000031872 0.803428210775988 0.86485031245379 0.634226657898314 0.86485031245379 0.86485031245379 0.86485031245379
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Oma1 ENSMUSG00000035069 0.649822311558339 0.649822311558339 0.0222051001622298 0.0666153004866893 0.151563865886901 0.227345798830352
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Atxn2 ENSMUSG00000042605 0.4156684733082 0.946507314155645 0.908883211959565 0.946507314155645 0.946507314155645 0.946507314155645
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Kcnc3 ENSMUSG00000062785 0.264606770689471 0.548079307222063 0.365386204814709 0.548079307222063 0.79447941759174 0.79447941759174
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Rap1 signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sipa1l2 ENSMUSG00000001995 0.94022868702987 0.94022868702987 0.591280420286243 0.928292629549964 0.618861753033309 0.928292629549964
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tiam1 ENSMUSG00000002489 0.990553275376873 0.990553275376873 0.794483074638216 0.990553275376873 0.743187703036167 0.990553275376873
Prkd1 ENSMUSG00000002688 0.666972482188133 0.666972482188133 0.219935308959217 0.659805926877651 0.517174035824954 0.666972482188133
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Pgf ENSMUSG00000004791 0.452863768911946 0.893240631057455 0.893240631057455 0.893240631057455 0.669785878407869 0.893240631057455
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Pard6a ENSMUSG00000005699 0.540333259339338 0.540333259339338 0.17301166015541 0.519034980466231 0.48199026875276 0.540333259339338
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Pfn4 ENSMUSG00000020639 0.532293446478614 0.798440169717922 0.484398858733977 0.798440169717922 0.915070993815881 0.915070993815881
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Dock4 ENSMUSG00000035954 0.658331881967532 0.858992593219996 0.858992593219996 0.858992593219996 0.752153475021626 0.858992593219996
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Magi2 ENSMUSG00000040003 0.91820607599708 0.968501726648066 0.965332760650071 0.968501726648066 0.968501726648066 0.968501726648066
Rap1gap ENSMUSG00000041351 0.874516196622842 0.883872708327981 0.78529204277281 0.883872708327981 0.883872708327981 0.883872708327981
Rapgef5 ENSMUSG00000041992 0.309574572968866 0.722980551638229 0.852840404804917 0.852840404804917 0.481987034425486 0.722980551638229
Cnr1 ENSMUSG00000044288 0.745786054078664 0.949484405913581 0.793882327064725 0.949484405913581 0.949484405913581 0.949484405913581
Magi1 ENSMUSG00000045095 0.959084170291984 0.959084170291984 0.675620811660234 0.959084170291984 0.831231949597867 0.959084170291984
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Pard6g ENSMUSG00000056214 0.215469229904447 0.646407689713342 0.644138180114681 0.655513687932582 0.655513687932582 0.655513687932582
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Rapgef2 ENSMUSG00000062232 0.532650093135441 0.843568313157742 0.825066402286463 0.843568313157742 0.843568313157742 0.843568313157742
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Phospholipase D signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dgke ENSMUSG00000000276 0.438701356587272 0.93393028681949 0.93393028681949 0.93393028681949 0.641220236857371 0.93393028681949
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Ppap2a ENSMUSG00000021759 0.937088426646661 0.937088426646661 0.319118968965416 0.787332065610155 0.524888043740104 0.787332065610155
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Dgkg ENSMUSG00000022861 0.833650333926293 0.839891174827249 0.839891174827249 0.839891174827249 0.721688536261811 0.839891174827249
Grm8 ENSMUSG00000024211 0.581459279843197 0.863797416908078 0.863797416908078 0.863797416908078 0.746413291246183 0.863797416908078
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Agpat2 ENSMUSG00000026922 0.669795287704462 0.855937104795985 0.365300327242406 0.855937104795985 0.855937104795985 0.855937104795985
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ppap2b ENSMUSG00000028517 0.602184734910846 0.666965244141149 0.313311791875383 0.666965244141149 0.666965244141149 0.666965244141149
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Agpat5 ENSMUSG00000031467 0.530010954103118 0.795016431154677 0.499426790479466 0.795016431154677 0.797497893775486 0.797497893775486
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Dgkh ENSMUSG00000034731 0.388421388936085 0.869870998884137 0.579913999256091 0.869870998884137 0.971642477410861 0.971642477410861
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Dgkb ENSMUSG00000036095 0.530837257895833 0.958816829108309 0.958816829108309 0.958816829108309 0.780706242274577 0.958816829108309
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Dgki ENSMUSG00000038665 0.534194562344775 0.923422221300899 0.83838067754833 0.923422221300899 0.923422221300899 0.923422221300899
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Grm7 ENSMUSG00000056755 0.858717824204382 0.977471956051544 0.625073995050131 0.977471956051544 0.977471956051544 0.977471956051544
Grm4 ENSMUSG00000063239 0.758607855990508 0.89041686450784 0.89041686450784 0.89041686450784 0.819454188821776 0.89041686450784
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Regulation of lipolysis in adipocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Tshr ENSMUSG00000020963 0.749652680700576 0.917286863864632 0.00541113501137084 0.0162334050341125 0.917286863864632 0.917286863864632
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Pnpla2 ENSMUSG00000025509 0.725306786416421 0.940217394106596 0.194151870275104 0.582455610825313 0.940217394106596 0.940217394106596
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Aqp7 ENSMUSG00000028427 0.977629744194963 0.977629744194963 0.514492638704463 0.785363421843548 0.523575614562365 0.785363421843548
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Mgll ENSMUSG00000033174 0.574971563922836 0.678474080357625 0.0332923773738217 0.099877132121465 0.678474080357625 0.678474080357625
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Npy1r ENSMUSG00000036437 0.404299171034672 0.952738532723292 0.952738532723292 0.952738532723292 0.911889505521477 0.952738532723292
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Fabp4 ENSMUSG00000062515 0.788284548327433 0.874485635760368 0.874485635760368 0.874485635760368 0.658300267741111 0.874485635760368

Growth hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gh ENSMUSG00000020713 0.889000026853833 0.889000026853833 0.708759154724793 0.889000026853833 0.468274279272654 0.889000026853833
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Map2k4 ENSMUSG00000033352 0.773245474965478 0.965374593178151 0.59400810630732 0.965374593178151 0.965374593178151 0.965374593178151
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Sstr1 ENSMUSG00000035431 0.406238592066445 0.964057292265133 0.964057292265133 0.964057292265133 0.783863340301641 0.964057292265133
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Salivary secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Cst3 ENSMUSG00000027447 0.391140104045877 0.859037002005047 0.859037002005047 0.859037002005047 0.613300536496364 0.859037002005047
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Kcnma1 ENSMUSG00000063142 0.689942838580018 1 0.637840967371128 1 1 1
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Serotonergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Cyp2j9 ENSMUSG00000015224 0.877674944694298 0.877674944694298 0.436398759874103 0.877674944694298 0.669849332201509 0.877674944694298
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Alox8 ENSMUSG00000020891 0.891955303791901 0.891955303791901 0.72758433848346 0.891955303791901 0.48461289871988 0.891955303791901
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Htr7 ENSMUSG00000024798 0.71632417058308 0.865139469179896 0.865139469179896 0.865139469179896 0.7821207757961 0.865139469179896
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Htr3a ENSMUSG00000032269 0.831903629135955 0.891883337598266 0.891883337598266 0.891883337598266 0.866674769857056 0.891883337598266
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Alox12b ENSMUSG00000032807 0.875701887918677 0.993254428548925 0.993254428548925 0.993254428548925 0.98702627636772 0.993254428548925
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Cyp4x1 ENSMUSG00000047155 0.577634067496532 0.843550621189017 0.843550621189017 0.843550621189017 0.6726528958338 0.843550621189017
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Kcnn2 ENSMUSG00000054477 0.990553175175274 0.990553175175274 0.862134088048948 0.990553175175274 0.779274644686567 0.990553175175274
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Vascular smooth muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Myh10 ENSMUSG00000020900 0.825014485349748 0.825014485349748 0.0339671613529335 0.101901484058801 0.499299761244517 0.748949641866775
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Nppc ENSMUSG00000026241 0.609483026562215 0.93866457594603 0.785247476100659 0.93866457594603 0.93866457594603 0.93866457594603
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Calca ENSMUSG00000030669 0.588254249512147 0.83228400266544 0.5840247548685 0.83228400266544 0.83228400266544 0.83228400266544
Adm ENSMUSG00000030790 0.108342584744364 0.325027754233093 0.95279451230384 0.95279451230384 0.282037973830839 0.423056960746258
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Kcnu1 ENSMUSG00000031576 0.99369769862545 0.99369769862545 0.640956946124351 0.99369769862545 0.716341894312078 0.99369769862545
Ramp1 ENSMUSG00000034353 0.315244609202721 0.782329854444019 0.65548419813422 0.782329854444019 0.782329854444019 0.782329854444019
Pla2g3 ENSMUSG00000034579 0.936746172969225 0.936746172969225 0.526035563749265 0.936746172969225 0.754124209480741 0.936746172969225
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnmb2 ENSMUSG00000037610 0.916247831827169 0.932300307938558 0.932300307938558 0.932300307938558 0.764799797741101 0.932300307938558
Myl6b ENSMUSG00000039824 0.993701282995693 0.993701282995693 0.20384838527018 0.611545155810539 0.831203284451507 0.993701282995693
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Ramp3 ENSMUSG00000041046 0.698743119896013 0.825056637739825 0.183309696073174 0.549929088219521 0.825056637739825 0.825056637739825
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Kcnmb4 ENSMUSG00000054934 0.814060002714044 0.923634124055874 0.923634124055874 0.923634124055874 0.760665245028893 0.923634124055874
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kcnma1 ENSMUSG00000063142 0.689942838580018 1 0.637840967371128 1 1 1
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Cushing syndrome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Pde8b ENSMUSG00000021684 0.588529561107146 0.843506900088092 0.644018455010028 0.843506900088092 0.843506900088092 0.843506900088092
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Cdkn2c ENSMUSG00000028551 0.210858092532402 0.632574277597205 0.675523279883826 0.902549528004661 0.902549528004661 0.902549528004661
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Cyp11a1 ENSMUSG00000032323 0.981031313469747 0.981031313469747 0.534651319112946 0.839856890233437 0.559904593488958 0.839856890233437
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Kcna4 ENSMUSG00000042604 0.970307380221167 0.970307380221167 0.953991553652117 0.970307380221167 0.651894885265634 0.970307380221167
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Rasd1 ENSMUSG00000049892 0.367780254397946 0.733159755472243 0.733159755472243 0.733159755472243 0.558203411510132 0.733159755472243
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Pbx1 ENSMUSG00000052534 0.572292942272634 0.927670358750285 0.871453752008349 0.927670358750285 0.927670358750285 0.927670358750285
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Pde11a ENSMUSG00000075270 0.54212265120549 0.886803769999323 0.740010141364011 0.886803769999323 0.886803769999323 0.886803769999323
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Apelin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Hdac5 ENSMUSG00000008855 0.14698703697315 0.220480555459724 0.101458871721669 0.220480555459724 0.707628056979184 0.707628056979184
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Hdac4 ENSMUSG00000026313 0.883901009514773 0.984255611930778 0.704676249669995 0.984255611930778 0.984255611930778 0.984255611930778
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Gabarapl1 ENSMUSG00000030161 0.535140432761299 0.535140432761299 0.194167648861091 0.535140432761299 0.450381081843525 0.535140432761299
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Mef2a ENSMUSG00000030557 0.321019140520577 0.826436592338726 0.550957728225818 0.826436592338726 0.880780078245997 0.880780078245997
Plat ENSMUSG00000031538 0.815867258425008 0.815867258425008 0.395565746794447 0.599983046715482 0.399988697810322 0.599983046715482
Gabarapl2 ENSMUSG00000031950 0.224363901485535 0.427080118991053 0.382427620187507 0.427080118991053 0.427080118991053 0.427080118991053
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Apln ENSMUSG00000037010 0.75810612490527 0.75810612490527 0.661208628433793 0.75810612490527 0.675573817300198 0.75810612490527
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Egr1 ENSMUSG00000038418 0.212548573172272 0.637645719516816 0.908883404398007 0.908883404398007 0.773246460161634 0.908883404398007
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

cGMP-PKG signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Nppc ENSMUSG00000026241 0.609483026562215 0.93866457594603 0.785247476100659 0.93866457594603 0.93866457594603 0.93866457594603
Adra1d ENSMUSG00000027335 0.965258792378262 0.965258792378262 0.2218156156257 0.665446846877099 0.818553502625013 0.965258792378262
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Mef2a ENSMUSG00000030557 0.321019140520577 0.826436592338726 0.550957728225818 0.826436592338726 0.880780078245997 0.880780078245997
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Kcnu1 ENSMUSG00000031576 0.99369769862545 0.99369769862545 0.640956946124351 0.99369769862545 0.716341894312078 0.99369769862545
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnmb2 ENSMUSG00000037610 0.916247831827169 0.932300307938558 0.932300307938558 0.932300307938558 0.764799797741101 0.932300307938558
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Oprd1 ENSMUSG00000050511 0.843607928113184 0.887326964308433 0.802723620517678 0.887326964308433 0.887326964308433 0.887326964308433
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Kcnmb4 ENSMUSG00000054934 0.814060002714044 0.923634124055874 0.923634124055874 0.923634124055874 0.760665245028893 0.923634124055874
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gtf2i ENSMUSG00000060261 0.239978717678114 0.359968076517171 0.135226264789888 0.359968076517171 0.990552026320708 0.990552026320708
Kcnma1 ENSMUSG00000063142 0.689942838580018 1 0.637840967371128 1 1 1
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Cacna1e ENSMUSG00000004110 0.685975098472301 0.829002490077136 0.628068597720699 0.829002490077136 0.829002490077136 0.829002490077136
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Pgf ENSMUSG00000004791 0.452863768911946 0.893240631057455 0.893240631057455 0.893240631057455 0.669785878407869 0.893240631057455
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Mapkapk2 ENSMUSG00000016528 0.388749255153572 0.583123882730358 0.0933005842537308 0.279901752761192 0.779188546389634 0.779188546389634
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Mapt ENSMUSG00000018411 0.921337224687564 0.921337224687564 0.649800002341703 0.921337224687564 0.862010536258072 0.921337224687564
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Mknk2 ENSMUSG00000020190 0.943345734559456 0.943345734559456 0.303853057726799 0.911559173180397 0.74315958189619 0.943345734559456
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Nf1 ENSMUSG00000020716 0.371683595114246 0.690103142447791 0.690103142447791 0.690103142447791 0.669823684327671 0.690103142447791
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Ppm1a ENSMUSG00000021096 0.602159650179153 0.859013509531699 0.855935100104556 0.859013509531699 0.859013509531699 0.859013509531699
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Mapk8ip2 ENSMUSG00000022619 0.948575706158269 0.948575706158269 0.673671021072939 0.948575706158269 0.597041838173029 0.948575706158269
Map3k12 ENSMUSG00000023050 0.464879910055413 0.697319865083119 0.707654416004486 0.707654416004486 0.424816051313844 0.697319865083119
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Mapk8ip1 ENSMUSG00000027223 0.846652623757157 0.890129791342265 0.363332694193918 0.890129791342265 0.890129791342265 0.890129791342265
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Ptpn5 ENSMUSG00000030854 0.61651444934867 0.6834698016092 0.667901073333862 0.6834698016092 0.6834698016092 0.6834698016092
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Map2k4 ENSMUSG00000033352 0.773245474965478 0.965374593178151 0.59400810630732 0.965374593178151 0.965374593178151 0.965374593178151
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Dusp8 ENSMUSG00000037887 0.413364084032459 0.620046126048688 0.23839621310406 0.620046126048688 0.852819445432281 0.852819445432281
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Igf2 ENSMUSG00000048583 0.40217920293398 0.633683344836499 0.422455563224332 0.633683344836499 0.959077957494522 0.959077957494522
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Cacng8 ENSMUSG00000053395 0.661552013630507 0.987140983445108 0.987140983445108 0.987140983445108 0.631972341264415 0.987140983445108
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Ntrk2 ENSMUSG00000055254 0.834068612265552 0.90877116815938 0.886982277862293 0.90877116815938 0.90877116815938 0.90877116815938
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Hspa2 ENSMUSG00000059970 0.594008065071973 0.731292632575019 0.266394520925093 0.731292632575019 0.731292632575019 0.731292632575019
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Rapgef2 ENSMUSG00000062232 0.532650093135441 0.843568313157742 0.825066402286463 0.843568313157742 0.843568313157742 0.843568313157742
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Relaxin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Col4a6 ENSMUSG00000031273 0.384104158371494 0.766743553616261 0.96846938071278 0.96846938071278 0.511162369077507 0.766743553616261
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Map2k4 ENSMUSG00000033352 0.773245474965478 0.965374593178151 0.59400810630732 0.965374593178151 0.965374593178151 0.965374593178151
Rxfp1 ENSMUSG00000034009 0.867314449376788 0.867314449376788 0.504899795098141 0.867314449376788 0.741385117263809 0.867314449376788
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

GnRH signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Map2k4 ENSMUSG00000033352 0.773245474965478 0.965374593178151 0.59400810630732 0.965374593178151 0.965374593178151 0.965374593178151
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Egr1 ENSMUSG00000038418 0.212548573172272 0.637645719516816 0.908883404398007 0.908883404398007 0.773246460161634 0.908883404398007
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Long-term depression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Mannose type O-glycan biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Large ENSMUSG00000004383 0.896366978488347 0.896366978488347 0.450529588261087 0.896366978488347 0.893249744219163 0.896366978488347
Chst10 ENSMUSG00000026080 0.71210862932595 0.71210862932595 0.402039535114944 0.71210862932595 0.656258372953003 0.71210862932595
B4galt1 ENSMUSG00000028413 0.752176420041432 0.974813741144869 0.57497938457053 0.974813741144869 0.974813741144869 0.974813741144869
Fktn ENSMUSG00000028414 0.264667111152018 0.794001333456053 0.937088812154012 0.937088812154012 0.785353711912379 0.937088812154012
B4galt2 ENSMUSG00000028541 0.818935849510673 0.818935849510673 0.3933181046077 0.818935849510673 0.572250683911185 0.818935849510673
Pomt2 ENSMUSG00000034126 0.641299972263761 0.64409423689756 0.340767543062671 0.64409423689756 0.64409423689756 0.64409423689756
Pomk ENSMUSG00000037251 0.342765451664396 0.450493714276347 0.156155733895291 0.450493714276347 0.450493714276347 0.450493714276347
Ispd ENSMUSG00000043153 0.49436259942634 0.74154389913951 0.244769990257379 0.734309970772137 0.918274289428285 0.918274289428285
Mgat5b ENSMUSG00000043857 0.888996564304909 0.888996564304909 0.451543771865415 0.888996564304909 0.716213139094673 0.888996564304909
B3gat1 ENSMUSG00000045994 0.941590686501319 0.941590686501319 0.629538054037159 0.941590686501319 0.606171417556667 0.941590686501319
B3gnt1 ENSMUSG00000047379 0.294691733148561 0.442037599722842 0.0429821157516396 0.128946347254919 0.707547845600778 0.707547845600778
Pomgnt2 ENSMUSG00000066235 0.815868045926252 0.971667158666573 0.143792585463794 0.431377756391382 0.971667158666573 0.971667158666573

Renin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aqp1 ENSMUSG00000004655 0.583040083630381 0.583040083630381 0.0887911890511459 0.266373567153438 0.52227431095088 0.583040083630381
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Kcnma1 ENSMUSG00000063142 0.689942838580018 1 0.637840967371128 1 1 1

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Tpm2 ENSMUSG00000028464 0.48901696268919 0.733525444033784 0.276643532403306 0.733525444033784 0.757962225810759 0.757962225810759
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Dmd ENSMUSG00000045103 0.225948699264408 0.526297800726904 0.350865200484603 0.526297800726904 0.527417081123953 0.527417081123953
Cacng8 ENSMUSG00000053395 0.661552013630507 0.987140983445108 0.987140983445108 0.987140983445108 0.631972341264415 0.987140983445108
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pparg ENSMUSG00000000440 0.652636900013109 0.98110861041085 0.98110861041085 0.98110861041085 0.893254104438512 0.98110861041085
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Jag2 ENSMUSG00000002799 0.825018813526547 0.852805126170753 0.666931915072772 0.852805126170753 0.852805126170753 0.852805126170753
Gstm5 ENSMUSG00000004032 0.635450816723487 0.946506198877621 0.946506198877621 0.946506198877621 0.710358510493718 0.946506198877621
Pgf ENSMUSG00000004791 0.452863768911946 0.893240631057455 0.893240631057455 0.893240631057455 0.669785878407869 0.893240631057455
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Runx1t1 ENSMUSG00000006586 0.385630409164041 0.95584159348473 0.95584159348473 0.95584159348473 0.855408836100465 0.95584159348473
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Arnt2 ENSMUSG00000015709 0.776239958948181 0.94334630332242 0.94334630332242 0.94334630332242 0.840426352667481 0.94334630332242
Nfe2l2 ENSMUSG00000015839 0.359159026304938 0.591267901106213 0.422528930262444 0.591267901106213 0.591267901106213 0.591267901106213
Rarb ENSMUSG00000017491 0.14902327332072 0.447069819962161 0.314942841500812 0.472414262251218 0.893251817759664 0.893251817759664
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Hey2 ENSMUSG00000019789 0.452642840004662 0.962222098355059 0.962222098355059 0.962222098355059 0.930765818679163 0.962222098355059
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Ncoa1 ENSMUSG00000020647 0.846648700342619 0.893248582983702 0.893248582983702 0.893248582983702 0.88389669743103 0.893248582983702
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Esr2 ENSMUSG00000021055 0.784976897267567 0.784976897267567 0.723231700240961 0.784976897267567 0.367625305269033 0.784976897267567
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Dapk1 ENSMUSG00000021559 0.924541491486794 0.924541491486794 0.445794561039188 0.795086322912326 0.530057548608218 0.795086322912326
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Il15ra ENSMUSG00000023206 0.66695237533858 0.96222801613569 0.155061370749974 0.465184112249922 0.96222801613569 0.96222801613569
Cul2 ENSMUSG00000024231 0.690113612682011 0.690113612682011 0.15275780043895 0.45827340131685 0.553632011163728 0.690113612682011
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Gsto2 ENSMUSG00000025069 0.087347414727076 0.262042244181228 0.354591619785089 0.531887429677634 0.593081490494172 0.593081490494172
Il23a ENSMUSG00000025383 0.739088143963035 0.805608448517777 0.805608448517777 0.805608448517777 0.165597888999448 0.496793666998345
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ccna1 ENSMUSG00000027793 0.765131865615156 0.867803908356577 0.851936544535888 0.867803908356577 0.867803908356577 0.867803908356577
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Ptch2 ENSMUSG00000028681 0.855904303257423 0.868233071214486 0.868233071214486 0.868233071214486 0.574633027050076 0.868233071214486
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Col4a6 ENSMUSG00000031273 0.384104158371494 0.766743553616261 0.96846938071278 0.96846938071278 0.511162369077507 0.766743553616261
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Il15 ENSMUSG00000031712 0.87450252558752 0.98109370900104 0.98109370900104 0.98109370900104 0.582886891243668 0.98109370900104
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Dapk2 ENSMUSG00000032380 0.365407950847136 0.365407950847136 0.309583030475058 0.365407950847136 0.2124931703393 0.365407950847136
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Gstp2 ENSMUSG00000038155 0.328786286153638 0.493179429230457 0.3058097493524 0.493179429230457 0.915131070298161 0.915131070298161
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Plekhg5 ENSMUSG00000039713 0.779235921324691 0.779235921324691 0.749170734286215 0.779235921324691 0.519662892686707 0.779235921324691
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Hey1 ENSMUSG00000040289 0.779224795401036 0.977947939802305 0.406492465484631 0.977947939802305 0.977947939802305 0.977947939802305
Gstm2 ENSMUSG00000040562 0.553626824700737 0.846629027996803 0.67846858604625 0.846629027996803 0.846629027996803 0.846629027996803
Ar ENSMUSG00000046532 0.391159671868941 0.798934797899769 0.532623198599846 0.798934797899769 0.818931220190683 0.818931220190683
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Hes5 ENSMUSG00000048001 0.476298246261758 0.921171351852031 0.922983087031106 0.922983087031106 0.614114234568021 0.921171351852031
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929
Igf2 ENSMUSG00000048583 0.40217920293398 0.633683344836499 0.422455563224332 0.633683344836499 0.959077957494522 0.959077957494522
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Alk ENSMUSG00000055471 0.954386501496412 0.954386501496412 0.864230243306793 0.954386501496412 0.931376906022004 0.954386501496412
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Ctnna2 ENSMUSG00000063063 0.852580870048482 0.946358571486801 0.754645104338889 0.946358571486801 0.946358571486801 0.946358571486801
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Tceb1 ENSMUSG00000079658 0.577657760075684 0.60494974941873 0.60494974941873 0.60494974941873 0.47220069317445 0.60494974941873
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Estrogen signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Krt10 ENSMUSG00000019761 0.125705595661841 0.377116786985522 0.338557224863856 0.507835837295784 0.85333143674575 0.85333143674575
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Ncoa1 ENSMUSG00000020647 0.846648700342619 0.893248582983702 0.893248582983702 0.893248582983702 0.88389669743103 0.893248582983702
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Esr2 ENSMUSG00000021055 0.784976897267567 0.784976897267567 0.723231700240961 0.784976897267567 0.367625305269033 0.784976897267567
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Pgr ENSMUSG00000031870 0.547963212007977 0.618731259389758 0.618731259389758 0.618731259389758 0.567133180230395 0.618731259389758
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gper1 ENSMUSG00000053647 0.340734658300866 0.5111019874513 0.305493224887898 0.5111019874513 0.580124431812303 0.580124431812303
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Hspa2 ENSMUSG00000059970 0.594008065071973 0.731292632575019 0.266394520925093 0.731292632575019 0.731292632575019 0.731292632575019
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Cortisol synthesis and secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Pde8b ENSMUSG00000021684 0.588529561107146 0.843506900088092 0.644018455010028 0.843506900088092 0.843506900088092 0.843506900088092
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Cacna1h ENSMUSG00000024112 0.902542283762361 0.902542283762361 0.899420143747775 0.902542283762361 0.745993435315048 0.902542283762361
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Cyp11a1 ENSMUSG00000032323 0.981031313469747 0.981031313469747 0.534651319112946 0.839856890233437 0.559904593488958 0.839856890233437
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Kcna4 ENSMUSG00000042604 0.970307380221167 0.970307380221167 0.953991553652117 0.970307380221167 0.651894885265634 0.970307380221167
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Pbx1 ENSMUSG00000052534 0.572292942272634 0.927670358750285 0.871453752008349 0.927670358750285 0.927670358750285 0.927670358750285
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037

Hippo signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pard6a ENSMUSG00000005699 0.540333259339338 0.540333259339338 0.17301166015541 0.519034980466231 0.48199026875276 0.540333259339338
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Fbxw11 ENSMUSG00000020271 0.825029488323122 0.825029488323122 0.246409415614068 0.739228246842205 0.767130154026292 0.825029488323122
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Dlg5 ENSMUSG00000021782 0.959071531736581 0.959071531736581 0.716471746775062 0.959071531736581 0.806654158041075 0.959071531736581
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Snai2 ENSMUSG00000022676 0.585760165464656 0.878640248196984 0.940227987654184 0.940227987654184 0.221406735677816 0.664220207033449
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Ppp2r2b ENSMUSG00000024500 0.949603809902928 0.949603809902928 0.779000669719215 0.949603809902928 0.716077271725534 0.949603809902928
Btrc ENSMUSG00000025217 0.599303880413449 0.658181099252517 0.187425393789642 0.562276181368927 0.658181099252517 0.658181099252517
Limd1 ENSMUSG00000025239 0.332780716099088 0.499171074148633 0.266352692372264 0.499171074148633 0.927676157247166 0.927676157247166
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Trp73 ENSMUSG00000029026 0.615541303011644 0.990087455339935 0.990087455339935 0.990087455339935 0.841555839382332 0.990087455339935
Ppp2r2c ENSMUSG00000029120 0.677925381424787 0.774758437583038 0.676212341554018 0.774758437583038 0.774758437583038 0.774758437583038
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Amh ENSMUSG00000035262 0.781245551097063 0.781245551097063 0.282261166367888 0.781245551097063 0.739436278785459 0.781245551097063
Crb2 ENSMUSG00000035403 0.39088542862563 0.942537684600881 0.857485761437146 0.942537684600881 0.942537684600881 0.942537684600881
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Ppp2r2d ENSMUSG00000041769 0.737196580003877 0.740175941536255 0.411163215713724 0.740175941536255 0.740175941536255 0.740175941536255
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Ywhag ENSMUSG00000051391 0.561577446803949 0.842366170205924 0.0747261292216177 0.224178387664853 0.855885863447441 0.855885863447441
Bmpr1b ENSMUSG00000052430 0.393561355374609 0.833976643466496 0.833976643466496 0.833976643466496 0.809125982247177 0.833976643466496
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Pard6g ENSMUSG00000056214 0.215469229904447 0.646407689713342 0.644138180114681 0.655513687932582 0.655513687932582 0.655513687932582
Ctnna2 ENSMUSG00000063063 0.852580870048482 0.946358571486801 0.754645104338889 0.946358571486801 0.946358571486801 0.946358571486801
Crb1 ENSMUSG00000063681 0.87936237373235 0.917413950552626 0.768353194828429 0.917413950552626 0.917413950552626 0.917413950552626
Bmpr2 ENSMUSG00000067336 0.0957463246096653 0.287238973828996 0.399928403336969 0.599892605005454 0.987404529604506 0.987404529604506
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Alcoholism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Th ENSMUSG00000000214 0.781258243079159 0.963513647581858 0.944303840944202 0.963513647581858 0.963513647581858 0.963513647581858
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Fosb ENSMUSG00000003545 0.224767765645433 0.624828878612626 0.442431005094042 0.624828878612626 0.624828878612626 0.624828878612626
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Hdac5 ENSMUSG00000008855 0.14698703697315 0.220480555459724 0.101458871721669 0.220480555459724 0.707628056979184 0.707628056979184
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
H2afy2 ENSMUSG00000020086 0.658374390006999 0.95279264337918 0.779296495655047 0.95279264337918 0.95279264337918 0.95279264337918
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Slc29a2 ENSMUSG00000024891 0.507000988327154 0.693009715015452 0.658367097911268 0.693009715015452 0.693009715015452 0.693009715015452
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Hdac4 ENSMUSG00000026313 0.883901009514773 0.984255611930778 0.704676249669995 0.984255611930778 0.984255611930778 0.984255611930778
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Hdac6 ENSMUSG00000031161 0.399954411782688 0.704725705549976 0.604988890890964 0.704725705549976 0.704725705549976 0.704725705549976
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Hdac11 ENSMUSG00000034245 0.34684546046225 0.520268190693375 0.338709739409962 0.520268190693375 0.887013958523122 0.887013958523122
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Grin3b ENSMUSG00000035745 0.629578752849496 0.692730240304935 0.333920187382237 0.692730240304935 0.692730240304935 0.692730240304935
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Ntrk2 ENSMUSG00000055254 0.834068612265552 0.90877116815938 0.886982277862293 0.90877116815938 0.90877116815938 0.90877116815938
Hist3h2ba ENSMUSG00000056895 0.539777523854759 0.809666285782138 0.454630089662664 0.809666285782138 0.943293455378823 0.943293455378823
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Hist2h2aa2 ENSMUSG00000064220 0.0137218256303901 0.0411654768911703 0.496366960623321 0.496366960623321 0.0279623461725225 0.0419435192587837
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Hist4h4 ENSMUSG00000096010 0.638233217401902 0.957349826102853 0.993691763345742 0.993691763345742 0.635295276760744 0.957349826102853

Endocrine resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Jag2 ENSMUSG00000002799 0.825018813526547 0.852805126170753 0.666931915072772 0.852805126170753 0.852805126170753 0.852805126170753
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Bik ENSMUSG00000016758 0.234611139772008 0.703833419316025 0.677838781355548 0.952705505711688 0.952705505711688 0.952705505711688
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Esr2 ENSMUSG00000021055 0.784976897267567 0.784976897267567 0.723231700240961 0.784976897267567 0.367625305269033 0.784976897267567
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Cdkn2c ENSMUSG00000028551 0.210858092532402 0.632574277597205 0.675523279883826 0.902549528004661 0.902549528004661 0.902549528004661
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Gper1 ENSMUSG00000053647 0.340734658300866 0.5111019874513 0.305493224887898 0.5111019874513 0.580124431812303 0.580124431812303
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Mapt ENSMUSG00000018411 0.921337224687564 0.921337224687564 0.649800002341703 0.921337224687564 0.862010536258072 0.921337224687564
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Klc1 ENSMUSG00000021288 0.990553554869745 0.990553554869745 0.499421705389883 0.97901017485903 0.65267344990602 0.97901017485903
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Rtn3 ENSMUSG00000024758 0.583066701310634 0.672722108342328 0.672722108342328 0.672722108342328 0.616070574472783 0.672722108342328
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Klc2 ENSMUSG00000024862 0.585801855606971 0.843554760199039 0.73719338477814 0.843554760199039 0.843554760199039 0.843554760199039
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Casp12 ENSMUSG00000025887 0.940147595967578 0.940147595967578 0.803507280553444 0.940147595967578 0.422156100213102 0.940147595967578
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Capn2 ENSMUSG00000026509 0.746187747633598 0.773247051273166 0.296497506886398 0.773247051273166 0.773247051273166 0.773247051273166
Kif5c ENSMUSG00000026764 0.524835301545644 0.824923056977493 0.824923056977493 0.824923056977493 0.684013828925298 0.824923056977493
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Gpr83 ENSMUSG00000031932 0.758871649805916 0.758871649805916 0.360235075833073 0.758871649805916 0.700372029292482 0.758871649805916
Bace1 ENSMUSG00000032086 0.877670798063978 0.996851240146927 0.443377385148455 0.996851240146927 0.996851240146927 0.996851240146927
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Apbb1 ENSMUSG00000037032 0.330815392255874 0.508141310592384 0.338760873728256 0.508141310592384 0.930812058092768 0.930812058092768
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Lrp1 ENSMUSG00000040249 0.356652780548048 0.655396296030889 0.484009141223214 0.655396296030889 0.655396296030889 0.655396296030889
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Kif5a ENSMUSG00000074657 0.968501666827124 0.968501666827124 0.758149741930825 0.968501666827124 0.646684223292294 0.968501666827124
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Choline metabolism in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dgke ENSMUSG00000000276 0.438701356587272 0.93393028681949 0.93393028681949 0.93393028681949 0.641220236857371 0.93393028681949
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Pcyt1a ENSMUSG00000005615 0.993702051736308 0.993702051736308 0.0865587810070924 0.259676343021277 0.755175780065966 0.993702051736308
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Wasf1 ENSMUSG00000019831 0.987382907630171 0.987382907630171 0.692284847555358 0.987382907630171 0.466732870114758 0.987382907630171
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Ppap2a ENSMUSG00000021759 0.937088426646661 0.937088426646661 0.319118968965416 0.787332065610155 0.524888043740104 0.787332065610155
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Dgkg ENSMUSG00000022861 0.833650333926293 0.839891174827249 0.839891174827249 0.839891174827249 0.721688536261811 0.839891174827249
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Lypla1 ENSMUSG00000025903 0.474557263496955 0.711906776508762 0.474604517672508 0.711906776508762 0.9088641950551 0.9088641950551
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Slc44a5 ENSMUSG00000028360 0.44268732470733 0.870133623508318 0.864022214849736 0.870133623508318 0.870133623508318 0.870133623508318
Ppap2b ENSMUSG00000028517 0.602184734910846 0.666965244141149 0.313311791875383 0.666965244141149 0.666965244141149 0.666965244141149
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Wasf3 ENSMUSG00000029636 0.64123410769571 0.977957527082336 0.977957527082336 0.977957527082336 0.95593160210303 0.977957527082336
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Dgkh ENSMUSG00000034731 0.388421388936085 0.869870998884137 0.579913999256091 0.869870998884137 0.971642477410861 0.971642477410861
Pcyt1b ENSMUSG00000035246 0.618232357646927 0.618232357646927 0.601986745699676 0.618232357646927 0.520379553935938 0.618232357646927
Dgkb ENSMUSG00000036095 0.530837257895833 0.958816829108309 0.958816829108309 0.958816829108309 0.780706242274577 0.958816829108309
Dgki ENSMUSG00000038665 0.534194562344775 0.923422221300899 0.83838067754833 0.923422221300899 0.923422221300899 0.923422221300899
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Oocyte meiosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Fbxw11 ENSMUSG00000020271 0.825029488323122 0.825029488323122 0.246409415614068 0.739228246842205 0.767130154026292 0.825029488323122
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Btrc ENSMUSG00000025217 0.599303880413449 0.658181099252517 0.187425393789642 0.562276181368927 0.658181099252517 0.658181099252517
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Pgr ENSMUSG00000031870 0.547963212007977 0.618731259389758 0.618731259389758 0.618731259389758 0.567133180230395 0.618731259389758
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Anapc13 ENSMUSG00000035048 0.0464173373904588 0.085640115737412 0.057093410491608 0.085640115737412 0.47950255371891 0.47950255371891
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Cpeb2 ENSMUSG00000039782 0.427130296412659 0.905756005149073 0.877677234645987 0.905756005149073 0.905756005149073 0.905756005149073
Ar ENSMUSG00000046532 0.391159671868941 0.798934797899769 0.532623198599846 0.798934797899769 0.818931220190683 0.818931220190683
Ywhag ENSMUSG00000051391 0.561577446803949 0.842366170205924 0.0747261292216177 0.224178387664853 0.855885863447441 0.855885863447441
Spdya ENSMUSG00000052525 0.57396334472491 0.905545512963557 0.905545512963557 0.905545512963557 0.760456986538644 0.905545512963557
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Basal cell carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Ptch2 ENSMUSG00000028681 0.855904303257423 0.868233071214486 0.868233071214486 0.868233071214486 0.574633027050076 0.868233071214486
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Inflammatory mediator regulation of TRP channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Cyp2j9 ENSMUSG00000015224 0.877674944694298 0.877674944694298 0.436398759874103 0.877674944694298 0.669849332201509 0.877674944694298
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Asic2 ENSMUSG00000020704 0.510167169387105 0.933459849010855 0.933459849010855 0.933459849010855 0.886317826003193 0.933459849010855
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Asic1 ENSMUSG00000023017 0.777597274978441 0.936566325083334 0.936566325083334 0.936566325083334 0.883035401165312 0.936566325083334
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
P2ry2 ENSMUSG00000032860 0.843314101276018 0.843314101276018 0.76697890224979 0.843314101276018 0.70417554875783 0.843314101276018
Asic4 ENSMUSG00000033007 0.505425191865474 0.959284275176646 0.959284275176646 0.959284275176646 0.785101439020239 0.959284275176646
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Hrh1 ENSMUSG00000053004 0.870944697313483 0.870944697313483 0.578058362087012 0.870944697313483 0.64722556831022 0.870944697313483
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Neurotrophin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Matk ENSMUSG00000004933 0.393194068632188 0.698866333924087 0.698866333924087 0.698866333924087 0.613157696580203 0.698866333924087
Mapkapk2 ENSMUSG00000016528 0.388749255153572 0.583123882730358 0.0933005842537308 0.279901752761192 0.779188546389634 0.779188546389634
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Maged1 ENSMUSG00000025151 0.915133997137533 0.915133997137533 0.569595410977747 0.854393116466621 0.519729758625111 0.854393116466621
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Ntrk1 ENSMUSG00000028072 0.471087685287327 0.830406173269653 0.830406173269653 0.830406173269653 0.711721194720341 0.830406173269653
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Trp73 ENSMUSG00000029026 0.615541303011644 0.990087455339935 0.990087455339935 0.990087455339935 0.841555839382332 0.990087455339935
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Ngfrap1 ENSMUSG00000046432 0.946506652154109 0.946506652154109 0.613269482237527 0.946506652154109 0.849734644219946 0.946506652154109
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Ntrk2 ENSMUSG00000055254 0.834068612265552 0.90877116815938 0.886982277862293 0.90877116815938 0.90877116815938 0.90877116815938
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Ntrk3 ENSMUSG00000059146 0.899407856512363 0.899407856512363 0.695722258925379 0.899407856512363 0.657950245869533 0.899407856512363
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sort1 ENSMUSG00000068747 0.91201144822363 0.984256719255401 0.852842272841472 0.984256719255401 0.984256719255401 0.984256719255401
Arhgdig ENSMUSG00000073433 0.7641316519913 0.958987619354709 0.243424193642015 0.730272580926044 0.958987619354709 0.958987619354709

Breast cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Jag2 ENSMUSG00000002799 0.825018813526547 0.852805126170753 0.666931915072772 0.852805126170753 0.852805126170753 0.852805126170753
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Hey2 ENSMUSG00000019789 0.452642840004662 0.962222098355059 0.962222098355059 0.962222098355059 0.930765818679163 0.962222098355059
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Ncoa1 ENSMUSG00000020647 0.846648700342619 0.893248582983702 0.893248582983702 0.893248582983702 0.88389669743103 0.893248582983702
Esr2 ENSMUSG00000021055 0.784976897267567 0.784976897267567 0.723231700240961 0.784976897267567 0.367625305269033 0.784976897267567
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Pgr ENSMUSG00000031870 0.547963212007977 0.618731259389758 0.618731259389758 0.618731259389758 0.567133180230395 0.618731259389758
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Hey1 ENSMUSG00000040289 0.779224795401036 0.977947939802305 0.406492465484631 0.977947939802305 0.977947939802305 0.977947939802305
Hes5 ENSMUSG00000048001 0.476298246261758 0.921171351852031 0.922983087031106 0.922983087031106 0.614114234568021 0.921171351852031
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Huntington disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pparg ENSMUSG00000000440 0.652636900013109 0.98110861041085 0.98110861041085 0.98110861041085 0.893254104438512 0.98110861041085
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Dnah2 ENSMUSG00000005237 0.586729703287127 0.741913289594388 0.573591465760119 0.741913289594388 0.741913289594388 0.741913289594388
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Hap1 ENSMUSG00000006930 0.761137758535261 0.993701086721283 0.993701086721283 0.993701086721283 0.915140925930742 0.993701086721283
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Dnah11 ENSMUSG00000018581 0.886463462616174 0.936042136469891 0.936042136469891 0.936042136469891 0.684746557901969 0.936042136469891
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Actr10 ENSMUSG00000021076 0.669849228095005 0.695941807023691 0.695941807023691 0.695941807023691 0.535250403728396 0.695941807023691
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Klc1 ENSMUSG00000021288 0.990553554869745 0.990553554869745 0.499421705389883 0.97901017485903 0.65267344990602 0.97901017485903
Dnah12 ENSMUSG00000021879 0.561364858119941 0.924211505794983 0.924211505794983 0.924211505794983 0.775990540607666 0.924211505794983
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Dnah5 ENSMUSG00000022262 0.814279518143365 0.814279518143365 0.663432885475693 0.814279518143365 0.734493843997311 0.814279518143365
Dnal4 ENSMUSG00000022420 0.436381514240731 0.654572271361096 0.411168450969018 0.654572271361096 0.855941018476176 0.855941018476176
Klc2 ENSMUSG00000024862 0.585801855606971 0.843554760199039 0.73719338477814 0.843554760199039 0.843554760199039 0.843554760199039
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Kif5c ENSMUSG00000026764 0.524835301545644 0.824923056977493 0.824923056977493 0.824923056977493 0.684013828925298 0.824923056977493
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Dnaic2 ENSMUSG00000034706 0.977726122535014 0.977726122535014 0.404413110382697 0.977726122535014 0.698635606561837 0.977726122535014
Actr1b ENSMUSG00000037351 0.402192951106987 0.537847575175214 0.196852173499775 0.537847575175214 0.537847575175214 0.537847575175214
Tgm2 ENSMUSG00000037820 0.583072681167145 0.690099728725365 0.153890766589285 0.461672299767856 0.690099728725365 0.690099728725365
Dnah10 ENSMUSG00000038011 0.572160684738917 0.907893546588212 0.759404657401052 0.907893546588212 0.907893546588212 0.907893546588212
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Map3k10 ENSMUSG00000040390 0.797416568671383 0.797416568671383 0.143784741677682 0.431354225033045 0.415446133016764 0.623169199525147
Dnah7b ENSMUSG00000041144 0.808757853070344 0.981010349430688 0.981010349430688 0.981010349430688 0.637111145624469 0.981010349430688
Dnal1 ENSMUSG00000042523 0.514502229253744 0.927656976618437 0.912002083727086 0.927656976618437 0.927656976618437 0.927656976618437
Dnali1 ENSMUSG00000042707 0.689193443323099 0.689193443323099 0.495390027248225 0.689193443323099 0.543612640636431 0.689193443323099
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Cltb ENSMUSG00000047547 0.990553491590513 0.990553491590513 0.38681165546803 0.990553491590513 0.791440238505949 0.990553491590513
Bdnf ENSMUSG00000048482 0.84973945256386 0.962176221446086 0.911881045465043 0.962176221446086 0.962176221446086 0.962176221446086
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Dnah3 ENSMUSG00000052273 0.797068229861284 0.797068229861284 0.392242270539527 0.797068229861284 0.569573834382587 0.797068229861284
Dnah6 ENSMUSG00000052861 1 1 0.964894371960309 1 0.291499578932055 0.874498736796164
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Dnah9 ENSMUSG00000056752 0.871194167441475 0.871194167441475 0.82339206243693 0.871194167441475 0.785246811464158 0.871194167441475
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Dnaic1 ENSMUSG00000061322 0.921396412573084 0.921396412573084 0.731258265895337 0.921396412573084 0.868333573227398 0.921396412573084
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Kif5a ENSMUSG00000074657 0.968501666827124 0.968501666827124 0.758149741930825 0.968501666827124 0.646684223292294 0.968501666827124
Dnah7a ENSMUSG00000096141 0.356145717429228 0.534218576143842 0.271529423114921 0.534218576143842 0.890128601176218 0.890128601176218

Parathyroid hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Nr4a2 ENSMUSG00000026826 0.233785975936429 0.701357927809288 0.709129574555477 0.876519250898046 0.876519250898046 0.876519250898046
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Mmp24 ENSMUSG00000027612 0.578279168828671 0.903412597444634 0.903412597444634 0.903412597444634 0.820674570183018 0.903412597444634
Mmp16 ENSMUSG00000028226 0.867916001509585 0.867916001509585 0.793754560834957 0.867916001509585 0.489435229045102 0.867916001509585
Mmp17 ENSMUSG00000029436 0.905748495326935 0.977949982426564 0.309256283505843 0.927768850517529 0.977949982426564 0.977949982426564
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Mef2a ENSMUSG00000030557 0.321019140520577 0.826436592338726 0.550957728225818 0.826436592338726 0.880780078245997 0.880780078245997
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Egr1 ENSMUSG00000038418 0.212548573172272 0.637645719516816 0.908883404398007 0.908883404398007 0.773246460161634 0.908883404398007
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Pthlh ENSMUSG00000048776 0.383587759834659 0.852748962800843 0.852748962800843 0.852748962800843 0.681104328093666 0.852748962800843
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Proteoglycans in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tiam1 ENSMUSG00000002489 0.990553275376873 0.990553275376873 0.794483074638216 0.990553275376873 0.743187703036167 0.990553275376873
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Twist2 ENSMUSG00000007805 0.617331114458121 0.706589647372866 0.706589647372866 0.706589647372866 0.523348930918854 0.706589647372866
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Drosha ENSMUSG00000022191 0.797501478416565 0.797501478416565 0.30767863471482 0.797501478416565 0.599455307408484 0.797501478416565
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Hspg2 ENSMUSG00000028763 0.303834733670602 0.455752100505904 0.0721188565027327 0.216356569508198 0.871427977373747 0.871427977373747
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Ank2 ENSMUSG00000032826 0.370757566807118 0.955855146499532 0.865221067788243 0.955855146499532 0.955855146499532 0.955855146499532
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Igf2 ENSMUSG00000048583 0.40217920293398 0.633683344836499 0.422455563224332 0.633683344836499 0.959077957494522 0.959077957494522
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Ank3 ENSMUSG00000069601 0.624331301781384 0.987398959929537 0.96537007240181 0.987398959929537 0.987398959929537 0.987398959929537
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

mTOR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Nprl2 ENSMUSG00000010057 0.965373638939467 0.965373638939467 0.803620851596565 0.965373638939467 0.695946776569777 0.965373638939467
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Gatsl2 ENSMUSG00000015944 0.880786261640148 0.971665647226704 0.785361685716861 0.971665647226704 0.971665647226704 0.971665647226704
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Grb10 ENSMUSG00000020176 0.862131756215552 0.862131756215552 0.326849349555167 0.862131756215552 0.725321363060051 0.862131756215552
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Wdr59 ENSMUSG00000031959 0.464840748618559 0.464840748618559 0.195501278217567 0.464840748618559 0.404344794778811 0.464840748618559
Fnip1 ENSMUSG00000035992 0.740053694613787 0.955913729080483 0.373852868117584 0.955913729080483 0.955913729080483 0.955913729080483
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Rragb ENSMUSG00000041658 0.704717721347726 0.893248831823063 0.893248831823063 0.893248831823063 0.725332139450961 0.893248831823063
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Hedgehog signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Fbxw11 ENSMUSG00000020271 0.825029488323122 0.825029488323122 0.246409415614068 0.739228246842205 0.767130154026292 0.825029488323122
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Boc ENSMUSG00000022687 0.849735390372532 0.849735390372532 0.424794906992154 0.637192360488232 0.330824113689029 0.637192360488232
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Btrc ENSMUSG00000025217 0.599303880413449 0.658181099252517 0.187425393789642 0.562276181368927 0.658181099252517 0.658181099252517
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Ptch2 ENSMUSG00000028681 0.855904303257423 0.868233071214486 0.868233071214486 0.868233071214486 0.574633027050076 0.868233071214486
Iqce ENSMUSG00000036555 0.566941151362421 0.803616855657452 0.782308596791148 0.803616855657452 0.803616855657452 0.803616855657452
Gpr161 ENSMUSG00000040836 0.641351415541962 0.641351415541962 0.636094396515636 0.641351415541962 0.608594226374364 0.641351415541962
Megf8 ENSMUSG00000045039 0.434032081062991 0.651048121594486 0.206770218454699 0.620310655364097 0.746177345920419 0.746177345920419
BC030336 ENSMUSG00000046096 0.599324344689501 0.599324344689501 0.548298330295401 0.599324344689501 0.572150786112252 0.599324344689501
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929

Regulation of actin cytoskeleton

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tiam1 ENSMUSG00000002489 0.990553275376873 0.990553275376873 0.794483074638216 0.990553275376873 0.743187703036167 0.990553275376873
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Pip4k2b ENSMUSG00000018547 0.918263049106186 0.971666725496191 0.761164094951424 0.971666725496191 0.971666725496191 0.971666725496191
Wasf1 ENSMUSG00000019831 0.987382907630171 0.987382907630171 0.692284847555358 0.987382907630171 0.466732870114758 0.987382907630171
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Cyfip2 ENSMUSG00000020340 0.902622314461786 0.902622314461786 0.479506878958537 0.902622314461786 0.794478318196054 0.902622314461786
Pfn4 ENSMUSG00000020639 0.532293446478614 0.798440169717922 0.484398858733977 0.798440169717922 0.915070993815881 0.915070993815881
Myh10 ENSMUSG00000020900 0.825014485349748 0.825014485349748 0.0339671613529335 0.101901484058801 0.499299761244517 0.748949641866775
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Myl12a ENSMUSG00000024048 0.893235036387356 0.893235036387356 0.564169435197058 0.846254152795587 0.506984599890042 0.846254152795587
Fgd1 ENSMUSG00000025265 0.618850897072831 0.943366293933116 0.806686983694517 0.943366293933116 0.943366293933116 0.943366293933116
Baiap2 ENSMUSG00000025372 0.655520132193387 0.930809206966178 0.773241139949879 0.930809206966178 0.930809206966178 0.930809206966178
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Abi2 ENSMUSG00000026782 0.746185667393215 0.899496541272375 0.658367741350229 0.899496541272375 0.899496541272375 0.899496541272375
Nckap1 ENSMUSG00000027002 0.877676665557576 0.877676665557576 0.599491128400968 0.877676665557576 0.632861371260489 0.877676665557576
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Arhgef4 ENSMUSG00000037509 0.468843486192612 0.703265229288918 0.800201936126389 0.800201936126389 0.328109742653581 0.703265229288918
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Pak7 ENSMUSG00000039913 0.594969319883574 0.948939766320461 0.881149414868131 0.948939766320461 0.948939766320461 0.948939766320461
Chrm4 ENSMUSG00000040495 0.713559919137436 0.713559919137436 0.653668107827576 0.713559919137436 0.639519564436859 0.713559919137436
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Fgfr3 ENSMUSG00000054252 0.309567850128228 0.890798097518024 0.990551367834952 0.990551367834952 0.593865398345349 0.890798097518024
Actr3b ENSMUSG00000056367 0.818908267030821 0.981105442220549 0.779239141040676 0.981105442220549 0.981105442220549 0.981105442220549
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Pak6 ENSMUSG00000074923 0.320780926597679 0.898839487095189 0.599226324730126 0.898839487095189 0.96534841382286 0.96534841382286

Insulin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Mknk2 ENSMUSG00000020190 0.943345734559456 0.943345734559456 0.303853057726799 0.911559173180397 0.74315958189619 0.943345734559456
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Acaca ENSMUSG00000020532 0.965372286644278 0.965372286644278 0.406664215661721 0.965372286644278 0.678507277649498 0.965372286644278
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Exoc7 ENSMUSG00000020792 0.865240848199277 0.877677248195614 0.591264128545861 0.877677248195614 0.877677248195614 0.877677248195614
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Sorbs1 ENSMUSG00000025006 0.90881130665311 0.949616235985105 0.852831161038092 0.949616235985105 0.949616235985105 0.949616235985105
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Pygb ENSMUSG00000033059 0.710581801439672 0.710581801439672 0.638476533251363 0.710581801439672 0.585797624314828 0.710581801439672
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Hk1 ENSMUSG00000037012 0.779299856766711 0.88390422717468 0.311474580150504 0.88390422717468 0.88390422717468 0.88390422717468
Ppp1r3f ENSMUSG00000039556 0.821923605441528 0.905725137421764 0.905725137421764 0.905725137421764 0.566873478798613 0.905725137421764
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Ppp1r3d ENSMUSG00000049999 0.930803179911709 0.930803179911709 0.782326489656222 0.930803179911709 0.591191849418055 0.930803179911709
Flot1 ENSMUSG00000059714 0.4022016946755 0.603302542013251 0.229028103922559 0.603302542013251 0.773247937931798 0.773247937931798
Flot2 ENSMUSG00000061981 0.46733854475993 0.701007817139895 0.244801647402033 0.701007817139895 0.974813100222686 0.974813100222686
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Extl3 ENSMUSG00000021978 0.464912871025909 0.697369306538864 0.13213092146298 0.39639276438894 0.752162123659232 0.752162123659232
Extl2 ENSMUSG00000027963 0.641257184915065 0.81280191180177 0.81280191180177 0.81280191180177 0.427048143552246 0.81280191180177
Ndst3 ENSMUSG00000027977 0.660777196351522 0.857130114130428 0.857130114130428 0.857130114130428 0.636488911543187 0.857130114130428
Xylt1 ENSMUSG00000030657 0.672671607172038 0.959074126152435 0.701789082635642 0.959074126152435 0.959074126152435 0.959074126152435
Hs2st1 ENSMUSG00000040151 0.899501307549021 0.899501307549021 0.332799292083218 0.899501307549021 0.776273209817288 0.899501307549021
Hs3st5 ENSMUSG00000044499 0.853996311088547 0.853996311088547 0.74123195090548 0.853996311088547 0.686076751806097 0.853996311088547
Hs3st2 ENSMUSG00000046321 0.838947706921784 0.996776192162678 0.996776192162678 0.996776192162678 0.967653626333733 0.996776192162678
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
Hs6st2 ENSMUSG00000062184 0.85887458944601 0.962178028086868 0.962178028086868 0.962178028086868 0.896335063174007 0.962178028086868
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689

Glioma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Camk1g ENSMUSG00000016179 0.968386914650231 0.968386914650231 0.324693205083142 0.914120795985816 0.609413863990544 0.914120795985816
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Endocrine and other factor-regulated calcium reabsorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Cltb ENSMUSG00000047547 0.990553491590513 0.990553491590513 0.38681165546803 0.990553491590513 0.791440238505949 0.990553491590513
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Phosphatidylinositol signaling system

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dgke ENSMUSG00000000276 0.438701356587272 0.93393028681949 0.93393028681949 0.93393028681949 0.641220236857371 0.93393028681949
Ocrl ENSMUSG00000001173 0.809740045497336 0.990553639240077 0.616080272886195 0.990553639240077 0.990553639240077 0.990553639240077
Pip4k2b ENSMUSG00000018547 0.918263049106186 0.971666725496191 0.761164094951424 0.971666725496191 0.971666725496191 0.971666725496191
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Dgkg ENSMUSG00000022861 0.833650333926293 0.839891174827249 0.839891174827249 0.839891174827249 0.721688536261811 0.839891174827249
Synj1 ENSMUSG00000022973 0.30394904722831 0.785363299076561 0.785363299076561 0.785363299076561 0.672716804405151 0.785363299076561
Synj2 ENSMUSG00000023805 0.984255543374431 0.984255543374431 0.70765678360609 0.984255543374431 0.859029946149896 0.984255543374431
Inpp4a ENSMUSG00000026113 0.940226768683594 0.940226768683594 0.477034118929143 0.940226768683594 0.800567263104043 0.940226768683594
Itpka ENSMUSG00000027296 0.374806260150845 0.968288666735599 0.968288666735599 0.968288666735599 0.814412248359697 0.968288666735599
Tmem55a ENSMUSG00000028221 0.809698750003905 0.809698750003905 0.140438813861077 0.421316441583232 0.661149620883371 0.809698750003905
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Ppip5k1 ENSMUSG00000033526 0.990552238399787 0.990552238399787 0.346685496309738 0.590020932238689 0.393347288159126 0.590020932238689
Dgkh ENSMUSG00000034731 0.388421388936085 0.869870998884137 0.579913999256091 0.869870998884137 0.971642477410861 0.971642477410861
Dgkb ENSMUSG00000036095 0.530837257895833 0.958816829108309 0.958816829108309 0.958816829108309 0.780706242274577 0.958816829108309
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Dgki ENSMUSG00000038665 0.534194562344775 0.923422221300899 0.83838067754833 0.923422221300899 0.923422221300899 0.923422221300899
Mtmr7 ENSMUSG00000039431 0.511833909866822 0.949633177590117 0.871351016739036 0.949633177590117 0.949633177590117 0.949633177590117
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Inpp5f ENSMUSG00000042105 0.828154236731209 0.828154236731209 0.80363122700931 0.828154236731209 0.74319597708603 0.828154236731209
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Cds2 ENSMUSG00000058793 0.812802835028704 0.812802835028704 0.373861910185049 0.812802835028704 0.572291482333859 0.812802835028704
Impad1 ENSMUSG00000066324 0.170666208755629 0.511998626266888 0.459968814702882 0.689953222054322 0.773203961913385 0.773203961913385
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Circadian rhythm

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxw11 ENSMUSG00000020271 0.825029488323122 0.825029488323122 0.246409415614068 0.739228246842205 0.767130154026292 0.825029488323122
Per1 ENSMUSG00000020893 0.000541797521443416 0.00162539256433025 0.382394047682372 0.573591071523558 0.952787619873185 0.952787619873185
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Btrc ENSMUSG00000025217 0.599303880413449 0.658181099252517 0.187425393789642 0.562276181368927 0.658181099252517 0.658181099252517
Npas2 ENSMUSG00000026077 0.743179262128254 0.743179262128254 0.222950489365791 0.668851468097374 0.527472303344127 0.743179262128254
Per3 ENSMUSG00000028957 0.233611626275099 0.350417439412648 0.0282904234650245 0.0848712703950736 0.821967874241668 0.821967874241668
Bhlhe41 ENSMUSG00000030256 0.971641288576702 0.971641288576702 0.556013616128007 0.882753328058348 0.588502218705565 0.882753328058348
Rorb ENSMUSG00000036192 0.810813695014772 0.816148385225622 0.816148385225622 0.816148385225622 0.668248207655281 0.816148385225622
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Cry2 ENSMUSG00000068742 0.199697542965788 0.599092628897364 0.457616404535946 0.686424606803918 0.918262503341441 0.918262503341441

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Zfp40 ENSMUSG00000002617 0.80056885469374 0.80056885469374 0.334716260439429 0.80056885469374 0.550950781567853 0.80056885469374
Zfp184 ENSMUSG00000006720 0.949638212355394 0.949638212355394 0.402172249483506 0.949638212355394 0.837355417013485 0.949638212355394
Zfp334 ENSMUSG00000017667 0.921378916266842 0.921378916266842 0.18999199605851 0.569975988175529 0.67846176863927 0.921378916266842
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Zfp354b ENSMUSG00000020335 0.638460477494928 0.843544670786569 0.758164188469448 0.843544670786569 0.843544670786569 0.843544670786569
Zfp354a ENSMUSG00000020364 0.874564183703419 0.92453952597023 0.92453952597023 0.92453952597023 0.837387941833519 0.92453952597023
Zfp251 ENSMUSG00000022526 0.946510981556723 0.98110877067639 0.621642867920011 0.98110877067639 0.98110877067639 0.98110877067639
Zfp641 ENSMUSG00000022987 0.348874644419012 0.787306346229126 0.524870897486084 0.787306346229126 0.865243113372495 0.865243113372495
Zfp605 ENSMUSG00000023284 0.102245237805039 0.306735713415118 0.395557866440859 0.51705625785626 0.51705625785626 0.51705625785626
C3 ENSMUSG00000024164 0.675614763347999 0.97166728513593 0.97166728513593 0.97166728513593 0.893257765188331 0.97166728513593
H2-M5 ENSMUSG00000024459 0.617720677291955 0.850921236665363 0.810418613390646 0.850921236665363 0.850921236665363 0.850921236665363
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Zfp37 ENSMUSG00000028389 0.161519311776208 0.484557935328623 0.806536199163805 0.806536199163805 0.73392638657247 0.806536199163805
Calr4 ENSMUSG00000028558 0.724126465380001 0.968416808459755 0.389898146325399 0.968416808459755 0.968416808459755 0.968416808459755
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Zfp248 ENSMUSG00000030145 0.512057997558628 0.977958831344997 0.785340240945955 0.977958831344997 0.977958831344997 0.977958831344997
Zik1 ENSMUSG00000030393 0.921388239164613 0.921388239164613 0.629960874304772 0.921388239164613 0.855917420194615 0.921388239164613
Zfp939 ENSMUSG00000030424 0.203799818762536 0.611399456287607 0.661219773215538 0.661219773215538 0.57761832696456 0.661219773215538
Zfp583 ENSMUSG00000030443 0.469732939803514 0.90261642829085 0.90261642829085 0.90261642829085 0.613258732474315 0.90261642829085
Zfp719 ENSMUSG00000030469 0.373892778774146 0.558901921795302 0.291052031121696 0.558901921795302 0.558901921795302 0.558901921795302
Zfp108 ENSMUSG00000030486 0.734259255210159 0.993702276748919 0.558924334366877 0.993702276748919 0.993702276748919 0.993702276748919
Zfp300 ENSMUSG00000031079 0.399853577743306 0.46968508529538 0.342666331922834 0.46968508529538 0.46968508529538 0.46968508529538
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Pvrl1 ENSMUSG00000032012 0.949652252269996 0.962228884180112 0.6216493344849 0.962228884180112 0.962228884180112 0.962228884180112
D3Ertd254e ENSMUSG00000033883 0.658360413080695 0.831218881290594 0.38029324804892 0.831218881290594 0.831218881290594 0.831218881290594
Zfp551 ENSMUSG00000034071 0.952778848590231 0.952778848590231 0.82195265873154 0.952778848590231 0.222949398745696 0.668848196237088
Ccl12 ENSMUSG00000035352 0.849294173138853 0.87111409750574 0.81558405325349 0.87111409750574 0.87111409750574 0.87111409750574
Zfp57 ENSMUSG00000036036 0.752067206894428 0.776024186232713 0.776024186232713 0.776024186232713 0.225488054561573 0.67646416368472
Mavs ENSMUSG00000037523 0.755108683475413 0.755108683475413 0.0310166081762539 0.0930498245287617 0.322848318918091 0.484272478377137
Zfp60 ENSMUSG00000037640 0.800577095466653 0.803615201353212 0.291044676017573 0.803615201353212 0.803615201353212 0.803615201353212
Zfp189 ENSMUSG00000039634 0.0194570624365555 0.0583711873096666 0.326725029072033 0.49008754360805 0.852806898019894 0.852806898019894
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Zfp879 ENSMUSG00000044296 0.868346946418146 0.908875857871878 0.627212567599039 0.908875857871878 0.908875857871878 0.908875857871878
Zfp612 ENSMUSG00000044676 0.761186543879631 0.908855680702249 0.908855680702249 0.908855680702249 0.529904282341441 0.908855680702249
Zfp354c ENSMUSG00000044807 0.457267291763994 0.684293686951612 0.684293686951612 0.684293686951612 0.501710426785837 0.684293686951612
Zfp316 ENSMUSG00000046658 0.402209226486386 0.728322825724567 0.728322825724567 0.728322825724567 0.638495587314267 0.728322825724567
Bst2 ENSMUSG00000046718 0.411139393582395 0.616709090373592 0.188762000543322 0.566286001629967 0.822006189091291 0.822006189091291
Zfp286 ENSMUSG00000047342 0.908881095056223 0.937087950009592 0.764192572499009 0.937087950009592 0.937087950009592 0.937087950009592
Zfp30 ENSMUSG00000047473 0.613243578153834 0.797507983390203 0.395485236739194 0.797507983390203 0.797507983390203 0.797507983390203
Zfp235 ENSMUSG00000047603 0.524874280541459 0.99370234002937 0.99370234002937 0.99370234002937 0.722379722166774 0.99370234002937
Zfp454 ENSMUSG00000048728 0.818921741891611 0.883893633628847 0.883893633628847 0.883893633628847 0.837384378666867 0.883893633628847
Zfp940 ENSMUSG00000050855 0.852716028636561 0.877676936553048 0.752000193234701 0.877676936553048 0.877676936553048 0.877676936553048
Zfp11 ENSMUSG00000051034 0.996851239443869 0.996851239443869 0.690116172640701 0.996851239443869 0.321026026818925 0.963078080456775
Zfp46 ENSMUSG00000051351 0.330813062874329 0.846368433938347 0.887013231683579 0.887013231683579 0.564245622625565 0.846368433938347
Zfp786 ENSMUSG00000051499 0.887013331938143 0.887013331938143 0.287437173514663 0.86231152054399 0.69884934455422 0.887013331938143
Zfp112 ENSMUSG00000052675 0.43635430815136 0.654531462227041 0.322977056446409 0.654531462227041 0.974813356035214 0.974813356035214
Zfp14 ENSMUSG00000053985 0.761167250597751 0.843557605577892 0.843557605577892 0.843557605577892 0.334772303715186 0.843557605577892
Zfp667 ENSMUSG00000054893 0.974805945560049 0.974805945560049 0.800525519330721 0.974805945560049 0.588423495637298 0.974805945560049
Zfp647 ENSMUSG00000054967 0.713219092921785 0.713219092921785 0.594006869241443 0.713219092921785 0.428735174301394 0.713219092921785
Zfp811 ENSMUSG00000055202 0.728308515618265 0.981103237046439 0.981103237046439 0.981103237046439 0.716389131255775 0.981103237046439
Zfp93 ENSMUSG00000055305 0.519745910628397 0.974813569674869 0.734248859461654 0.974813569674869 0.974813569674869 0.974813569674869
Zfp458 ENSMUSG00000055480 0.311258694603777 0.477653044812138 0.318435363208092 0.477653044812138 0.646591167831349 0.646591167831349
A430033K04Rik ENSMUSG00000056014 0.871452528383977 0.871452528383977 0.545718497321052 0.871452528383977 0.828154935608575 0.871452528383977
C030039L03Rik ENSMUSG00000057093 0.452762974596301 0.849687995914635 0.849687995914635 0.849687995914635 0.610281842383254 0.849687995914635
Zfp941 ENSMUSG00000060314 0.739655155646137 0.797263861331123 0.36003600375944 0.797263861331123 0.797263861331123 0.797263861331123
Zfp128 ENSMUSG00000060397 0.666961187831516 0.666961187831516 0.54038114509229 0.666961187831516 0.484355887777365 0.666961187831516
Zfp13 ENSMUSG00000062012 0.415674161717803 0.779248943487875 0.779248943487875 0.779248943487875 0.695855123528563 0.779248943487875
Zfp27 ENSMUSG00000062040 0.695906335467678 0.952792822384394 0.196918467913332 0.590755403739997 0.952792822384394 0.952792822384394
Zfp938 ENSMUSG00000062931 0.806655470541471 0.806655470541471 0.350821056660619 0.613326464189976 0.408884309459984 0.613326464189976
Gm13154 ENSMUSG00000065999 0.893002997831508 0.893002997831508 0.723980415828458 0.893002997831508 0.171612640150604 0.514837920451811
Zfp772 ENSMUSG00000066838 0.859035210883878 0.859035210883878 0.800570402641693 0.859035210883878 0.837390699098223 0.859035210883878
Zfp563 ENSMUSG00000067424 0.955938493616196 0.955938493616196 0.348871567657477 0.955938493616196 0.896379359033264 0.955938493616196
Zfp763 ENSMUSG00000067430 0.984256960023638 0.984256960023638 0.384627657495763 0.984256960023638 0.693015216020098 0.984256960023638
Zfp114 ENSMUSG00000068962 0.521137826746759 0.5699055778011 0.5699055778011 0.5699055778011 0.54462835722599 0.5699055778011
Zfp9 ENSMUSG00000072623 0.222894862775941 0.668684588327822 0.865243545530726 0.865243545530726 0.604983565104113 0.865243545530726
Zfp791 ENSMUSG00000074194 0.336768052053714 0.802823508619679 0.93708668827094 0.93708668827094 0.535215672413119 0.802823508619679
Zfp382 ENSMUSG00000074220 0.412817807937233 0.748076216041766 0.761011362344762 0.761011362344762 0.498717477361177 0.748076216041766
Zfp568 ENSMUSG00000074221 0.596734045219791 0.658283062202233 0.175603521747074 0.526810565241223 0.658283062202233 0.658283062202233
Zfp109 ENSMUSG00000074283 0.369647595779159 0.693742715476194 0.462495143650796 0.693742715476194 0.937088622905834 0.937088622905834
Zfp558 ENSMUSG00000074500 0.666909946699411 0.812728851526245 0.369469592240741 0.812728851526245 0.812728851526245 0.812728851526245
Gm14326 ENSMUSG00000078862 0.583083461106364 0.764186464681844 0.338776292974492 0.764186464681844 0.764186464681844 0.764186464681844
Gm14322 ENSMUSG00000078864 0.672719663052633 0.672719663052633 0.302053397634814 0.45308009645222 0.294703693801531 0.45308009645222
Gm14308 ENSMUSG00000078880 0.479524326287649 0.658357803388123 0.41793396087732 0.658357803388123 0.658357803388123 0.658357803388123
Gm2026 ENSMUSG00000078886 0.952792201122276 0.952792201122276 0.194094560286555 0.582283680859666 0.610501567708355 0.915752351562533
Gm6710 ENSMUSG00000078887 0.522285010564344 0.840465229628056 0.840465229628056 0.840465229628056 0.791419849977058 0.840465229628056
Gm14391 ENSMUSG00000078903 0.646987765112177 0.646987765112177 0.344808924934923 0.646987765112177 0.641317485325638 0.646987765112177
Gm14393 ENSMUSG00000078905 0.232118032194768 0.557633282472029 0.740208448216558 0.740208448216558 0.371755521648019 0.557633282472029
Zfp111 ENSMUSG00000087598 0.39333897311727 0.871455985744119 0.871455985744119 0.871455985744119 0.661210438648188 0.871455985744119
Zfp964 ENSMUSG00000091764 0.354934172823564 0.514620423066432 0.489364681372825 0.514620423066432 0.514620423066432 0.514620423066432
Gm7221 ENSMUSG00000092335 0.806636796650367 0.806636796650367 0.167857156800457 0.503571470401372 0.596601858694022 0.806636796650367
Zfp853 ENSMUSG00000093910 0.895278343143764 0.984121731848934 0.984121731848934 0.984121731848934 0.57323645386569 0.984121731848934
Zfp799 ENSMUSG00000095253 0.890115561614533 0.890115561614533 0.486923772842346 0.890115561614533 0.621576157305985 0.890115561614533

Progesterone-mediated oocyte maturation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Rps6ka6 ENSMUSG00000025665 0.930781015791782 0.937048639256301 0.937048639256301 0.937048639256301 0.905734717415883 0.937048639256301
Ccna1 ENSMUSG00000027793 0.765131865615156 0.867803908356577 0.851936544535888 0.867803908356577 0.867803908356577 0.867803908356577
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Pgr ENSMUSG00000031870 0.547963212007977 0.618731259389758 0.618731259389758 0.618731259389758 0.567133180230395 0.618731259389758
Anapc13 ENSMUSG00000035048 0.0464173373904588 0.085640115737412 0.057093410491608 0.085640115737412 0.47950255371891 0.47950255371891
Cpeb2 ENSMUSG00000039782 0.427130296412659 0.905756005149073 0.877677234645987 0.905756005149073 0.905756005149073 0.905756005149073
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Spdya ENSMUSG00000052525 0.57396334472491 0.905545512963557 0.905545512963557 0.905545512963557 0.760456986538644 0.905545512963557
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

Longevity regulating pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pparg ENSMUSG00000000440 0.652636900013109 0.98110861041085 0.98110861041085 0.98110861041085 0.893254104438512 0.98110861041085
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Adipoq ENSMUSG00000022878 0.148614600880852 0.256798700474195 0.649894220930573 0.649894220930573 0.171199133649463 0.256798700474195
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Adipor1 ENSMUSG00000026457 0.788368670010579 0.977960570821812 0.0721368433489326 0.216410530046798 0.977960570821812 0.977960570821812
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Camk4 ENSMUSG00000038128 0.859579786550626 0.894622016887379 0.793787642998516 0.894622016887379 0.894622016887379 0.894622016887379
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037

TGF-beta signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chrd ENSMUSG00000006958 0.806676403427109 0.987404090828008 0.987404090828008 0.987404090828008 0.785344427507419 0.987404090828008
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Id4 ENSMUSG00000021379 0.921395091348974 0.965369952596476 0.776234314315522 0.965369952596476 0.965369952596476 0.965369952596476
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Acvr1c ENSMUSG00000026834 0.269501931358281 0.808505794074844 0.568916558682512 0.842211590545021 0.842211590545021 0.842211590545021
Acvr1 ENSMUSG00000026836 0.977953319872943 0.987401924400251 0.548293857703592 0.987401924400251 0.987401924400251 0.987401924400251
Smad9 ENSMUSG00000027796 0.731244353887559 0.731244353887559 0.698789715055393 0.731244353887559 0.658356766644369 0.731244353887559
Thsd4 ENSMUSG00000032289 0.725227531364508 0.77264905366802 0.757472256002231 0.77264905366802 0.77264905366802 0.77264905366802
Neo1 ENSMUSG00000032340 0.815843386285531 0.815843386285531 0.479539413144783 0.815843386285531 0.664079307565856 0.815843386285531
Zfyve9 ENSMUSG00000034557 0.707647624407332 0.871445612826723 0.871445612826723 0.871445612826723 0.716469837579448 0.871445612826723
Amh ENSMUSG00000035262 0.781245551097063 0.781245551097063 0.282261166367888 0.781245551097063 0.739436278785459 0.781245551097063
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Nodal ENSMUSG00000037171 0.273035511277797 0.81910653383339 0.984152284786098 0.984152284786098 0.569701416858276 0.854552125287414
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Inhba ENSMUSG00000041324 0.730884867216995 0.730884867216995 0.509263904086825 0.730884867216995 0.322105507001608 0.730884867216995
Rgmb ENSMUSG00000048027 0.822006423595827 0.8343126918131 0.486948912146334 0.8343126918131 0.8343126918131 0.8343126918131
Nog ENSMUSG00000048616 0.86814556845512 0.86814556845512 0.612444874974413 0.86814556845512 0.63797927913484 0.86814556845512
Grem2 ENSMUSG00000050069 0.837371466940467 0.905748683880004 0.905748683880004 0.905748683880004 0.457651279359498 0.905748683880004
Acvr2a ENSMUSG00000052155 0.585809647549715 0.990552578118598 0.990552578118598 0.990552578118598 0.719401188044231 0.990552578118598
Bmpr1b ENSMUSG00000052430 0.393561355374609 0.833976643466496 0.833976643466496 0.833976643466496 0.809125982247177 0.833976643466496
Acvr2b ENSMUSG00000061393 0.246400829740229 0.739202489220686 0.740211608714803 0.968520528710471 0.968520528710471 0.968520528710471
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Bmpr2 ENSMUSG00000067336 0.0957463246096653 0.287238973828996 0.399928403336969 0.599892605005454 0.987404529604506 0.987404529604506
Rgma ENSMUSG00000070509 0.908882462450851 0.908882462450851 0.874562391952601 0.908882462450851 0.494410400030678 0.908882462450851

Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Xylt1 ENSMUSG00000030657 0.672671607172038 0.959074126152435 0.701789082635642 0.959074126152435 0.959074126152435 0.959074126152435
Chpf ENSMUSG00000032997 0.564224804621702 0.6900920474379 0.208182709704908 0.624548129114723 0.6900920474379 0.6900920474379
Chst11 ENSMUSG00000034612 0.984256392355295 0.984256392355295 0.797508779874515 0.984256392355295 0.722386232610309 0.984256392355295
Csgalnact1 ENSMUSG00000036356 0.806651935197191 0.806651935197191 0.472105688923919 0.708158533385879 0.40216403146488 0.708158533385879
Ust ENSMUSG00000047712 0.604589912333844 0.906884868500765 0.981069060734272 0.981069060734272 0.563307748957533 0.906884868500765
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
Chsy3 ENSMUSG00000058152 0.436347634369614 0.654521451554421 0.772914190509357 0.772914190509357 0.36263116795407 0.654521451554421
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689

Taste transduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Asic2 ENSMUSG00000020704 0.510167169387105 0.933459849010855 0.933459849010855 0.933459849010855 0.886317826003193 0.933459849010855
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
P2rx3 ENSMUSG00000027071 0.457675632452868 0.457675632452868 0.427068943705184 0.457675632452868 0.361213091154555 0.457675632452868
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Htr3a ENSMUSG00000032269 0.831903629135955 0.891883337598266 0.891883337598266 0.891883337598266 0.866674769857056 0.891883337598266
Hcn4 ENSMUSG00000032338 0.443454103242053 0.952585035070339 0.933630870552189 0.952585035070339 0.952585035070339 0.952585035070339
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Scn3a ENSMUSG00000057182 0.549822880279604 0.742640594103942 0.686490207224732 0.742640594103942 0.742640594103942 0.742640594103942
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Grm4 ENSMUSG00000063239 0.758607855990508 0.89041686450784 0.89041686450784 0.89041686450784 0.819454188821776 0.89041686450784
Scn2a1 ENSMUSG00000075318 0.19651465329244 0.58954395987732 0.919475212271158 0.919475212271158 0.878320961398532 0.919475212271158

Purine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Pde7b ENSMUSG00000019990 0.937081114683675 0.937081114683675 0.641303214236346 0.937081114683675 0.666946639848943 0.937081114683675
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Guk1 ENSMUSG00000020444 0.249678499357078 0.420230621616773 0.420230621616773 0.420230621616773 0.367492409481286 0.420230621616773
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Nme2 ENSMUSG00000020857 0.669855994813251 0.921403988638114 0.921403988638114 0.921403988638114 0.749184974137771 0.921403988638114
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Pde8b ENSMUSG00000021684 0.588529561107146 0.843506900088092 0.644018455010028 0.843506900088092 0.843506900088092 0.843506900088092
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Pde10a ENSMUSG00000023868 0.41714785599035 0.764255216098399 0.962160233881058 0.962160233881058 0.509503477398933 0.764255216098399
Xdh ENSMUSG00000024066 0.902627463985909 0.902627463985909 0.785335235461666 0.902627463985909 0.627203907658005 0.902627463985909
Ak8 ENSMUSG00000026807 0.813444172366659 0.891343016647473 0.694600379904827 0.891343016647473 0.891343016647473 0.891343016647473
Gmps ENSMUSG00000027823 0.194155376690956 0.582466130072868 0.638480846934331 0.74020327370064 0.74020327370064 0.74020327370064
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Gucy1b3 ENSMUSG00000028005 0.719410735384948 0.828138670333824 0.828138670333824 0.828138670333824 0.431747109165653 0.828138670333824
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Hddc3 ENSMUSG00000030532 0.486736965092026 0.730105447638039 0.94648429667244 0.94648429667244 0.21694638988466 0.65083916965398
Prps1 ENSMUSG00000031432 0.340756509882091 0.535586717678083 0.357057811785388 0.535586717678083 0.710577571623197 0.710577571623197
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Nme6 ENSMUSG00000032478 0.79128337065202 0.79128337065202 0.64121482977858 0.79128337065202 0.532475173308075 0.79128337065202
Nt5m ENSMUSG00000032615 0.273233765325639 0.273233765325639 0.0138335691898452 0.0415007075695355 0.169318299401022 0.253977449101532
Ak5 ENSMUSG00000039058 0.843054778456653 0.971184401069045 0.971184401069045 0.971184401069045 0.913866230056953 0.971184401069045
Ak7 ENSMUSG00000041323 0.977601294481387 0.977601294481387 0.908512594084776 0.977601294481387 0.916978098266445 0.977601294481387
Entpd3 ENSMUSG00000041608 0.851012078196038 0.901514582218342 0.79797344458432 0.901514582218342 0.901514582218342 0.901514582218342
Gucy1a2 ENSMUSG00000041624 0.231093767028469 0.674423466000931 0.669397300771334 0.674423466000931 0.674423466000931 0.674423466000931
Gucy2g ENSMUSG00000055523 0.61337661636242 0.61337661636242 0.567254525611689 0.61337661636242 0.51174974689007 0.61337661636242
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Pde11a ENSMUSG00000075270 0.54212265120549 0.886803769999323 0.740010141364011 0.886803769999323 0.886803769999323 0.886803769999323
Taf9 ENSMUSG00000078941 0.14931621308758 0.44794863926274 0.874541218478575 0.874541218478575 0.494162899054242 0.741244348581362
Ak9 ENSMUSG00000091415 0.659885467391666 0.856623985027875 0.498791550082638 0.856623985027875 0.856623985027875 0.856623985027875

Amyotrophic lateral sclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ulk2 ENSMUSG00000004798 0.482006341491847 0.72300951223777 0.344810167697816 0.72300951223777 0.996851277056852 0.996851277056852
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Dnah2 ENSMUSG00000005237 0.586729703287127 0.741913289594388 0.573591465760119 0.741913289594388 0.741913289594388 0.741913289594388
Tomm40l ENSMUSG00000005674 0.0800934588362411 0.120140188254362 0.0226569544915107 0.067970863474532 0.445663114297173 0.445663114297173
Hap1 ENSMUSG00000006930 0.761137758535261 0.993701086721283 0.993701086721283 0.993701086721283 0.915140925930742 0.993701086721283
Ubqln4 ENSMUSG00000008604 0.933940652821986 0.933940652821986 0.157335566141133 0.472006698423398 0.644148913562697 0.933940652821986
Sqstm1 ENSMUSG00000015837 0.548220980587803 0.822331470881704 0.0231457389756086 0.0694372169268258 0.974803078046978 0.974803078046978
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Dnah11 ENSMUSG00000018581 0.886463462616174 0.936042136469891 0.936042136469891 0.936042136469891 0.684746557901969 0.936042136469891
Map2k3 ENSMUSG00000018932 0.419945256842708 0.629917885264061 0.0828187321791314 0.248456196537394 0.658242703068046 0.658242703068046
Nefh ENSMUSG00000020396 0.984092928979456 0.984092928979456 0.923172525800142 0.984092928979456 0.699369344852971 0.984092928979456
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Pfn4 ENSMUSG00000020639 0.532293446478614 0.798440169717922 0.484398858733977 0.798440169717922 0.915070993815881 0.915070993815881
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Actr10 ENSMUSG00000021076 0.669849228095005 0.695941807023691 0.695941807023691 0.695941807023691 0.535250403728396 0.695941807023691
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Klc1 ENSMUSG00000021288 0.990553554869745 0.990553554869745 0.499421705389883 0.97901017485903 0.65267344990602 0.97901017485903
Dnah12 ENSMUSG00000021879 0.561364858119941 0.924211505794983 0.924211505794983 0.924211505794983 0.775990540607666 0.924211505794983
Nefm ENSMUSG00000022054 0.990305572230461 0.990305572230461 0.717163746116637 0.990305572230461 0.983899214115241 0.990305572230461
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Dnah5 ENSMUSG00000022262 0.814279518143365 0.814279518143365 0.663432885475693 0.814279518143365 0.734493843997311 0.814279518143365
Dnal4 ENSMUSG00000022420 0.436381514240731 0.654572271361096 0.411168450969018 0.654572271361096 0.855941018476176 0.855941018476176
Klc2 ENSMUSG00000024862 0.585801855606971 0.843554760199039 0.73719338477814 0.843554760199039 0.843554760199039 0.843554760199039
Casp12 ENSMUSG00000025887 0.940147595967578 0.940147595967578 0.803507280553444 0.940147595967578 0.422156100213102 0.940147595967578
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Kif5c ENSMUSG00000026764 0.524835301545644 0.824923056977493 0.824923056977493 0.824923056977493 0.684013828925298 0.824923056977493
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Atg13 ENSMUSG00000027244 0.962219197458327 0.962219197458327 0.109154741811523 0.327464225434568 0.794480516969788 0.962219197458327
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Ulk1 ENSMUSG00000029512 0.791410427364992 0.996850783411042 0.269833821754191 0.809501465262573 0.996850783411042 0.996850783411042
Gabarapl1 ENSMUSG00000030161 0.535140432761299 0.535140432761299 0.194167648861091 0.535140432761299 0.450381081843525 0.535140432761299
Grin2b ENSMUSG00000030209 0.742168526387719 0.961823162937341 0.916743134182202 0.961823162937341 0.961823162937341 0.961823162937341
Hdac6 ENSMUSG00000031161 0.399954411782688 0.704725705549976 0.604988890890964 0.704725705549976 0.704725705549976 0.704725705549976
Rab39b ENSMUSG00000031202 0.454911882994977 0.745813440993424 0.736970222891981 0.745813440993424 0.745813440993424 0.745813440993424
Gabarapl2 ENSMUSG00000031950 0.224363901485535 0.427080118991053 0.382427620187507 0.427080118991053 0.427080118991053 0.427080118991053
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Gria2 ENSMUSG00000033981 0.764986804326694 0.764986804326694 0.606517559919082 0.764986804326694 0.58222318499185 0.764986804326694
Dnaic2 ENSMUSG00000034706 0.977726122535014 0.977726122535014 0.404413110382697 0.977726122535014 0.698635606561837 0.977726122535014
Matr3 ENSMUSG00000037236 0.591273083025001 0.791433776717529 0.436403738235471 0.791433776717529 0.791433776717529 0.791433776717529
Actr1b ENSMUSG00000037351 0.402192951106987 0.537847575175214 0.196852173499775 0.537847575175214 0.537847575175214 0.537847575175214
Dnah10 ENSMUSG00000038011 0.572160684738917 0.907893546588212 0.759404657401052 0.907893546588212 0.907893546588212 0.907893546588212
Dnah7b ENSMUSG00000041144 0.808757853070344 0.981010349430688 0.981010349430688 0.981010349430688 0.637111145624469 0.981010349430688
Dnal1 ENSMUSG00000042523 0.514502229253744 0.927656976618437 0.912002083727086 0.927656976618437 0.927656976618437 0.927656976618437
Atxn2 ENSMUSG00000042605 0.4156684733082 0.946507314155645 0.908883211959565 0.946507314155645 0.946507314155645 0.946507314155645
Dnali1 ENSMUSG00000042707 0.689193443323099 0.689193443323099 0.495390027248225 0.689193443323099 0.543612640636431 0.689193443323099
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Ubqln2 ENSMUSG00000050148 0.494345262359078 0.741517893538617 0.236746639942645 0.710239919827935 0.993700988225418 0.993700988225418
Dnah3 ENSMUSG00000052273 0.797068229861284 0.797068229861284 0.392242270539527 0.797068229861284 0.569573834382587 0.797068229861284
Dnah6 ENSMUSG00000052861 1 1 0.964894371960309 1 0.291499578932055 0.874498736796164
Vapb ENSMUSG00000054455 0.215474278799918 0.322964424363342 0.0957451269320177 0.287235380796053 0.322964424363342 0.322964424363342
Dnah9 ENSMUSG00000056752 0.871194167441475 0.871194167441475 0.82339206243693 0.871194167441475 0.785246811464158 0.871194167441475
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Nrg2 ENSMUSG00000060275 0.516506828477907 0.987385309921187 0.987385309921187 0.987385309921187 0.745775162846842 0.987385309921187
Dnaic1 ENSMUSG00000061322 0.921396412573084 0.921396412573084 0.731258265895337 0.921396412573084 0.868333573227398 0.921396412573084
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Nrg1 ENSMUSG00000062991 0.585044834185972 0.921183777349561 0.905524673048974 0.921183777349561 0.921183777349561 0.921183777349561
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Kif5a ENSMUSG00000074657 0.968501666827124 0.968501666827124 0.758149741930825 0.968501666827124 0.646684223292294 0.968501666827124
Dnah7a ENSMUSG00000096141 0.356145717429228 0.534218576143842 0.271529423114921 0.534218576143842 0.890128601176218 0.890128601176218

Type II diabetes mellitus

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1e ENSMUSG00000004110 0.685975098472301 0.829002490077136 0.628068597720699 0.829002490077136 0.829002490077136 0.829002490077136
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Cacna1g ENSMUSG00000020866 0.782302410284507 0.782302410284507 0.616060205033287 0.782302410284507 0.66696825130967 0.782302410284507
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Adipoq ENSMUSG00000022878 0.148614600880852 0.256798700474195 0.649894220930573 0.649894220930573 0.171199133649463 0.256798700474195
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Hk1 ENSMUSG00000037012 0.779299856766711 0.88390422717468 0.311474580150504 0.88390422717468 0.88390422717468 0.88390422717468
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

PPAR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pparg ENSMUSG00000000440 0.652636900013109 0.98110861041085 0.98110861041085 0.98110861041085 0.893254104438512 0.98110861041085
Nr1h3 ENSMUSG00000002108 0.322973261470103 0.484459892205155 0.211057292397863 0.484459892205155 0.803604995305309 0.803604995305309
Angptl4 ENSMUSG00000002289 0.517125585196305 0.758176120614944 0.338745074699263 0.758176120614944 0.758176120614944 0.758176120614944
Cd36 ENSMUSG00000002944 0.865229595152466 0.918271216079192 0.918271216079192 0.918271216079192 0.846635625757792 0.918271216079192
Cpt1c ENSMUSG00000007783 0.713529791924307 0.713529791924307 0.429415834101028 0.644123751151542 0.259622298057475 0.644123751151542
Pltp ENSMUSG00000017754 0.0455782963784195 0.0683674445676292 0.0332961581676282 0.0683674445676292 0.661229852263671 0.661229852263671
Fabp7 ENSMUSG00000019874 0.965372475975142 0.965372475975142 0.859034728048228 0.965372475975142 0.949652499267354 0.965372475975142
Acsl6 ENSMUSG00000020333 0.943317502402514 0.943317502402514 0.482004381480811 0.943317502402514 0.8900389651864 0.943317502402514
Adipoq ENSMUSG00000022878 0.148614600880852 0.256798700474195 0.649894220930573 0.649894220930573 0.171199133649463 0.256798700474195
Sorbs1 ENSMUSG00000025006 0.90881130665311 0.949616235985105 0.852831161038092 0.949616235985105 0.949616235985105 0.949616235985105
Scd3 ENSMUSG00000025202 0.701015503112666 0.904674646399319 0.80297851045526 0.904674646399319 0.904674646399319 0.904674646399319
Scd2 ENSMUSG00000025203 0.877660443198248 0.877660443198248 0.874553432046684 0.877660443198248 0.834298104391682 0.877660443198248
Cyp27a1 ENSMUSG00000026170 0.806661418796948 0.822004606161436 0.822004606161436 0.822004606161436 0.806671049149955 0.822004606161436
Fabp5 ENSMUSG00000027533 0.491561673213957 0.737342509820936 0.868274175018993 0.868274175018993 0.3057196493634 0.737342509820936
Aqp7 ENSMUSG00000028427 0.977629744194963 0.977629744194963 0.514492638704463 0.785363421843548 0.523575614562365 0.785363421843548
Plin2 ENSMUSG00000028494 0.831226121210814 0.921407592186509 0.921407592186509 0.921407592186509 0.616061585045038 0.921407592186509
Cpt2 ENSMUSG00000028607 0.282062092873429 0.423093139310144 0.144734720355009 0.423093139310144 0.496765004797308 0.496765004797308
Acsl4 ENSMUSG00000031278 0.203923659236271 0.611770977708812 0.831219920926164 0.831219920926164 0.825072014238738 0.831219920926164
Acsbg1 ENSMUSG00000032281 0.268822411355748 0.689636779517849 0.735704528940873 0.735704528940873 0.459757853011899 0.689636779517849
Acsl3 ENSMUSG00000032883 0.238393789874622 0.715181369623866 0.740167267297243 0.740167267297243 0.615974694230415 0.740167267297243
Dbil5 ENSMUSG00000038057 0.30676891408771 0.559645624733263 0.604477484897237 0.604477484897237 0.373097083155508 0.559645624733263
Fabp4 ENSMUSG00000062515 0.788284548327433 0.874485635760368 0.874485635760368 0.874485635760368 0.658300267741111 0.874485635760368

Vasopressin-regulated water reabsorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Aqp4 ENSMUSG00000024411 0.602220892440917 0.602220892440917 0.294684913700519 0.602220892440917 0.588533812029574 0.602220892440917
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Dync1i1 ENSMUSG00000029757 0.812594681821339 0.927644345002271 0.927644345002271 0.927644345002271 0.666543997730284 0.927644345002271
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Dync1li2 ENSMUSG00000035770 0.535252137809611 0.933945421899857 0.831224283473137 0.933945421899857 0.933945421899857 0.933945421899857
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Arhgdig ENSMUSG00000073433 0.7641316519913 0.958987619354709 0.243424193642015 0.730272580926044 0.958987619354709 0.958987619354709

Thyroid hormone synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a5 ENSMUSG00000000792 0.913938744873726 0.942670912529914 0.942670912529914 0.942670912529914 0.794551873687548 0.942670912529914
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Tshr ENSMUSG00000020963 0.749652680700576 0.917286863864632 0.00541113501137084 0.0162334050341125 0.917286863864632 0.917286863864632
Adcy2 ENSMUSG00000021536 0.72234695490509 0.915133591174676 0.915133591174676 0.915133591174676 0.481971499019833 0.915133591174676
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Human papillomavirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Tsc2 ENSMUSG00000002496 0.788390544150064 0.98110918186537 0.380303168670458 0.98110918186537 0.98110918186537 0.98110918186537
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Pard6a ENSMUSG00000005699 0.540333259339338 0.540333259339338 0.17301166015541 0.519034980466231 0.48199026875276 0.540333259339338
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Tnr ENSMUSG00000015829 0.649806818152786 0.989680283118503 0.816324898950381 0.989680283118503 0.989680283118503 0.989680283118503
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Atp6v0a1 ENSMUSG00000019302 0.809740608147782 0.955939962928653 0.569613013889838 0.955939962928653 0.955939962928653 0.955939962928653
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Hey2 ENSMUSG00000019789 0.452642840004662 0.962222098355059 0.962222098355059 0.962222098355059 0.930765818679163 0.962222098355059
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Atp6v0c ENSMUSG00000024121 0.440973349549293 0.66146002432394 0.127040125857152 0.381120377571457 0.692901294735045 0.692901294735045
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
H2-M5 ENSMUSG00000024459 0.617720677291955 0.850921236665363 0.810418613390646 0.850921236665363 0.850921236665363 0.850921236665363
Ppp2r2b ENSMUSG00000024500 0.949603809902928 0.949603809902928 0.779000669719215 0.949603809902928 0.716077271725534 0.949603809902928
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Fas ENSMUSG00000024778 0.59382580633426 0.773181705476869 0.413333181739435 0.773181705476869 0.773181705476869 0.773181705476869
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Tsc1 ENSMUSG00000026812 0.698868765312678 0.971667174475335 0.971667174475335 0.971667174475335 0.883903712367073 0.971667174475335
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Ccna1 ENSMUSG00000027793 0.765131865615156 0.867803908356577 0.851936544535888 0.867803908356577 0.867803908356577 0.867803908356577
Thbs3 ENSMUSG00000028047 0.788372131560243 0.788372131560243 0.666942932606772 0.788372131560243 0.269790263619584 0.788372131560243
Col9a2 ENSMUSG00000028626 0.717182266053983 0.85480012261282 0.85480012261282 0.85480012261282 0.577044549040291 0.85480012261282
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Rheb ENSMUSG00000028945 0.779178423285602 0.831066068968896 0.698582160519289 0.831066068968896 0.831066068968896 0.831066068968896
Ppp2r2c ENSMUSG00000029120 0.677925381424787 0.774758437583038 0.676212341554018 0.774758437583038 0.774758437583038 0.774758437583038
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Col4a6 ENSMUSG00000031273 0.384104158371494 0.766743553616261 0.96846938071278 0.96846938071278 0.511162369077507 0.766743553616261
Eif4ebp1 ENSMUSG00000031490 0.764131882161749 0.806628198913755 0.779244763192102 0.806628198913755 0.806628198913755 0.806628198913755
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Ptgs2 ENSMUSG00000032487 0.449480450520887 0.76063775771149 0.842102150748512 0.842102150748512 0.507091838474326 0.76063775771149
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Atp6v0e2 ENSMUSG00000039347 0.375988428021386 0.563982642032079 0.307534606168789 0.563982642032079 0.746086632625595 0.746086632625595
Hey1 ENSMUSG00000040289 0.779224795401036 0.977947939802305 0.406492465484631 0.977947939802305 0.977947939802305 0.977947939802305
Ppp2r2d ENSMUSG00000041769 0.737196580003877 0.740175941536255 0.411163215713724 0.740175941536255 0.740175941536255 0.740175941536255
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Tubg2 ENSMUSG00000045007 0.908862847108223 0.987404869905985 0.987404869905985 0.987404869905985 0.655424439216485 0.987404869905985
Magi1 ENSMUSG00000045095 0.959084170291984 0.959084170291984 0.675620811660234 0.959084170291984 0.831231949597867 0.959084170291984
Hes5 ENSMUSG00000048001 0.476298246261758 0.921171351852031 0.922983087031106 0.922983087031106 0.614114234568021 0.921171351852031
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Creb5 ENSMUSG00000053007 0.955922419866037 0.955922419866037 0.602056948323294 0.955922419866037 0.825030065283504 0.955922419866037
Pard6g ENSMUSG00000056214 0.215469229904447 0.646407689713342 0.644138180114681 0.655513687932582 0.655513687932582 0.655513687932582
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Hepatocellular carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Gstm5 ENSMUSG00000004032 0.635450816723487 0.946506198877621 0.946506198877621 0.946506198877621 0.710358510493718 0.946506198877621
Apc ENSMUSG00000005871 0.599334432713867 0.965363960743912 0.880786975046796 0.965363960743912 0.965363960743912 0.965363960743912
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Wnt2 ENSMUSG00000010797 0.469717337556208 0.752892663039721 0.865234573669197 0.865234573669197 0.501928442026481 0.752892663039721
Nfe2l2 ENSMUSG00000015839 0.359159026304938 0.591267901106213 0.422528930262444 0.591267901106213 0.591267901106213 0.591267901106213
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Apc2 ENSMUSG00000020135 0.588534853902307 0.907468266511259 0.604978844340839 0.907468266511259 0.993702061581115 0.993702061581115
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Wnt7b ENSMUSG00000022382 0.432147958863478 0.648221938295217 0.426547115179976 0.648221938295217 0.889168941520018 0.889168941520018
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Wnt10b ENSMUSG00000022996 0.590579170407548 0.968231548973722 0.968231548973722 0.968231548973722 0.955388332004287 0.968231548973722
Lrp5 ENSMUSG00000024913 0.291027585400572 0.436541378100859 0.0808196605003983 0.242458981501195 0.852840713441949 0.852840713441949
Gsto2 ENSMUSG00000025069 0.087347414727076 0.262042244181228 0.354591619785089 0.531887429677634 0.593081490494172 0.593081490494172
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Wnt10a ENSMUSG00000026167 0.480201032738949 0.961308139710011 0.830438420674558 0.961308139710011 0.961308139710011 0.961308139710011
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Wnt16 ENSMUSG00000029671 0.244829280903526 0.734487842710578 0.792275607447482 0.792275607447482 0.605184260156355 0.792275607447482
Actl6b ENSMUSG00000029712 0.318219734753927 0.835806307506973 0.835806307506973 0.835806307506973 0.70404724505234 0.835806307506973
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Wnt7a ENSMUSG00000030093 0.817758469978519 0.909128048237386 0.909128048237386 0.909128048237386 0.805621712916588 0.909128048237386
Dpf1 ENSMUSG00000030584 0.98424113548373 0.98424113548373 0.631978034139016 0.98424113548373 0.97161481020437 0.98424113548373
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Wnt4 ENSMUSG00000036856 0.396597302543124 0.739588108174594 0.67457209147048 0.739588108174594 0.739588108174594 0.739588108174594
Gstp2 ENSMUSG00000038155 0.328786286153638 0.493179429230457 0.3058097493524 0.493179429230457 0.915131070298161 0.915131070298161
Tgfb2 ENSMUSG00000039239 0.977959916413515 0.990546589692119 0.990546589692119 0.990546589692119 0.831106747884846 0.990546589692119
Gstm2 ENSMUSG00000040562 0.553626824700737 0.846629027996803 0.67846858604625 0.846629027996803 0.846629027996803 0.846629027996803
Igf2 ENSMUSG00000048583 0.40217920293398 0.633683344836499 0.422455563224332 0.633683344836499 0.959077957494522 0.959077957494522
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366
Fzd10 ENSMUSG00000081683 0.651099323900858 0.894487214467037 0.894487214467037 0.894487214467037 0.699880358317166 0.894487214467037

Collecting duct acid secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Slc12a7 ENSMUSG00000017756 0.585810066458965 0.785352682969664 0.324905585919778 0.785352682969664 0.785352682969664 0.785352682969664
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Atp6v0a1 ENSMUSG00000019302 0.809740608147782 0.955939962928653 0.569613013889838 0.955939962928653 0.955939962928653 0.955939962928653
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Atp6v0c ENSMUSG00000024121 0.440973349549293 0.66146002432394 0.127040125857152 0.381120377571457 0.692901294735045 0.692901294735045
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
Atp6v0e2 ENSMUSG00000039347 0.375988428021386 0.563982642032079 0.307534606168789 0.563982642032079 0.746086632625595 0.746086632625595

Cell adhesion molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh4 ENSMUSG00000000305 0.883898435194215 0.962222928866681 0.962222928866681 0.962222928866681 0.499291839744365 0.962222928866681
Cadm3 ENSMUSG00000005338 0.927671252776153 0.927671252776153 0.87456157244408 0.927671252776153 0.776261754900064 0.927671252776153
Cntnap1 ENSMUSG00000017167 0.977959193052309 0.977959193052309 0.585651334954867 0.878477002432301 0.290895202638539 0.872685607915618
Nrcam ENSMUSG00000020598 0.268171218134967 0.804513654404901 0.952086553151868 0.97751654860826 0.97751654860826 0.97751654860826
Ncam2 ENSMUSG00000022762 0.218719880260966 0.656159640782899 0.519639455823328 0.66159696433208 0.66159696433208 0.66159696433208
Nrxn1 ENSMUSG00000024109 0.279779262365715 0.839337787097145 0.852677270554343 0.852677270554343 0.834258443605675 0.852677270554343
Cdh2 ENSMUSG00000024304 0.899500180223969 0.899500180223969 0.548331065648196 0.899500180223969 0.695924443971456 0.899500180223969
H2-M5 ENSMUSG00000024459 0.617720677291955 0.850921236665363 0.810418613390646 0.850921236665363 0.850921236665363 0.850921236665363
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Nfasc ENSMUSG00000026442 0.698355335532337 0.698355335532337 0.646491985253954 0.698355335532337 0.660344021623246 0.698355335532337
Nlgn3 ENSMUSG00000031302 0.834261108009541 0.834261108009541 0.663687609645552 0.834261108009541 0.73149757680789 0.834261108009541
L1cam ENSMUSG00000031391 0.698816829578787 0.782281595099861 0.731289141683251 0.782281595099861 0.782281595099861 0.782281595099861
Pvrl1 ENSMUSG00000032012 0.949652252269996 0.962228884180112 0.6216493344849 0.962228884180112 0.962228884180112 0.962228884180112
Cadm1 ENSMUSG00000032076 0.908882979006135 0.908882979006135 0.737236270265165 0.908882979006135 0.770227550031902 0.908882979006135
Neo1 ENSMUSG00000032340 0.815843386285531 0.815843386285531 0.479539413144783 0.815843386285531 0.664079307565856 0.815843386285531
Ptprm ENSMUSG00000033278 0.974811781680654 0.974811781680654 0.424791745512727 0.974811781680654 0.871449198810541 0.974811781680654
Nrxn2 ENSMUSG00000033768 0.862104740999051 0.984252983296475 0.984252983296475 0.984252983296475 0.734163734122391 0.984252983296475
Cd99l2 ENSMUSG00000035776 0.831230854501142 0.990553895501099 0.37175943059837 0.990553895501099 0.990553895501099 0.990553895501099
Cd276 ENSMUSG00000035914 0.45734563535956 0.943330099511879 0.877675906760672 0.943330099511879 0.943330099511879 0.943330099511879
Mag ENSMUSG00000036634 0.434844107200354 0.652266160800532 0.317077958691326 0.652266160800532 0.735323530397301 0.735323530397301
Cldn11 ENSMUSG00000037625 0.752089915518546 0.840659648480462 0.840659648480462 0.840659648480462 0.295325050277662 0.840659648480462
Cntnap2 ENSMUSG00000039419 0.839381294522564 0.955597954104837 0.707834294301364 0.955597954104837 0.955597954104837 0.955597954104837
Ncam1 ENSMUSG00000039542 0.722258080043709 0.908787865951429 0.553227326662843 0.908787865951429 0.908787865951429 0.908787865951429
Negr1 ENSMUSG00000040037 0.607553003052472 0.943350663269467 0.846628148231004 0.943350663269467 0.943350663269467 0.943350663269467
Lrrc4b ENSMUSG00000047085 0.580727279922867 0.939134465864034 0.939134465864034 0.939134465864034 0.760107131568757 0.939134465864034
Lrrc4 ENSMUSG00000049939 0.958742342237885 0.958742342237885 0.722693425151927 0.958742342237885 0.799954758249415 0.958742342237885
Lrrc4c ENSMUSG00000050587 0.663875578660822 0.874428669298983 0.821948238070675 0.874428669298983 0.874428669298983 0.874428669298983
Nlgn2 ENSMUSG00000051790 0.550986134941578 0.58308068198293 0.58308068198293 0.58308068198293 0.537847802454335 0.58308068198293
Cntn2 ENSMUSG00000053024 0.946920054315675 0.946920054315675 0.718580352683058 0.946920054315675 0.560606666115818 0.946920054315675
Cntn1 ENSMUSG00000055022 0.752146807187856 0.990542717718585 0.990542717718585 0.990542717718585 0.452332478335854 0.990542717718585
Ntng1 ENSMUSG00000059857 0.926534171334259 0.926534171334259 0.910073513352151 0.926534171334259 0.850476861484157 0.926534171334259
Nlgn1 ENSMUSG00000063887 0.474099503319141 0.848325369786747 0.772171931442803 0.848325369786747 0.848325369786747 0.848325369786747
Nrxn3 ENSMUSG00000066392 0.610968260752645 0.610968260752645 0.255408619944771 0.610968260752645 0.478572718844866 0.610968260752645
Cldn9 ENSMUSG00000066720 0.732417204356167 0.841614550327178 0.182898107603698 0.548694322811095 0.841614550327178 0.841614550327178

Arrhythmogenic right ventricular cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Cdh2 ENSMUSG00000024304 0.899500180223969 0.899500180223969 0.548331065648196 0.899500180223969 0.695924443971456 0.899500180223969
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Cacna1f ENSMUSG00000031142 0.664357873530962 0.787066279458481 0.787066279458481 0.787066279458481 0.704507700834386 0.787066279458481
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Dmd ENSMUSG00000045103 0.225948699264408 0.526297800726904 0.350865200484603 0.526297800726904 0.527417081123953 0.527417081123953
Gja1 ENSMUSG00000050953 0.88701856986789 0.88701856986789 0.494408517230221 0.88701856986789 0.707647157078212 0.88701856986789
Cacng8 ENSMUSG00000053395 0.661552013630507 0.987140983445108 0.987140983445108 0.987140983445108 0.631972341264415 0.987140983445108
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Ctnna2 ENSMUSG00000063063 0.852580870048482 0.946358571486801 0.754645104338889 0.946358571486801 0.946358571486801 0.946358571486801
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Focal adhesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Pgf ENSMUSG00000004791 0.452863768911946 0.893240631057455 0.893240631057455 0.893240631057455 0.669785878407869 0.893240631057455
Elk1 ENSMUSG00000009406 0.737183713562155 0.840374648554062 0.840374648554062 0.840374648554062 0.590976776823719 0.840374648554062
Tnr ENSMUSG00000015829 0.649806818152786 0.989680283118503 0.816324898950381 0.989680283118503 0.989680283118503 0.989680283118503
Rac3 ENSMUSG00000018012 0.740132281715589 0.740132281715589 0.276360057901422 0.740132281715589 0.629900134177704 0.740132281715589
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Flt4 ENSMUSG00000020357 0.899466074666633 0.899466074666633 0.176883598607824 0.530650795823472 0.641277909615338 0.899466074666633
Mapk9 ENSMUSG00000020366 0.871455288603417 0.927677413404358 0.566944965404123 0.927677413404358 0.927677413404358 0.927677413404358
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Myl12a ENSMUSG00000024048 0.893235036387356 0.893235036387356 0.564169435197058 0.846254152795587 0.506984599890042 0.846254152795587
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Pdgfa ENSMUSG00000025856 0.190077772451637 0.355204096123431 0.236802730748954 0.355204096123431 0.981108515514857 0.981108515514857
Capn2 ENSMUSG00000026509 0.746187747633598 0.773247051273166 0.296497506886398 0.773247051273166 0.773247051273166 0.773247051273166
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Thbs3 ENSMUSG00000028047 0.788372131560243 0.788372131560243 0.666942932606772 0.788372131560243 0.269790263619584 0.788372131560243
Col9a2 ENSMUSG00000028626 0.717182266053983 0.85480012261282 0.85480012261282 0.85480012261282 0.577044549040291 0.85480012261282
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Pak1 ENSMUSG00000030774 0.955926394457724 0.955926394457724 0.940206714909191 0.955926394457724 0.890125073099196 0.955926394457724
Col4a6 ENSMUSG00000031273 0.384104158371494 0.766743553616261 0.96846938071278 0.96846938071278 0.511162369077507 0.766743553616261
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Shc4 ENSMUSG00000035109 0.431390413009988 0.647085619514982 0.373786191263948 0.647085619514982 0.883847376802966 0.883847376802966
Pak7 ENSMUSG00000039913 0.594969319883574 0.948939766320461 0.881149414868131 0.948939766320461 0.948939766320461 0.948939766320461
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Mapk10 ENSMUSG00000046709 0.880649991049328 0.955896711562292 0.955896711562292 0.955896711562292 0.843535096975309 0.955896711562292
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Prkca ENSMUSG00000050965 0.580384068270434 0.918271134239714 0.918271134239714 0.918271134239714 0.828153008953029 0.918271134239714
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Pak6 ENSMUSG00000074923 0.320780926597679 0.898839487095189 0.599226324730126 0.898839487095189 0.96534841382286 0.96534841382286
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Neuronal System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnn3 ENSMUSG00000000794 0.980981585411957 0.980981585411957 0.670545128861312 0.980981585411957 0.649193834819889 0.980981585411957
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Dlgap1 ENSMUSG00000003279 0.914181497561351 0.914181497561351 0.62518185785014 0.914181497561351 0.694130083855431 0.914181497561351
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Lin7b ENSMUSG00000003872 0.99053377424718 0.99053377424718 0.475776997795139 0.99053377424718 0.689194048568042 0.99053377424718
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Homer1 ENSMUSG00000007617 0.317201338024321 0.943369538436606 0.943369538436606 0.943369538436606 0.797512319691107 0.943369538436606
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Syn2 ENSMUSG00000009394 0.825050389878912 0.825050389878912 0.404423231124745 0.825050389878912 0.821990181966326 0.825050389878912
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Ptprs ENSMUSG00000013236 0.943368755766956 0.943368755766956 0.684301361214679 0.943368755766956 0.794480068246185 0.943368755766956
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Lin7a ENSMUSG00000019906 0.200912177596541 0.602736532789624 0.852833451835089 0.852833451835089 0.834253661956003 0.852833451835089
Hcn2 ENSMUSG00000020331 0.534981328000019 0.577729520726797 0.283774858742742 0.577729520726797 0.577729520726797 0.577729520726797
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Akap5 ENSMUSG00000021057 0.607590203677987 0.958974394225523 0.861726528780859 0.958974394225523 0.958974394225523 0.958974394225523
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Hcn1 ENSMUSG00000021730 0.553676440072061 0.767040125638078 0.716868545276752 0.767040125638078 0.767040125638078 0.767040125638078
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Nrxn1 ENSMUSG00000024109 0.279779262365715 0.839337787097145 0.852677270554343 0.852677270554343 0.834258443605675 0.852677270554343
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Rtn3 ENSMUSG00000024758 0.583066701310634 0.672722108342328 0.672722108342328 0.672722108342328 0.616070574472783 0.672722108342328
Apba1 ENSMUSG00000024897 0.610210970555765 0.886954424019127 0.886954424019127 0.886954424019127 0.809448506135601 0.886954424019127
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Homer2 ENSMUSG00000025813 0.509499642036776 0.918259619702903 0.918259619702903 0.918259619702903 0.661172737615778 0.918259619702903
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Glul ENSMUSG00000026473 0.56159503256356 0.710595323259519 0.285656307463184 0.710595323259519 0.710595323259519 0.710595323259519
Gad2 ENSMUSG00000026787 0.62440231835418 0.88663582819218 0.698820798936253 0.88663582819218 0.88663582819218 0.88663582819218
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Kcnab1 ENSMUSG00000027827 0.902622758045388 0.902622758045388 0.855866651765956 0.902622758045388 0.309366622023708 0.902622758045388
Kcnc4 ENSMUSG00000027895 0.926990256850779 0.930225318619583 0.930225318619583 0.930225318619583 0.877311782342819 0.930225318619583
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Glrb ENSMUSG00000028020 0.262405896861402 0.629781498969239 0.610314670165233 0.629781498969239 0.629781498969239 0.629781498969239
Kcnq5 ENSMUSG00000028033 0.917881150154338 0.974704933577623 0.974704933577623 0.974704933577623 0.95254419357626 0.974704933577623
Hcn3 ENSMUSG00000028051 0.771909102869138 0.867541689745964 0.627079137728601 0.867541689745964 0.867541689745964 0.867541689745964
Ptprd ENSMUSG00000028399 0.459966705443304 0.689950058164955 0.393236199340387 0.689950058164955 0.990549881514966 0.990549881514966
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Kcnab2 ENSMUSG00000028931 0.828093061385086 0.902590609588304 0.902590609588304 0.902590609588304 0.516870066705894 0.902590609588304
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Lrfn1 ENSMUSG00000030600 0.310908914570263 0.724844700236989 0.663998488002603 0.724844700236989 0.724844700236989 0.724844700236989
Nlgn3 ENSMUSG00000031302 0.834261108009541 0.834261108009541 0.663687609645552 0.834261108009541 0.73149757680789 0.834261108009541
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Slitrk5 ENSMUSG00000033214 0.954301730371711 0.954301730371711 0.696543180488229 0.954301730371711 0.810175314718082 0.954301730371711
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Nrxn2 ENSMUSG00000033768 0.862104740999051 0.984252983296475 0.984252983296475 0.984252983296475 0.734163734122391 0.984252983296475
Kcnk10 ENSMUSG00000033854 0.66478227229457 0.943076748487154 0.943076748487154 0.943076748487154 0.75383616685965 0.943076748487154
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Kcnh4 ENSMUSG00000035355 0.788390463417217 0.973653493023554 0.963700661237279 0.973653493023554 0.973653493023554 0.973653493023554
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Aldh5a1 ENSMUSG00000035936 0.698856351817522 0.731292199827224 0.506993720611274 0.731292199827224 0.731292199827224 0.731292199827224
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Slitrk2 ENSMUSG00000036790 0.707265538443087 0.936303643579166 0.828874618019525 0.936303643579166 0.936303643579166 0.936303643579166
Lrfn3 ENSMUSG00000036957 0.604987519117908 0.604987519117908 0.514619623793571 0.604987519117908 0.602236675307848 0.604987519117908
Syn1 ENSMUSG00000037217 0.755949027846733 0.820240065938674 0.567111127742349 0.820240065938674 0.820240065938674 0.820240065938674
Shank2 ENSMUSG00000037541 0.794349094947865 0.794349094947865 0.757514923991936 0.794349094947865 0.75449015233661 0.794349094947865
Kcnh3 ENSMUSG00000037579 0.523167998706008 0.936021099437487 0.797220237348694 0.936021099437487 0.936021099437487 0.936021099437487
Kcnmb2 ENSMUSG00000037610 0.916247831827169 0.932300307938558 0.932300307938558 0.932300307938558 0.764799797741101 0.932300307938558
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Kcna6 ENSMUSG00000038077 0.471092655006258 0.706638982509388 0.336251463693341 0.706638982509388 0.904466929872425 0.904466929872425
Shank1 ENSMUSG00000038738 0.517084919638398 0.845614104820268 0.793854460752608 0.845614104820268 0.845614104820268 0.845614104820268
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Kcns1 ENSMUSG00000040164 0.948457476746691 0.948457476746691 0.802111171649886 0.948457476746691 0.746100429276895 0.948457476746691
Lrfn2 ENSMUSG00000040490 0.920438328751921 0.9677823270887 0.653558718678658 0.9677823270887 0.9677823270887 0.9677823270887
Kcna2 ENSMUSG00000040724 0.66480751569452 0.95865797589942 0.786681850236461 0.95865797589942 0.95865797589942 0.95865797589942
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Dlgap3 ENSMUSG00000042388 0.863461127101176 0.863461127101176 0.750811930063077 0.863461127101176 0.840726729844657 0.863461127101176
Kcna4 ENSMUSG00000042604 0.970307380221167 0.970307380221167 0.953991553652117 0.970307380221167 0.651894885265634 0.970307380221167
Lrrtm3 ENSMUSG00000042846 0.936230066117832 0.936230066117832 0.860669208580973 0.936230066117832 0.752900782520132 0.936230066117832
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Lrfn4 ENSMUSG00000045045 0.509384966172034 0.918235610892621 0.918235610892621 0.918235610892621 0.725273295524725 0.918235610892621
Kcng3 ENSMUSG00000045053 0.272060847469607 0.527967370292345 0.432172634456493 0.527967370292345 0.527967370292345 0.527967370292345
Slitrk4 ENSMUSG00000046699 0.453461673413167 0.954643989995591 0.954643989995591 0.954643989995591 0.927969965345874 0.954643989995591
Lrrc4b ENSMUSG00000047085 0.580727279922867 0.939134465864034 0.939134465864034 0.939134465864034 0.760107131568757 0.939134465864034
Kcna1 ENSMUSG00000047976 0.598923477446711 0.886415222630142 0.855126238826804 0.886415222630142 0.886415222630142 0.886415222630142
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Slitrk3 ENSMUSG00000048304 0.614670646547173 0.993391837135839 0.782152084098795 0.993391837135839 0.993391837135839 0.993391837135839
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Nlgn2 ENSMUSG00000051790 0.550986134941578 0.58308068198293 0.58308068198293 0.58308068198293 0.537847802454335 0.58308068198293
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Kcnn2 ENSMUSG00000054477 0.990553175175274 0.990553175175274 0.862134088048948 0.990553175175274 0.779274644686567 0.990553175175274
Kcnmb4 ENSMUSG00000054934 0.814060002714044 0.923634124055874 0.923634124055874 0.923634124055874 0.760665245028893 0.923634124055874
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Kcnq3 ENSMUSG00000056258 0.52812822993625 0.990176738721108 0.97033866766767 0.990176738721108 0.990176738721108 0.990176738721108
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Panx2 ENSMUSG00000058441 0.893774471748796 0.922995104717142 0.922995104717142 0.922995104717142 0.821377437619042 0.922995104717142
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Kcnc1 ENSMUSG00000058975 0.930645176497891 0.962010301049401 0.962010301049401 0.962010301049401 0.861431027952089 0.962010301049401
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Ntrk3 ENSMUSG00000059146 0.899407856512363 0.899407856512363 0.695722258925379 0.899407856512363 0.657950245869533 0.899407856512363
Syn3 ENSMUSG00000059602 0.7812836618396 0.7812836618396 0.630828775334128 0.7812836618396 0.710244967230379 0.7812836618396
Flot1 ENSMUSG00000059714 0.4022016946755 0.603302542013251 0.229028103922559 0.603302542013251 0.773247937931798 0.773247937931798
Kcnh7 ENSMUSG00000059742 0.909618779114654 0.909618779114654 0.890226192518892 0.909618779114654 0.902584179745889 0.909618779114654
Lrrtm1 ENSMUSG00000060780 0.906221203048234 0.906221203048234 0.723572275273988 0.906221203048234 0.589235566839666 0.906221203048234
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Flot2 ENSMUSG00000061981 0.46733854475993 0.701007817139895 0.244801647402033 0.701007817139895 0.974813100222686 0.974813100222686
Kcnc3 ENSMUSG00000062785 0.264606770689471 0.548079307222063 0.365386204814709 0.548079307222063 0.79447941759174 0.79447941759174
Nlgn1 ENSMUSG00000063887 0.474099503319141 0.848325369786747 0.772171931442803 0.848325369786747 0.848325369786747 0.848325369786747
Nrxn3 ENSMUSG00000066392 0.610968260752645 0.610968260752645 0.255408619944771 0.610968260752645 0.478572718844866 0.610968260752645
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gad1 ENSMUSG00000070880 0.768676916415066 0.936959438615519 0.936959438615519 0.936959438615519 0.829955651614648 0.936959438615519
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Lrrtm2 ENSMUSG00000071862 0.303392743346899 0.910178230040697 0.966526589044775 1 1 1
Kcng1 ENSMUSG00000074575 0.686536949156563 0.801105765787366 0.801105765787366 0.801105765787366 0.720747382481534 0.801105765787366
Slitrk1 ENSMUSG00000075478 0.693232378264004 0.780170177965392 0.669321443154951 0.780170177965392 0.780170177965392 0.780170177965392
Tomt ENSMUSG00000078630 0.702003199818379 0.837360622354244 0.837360622354244 0.837360622354244 0.683928196153426 0.837360622354244
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Transmission across Chemical Synapses

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Lin7b ENSMUSG00000003872 0.99053377424718 0.99053377424718 0.475776997795139 0.99053377424718 0.689194048568042 0.99053377424718
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Syn2 ENSMUSG00000009394 0.825050389878912 0.825050389878912 0.404423231124745 0.825050389878912 0.821990181966326 0.825050389878912
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Lin7a ENSMUSG00000019906 0.200912177596541 0.602736532789624 0.852833451835089 0.852833451835089 0.834253661956003 0.852833451835089
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Akap5 ENSMUSG00000021057 0.607590203677987 0.958974394225523 0.861726528780859 0.958974394225523 0.958974394225523 0.958974394225523
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Apba1 ENSMUSG00000024897 0.610210970555765 0.886954424019127 0.886954424019127 0.886954424019127 0.809448506135601 0.886954424019127
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Glul ENSMUSG00000026473 0.56159503256356 0.710595323259519 0.285656307463184 0.710595323259519 0.710595323259519 0.710595323259519
Gad2 ENSMUSG00000026787 0.62440231835418 0.88663582819218 0.698820798936253 0.88663582819218 0.88663582819218 0.88663582819218
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Glrb ENSMUSG00000028020 0.262405896861402 0.629781498969239 0.610314670165233 0.629781498969239 0.629781498969239 0.629781498969239
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Aldh5a1 ENSMUSG00000035936 0.698856351817522 0.731292199827224 0.506993720611274 0.731292199827224 0.731292199827224 0.731292199827224
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Syn1 ENSMUSG00000037217 0.755949027846733 0.820240065938674 0.567111127742349 0.820240065938674 0.820240065938674 0.820240065938674
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Syn3 ENSMUSG00000059602 0.7812836618396 0.7812836618396 0.630828775334128 0.7812836618396 0.710244967230379 0.7812836618396
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gad1 ENSMUSG00000070880 0.768676916415066 0.936959438615519 0.936959438615519 0.936959438615519 0.829955651614648 0.936959438615519
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Tomt ENSMUSG00000078630 0.702003199818379 0.837360622354244 0.837360622354244 0.837360622354244 0.683928196153426 0.837360622354244
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Protein-protein interactions at synapses

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Dlgap1 ENSMUSG00000003279 0.914181497561351 0.914181497561351 0.62518185785014 0.914181497561351 0.694130083855431 0.914181497561351
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Homer1 ENSMUSG00000007617 0.317201338024321 0.943369538436606 0.943369538436606 0.943369538436606 0.797512319691107 0.943369538436606
Ptprs ENSMUSG00000013236 0.943368755766956 0.943368755766956 0.684301361214679 0.943368755766956 0.794480068246185 0.943368755766956
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Nrxn1 ENSMUSG00000024109 0.279779262365715 0.839337787097145 0.852677270554343 0.852677270554343 0.834258443605675 0.852677270554343
Rtn3 ENSMUSG00000024758 0.583066701310634 0.672722108342328 0.672722108342328 0.672722108342328 0.616070574472783 0.672722108342328
Homer2 ENSMUSG00000025813 0.509499642036776 0.918259619702903 0.918259619702903 0.918259619702903 0.661172737615778 0.918259619702903
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptprd ENSMUSG00000028399 0.459966705443304 0.689950058164955 0.393236199340387 0.689950058164955 0.990549881514966 0.990549881514966
Lrfn1 ENSMUSG00000030600 0.310908914570263 0.724844700236989 0.663998488002603 0.724844700236989 0.724844700236989 0.724844700236989
Nlgn3 ENSMUSG00000031302 0.834261108009541 0.834261108009541 0.663687609645552 0.834261108009541 0.73149757680789 0.834261108009541
Slitrk5 ENSMUSG00000033214 0.954301730371711 0.954301730371711 0.696543180488229 0.954301730371711 0.810175314718082 0.954301730371711
Nrxn2 ENSMUSG00000033768 0.862104740999051 0.984252983296475 0.984252983296475 0.984252983296475 0.734163734122391 0.984252983296475
Slitrk2 ENSMUSG00000036790 0.707265538443087 0.936303643579166 0.828874618019525 0.936303643579166 0.936303643579166 0.936303643579166
Lrfn3 ENSMUSG00000036957 0.604987519117908 0.604987519117908 0.514619623793571 0.604987519117908 0.602236675307848 0.604987519117908
Shank2 ENSMUSG00000037541 0.794349094947865 0.794349094947865 0.757514923991936 0.794349094947865 0.75449015233661 0.794349094947865
Shank1 ENSMUSG00000038738 0.517084919638398 0.845614104820268 0.793854460752608 0.845614104820268 0.845614104820268 0.845614104820268
Lrfn2 ENSMUSG00000040490 0.920438328751921 0.9677823270887 0.653558718678658 0.9677823270887 0.9677823270887 0.9677823270887
Dlgap3 ENSMUSG00000042388 0.863461127101176 0.863461127101176 0.750811930063077 0.863461127101176 0.840726729844657 0.863461127101176
Lrrtm3 ENSMUSG00000042846 0.936230066117832 0.936230066117832 0.860669208580973 0.936230066117832 0.752900782520132 0.936230066117832
Lrfn4 ENSMUSG00000045045 0.509384966172034 0.918235610892621 0.918235610892621 0.918235610892621 0.725273295524725 0.918235610892621
Slitrk4 ENSMUSG00000046699 0.453461673413167 0.954643989995591 0.954643989995591 0.954643989995591 0.927969965345874 0.954643989995591
Lrrc4b ENSMUSG00000047085 0.580727279922867 0.939134465864034 0.939134465864034 0.939134465864034 0.760107131568757 0.939134465864034
Slitrk3 ENSMUSG00000048304 0.614670646547173 0.993391837135839 0.782152084098795 0.993391837135839 0.993391837135839 0.993391837135839
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Nlgn2 ENSMUSG00000051790 0.550986134941578 0.58308068198293 0.58308068198293 0.58308068198293 0.537847802454335 0.58308068198293
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Ntrk3 ENSMUSG00000059146 0.899407856512363 0.899407856512363 0.695722258925379 0.899407856512363 0.657950245869533 0.899407856512363
Flot1 ENSMUSG00000059714 0.4022016946755 0.603302542013251 0.229028103922559 0.603302542013251 0.773247937931798 0.773247937931798
Lrrtm1 ENSMUSG00000060780 0.906221203048234 0.906221203048234 0.723572275273988 0.906221203048234 0.589235566839666 0.906221203048234
Flot2 ENSMUSG00000061981 0.46733854475993 0.701007817139895 0.244801647402033 0.701007817139895 0.974813100222686 0.974813100222686
Nlgn1 ENSMUSG00000063887 0.474099503319141 0.848325369786747 0.772171931442803 0.848325369786747 0.848325369786747 0.848325369786747
Nrxn3 ENSMUSG00000066392 0.610968260752645 0.610968260752645 0.255408619944771 0.610968260752645 0.478572718844866 0.610968260752645
Lrrtm2 ENSMUSG00000071862 0.303392743346899 0.910178230040697 0.966526589044775 1 1 1
Slitrk1 ENSMUSG00000075478 0.693232378264004 0.780170177965392 0.669321443154951 0.780170177965392 0.780170177965392 0.780170177965392

Neurotransmitter receptors and postsynaptic signal transmission

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Akap5 ENSMUSG00000021057 0.607590203677987 0.958974394225523 0.861726528780859 0.958974394225523 0.958974394225523 0.958974394225523
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Chrnb2 ENSMUSG00000027950 0.776256598397219 0.776256598397219 0.725353423515211 0.776256598397219 0.524828301931153 0.776256598397219
Glrb ENSMUSG00000028020 0.262405896861402 0.629781498969239 0.610314670165233 0.629781498969239 0.629781498969239 0.629781498969239
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Chrna7 ENSMUSG00000030525 0.875837283395332 0.912858747737092 0.592362315095553 0.912858747737092 0.912858747737092 0.912858747737092
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Potassium Channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnn3 ENSMUSG00000000794 0.980981585411957 0.980981585411957 0.670545128861312 0.980981585411957 0.649193834819889 0.980981585411957
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Hcn2 ENSMUSG00000020331 0.534981328000019 0.577729520726797 0.283774858742742 0.577729520726797 0.577729520726797 0.577729520726797
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Hcn1 ENSMUSG00000021730 0.553676440072061 0.767040125638078 0.716868545276752 0.767040125638078 0.767040125638078 0.767040125638078
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Kcnab1 ENSMUSG00000027827 0.902622758045388 0.902622758045388 0.855866651765956 0.902622758045388 0.309366622023708 0.902622758045388
Kcnc4 ENSMUSG00000027895 0.926990256850779 0.930225318619583 0.930225318619583 0.930225318619583 0.877311782342819 0.930225318619583
Kcnq5 ENSMUSG00000028033 0.917881150154338 0.974704933577623 0.974704933577623 0.974704933577623 0.95254419357626 0.974704933577623
Hcn3 ENSMUSG00000028051 0.771909102869138 0.867541689745964 0.627079137728601 0.867541689745964 0.867541689745964 0.867541689745964
Kcnab2 ENSMUSG00000028931 0.828093061385086 0.902590609588304 0.902590609588304 0.902590609588304 0.516870066705894 0.902590609588304
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnk10 ENSMUSG00000033854 0.66478227229457 0.943076748487154 0.943076748487154 0.943076748487154 0.75383616685965 0.943076748487154
Kcnh4 ENSMUSG00000035355 0.788390463417217 0.973653493023554 0.963700661237279 0.973653493023554 0.973653493023554 0.973653493023554
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Kcnh3 ENSMUSG00000037579 0.523167998706008 0.936021099437487 0.797220237348694 0.936021099437487 0.936021099437487 0.936021099437487
Kcnmb2 ENSMUSG00000037610 0.916247831827169 0.932300307938558 0.932300307938558 0.932300307938558 0.764799797741101 0.932300307938558
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Kcna6 ENSMUSG00000038077 0.471092655006258 0.706638982509388 0.336251463693341 0.706638982509388 0.904466929872425 0.904466929872425
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Kcns1 ENSMUSG00000040164 0.948457476746691 0.948457476746691 0.802111171649886 0.948457476746691 0.746100429276895 0.948457476746691
Kcna2 ENSMUSG00000040724 0.66480751569452 0.95865797589942 0.786681850236461 0.95865797589942 0.95865797589942 0.95865797589942
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Kcna4 ENSMUSG00000042604 0.970307380221167 0.970307380221167 0.953991553652117 0.970307380221167 0.651894885265634 0.970307380221167
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Kcng3 ENSMUSG00000045053 0.272060847469607 0.527967370292345 0.432172634456493 0.527967370292345 0.527967370292345 0.527967370292345
Kcna1 ENSMUSG00000047976 0.598923477446711 0.886415222630142 0.855126238826804 0.886415222630142 0.886415222630142 0.886415222630142
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Kcnn2 ENSMUSG00000054477 0.990553175175274 0.990553175175274 0.862134088048948 0.990553175175274 0.779274644686567 0.990553175175274
Kcnmb4 ENSMUSG00000054934 0.814060002714044 0.923634124055874 0.923634124055874 0.923634124055874 0.760665245028893 0.923634124055874
Kcnq3 ENSMUSG00000056258 0.52812822993625 0.990176738721108 0.97033866766767 0.990176738721108 0.990176738721108 0.990176738721108
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Kcnc1 ENSMUSG00000058975 0.930645176497891 0.962010301049401 0.962010301049401 0.962010301049401 0.861431027952089 0.962010301049401
Kcnh7 ENSMUSG00000059742 0.909618779114654 0.909618779114654 0.890226192518892 0.909618779114654 0.902584179745889 0.909618779114654
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Kcnc3 ENSMUSG00000062785 0.264606770689471 0.548079307222063 0.365386204814709 0.548079307222063 0.79447941759174 0.79447941759174
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Kcng1 ENSMUSG00000074575 0.686536949156563 0.801105765787366 0.801105765787366 0.801105765787366 0.720747382481534 0.801105765787366

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Grb10 ENSMUSG00000020176 0.862131756215552 0.862131756215552 0.326849349555167 0.862131756215552 0.725321363060051 0.862131756215552
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Trem2 ENSMUSG00000023992 0.675571492686183 0.871308680119938 0.871308680119938 0.871308680119938 0.454725265732204 0.871308680119938
Dpysl3 ENSMUSG00000024501 0.455246018180067 0.803607788697596 0.803607788697596 0.803607788697596 0.661217288805153 0.803607788697596
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
St8sia2 ENSMUSG00000025789 0.424675931893258 0.74496319565452 0.66720559161028 0.74496319565452 0.74496319565452 0.74496319565452
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Unc5a ENSMUSG00000025876 0.812552222144865 0.812552222144865 0.767074155135085 0.812552222144865 0.704363534681499 0.812552222144865
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Nfasc ENSMUSG00000026442 0.698355335532337 0.698355335532337 0.646491985253954 0.698355335532337 0.660344021623246 0.698355335532337
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Dok5 ENSMUSG00000027560 0.752557960971498 0.752557960971498 0.735789387224965 0.752557960971498 0.655254834944887 0.752557960971498
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Sh3gl2 ENSMUSG00000028488 0.968519675120957 0.968519675120957 0.831222278599938 0.968519675120957 0.815862937084519 0.968519675120957
Dab1 ENSMUSG00000028519 0.911931053123151 0.911931053123151 0.666573021804146 0.911931053123151 0.643795719176379 0.911931053123151
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Crmp1 ENSMUSG00000029121 0.974780940800692 0.974780940800692 0.703852424803108 0.974780940800692 0.716019435270133 0.974780940800692
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Plxnb3 ENSMUSG00000031385 0.858919312754963 0.858919312754963 0.311087152421553 0.661320759556636 0.44088050637109 0.661320759556636
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Slit2 ENSMUSG00000031558 0.687185789711974 0.930806648357942 0.930806648357942 0.930806648357942 0.890126121650186 0.930806648357942
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Dscaml1 ENSMUSG00000032087 0.743624103954924 0.879546593432192 0.879546593432192 0.879546593432192 0.755383506167265 0.879546593432192
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Rap1gap ENSMUSG00000041351 0.874516196622842 0.883872708327981 0.78529204277281 0.883872708327981 0.883872708327981 0.883872708327981
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Gap43 ENSMUSG00000047261 0.993653299594886 0.993653299594886 0.765673954326294 0.993653299594886 0.965217607319514 0.993653299594886
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Dscam ENSMUSG00000050272 0.951102378539934 0.951102378539934 0.869577730490515 0.951102378539934 0.654053762644395 0.951102378539934
Cntn2 ENSMUSG00000053024 0.946920054315675 0.946920054315675 0.718580352683058 0.946920054315675 0.560606666115818 0.946920054315675
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rhob ENSMUSG00000054364 0.627229077552181 0.927675553302141 0.104015613170298 0.312046839510893 0.927675553302141 0.927675553302141
Rnd1 ENSMUSG00000054855 0.661203233113187 0.661203233113187 0.298379466146235 0.661203233113187 0.627172996382542 0.661203233113187
Slit3 ENSMUSG00000056427 0.89318101208312 0.918220401047043 0.704618619398227 0.918220401047043 0.918220401047043 0.918220401047043
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sema3e ENSMUSG00000063531 0.667952496734551 0.700802645980391 0.700802645980391 0.700802645980391 0.583640050957042 0.700802645980391
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Nervous system development

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Grb10 ENSMUSG00000020176 0.862131756215552 0.862131756215552 0.326849349555167 0.862131756215552 0.725321363060051 0.862131756215552
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Trem2 ENSMUSG00000023992 0.675571492686183 0.871308680119938 0.871308680119938 0.871308680119938 0.454725265732204 0.871308680119938
Dpysl3 ENSMUSG00000024501 0.455246018180067 0.803607788697596 0.803607788697596 0.803607788697596 0.661217288805153 0.803607788697596
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
St8sia2 ENSMUSG00000025789 0.424675931893258 0.74496319565452 0.66720559161028 0.74496319565452 0.74496319565452 0.74496319565452
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Unc5a ENSMUSG00000025876 0.812552222144865 0.812552222144865 0.767074155135085 0.812552222144865 0.704363534681499 0.812552222144865
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Nfasc ENSMUSG00000026442 0.698355335532337 0.698355335532337 0.646491985253954 0.698355335532337 0.660344021623246 0.698355335532337
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Dok5 ENSMUSG00000027560 0.752557960971498 0.752557960971498 0.735789387224965 0.752557960971498 0.655254834944887 0.752557960971498
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Sh3gl2 ENSMUSG00000028488 0.968519675120957 0.968519675120957 0.831222278599938 0.968519675120957 0.815862937084519 0.968519675120957
Dab1 ENSMUSG00000028519 0.911931053123151 0.911931053123151 0.666573021804146 0.911931053123151 0.643795719176379 0.911931053123151
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Crmp1 ENSMUSG00000029121 0.974780940800692 0.974780940800692 0.703852424803108 0.974780940800692 0.716019435270133 0.974780940800692
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Plxnb3 ENSMUSG00000031385 0.858919312754963 0.858919312754963 0.311087152421553 0.661320759556636 0.44088050637109 0.661320759556636
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Slit2 ENSMUSG00000031558 0.687185789711974 0.930806648357942 0.930806648357942 0.930806648357942 0.890126121650186 0.930806648357942
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Dscaml1 ENSMUSG00000032087 0.743624103954924 0.879546593432192 0.879546593432192 0.879546593432192 0.755383506167265 0.879546593432192
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Rap1gap ENSMUSG00000041351 0.874516196622842 0.883872708327981 0.78529204277281 0.883872708327981 0.883872708327981 0.883872708327981
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Gap43 ENSMUSG00000047261 0.993653299594886 0.993653299594886 0.765673954326294 0.993653299594886 0.965217607319514 0.993653299594886
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Dscam ENSMUSG00000050272 0.951102378539934 0.951102378539934 0.869577730490515 0.951102378539934 0.654053762644395 0.951102378539934
Cntn2 ENSMUSG00000053024 0.946920054315675 0.946920054315675 0.718580352683058 0.946920054315675 0.560606666115818 0.946920054315675
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rhob ENSMUSG00000054364 0.627229077552181 0.927675553302141 0.104015613170298 0.312046839510893 0.927675553302141 0.927675553302141
Rnd1 ENSMUSG00000054855 0.661203233113187 0.661203233113187 0.298379466146235 0.661203233113187 0.627172996382542 0.661203233113187
Slit3 ENSMUSG00000056427 0.89318101208312 0.918220401047043 0.704618619398227 0.918220401047043 0.918220401047043 0.918220401047043
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sema3e ENSMUSG00000063531 0.667952496734551 0.700802645980391 0.700802645980391 0.700802645980391 0.583640050957042 0.700802645980391
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Synaptic adhesion-like molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ptprs ENSMUSG00000013236 0.943368755766956 0.943368755766956 0.684301361214679 0.943368755766956 0.794480068246185 0.943368755766956
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Rtn3 ENSMUSG00000024758 0.583066701310634 0.672722108342328 0.672722108342328 0.672722108342328 0.616070574472783 0.672722108342328
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptprd ENSMUSG00000028399 0.459966705443304 0.689950058164955 0.393236199340387 0.689950058164955 0.990549881514966 0.990549881514966
Lrfn1 ENSMUSG00000030600 0.310908914570263 0.724844700236989 0.663998488002603 0.724844700236989 0.724844700236989 0.724844700236989
Lrfn3 ENSMUSG00000036957 0.604987519117908 0.604987519117908 0.514619623793571 0.604987519117908 0.602236675307848 0.604987519117908
Lrfn2 ENSMUSG00000040490 0.920438328751921 0.9677823270887 0.653558718678658 0.9677823270887 0.9677823270887 0.9677823270887
Lrfn4 ENSMUSG00000045045 0.509384966172034 0.918235610892621 0.918235610892621 0.918235610892621 0.725273295524725 0.918235610892621
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798
Flot1 ENSMUSG00000059714 0.4022016946755 0.603302542013251 0.229028103922559 0.603302542013251 0.773247937931798 0.773247937931798
Flot2 ENSMUSG00000061981 0.46733854475993 0.701007817139895 0.244801647402033 0.701007817139895 0.974813100222686 0.974813100222686

Activation of NMDA receptors and postsynaptic events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798

Cardiac conduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Fkbp1b ENSMUSG00000020635 0.67838623943518 0.94020814846731 0.734102818928033 0.94020814846731 0.94020814846731 0.94020814846731
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf12 ENSMUSG00000022523 0.735481651893555 0.939219949131427 0.939219949131427 0.939219949131427 0.862494288944481 0.939219949131427
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Kcnip2 ENSMUSG00000025221 0.865138946399732 0.865138946399732 0.535031755209987 0.865138946399732 0.803454707196558 0.865138946399732
Nppc ENSMUSG00000026241 0.609483026562215 0.93866457594603 0.785247476100659 0.93866457594603 0.93866457594603 0.93866457594603
Ahcyl1 ENSMUSG00000027893 0.803585201781793 0.977953489783539 0.977953489783539 0.977953489783539 0.737175540269971 0.977953489783539
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Kcnip4 ENSMUSG00000029088 0.445077599944986 0.759159395757576 0.612008419684874 0.759159395757576 0.759159395757576 0.759159395757576
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Kcnk10 ENSMUSG00000033854 0.66478227229457 0.943076748487154 0.943076748487154 0.943076748487154 0.75383616685965 0.943076748487154
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fxyd7 ENSMUSG00000036578 0.429266975420368 0.6103666140928 0.342717167898781 0.6103666140928 0.6103666140928 0.6103666140928
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Fgf11 ENSMUSG00000042826 0.585544643476472 0.955895923008687 0.821869550022072 0.955895923008687 0.955895923008687 0.955895923008687
Scn3b ENSMUSG00000049281 0.30654479948407 0.919634398452211 0.793926536833379 0.946452571395267 0.946452571395267 0.946452571395267
Kcnip1 ENSMUSG00000053519 0.790322545695729 0.824156296127533 0.799357591994899 0.824156296127533 0.824156296127533 0.824156296127533
Scn3a ENSMUSG00000057182 0.549822880279604 0.742640594103942 0.686490207224732 0.742640594103942 0.742640594103942 0.742640594103942
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Scn1a ENSMUSG00000064329 0.228565863853541 0.685697591560622 0.554070895749723 0.744924725900363 0.744924725900363 0.744924725900363
Fxyd6 ENSMUSG00000066705 0.604968393504201 0.644142732695471 0.37816156867391 0.644142732695471 0.644142732695471 0.644142732695471
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Scn2b ENSMUSG00000070304 0.915003003694042 0.915003003694042 0.877642871861204 0.915003003694042 0.794197034769996 0.915003003694042
Scn2a1 ENSMUSG00000075318 0.19651465329244 0.58954395987732 0.919475212271158 0.919475212271158 0.878320961398532 0.919475212271158
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504
Kcnip3 ENSMUSG00000079056 0.959050310271809 0.959050310271809 0.615797298690923 0.959050310271809 0.930753732572343 0.959050310271809
Kcne1l ENSMUSG00000090122 0.943035949081477 0.987341532095268 0.920964728986533 0.987341532095268 0.987341532095268 0.987341532095268

Voltage gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Kcnab1 ENSMUSG00000027827 0.902622758045388 0.902622758045388 0.855866651765956 0.902622758045388 0.309366622023708 0.902622758045388
Kcnc4 ENSMUSG00000027895 0.926990256850779 0.930225318619583 0.930225318619583 0.930225318619583 0.877311782342819 0.930225318619583
Kcnq5 ENSMUSG00000028033 0.917881150154338 0.974704933577623 0.974704933577623 0.974704933577623 0.95254419357626 0.974704933577623
Kcnab2 ENSMUSG00000028931 0.828093061385086 0.902590609588304 0.902590609588304 0.902590609588304 0.516870066705894 0.902590609588304
Kcnh4 ENSMUSG00000035355 0.788390463417217 0.973653493023554 0.963700661237279 0.973653493023554 0.973653493023554 0.973653493023554
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Kcnh3 ENSMUSG00000037579 0.523167998706008 0.936021099437487 0.797220237348694 0.936021099437487 0.936021099437487 0.936021099437487
Kcna6 ENSMUSG00000038077 0.471092655006258 0.706638982509388 0.336251463693341 0.706638982509388 0.904466929872425 0.904466929872425
Kcns1 ENSMUSG00000040164 0.948457476746691 0.948457476746691 0.802111171649886 0.948457476746691 0.746100429276895 0.948457476746691
Kcna2 ENSMUSG00000040724 0.66480751569452 0.95865797589942 0.786681850236461 0.95865797589942 0.95865797589942 0.95865797589942
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Kcna4 ENSMUSG00000042604 0.970307380221167 0.970307380221167 0.953991553652117 0.970307380221167 0.651894885265634 0.970307380221167
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Kcng3 ENSMUSG00000045053 0.272060847469607 0.527967370292345 0.432172634456493 0.527967370292345 0.527967370292345 0.527967370292345
Kcna1 ENSMUSG00000047976 0.598923477446711 0.886415222630142 0.855126238826804 0.886415222630142 0.886415222630142 0.886415222630142
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Kcnq3 ENSMUSG00000056258 0.52812822993625 0.990176738721108 0.97033866766767 0.990176738721108 0.990176738721108 0.990176738721108
Kcnc1 ENSMUSG00000058975 0.930645176497891 0.962010301049401 0.962010301049401 0.962010301049401 0.861431027952089 0.962010301049401
Kcnh7 ENSMUSG00000059742 0.909618779114654 0.909618779114654 0.890226192518892 0.909618779114654 0.902584179745889 0.909618779114654
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Kcnc3 ENSMUSG00000062785 0.264606770689471 0.548079307222063 0.365386204814709 0.548079307222063 0.79447941759174 0.79447941759174
Kcng1 ENSMUSG00000074575 0.686536949156563 0.801105765787366 0.801105765787366 0.801105765787366 0.720747382481534 0.801105765787366

Unblocking of NMDA receptors, glutamate binding and activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798

Neurexins and neuroligins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlgap1 ENSMUSG00000003279 0.914181497561351 0.914181497561351 0.62518185785014 0.914181497561351 0.694130083855431 0.914181497561351
Homer1 ENSMUSG00000007617 0.317201338024321 0.943369538436606 0.943369538436606 0.943369538436606 0.797512319691107 0.943369538436606
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Nrxn1 ENSMUSG00000024109 0.279779262365715 0.839337787097145 0.852677270554343 0.852677270554343 0.834258443605675 0.852677270554343
Homer2 ENSMUSG00000025813 0.509499642036776 0.918259619702903 0.918259619702903 0.918259619702903 0.661172737615778 0.918259619702903
Nlgn3 ENSMUSG00000031302 0.834261108009541 0.834261108009541 0.663687609645552 0.834261108009541 0.73149757680789 0.834261108009541
Nrxn2 ENSMUSG00000033768 0.862104740999051 0.984252983296475 0.984252983296475 0.984252983296475 0.734163734122391 0.984252983296475
Shank2 ENSMUSG00000037541 0.794349094947865 0.794349094947865 0.757514923991936 0.794349094947865 0.75449015233661 0.794349094947865
Shank1 ENSMUSG00000038738 0.517084919638398 0.845614104820268 0.793854460752608 0.845614104820268 0.845614104820268 0.845614104820268
Dlgap3 ENSMUSG00000042388 0.863461127101176 0.863461127101176 0.750811930063077 0.863461127101176 0.840726729844657 0.863461127101176
Lrrtm3 ENSMUSG00000042846 0.936230066117832 0.936230066117832 0.860669208580973 0.936230066117832 0.752900782520132 0.936230066117832
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Nlgn2 ENSMUSG00000051790 0.550986134941578 0.58308068198293 0.58308068198293 0.58308068198293 0.537847802454335 0.58308068198293
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Lrrtm1 ENSMUSG00000060780 0.906221203048234 0.906221203048234 0.723572275273988 0.906221203048234 0.589235566839666 0.906221203048234
Nlgn1 ENSMUSG00000063887 0.474099503319141 0.848325369786747 0.772171931442803 0.848325369786747 0.848325369786747 0.848325369786747
Nrxn3 ENSMUSG00000066392 0.610968260752645 0.610968260752645 0.255408619944771 0.610968260752645 0.478572718844866 0.610968260752645
Lrrtm2 ENSMUSG00000071862 0.303392743346899 0.910178230040697 0.966526589044775 1 1 1

G-protein mediated events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Dopamine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Lin7b ENSMUSG00000003872 0.99053377424718 0.99053377424718 0.475776997795139 0.99053377424718 0.689194048568042 0.99053377424718
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Syn2 ENSMUSG00000009394 0.825050389878912 0.825050389878912 0.404423231124745 0.825050389878912 0.821990181966326 0.825050389878912
Lin7a ENSMUSG00000019906 0.200912177596541 0.602736532789624 0.852833451835089 0.852833451835089 0.834253661956003 0.852833451835089
Apba1 ENSMUSG00000024897 0.610210970555765 0.886954424019127 0.886954424019127 0.886954424019127 0.809448506135601 0.886954424019127
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Syn1 ENSMUSG00000037217 0.755949027846733 0.820240065938674 0.567111127742349 0.820240065938674 0.820240065938674 0.820240065938674
Syn3 ENSMUSG00000059602 0.7812836618396 0.7812836618396 0.630828775334128 0.7812836618396 0.710244967230379 0.7812836618396

Neurotransmitter release cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Lin7b ENSMUSG00000003872 0.99053377424718 0.99053377424718 0.475776997795139 0.99053377424718 0.689194048568042 0.99053377424718
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Syn2 ENSMUSG00000009394 0.825050389878912 0.825050389878912 0.404423231124745 0.825050389878912 0.821990181966326 0.825050389878912
Lin7a ENSMUSG00000019906 0.200912177596541 0.602736532789624 0.852833451835089 0.852833451835089 0.834253661956003 0.852833451835089
Apba1 ENSMUSG00000024897 0.610210970555765 0.886954424019127 0.886954424019127 0.886954424019127 0.809448506135601 0.886954424019127
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Gad2 ENSMUSG00000026787 0.62440231835418 0.88663582819218 0.698820798936253 0.88663582819218 0.88663582819218 0.88663582819218
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Aldh5a1 ENSMUSG00000035936 0.698856351817522 0.731292199827224 0.506993720611274 0.731292199827224 0.731292199827224 0.731292199827224
Syn1 ENSMUSG00000037217 0.755949027846733 0.820240065938674 0.567111127742349 0.820240065938674 0.820240065938674 0.820240065938674
Syn3 ENSMUSG00000059602 0.7812836618396 0.7812836618396 0.630828775334128 0.7812836618396 0.710244967230379 0.7812836618396
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gad1 ENSMUSG00000070880 0.768676916415066 0.936959438615519 0.936959438615519 0.936959438615519 0.829955651614648 0.936959438615519

Cilium Assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B9d1 ENSMUSG00000001039 0.261255851582578 0.707658185448372 0.695945776226171 0.707658185448372 0.707658185448372 0.707658185448372
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Bbs1 ENSMUSG00000006464 0.535252731043498 0.535252731043498 0.486936148072312 0.535252731043498 0.469722306572126 0.535252731043498
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Cep290 ENSMUSG00000019971 0.322990934704122 0.965374311164404 0.828150742216486 0.965374311164404 0.965374311164404 0.965374311164404
Nedd1 ENSMUSG00000019988 0.734229349862519 0.749166050307136 0.52226286622742 0.749166050307136 0.749166050307136 0.749166050307136
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Kif3c ENSMUSG00000020668 0.788276022035163 0.788276022035163 0.450227483881965 0.788276022035163 0.716455835633992 0.788276022035163
Pafah1b1 ENSMUSG00000020745 0.684268257790379 0.89324127106958 0.496924413629147 0.89324127106958 0.89324127106958 0.89324127106958
Fbf1 ENSMUSG00000020776 0.828124082443458 0.828124082443458 0.613280984684464 0.828124082443458 0.743174058793539 0.828124082443458
Exoc7 ENSMUSG00000020792 0.865240848199277 0.877677248195614 0.591264128545861 0.877677248195614 0.877677248195614 0.877677248195614
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Ttc8 ENSMUSG00000021013 0.719390438614795 0.921389481967084 0.921389481967084 0.921389481967084 0.607740786546488 0.921389481967084
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Arl6 ENSMUSG00000022722 0.566864459187481 0.949646031228839 0.949646031228839 0.949646031228839 0.883901627326227 0.949646031228839
Iqcb1 ENSMUSG00000022837 0.621632466185277 1 0.80974265031858 1 1 1
Tctn3 ENSMUSG00000025008 0.887018695168292 0.887018695168292 0.635675072560021 0.887018695168292 0.530058652358671 0.887018695168292
Arl3 ENSMUSG00000025035 0.758111755078801 0.97166325309163 0.641306791483619 0.97166325309163 0.97166325309163 0.97166325309163
Bbs4 ENSMUSG00000025235 0.809736044283554 0.874560766809878 0.436365037051699 0.874560766809878 0.874560766809878 0.874560766809878
Lztfl1 ENSMUSG00000025245 0.241493453021677 0.362240179532515 0.239981407729023 0.362240179532515 0.7581550549986 0.7581550549986
Kifap3 ENSMUSG00000026585 0.469704914413884 0.704557371620826 0.441087359212723 0.704557371620826 0.984255604899399 0.984255604899399
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Ift74 ENSMUSG00000028576 0.877627477162941 0.940209728595628 0.524816248895833 0.940209728595628 0.940209728595628 0.940209728595628
Kif17 ENSMUSG00000028758 0.477700574091495 0.968271571677874 0.69967043027693 0.968271571677874 0.968271571677874 0.968271571677874
Ift81 ENSMUSG00000029469 0.865233187490919 0.865233187490919 0.313361249759864 0.865233187490919 0.767201112193862 0.865233187490919
Exoc4 ENSMUSG00000029763 0.535214850816684 0.535214850816684 0.26293166955306 0.535214850816684 0.474542135548828 0.535214850816684
Ift122 ENSMUSG00000030323 0.34461691810264 0.496810180232696 0.132020445649969 0.396061336949908 0.496810180232696 0.496810180232696
Rho ENSMUSG00000030324 0.757266463676936 0.836801121052075 0.836801121052075 0.836801121052075 0.378777142477677 0.836801121052075
Mark4 ENSMUSG00000030397 0.630027780207552 0.800571449121301 0.800571449121301 0.800571449121301 0.496897799744606 0.800571449121301
Cnga4 ENSMUSG00000030897 0.186199731629399 0.279299597444098 0.466165544799658 0.466165544799658 0.101073112177992 0.279299597444098
Hdac6 ENSMUSG00000031161 0.399954411782688 0.704725705549976 0.604988890890964 0.704725705549976 0.704725705549976 0.704725705549976
Bbs2 ENSMUSG00000031755 0.743202922243233 0.743202922243233 0.690115844444411 0.743202922243233 0.512070547999815 0.743202922243233
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Rpgrip1l ENSMUSG00000033282 0.548339606086561 0.641316069471055 0.393342203841753 0.641316069471055 0.641316069471055 0.641316069471055
Ccp110 ENSMUSG00000033904 0.5245786184617 0.78686792769255 0.977959259486411 0.977959259486411 0.519411337281863 0.78686792769255
Exoc3 ENSMUSG00000034152 0.545689894474128 0.684283375866065 0.684283375866065 0.684283375866065 0.427067701967243 0.684283375866065
Bbs7 ENSMUSG00000037325 0.455256964026811 0.785352682969664 0.785352682969664 0.785352682969664 0.627220688152427 0.785352682969664
Wdr19 ENSMUSG00000037890 0.692981456679332 0.927653728659857 0.927653728659857 0.927653728659857 0.501892572248176 0.927653728659857
Ift172 ENSMUSG00000038564 0.556238495199306 0.556238495199306 0.215471960439658 0.556238495199306 0.496872914630153 0.556238495199306
Tctn1 ENSMUSG00000038593 0.393276997062887 0.457670953286746 0.438666364498551 0.457670953286746 0.457670953286746 0.457670953286746
Nphp4 ENSMUSG00000039577 0.825064672466261 0.984256086527084 0.902607337253489 0.984256086527084 0.984256086527084 0.984256086527084
Wdr34 ENSMUSG00000039715 0.145668443519464 0.273246675894099 0.221103675604603 0.273246675894099 0.273246675894099 0.273246675894099
Cc2d2a ENSMUSG00000039765 0.952793906901848 0.952793906901848 0.93080112172038 0.952793906901848 0.905744566880619 0.952793906901848
Azi1 ENSMUSG00000039781 0.148709747321024 0.354245996554195 0.236163997702796 0.354245996554195 0.965373082585772 0.965373082585772
Wdr60 ENSMUSG00000042050 0.971665836960465 0.971665836960465 0.887001362163679 0.971665836960465 0.831212587372261 0.971665836960465
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Dynlrb1 ENSMUSG00000047459 0.229007987094036 0.343511980641054 0.0464496219605353 0.139348865881606 0.752177062517396 0.752177062517396
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Ywhag ENSMUSG00000051391 0.561577446803949 0.842366170205924 0.0747261292216177 0.224178387664853 0.855885863447441 0.855885863447441
Ttc26 ENSMUSG00000056832 0.50186822425582 0.734236948547814 0.574842653666043 0.734236948547814 0.734236948547814 0.734236948547814
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Bbs5 ENSMUSG00000063145 0.644141326225708 0.927613096268093 0.899417726942463 0.927613096268093 0.927613096268093 0.927613096268093
Wdr35 ENSMUSG00000066643 0.921405510585521 0.921405510585521 0.883900082779099 0.921405510585521 0.572305780505373 0.921405510585521
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Ttbk2 ENSMUSG00000090100 0.173137721740185 0.519413165220555 0.940221332365923 0.971666026690415 0.971666026690415 0.971666026690415

Integration of energy metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd36 ENSMUSG00000002944 0.865229595152466 0.918271216079192 0.918271216079192 0.918271216079192 0.846635625757792 0.918271216079192
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Acaca ENSMUSG00000020532 0.965372286644278 0.965372286644278 0.406664215661721 0.965372286644278 0.678507277649498 0.965372286644278
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Adipoq ENSMUSG00000022878 0.148614600880852 0.256798700474195 0.649894220930573 0.649894220930573 0.171199133649463 0.256798700474195
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Adipor1 ENSMUSG00000026457 0.788368670010579 0.977960570821812 0.0721368433489326 0.216410530046798 0.977960570821812 0.977960570821812
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Acsl4 ENSMUSG00000031278 0.203923659236271 0.611770977708812 0.831219920926164 0.831219920926164 0.825072014238738 0.831219920926164
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Acsl3 ENSMUSG00000032883 0.238393789874622 0.715181369623866 0.740167267297243 0.740167267297243 0.615974694230415 0.740167267297243
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Opioid Signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Regulation of insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd36 ENSMUSG00000002944 0.865229595152466 0.918271216079192 0.918271216079192 0.918271216079192 0.846635625757792 0.918271216079192
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacna1d ENSMUSG00000015968 0.698195235612013 0.77271051992831 0.382451437466318 0.77271051992831 0.77271051992831 0.77271051992831
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Acsl4 ENSMUSG00000031278 0.203923659236271 0.611770977708812 0.831219920926164 0.831219920926164 0.825072014238738 0.831219920926164
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Acsl3 ENSMUSG00000032883 0.238393789874622 0.715181369623866 0.740167267297243 0.740167267297243 0.615974694230415 0.740167267297243
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

PLC beta mediated events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

DAG and IP3 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Serotonin Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Syn2 ENSMUSG00000009394 0.825050389878912 0.825050389878912 0.404423231124745 0.825050389878912 0.821990181966326 0.825050389878912
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Syn1 ENSMUSG00000037217 0.755949027846733 0.820240065938674 0.567111127742349 0.820240065938674 0.820240065938674 0.820240065938674
Syn3 ENSMUSG00000059602 0.7812836618396 0.7812836618396 0.630828775334128 0.7812836618396 0.710244967230379 0.7812836618396

GABA receptor activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Gabrb2 ENSMUSG00000007653 0.964229877269529 0.964229877269529 0.412632631205396 0.964229877269529 0.81799098779356 0.964229877269529
Gabra1 ENSMUSG00000010803 0.260241524254504 0.780724572763511 0.922251997145272 0.922251997145272 0.723018738107078 0.922251997145272
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Gabrg2 ENSMUSG00000020436 0.769736590676399 0.917621399583102 0.917621399583102 0.917621399583102 0.416674809884177 0.917621399583102
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gabra4 ENSMUSG00000029211 0.584766687185407 0.876210766071611 0.876210766071611 0.876210766071611 0.844569843598702 0.876210766071611
Gabra3 ENSMUSG00000031343 0.621416251591058 0.865159658778867 0.865159658778867 0.865159658778867 0.716406782171717 0.865159658778867
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Gabrb3 ENSMUSG00000033676 0.307958531399754 0.852500999510637 0.830837023582374 0.852500999510637 0.852500999510637 0.852500999510637
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gabrg3 ENSMUSG00000055026 0.745799954024 0.882707861339701 0.879372137990206 0.882707861339701 0.882707861339701 0.882707861339701
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Ca-dependent events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

LGI-ADAM interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Adam11 ENSMUSG00000020926 0.849725291498145 0.871448430410699 0.871448430410699 0.871448430410699 0.803614621262606 0.871448430410699
Adam23 ENSMUSG00000025964 0.564040841425451 0.946475498382026 0.877669307342194 0.946475498382026 0.946475498382026 0.946475498382026
Stx1b ENSMUSG00000030806 0.993700757445583 0.993700757445583 0.319038980252528 0.802654952668384 0.535103301778923 0.802654952668384
Lgi3 ENSMUSG00000033595 0.724531008901491 0.724531008901491 0.318173897815083 0.477260846722624 0.273456895018902 0.477260846722624
Lgi4 ENSMUSG00000036560 0.911945314188505 0.971665656713483 0.770031733298897 0.971665656713483 0.971665656713483 0.971665656713483
Lgi2 ENSMUSG00000039252 0.930394112174771 0.990487963644157 0.821377448848022 0.990487963644157 0.990487963644157 0.990487963644157
Adam22 ENSMUSG00000040537 0.481965862805922 0.912004500973267 0.912004500973267 0.912004500973267 0.803627747240467 0.912004500973267
Lgi1 ENSMUSG00000067242 0.721910189169288 0.722590961002967 0.722590961002967 0.722590961002967 0.71365542440453 0.722590961002967

CaM pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Calmodulin induced events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Hedgehog ‘off’ state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Ift122 ENSMUSG00000030323 0.34461691810264 0.496810180232696 0.132020445649969 0.396061336949908 0.496810180232696 0.496810180232696
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Rpgrip1l ENSMUSG00000033282 0.548339606086561 0.641316069471055 0.393342203841753 0.641316069471055 0.641316069471055 0.641316069471055
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Wdr19 ENSMUSG00000037890 0.692981456679332 0.927653728659857 0.927653728659857 0.927653728659857 0.501892572248176 0.927653728659857
Ift172 ENSMUSG00000038564 0.556238495199306 0.556238495199306 0.215471960439658 0.556238495199306 0.496872914630153 0.556238495199306
Gpr161 ENSMUSG00000040836 0.641351415541962 0.641351415541962 0.636094396515636 0.641351415541962 0.608594226374364 0.641351415541962
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Intu ENSMUSG00000060798 0.749180751164691 0.855939682133434 0.849748421378796 0.855939682133434 0.855939682133434 0.855939682133434
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Wdr35 ENSMUSG00000066643 0.921405510585521 0.921405510585521 0.883900082779099 0.921405510585521 0.572305780505373 0.921405510585521
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Intraflagellar transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Kif3c ENSMUSG00000020668 0.788276022035163 0.788276022035163 0.450227483881965 0.788276022035163 0.716455835633992 0.788276022035163
Kifap3 ENSMUSG00000026585 0.469704914413884 0.704557371620826 0.441087359212723 0.704557371620826 0.984255604899399 0.984255604899399
Ift74 ENSMUSG00000028576 0.877627477162941 0.940209728595628 0.524816248895833 0.940209728595628 0.940209728595628 0.940209728595628
Kif17 ENSMUSG00000028758 0.477700574091495 0.968271571677874 0.69967043027693 0.968271571677874 0.968271571677874 0.968271571677874
Ift81 ENSMUSG00000029469 0.865233187490919 0.865233187490919 0.313361249759864 0.865233187490919 0.767201112193862 0.865233187490919
Ift122 ENSMUSG00000030323 0.34461691810264 0.496810180232696 0.132020445649969 0.396061336949908 0.496810180232696 0.496810180232696
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Wdr19 ENSMUSG00000037890 0.692981456679332 0.927653728659857 0.927653728659857 0.927653728659857 0.501892572248176 0.927653728659857
Ift172 ENSMUSG00000038564 0.556238495199306 0.556238495199306 0.215471960439658 0.556238495199306 0.496872914630153 0.556238495199306
Wdr34 ENSMUSG00000039715 0.145668443519464 0.273246675894099 0.221103675604603 0.273246675894099 0.273246675894099 0.273246675894099
Wdr60 ENSMUSG00000042050 0.971665836960465 0.971665836960465 0.887001362163679 0.971665836960465 0.831212587372261 0.971665836960465
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Dynlrb1 ENSMUSG00000047459 0.229007987094036 0.343511980641054 0.0464496219605353 0.139348865881606 0.752177062517396 0.752177062517396
Ttc26 ENSMUSG00000056832 0.50186822425582 0.734236948547814 0.574842653666043 0.734236948547814 0.734236948547814 0.734236948547814
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Wdr35 ENSMUSG00000066643 0.921405510585521 0.921405510585521 0.883900082779099 0.921405510585521 0.572305780505373 0.921405510585521
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Fkbp1b ENSMUSG00000020635 0.67838623943518 0.94020814846731 0.734102818928033 0.94020814846731 0.94020814846731 0.94020814846731
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf12 ENSMUSG00000022523 0.735481651893555 0.939219949131427 0.939219949131427 0.939219949131427 0.862494288944481 0.939219949131427
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Kcnip2 ENSMUSG00000025221 0.865138946399732 0.865138946399732 0.535031755209987 0.865138946399732 0.803454707196558 0.865138946399732
Nppc ENSMUSG00000026241 0.609483026562215 0.93866457594603 0.785247476100659 0.93866457594603 0.93866457594603 0.93866457594603
Ahcyl1 ENSMUSG00000027893 0.803585201781793 0.977953489783539 0.977953489783539 0.977953489783539 0.737175540269971 0.977953489783539
Npr1 ENSMUSG00000027931 0.794482625931362 0.794482625931362 0.514580313547303 0.794482625931362 0.782304591029015 0.794482625931362
Tpm2 ENSMUSG00000028464 0.48901696268919 0.733525444033784 0.276643532403306 0.733525444033784 0.757962225810759 0.757962225810759
Npr2 ENSMUSG00000028469 0.44342049022645 0.665130735339675 0.23984106985107 0.665130735339675 0.902618376039097 0.902618376039097
Kcnip4 ENSMUSG00000029088 0.445077599944986 0.759159395757576 0.612008419684874 0.759159395757576 0.759159395757576 0.759159395757576
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Tmod2 ENSMUSG00000032186 0.157116988013436 0.471350964040307 0.550680905473204 0.734105078971322 0.734105078971322 0.734105078971322
Kcnk10 ENSMUSG00000033854 0.66478227229457 0.943076748487154 0.943076748487154 0.943076748487154 0.75383616685965 0.943076748487154
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fxyd7 ENSMUSG00000036578 0.429266975420368 0.6103666140928 0.342717167898781 0.6103666140928 0.6103666140928 0.6103666140928
Kcnk2 ENSMUSG00000037624 0.396773630912312 0.772836992914924 0.772836992914924 0.772836992914924 0.748490853924859 0.772836992914924
Myl6b ENSMUSG00000039824 0.993701282995693 0.993701282995693 0.20384838527018 0.611545155810539 0.831203284451507 0.993701282995693
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Itga1 ENSMUSG00000042284 0.346751688942525 0.604971298839042 0.604971298839042 0.604971298839042 0.46486447626571 0.604971298839042
Fgf11 ENSMUSG00000042826 0.585544643476472 0.955895923008687 0.821869550022072 0.955895923008687 0.955895923008687 0.955895923008687
Dmd ENSMUSG00000045103 0.225948699264408 0.526297800726904 0.350865200484603 0.526297800726904 0.527417081123953 0.527417081123953
Scn3b ENSMUSG00000049281 0.30654479948407 0.919634398452211 0.793926536833379 0.946452571395267 0.946452571395267 0.946452571395267
Kcnip1 ENSMUSG00000053519 0.790322545695729 0.824156296127533 0.799357591994899 0.824156296127533 0.824156296127533 0.824156296127533
Myh8 ENSMUSG00000055775 0.748871462341104 0.930636101919819 0.49066076679995 0.930636101919819 0.930636101919819 0.930636101919819
Scn3a ENSMUSG00000057182 0.549822880279604 0.742640594103942 0.686490207224732 0.742640594103942 0.742640594103942 0.742640594103942
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Scn1a ENSMUSG00000064329 0.228565863853541 0.685697591560622 0.554070895749723 0.744924725900363 0.744924725900363 0.744924725900363
Fxyd6 ENSMUSG00000066705 0.604968393504201 0.644142732695471 0.37816156867391 0.644142732695471 0.644142732695471 0.644142732695471
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Scn2b ENSMUSG00000070304 0.915003003694042 0.915003003694042 0.877642871861204 0.915003003694042 0.794197034769996 0.915003003694042
Scn2a1 ENSMUSG00000075318 0.19651465329244 0.58954395987732 0.919475212271158 0.919475212271158 0.878320961398532 0.919475212271158
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504
Kcnip3 ENSMUSG00000079056 0.959050310271809 0.959050310271809 0.615797298690923 0.959050310271809 0.930753732572343 0.959050310271809
Kcne1l ENSMUSG00000090122 0.943035949081477 0.987341532095268 0.920964728986533 0.987341532095268 0.987341532095268 0.987341532095268

Glutamate binding, activation of AMPA receptors and synaptic plasticity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Akap5 ENSMUSG00000021057 0.607590203677987 0.958974394225523 0.861726528780859 0.958974394225523 0.958974394225523 0.958974394225523
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Trafficking of AMPA receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Akap5 ENSMUSG00000021057 0.607590203677987 0.958974394225523 0.861726528780859 0.958974394225523 0.958974394225523 0.958974394225523
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Semaphorin interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Trem2 ENSMUSG00000023992 0.675571492686183 0.871308680119938 0.871308680119938 0.871308680119938 0.454725265732204 0.871308680119938
Dpysl3 ENSMUSG00000024501 0.455246018180067 0.803607788697596 0.803607788697596 0.803607788697596 0.661217288805153 0.803607788697596
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Crmp1 ENSMUSG00000029121 0.974780940800692 0.974780940800692 0.703852424803108 0.974780940800692 0.716019435270133 0.974780940800692
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Plxnb3 ENSMUSG00000031385 0.858919312754963 0.858919312754963 0.311087152421553 0.661320759556636 0.44088050637109 0.661320759556636
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rhob ENSMUSG00000054364 0.627229077552181 0.927675553302141 0.104015613170298 0.312046839510893 0.927675553302141 0.927675553302141
Rnd1 ENSMUSG00000054855 0.661203233113187 0.661203233113187 0.298379466146235 0.661203233113187 0.627172996382542 0.661203233113187
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Sema3e ENSMUSG00000063531 0.667952496734551 0.700802645980391 0.700802645980391 0.700802645980391 0.583640050957042 0.700802645980391

PKA activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

CRMPs in Sema3A signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Dpysl3 ENSMUSG00000024501 0.455246018180067 0.803607788697596 0.803607788697596 0.803607788697596 0.661217288805153 0.803607788697596
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Crmp1 ENSMUSG00000029121 0.974780940800692 0.974780940800692 0.703852424803108 0.974780940800692 0.716019435270133 0.974780940800692
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821

PKA-mediated phosphorylation of CREB

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

Organelle biogenesis and maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B9d1 ENSMUSG00000001039 0.261255851582578 0.707658185448372 0.695945776226171 0.707658185448372 0.707658185448372 0.707658185448372
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Bbs1 ENSMUSG00000006464 0.535252731043498 0.535252731043498 0.486936148072312 0.535252731043498 0.469722306572126 0.535252731043498
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Cep290 ENSMUSG00000019971 0.322990934704122 0.965374311164404 0.828150742216486 0.965374311164404 0.965374311164404 0.965374311164404
Nedd1 ENSMUSG00000019988 0.734229349862519 0.749166050307136 0.52226286622742 0.749166050307136 0.749166050307136 0.749166050307136
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Kif3c ENSMUSG00000020668 0.788276022035163 0.788276022035163 0.450227483881965 0.788276022035163 0.716455835633992 0.788276022035163
Pafah1b1 ENSMUSG00000020745 0.684268257790379 0.89324127106958 0.496924413629147 0.89324127106958 0.89324127106958 0.89324127106958
Fbf1 ENSMUSG00000020776 0.828124082443458 0.828124082443458 0.613280984684464 0.828124082443458 0.743174058793539 0.828124082443458
Exoc7 ENSMUSG00000020792 0.865240848199277 0.877677248195614 0.591264128545861 0.877677248195614 0.877677248195614 0.877677248195614
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Ttc8 ENSMUSG00000021013 0.719390438614795 0.921389481967084 0.921389481967084 0.921389481967084 0.607740786546488 0.921389481967084
Csnk1e ENSMUSG00000022433 0.930802663453991 0.930802663453991 0.862115750244554 0.930802663453991 0.918267796798224 0.930802663453991
Arl6 ENSMUSG00000022722 0.566864459187481 0.949646031228839 0.949646031228839 0.949646031228839 0.883901627326227 0.949646031228839
Iqcb1 ENSMUSG00000022837 0.621632466185277 1 0.80974265031858 1 1 1
Tctn3 ENSMUSG00000025008 0.887018695168292 0.887018695168292 0.635675072560021 0.887018695168292 0.530058652358671 0.887018695168292
Arl3 ENSMUSG00000025035 0.758111755078801 0.97166325309163 0.641306791483619 0.97166325309163 0.97166325309163 0.97166325309163
Bbs4 ENSMUSG00000025235 0.809736044283554 0.874560766809878 0.436365037051699 0.874560766809878 0.874560766809878 0.874560766809878
Lztfl1 ENSMUSG00000025245 0.241493453021677 0.362240179532515 0.239981407729023 0.362240179532515 0.7581550549986 0.7581550549986
Kifap3 ENSMUSG00000026585 0.469704914413884 0.704557371620826 0.441087359212723 0.704557371620826 0.984255604899399 0.984255604899399
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Ift74 ENSMUSG00000028576 0.877627477162941 0.940209728595628 0.524816248895833 0.940209728595628 0.940209728595628 0.940209728595628
Kif17 ENSMUSG00000028758 0.477700574091495 0.968271571677874 0.69967043027693 0.968271571677874 0.968271571677874 0.968271571677874
Ift81 ENSMUSG00000029469 0.865233187490919 0.865233187490919 0.313361249759864 0.865233187490919 0.767201112193862 0.865233187490919
Sirt4 ENSMUSG00000029524 0.338770774625337 0.529409418234497 0.352939612156331 0.529409418234497 0.550964897197138 0.550964897197138
Exoc4 ENSMUSG00000029763 0.535214850816684 0.535214850816684 0.26293166955306 0.535214850816684 0.474542135548828 0.535214850816684
Ift122 ENSMUSG00000030323 0.34461691810264 0.496810180232696 0.132020445649969 0.396061336949908 0.496810180232696 0.496810180232696
Rho ENSMUSG00000030324 0.757266463676936 0.836801121052075 0.836801121052075 0.836801121052075 0.378777142477677 0.836801121052075
Mark4 ENSMUSG00000030397 0.630027780207552 0.800571449121301 0.800571449121301 0.800571449121301 0.496897799744606 0.800571449121301
Cnga4 ENSMUSG00000030897 0.186199731629399 0.279299597444098 0.466165544799658 0.466165544799658 0.101073112177992 0.279299597444098
Hdac6 ENSMUSG00000031161 0.399954411782688 0.704725705549976 0.604988890890964 0.704725705549976 0.704725705549976 0.704725705549976
Bbs2 ENSMUSG00000031755 0.743202922243233 0.743202922243233 0.690115844444411 0.743202922243233 0.512070547999815 0.743202922243233
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Rpgrip1l ENSMUSG00000033282 0.548339606086561 0.641316069471055 0.393342203841753 0.641316069471055 0.641316069471055 0.641316069471055
Ccp110 ENSMUSG00000033904 0.5245786184617 0.78686792769255 0.977959259486411 0.977959259486411 0.519411337281863 0.78686792769255
Exoc3 ENSMUSG00000034152 0.545689894474128 0.684283375866065 0.684283375866065 0.684283375866065 0.427067701967243 0.684283375866065
Bbs7 ENSMUSG00000037325 0.455256964026811 0.785352682969664 0.785352682969664 0.785352682969664 0.627220688152427 0.785352682969664
Wdr19 ENSMUSG00000037890 0.692981456679332 0.927653728659857 0.927653728659857 0.927653728659857 0.501892572248176 0.927653728659857
Ift172 ENSMUSG00000038564 0.556238495199306 0.556238495199306 0.215471960439658 0.556238495199306 0.496872914630153 0.556238495199306
Tctn1 ENSMUSG00000038593 0.393276997062887 0.457670953286746 0.438666364498551 0.457670953286746 0.457670953286746 0.457670953286746
Nphp4 ENSMUSG00000039577 0.825064672466261 0.984256086527084 0.902607337253489 0.984256086527084 0.984256086527084 0.984256086527084
Wdr34 ENSMUSG00000039715 0.145668443519464 0.273246675894099 0.221103675604603 0.273246675894099 0.273246675894099 0.273246675894099
Cc2d2a ENSMUSG00000039765 0.952793906901848 0.952793906901848 0.93080112172038 0.952793906901848 0.905744566880619 0.952793906901848
Azi1 ENSMUSG00000039781 0.148709747321024 0.354245996554195 0.236163997702796 0.354245996554195 0.965373082585772 0.965373082585772
Wdr60 ENSMUSG00000042050 0.971665836960465 0.971665836960465 0.887001362163679 0.971665836960465 0.831212587372261 0.971665836960465
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Dynlrb1 ENSMUSG00000047459 0.229007987094036 0.343511980641054 0.0464496219605353 0.139348865881606 0.752177062517396 0.752177062517396
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Ywhag ENSMUSG00000051391 0.561577446803949 0.842366170205924 0.0747261292216177 0.224178387664853 0.855885863447441 0.855885863447441
Ttc26 ENSMUSG00000056832 0.50186822425582 0.734236948547814 0.574842653666043 0.734236948547814 0.734236948547814 0.734236948547814
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Bbs5 ENSMUSG00000063145 0.644141326225708 0.927613096268093 0.899417726942463 0.927613096268093 0.927613096268093 0.927613096268093
Wdr35 ENSMUSG00000066643 0.921405510585521 0.921405510585521 0.883900082779099 0.921405510585521 0.572305780505373 0.921405510585521
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Ttbk2 ENSMUSG00000090100 0.173137721740185 0.519413165220555 0.940221332365923 0.971666026690415 0.971666026690415 0.971666026690415

Phase 1 - inactivation of fast Na+ channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnd1 ENSMUSG00000009731 0.527439984977603 0.739927711496245 0.739927711496245 0.739927711496245 0.558449076414853 0.739927711496245
Kcnip2 ENSMUSG00000025221 0.865138946399732 0.865138946399732 0.535031755209987 0.865138946399732 0.803454707196558 0.865138946399732
Kcnip4 ENSMUSG00000029088 0.445077599944986 0.759159395757576 0.612008419684874 0.759159395757576 0.759159395757576 0.759159395757576
Kcnd3 ENSMUSG00000040896 0.330691794861936 0.874559099931214 0.658293435914599 0.874559099931214 0.874559099931214 0.874559099931214
Kcnip1 ENSMUSG00000053519 0.790322545695729 0.824156296127533 0.799357591994899 0.824156296127533 0.824156296127533 0.824156296127533
Kcnd2 ENSMUSG00000060882 0.286492494986926 0.859477484960779 0.919443802818695 0.919443802818695 0.622271915054065 0.919443802818695
Kcnip3 ENSMUSG00000079056 0.959050310271809 0.959050310271809 0.615797298690923 0.959050310271809 0.930753732572343 0.959050310271809

Ionotropic activity of kainate receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585

Activation of Ca-permeable Kainate Receptor

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585

Glutamate Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965

Signaling by Hedgehog

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Shh ENSMUSG00000002633 0.876704104528828 0.918642105139929 0.53294927851716 0.918642105139929 0.918642105139929 0.918642105139929
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Kif3a ENSMUSG00000018395 0.122178376177734 0.366535128533201 0.479417010069732 0.719125515104599 0.896321330059506 0.896321330059506
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Gli3 ENSMUSG00000021318 0.596530109424275 0.894795164136412 0.943304352212042 0.943304352212042 0.429158280978761 0.894795164136412
Ptch1 ENSMUSG00000021466 0.893249756068309 0.977959281630978 0.880789524710316 0.977959281630978 0.977959281630978 0.977959281630978
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gli1 ENSMUSG00000025407 0.556163691041603 0.868160330133478 0.704304648007419 0.868160330133478 0.868160330133478 0.868160330133478
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Ift122 ENSMUSG00000030323 0.34461691810264 0.496810180232696 0.132020445649969 0.396061336949908 0.496810180232696 0.496810180232696
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Ift57 ENSMUSG00000032965 0.761153126814666 0.908859350275476 0.89949026705953 0.908859350275476 0.908859350275476 0.908859350275476
Rpgrip1l ENSMUSG00000033282 0.548339606086561 0.641316069471055 0.393342203841753 0.641316069471055 0.641316069471055 0.641316069471055
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Wdr19 ENSMUSG00000037890 0.692981456679332 0.927653728659857 0.927653728659857 0.927653728659857 0.501892572248176 0.927653728659857
Ift172 ENSMUSG00000038564 0.556238495199306 0.556238495199306 0.215471960439658 0.556238495199306 0.496872914630153 0.556238495199306
Disp2 ENSMUSG00000040035 0.974725405316524 0.974725405316524 0.598350781940388 0.974725405316524 0.76375930239046 0.974725405316524
Gas8 ENSMUSG00000040220 0.588480499302243 0.695886932218957 0.39329479720181 0.695886932218957 0.695886932218957 0.695886932218957
Gpr161 ENSMUSG00000040836 0.641351415541962 0.641351415541962 0.636094396515636 0.641351415541962 0.608594226374364 0.641351415541962
Dzip1 ENSMUSG00000042156 0.92137411783994 0.92137411783994 0.794463957122198 0.92137411783994 0.905730420405554 0.92137411783994
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Dync2h1 ENSMUSG00000047193 0.354965488986888 0.915118698696999 0.915118698696999 0.915118698696999 0.692908104911487 0.915118698696999
Gli2 ENSMUSG00000048402 0.743080289265356 0.767073522862929 0.527329776069606 0.767073522862929 0.767073522862929 0.767073522862929
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Intu ENSMUSG00000060798 0.749180751164691 0.855939682133434 0.849748421378796 0.855939682133434 0.855939682133434 0.855939682133434
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Wdr35 ENSMUSG00000066643 0.921405510585521 0.921405510585521 0.883900082779099 0.921405510585521 0.572305780505373 0.921405510585521
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

G alpha (z) signalling events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rgs20 ENSMUSG00000002459 0.820894723890242 0.820894723890242 0.79346414606527 0.820894723890242 0.716078565490359 0.820894723890242
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Rgs17 ENSMUSG00000019775 0.44498415891806 0.927455121576114 0.625935665673364 0.927455121576114 0.927455121576114 0.927455121576114
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Phase 0 - rapid depolarisation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf12 ENSMUSG00000022523 0.735481651893555 0.939219949131427 0.939219949131427 0.939219949131427 0.862494288944481 0.939219949131427
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fgf11 ENSMUSG00000042826 0.585544643476472 0.955895923008687 0.821869550022072 0.955895923008687 0.955895923008687 0.955895923008687
Scn3b ENSMUSG00000049281 0.30654479948407 0.919634398452211 0.793926536833379 0.946452571395267 0.946452571395267 0.946452571395267
Scn3a ENSMUSG00000057182 0.549822880279604 0.742640594103942 0.686490207224732 0.742640594103942 0.742640594103942 0.742640594103942
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686
Scn1a ENSMUSG00000064329 0.228565863853541 0.685697591560622 0.554070895749723 0.744924725900363 0.744924725900363 0.744924725900363
Cacng7 ENSMUSG00000069806 0.746052124013458 0.949620764041663 0.949620764041663 0.949620764041663 0.871404865227394 0.949620764041663
Scn2b ENSMUSG00000070304 0.915003003694042 0.915003003694042 0.877642871861204 0.915003003694042 0.794197034769996 0.915003003694042
Scn2a1 ENSMUSG00000075318 0.19651465329244 0.58954395987732 0.919475212271158 0.919475212271158 0.878320961398532 0.919475212271158

Activation of kainate receptors upon glutamate binding

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grik3 ENSMUSG00000001985 0.565883508425584 0.854231743144912 0.854231743144912 0.854231743144912 0.838104992577763 0.854231743144912
Grik5 ENSMUSG00000003378 0.479361089222175 0.629826532450184 0.629826532450184 0.629826532450184 0.427066305002614 0.629826532450184
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Grik4 ENSMUSG00000032017 0.705432421981138 0.957808524533058 0.957808524533058 0.957808524533058 0.873861683329916 0.957808524533058
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Ncald ENSMUSG00000051359 0.815854838800241 0.815854838800241 0.791418962394157 0.815854838800241 0.652667286544825 0.815854838800241
Grik2 ENSMUSG00000056073 0.5289159553429 0.529996656698585 0.427297939074594 0.529996656698585 0.529996656698585 0.529996656698585
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Acetylcholine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953

Activation of GABAB receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

GABA B receptor activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Presynaptic depolarization and calcium channel opening

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.812807697131856 0.940227627965701 0.604965488105476 0.940227627965701 0.940227627965701 0.940227627965701
Cacna1b ENSMUSG00000004113 0.489875583637996 0.936604085758047 0.756556741528913 0.936604085758047 0.936604085758047 0.936604085758047
Cacna2d2 ENSMUSG00000010066 0.871423108198033 0.883452619255449 0.883452619255449 0.883452619255449 0.648694312190509 0.883452619255449
Cacnb4 ENSMUSG00000017412 0.597081950108302 0.86431676846104 0.404331377090103 0.86431676846104 0.86431676846104 0.86431676846104
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Cacna2d3 ENSMUSG00000021991 0.676864129294639 0.981008993487423 0.971633679668821 0.981008993487423 0.981008993487423 0.981008993487423
Cacna1a ENSMUSG00000034656 0.788363177336611 0.788363177336611 0.788337485332054 0.788363177336611 0.596662817652596 0.788363177336611
Cacnb2 ENSMUSG00000057914 0.684141988924666 0.937067865335686 0.532472008655162 0.937067865335686 0.937067865335686 0.937067865335686

Receptor-type tyrosine-protein phosphatases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Ptprs ENSMUSG00000013236 0.943368755766956 0.943368755766956 0.684301361214679 0.943368755766956 0.794480068246185 0.943368755766956
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Ptprd ENSMUSG00000028399 0.459966705443304 0.689950058164955 0.393236199340387 0.689950058164955 0.990549881514966 0.990549881514966
Slitrk5 ENSMUSG00000033214 0.954301730371711 0.954301730371711 0.696543180488229 0.954301730371711 0.810175314718082 0.954301730371711
Slitrk2 ENSMUSG00000036790 0.707265538443087 0.936303643579166 0.828874618019525 0.936303643579166 0.936303643579166 0.936303643579166
Slitrk4 ENSMUSG00000046699 0.453461673413167 0.954643989995591 0.954643989995591 0.954643989995591 0.927969965345874 0.954643989995591
Lrrc4b ENSMUSG00000047085 0.580727279922867 0.939134465864034 0.939134465864034 0.939134465864034 0.760107131568757 0.939134465864034
Slitrk3 ENSMUSG00000048304 0.614670646547173 0.993391837135839 0.782152084098795 0.993391837135839 0.993391837135839 0.993391837135839
Ntrk3 ENSMUSG00000059146 0.899407856512363 0.899407856512363 0.695722258925379 0.899407856512363 0.657950245869533 0.899407856512363
Slitrk1 ENSMUSG00000075478 0.693232378264004 0.780170177965392 0.669321443154951 0.780170177965392 0.780170177965392 0.780170177965392

Platelet homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Pde10a ENSMUSG00000023868 0.41714785599035 0.764255216098399 0.962160233881058 0.962160233881058 0.509503477398933 0.764255216098399
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
P2rx3 ENSMUSG00000027071 0.457675632452868 0.457675632452868 0.427068943705184 0.457675632452868 0.361213091154555 0.457675632452868
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Lrp8 ENSMUSG00000028613 0.974744804383567 0.974744804383567 0.959022400634642 0.974744804383567 0.833947892490056 0.974744804383567
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Pde2a ENSMUSG00000030653 0.669851483713912 0.669851483713912 0.236824406494783 0.669851483713912 0.655518548162739 0.669851483713912
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Pde11a ENSMUSG00000075270 0.54212265120549 0.886803769999323 0.740010141364011 0.886803769999323 0.886803769999323 0.886803769999323
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

GABA synthesis, release, reuptake and degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Gad2 ENSMUSG00000026787 0.62440231835418 0.88663582819218 0.698820798936253 0.88663582819218 0.88663582819218 0.88663582819218
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953
Aldh5a1 ENSMUSG00000035936 0.698856351817522 0.731292199827224 0.506993720611274 0.731292199827224 0.731292199827224 0.731292199827224
Gad1 ENSMUSG00000070880 0.768676916415066 0.936959438615519 0.936959438615519 0.936959438615519 0.829955651614648 0.936959438615519

G alpha (12/13) signalling events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Arhgef40 ENSMUSG00000004562 0.690115975723052 0.734258969628961 0.734258969628961 0.734258969628961 0.344799955228746 0.734258969628961
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Tiam2 ENSMUSG00000023800 0.862097039059075 0.862097039059075 0.644127593764966 0.862097039059075 0.687109235269195 0.862097039059075
Fgd1 ENSMUSG00000025265 0.618850897072831 0.943366293933116 0.806686983694517 0.943366293933116 0.943366293933116 0.943366293933116
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Arhgef17 ENSMUSG00000032875 0.902626804113539 0.91513128746116 0.722365064561738 0.91513128746116 0.91513128746116 0.91513128746116
Arhgef26 ENSMUSG00000036885 0.338744587725774 0.624404520746658 0.624404520746658 0.624404520746658 0.556253327919585 0.624404520746658
Plekhg5 ENSMUSG00000039713 0.779235921324691 0.779235921324691 0.749170734286215 0.779235921324691 0.519662892686707 0.779235921324691
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Arhgef15 ENSMUSG00000052921 0.678504395758495 0.678504395758495 0.397719918405541 0.678504395758495 0.545704084312357 0.678504395758495
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rhob ENSMUSG00000054364 0.627229077552181 0.927675553302141 0.104015613170298 0.312046839510893 0.927675553302141 0.927675553302141
Arhgef33 ENSMUSG00000054901 0.724651036641199 0.951403625820301 0.951403625820301 0.951403625820301 0.762641987834789 0.951403625820301
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Arhgef10 ENSMUSG00000071176 0.828121266477381 0.828121266477381 0.558870934116684 0.828121266477381 0.357078975694619 0.828121266477381
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Ion homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Fkbp1b ENSMUSG00000020635 0.67838623943518 0.94020814846731 0.734102818928033 0.94020814846731 0.94020814846731 0.94020814846731
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ahcyl1 ENSMUSG00000027893 0.803585201781793 0.977953489783539 0.977953489783539 0.977953489783539 0.737175540269971 0.977953489783539
Nos1 ENSMUSG00000029361 0.927456763084531 0.927456763084531 0.867962663214752 0.927456763084531 0.751815040445157 0.927456763084531
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fxyd7 ENSMUSG00000036578 0.429266975420368 0.6103666140928 0.342717167898781 0.6103666140928 0.6103666140928 0.6103666140928
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fxyd6 ENSMUSG00000066705 0.604968393504201 0.644142732695471 0.37816156867391 0.644142732695471 0.644142732695471 0.644142732695471
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Developmental Biology

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh4 ENSMUSG00000000305 0.883898435194215 0.962222928866681 0.962222928866681 0.962222928866681 0.499291839744365 0.962222928866681
Itga5 ENSMUSG00000000555 0.367487527174105 0.551231290761157 0.105681181954657 0.317043545863971 0.675545918638298 0.675545918638298
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Akt3 ENSMUSG00000019699 0.450451599134282 0.749018331939007 0.943367108267536 0.943367108267536 0.499345554626005 0.749018331939007
Grb10 ENSMUSG00000020176 0.862131756215552 0.862131756215552 0.326849349555167 0.862131756215552 0.725321363060051 0.862131756215552
Cacng4 ENSMUSG00000020723 1 1 0.529151781776771 1 0.809126183612991 1
Spag9 ENSMUSG00000020859 0.315256214431106 0.945768643293318 0.655470152715938 0.959084152036622 0.959084152036622 0.959084152036622
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Adam11 ENSMUSG00000020926 0.849725291498145 0.871448430410699 0.871448430410699 0.871448430410699 0.803614621262606 0.871448430410699
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Dpysl2 ENSMUSG00000022048 0.728319474272986 0.800578185439495 0.29106165733565 0.800578185439495 0.800578185439495 0.800578185439495
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Shank3 ENSMUSG00000022623 0.367462953030198 0.788390175022533 0.664087446213001 0.788390175022533 0.788390175022533 0.788390175022533
Gsk3b ENSMUSG00000022812 0.572302603257234 0.940228107548902 0.701793966576461 0.940228107548902 0.940228107548902 0.940228107548902
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Enah ENSMUSG00000022995 0.545694923934996 0.984256859851334 0.837393509931509 0.984256859851334 0.984256859851334 0.984256859851334
Trem2 ENSMUSG00000023992 0.675571492686183 0.871308680119938 0.871308680119938 0.871308680119938 0.454725265732204 0.871308680119938
Cdh2 ENSMUSG00000024304 0.899500180223969 0.899500180223969 0.548331065648196 0.899500180223969 0.695924443971456 0.899500180223969
Dpysl3 ENSMUSG00000024501 0.455246018180067 0.803607788697596 0.803607788697596 0.803607788697596 0.661217288805153 0.803607788697596
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
St8sia2 ENSMUSG00000025789 0.424675931893258 0.74496319565452 0.66720559161028 0.74496319565452 0.74496319565452 0.74496319565452
Itgb1 ENSMUSG00000025809 0.436380179692487 0.719443783279685 0.713537010461171 0.719443783279685 0.719443783279685 0.719443783279685
Unc5a ENSMUSG00000025876 0.812552222144865 0.812552222144865 0.767074155135085 0.812552222144865 0.704363534681499 0.812552222144865
Adam23 ENSMUSG00000025964 0.564040841425451 0.946475498382026 0.877669307342194 0.946475498382026 0.946475498382026 0.946475498382026
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Nfasc ENSMUSG00000026442 0.698355335532337 0.698355335532337 0.646491985253954 0.698355335532337 0.660344021623246 0.698355335532337
Plxna2 ENSMUSG00000026640 0.298316478830715 0.894949436492146 0.990553736263164 0.990553736263164 0.755174694885028 0.990553736263164
Dnm1 ENSMUSG00000026825 0.635654987616952 0.704718381483473 0.701787179736661 0.704718381483473 0.704718381483473 0.704718381483473
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Pkp4 ENSMUSG00000026991 0.990550393572276 0.990550393572276 0.695912533394215 0.990550393572276 0.987400832322106 0.990550393572276
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Dok5 ENSMUSG00000027560 0.752557960971498 0.752557960971498 0.735789387224965 0.752557960971498 0.655254834944887 0.752557960971498
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Pfn2 ENSMUSG00000027805 0.779261699129771 0.996850638156217 0.996850638156217 0.996850638156217 0.806684761982432 0.996850638156217
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Sh3gl2 ENSMUSG00000028488 0.968519675120957 0.968519675120957 0.831222278599938 0.968519675120957 0.815862937084519 0.968519675120957
Dab1 ENSMUSG00000028519 0.911931053123151 0.911931053123151 0.666573021804146 0.911931053123151 0.643795719176379 0.911931053123151
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Crmp1 ENSMUSG00000029121 0.974780940800692 0.974780940800692 0.703852424803108 0.974780940800692 0.716019435270133 0.974780940800692
Dpysl5 ENSMUSG00000029168 0.511848792421275 0.993695898854621 0.993695898854621 0.993695898854621 0.745890192678754 0.993695898854621
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Limk1 ENSMUSG00000029674 0.896345301852602 0.896345301852602 0.85279447747278 0.896345301852602 0.467300737211333 0.896345301852602
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Plxna4 ENSMUSG00000029765 0.738163403495216 0.738163403495216 0.338828244766529 0.738163403495216 0.694420014081244 0.738163403495216
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Plxna1 ENSMUSG00000030084 0.924537913123972 0.924537913123972 0.467227590211281 0.924537913123972 0.649773269493267 0.924537913123972
Mef2a ENSMUSG00000030557 0.321019140520577 0.826436592338726 0.550957728225818 0.826436592338726 0.880780078245997 0.880780078245997
Stx1b ENSMUSG00000030806 0.993700757445583 0.993700757445583 0.319038980252528 0.802654952668384 0.535103301778923 0.802654952668384
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Plxnb3 ENSMUSG00000031385 0.858919312754963 0.858919312754963 0.311087152421553 0.661320759556636 0.44088050637109 0.661320759556636
Plxna3 ENSMUSG00000031398 0.865192760842934 0.865192760842934 0.35685695109363 0.535285426640445 0.280138151560146 0.535285426640445
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Slit2 ENSMUSG00000031558 0.687185789711974 0.930806648357942 0.930806648357942 0.930806648357942 0.890126121650186 0.930806648357942
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Dscaml1 ENSMUSG00000032087 0.743624103954924 0.879546593432192 0.879546593432192 0.879546593432192 0.755383506167265 0.879546593432192
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Lgi3 ENSMUSG00000033595 0.724531008901491 0.724531008901491 0.318173897815083 0.477260846722624 0.273456895018902 0.477260846722624
Lgi4 ENSMUSG00000036560 0.911945314188505 0.971665656713483 0.770031733298897 0.971665656713483 0.971665656713483 0.971665656713483
Rras ENSMUSG00000038387 0.203658396253892 0.305487594380838 0.152722300858945 0.305487594380838 0.313283858925241 0.313283858925241
Lgi2 ENSMUSG00000039252 0.930394112174771 0.990487963644157 0.821377448848022 0.990487963644157 0.990487963644157 0.990487963644157
Dnm3 ENSMUSG00000040265 0.728256910525605 0.924484698459049 0.924484698459049 0.924484698459049 0.438522845168936 0.924484698459049
Adam22 ENSMUSG00000040537 0.481965862805922 0.912004500973267 0.912004500973267 0.912004500973267 0.803627747240467 0.912004500973267
Rap1gap ENSMUSG00000041351 0.874516196622842 0.883872708327981 0.78529204277281 0.883872708327981 0.883872708327981 0.883872708327981
Reln ENSMUSG00000042453 0.84973980073636 0.868339138601379 0.336766536613965 0.868339138601379 0.868339138601379 0.868339138601379
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Krt1 ENSMUSG00000046834 0.429580217022001 0.529634567310004 0.529634567310004 0.529634567310004 0.508496614849032 0.529634567310004
Gap43 ENSMUSG00000047261 0.993653299594886 0.993653299594886 0.765673954326294 0.993653299594886 0.965217607319514 0.993653299594886
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Cdk5r1 ENSMUSG00000048895 0.764109168764821 0.764109168764821 0.252476217551533 0.757428652654599 0.545300371143079 0.764109168764821
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Dscam ENSMUSG00000050272 0.951102378539934 0.951102378539934 0.869577730490515 0.951102378539934 0.654053762644395 0.951102378539934
Cntn2 ENSMUSG00000053024 0.946920054315675 0.946920054315675 0.718580352683058 0.946920054315675 0.560606666115818 0.946920054315675
Tcf4 ENSMUSG00000053477 0.681394815474966 0.974813502210302 0.974813502210302 0.974813502210302 0.74021804123123 0.974813502210302
Plxnb1 ENSMUSG00000053646 0.3307150454467 0.773233553074474 0.6300033019728 0.773233553074474 0.773233553074474 0.773233553074474
Rhob ENSMUSG00000054364 0.627229077552181 0.927675553302141 0.104015613170298 0.312046839510893 0.927675553302141 0.927675553302141
Rnd1 ENSMUSG00000054855 0.661203233113187 0.661203233113187 0.298379466146235 0.661203233113187 0.627172996382542 0.661203233113187
Slit3 ENSMUSG00000056427 0.89318101208312 0.918220401047043 0.704618619398227 0.918220401047043 0.918220401047043 0.918220401047043
Grlf1 ENSMUSG00000058230 0.704687633324159 0.849750045872185 0.417898997350992 0.849750045872185 0.849750045872185 0.849750045872185
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Ctnna2 ENSMUSG00000063063 0.852580870048482 0.946358571486801 0.754645104338889 0.946358571486801 0.946358571486801 0.946358571486801
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sema3e ENSMUSG00000063531 0.667952496734551 0.700802645980391 0.700802645980391 0.700802645980391 0.583640050957042 0.700802645980391
Lgi1 ENSMUSG00000067242 0.721910189169288 0.722590961002967 0.722590961002967 0.722590961002967 0.71365542440453 0.722590961002967
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

G alpha (i) signalling events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rgs20 ENSMUSG00000002459 0.820894723890242 0.820894723890242 0.79346414606527 0.820894723890242 0.716078565490359 0.820894723890242
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Ccl6 ENSMUSG00000018927 0.971654522167911 0.971654522167911 0.78821263178141 0.971654522167911 0.87446006544789 0.971654522167911
Ccl9 ENSMUSG00000019122 0.868342576542606 0.868342576542606 0.638411734452223 0.868342576542606 0.755133023615109 0.868342576542606
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Rgs17 ENSMUSG00000019775 0.44498415891806 0.927455121576114 0.625935665673364 0.927455121576114 0.927455121576114 0.927455121576114
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Rgs9 ENSMUSG00000020599 0.892885470078516 0.892885470078516 0.842658173856563 0.892885470078516 0.787592383736084 0.892885470078516
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Rgs6 ENSMUSG00000021219 0.833942735183491 0.933797572547903 0.933797572547903 0.933797572547903 0.927500409058025 0.933797572547903
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Lrp12 ENSMUSG00000022305 0.862119287281727 0.946509747247406 0.946509747247406 0.946509747247406 0.417927916952119 0.946509747247406
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Gpihbp1 ENSMUSG00000022579 0.791033639942828 0.791033639942828 0.781968601666039 0.791033639942828 0.518860917248302 0.791033639942828
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
C3 ENSMUSG00000024164 0.675614763347999 0.97166728513593 0.97166728513593 0.97166728513593 0.893257765188331 0.97166728513593
Grm8 ENSMUSG00000024211 0.581459279843197 0.863797416908078 0.863797416908078 0.863797416908078 0.746413291246183 0.863797416908078
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gpr37l1 ENSMUSG00000026424 0.803430731628327 0.852391434517777 0.430344704615273 0.852391434517777 0.852391434517777 0.852391434517777
Opn3 ENSMUSG00000026525 0.7882032871944 0.996845708704885 0.430664212814841 0.996845708704885 0.996845708704885 0.996845708704885
Rgs7 ENSMUSG00000026527 0.65389164613042 0.796516757956675 0.377205322571775 0.796516757956675 0.796516757956675 0.796516757956675
Nmt2 ENSMUSG00000026643 0.707612288010767 0.880767668918136 0.755165721738714 0.880767668918136 0.880767668918136 0.880767668918136
Gpsm1 ENSMUSG00000026930 0.716461018413858 0.883894612012206 0.883894612012206 0.883894612012206 0.761180673630404 0.883894612012206
Oprl1 ENSMUSG00000027584 0.933329245678453 0.936720060465393 0.936720060465393 0.936720060465393 0.471739845590983 0.936720060465393
Abca4 ENSMUSG00000028125 0.317815787275002 0.874266061128759 0.604590924030283 0.874266061128759 0.874266061128759 0.874266061128759
Lrp8 ENSMUSG00000028613 0.974744804383567 0.974744804383567 0.959022400634642 0.974744804383567 0.833947892490056 0.974744804383567
Cdk5 ENSMUSG00000028969 0.300232142901528 0.406670832675747 0.110115347685398 0.330346043056195 0.406670832675747 0.406670832675747
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Rho ENSMUSG00000030324 0.757266463676936 0.836801121052075 0.836801121052075 0.836801121052075 0.378777142477677 0.836801121052075
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Cx3cl1 ENSMUSG00000031778 0.95593673909406 0.95593673909406 0.561519337590622 0.95593673909406 0.877665688727172 0.95593673909406
Pde4a ENSMUSG00000032177 0.588471243544624 0.946495883723625 0.893258499662348 0.946495883723625 0.946495883723625 0.946495883723625
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Sstr1 ENSMUSG00000035431 0.406238592066445 0.964057292265133 0.964057292265133 0.964057292265133 0.783863340301641 0.964057292265133
Npy1r ENSMUSG00000036437 0.404299171034672 0.952738532723292 0.952738532723292 0.952738532723292 0.911889505521477 0.952738532723292
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Apln ENSMUSG00000037010 0.75810612490527 0.75810612490527 0.661208628433793 0.75810612490527 0.675573817300198 0.75810612490527
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Gpr37 ENSMUSG00000039904 0.966888860531268 0.966888860531268 0.728518758974939 0.966888860531268 0.655532904753802 0.966888860531268
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Gnaz ENSMUSG00000040009 0.962224223006575 0.977957684590496 0.731228765255929 0.977957684590496 0.977957684590496 0.977957684590496
Chrm4 ENSMUSG00000040495 0.713559919137436 0.713559919137436 0.653668107827576 0.713559919137436 0.639519564436859 0.713559919137436
C3ar1 ENSMUSG00000040552 0.000211666510129739 0.000634999530389216 0.478720811527367 0.71808121729105 0.864363428489762 0.864363428489762
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Rgs8 ENSMUSG00000042671 0.774985743116201 0.774985743116201 0.740219182393667 0.774985743116201 0.545107546687497 0.774985743116201
Cnr1 ENSMUSG00000044288 0.745786054078664 0.949484405913581 0.793882327064725 0.949484405913581 0.949484405913581 0.949484405913581
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
S1pr5 ENSMUSG00000045087 0.581310188081916 0.940038730735353 0.830636858120185 0.940038730735353 0.940038730735353 0.940038730735353
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Penk ENSMUSG00000045573 0.803570970818424 0.959069192685323 0.877609538741843 0.959069192685323 0.959069192685323 0.959069192685323
Rbp1 ENSMUSG00000046402 0.442535096581074 0.442535096581074 0.383489069576458 0.442535096581074 0.0959674156358975 0.287902246907693
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Oprd1 ENSMUSG00000050511 0.843607928113184 0.887326964308433 0.802723620517678 0.887326964308433 0.887326964308433 0.887326964308433
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gpr17 ENSMUSG00000052229 0.841592903524789 0.841592903524789 0.735388479275896 0.841592903524789 0.818830393220439 0.841592903524789
Gper1 ENSMUSG00000053647 0.340734658300866 0.5111019874513 0.305493224887898 0.5111019874513 0.580124431812303 0.580124431812303
Grm7 ENSMUSG00000056755 0.858717824204382 0.977471956051544 0.625073995050131 0.977471956051544 0.977471956051544 0.977471956051544
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gpc6 ENSMUSG00000058571 0.849736318902451 0.849736318902451 0.474621122847807 0.71193168427171 0.344727157926739 0.71193168427171
Pde1a ENSMUSG00000059173 0.441062109163221 0.661593163744831 0.322985622028725 0.661593163744831 0.678510905331672 0.678510905331672
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Gm13306 ENSMUSG00000073877 0.316304878030798 0.554270327907138 0.727562091395151 0.727562091395151 0.369513551938092 0.554270327907138
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Assembly and cell surface presentation of NMDA receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Grin2c ENSMUSG00000020734 0.599025813656698 0.763130959764919 0.663079730373634 0.763130959764919 0.763130959764919 0.763130959764919
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Grin3a ENSMUSG00000039579 0.724435503006919 0.874406717817513 0.874406717817513 0.874406717817513 0.814103638083685 0.874406717817513
Grin2a ENSMUSG00000059003 0.794724556915648 0.921096664881798 0.706667092607556 0.921096664881798 0.921096664881798 0.921096664881798

Chondroitin sulfate/dermatan sulfate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
Chpf ENSMUSG00000032997 0.564224804621702 0.6900920474379 0.208182709704908 0.624548129114723 0.6900920474379 0.6900920474379
Chst11 ENSMUSG00000034612 0.984256392355295 0.984256392355295 0.797508779874515 0.984256392355295 0.722386232610309 0.984256392355295
Ids ENSMUSG00000035847 0.752170423358241 0.865239492021174 0.6901106916261 0.865239492021174 0.865239492021174 0.865239492021174
Csgalnact1 ENSMUSG00000036356 0.806651935197191 0.806651935197191 0.472105688923919 0.708158533385879 0.40216403146488 0.708158533385879
Dsel ENSMUSG00000038702 0.509525540837967 0.764288311256951 0.852843880920312 0.852843880920312 0.357090822300544 0.764288311256951
B3gat1 ENSMUSG00000045994 0.941590686501319 0.941590686501319 0.629538054037159 0.941590686501319 0.606171417556667 0.941590686501319
Chst9 ENSMUSG00000047161 0.957554377690628 0.957554377690628 0.728540340034293 0.957554377690628 0.818496706251111 0.957554377690628
Ust ENSMUSG00000047712 0.604589912333844 0.906884868500765 0.981069060734272 0.981069060734272 0.563307748957533 0.906884868500765
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
Chsy3 ENSMUSG00000058152 0.436347634369614 0.654521451554421 0.772914190509357 0.772914190509357 0.36263116795407 0.654521451554421
Gpc6 ENSMUSG00000058571 0.849736318902451 0.849736318902451 0.474621122847807 0.71193168427171 0.344727157926739 0.71193168427171
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689

G alpha (q) signalling events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dgke ENSMUSG00000000276 0.438701356587272 0.93393028681949 0.93393028681949 0.93393028681949 0.641220236857371 0.93393028681949
Ccl6 ENSMUSG00000018927 0.971654522167911 0.971654522167911 0.78821263178141 0.971654522167911 0.87446006544789 0.971654522167911
Ccl9 ENSMUSG00000019122 0.868342576542606 0.868342576542606 0.638411734452223 0.868342576542606 0.755133023615109 0.868342576542606
Rgs17 ENSMUSG00000019775 0.44498415891806 0.927455121576114 0.625935665673364 0.927455121576114 0.927455121576114 0.927455121576114
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Nmbr ENSMUSG00000019865 0.592774912955548 0.944018380658151 0.754309607011397 0.944018380658151 0.944018380658151 0.944018380658151
Ntsr2 ENSMUSG00000020591 1 1 0.958561123765929 1 0.933224198368138 1
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Dgkg ENSMUSG00000022861 0.833650333926293 0.839891174827249 0.839891174827249 0.839891174827249 0.721688536261811 0.839891174827249
Grp ENSMUSG00000024517 0.722584098475009 0.990287032276337 0.990287032276337 0.990287032276337 0.906223610168785 0.990287032276337
Tac2 ENSMUSG00000025400 0.783864107879587 0.783864107879587 0.362610864480765 0.708757538619127 0.472505025746085 0.708757538619127
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Tacr3 ENSMUSG00000028172 0.86353619522057 0.960980457908582 0.830458999836668 0.960980457908582 0.960980457908582 0.960980457908582
Pik3r3 ENSMUSG00000028698 0.173155016272897 0.519465048818692 0.646966884144507 0.927676116984635 0.927676116984635 0.927676116984635
Hcrtr1 ENSMUSG00000028778 0.776739267290508 0.776739267290508 0.483111972157679 0.776739267290508 0.534372493672934 0.776739267290508
Tacr1 ENSMUSG00000030043 0.874952532257405 0.990351663867859 0.990351663867859 0.990351663867859 0.910104110536735 0.990351663867859
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Grpr ENSMUSG00000031364 0.594100327338923 0.818349668482925 0.513345501338216 0.818349668482925 0.818349668482925 0.818349668482925
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Hcrtr2 ENSMUSG00000032360 0.964816963971967 0.977590851896125 0.658466283082889 0.977590851896125 0.977590851896125 0.977590851896125
Cck ENSMUSG00000032532 0.848947018692305 1 0.653741884609598 1 1 1
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Mgll ENSMUSG00000033174 0.574971563922836 0.678474080357625 0.0332923773738217 0.099877132121465 0.678474080357625 0.678474080357625
Dgkh ENSMUSG00000034731 0.388421388936085 0.869870998884137 0.579913999256091 0.869870998884137 0.971642477410861 0.971642477410861
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Dagla ENSMUSG00000035735 0.716365652254505 0.921367628058699 0.886972832447325 0.921367628058699 0.921367628058699 0.921367628058699
Kiss1r ENSMUSG00000035773 0.692593027585027 0.692593027585027 0.66927584815228 0.692593027585027 0.566498128060593 0.692593027585027
Dgkb ENSMUSG00000036095 0.530837257895833 0.958816829108309 0.958816829108309 0.958816829108309 0.780706242274577 0.958816829108309
Dgki ENSMUSG00000038665 0.534194562344775 0.923422221300899 0.83838067754833 0.923422221300899 0.923422221300899 0.923422221300899
Plcb4 ENSMUSG00000039943 0.420225368754993 0.874564378152378 0.874564378152378 0.874564378152378 0.773236484457488 0.874564378152378
Rgsl1 ENSMUSG00000042641 0.818410725782259 0.818410725782259 0.625499643529759 0.818410725782259 0.460032118785182 0.818410725782259
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Prokr2 ENSMUSG00000050558 0.980370352060819 0.980370352060819 0.764119976094218 0.980370352060819 0.882236886919263 0.980370352060819
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gpr17 ENSMUSG00000052229 0.841592903524789 0.841592903524789 0.735388479275896 0.841592903524789 0.818830393220439 0.841592903524789
Hrh1 ENSMUSG00000053004 0.870944697313483 0.870944697313483 0.578058362087012 0.870944697313483 0.64722556831022 0.870944697313483
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Tac1 ENSMUSG00000061762 0.917404416369368 0.917404416369368 0.761517449025984 0.917404416369368 0.737667215472087 0.917404416369368
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Post NMDA receptor activation events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

Norepinephrine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.618462531851883 0.830360028651728 0.659447901301229 0.830360028651728 0.830360028651728 0.830360028651728
Stx1a ENSMUSG00000007207 0.837357298110092 0.9716559340928 0.9716559340928 0.9716559340928 0.52484967065371 0.9716559340928
Ppfia4 ENSMUSG00000026458 0.313227115360254 0.763828470791961 0.577055496246566 0.763828470791961 0.763828470791961 0.763828470791961
Stxbp1 ENSMUSG00000026797 0.927670382913582 0.927670382913582 0.519748524673559 0.927670382913582 0.773230498403194 0.927670382913582
Unc13b ENSMUSG00000028456 0.915139340198681 0.99685085866835 0.99685085866835 0.99685085866835 0.569583717659663 0.99685085866835
Rab3a ENSMUSG00000031840 0.779273131687055 0.84354332538409 0.431743862876615 0.84354332538409 0.84354332538409 0.84354332538409
Cplx1 ENSMUSG00000033615 0.562853079135043 0.793287217497217 0.793287217497217 0.793287217497217 0.616407829684641 0.793287217497217
Bzrap1 ENSMUSG00000034156 0.545300101013927 0.921374275466458 0.641057582251148 0.921374275466458 0.921374275466458 0.921374275466458
Syt1 ENSMUSG00000035864 0.794246850953782 0.940090964079953 0.555291046308942 0.940090964079953 0.940090964079953 0.940090964079953

Vasopressin regulates renal water homeostasis via Aquaporins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aqp1 ENSMUSG00000004655 0.583040083630381 0.583040083630381 0.0887911890511459 0.266373567153438 0.52227431095088 0.583040083630381
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Aqp4 ENSMUSG00000024411 0.602220892440917 0.602220892440917 0.294684913700519 0.602220892440917 0.588533812029574 0.602220892440917
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Rab11fip2 ENSMUSG00000040022 0.746190402602984 0.770166676208484 0.734208835872967 0.770166676208484 0.770166676208484 0.770166676208484
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Transport of small molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Clcn4-2 ENSMUSG00000000605 0.707612911338539 0.707612911338539 0.658369528661635 0.707612911338539 0.550980836916718 0.707612911338539
Nr1h3 ENSMUSG00000002108 0.322973261470103 0.484459892205155 0.211057292397863 0.484459892205155 0.803604995305309 0.803604995305309
Angptl4 ENSMUSG00000002289 0.517125585196305 0.758176120614944 0.338745074699263 0.758176120614944 0.758176120614944 0.758176120614944
Slc2a3 ENSMUSG00000003153 0.828050614165109 0.940210361945226 0.868313739023565 0.940210361945226 0.940210361945226 0.940210361945226
Aqp1 ENSMUSG00000004655 0.583040083630381 0.583040083630381 0.0887911890511459 0.266373567153438 0.52227431095088 0.583040083630381
Slc25a18 ENSMUSG00000004902 0.835716796133805 0.856155552714375 0.856155552714375 0.856155552714375 0.307159790391501 0.856155552714375
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Slc4a3 ENSMUSG00000006576 0.955938803215994 0.955938803215994 0.632841118828259 0.949261678242388 0.632816340199223 0.949261678242388
Hfe ENSMUSG00000006611 0.618857520494464 0.788359576864546 0.722360812530259 0.788359576864546 0.788359576864546 0.788359576864546
Slc41a1 ENSMUSG00000013275 0.95907603967471 0.95907603967471 0.883904085603271 0.95907603967471 0.624323434982276 0.95907603967471
Slc9a5 ENSMUSG00000014786 0.64122605385598 0.785310179389001 0.588371391923136 0.785310179389001 0.785310179389001 0.785310179389001
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Slc12a5 ENSMUSG00000017740 0.996851063664395 0.996851063664395 0.251175722824672 0.753527168474017 0.599246759979626 0.898870139969439
Pltp ENSMUSG00000017754 0.0455782963784195 0.0683674445676292 0.0332961581676282 0.0683674445676292 0.661229852263671 0.661229852263671
Slc12a7 ENSMUSG00000017756 0.585810066458965 0.785352682969664 0.324905585919778 0.785352682969664 0.785352682969664 0.785352682969664
Abca5 ENSMUSG00000018800 0.371752951340952 0.661605431526956 0.441070287684638 0.661605431526956 0.678491171972215 0.678491171972215
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Atp6v0a1 ENSMUSG00000019302 0.809740608147782 0.955939962928653 0.569613013889838 0.955939962928653 0.955939962928653 0.955939962928653
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Slc16a10 ENSMUSG00000019838 0.509107823991209 0.763661735986814 0.257769197059797 0.763661735986814 0.852668566552395 0.852668566552395
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Slc1a4 ENSMUSG00000020142 0.887001249341426 0.887001249341426 0.509504424388217 0.887001249341426 0.638478258743037 0.887001249341426
Nipal4 ENSMUSG00000020411 0.689460493828345 0.977663836951691 0.977663836951691 0.977663836951691 0.503988589645247 0.977663836951691
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Fkbp1b ENSMUSG00000020635 0.67838623943518 0.94020814846731 0.734102818928033 0.94020814846731 0.94020814846731 0.94020814846731
Asic2 ENSMUSG00000020704 0.510167169387105 0.933459849010855 0.933459849010855 0.933459849010855 0.886317826003193 0.933459849010855
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Slc13a5 ENSMUSG00000020805 0.97124250220505 0.9840133569411 0.873045000478145 0.9840133569411 0.9840133569411 0.9840133569411
Cygb ENSMUSG00000020810 0.840478920351599 0.840478920351599 0.556281444226824 0.840478920351599 0.580390669403585 0.840478920351599
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Unc79 ENSMUSG00000021198 0.980753187729568 0.980753187729568 0.674692811057926 0.980753187729568 0.479763030544332 0.980753187729568
Slc25a29 ENSMUSG00000021265 0.055521500843306 0.166564502529918 0.298122597879254 0.447183896818882 0.791420714790527 0.791420714790527
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Atp8a2 ENSMUSG00000021983 0.791383700259054 0.88061164743568 0.88061164743568 0.88061164743568 0.689645488352171 0.88061164743568
Bmp1 ENSMUSG00000022098 0.737225020862538 0.737225020862538 0.580371415231663 0.737225020862538 0.268116819523234 0.737225020862538
Dmtn ENSMUSG00000022099 0.694532505051967 0.962032994500378 0.292371763774494 0.877115291323481 0.962032994500378 0.962032994500378
Slc22a17 ENSMUSG00000022199 0.424735815175521 0.591195084756444 0.591195084756444 0.591195084756444 0.558923807051274 0.591195084756444
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Apod ENSMUSG00000022548 0.713491763257087 0.785338603676536 0.664025880832068 0.785338603676536 0.785338603676536 0.785338603676536
Gpihbp1 ENSMUSG00000022579 0.791033639942828 0.791033639942828 0.781968601666039 0.791033639942828 0.518860917248302 0.791033639942828
Abcc5 ENSMUSG00000022822 0.61862596682725 0.868305327547924 0.868305327547924 0.868305327547924 0.624318706915158 0.868305327547924
Asic1 ENSMUSG00000023017 0.777597274978441 0.936566325083334 0.936566325083334 0.936566325083334 0.883035401165312 0.936566325083334
Atp6v0c ENSMUSG00000024121 0.440973349549293 0.66146002432394 0.127040125857152 0.381120377571457 0.692901294735045 0.692901294735045
Slc39a6 ENSMUSG00000024270 0.693003269675641 0.693003269675641 0.450488089338824 0.675732134008236 0.436330178764464 0.675732134008236
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
Aqp4 ENSMUSG00000024411 0.602220892440917 0.602220892440917 0.294684913700519 0.602220892440917 0.588533812029574 0.602220892440917
Npc1 ENSMUSG00000024413 0.890130303363091 0.962227042674884 0.908878815928368 0.962227042674884 0.962227042674884 0.962227042674884
Nedd4l ENSMUSG00000024589 0.822007967394219 0.930813745485442 0.871455644288866 0.930813745485442 0.930813745485442 0.930813745485442
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Slc29a2 ENSMUSG00000024891 0.507000988327154 0.693009715015452 0.658367097911268 0.693009715015452 0.693009715015452 0.693009715015452
Arl2 ENSMUSG00000024944 0.126088068282607 0.189132102423911 0.0203930921867576 0.0611792765602728 0.244794130470382 0.244794130470382
Atp10a ENSMUSG00000025324 0.899500358812645 0.899500358812645 0.698844544776835 0.899500358812645 0.770209816791198 0.899500358812645
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
9430016H08Rik ENSMUSG00000025971 0.79752032784118 0.79752032784118 0.0477897521479641 0.143369256443892 0.52743121171437 0.791146817571555
Slc9a4 ENSMUSG00000026065 0.816135961884783 0.816135961884783 0.499885151109367 0.816135961884783 0.766215783643848 0.816135961884783
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Slc45a3 ENSMUSG00000026435 0.386347769599559 0.579521654399339 0.175301827095698 0.525905481287093 1 1
Slc2a8 ENSMUSG00000026791 0.809742691994851 0.809742691994851 0.391168262042324 0.809742691994851 0.752161802363804 0.809742691994851
Stom ENSMUSG00000026880 0.658313536769352 0.893238118305959 0.812742406674574 0.893238118305959 0.893238118305959 0.893238118305959
Slc4a10 ENSMUSG00000026904 0.652785982436998 0.825971070312211 0.825971070312211 0.825971070312211 0.717883814347885 0.825971070312211
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Atp9a ENSMUSG00000027546 0.201099222239284 0.301648833358927 0.133088072724884 0.301648833358927 0.607674127473868 0.607674127473868
Slc7a11 ENSMUSG00000027737 0.390963664496459 0.930732216776983 0.930732216776983 0.930732216776983 0.622668968095726 0.930732216776983
Trpc4 ENSMUSG00000027748 0.767576880979932 0.888006864533746 0.888006864533746 0.888006864533746 0.815818518453809 0.888006864533746
Abca4 ENSMUSG00000028125 0.317815787275002 0.874266061128759 0.604590924030283 0.874266061128759 0.874266061128759 0.874266061128759
Slc44a5 ENSMUSG00000028360 0.44268732470733 0.870133623508318 0.864022214849736 0.870133623508318 0.870133623508318 0.870133623508318
Aqp7 ENSMUSG00000028427 0.977629744194963 0.977629744194963 0.514492638704463 0.785363421843548 0.523575614562365 0.785363421843548
Cyb5rl ENSMUSG00000028621 0.22597448715759 0.341180560416562 0.227453706944375 0.341180560416562 0.684263651852836 0.684263651852836
Abcb8 ENSMUSG00000028973 0.000769514485034907 0.00115427172755236 0.000258923801137127 0.000776771403411381 0.179367867140878 0.179367867140878
Clcn6 ENSMUSG00000029016 0.602216997152318 0.690094410971729 0.690094410971729 0.690094410971729 0.411130911175742 0.690094410971729
Slc10a6 ENSMUSG00000029321 0.00020785750607984 0.000623572518239521 0.958985610658061 0.958985610658061 0.483312094770042 0.724968142155062
Abcb9 ENSMUSG00000029408 0.417857512517685 0.626786268776528 0.055532970800435 0.166598912401305 0.96851665714292 0.96851665714292
Slc13a4 ENSMUSG00000029843 0.738208360270458 0.980668277049721 0.674006052143163 0.980668277049721 0.980668277049721 0.980668277049721
Add2 ENSMUSG00000030000 0.889210172309404 0.892435417101935 0.778433020019593 0.892435417101935 0.892435417101935 0.892435417101935
A2m ENSMUSG00000030111 0.9326152276123 0.9326152276123 0.585537805984835 0.878306708977253 0.553750045386439 0.878306708977253
Slco1c1 ENSMUSG00000030235 0.398107738783744 0.787824999652156 0.525216666434771 0.787824999652156 0.795312038016927 0.795312038016927
Slco1a4 ENSMUSG00000030237 0.613078471477568 0.781981054944562 0.781981054944562 0.781981054944562 0.663462721574924 0.781981054944562
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc6a11 ENSMUSG00000030307 0.647340804263377 0.79264831693501 0.79264831693501 0.79264831693501 0.731394235226783 0.79264831693501
Slc6a1 ENSMUSG00000030310 0.936745147043802 0.936745147043802 0.631296277368428 0.936745147043802 0.90197114705006 0.936745147043802
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Ttyh1 ENSMUSG00000030428 0.749151834313921 0.809640941211619 0.800468422733356 0.809640941211619 0.809640941211619 0.809640941211619
Slc7a10 ENSMUSG00000030495 0.617216518815915 0.624619381552089 0.624619381552089 0.624619381552089 0.400163987845447 0.624619381552089
Slc7a3 ENSMUSG00000031297 0.864966665985726 0.864966665985726 0.858371595970544 0.864966665985726 0.790441108300969 0.864966665985726
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Abcg4 ENSMUSG00000032131 0.901882869975478 0.901882869975478 0.601518469194952 0.901882869975478 0.805168659922071 0.901882869975478
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Slc16a1 ENSMUSG00000032902 0.755100736265865 0.755100736265865 0.0300290400436083 0.090087120130825 0.422268621151675 0.633402931727513
Asic4 ENSMUSG00000033007 0.505425191865474 0.959284275176646 0.959284275176646 0.959284275176646 0.785101439020239 0.959284275176646
Ano8 ENSMUSG00000034863 0.713541322970901 0.852840356072577 0.2715177680512 0.814553304153599 0.852840356072577 0.852840356072577
Ano4 ENSMUSG00000035189 0.722081088232675 0.952754072966194 0.580174575196395 0.952754072966194 0.952754072966194 0.952754072966194
Slc2a13 ENSMUSG00000036298 0.496560842909563 0.858862866563135 0.858862866563135 0.858862866563135 0.73374130153953 0.858862866563135
Skp1a ENSMUSG00000036309 0.843556157040784 0.843556157040784 0.831232339372914 0.843556157040784 0.837382337350301 0.843556157040784
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fxyd7 ENSMUSG00000036578 0.429266975420368 0.6103666140928 0.342717167898781 0.6103666140928 0.6103666140928 0.6103666140928
Best1 ENSMUSG00000037418 0.571417148101941 0.571417148101941 0.281445780646213 0.51764628387499 0.345097522583327 0.51764628387499
Slc9b2 ENSMUSG00000037994 0.873722303943736 0.873722303943736 0.598230225640073 0.873722303943736 0.49585264750005 0.873722303943736
Slc24a2 ENSMUSG00000037996 0.54200427865392 0.957631678136051 0.957631678136051 0.957631678136051 0.739133554902329 0.957631678136051
Ano2 ENSMUSG00000038115 0.768061684974316 0.977259961252702 0.960916822645437 0.977259961252702 0.977259961252702 0.977259961252702
Atp6v0e2 ENSMUSG00000039347 0.375988428021386 0.563982642032079 0.307534606168789 0.563982642032079 0.746086632625595 0.746086632625595
Micu3 ENSMUSG00000039478 0.481965029611063 0.722947544416594 0.415617218120238 0.722947544416594 0.915130815365557 0.915130815365557
Rab11fip2 ENSMUSG00000040022 0.746190402602984 0.770166676208484 0.734208835872967 0.770166676208484 0.770166676208484 0.770166676208484
Slc26a7 ENSMUSG00000040569 0.898183482654752 0.898183482654752 0.834850210740357 0.898183482654752 0.702500444828441 0.898183482654752
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Wnk3 ENSMUSG00000041245 0.440488308398889 0.87516313668841 0.87516313668841 0.87516313668841 0.849686330194986 0.87516313668841
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Slc24a4 ENSMUSG00000041771 0.817684759159923 0.817684759159923 0.474003798142661 0.817684759159923 0.608807387018037 0.817684759159923
Lrrc8e ENSMUSG00000046589 0.156278952697889 0.468836858093667 0.322891465427099 0.484337198140648 0.724026989797481 0.724026989797481
Slc39a3 ENSMUSG00000046822 0.23370198670225 0.350552980053375 0.21843989653955 0.350552980053375 0.427115347994381 0.427115347994381
Nipa1 ENSMUSG00000047037 0.763917686092079 0.763917686092079 0.424751471058166 0.763917686092079 0.596292946610677 0.763917686092079
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Slc29a4 ENSMUSG00000050822 0.791208467833972 0.871205424634556 0.871205424634556 0.871205424634556 0.837222769683849 0.871205424634556
Slc6a7 ENSMUSG00000052026 0.665798861742321 0.980966838363542 0.980966838363542 0.980966838363542 0.557176824775787 0.980966838363542
Trpm3 ENSMUSG00000052387 0.772840088272938 0.772840088272938 0.757726111335929 0.772840088272938 0.742668691056734 0.772840088272938
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Zdhhc8 ENSMUSG00000060166 0.761185380208224 0.99685122678873 0.84665661450784 0.99685122678873 0.99685122678873 0.99685122678873
Slc9a6 ENSMUSG00000060681 0.610516407664385 0.915774611496577 0.952794664966752 0.952794664966752 0.499404338173162 0.915774611496577
Slc24a3 ENSMUSG00000063873 0.933948902380247 0.933948902380247 0.602016601246533 0.933948902380247 0.737091500661524 0.933948902380247
Fxyd6 ENSMUSG00000066705 0.604968393504201 0.644142732695471 0.37816156867391 0.644142732695471 0.644142732695471 0.644142732695471
Slc4a5 ENSMUSG00000068323 0.602446444827455 0.854760459903678 0.813500573907216 0.854760459903678 0.854760459903678 0.854760459903678
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Slc39a2 ENSMUSG00000072572 0.348503999750023 0.72509089866815 0.632339595075231 0.72509089866815 0.72509089866815 0.72509089866815
Ano3 ENSMUSG00000074968 0.854782395692694 0.986460865181157 0.986460865181157 0.986460865181157 0.654222725900705 0.986460865181157
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504
AA474331 ENSMUSG00000096687 0.309535480330721 0.928606440992164 0.933945664741925 0.933945664741925 0.737197767580212 0.933945664741925
LRRC8A ENSMUSG00000099041 0.821996632243041 0.821996632243041 0.684287246812588 0.821996632243041 0.517178720805829 0.821996632243041

NRAGE signals death through JNK

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Arhgef40 ENSMUSG00000004562 0.690115975723052 0.734258969628961 0.734258969628961 0.734258969628961 0.344799955228746 0.734258969628961
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Tiam2 ENSMUSG00000023800 0.862097039059075 0.862097039059075 0.644127593764966 0.862097039059075 0.687109235269195 0.862097039059075
Fgd1 ENSMUSG00000025265 0.618850897072831 0.943366293933116 0.806686983694517 0.943366293933116 0.943366293933116 0.943366293933116
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Arhgef17 ENSMUSG00000032875 0.902626804113539 0.91513128746116 0.722365064561738 0.91513128746116 0.91513128746116 0.91513128746116
Arhgef26 ENSMUSG00000036885 0.338744587725774 0.624404520746658 0.624404520746658 0.624404520746658 0.556253327919585 0.624404520746658
Plekhg5 ENSMUSG00000039713 0.779235921324691 0.779235921324691 0.749170734286215 0.779235921324691 0.519662892686707 0.779235921324691
Arhgef15 ENSMUSG00000052921 0.678504395758495 0.678504395758495 0.397719918405541 0.678504395758495 0.545704084312357 0.678504395758495
Arhgef33 ENSMUSG00000054901 0.724651036641199 0.951403625820301 0.951403625820301 0.951403625820301 0.762641987834789 0.951403625820301
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Arhgef10 ENSMUSG00000071176 0.828121266477381 0.828121266477381 0.558870934116684 0.828121266477381 0.357078975694619 0.828121266477381

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnc2 ENSMUSG00000035681 0.77883546096691 0.97792918719802 0.849660122239855 0.97792918719802 0.97792918719802 0.97792918719802
Kcns3 ENSMUSG00000043673 0.701665159685762 0.886989865092589 0.886989865092589 0.886989865092589 0.73420623557152 0.886989865092589
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Rapgef4 ENSMUSG00000049044 0.965372920310892 0.965372920310892 0.859037017579714 0.965372920310892 0.767193840007081 0.965372920310892
Kcnb1 ENSMUSG00000050556 0.63829206364259 0.779166422839317 0.779166422839317 0.779166422839317 0.763965984884611 0.779166422839317
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Adenylate cyclase activating pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246

Glycosaminoglycan metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Has1 ENSMUSG00000003665 0.393828888721476 0.637549750409593 0.693069727377616 0.693069727377616 0.425033166939729 0.637549750409593
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Abcc5 ENSMUSG00000022822 0.61862596682725 0.868305327547924 0.868305327547924 0.868305327547924 0.624318706915158 0.868305327547924
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Chst1 ENSMUSG00000027221 0.87448918402456 0.87448918402456 0.596618568703235 0.87448918402456 0.678408062180025 0.87448918402456
Ndst3 ENSMUSG00000027977 0.660777196351522 0.857130114130428 0.857130114130428 0.857130114130428 0.636488911543187 0.857130114130428
B4galt1 ENSMUSG00000028413 0.752176420041432 0.974813741144869 0.57497938457053 0.974813741144869 0.974813741144869 0.974813741144869
B4galt2 ENSMUSG00000028541 0.818935849510673 0.818935849510673 0.3933181046077 0.818935849510673 0.572250683911185 0.818935849510673
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
St3gal2 ENSMUSG00000031749 0.971666131040263 0.971666131040263 0.30208509455634 0.906255283669021 0.661244294967828 0.971666131040263
Has3 ENSMUSG00000031910 0.390710423679248 0.937066034037017 0.937066034037017 0.937066034037017 0.672608051394116 0.937066034037017
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
Chpf ENSMUSG00000032997 0.564224804621702 0.6900920474379 0.208182709704908 0.624548129114723 0.6900920474379 0.6900920474379
Chst2 ENSMUSG00000033350 0.658361485539787 0.924538106334966 0.388976344507304 0.924538106334966 0.924538106334966 0.924538106334966
Chst11 ENSMUSG00000034612 0.984256392355295 0.984256392355295 0.797508779874515 0.984256392355295 0.722386232610309 0.984256392355295
Ids ENSMUSG00000035847 0.752170423358241 0.865239492021174 0.6901106916261 0.865239492021174 0.865239492021174 0.865239492021174
Csgalnact1 ENSMUSG00000036356 0.806651935197191 0.806651935197191 0.472105688923919 0.708158533385879 0.40216403146488 0.708158533385879
Dsel ENSMUSG00000038702 0.509525540837967 0.764288311256951 0.852843880920312 0.852843880920312 0.357090822300544 0.764288311256951
Hs2st1 ENSMUSG00000040151 0.899501307549021 0.899501307549021 0.332799292083218 0.899501307549021 0.776273209817288 0.899501307549021
Hs3st5 ENSMUSG00000044499 0.853996311088547 0.853996311088547 0.74123195090548 0.853996311088547 0.686076751806097 0.853996311088547
B3gat1 ENSMUSG00000045994 0.941590686501319 0.941590686501319 0.629538054037159 0.941590686501319 0.606171417556667 0.941590686501319
Hs3st2 ENSMUSG00000046321 0.838947706921784 0.996776192162678 0.996776192162678 0.996776192162678 0.967653626333733 0.996776192162678
Chst9 ENSMUSG00000047161 0.957554377690628 0.957554377690628 0.728540340034293 0.957554377690628 0.818496706251111 0.957554377690628
B3gnt1 ENSMUSG00000047379 0.294691733148561 0.442037599722842 0.0429821157516396 0.128946347254919 0.707547845600778 0.707547845600778
Ust ENSMUSG00000047712 0.604589912333844 0.906884868500765 0.981069060734272 0.981069060734272 0.563307748957533 0.906884868500765
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
B4galt6 ENSMUSG00000056124 0.443308957965952 0.771897274521459 0.514598183014306 0.771897274521459 0.79139353629991 0.79139353629991
Chsy3 ENSMUSG00000058152 0.436347634369614 0.654521451554421 0.772914190509357 0.772914190509357 0.36263116795407 0.654521451554421
Gpc6 ENSMUSG00000058571 0.849736318902451 0.849736318902451 0.474621122847807 0.71193168427171 0.344727157926739 0.71193168427171
Hs6st2 ENSMUSG00000062184 0.85887458944601 0.962178028086868 0.962178028086868 0.962178028086868 0.896335063174007 0.962178028086868
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689
Hs3st4 ENSMUSG00000078591 0.480944767352871 0.871889000176109 0.871889000176109 0.871889000176109 0.846807002613367 0.871889000176109

COPI-independent Golgi-to-ER retrograde traffic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Pafah1b2 ENSMUSG00000003131 0.632845526771685 0.658369242693692 0.658369242693692 0.658369242693692 0.537862074916216 0.658369242693692
Bicd1 ENSMUSG00000003452 0.283785064163411 0.851355192490233 0.604924361791458 0.902625852142877 0.902625852142877 0.902625852142877
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Pafah1b1 ENSMUSG00000020745 0.684268257790379 0.89324127106958 0.496924413629147 0.89324127106958 0.89324127106958 0.89324127106958
Actr10 ENSMUSG00000021076 0.669849228095005 0.695941807023691 0.695941807023691 0.695941807023691 0.535250403728396 0.695941807023691
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Dync1i1 ENSMUSG00000029757 0.812594681821339 0.927644345002271 0.927644345002271 0.927644345002271 0.666543997730284 0.927644345002271
Rab6a ENSMUSG00000030704 0.20235419478262 0.607062584347861 0.504459448302574 0.756689172453862 0.949638229210331 0.949638229210331
Rab6b ENSMUSG00000032549 0.664103193346801 0.818936127655932 0.701795171667842 0.818936127655932 0.818936127655932 0.818936127655932
Dync1li2 ENSMUSG00000035770 0.535252137809611 0.933945421899857 0.831224283473137 0.933945421899857 0.933945421899857 0.933945421899857
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516
Rab18 ENSMUSG00000073639 0.221389310434858 0.59989284241998 0.605000994153659 0.605000994153659 0.39992856161332 0.59989284241998

Cell death signalling via NRAGE, NRIF and NADE

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Arhgef40 ENSMUSG00000004562 0.690115975723052 0.734258969628961 0.734258969628961 0.734258969628961 0.344799955228746 0.734258969628961
Sqstm1 ENSMUSG00000015837 0.548220980587803 0.822331470881704 0.0231457389756086 0.0694372169268258 0.974803078046978 0.974803078046978
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Tiam2 ENSMUSG00000023800 0.862097039059075 0.862097039059075 0.644127593764966 0.862097039059075 0.687109235269195 0.862097039059075
Fgd1 ENSMUSG00000025265 0.618850897072831 0.943366293933116 0.806686983694517 0.943366293933116 0.943366293933116 0.943366293933116
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Arhgef17 ENSMUSG00000032875 0.902626804113539 0.91513128746116 0.722365064561738 0.91513128746116 0.91513128746116 0.91513128746116
Arhgef26 ENSMUSG00000036885 0.338744587725774 0.624404520746658 0.624404520746658 0.624404520746658 0.556253327919585 0.624404520746658
Plekhg5 ENSMUSG00000039713 0.779235921324691 0.779235921324691 0.749170734286215 0.779235921324691 0.519662892686707 0.779235921324691
Ngfrap1 ENSMUSG00000046432 0.946506652154109 0.946506652154109 0.613269482237527 0.946506652154109 0.849734644219946 0.946506652154109
Arhgef15 ENSMUSG00000052921 0.678504395758495 0.678504395758495 0.397719918405541 0.678504395758495 0.545704084312357 0.678504395758495
Arhgef33 ENSMUSG00000054901 0.724651036641199 0.951403625820301 0.951403625820301 0.951403625820301 0.762641987834789 0.951403625820301
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Arhgef10 ENSMUSG00000071176 0.828121266477381 0.828121266477381 0.558870934116684 0.828121266477381 0.357078975694619 0.828121266477381

MAPK family signaling cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Pea15a ENSMUSG00000013698 0.737241300937761 0.737241300937761 0.616073413108655 0.737241300937761 0.514625923838225 0.737241300937761
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Etv4 ENSMUSG00000017724 0.874558016424449 0.874558016424449 0.695936643601099 0.874558016424449 0.782316346957673 0.874558016424449
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Nf1 ENSMUSG00000020716 0.371683595114246 0.690103142447791 0.690103142447791 0.690103142447791 0.669823684327671 0.690103142447791
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Frs3 ENSMUSG00000023266 0.877673101799547 0.974813738333914 0.974813738333914 0.974813738333914 0.71352514240849 0.974813738333914
Mapk4 ENSMUSG00000024558 0.806530790810286 0.971645979639665 0.776168664106968 0.971645979639665 0.971645979639665 0.971645979639665
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Arl2 ENSMUSG00000024944 0.126088068282607 0.189132102423911 0.0203930921867576 0.0611792765602728 0.244794130470382 0.244794130470382
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Cnksr2 ENSMUSG00000025658 0.899667566749859 0.899667566749859 0.690719928069651 0.899667566749859 0.782271280971245 0.899667566749859
Lypla1 ENSMUSG00000025903 0.474557263496955 0.711906776508762 0.474604517672508 0.711906776508762 0.9088641950551 0.9088641950551
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Dab2ip ENSMUSG00000026883 0.908880355624594 0.908880355624594 0.352946406311928 0.908880355624594 0.701754095193645 0.908880355624594
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Spred1 ENSMUSG00000027351 0.427124606838286 0.764198756499969 0.764198756499969 0.764198756499969 0.710594119338658 0.764198756499969
Rasal1 ENSMUSG00000029602 0.549673540060143 0.949318299879298 0.72963301255346 0.949318299879298 0.949318299879298 0.949318299879298
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Rasgef1a ENSMUSG00000030134 0.630009345487522 0.731264730491952 0.731264730491952 0.731264730491952 0.675592754208279 0.731264730491952
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Pebp1 ENSMUSG00000032959 0.285581660641493 0.428372490962239 0.0941657923655824 0.282497377096747 0.580367267833894 0.580367267833894
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Dusp8 ENSMUSG00000037887 0.413364084032459 0.620046126048688 0.23839621310406 0.620046126048688 0.852819445432281 0.852819445432281
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Kbtbd7 ENSMUSG00000043881 0.883904214304574 0.883904214304574 0.340772248229217 0.883904214304574 0.644136107337212 0.883904214304574
Spred2 ENSMUSG00000045671 0.776269634904547 0.80057783665013 0.585828497213068 0.80057783665013 0.80057783665013 0.80057783665013
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Paqr3 ENSMUSG00000055725 0.767133515203126 0.877668656828336 0.658299945831767 0.877668656828336 0.877668656828336 0.877668656828336
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Rapgef2 ENSMUSG00000062232 0.532650093135441 0.843568313157742 0.825066402286463 0.843568313157742 0.843568313157742 0.843568313157742
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Syngap1 ENSMUSG00000067629 0.49917993882886 0.865184883031372 0.728298167799716 0.865184883031372 0.865184883031372 0.865184883031372
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Rasal2 ENSMUSG00000070565 0.375974690480065 0.837354234576499 0.837354234576499 0.837354234576499 0.690066143506778 0.837354234576499

O-glycosylation of TSR domain-containing proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adamts4 ENSMUSG00000006403 0.377538354290343 0.377538354290343 0.131753214662637 0.374250047837577 0.249500031891718 0.374250047837577
Adamts20 ENSMUSG00000022449 0.876829053650104 0.876829053650104 0.783948088691439 0.876829053650104 0.814876943304248 0.876829053650104
Thsd4 ENSMUSG00000032289 0.725227531364508 0.77264905366802 0.757472256002231 0.77264905366802 0.77264905366802 0.77264905366802
Adamts2 ENSMUSG00000036545 0.740068907870709 0.809653316848382 0.564255333775472 0.809653316848382 0.809653316848382 0.809653316848382
Spon2 ENSMUSG00000037379 0.67172740506514 0.67172740506514 0.403078707219161 0.604618060828742 0.266445100439898 0.604618060828742
Spon1 ENSMUSG00000038156 0.797375791778427 0.840476811612271 0.815747218082904 0.840476811612271 0.840476811612271 0.840476811612271
Thsd7b ENSMUSG00000042581 0.873832676949942 0.873832676949942 0.475684674848232 0.873832676949942 0.848600456181496 0.873832676949942
Adamts3 ENSMUSG00000043635 0.788097658314988 0.87429794279683 0.87429794279683 0.87429794279683 0.715459829558953 0.87429794279683
Adamts16 ENSMUSG00000049538 0.283106261449117 0.820211173119244 0.820211173119244 0.820211173119244 0.725603971168321 0.820211173119244
Sema5b ENSMUSG00000052133 0.8652255403839 0.949625150311005 0.672591225673965 0.949625150311005 0.949625150311005 0.949625150311005
Adamts18 ENSMUSG00000053399 0.803841246301092 0.977206305861151 0.909251928532732 0.977206305861151 0.977206305861151 0.977206305861151
Adamts19 ENSMUSG00000053441 0.788708353036202 0.964868616680012 0.964868616680012 0.964868616680012 0.527996648565404 0.964868616680012
Adamts17 ENSMUSG00000058145 0.977890301251322 0.977890301251322 0.965068200851174 0.977890301251322 0.930235329525859 0.977890301251322
Adamtsl1 ENSMUSG00000066113 0.924496212052139 0.97794730398435 0.97794730398435 0.97794730398435 0.797524375798662 0.97794730398435

Activation of RAC1 downstream of NMDARs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Camk1 ENSMUSG00000030272 0.504450487544428 0.756675731316642 0.472186572113071 0.756675731316642 0.981107870184178 0.981107870184178
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

Trafficking of GluR2-containing AMPA receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gria3 ENSMUSG00000001986 0.684181478810865 0.930796333980694 0.930796333980694 0.930796333980694 0.56420511624778 0.930796333980694
Gria1 ENSMUSG00000020524 0.923189009017009 0.974217220047435 0.974217220047435 0.974217220047435 0.848189093389644 0.974217220047435
Gria4 ENSMUSG00000025892 0.968320930676499 0.968320930676499 0.942916681651699 0.968320930676499 0.799136575049445 0.968320930676499
Grip2 ENSMUSG00000030098 0.990552373447678 0.990552373447678 0.776259346954886 0.990552373447678 0.764148401525939 0.990552373447678
Nsf ENSMUSG00000034187 0.681394277271168 0.7253443570495 0.406672985784594 0.7253443570495 0.7253443570495 0.7253443570495
Grip1 ENSMUSG00000034813 0.787315588271143 0.870811745501415 0.870811745501415 0.870811745501415 0.772213919041615 0.870811745501415
Tspan7 ENSMUSG00000058254 0.70471768991258 0.959084133781236 0.168197703770895 0.504593111312684 0.959084133781236 0.959084133781236
Prkcg ENSMUSG00000078816 0.40443464422824 0.722392950670366 0.632851834415264 0.722392950670366 0.722392950670366 0.722392950670366

Aquaporin-mediated transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aqp1 ENSMUSG00000004655 0.583040083630381 0.583040083630381 0.0887911890511459 0.266373567153438 0.52227431095088 0.583040083630381
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Aqp4 ENSMUSG00000024411 0.602220892440917 0.602220892440917 0.294684913700519 0.602220892440917 0.588533812029574 0.602220892440917
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Aqp7 ENSMUSG00000028427 0.977629744194963 0.977629744194963 0.514492638704463 0.785363421843548 0.523575614562365 0.785363421843548
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Rab11fip2 ENSMUSG00000040022 0.746190402602984 0.770166676208484 0.734208835872967 0.770166676208484 0.770166676208484 0.770166676208484
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

EPH-Ephrin signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Pak3 ENSMUSG00000031284 0.388697380128585 0.860126978981254 0.860126978981254 0.860126978981254 0.845039498351271 0.860126978981254
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904

Ion channel transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Clcn4-2 ENSMUSG00000000605 0.707612911338539 0.707612911338539 0.658369528661635 0.707612911338539 0.550980836916718 0.707612911338539
Atp6v1b2 ENSMUSG00000006273 0.779280480250472 0.797510439186653 0.641305897181812 0.797510439186653 0.797510439186653 0.797510439186653
Atp6v1e1 ENSMUSG00000019210 0.719436010119692 0.719436010119692 0.610367213131066 0.719436010119692 0.607629843278616 0.719436010119692
Atp6v0a1 ENSMUSG00000019302 0.809740608147782 0.955939962928653 0.569613013889838 0.955939962928653 0.955939962928653 0.955939962928653
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Fkbp1b ENSMUSG00000020635 0.67838623943518 0.94020814846731 0.734102818928033 0.94020814846731 0.94020814846731 0.94020814846731
Asic2 ENSMUSG00000020704 0.510167169387105 0.933459849010855 0.933459849010855 0.933459849010855 0.886317826003193 0.933459849010855
Atp6v1d ENSMUSG00000021114 0.134141486236624 0.402424458709873 0.404336744271533 0.606505116407299 0.952786197835012 0.952786197835012
Unc79 ENSMUSG00000021198 0.980753187729568 0.980753187729568 0.674692811057926 0.980753187729568 0.479763030544332 0.980753187729568
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Atp8a2 ENSMUSG00000021983 0.791383700259054 0.88061164743568 0.88061164743568 0.88061164743568 0.689645488352171 0.88061164743568
Atp6v1c1 ENSMUSG00000022295 0.666977901673285 0.880787503487908 0.880787503487908 0.880787503487908 0.646988610566428 0.880787503487908
Asic1 ENSMUSG00000023017 0.777597274978441 0.936566325083334 0.936566325083334 0.936566325083334 0.883035401165312 0.936566325083334
Atp6v0c ENSMUSG00000024121 0.440973349549293 0.66146002432394 0.127040125857152 0.381120377571457 0.692901294735045 0.692901294735045
Atp6v1g2 ENSMUSG00000024403 0.809718348390229 0.990553589672781 0.990553589672781 0.990553589672781 0.840458040147578 0.990553589672781
Nedd4l ENSMUSG00000024589 0.822007967394219 0.930813745485442 0.871455644288866 0.930813745485442 0.930813745485442 0.930813745485442
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Atp10a ENSMUSG00000025324 0.899500358812645 0.899500358812645 0.698844544776835 0.899500358812645 0.770209816791198 0.899500358812645
Stom ENSMUSG00000026880 0.658313536769352 0.893238118305959 0.812742406674574 0.893238118305959 0.893238118305959 0.893238118305959
Atp9a ENSMUSG00000027546 0.201099222239284 0.301648833358927 0.133088072724884 0.301648833358927 0.607674127473868 0.607674127473868
Trpc4 ENSMUSG00000027748 0.767576880979932 0.888006864533746 0.888006864533746 0.888006864533746 0.815818518453809 0.888006864533746
Clcn6 ENSMUSG00000029016 0.602216997152318 0.690094410971729 0.690094410971729 0.690094410971729 0.411130911175742 0.690094410971729
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Ttyh1 ENSMUSG00000030428 0.749151834313921 0.809640941211619 0.800468422733356 0.809640941211619 0.809640941211619 0.809640941211619
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Asic4 ENSMUSG00000033007 0.505425191865474 0.959284275176646 0.959284275176646 0.959284275176646 0.785101439020239 0.959284275176646
Ano8 ENSMUSG00000034863 0.713541322970901 0.852840356072577 0.2715177680512 0.814553304153599 0.852840356072577 0.852840356072577
Ano4 ENSMUSG00000035189 0.722081088232675 0.952754072966194 0.580174575196395 0.952754072966194 0.952754072966194 0.952754072966194
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Fxyd7 ENSMUSG00000036578 0.429266975420368 0.6103666140928 0.342717167898781 0.6103666140928 0.6103666140928 0.6103666140928
Best1 ENSMUSG00000037418 0.571417148101941 0.571417148101941 0.281445780646213 0.51764628387499 0.345097522583327 0.51764628387499
Slc9b2 ENSMUSG00000037994 0.873722303943736 0.873722303943736 0.598230225640073 0.873722303943736 0.49585264750005 0.873722303943736
Ano2 ENSMUSG00000038115 0.768061684974316 0.977259961252702 0.960916822645437 0.977259961252702 0.977259961252702 0.977259961252702
Atp6v0e2 ENSMUSG00000039347 0.375988428021386 0.563982642032079 0.307534606168789 0.563982642032079 0.746086632625595 0.746086632625595
Atp1a3 ENSMUSG00000040907 0.883745471148401 0.996845103889016 0.996845103889016 0.996845103889016 0.902556618856758 0.996845103889016
Wnk3 ENSMUSG00000041245 0.440488308398889 0.87516313668841 0.87516313668841 0.87516313668841 0.849686330194986 0.87516313668841
Atp1b2 ENSMUSG00000041329 0.890106486819376 0.890122878360418 0.627159713342136 0.890122878360418 0.890122878360418 0.890122878360418
Trpm3 ENSMUSG00000052387 0.772840088272938 0.772840088272938 0.757726111335929 0.772840088272938 0.742668691056734 0.772840088272938
Ryr3 ENSMUSG00000057378 0.937056116988582 0.937056116988582 0.877615306492476 0.937056116988582 0.776252219954633 0.937056116988582
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fxyd6 ENSMUSG00000066705 0.604968393504201 0.644142732695471 0.37816156867391 0.644142732695471 0.644142732695471 0.644142732695471
Ano3 ENSMUSG00000074968 0.854782395692694 0.986460865181157 0.986460865181157 0.986460865181157 0.654222725900705 0.986460865181157

Collagen biosynthesis and modifying enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Col26a1 ENSMUSG00000004415 0.40808844882637 0.855171667263473 0.730026149443398 0.855171667263473 0.855171667263473 0.855171667263473
Bmp1 ENSMUSG00000022098 0.737225020862538 0.737225020862538 0.580371415231663 0.737225020862538 0.268116819523234 0.737225020862538
Col14a1 ENSMUSG00000022371 0.946468990948881 0.946468990948881 0.222626767905235 0.606173596677163 0.404115731118109 0.606173596677163
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Leprel2 ENSMUSG00000023191 0.386742706478303 0.726697031759814 0.484464687839876 0.726697031759814 0.746182026849525 0.746182026849525
Tll2 ENSMUSG00000025013 0.903529078378002 0.903529078378002 0.894171408495149 0.903529078378002 0.370932636367097 0.903529078378002
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Col19a1 ENSMUSG00000026141 0.632979519083827 0.632979519083827 0.550670139639432 0.632979519083827 0.574090220657963 0.632979519083827
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Col11a1 ENSMUSG00000027966 0.620986530830078 0.863426484484914 0.863426484484914 0.863426484484914 0.817800235105334 0.863426484484914
Lepre1 ENSMUSG00000028641 0.162050328692884 0.243075493039326 0.0918102773153355 0.243075493039326 0.378086810083087 0.378086810083087
Col4a6 ENSMUSG00000031273 0.384104158371494 0.766743553616261 0.96846938071278 0.96846938071278 0.511162369077507 0.766743553616261
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Colgalt2 ENSMUSG00000032649 0.63279140450289 0.661223961098107 0.661223961098107 0.661223961098107 0.357056034572014 0.661223961098107
Adamts2 ENSMUSG00000036545 0.740068907870709 0.809653316848382 0.564255333775472 0.809653316848382 0.809653316848382 0.809653316848382
Col16a1 ENSMUSG00000040690 0.55362704634813 0.959081491056297 0.655505695107622 0.959081491056297 0.959081491056297 0.959081491056297
Adamts3 ENSMUSG00000043635 0.788097658314988 0.87429794279683 0.87429794279683 0.87429794279683 0.715459829558953 0.87429794279683
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Col23a1 ENSMUSG00000063564 0.758144768791638 0.890001683443621 0.809488290968811 0.890001683443621 0.890001683443621 0.890001683443621

Chondroitin sulfate biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
Chpf ENSMUSG00000032997 0.564224804621702 0.6900920474379 0.208182709704908 0.624548129114723 0.6900920474379 0.6900920474379
Chst11 ENSMUSG00000034612 0.984256392355295 0.984256392355295 0.797508779874515 0.984256392355295 0.722386232610309 0.984256392355295
Csgalnact1 ENSMUSG00000036356 0.806651935197191 0.806651935197191 0.472105688923919 0.708158533385879 0.40216403146488 0.708158533385879
Chst9 ENSMUSG00000047161 0.957554377690628 0.957554377690628 0.728540340034293 0.957554377690628 0.818496706251111 0.957554377690628
Chsy3 ENSMUSG00000058152 0.436347634369614 0.654521451554421 0.772914190509357 0.772914190509357 0.36263116795407 0.654521451554421

Dermatan sulfate biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
Dsel ENSMUSG00000038702 0.509525540837967 0.764288311256951 0.852843880920312 0.852843880920312 0.357090822300544 0.764288311256951
Ust ENSMUSG00000047712 0.604589912333844 0.906884868500765 0.981069060734272 0.981069060734272 0.563307748957533 0.906884868500765

RAF/MAP kinase cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Pea15a ENSMUSG00000013698 0.737241300937761 0.737241300937761 0.616073413108655 0.737241300937761 0.514625923838225 0.737241300937761
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Nf1 ENSMUSG00000020716 0.371683595114246 0.690103142447791 0.690103142447791 0.690103142447791 0.669823684327671 0.690103142447791
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Frs3 ENSMUSG00000023266 0.877673101799547 0.974813738333914 0.974813738333914 0.974813738333914 0.71352514240849 0.974813738333914
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Arl2 ENSMUSG00000024944 0.126088068282607 0.189132102423911 0.0203930921867576 0.0611792765602728 0.244794130470382 0.244794130470382
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Cnksr2 ENSMUSG00000025658 0.899667566749859 0.899667566749859 0.690719928069651 0.899667566749859 0.782271280971245 0.899667566749859
Lypla1 ENSMUSG00000025903 0.474557263496955 0.711906776508762 0.474604517672508 0.711906776508762 0.9088641950551 0.9088641950551
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Dab2ip ENSMUSG00000026883 0.908880355624594 0.908880355624594 0.352946406311928 0.908880355624594 0.701754095193645 0.908880355624594
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Spred1 ENSMUSG00000027351 0.427124606838286 0.764198756499969 0.764198756499969 0.764198756499969 0.710594119338658 0.764198756499969
Rasal1 ENSMUSG00000029602 0.549673540060143 0.949318299879298 0.72963301255346 0.949318299879298 0.949318299879298 0.949318299879298
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Rasgef1a ENSMUSG00000030134 0.630009345487522 0.731264730491952 0.731264730491952 0.731264730491952 0.675592754208279 0.731264730491952
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Pebp1 ENSMUSG00000032959 0.285581660641493 0.428372490962239 0.0941657923655824 0.282497377096747 0.580367267833894 0.580367267833894
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Dusp8 ENSMUSG00000037887 0.413364084032459 0.620046126048688 0.23839621310406 0.620046126048688 0.852819445432281 0.852819445432281
Kbtbd7 ENSMUSG00000043881 0.883904214304574 0.883904214304574 0.340772248229217 0.883904214304574 0.644136107337212 0.883904214304574
Spred2 ENSMUSG00000045671 0.776269634904547 0.80057783665013 0.585828497213068 0.80057783665013 0.80057783665013 0.80057783665013
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Paqr3 ENSMUSG00000055725 0.767133515203126 0.877668656828336 0.658299945831767 0.877668656828336 0.877668656828336 0.877668656828336
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Rapgef2 ENSMUSG00000062232 0.532650093135441 0.843568313157742 0.825066402286463 0.843568313157742 0.843568313157742 0.843568313157742
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Syngap1 ENSMUSG00000067629 0.49917993882886 0.865184883031372 0.728298167799716 0.865184883031372 0.865184883031372 0.865184883031372
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Rasal2 ENSMUSG00000070565 0.375974690480065 0.837354234576499 0.837354234576499 0.837354234576499 0.690066143506778 0.837354234576499

Sodium/Calcium exchangers

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Slc24a2 ENSMUSG00000037996 0.54200427865392 0.957631678136051 0.957631678136051 0.957631678136051 0.739133554902329 0.957631678136051
Slc24a4 ENSMUSG00000041771 0.817684759159923 0.817684759159923 0.474003798142661 0.817684759159923 0.608807387018037 0.817684759159923
Slc24a3 ENSMUSG00000063873 0.933948902380247 0.933948902380247 0.602016601246533 0.933948902380247 0.737091500661524 0.933948902380247
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

p75 NTR receptor-mediated signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Arhgef40 ENSMUSG00000004562 0.690115975723052 0.734258969628961 0.734258969628961 0.734258969628961 0.344799955228746 0.734258969628961
Sqstm1 ENSMUSG00000015837 0.548220980587803 0.822331470881704 0.0231457389756086 0.0694372169268258 0.974803078046978 0.974803078046978
Ywhae ENSMUSG00000020849 0.338772559987977 0.652664422283171 0.443381517540621 0.652664422283171 0.652664422283171 0.652664422283171
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Mapk8 ENSMUSG00000021936 0.342787832858501 0.548151789615794 0.365434526410529 0.548151789615794 0.908883586706986 0.908883586706986
Trio ENSMUSG00000022263 0.509511242550692 0.95593807589184 0.797512518800277 0.95593807589184 0.95593807589184 0.95593807589184
Itsn1 ENSMUSG00000022957 0.883886719873156 0.883886719873156 0.275034142500616 0.825102427501849 0.868324495200103 0.883886719873156
Tiam2 ENSMUSG00000023800 0.862097039059075 0.862097039059075 0.644127593764966 0.862097039059075 0.687109235269195 0.862097039059075
Fgd1 ENSMUSG00000025265 0.618850897072831 0.943366293933116 0.806686983694517 0.943366293933116 0.943366293933116 0.943366293933116
Arhgef9 ENSMUSG00000025656 0.618745738438739 0.98110185868436 0.788313677831522 0.98110185868436 0.98110185868436 0.98110185868436
Ngef ENSMUSG00000026259 0.516437236619428 0.852547986360803 0.672065880170334 0.852547986360803 0.852547986360803 0.852547986360803
Arhgef7 ENSMUSG00000031511 0.644132331828237 0.822001029757028 0.214011393745725 0.642034181237174 0.822001029757028 0.822001029757028
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Arhgef17 ENSMUSG00000032875 0.902626804113539 0.91513128746116 0.722365064561738 0.91513128746116 0.91513128746116 0.91513128746116
Mag ENSMUSG00000036634 0.434844107200354 0.652266160800532 0.317077958691326 0.652266160800532 0.735323530397301 0.735323530397301
Arhgef26 ENSMUSG00000036885 0.338744587725774 0.624404520746658 0.624404520746658 0.624404520746658 0.556253327919585 0.624404520746658
Plekhg5 ENSMUSG00000039713 0.779235921324691 0.779235921324691 0.749170734286215 0.779235921324691 0.519662892686707 0.779235921324691
Ngfrap1 ENSMUSG00000046432 0.946506652154109 0.946506652154109 0.613269482237527 0.946506652154109 0.849734644219946 0.946506652154109
Lingo1 ENSMUSG00000049556 0.645169115625323 0.949380268028432 0.657609224264133 0.949380268028432 0.949380268028432 0.949380268028432
Arhgef15 ENSMUSG00000052921 0.678504395758495 0.678504395758495 0.397719918405541 0.678504395758495 0.545704084312357 0.678504395758495
Arhgef33 ENSMUSG00000054901 0.724651036641199 0.951403625820301 0.951403625820301 0.951403625820301 0.762641987834789 0.951403625820301
Arhgef12 ENSMUSG00000059495 0.577591478934978 0.577591478934978 0.186038890901213 0.55811667270364 0.511996835816291 0.577591478934978
Kalrn ENSMUSG00000061751 0.880701115819307 0.943334779370904 0.535135820413651 0.943334779370904 0.943334779370904 0.943334779370904
Arhgef10 ENSMUSG00000071176 0.828121266477381 0.828121266477381 0.558870934116684 0.828121266477381 0.357078975694619 0.828121266477381

MAPK1/MAPK3 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Araf ENSMUSG00000001127 0.791442240628396 0.896377909496218 0.896377909496218 0.896377909496218 0.658368992471154 0.896377909496218
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Grin2d ENSMUSG00000002771 0.940085416826172 1 0.902523949046847 1 1 1
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Pea15a ENSMUSG00000013698 0.737241300937761 0.737241300937761 0.616073413108655 0.737241300937761 0.514625923838225 0.737241300937761
Psmd11 ENSMUSG00000017428 0.261308003324492 0.783924009973477 0.767211261815565 0.887021702252886 0.887021702252886 0.887021702252886
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Shc2 ENSMUSG00000020312 0.621382099191537 0.843438795450799 0.843438795450799 0.843438795450799 0.8066862854504 0.843438795450799
Psmc5 ENSMUSG00000020708 0.322975972173609 0.484463958260413 0.0226899522591512 0.0680698567774534 0.918264995578081 0.918264995578081
Nf1 ENSMUSG00000020716 0.371683595114246 0.690103142447791 0.690103142447791 0.690103142447791 0.669823684327671 0.690103142447791
Dlg4 ENSMUSG00000020886 0.604964681038937 0.692998126133769 0.646978722048408 0.692998126133769 0.692998126133769 0.692998126133769
Ppp2r5e ENSMUSG00000021051 0.27328621062012 0.81985863186036 0.849738175910655 0.849738175910655 0.71645413828763 0.849738175910655
Psmc1 ENSMUSG00000021178 0.303803557990059 0.455705336985088 0.0473364911568684 0.142009473470605 0.737100247931715 0.737100247931715
Shc3 ENSMUSG00000021448 0.955060281267071 0.955060281267071 0.947860333978269 0.955060281267071 0.730635945694304 0.955060281267071
Rasgrf2 ENSMUSG00000021708 0.887003417976647 0.887003417976647 0.7491259956385 0.887003417976647 0.852827943993641 0.887003417976647
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Camk2g ENSMUSG00000021820 0.484428673070367 0.66985387808963 0.467220263909899 0.66985387808963 0.66985387808963 0.66985387808963
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Nefl ENSMUSG00000022055 0.696922293658582 0.696922293658582 0.386145928077477 0.696922293658582 0.502412306571672 0.696922293658582
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Rbx1 ENSMUSG00000022400 0.481997668276524 0.890136873661692 0.890136873661692 0.890136873661692 0.76419865428903 0.890136873661692
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Dlg1 ENSMUSG00000022770 0.710594026728739 0.902624867689304 0.902624867689304 0.902624867689304 0.752165523959287 0.902624867689304
Frs3 ENSMUSG00000023266 0.877673101799547 0.974813738333914 0.974813738333914 0.974813738333914 0.71352514240849 0.974813738333914
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Ppp2r5b ENSMUSG00000024777 0.862129607166286 0.949649815783095 0.122181277937847 0.366543833813541 0.949649815783095 0.949649815783095
Arl2 ENSMUSG00000024944 0.126088068282607 0.189132102423911 0.0203930921867576 0.0611792765602728 0.244794130470382 0.244794130470382
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Cnksr2 ENSMUSG00000025658 0.899667566749859 0.899667566749859 0.690719928069651 0.899667566749859 0.782271280971245 0.899667566749859
Lypla1 ENSMUSG00000025903 0.474557263496955 0.711906776508762 0.474604517672508 0.711906776508762 0.9088641950551 0.9088641950551
Psmd1 ENSMUSG00000026229 0.80667720758842 0.80667720758842 0.00965305149467524 0.0289591544840257 0.315263318292765 0.472894977439147
Dab2ip ENSMUSG00000026883 0.908880355624594 0.908880355624594 0.352946406311928 0.908880355624594 0.701754095193645 0.908880355624594
Grin1 ENSMUSG00000026959 0.642864002617849 0.908851179294457 0.727115174466837 0.908851179294457 0.908851179294457 0.908851179294457
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Gfra4 ENSMUSG00000027316 0.342738850889216 0.822410862505053 0.548273908336702 0.822410862505053 0.887001324556299 0.887001324556299
Spred1 ENSMUSG00000027351 0.427124606838286 0.764198756499969 0.764198756499969 0.764198756499969 0.710594119338658 0.764198756499969
Rasal1 ENSMUSG00000029602 0.549673540060143 0.949318299879298 0.72963301255346 0.949318299879298 0.949318299879298 0.949318299879298
Tgfa ENSMUSG00000029999 0.896354202085325 0.949640717936953 0.949640717936953 0.949640717936953 0.734094865406341 0.949640717936953
Rasgef1a ENSMUSG00000030134 0.630009345487522 0.731264730491952 0.731264730491952 0.731264730491952 0.675592754208279 0.731264730491952
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Psma4 ENSMUSG00000032301 0.247975941111487 0.37196391166723 0.107458294298227 0.32237488289468 0.937074284143344 0.937074284143344
Rasgrf1 ENSMUSG00000032356 0.674639780040232 0.872033064586189 0.872033064586189 0.872033064586189 0.223371267599554 0.670113802798661
Mras ENSMUSG00000032470 0.7282646677435 0.940214434902219 0.716490260943039 0.940214434902219 0.940214434902219 0.940214434902219
Pebp1 ENSMUSG00000032959 0.285581660641493 0.428372490962239 0.0941657923655824 0.282497377096747 0.580367267833894 0.580367267833894
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Dusp8 ENSMUSG00000037887 0.413364084032459 0.620046126048688 0.23839621310406 0.620046126048688 0.852819445432281 0.852819445432281
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Kbtbd7 ENSMUSG00000043881 0.883904214304574 0.883904214304574 0.340772248229217 0.883904214304574 0.644136107337212 0.883904214304574
Spred2 ENSMUSG00000045671 0.776269634904547 0.80057783665013 0.585828497213068 0.80057783665013 0.80057783665013 0.80057783665013
Dlg2 ENSMUSG00000052572 0.849649310585556 0.889999652584818 0.889999652584818 0.889999652584818 0.566314811317713 0.889999652584818
Paqr3 ENSMUSG00000055725 0.767133515203126 0.877668656828336 0.658299945831767 0.877668656828336 0.877668656828336 0.877668656828336
Camk2b ENSMUSG00000057897 0.710586061943401 0.933939570804088 0.843546654329486 0.933939570804088 0.933939570804088 0.933939570804088
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Erbb4 ENSMUSG00000062209 0.547318866403199 0.654717627841397 0.61243928621552 0.654717627841397 0.654717627841397 0.654717627841397
Rapgef2 ENSMUSG00000062232 0.532650093135441 0.843568313157742 0.825066402286463 0.843568313157742 0.843568313157742 0.843568313157742
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Syngap1 ENSMUSG00000067629 0.49917993882886 0.865184883031372 0.728298167799716 0.865184883031372 0.865184883031372 0.865184883031372
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294
Psmb3 ENSMUSG00000069744 0.0555274707039526 0.16576112404045 0.745732271896758 0.745732271896758 0.110507416026967 0.16576112404045
Rasal2 ENSMUSG00000070565 0.375974690480065 0.837354234576499 0.837354234576499 0.837354234576499 0.690066143506778 0.837354234576499

Adenylate cyclase inhibitory pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.977956409661886 0.996849987604204 0.486802360984015 0.996849987604204 0.996849987604204 0.996849987604204
Adcy1 ENSMUSG00000020431 0.842528614131627 0.842528614131627 0.580492914948429 0.842528614131627 0.458952604996901 0.842528614131627
Adcy3 ENSMUSG00000020654 0.624420553487079 0.624420553487079 0.417814767824179 0.624420553487079 0.556157948908969 0.624420553487079
Adcy8 ENSMUSG00000022376 0.593459749138308 0.977630670246538 0.749206121507396 0.977630670246538 0.977630670246538 0.977630670246538
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gnal ENSMUSG00000024524 0.962225108172246 0.962225108172246 0.955886822011226 0.962225108172246 0.57732480709066 0.962225108172246
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362

Carboxyterminal post-translational modifications of tubulin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Ttll5 ENSMUSG00000012609 0.479406830553804 0.675519551901031 0.479532975588914 0.675519551901031 0.675519551901031 0.675519551901031
Ttll8 ENSMUSG00000022388 0.996753094767951 0.996753094767951 0.812898882393848 0.996753094767951 0.816691316273779 0.996753094767951
Ttll11 ENSMUSG00000026885 0.57212374802654 0.803516619643833 0.527053641075271 0.803516619643833 0.803516619643833 0.803516619643833
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Ttll13 ENSMUSG00000045467 0.0589883783663476 0.176965135099043 0.43554055241454 0.43554055241454 0.314160007902824 0.43554055241454
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Cell-cell junction organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh4 ENSMUSG00000000305 0.883898435194215 0.962222928866681 0.962222928866681 0.962222928866681 0.499291839744365 0.962222928866681
Cadm3 ENSMUSG00000005338 0.927671252776153 0.927671252776153 0.87456157244408 0.927671252776153 0.776261754900064 0.927671252776153
Pard6a ENSMUSG00000005699 0.540333259339338 0.540333259339338 0.17301166015541 0.519034980466231 0.48199026875276 0.540333259339338
Cdh10 ENSMUSG00000022321 0.910563390777357 0.935733972732352 0.541193371950511 0.935733972732352 0.935733972732352 0.935733972732352
Cdh2 ENSMUSG00000024304 0.899500180223969 0.899500180223969 0.548331065648196 0.899500180223969 0.695924443971456 0.899500180223969
Cdh11 ENSMUSG00000031673 0.569617241720249 0.899237671629727 0.943369721475633 0.943369721475633 0.599491781086484 0.899237671629727
Pvrl1 ENSMUSG00000032012 0.949652252269996 0.962228884180112 0.6216493344849 0.962228884180112 0.962228884180112 0.962228884180112
Cadm1 ENSMUSG00000032076 0.908882979006135 0.908882979006135 0.737236270265165 0.908882979006135 0.770227550031902 0.908882979006135
Cdh8 ENSMUSG00000036510 0.638429938693576 0.938515887904911 0.938515887904911 0.938515887904911 0.714648698741285 0.938515887904911
Cdh6 ENSMUSG00000039385 0.707816316063697 0.974436429017439 0.663709284627249 0.974436429017439 0.974436429017439 0.974436429017439
Sdk1 ENSMUSG00000039683 0.812789334038931 0.946482660387487 0.946482660387487 0.946482660387487 0.663976202157351 0.946482660387487
Sdk2 ENSMUSG00000041592 0.81496802580758 0.862127793351474 0.862127793351474 0.862127793351474 0.784331672671969 0.862127793351474
Pard6g ENSMUSG00000056214 0.215469229904447 0.646407689713342 0.644138180114681 0.655513687932582 0.655513687932582 0.655513687932582
Cdh24 ENSMUSG00000059674 0.445605303638133 0.788193710022696 0.788193710022696 0.788193710022696 0.563928501733135 0.788193710022696
Cadm2 ENSMUSG00000064115 0.642196774378791 0.866499519703549 0.866499519703549 0.866499519703549 0.657088842967535 0.866499519703549

Heparan sulfate/heparin (HS-GAG) metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Ndst3 ENSMUSG00000027977 0.660777196351522 0.857130114130428 0.857130114130428 0.857130114130428 0.636488911543187 0.857130114130428
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
Ids ENSMUSG00000035847 0.752170423358241 0.865239492021174 0.6901106916261 0.865239492021174 0.865239492021174 0.865239492021174
Hs2st1 ENSMUSG00000040151 0.899501307549021 0.899501307549021 0.332799292083218 0.899501307549021 0.776273209817288 0.899501307549021
Hs3st5 ENSMUSG00000044499 0.853996311088547 0.853996311088547 0.74123195090548 0.853996311088547 0.686076751806097 0.853996311088547
B3gat1 ENSMUSG00000045994 0.941590686501319 0.941590686501319 0.629538054037159 0.941590686501319 0.606171417556667 0.941590686501319
Hs3st2 ENSMUSG00000046321 0.838947706921784 0.996776192162678 0.996776192162678 0.996776192162678 0.967653626333733 0.996776192162678
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
Gpc6 ENSMUSG00000058571 0.849736318902451 0.849736318902451 0.474621122847807 0.71193168427171 0.344727157926739 0.71193168427171
Hs6st2 ENSMUSG00000062184 0.85887458944601 0.962178028086868 0.962178028086868 0.962178028086868 0.896335063174007 0.962178028086868
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689
Hs3st4 ENSMUSG00000078591 0.480944767352871 0.871889000176109 0.871889000176109 0.871889000176109 0.846807002613367 0.871889000176109

A tetrasaccharide linker sequence is required for GAG synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcan ENSMUSG00000004892 0.50231547790538 0.75347321685807 0.328440756793827 0.75347321685807 0.986721919132365 0.986721919132365
Gpc5 ENSMUSG00000022112 0.546890648679246 0.887599295210574 0.713316031366374 0.887599295210574 0.887599295210574 0.887599295210574
Sdc3 ENSMUSG00000025743 0.831214592590804 0.890124951172714 0.767184218463124 0.890124951172714 0.890124951172714 0.890124951172714
Bgn ENSMUSG00000031375 0.644039683252724 0.644039683252724 0.109118842818754 0.327356528456261 0.4480758162588 0.644039683252724
Cspg5 ENSMUSG00000032482 0.784914791487626 0.784914791487626 0.523954799509816 0.784914791487626 0.730289421535423 0.784914791487626
Cspg4 ENSMUSG00000032911 0.319081770736382 0.771924992622396 0.514616661748264 0.771924992622396 0.899498517071211 0.899498517071211
B3gat1 ENSMUSG00000045994 0.941590686501319 0.941590686501319 0.629538054037159 0.941590686501319 0.606171417556667 0.941590686501319
B3galt6 ENSMUSG00000050796 0.638480734405428 0.865235244385266 0.363327697326435 0.865235244385266 0.865235244385266 0.865235244385266
Gpc6 ENSMUSG00000058571 0.849736318902451 0.849736318902451 0.474621122847807 0.71193168427171 0.344727157926739 0.71193168427171
B3gat3 ENSMUSG00000071649 0.271558724909686 0.407338087364529 0.171917571305599 0.407338087364529 0.758178763241689 0.758178763241689

Adrenaline,noradrenaline inhibits insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Adcy5 ENSMUSG00000022840 0.772903057527803 0.93698328365658 0.580214236412823 0.93698328365658 0.93698328365658 0.93698328365658
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gnai1 ENSMUSG00000057614 0.927667620086362 0.927667620086362 0.545582754495406 0.927667620086362 0.8620863609682 0.927667620086362
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

NCAM signaling for neurite out-growth

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col6a1 ENSMUSG00000001119 0.64413255392032 0.825053542729307 0.815871801562435 0.825053542729307 0.825053542729307 0.825053542729307
Sptbn4 ENSMUSG00000011751 0.971462295802052 0.971462295802052 0.759220329458394 0.971462295802052 0.497439616768824 0.971462295802052
Col2a1 ENSMUSG00000022483 0.934860495046966 0.934860495046966 0.590621616867706 0.891697169896259 0.594464779930839 0.891697169896259
Ptk2 ENSMUSG00000022607 0.704704832096887 0.716469110256696 0.213997764379905 0.641993293139716 0.716469110256696 0.716469110256696
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
St8sia2 ENSMUSG00000025789 0.424675931893258 0.74496319565452 0.66720559161028 0.74496319565452 0.74496319565452 0.74496319565452
Col3a1 ENSMUSG00000026043 0.962229174919475 0.962229174919475 0.222919794712949 0.668759384138847 0.635672505496365 0.953508758244548
Ptpra ENSMUSG00000027303 0.968520072066281 0.968520072066281 0.599476605325835 0.940869820861954 0.627246547241303 0.940869820861954
Col9a3 ENSMUSG00000027570 0.445598407060097 0.608793960383343 0.608793960383343 0.608793960383343 0.202058912763573 0.606176738290719
Col4a2 ENSMUSG00000031503 0.984251264741664 0.984251264741664 0.044248817994663 0.132746453983989 0.883862041730424 0.984251264741664
Col6a3 ENSMUSG00000048126 0.890139725706414 0.890139725706414 0.216896844304325 0.475678360669622 0.317118907113081 0.475678360669622
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985
Sptbn2 ENSMUSG00000067889 0.775745313236853 0.899077893642294 0.899077893642294 0.899077893642294 0.799935303589272 0.899077893642294

Inwardly rectifying K+ channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Abcc8 ENSMUSG00000040136 0.917825989964953 0.917825989964953 0.527560844749489 0.917825989964953 0.671092266944401 0.917825989964953
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Kcnj14 ENSMUSG00000058743 0.861367135200491 0.993655940534168 0.527685400352532 0.993655940534168 0.993655940534168 0.993655940534168
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Ca2+ pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fzd3 ENSMUSG00000007989 0.553326734705599 0.901453267779014 0.792929655795697 0.901453267779014 0.901453267779014 0.901453267779014
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Wnt5a ENSMUSG00000021994 0.644038905321196 0.977956508119854 0.977956508119854 0.977956508119854 0.952773077423373 0.977956508119854
Camk2a ENSMUSG00000024617 0.779126728073991 0.952786687662668 0.952786687662668 0.952786687662668 0.952763411910628 0.952786687662668
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Ppp3ca ENSMUSG00000028161 0.785328217838219 0.791400548183424 0.302087911865875 0.791400548183424 0.791400548183424 0.791400548183424
Gnao1 ENSMUSG00000031748 0.710552096182477 0.859038403704427 0.788369570029828 0.859038403704427 0.859038403704427 0.859038403704427
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Ppp3r1 ENSMUSG00000033953 0.996851049600765 0.996851049600765 0.535237534418334 0.996851049600765 0.940226768683594 0.996851049600765
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Fzd2 ENSMUSG00000050288 0.494296960393072 0.741445440589608 0.413320422042367 0.741445440589608 0.918272798260785 0.918272798260785
Plcb1 ENSMUSG00000051177 0.484426718188429 0.962226650740842 0.962226650740842 0.962226650740842 0.803631828432092 0.962226650740842
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Signaling by FGFR1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Braf ENSMUSG00000002413 0.336756307137399 0.756687099134035 0.504458066089357 0.756687099134035 0.990553591782044 0.990553591782044
Ppp2r1a ENSMUSG00000007564 0.324943746761513 0.487415620142269 0.0773310136905452 0.231993041071636 0.572264728468875 0.572264728468875
Fgf10 ENSMUSG00000021732 0.996809582566527 0.996809582566527 0.782878208404071 0.996809582566527 0.559268423462592 0.996809582566527
Fgf9 ENSMUSG00000021974 0.561375891551696 0.704584629424288 0.6697644180408 0.704584629424288 0.704584629424288 0.704584629424288
Fgf17 ENSMUSG00000022101 0.663168973299807 0.696956631784244 0.354672489966722 0.696956631784244 0.696956631784244 0.696956631784244
Spry2 ENSMUSG00000022114 0.271548083179129 0.55444832078951 0.369632213859673 0.55444832078951 0.921402702786057 0.921402702786057
Frs3 ENSMUSG00000023266 0.877673101799547 0.974813738333914 0.974813738333914 0.974813738333914 0.71352514240849 0.974813738333914
Hras ENSMUSG00000025499 0.118323185762317 0.177484778643475 0.0156510182338144 0.0469530547014431 0.915124422415493 0.915124422415493
Spred1 ENSMUSG00000027351 0.427124606838286 0.764198756499969 0.764198756499969 0.764198756499969 0.710594119338658 0.764198756499969
Fgfr1 ENSMUSG00000031565 0.949652583470168 0.949652583470168 0.912008434688935 0.949652583470168 0.785362363800007 0.949652583470168
Ptpn11 ENSMUSG00000043733 0.93708715091726 0.968516112479348 0.10830738456926 0.324922153707781 0.968516112479348 0.968516112479348
Spred2 ENSMUSG00000045671 0.776269634904547 0.80057783665013 0.585828497213068 0.80057783665013 0.80057783665013 0.80057783665013
Flrt2 ENSMUSG00000047414 0.319084319486251 0.764165556511343 0.764165556511343 0.764165556511343 0.517141940071175 0.764165556511343
Flrt3 ENSMUSG00000051379 0.933921256765025 0.933921256765025 0.481852855150116 0.866156863556788 0.577437909037859 0.866156863556788
Fgf18 ENSMUSG00000057967 0.552946463945197 0.654986124710169 0.278237993131116 0.654986124710169 0.654986124710169 0.654986124710169
Mapk1 ENSMUSG00000063358 0.779285739065985 0.779285739065985 0.450522900414852 0.779285739065985 0.649816908079683 0.779285739065985

HDL assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Bmp1 ENSMUSG00000022098 0.737225020862538 0.737225020862538 0.580371415231663 0.737225020862538 0.268116819523234 0.737225020862538
A2m ENSMUSG00000030111 0.9326152276123 0.9326152276123 0.585537805984835 0.878306708977253 0.553750045386439 0.878306708977253
Zdhhc8 ENSMUSG00000060166 0.761185380208224 0.99685122678873 0.84665661450784 0.99685122678873 0.99685122678873 0.99685122678873

Post-translational modification: synthesis of GPI-anchored proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pigyl ENSMUSG00000010607 0.358727531785005 0.538091297677507 0.764129196797934 0.764129196797934 0.222580182002804 0.538091297677507
Ly6h ENSMUSG00000022577 0.711369310463879 0.939277981388271 0.939277981388271 0.939277981388271 0.850417716757855 0.939277981388271
Gpihbp1 ENSMUSG00000022579 0.791033639942828 0.791033639942828 0.781968601666039 0.791033639942828 0.518860917248302 0.791033639942828
Mfi2 ENSMUSG00000022780 0.461844356649342 0.655752348920256 0.589207759441026 0.655752348920256 0.655752348920256 0.655752348920256
Lypd1 ENSMUSG00000026344 0.685426184428996 0.860945288537717 0.860945288537717 0.860945288537717 0.614267485892732 0.860945288537717
Lypd6b ENSMUSG00000026765 0.861698597668735 0.861698597668735 0.855490481609002 0.861698597668735 0.582627112951854 0.861698597668735
Cntn3 ENSMUSG00000030075 0.64957903873346 0.850347979474873 0.687026409852247 0.850347979474873 0.850347979474873 0.850347979474873
Art4 ENSMUSG00000030217 0.805499233154367 0.805499233154367 0.663336776904067 0.805499233154367 0.735942253480688 0.805499233154367
Thy1 ENSMUSG00000032011 0.635624702923332 0.758161126647488 0.758161126647488 0.758161126647488 0.615989173542166 0.758161126647488
Mdga2 ENSMUSG00000034912 0.433991287285244 0.650986930927866 0.287439172785827 0.650986930927866 0.669798585976263 0.669798585976263
Otoa ENSMUSG00000034990 0.776589172299155 0.776589172299155 0.60368792614401 0.776589172299155 0.460559904961678 0.776589172299155
Tecta ENSMUSG00000037705 0.43117899067466 0.971534571952684 0.971534571952684 0.971534571952684 0.822519902982581 0.971534571952684
Nrn1 ENSMUSG00000039114 0.666978565979097 0.758181353455148 0.731283371316096 0.758181353455148 0.758181353455148 0.758181353455148
Cntn5 ENSMUSG00000039488 0.733912892360141 0.733912892360141 0.596609458633488 0.733912892360141 0.581435339718468 0.733912892360141
Negr1 ENSMUSG00000040037 0.607553003052472 0.943350663269467 0.846628148231004 0.943350663269467 0.943350663269467 0.943350663269467
Mdga1 ENSMUSG00000043557 0.761105718817176 0.959080336129702 0.883875387397894 0.959080336129702 0.959080336129702 0.959080336129702
Nrn1l ENSMUSG00000044287 0.312331415351241 0.664910277526957 0.92741059585437 0.92741059585437 0.443273518351304 0.664910277526957
Pigz ENSMUSG00000045625 0.712774224201925 0.712774224201925 0.695374522001152 0.712774224201925 0.267583903235999 0.712774224201925
Sprn ENSMUSG00000045733 0.642387399969371 0.963581099954057 0.968306200226156 0.968306200226156 0.603815440103056 0.963581099954057
Cd109 ENSMUSG00000046186 0.734980237835777 0.955569859710824 0.955569859710824 0.955569859710824 0.445423810511397 0.955569859710824
Rtn4rl2 ENSMUSG00000050896 0.58216583650687 0.911850132285419 0.911850132285419 0.911850132285419 0.852544391181176 0.911850132285419
Ntng1 ENSMUSG00000059857 0.926534171334259 0.926534171334259 0.910073513352151 0.926534171334259 0.850476861484157 0.926534171334259
Ntm ENSMUSG00000059974 0.915000641901984 0.915000641901984 0.746106169393107 0.915000641901984 0.736889419672299 0.915000641901984
Lsamp ENSMUSG00000061080 0.522439575655309 0.885492758419095 0.885492758419095 0.885492758419095 0.830943631778882 0.885492758419095
Opcml ENSMUSG00000062257 0.453475584020108 0.817726523624295 0.76630629092217 0.817726523624295 0.817726523624295 0.817726523624295

Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Gja1 ENSMUSG00000050953 0.88701856986789 0.88701856986789 0.494408517230221 0.88701856986789 0.707647157078212 0.88701856986789
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

EPH-ephrin mediated repulsion of cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Efna2 ENSMUSG00000003070 0.936583512400363 0.936583512400363 0.475645144496735 0.935900462512868 0.623933641675245 0.935900462512868
Efnb3 ENSMUSG00000003934 0.800522966745301 0.800522966745301 0.666458074418661 0.800522966745301 0.736851218580287 0.800522966745301
Ephb3 ENSMUSG00000005958 0.183431219200921 0.550293657602762 0.627226075905245 0.755174853692895 0.755174853692895 0.755174853692895
Epha4 ENSMUSG00000026235 0.719072804176109 0.92125741596729 0.92125741596729 0.92125741596729 0.574584953961931 0.92125741596729
Efna3 ENSMUSG00000028039 0.929926815544222 0.929926815544222 0.633020914457114 0.929926815544222 0.847560096431927 0.929926815544222
Epha7 ENSMUSG00000028289 0.35555382798597 0.533330741978955 0.892523935469897 0.892523935469897 0.30924656802498 0.533330741978955
Epha8 ENSMUSG00000028661 0.871602289088459 0.871602289088459 0.633449152957083 0.871602289088459 0.389920350254007 0.871602289088459
Epha5 ENSMUSG00000029245 0.558347297454362 0.812065592587143 0.304633418394484 0.812065592587143 0.812065592587143 0.812065592587143
Ephb4 ENSMUSG00000029710 0.289141625293623 0.433712437940435 0.256246177713627 0.433712437940435 0.828122627229947 0.828122627229947
Ephb6 ENSMUSG00000029869 0.655380113285498 0.902332597960477 0.902332597960477 0.902332597960477 0.480544117616069 0.902332597960477
Aph1b ENSMUSG00000032375 0.496920275035369 0.846393059629759 0.977961589221028 0.977961589221028 0.564262039753173 0.846393059629759
Ephb1 ENSMUSG00000032537 0.892973586486823 0.962196544970809 0.291449982519107 0.874349947557322 0.962196544970809 0.962196544970809
Efna5 ENSMUSG00000048915 0.779212682332545 0.779212682332545 0.610218927069066 0.779212682332545 0.658120357777135 0.779212682332545

HSP90 chaperone cycle for steroid hormone receptors (SHR)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Dynll2 ENSMUSG00000020483 0.283871065373224 0.425806598059836 0.0438431281822509 0.131529384546753 0.764191524748187 0.764191524748187
Actr10 ENSMUSG00000021076 0.669849228095005 0.695941807023691 0.695941807023691 0.695941807023691 0.535250403728396 0.695941807023691
Stip1 ENSMUSG00000024966 0.363309267041545 0.544963900562317 0.165599575958675 0.496798727876025 0.803623622830469 0.803623622830469
Dctn3 ENSMUSG00000028447 0.1847428427728 0.2771142641592 0.0135232125409904 0.0405696376229711 0.532651238456293 0.532651238456293
Dync1i1 ENSMUSG00000029757 0.812594681821339 0.927644345002271 0.927644345002271 0.927644345002271 0.666543997730284 0.927644345002271
Dnaja2 ENSMUSG00000031701 0.666898471046475 0.821897650885822 0.0917061551886996 0.275118465566099 0.821897650885822 0.821897650885822
Pgr ENSMUSG00000031870 0.547963212007977 0.618731259389758 0.618731259389758 0.618731259389758 0.567133180230395 0.618731259389758
Dync1li2 ENSMUSG00000035770 0.535252137809611 0.933945421899857 0.831224283473137 0.933945421899857 0.933945421899857 0.933945421899857
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Ar ENSMUSG00000046532 0.391159671868941 0.798934797899769 0.532623198599846 0.798934797899769 0.818931220190683 0.818931220190683
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Hspa2 ENSMUSG00000059970 0.594008065071973 0.731292632575019 0.266394520925093 0.731292632575019 0.731292632575019 0.731292632575019
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Effects of PIP2 hydrolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dgke ENSMUSG00000000276 0.438701356587272 0.93393028681949 0.93393028681949 0.93393028681949 0.641220236857371 0.93393028681949
Dgkg ENSMUSG00000022861 0.833650333926293 0.839891174827249 0.839891174827249 0.839891174827249 0.721688536261811 0.839891174827249
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Mgll ENSMUSG00000033174 0.574971563922836 0.678474080357625 0.0332923773738217 0.099877132121465 0.678474080357625 0.678474080357625
Dgkh ENSMUSG00000034731 0.388421388936085 0.869870998884137 0.579913999256091 0.869870998884137 0.971642477410861 0.971642477410861
Dagla ENSMUSG00000035735 0.716365652254505 0.921367628058699 0.886972832447325 0.921367628058699 0.921367628058699 0.921367628058699
Dgkb ENSMUSG00000036095 0.530837257895833 0.958816829108309 0.958816829108309 0.958816829108309 0.780706242274577 0.958816829108309
Dgki ENSMUSG00000038665 0.534194562344775 0.923422221300899 0.83838067754833 0.923422221300899 0.923422221300899 0.923422221300899
Prkce ENSMUSG00000045038 0.946501605821244 0.946501605821244 0.615992802977437 0.946501605821244 0.82504425671217 0.946501605821244

BBSome-mediated cargo-targeting to cilium

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bbs1 ENSMUSG00000006464 0.535252731043498 0.535252731043498 0.486936148072312 0.535252731043498 0.469722306572126 0.535252731043498
Ttc8 ENSMUSG00000021013 0.719390438614795 0.921389481967084 0.921389481967084 0.921389481967084 0.607740786546488 0.921389481967084
Arl6 ENSMUSG00000022722 0.566864459187481 0.949646031228839 0.949646031228839 0.949646031228839 0.883901627326227 0.949646031228839
Bbs4 ENSMUSG00000025235 0.809736044283554 0.874560766809878 0.436365037051699 0.874560766809878 0.874560766809878 0.874560766809878
Lztfl1 ENSMUSG00000025245 0.241493453021677 0.362240179532515 0.239981407729023 0.362240179532515 0.7581550549986 0.7581550549986
Bbs2 ENSMUSG00000031755 0.743202922243233 0.743202922243233 0.690115844444411 0.743202922243233 0.512070547999815 0.743202922243233
Bbs7 ENSMUSG00000037325 0.455256964026811 0.785352682969664 0.785352682969664 0.785352682969664 0.627220688152427 0.785352682969664
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Bbs5 ENSMUSG00000063145 0.644141326225708 0.927613096268093 0.899417726942463 0.927613096268093 0.927613096268093 0.927613096268093

Reduction of cytosolic Ca++ levels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

GPCR ligand binding

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grm3 ENSMUSG00000003974 0.908579564055764 0.960288948778942 0.79571168481903 0.960288948778942 0.960288948778942 0.960288948778942
Sst ENSMUSG00000004366 0.715876360137629 0.926467819132948 0.888311656088167 0.926467819132948 0.926467819132948 0.926467819132948
Vipr2 ENSMUSG00000011171 0.81442795927062 0.81442795927062 0.274336900623371 0.670413060812143 0.446942040541429 0.670413060812143
Adora2b ENSMUSG00000018500 0.837350848364286 0.837350848364286 0.479496262271254 0.837350848364286 0.800519563145664 0.837350848364286
Ccl6 ENSMUSG00000018927 0.971654522167911 0.971654522167911 0.78821263178141 0.971654522167911 0.87446006544789 0.971654522167911
Ccl9 ENSMUSG00000019122 0.868342576542606 0.868342576542606 0.638411734452223 0.868342576542606 0.755133023615109 0.868342576542606
Grm1 ENSMUSG00000019828 0.435817571371699 0.968145858068542 0.977386134554169 0.977386134554169 0.645430572045694 0.968145858068542
Nmbr ENSMUSG00000019865 0.592774912955548 0.944018380658151 0.754309607011397 0.944018380658151 0.944018380658151 0.944018380658151
Ntsr2 ENSMUSG00000020591 1 1 0.958561123765929 1 0.933224198368138 1
Tshr ENSMUSG00000020963 0.749652680700576 0.917286863864632 0.00541113501137084 0.0162334050341125 0.917286863864632 0.917286863864632
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Drd1a ENSMUSG00000021478 0.858920911141562 0.858920911141562 0.84527631259123 0.858920911141562 0.847625769604738 0.858920911141562
Ednrb ENSMUSG00000022122 0.0715275231264876 0.214582569379463 0.455223418249381 0.455223418249381 0.395534064897452 0.455223418249381
C3 ENSMUSG00000024164 0.675614763347999 0.97166728513593 0.97166728513593 0.97166728513593 0.893257765188331 0.97166728513593
Grm8 ENSMUSG00000024211 0.581459279843197 0.863797416908078 0.863797416908078 0.863797416908078 0.746413291246183 0.863797416908078
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Grp ENSMUSG00000024517 0.722584098475009 0.990287032276337 0.990287032276337 0.990287032276337 0.906223610168785 0.990287032276337
Htr7 ENSMUSG00000024798 0.71632417058308 0.865139469179896 0.865139469179896 0.865139469179896 0.7821207757961 0.865139469179896
Tac2 ENSMUSG00000025400 0.783864107879587 0.783864107879587 0.362610864480765 0.708757538619127 0.472505025746085 0.708757538619127
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Gpr37l1 ENSMUSG00000026424 0.803430731628327 0.852391434517777 0.430344704615273 0.852391434517777 0.852391434517777 0.852391434517777
Opn3 ENSMUSG00000026525 0.7882032871944 0.996845708704885 0.430664212814841 0.996845708704885 0.996845708704885 0.996845708704885
Gnas ENSMUSG00000027523 0.599490965229092 0.899236447843638 0.0865570759124397 0.259671227737319 0.905746850677186 0.905746850677186
Oprl1 ENSMUSG00000027584 0.933329245678453 0.936720060465393 0.936720060465393 0.936720060465393 0.471739845590983 0.936720060465393
Tacr3 ENSMUSG00000028172 0.86353619522057 0.960980457908582 0.830458999836668 0.960980457908582 0.960980457908582 0.960980457908582
Hcrtr1 ENSMUSG00000028778 0.776739267290508 0.776739267290508 0.483111972157679 0.776739267290508 0.534372493672934 0.776739267290508
Adcyap1r1 ENSMUSG00000029778 0.815841204611913 0.82505533055045 0.82505533055045 0.82505533055045 0.543081687242773 0.82505533055045
Npy ENSMUSG00000029819 0.69336514703811 0.908358346124833 0.908358346124833 0.908358346124833 0.867587148683731 0.908358346124833
Tacr1 ENSMUSG00000030043 0.874952532257405 0.990351663867859 0.990351663867859 0.990351663867859 0.910104110536735 0.990351663867859
Rho ENSMUSG00000030324 0.757266463676936 0.836801121052075 0.836801121052075 0.836801121052075 0.378777142477677 0.836801121052075
Gipr ENSMUSG00000030406 0.818861357220811 0.910855665291448 0.910855665291448 0.910855665291448 0.840617980437171 0.910855665291448
Calca ENSMUSG00000030669 0.588254249512147 0.83228400266544 0.5840247548685 0.83228400266544 0.83228400266544 0.83228400266544
Adm ENSMUSG00000030790 0.108342584744364 0.325027754233093 0.95279451230384 0.95279451230384 0.282037973830839 0.423056960746258
Grpr ENSMUSG00000031364 0.594100327338923 0.818349668482925 0.513345501338216 0.818349668482925 0.818349668482925 0.818349668482925
Cx3cl1 ENSMUSG00000031778 0.95593673909406 0.95593673909406 0.561519337590622 0.95593673909406 0.877665688727172 0.95593673909406
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Hcrtr2 ENSMUSG00000032360 0.964816963971967 0.977590851896125 0.658466283082889 0.977590851896125 0.977590851896125 0.977590851896125
Cck ENSMUSG00000032532 0.848947018692305 1 0.653741884609598 1 1 1
Chrm1 ENSMUSG00000032773 0.932299523594956 0.932299523594956 0.881202389046309 0.932299523594956 0.746785362016616 0.932299523594956
Adra2a ENSMUSG00000033717 0.644446283881771 0.942751546995606 0.942751546995606 0.942751546995606 0.873478514309384 0.942751546995606
Rxfp1 ENSMUSG00000034009 0.867314449376788 0.867314449376788 0.504899795098141 0.867314449376788 0.741385117263809 0.867314449376788
Ramp1 ENSMUSG00000034353 0.315244609202721 0.782329854444019 0.65548419813422 0.782329854444019 0.782329854444019 0.782329854444019
Htr2a ENSMUSG00000034997 0.65581291592056 0.970791750766453 0.970791750766453 0.970791750766453 0.940885159381972 0.970791750766453
Adrb1 ENSMUSG00000035283 0.880764668424434 0.880764668424434 0.649774474794178 0.880764668424434 0.834300128626595 0.880764668424434
Ccl12 ENSMUSG00000035352 0.849294173138853 0.87111409750574 0.81558405325349 0.87111409750574 0.87111409750574 0.87111409750574
Sstr1 ENSMUSG00000035431 0.406238592066445 0.964057292265133 0.964057292265133 0.964057292265133 0.783863340301641 0.964057292265133
Kiss1r ENSMUSG00000035773 0.692593027585027 0.692593027585027 0.66927584815228 0.692593027585027 0.566498128060593 0.692593027585027
Npy1r ENSMUSG00000036437 0.404299171034672 0.952738532723292 0.952738532723292 0.952738532723292 0.911889505521477 0.952738532723292
Apln ENSMUSG00000037010 0.75810612490527 0.75810612490527 0.661208628433793 0.75810612490527 0.675573817300198 0.75810612490527
Hrh3 ENSMUSG00000039059 0.561691926760614 0.924539440001392 0.924539440001392 0.924539440001392 0.750233152811516 0.924539440001392
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Gpr37 ENSMUSG00000039904 0.966888860531268 0.966888860531268 0.728518758974939 0.966888860531268 0.655532904753802 0.966888860531268
Chrm4 ENSMUSG00000040495 0.713559919137436 0.713559919137436 0.653668107827576 0.713559919137436 0.639519564436859 0.713559919137436
C3ar1 ENSMUSG00000040552 0.000211666510129739 0.000634999530389216 0.478720811527367 0.71808121729105 0.864363428489762 0.864363428489762
Ramp3 ENSMUSG00000041046 0.698743119896013 0.825056637739825 0.183309696073174 0.549929088219521 0.825056637739825 0.825056637739825
Adora1 ENSMUSG00000042429 0.713334164030766 0.965365256020669 0.824970993397989 0.965365256020669 0.965365256020669 0.965365256020669
Ccrl2 ENSMUSG00000043953 0.737108824504718 0.737108824504718 0.734231892352291 0.737108824504718 0.358976102789146 0.737108824504718
Cnr1 ENSMUSG00000044288 0.745786054078664 0.949484405913581 0.793882327064725 0.949484405913581 0.949484405913581 0.949484405913581
D3Bwg0562e ENSMUSG00000044667 0.729308876843026 0.948912844531608 0.948912844531608 0.948912844531608 0.87637346562311 0.948912844531608
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
S1pr5 ENSMUSG00000045087 0.581310188081916 0.940038730735353 0.830636858120185 0.940038730735353 0.940038730735353 0.940038730735353
Adra2c ENSMUSG00000045318 0.394366372153552 0.591549558230328 0.206027859764988 0.591549558230328 0.688768008546255 0.688768008546255
Penk ENSMUSG00000045573 0.803570970818424 0.959069192685323 0.877609538741843 0.959069192685323 0.959069192685323 0.959069192685323
Chrm3 ENSMUSG00000046159 0.569021667449715 0.587954814132193 0.587954814132193 0.587954814132193 0.577577095485569 0.587954814132193
Sstr2 ENSMUSG00000047904 0.851796321705487 0.905493028238661 0.905493028238661 0.905493028238661 0.723393049137971 0.905493028238661
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
F2r ENSMUSG00000048376 0.580404039979417 0.580404039979417 0.441066914087247 0.580404039979417 0.183408276761207 0.550224830283621
Oxtr ENSMUSG00000049112 0.831742501905765 0.831742501905765 0.826425844353388 0.831742501905765 0.614393062117814 0.831742501905765
Agtr1a ENSMUSG00000049115 0.728217618478477 0.924514170482059 0.322991259966129 0.924514170482059 0.924514170482059 0.924514170482059
Htr1b ENSMUSG00000049511 0.936295840527735 0.971386135198569 0.971386135198569 0.971386135198569 0.781319656986589 0.971386135198569
Grm5 ENSMUSG00000049583 0.283290335716381 0.849871007149144 0.715021442534369 0.986418932465133 0.986418932465133 0.986418932465133
Lpar4 ENSMUSG00000049929 0.649678340446368 0.974517510669552 0.984253359649956 0.984253359649956 0.401966594560456 0.974517510669552
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Oprd1 ENSMUSG00000050511 0.843607928113184 0.887326964308433 0.802723620517678 0.887326964308433 0.887326964308433 0.887326964308433
Prokr2 ENSMUSG00000050558 0.980370352060819 0.980370352060819 0.764119976094218 0.980370352060819 0.882236886919263 0.980370352060819
Gpr17 ENSMUSG00000052229 0.841592903524789 0.841592903524789 0.735388479275896 0.841592903524789 0.818830393220439 0.841592903524789
Hrh1 ENSMUSG00000053004 0.870944697313483 0.870944697313483 0.578058362087012 0.870944697313483 0.64722556831022 0.870944697313483
Gper1 ENSMUSG00000053647 0.340734658300866 0.5111019874513 0.305493224887898 0.5111019874513 0.580124431812303 0.580124431812303
Grm7 ENSMUSG00000056755 0.858717824204382 0.977471956051544 0.625073995050131 0.977471956051544 0.977471956051544 0.977471956051544
Tac1 ENSMUSG00000061762 0.917404416369368 0.917404416369368 0.761517449025984 0.917404416369368 0.737667215472087 0.917404416369368
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155
Gm13306 ENSMUSG00000073877 0.316304878030798 0.554270327907138 0.727562091395151 0.727562091395151 0.369513551938092 0.554270327907138

G protein gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Activation of G protein gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gng4 ENSMUSG00000021303 0.670442186530672 0.828891623591614 0.758744094756286 0.828891623591614 0.828891623591614 0.828891623591614
Gabbr1 ENSMUSG00000024462 0.767197223678733 0.959081801454676 0.959081801454676 0.959081801454676 0.491916608428109 0.959081801454676
Gng13 ENSMUSG00000025739 0.621826760804494 0.910289124430798 0.727777576626169 0.910289124430798 0.910289124430798 0.910289124430798
Kcnj3 ENSMUSG00000026824 0.564914328064943 0.847371492097415 0.498867148016485 0.847371492097415 0.920962843273059 0.920962843273059
Gnb5 ENSMUSG00000032192 0.580405774676071 0.870608662014106 0.556267673638167 0.870608662014106 0.930812474173663 0.930812474173663
Kcnj9 ENSMUSG00000038026 0.974743191626452 0.974743191626452 0.742232599569064 0.974743191626452 0.929708710426385 0.974743191626452
Gabbr2 ENSMUSG00000039809 0.925727401919855 0.925727401919855 0.684305248963215 0.925727401919855 0.85914911392925 0.925727401919855
Kcnj10 ENSMUSG00000044708 0.773174975497142 0.993701351230168 0.7193497417441 0.993701351230168 0.993701351230168 0.993701351230168
Gng7 ENSMUSG00000048240 0.481663888433525 0.722495832650287 0.301794849904631 0.722495832650287 0.785162214352997 0.785162214352997
Gng5 ENSMUSG00000068523 0.588479373635212 0.862126406268316 0.644125335715245 0.862126406268316 0.862126406268316 0.862126406268316
Gng3 ENSMUSG00000071658 0.858689825833898 0.943231776372155 0.429891949516125 0.943231776372155 0.943231776372155 0.943231776372155

PKA activation in glucagon signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477

CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

CaMK IV-mediated phosphorylation of CREB

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Camkk1 ENSMUSG00000020785 0.937003294564886 0.937003294564886 0.713194447504243 0.937003294564886 0.375609817407471 0.937003294564886
Camkk2 ENSMUSG00000029471 0.532429394291184 0.574925400529296 0.408865586559088 0.574925400529296 0.574925400529296 0.574925400529296
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188

CREB1 phosphorylation through the activation of Adenylate Cyclase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkacb ENSMUSG00000005034 0.996849848223171 0.996849848223171 0.404391039575032 0.996849848223171 0.828074243970105 0.996849848223171
Prkaca ENSMUSG00000005469 0.431715159187803 0.647572738781705 0.0654104413089323 0.196231323926797 0.767202551400073 0.767202551400073
Prkar1a ENSMUSG00000020612 0.716473261982248 0.840461380124911 0.269827323393071 0.809481970179212 0.840461380124911 0.840461380124911
Prkar1b ENSMUSG00000025855 0.474519391763333 0.711779087645 0.386663735659615 0.711779087645 0.959080463952477 0.959080463952477

Tachykinin receptors bind tachykinins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tac2 ENSMUSG00000025400 0.783864107879587 0.783864107879587 0.362610864480765 0.708757538619127 0.472505025746085 0.708757538619127
Tacr3 ENSMUSG00000028172 0.86353619522057 0.960980457908582 0.830458999836668 0.960980457908582 0.960980457908582 0.960980457908582
Tacr1 ENSMUSG00000030043 0.874952532257405 0.990351663867859 0.990351663867859 0.990351663867859 0.910104110536735 0.990351663867859
Tac1 ENSMUSG00000061762 0.917404416369368 0.917404416369368 0.761517449025984 0.917404416369368 0.737667215472087 0.917404416369368

Platelet calcium homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Atp2b1 ENSMUSG00000019943 0.251251573307962 0.753754719923886 0.797523203464361 0.797523203464361 0.770152473676631 0.797523203464361
P2rx3 ENSMUSG00000027071 0.457675632452868 0.457675632452868 0.427068943705184 0.457675632452868 0.361213091154555 0.457675632452868
Itpr1 ENSMUSG00000030102 0.661228645664383 0.831212661640889 0.413413747784192 0.831212661640889 0.831212661640889 0.831212661640889
Atp2b2 ENSMUSG00000030302 0.9558798864846 0.9558798864846 0.724858285114954 0.9558798864846 0.610075835605225 0.9558798864846
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Atp2b3 ENSMUSG00000031376 0.75915964137692 0.987178207114337 0.987178207114337 0.987178207114337 0.875602611650513 0.987178207114337
Trpc6 ENSMUSG00000031997 0.996814264475394 0.996814264475394 0.78658940620741 0.996814264475394 0.926949541164742 0.996814264475394
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Transport of connexons to the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tubb6 ENSMUSG00000001473 0.666944016813025 0.666944016813025 0.393305603686983 0.589958405530475 0.203884805409493 0.589958405530475
Tuba1c ENSMUSG00000043091 0.981104625657567 0.981104625657567 0.550912391052476 0.981104625657567 0.883854748620768 0.981104625657567
Tubb2b ENSMUSG00000045136 0.693023060137088 0.693023060137088 0.574983187899649 0.693023060137088 0.661232158961782 0.693023060137088
Gja1 ENSMUSG00000050953 0.88701856986789 0.88701856986789 0.494408517230221 0.88701856986789 0.707647157078212 0.88701856986789
Tubb2a ENSMUSG00000058672 0.965370288821198 0.965370288821198 0.319048688772338 0.633794174090819 0.422529449393879 0.633794174090819
Tubb3 ENSMUSG00000062380 0.809709217129473 0.846625661118874 0.779277550519025 0.846625661118874 0.846625661118874 0.846625661118874
Tubb4a ENSMUSG00000062591 0.968506416252794 0.968506416252794 0.300209608837592 0.900628826512777 0.737123541420873 0.968506416252794
Tuba1a ENSMUSG00000072235 0.469626976829964 0.681364234452516 0.681364234452516 0.681364234452516 0.629966728581847 0.681364234452516

Transport of inorganic cations/anions and amino acids/oligopeptides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc25a18 ENSMUSG00000004902 0.835716796133805 0.856155552714375 0.856155552714375 0.856155552714375 0.307159790391501 0.856155552714375
Slc1a2 ENSMUSG00000005089 0.862132076278121 0.921373951455365 0.90572594460177 0.921373951455365 0.921373951455365 0.921373951455365
Slc1a6 ENSMUSG00000005357 0.874617772289123 0.874617772289123 0.678900745992563 0.874617772289123 0.835080831306818 0.874617772289123
Slc1a3 ENSMUSG00000005360 0.80969362006481 0.8651964754681 0.8651964754681 0.8651964754681 0.391156066012029 0.8651964754681
Slc4a3 ENSMUSG00000006576 0.955938803215994 0.955938803215994 0.632841118828259 0.949261678242388 0.632816340199223 0.949261678242388
Slc9a5 ENSMUSG00000014786 0.64122605385598 0.785310179389001 0.588371391923136 0.785310179389001 0.785310179389001 0.785310179389001
Slc12a5 ENSMUSG00000017740 0.996851063664395 0.996851063664395 0.251175722824672 0.753527168474017 0.599246759979626 0.898870139969439
Slc12a7 ENSMUSG00000017756 0.585810066458965 0.785352682969664 0.324905585919778 0.785352682969664 0.785352682969664 0.785352682969664
Calm3 ENSMUSG00000019370 0.933951389151844 0.933951389151844 0.773246164604135 0.933951389151844 0.800580278137264 0.933951389151844
Slc16a10 ENSMUSG00000019838 0.509107823991209 0.763661735986814 0.257769197059797 0.763661735986814 0.852668566552395 0.852668566552395
Slc1a4 ENSMUSG00000020142 0.887001249341426 0.887001249341426 0.509504424388217 0.887001249341426 0.638478258743037 0.887001249341426
Slc25a29 ENSMUSG00000021265 0.055521500843306 0.166564502529918 0.298122597879254 0.447183896818882 0.791420714790527 0.791420714790527
Slc9a4 ENSMUSG00000026065 0.816135961884783 0.816135961884783 0.499885151109367 0.816135961884783 0.766215783643848 0.816135961884783
Slc4a10 ENSMUSG00000026904 0.652785982436998 0.825971070312211 0.825971070312211 0.825971070312211 0.717883814347885 0.825971070312211
Slc7a11 ENSMUSG00000027737 0.390963664496459 0.930732216776983 0.930732216776983 0.930732216776983 0.622668968095726 0.930732216776983
Slc8a2 ENSMUSG00000030376 0.706820040579845 0.962192285960256 0.668389307795618 0.962192285960256 0.962192285960256 0.962192285960256
Slc7a10 ENSMUSG00000030495 0.617216518815915 0.624619381552089 0.624619381552089 0.624619381552089 0.400163987845447 0.624619381552089
Slc7a3 ENSMUSG00000031297 0.864966665985726 0.864966665985726 0.858371595970544 0.864966665985726 0.790441108300969 0.864966665985726
Calm2 ENSMUSG00000036438 0.269827806747655 0.423136678654263 0.282091119102842 0.423136678654263 0.791441740103188 0.791441740103188
Slc24a2 ENSMUSG00000037996 0.54200427865392 0.957631678136051 0.957631678136051 0.957631678136051 0.739133554902329 0.957631678136051
Slc26a7 ENSMUSG00000040569 0.898183482654752 0.898183482654752 0.834850210740357 0.898183482654752 0.702500444828441 0.898183482654752
Slc24a4 ENSMUSG00000041771 0.817684759159923 0.817684759159923 0.474003798142661 0.817684759159923 0.608807387018037 0.817684759159923
Slc9a6 ENSMUSG00000060681 0.610516407664385 0.915774611496577 0.952794664966752 0.952794664966752 0.499404338173162 0.915774611496577
Slc24a3 ENSMUSG00000063873 0.933948902380247 0.933948902380247 0.602016601246533 0.933948902380247 0.737091500661524 0.933948902380247
Slc4a5 ENSMUSG00000068323 0.602446444827455 0.854760459903678 0.813500573907216 0.854760459903678 0.854760459903678 0.854760459903678
Slc17a7 ENSMUSG00000070570 0.861799978757008 0.880432100684965 0.880432100684965 0.880432100684965 0.808683084917667 0.880432100684965
Slc8a3 ENSMUSG00000079055 0.869921934971425 0.880506081496504 0.733997140873274 0.880506081496504 0.880506081496504 0.880506081496504

Cargo trafficking to the periciliary membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bbs1 ENSMUSG00000006464 0.535252731043498 0.535252731043498 0.486936148072312 0.535252731043498 0.469722306572126 0.535252731043498
Exoc7 ENSMUSG00000020792 0.865240848199277 0.877677248195614 0.591264128545861 0.877677248195614 0.877677248195614 0.877677248195614
Ttc8 ENSMUSG00000021013 0.719390438614795 0.921389481967084 0.921389481967084 0.921389481967084 0.607740786546488 0.921389481967084
Arl6 ENSMUSG00000022722 0.566864459187481 0.949646031228839 0.949646031228839 0.949646031228839 0.883901627326227 0.949646031228839
Arl3 ENSMUSG00000025035 0.758111755078801 0.97166325309163 0.641306791483619 0.97166325309163 0.97166325309163 0.97166325309163
Bbs4 ENSMUSG00000025235 0.809736044283554 0.874560766809878 0.436365037051699 0.874560766809878 0.874560766809878 0.874560766809878
Lztfl1 ENSMUSG00000025245 0.241493453021677 0.362240179532515 0.239981407729023 0.362240179532515 0.7581550549986 0.7581550549986
Exoc4 ENSMUSG00000029763 0.535214850816684 0.535214850816684 0.26293166955306 0.535214850816684 0.474542135548828 0.535214850816684
Rho ENSMUSG00000030324 0.757266463676936 0.836801121052075 0.836801121052075 0.836801121052075 0.378777142477677 0.836801121052075
Cnga4 ENSMUSG00000030897 0.186199731629399 0.279299597444098 0.466165544799658 0.466165544799658 0.101073112177992 0.279299597444098
Bbs2 ENSMUSG00000031755 0.743202922243233 0.743202922243233 0.690115844444411 0.743202922243233 0.512070547999815 0.743202922243233
Exoc3 ENSMUSG00000034152 0.545689894474128 0.684283375866065 0.684283375866065 0.684283375866065 0.427067701967243 0.684283375866065
Bbs7 ENSMUSG00000037325 0.455256964026811 0.785352682969664 0.785352682969664 0.785352682969664 0.627220688152427 0.785352682969664
Sstr3 ENSMUSG00000044933 0.957335925596066 0.957335925596066 0.909826173730148 0.957335925596066 0.908151531264249 0.957335925596066
Mchr1 ENSMUSG00000050164 0.68177730390465 0.987302260313301 0.987302260313301 0.987302260313301 0.883030886607437 0.987302260313301
Bbs5 ENSMUSG00000063145 0.644141326225708 0.927613096268093 0.899417726942463 0.927613096268093 0.927613096268093 0.927613096268093

violet

Extracellular matrix organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Timp1 ENSMUSG00000001131 0.701579640673913 0.88027845423189 0.88027845423189 0.88027845423189 0.846026670370746 0.88027845423189
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Cma1 ENSMUSG00000022225 0.894908269528109 0.894908269528109 0.253992586635692 0.551337263590032 0.367558175726688 0.551337263590032
Lox ENSMUSG00000024529 0.322281952135258 0.846441991589067 0.733809842333528 0.846441991589067 0.846441991589067 0.846441991589067
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502
Mmp2 ENSMUSG00000031740 0.7670087003083 0.7670087003083 0.271403302864031 0.711395653370274 0.474263768913516 0.711395653370274
Tnxb ENSMUSG00000033327 0.607759682505579 0.911639523758369 0.912012612460934 0.912012612460934 0.28387041763613 0.85161125290839
Mfap4 ENSMUSG00000042436 0.962206177361031 0.962206177361031 0.231924461114414 0.34788669167162 0.218427956090299 0.34788669167162

Crosslinking of collagen fibrils

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Lox ENSMUSG00000024529 0.322281952135258 0.846441991589067 0.733809842333528 0.846441991589067 0.846441991589067 0.846441991589067
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502

Degradation of the extracellular matrix

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Timp1 ENSMUSG00000001131 0.701579640673913 0.88027845423189 0.88027845423189 0.88027845423189 0.846026670370746 0.88027845423189
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Cma1 ENSMUSG00000022225 0.894908269528109 0.894908269528109 0.253992586635692 0.551337263590032 0.367558175726688 0.551337263590032
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502
Mmp2 ENSMUSG00000031740 0.7670087003083 0.7670087003083 0.271403302864031 0.711395653370274 0.474263768913516 0.711395653370274

ECM proteoglycans

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502
Tnxb ENSMUSG00000033327 0.607759682505579 0.911639523758369 0.912012612460934 0.912012612460934 0.28387041763613 0.85161125290839

GP1b-IX-V activation signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502

Platelet Adhesion to exposed collagen

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502

Anchoring fibril formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502

Collagen degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502
Mmp2 ENSMUSG00000031740 0.7670087003083 0.7670087003083 0.271403302864031 0.711395653370274 0.474263768913516 0.711395653370274

Metabolism of Angiotensinogen to Angiotensins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cpa3 ENSMUSG00000001865 0.288489681662132 0.667999416863803 0.713849226621176 0.713849226621176 0.445332944575868 0.667999416863803
Cma1 ENSMUSG00000022225 0.894908269528109 0.894908269528109 0.253992586635692 0.551337263590032 0.367558175726688 0.551337263590032

eNOS activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cav1 ENSMUSG00000007655 0.638441455414191 0.902615021511097 0.550885396038359 0.902615021511097 0.902615021511097 0.902615021511097
Ddah1 ENSMUSG00000028194 0.797504421220371 0.981104752263413 0.840417803310516 0.981104752263413 0.981104752263413 0.981104752263413

Activation of Matrix Metalloproteinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Timp1 ENSMUSG00000001131 0.701579640673913 0.88027845423189 0.88027845423189 0.88027845423189 0.846026670370746 0.88027845423189
Cma1 ENSMUSG00000022225 0.894908269528109 0.894908269528109 0.253992586635692 0.551337263590032 0.367558175726688 0.551337263590032
Mmp2 ENSMUSG00000031740 0.7670087003083 0.7670087003083 0.271403302864031 0.711395653370274 0.474263768913516 0.711395653370274

Metabolism of nitric oxide: NOS3 activation and regulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cav1 ENSMUSG00000007655 0.638441455414191 0.902615021511097 0.550885396038359 0.902615021511097 0.902615021511097 0.902615021511097
Ddah1 ENSMUSG00000028194 0.797504421220371 0.981104752263413 0.840417803310516 0.981104752263413 0.981104752263413 0.981104752263413

Assembly of collagen fibrils and other multimeric structures

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 0.274978970934853 0.41246845640228 0.241521185543086 0.41246845640228 0.915141501680505 0.915141501680505
Lox ENSMUSG00000024529 0.322281952135258 0.846441991589067 0.733809842333528 0.846441991589067 0.846441991589067 0.846441991589067
Col1a2 ENSMUSG00000029661 0.583039156974146 0.725355248474502 0.110043237151779 0.330129711455337 0.725355248474502 0.725355248474502

Analysis performed by Ann Wells

The Carter Lab The Jackson Laboratory 2023

ann.wells@jax.org