Assessment of Genes in Pathway Analysis ANOVA Small Intestine

Introduction

This dataset contains nine tissues (heart, hippocampus, hypothalamus, kidney, liver, prefrontal cortex, skeletal muscle, small intestine, and spleen) from C57BL/6J mice that were fed 2-deoxyglucose (6g/L) through their drinking water for 96hrs or 4wks. 96hr mice were given their 2DG treatment 2 weeks after the other cohort started the 4 week treatment. The organs from the mice were harvested and processed for metabolomics and transcriptomics. The data in this document pertains to the transcriptomics data only. The counts that were used were FPKM normalized before being log transformed. It was determined that sample A113 had low RNAseq quality and through further analyses with PCA, MA plots, and clustering was an outlier and will be removed for the rest of the analyses performed. This document will the significance of the main effects and their interaction for each gene in each module.

needed.packages <- c("tidyverse", "here", "functional", "gplots", "dplyr", "GeneOverlap", "R.utils", "reshape2","magrittr","data.table", "RColorBrewer","preprocessCore", "ARTool","emmeans", "phia", "gprofiler2","rlist", "plotly","kableExtra","foreach","doParallel","doFuture","downloadthis")
for(i in 1:length(needed.packages)){library(needed.packages[i], character.only = TRUE)}

source(here("source_files","WGCNA_source.R"))

WGCNA.pathway <-readRDS(here("Data","Small Intestine","Chang_B6_96hr_4wk_gprofiler_pathway_annotation_list_small_intestine_WGCNA.RData"))

WGCNA.gene <-readRDS(here("Data","Small Intestine","Chang_B6_96hr_4wk_gprofiler_gene_annotation_list_small_intestine_WGCNA.RData"))

tdata.FPKM.sample.info <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_phenotypes.RData"))

tdata.FPKM <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_numeric.RData"))

log.tdata.FPKM <- log(tdata.FPKM + 1)
log.tdata.FPKM <- as.data.frame(log.tdata.FPKM)

log.tdata.FPKM.sample.info <- cbind(log.tdata.FPKM, tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()

log.tdata.FPKM.subset <- log.tdata.FPKM[,colMeans(log.tdata.FPKM != 0) > 0.5] 

log.tdata.FPKM.sample.info.subset <- cbind(log.tdata.FPKM.subset,tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()

log.tdata.FPKM.sample.info.subset.small.intestine <- log.tdata.FPKM.sample.info.subset %>% rownames_to_column() %>% filter(Tissue == "Small Intestine") %>% column_to_rownames()

ensembl.location <- readRDS(here("Data","Ensembl_gene_id_and_location.RData"))

Matched<-readRDS(here("Data","Small Intestine","Annotated_genes_in_small_intestine_WGCNA_Chang_B6_96hr_4wk.RData"))


module.names <- Matched$X..Module.
name <- str_split(module.names,"_")
samples <-c()
for(i in 1:length(name)){
samples[[i]] <- name[[i]][2]
}  
name2 <- stringr::str_split(samples,"\"")
mod.names <- c()
for(i in 1:length(name2)){
   mod.names[[i]] <- name2[[i]][1]
}
name2 <- unlist(mod.names)
modules <- unique(mod.names)
modules <- unlist(modules)

ANOVA

log.tdata.FPKM.sample.info.subset.small.intestine$Time <- as.factor(log.tdata.FPKM.sample.info.subset.small.intestine$Time)
log.tdata.FPKM.sample.info.subset.small.intestine$Treatment <- as.factor(log.tdata.FPKM.sample.info.subset.small.intestine$Treatment)

ANOVA.gene.pathways(WGCNA.gene, log.tdata.FPKM.sample.info.subset.small.intestine)

aliceblue

Metabolic pathways

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Ckmt1	ENSMUSG00000000308	0.711854160331342	0.711854160331342	0.29252580908486	0.711854160331342	0.711240436189781	0.711854160331342
Comt	ENSMUSG00000000326	1	1	0.21549027811633	0.64647083434899	0.640355507848752	0.960533261773128
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Cyp17a1	ENSMUSG00000003555	0.0751163767602349	0.225349130280705	0.515249728559994	0.515249728559994	0.45149265530335	0.515249728559994
Man1a	ENSMUSG00000003746	0.21549027811633	0.64647083434899	0.780851835278818	0.780851835278818	0.643359829732651	0.780851835278818
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Nmrk2	ENSMUSG00000004939	0.84934104438081	0.84934104438081	0.844957132138656	0.84934104438081	0.776581912359068	0.84934104438081
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Cs	ENSMUSG00000005683	0.454942951775341	0.682414427663011	0.17433930265919	0.523017907977569	0.711650020253571	0.711650020253571
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Shpk	ENSMUSG00000005951	0.398829756175299	0.598244634262948	0.398108175780842	0.598244634262948	0.781170242226513	0.781170242226513
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
B4galnt1	ENSMUSG00000006731	0.853372965654504	0.853694531487825	0.18064054691103	0.541921640733091	0.853694531487825	0.853694531487825
Neu1	ENSMUSG00000007038	0.926333123228344	0.926333123228344	0.575536202757516	0.863304304136274	0.514300775319626	0.863304304136274
Hmgcll1	ENSMUSG00000007908	0.397384062266614	0.7802108304765	0.643359829732651	0.7802108304765	0.7802108304765	0.7802108304765
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Pigyl	ENSMUSG00000010607	0.450444934184774	0.450444934184774	0.294820734456232	0.442231101684348	0.0953125666339397	0.285937699901819
Plcd1	ENSMUSG00000010660	0.343537039781257	0.679320738524319	0.452880492349546	0.679320738524319	0.708534948098331	0.708534948098331
Adssl1	ENSMUSG00000011148	0.255158975839805	0.382738463759707	0.781011212316137	0.781011212316137	0.0967032506702098	0.290109752010629
Aldh1a3	ENSMUSG00000015134	0.255530331334265	0.566593564630738	0.395928178642446	0.566593564630738	0.566593564630738	0.566593564630738
Sirt2	ENSMUSG00000015149	0.853480389728993	0.853480389728993	0.255901190956604	0.767703572869812	0.781170242226513	0.853480389728993
Cyp2j9	ENSMUSG00000015224	0.446194239410717	0.669291359116075	0.0964252305385472	0.289275691615642	0.851061028660105	0.851061028660105
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Chdh	ENSMUSG00000015970	0.782117202022501	0.782117202022501	0.453225835454266	0.679838753181399	0.452880492349546	0.679838753181399
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Mtmr4	ENSMUSG00000018401	0.254414773803597	0.639337105615665	0.454600801949285	0.639337105615665	0.639337105615665	0.639337105615665
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Mgat4c	ENSMUSG00000019888	0.433220407661116	0.649830611491673	0.0360718394194657	0.108215518258397	0.757479058333589	0.757479058333589
Enpp3	ENSMUSG00000019989	1	1	0.780851835278818	1	0.575824878403157	1
Hkdc1	ENSMUSG00000020080	0.576973746230334	0.711854160331342	0.711854160331342	0.711854160331342	0.255530331334266	0.711854160331342
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Ddc	ENSMUSG00000020182	0.0592616003460512	0.0888924005190768	0.00161470887631957	0.0048441266289587	0.852065168704833	0.852065168704833
Glyctk	ENSMUSG00000020258	0.926550375688041	0.926550375688041	0.120545895661628	0.223158390943484	0.148772260628989	0.223158390943484
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Adcy1	ENSMUSG00000020431	0.71082910328023	0.71082910328023	0.255530331334265	0.71082910328023	0.575536202757516	0.71082910328023
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Cmpk2	ENSMUSG00000020638	0.926658283600152	0.926658283600152	0.78180291566155	0.926658283600152	0.926550375688041	0.926658283600152
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Arg2	ENSMUSG00000021125	0.853694531487825	1	0.0733738589968007	0.220121576990402	1	1
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Fbp2	ENSMUSG00000021456	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.400265374208515	0.926550375688041
Sdha	ENSMUSG00000021577	0.711240436189782	0.711240436189782	0.511742979522636	0.711240436189782	0.454600801949285	0.711240436189782
Acot12	ENSMUSG00000021620	0.851732715229127	0.926550375688041	0.641867098978198	0.926550375688041	0.926550375688041	0.926550375688041
Ckmt2	ENSMUSG00000021622	0.381566259882379	0.710416009055326	0.710416009055326	0.710416009055326	0.625832387442502	0.710416009055326
Pde8b	ENSMUSG00000021684	0.0583853430099098	0.0875780145148646	0.0236697127745139	0.0710091383235417	0.195291845935736	0.195291845935736
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Glud1	ENSMUSG00000021794	0.148115998140415	0.222173997210623	0.044737329683373	0.134211989050119	0.638824656785692	0.638824656785692
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Dhrs4	ENSMUSG00000022210	0.636229315311352	0.636229315311352	0.0219958379984644	0.0659875139953933	0.636229315311352	0.636229315311352
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Adcy8	ENSMUSG00000022376	0.137820633917778	0.369143170438182	0.246095446958788	0.369143170438182	0.703999362653679	0.703999362653679
Gpt	ENSMUSG00000022546	0.343537039781257	0.515305559671886	0.329576740674783	0.515305559671886	0.569937449249116	0.569937449249116
Oplah	ENSMUSG00000022562	0.45596561163947	0.683948417459205	0.215127611919161	0.645382835757484	0.853694531487825	0.853694531487825
Tymp	ENSMUSG00000022615	0.178901132102685	0.269918683616058	0.179945789077372	0.269918683616058	0.642366752097095	0.642366752097095
Gbe1	ENSMUSG00000022707	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501	0.146141353215796	0.438424059647387
Cpox	ENSMUSG00000022742	0.711034989117171	0.711034989117171	0.206668954082487	0.62000686224746	0.637793186752488	0.711034989117171
B4galt4	ENSMUSG00000022793	0.853907737111068	0.853907737111068	0.295581119060361	0.443371678590541	0.204424977646738	0.443371678590541
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Rgn	ENSMUSG00000023070	0.642864324224729	0.852940894477647	0.173632433887832	0.520897301663497	0.852940894477647	0.852940894477647
Pisd	ENSMUSG00000023452	0.78180291566155	0.853372965654504	0.400265374208515	0.853372965654504	0.853372965654504	0.853372965654504
Pigx	ENSMUSG00000023791	0.5155648232968	0.7733472349452	0.926333123228344	0.926333123228344	0.299349060054895	0.7733472349452
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Cbs	ENSMUSG00000024039	0.51270683838022	0.772874592839992	1	1	0.515249728559994	0.772874592839992
Xdh	ENSMUSG00000024066	0.119631084167591	0.358893252502774	0.395196379647461	0.592794569471191	0.633039971999413	0.633039971999413
Hagh	ENSMUSG00000024158	0.5155648232968	0.5155648232968	0.0331400397096515	0.0994201191289544	0.255530331334266	0.383295497001398
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Asah2	ENSMUSG00000024887	0.711854160331342	0.711854160331342	0.578113371816017	0.711854160331342	0.514934023620344	0.711854160331342
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Aldh18a1	ENSMUSG00000025007	0.337435786255283	0.506153679382925	0.0756145297453646	0.226843589236094	0.773122046545957	0.773122046545957
Gyk	ENSMUSG00000025059	0.0741204440774082	0.11155406640886	0.144157978128026	0.144157978128026	0.0743693776059064	0.11155406640886
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Cyp2c44	ENSMUSG00000025197	0.194519294776045	0.417462449597138	0.851061028660105	0.851061028660105	0.278308299731425	0.417462449597138
Scd2	ENSMUSG00000025203	0.569937449249116	0.569937449249116	0.147458757705094	0.442376273115283	0.389247465657472	0.569937449249116
Dgka	ENSMUSG00000025357	0.0919695072173338	0.275908521652001	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Dtymk	ENSMUSG00000026281	0.782117202022501	0.853694531487825	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825
Lct	ENSMUSG00000026354	0.708745765211584	0.852832278580641	0.453570536021945	0.852832278580641	0.852832278580641	0.852832278580641
Bpnt1	ENSMUSG00000026617	0.293293089483362	0.439939634225043	1	1	0.261555237955603	0.439939634225043
Ak1	ENSMUSG00000026817	0.216214347033995	0.324321520550992	0.09586901335616	0.28760704006848	0.926333123228344	0.926333123228344
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Car13	ENSMUSG00000027555	0.853480389728993	0.853480389728993	0.399548817627028	0.853480389728993	0.853372965654504	0.853480389728993
Car2	ENSMUSG00000027562	0.514934023620345	0.706831781264721	0.706831781264721	0.706831781264721	0.444394285043028	0.706831781264721
Sis	ENSMUSG00000027790	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853694531487825	0.853694531487825
Gmps	ENSMUSG00000027823	0.447621891168214	0.67143283675232	0.772410589885492	0.772410589885492	0.146800541856249	0.440401625568746
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Ahcyl1	ENSMUSG00000027893	0.23713006400812	0.71139019202436	0.774871910813158	0.774871910813158	0.769866760519794	0.774871910813158
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Pip5k1a	ENSMUSG00000028126	0.399548817627028	0.865889271386954	0.577259514257969	0.865889271386954	1	1
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Aldob	ENSMUSG00000028307	0.775217051297351	0.849805525376199	0.849805525376199	0.849805525376199	0.570836132666921	0.849805525376199
Txndc12	ENSMUSG00000028567	0.300095920620218	0.864169452918291	0.92589277149125	0.92589277149125	0.576112968612194	0.864169452918291
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Aldh4a1	ENSMUSG00000028737	0.455625354715449	0.766645874397711	0.853049270252403	0.853049270252403	0.511097249598474	0.766645874397711
Ak2	ENSMUSG00000028792	0.0766111619812296	0.229833485943689	0.283930443883615	0.425895665825422	0.710001140920767	0.710001140920767
Inpp5b	ENSMUSG00000028894	1	1	0.772767153280156	1	0.122484825003983	0.367454475011948
Bst1	ENSMUSG00000029082	0.782117202022501	0.782117202022501	0.347639524025037	0.782117202022501	0.642366752097095	0.782117202022501
Pi4k2b	ENSMUSG00000029186	0.293293089483362	0.852940894477647	0.852940894477647	0.852940894477647	0.779888212132595	0.852940894477647
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Enoph1	ENSMUSG00000029326	0.456305241393103	0.684457862089655	0.453570536021945	0.684457862089655	1	1
Psph	ENSMUSG00000029446	0.570836132666921	0.706616781330066	0.706616781330066	0.706616781330066	0.345037391052887	0.706616781330066
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Aass	ENSMUSG00000029695	0.166489709738751	0.166489709738751	0.0287722902807987	0.0863168708423962	0.0642056836831391	0.0963085255247086
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cmas	ENSMUSG00000030282	1	1	0.712057867818062	1	0.142165951159432	0.426497853478296
Cyp2b10	ENSMUSG00000030483	0.577829325134931	0.577829325134931	0.45596561163947	0.577829325134931	0.514300775319626	0.577829325134931
Me3	ENSMUSG00000030621	0.397384062266614	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Acsm3	ENSMUSG00000030935	0.044926265292481	0.134778795877443	0.853694531487825	0.853694531487825	0.575824878403157	0.853694531487825
Acsm5	ENSMUSG00000030972	0.212942741031873	0.63882822309562	0.852723421673413	0.924930181917758	0.924930181917758	0.924930181917758
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344
Pkm	ENSMUSG00000032294	1	1	0.342026805366747	1	0.92589277149125	1
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933
Car12	ENSMUSG00000032373	0.578396848531894	0.867595272797842	0.255530331334266	0.766590994002797	0.926333123228344	0.926333123228344
Plod2	ENSMUSG00000032374	0.0106683870753909	0.0320051612261727	0.398108175780842	0.597162263671263	0.710001140920767	0.710001140920767
Alas1	ENSMUSG00000032786	0.0451153644990944	0.135346093497283	0.327972855903274	0.49195928385491	0.774871910813158	0.774871910813158
Agpat1	ENSMUSG00000034254	0.853907737111068	0.853907737111068	0.575824878403157	0.853907737111068	0.78180291566155	0.853907737111068
Dak	ENSMUSG00000034371	0.179945789077372	0.539837367232115	0.567818482366294	0.851727723549442	0.926003599371281	0.926003599371281
Inpp5j	ENSMUSG00000034570	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344	0.853372965654504	0.926333123228344
Gns	ENSMUSG00000034707	0.120850531362929	0.362551594088788	0.852832278580641	0.852832278580641	0.509144723230069	0.763717084845103
Neu3	ENSMUSG00000035239	0.295581119060361	0.443371678590541	0.245326864841171	0.443371678590541	0.852940894477647	0.852940894477647
Galm	ENSMUSG00000035473	0.706616781330066	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Xylb	ENSMUSG00000035769	0.924286968561133	0.924286968561133	0.287873078401389	0.863619235204168	0.636229315311352	0.924286968561133
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Prodh2	ENSMUSG00000036892	0.559988304776178	0.559988304776178	0.431680053324131	0.559988304776178	0.490096264582703	0.559988304776178
Gnpnat1	ENSMUSG00000037722	0.505838378028518	0.637274134311157	0.239102873501138	0.637274134311157	0.637274134311157	0.637274134311157
Gmds	ENSMUSG00000038372	0.299349060054895	0.299349060054895	0.299349060054895	0.299349060054895	0.252545530864481	0.299349060054895
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Adk	ENSMUSG00000039197	0.515564823296801	0.773347234945201	0.255530331334266	0.766590994002797	0.78180291566155	0.78180291566155
Prdm16	ENSMUSG00000039410	0.7802108304765	0.7802108304765	0.511097249598474	0.7802108304765	0.710208797518812	0.7802108304765
Dse	ENSMUSG00000039497	0.295581119060361	0.297095062262362	0.146800541856249	0.297095062262362	0.297095062262362	0.297095062262362
Lap3	ENSMUSG00000039682	0.148115998140415	0.444347994421246	0.454600801949285	0.681901202923927	0.78180291566155	0.78180291566155
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Pde9a	ENSMUSG00000041119	0.643853282854191	0.643853282854191	0.0116356061791785	0.0349068185375355	0.25141795904251	0.377126938563765
Car8	ENSMUSG00000041261	0.287873078401389	0.5155648232968	0.508488713161374	0.5155648232968	0.5155648232968	0.5155648232968
Bbox1	ENSMUSG00000041660	0.321747661812897	0.321747661812897	0.0834655302699765	0.250396590809929	0.220723922642366	0.321747661812897
Coq5	ENSMUSG00000041733	1	1	0.575536202757516	0.863304304136274	0.341647690705446	0.863304304136274
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Sephs2	ENSMUSG00000049091	0.0321889748775513	0.0482834623163269	0.0129100470219435	0.0387301410658306	0.694011247640131	0.694011247640131
Gal3st1	ENSMUSG00000049721	0.450094379653806	0.638824656785692	0.0158546704257246	0.0475640112771739	0.638824656785692	0.638824656785692
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Gnpda1	ENSMUSG00000052102	0.345410946355104	0.926550375688041	0.926550375688041	0.926550375688041	0.711650020253571	0.926550375688041
Mat2a	ENSMUSG00000053907	0.452880492349546	0.679320738524319	0.0908536824179312	0.272561047253794	0.9255572759333	0.9255572759333
Ndst1	ENSMUSG00000054008	0.450094379653806	0.675141569480709	0.851732715229127	0.851732715229127	0.144820068500793	0.43446020550238
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
B4galt6	ENSMUSG00000056124	0.578113371816017	0.867170057724026	0.0164739112492867	0.0494217337478601	0.926441990075769	0.926441990075769
Gadl1	ENSMUSG00000056880	0.650262661949838	0.650262661949838	0.650262661949838	0.650262661949838	0.280002632651122	0.650262661949838
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Idi1	ENSMUSG00000058258	0.0575107614292585	0.172532284287776	0.9255572759333	0.9255572759333	0.570836132666921	0.856254199000382
Gda	ENSMUSG00000058624	0.576973746230334	0.865460619345501	0.575824878403157	0.865460619345501	0.926333123228344	0.926333123228344
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931
Mppe1	ENSMUSG00000062526	0.044926265292481	0.0673893979387216	0.00247508107184991	0.00742524321554973	0.109793509122179	0.109793509122179
Eno1	ENSMUSG00000063524	0.853372965654504	0.853372965654504	0.0969812105731562	0.145471815859734	0.0566379395854604	0.145471815859734
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833
Aox3	ENSMUSG00000064294	0.575536202757516	1	1	1	0.778911768167544	1
mt-Nd6	ENSMUSG00000064368	0.216214347033995	0.5155648232968	0.5155648232968	0.5155648232968	0.511097249598474	0.5155648232968
Dhrs3	ENSMUSG00000066026	0.0766111619812296	0.114916742971844	0.000819575681707138	0.00245872704512142	0.7802108304765	0.7802108304765
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Impad1	ENSMUSG00000066324	0.17610058307789	0.264150874616835	0.138156294413154	0.264150874616835	0.635703516568382	0.635703516568382
Vkorc1l1	ENSMUSG00000066735	0.641867098978197	0.641867098978197	0.573791743469336	0.641867098978197	0.640861491578951	0.641867098978197
Pnp2	ENSMUSG00000068417	0.0964252305385471	0.289275691615641	0.398108175780842	0.597162263671263	0.926550375688041	0.926550375688041
Mgam	ENSMUSG00000068587	0.255530331334266	0.348008842235184	0.120850531362929	0.348008842235184	0.348008842235184	0.348008842235184
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Selenbp1	ENSMUSG00000068874	0.926333123228344	0.926333123228344	0.346899083932133	0.926333123228344	0.711240436189781	0.926333123228344
Rdh16	ENSMUSG00000069456	0.455625354715449	0.514300775319626	0.514300775319626	0.514300775319626	0.300095920620218	0.514300775319626
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724
Gsta1	ENSMUSG00000074183	0.0231500557096833	0.06945016712905	0.642366752097095	0.642366752097095	0.345410946355104	0.518116419532656
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Amd1	ENSMUSG00000075232	0.781170242226513	0.781170242226513	0.451840588205062	0.781170242226513	0.711854160331342	0.781170242226513
Neu2	ENSMUSG00000079434	0.392243127063687	0.588364690595531	0.190629863394776	0.571889590184328	0.92356607045265	0.92356607045265
Gm11128	ENSMUSG00000079495	0.577829325134931	0.71082910328023	0.71082910328023	0.71082910328023	0.578113371816017	0.71082910328023
Galnt2	ENSMUSG00000089704	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155	0.710416009055326	0.78180291566155
Rdh1	ENSMUSG00000089789	0.926496242814507	0.926496242814507	0.514617706526787	0.926496242814507	0.853694531487825	0.926496242814507
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Galnt4	ENSMUSG00000090035	0.853694531487825	0.926496242814507	0.853694531487825	0.926496242814507	0.926496242814507	0.926496242814507
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Steroid biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Soat2	ENSMUSG00000023045	0.216214347033995	0.648643041101984	1	1	0.710208797518812	1
Lipa	ENSMUSG00000024781	0.633039971999413	0.923443907074248	0.162867964743396	0.488603894230187	0.923443907074248	0.923443907074248
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344

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Glycerophospholipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Pla1a	ENSMUSG00000002847	0.119631084167591	0.323235417174495	0.21549027811633	0.323235417174495	0.578113371816017	0.578113371816017
Lpcat3	ENSMUSG00000004270	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739	0.853801250889739	0.853801250889739
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Pisd	ENSMUSG00000023452	0.78180291566155	0.853372965654504	0.400265374208515	0.853372965654504	0.853372965654504	0.853372965654504
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Dgka	ENSMUSG00000025357	0.0919695072173338	0.275908521652001	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Lpgat1	ENSMUSG00000026623	1	1	0.926003599371282	1	0.57113445032749	1
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Agpat1	ENSMUSG00000034254	0.853907737111068	0.853907737111068	0.575824878403157	0.853907737111068	0.78180291566155	0.853907737111068
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724

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Peroxisome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pex19	ENSMUSG00000003464	0.148115998140415	0.222173997210623	0.0958690133561599	0.222173997210623	0.513665062682276	0.513665062682276
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Hmgcll1	ENSMUSG00000007908	0.397384062266614	0.7802108304765	0.643359829732651	0.7802108304765	0.7802108304765	0.7802108304765
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Dhrs4	ENSMUSG00000022210	0.636229315311352	0.636229315311352	0.0219958379984644	0.0659875139953933	0.636229315311352	0.636229315311352
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Xdh	ENSMUSG00000024066	0.119631084167591	0.358893252502774	0.395196379647461	0.592794569471191	0.633039971999413	0.633039971999413
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Abcd3	ENSMUSG00000028127	0.853907737111068	0.853907737111068	0.177153312234059	0.531459936702178	0.853907737111068	0.853907737111068
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092

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Sulfur metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Bpnt1	ENSMUSG00000026617	0.293293089483362	0.439939634225043	1	1	0.261555237955603	0.439939634225043
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833
Impad1	ENSMUSG00000066324	0.17610058307789	0.264150874616835	0.138156294413154	0.264150874616835	0.635703516568382	0.635703516568382
Selenbp1	ENSMUSG00000068874	0.926333123228344	0.926333123228344	0.346899083932133	0.926333123228344	0.711240436189781	0.926333123228344

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Bile secretion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc5a1	ENSMUSG00000011034	0.853049270252403	0.853372965654504	0.710416009055326	0.853372965654504	0.853372965654504	0.853372965654504
Adcy1	ENSMUSG00000020431	0.71082910328023	0.71082910328023	0.255530331334265	0.71082910328023	0.575536202757516	0.71082910328023
Adcy8	ENSMUSG00000022376	0.137820633917778	0.369143170438182	0.246095446958788	0.369143170438182	0.703999362653679	0.703999362653679
Abcg8	ENSMUSG00000024254	0.297848640636702	0.710001140920767	0.710001140920767	0.710001140920767	0.640355507848752	0.710001140920767
Abcc2	ENSMUSG00000025194	0.45596561163947	0.683948417459205	0.348008842235184	0.683948417459205	0.781170242226513	0.781170242226513
Car2	ENSMUSG00000027562	0.514934023620345	0.706831781264721	0.706831781264721	0.706831781264721	0.444394285043028	0.706831781264721
Nceh1	ENSMUSG00000027698	0.148772260628989	0.148772260628989	0.00253244992826164	0.00759734978478493	0.0488765001588118	0.0733147502382177
Abcg2	ENSMUSG00000029802	0.577829325134931	0.78148726569172	0.141500034183268	0.424500102549803	0.78148726569172	0.78148726569172
Aqp9	ENSMUSG00000032204	0.11810342389482	0.177155135842229	0.92589277149125	0.92589277149125	0.00649065913668484	0.0194719774100545
Atp1a1	ENSMUSG00000033161	0.148772260628989	0.223158390943483	0.141500034183268	0.223158390943483	0.925669613555092	0.925669613555092
Slc51a	ENSMUSG00000035699	0.704220158648919	0.704220158648919	0.286303237509397	0.704220158648919	0.563485358844814	0.704220158648919
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Slc9a3	ENSMUSG00000036123	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504
Nr0b2	ENSMUSG00000037583	0.777755996383525	0.851061028660105	0.851061028660105	0.851061028660105	0.144489143676808	0.433467431030423
Abcg5	ENSMUSG00000040505	0.643359829732651	0.78180291566155	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155
Abcb1a	ENSMUSG00000040584	0.11993617140438	0.179904257106569	0.024062085667391	0.0721862570021729	0.216214347033995	0.216214347033995
Cftr	ENSMUSG00000041301	0.0969812105731562	0.290943631719469	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Slc4a5	ENSMUSG00000068323	0.690028363829288	0.690028363829288	0.379206615039809	0.568809922559714	0.224181550151583	0.568809922559714
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Fat digestion and absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Npc1l1	ENSMUSG00000020447	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Abcg8	ENSMUSG00000024254	0.297848640636702	0.710001140920767	0.710001140920767	0.710001140920767	0.640355507848752	0.710001140920767
Mttp	ENSMUSG00000028158	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.7802108304765	0.781170242226513
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092
Agpat1	ENSMUSG00000034254	0.853907737111068	0.853907737111068	0.575824878403157	0.853907737111068	0.78180291566155	0.853907737111068
Abcg5	ENSMUSG00000040505	0.643359829732651	0.78180291566155	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155
Mogat2	ENSMUSG00000052396	0.118714930081337	0.35614479024401	0.300095920620218	0.450143880930327	0.578113371816017	0.578113371816017
Fabp1	ENSMUSG00000054422	0.779888212132595	0.779888212132595	0.120850531362929	0.362551594088788	0.392985378348026	0.589478067522039
Slc27a4	ENSMUSG00000059316	0.255901190956604	0.383851786434906	0.243396309647537	0.383851786434906	0.511097249598474	0.511097249598474

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Sphingolipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Neu1	ENSMUSG00000007038	0.926333123228344	0.926333123228344	0.575536202757516	0.863304304136274	0.514300775319626	0.863304304136274
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Arsa	ENSMUSG00000022620	0.347639524025037	0.454258017332816	0.177153312234059	0.454258017332816	0.454258017332816	0.454258017332816
Asah2	ENSMUSG00000024887	0.711854160331342	0.711854160331342	0.578113371816017	0.711854160331342	0.514934023620344	0.711854160331342
Neu3	ENSMUSG00000035239	0.295581119060361	0.443371678590541	0.245326864841171	0.443371678590541	0.852940894477647	0.852940894477647
Gal3st1	ENSMUSG00000049721	0.450094379653806	0.638824656785692	0.0158546704257246	0.0475640112771739	0.638824656785692	0.638824656785692
B4galt6	ENSMUSG00000056124	0.578113371816017	0.867170057724026	0.0164739112492867	0.0494217337478601	0.926441990075769	0.926441990075769
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931
Neu2	ENSMUSG00000079434	0.392243127063687	0.588364690595531	0.190629863394776	0.571889590184328	0.92356607045265	0.92356607045265

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Carbon metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Cs	ENSMUSG00000005683	0.454942951775341	0.682414427663011	0.17433930265919	0.523017907977569	0.711650020253571	0.711650020253571
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Hkdc1	ENSMUSG00000020080	0.576973746230334	0.711854160331342	0.711854160331342	0.711854160331342	0.255530331334266	0.711854160331342
Glyctk	ENSMUSG00000020258	0.926550375688041	0.926550375688041	0.120545895661628	0.223158390943484	0.148772260628989	0.223158390943484
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Fbp2	ENSMUSG00000021456	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.400265374208515	0.926550375688041
Sdha	ENSMUSG00000021577	0.711240436189782	0.711240436189782	0.511742979522636	0.711240436189782	0.454600801949285	0.711240436189782
Glud1	ENSMUSG00000021794	0.148115998140415	0.222173997210623	0.044737329683373	0.134211989050119	0.638824656785692	0.638824656785692
Gpt	ENSMUSG00000022546	0.343537039781257	0.515305559671886	0.329576740674783	0.515305559671886	0.569937449249116	0.569937449249116
Rgn	ENSMUSG00000023070	0.642864324224729	0.852940894477647	0.173632433887832	0.520897301663497	0.852940894477647	0.852940894477647
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636
Aldob	ENSMUSG00000028307	0.775217051297351	0.849805525376199	0.849805525376199	0.849805525376199	0.570836132666921	0.849805525376199
Psph	ENSMUSG00000029446	0.570836132666921	0.706616781330066	0.706616781330066	0.706616781330066	0.345037391052887	0.706616781330066
Me3	ENSMUSG00000030621	0.397384062266614	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Pkm	ENSMUSG00000032294	1	1	0.342026805366747	1	0.92589277149125	1
Dak	ENSMUSG00000034371	0.179945789077372	0.539837367232115	0.567818482366294	0.851727723549442	0.926003599371281	0.926003599371281
Eno1	ENSMUSG00000063524	0.853372965654504	0.853372965654504	0.0969812105731562	0.145471815859734	0.0566379395854604	0.145471815859734

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Retinol metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Aldh1a3	ENSMUSG00000015134	0.255530331334265	0.566593564630738	0.395928178642446	0.566593564630738	0.566593564630738	0.566593564630738
Dhrs4	ENSMUSG00000022210	0.636229315311352	0.636229315311352	0.0219958379984644	0.0659875139953933	0.636229315311352	0.636229315311352
Cyp2c44	ENSMUSG00000025197	0.194519294776045	0.417462449597138	0.851061028660105	0.851061028660105	0.278308299731425	0.417462449597138
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2b10	ENSMUSG00000030483	0.577829325134931	0.577829325134931	0.45596561163947	0.577829325134931	0.514300775319626	0.577829325134931
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Retsat	ENSMUSG00000056666	0.37881079458931	0.568216191883965	0.110273508507811	0.330820525523432	0.6978446011211	0.6978446011211
Aox3	ENSMUSG00000064294	0.575536202757516	1	1	1	0.778911768167544	1
Dhrs3	ENSMUSG00000066026	0.0766111619812296	0.114916742971844	0.000819575681707138	0.00245872704512142	0.7802108304765	0.7802108304765
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Rdh16	ENSMUSG00000069456	0.455625354715449	0.514300775319626	0.514300775319626	0.514300775319626	0.300095920620218	0.514300775319626
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Rdh1	ENSMUSG00000089789	0.926496242814507	0.926496242814507	0.514617706526787	0.926496242814507	0.853694531487825	0.926496242814507
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Pyruvate metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Acot12	ENSMUSG00000021620	0.851732715229127	0.926550375688041	0.641867098978198	0.926550375688041	0.926550375688041	0.926550375688041
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Hagh	ENSMUSG00000024158	0.5155648232968	0.5155648232968	0.0331400397096515	0.0994201191289544	0.255530331334266	0.383295497001398
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Me3	ENSMUSG00000030621	0.397384062266614	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Pkm	ENSMUSG00000032294	1	1	0.342026805366747	1	0.92589277149125	1
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1

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Chemical carcinogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Cyp2c44	ENSMUSG00000025197	0.194519294776045	0.417462449597138	0.851061028660105	0.851061028660105	0.278308299731425	0.417462449597138
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2b10	ENSMUSG00000030483	0.577829325134931	0.577829325134931	0.45596561163947	0.577829325134931	0.514300775319626	0.577829325134931
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Gsta1	ENSMUSG00000074183	0.0231500557096833	0.06945016712905	0.642366752097095	0.642366752097095	0.345410946355104	0.518116419532656
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Drug metabolism - cytochrome P450

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Fmo5	ENSMUSG00000028088	0.924286968561133	0.924286968561133	0.0497293992720784	0.149188197816235	0.450794830295118	0.676192245442677
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Aox3	ENSMUSG00000064294	0.575536202757516	1	1	1	0.778911768167544	1
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Gsta1	ENSMUSG00000074183	0.0231500557096833	0.06945016712905	0.642366752097095	0.642366752097095	0.345410946355104	0.518116419532656
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Cholesterol metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Vdac2	ENSMUSG00000021771	0.255901190956604	0.767703572869812	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Soat2	ENSMUSG00000023045	0.216214347033995	0.648643041101984	1	1	0.710208797518812	1
Abcg8	ENSMUSG00000024254	0.297848640636702	0.710001140920767	0.710001140920767	0.710001140920767	0.640355507848752	0.710001140920767
Lipa	ENSMUSG00000024781	0.633039971999413	0.923443907074248	0.162867964743396	0.488603894230187	0.923443907074248	0.923443907074248
Nceh1	ENSMUSG00000027698	0.148772260628989	0.148772260628989	0.00253244992826164	0.00759734978478493	0.0488765001588118	0.0733147502382177
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092
Apoc3	ENSMUSG00000032081	0.216214347033995	0.324321520550992	0.0756145297453648	0.226843589236094	0.78180291566155	0.78180291566155
Abcg5	ENSMUSG00000040505	0.643359829732651	0.78180291566155	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155
Pcsk9	ENSMUSG00000044254	0.926003599371281	0.926333123228344	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344

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PPAR signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Fabp6	ENSMUSG00000020405	0.757910339741814	0.919766116387509	0.346871613920738	0.919766116387509	0.919766116387509	0.919766116387509
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Gyk	ENSMUSG00000025059	0.0741204440774082	0.11155406640886	0.144157978128026	0.144157978128026	0.0743693776059064	0.11155406640886
Scd2	ENSMUSG00000025203	0.569937449249116	0.569937449249116	0.147458757705094	0.442376273115283	0.389247465657472	0.569937449249116
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Fabp3	ENSMUSG00000028773	0.162867964743396	0.244301947115094	0.0969812105731562	0.244301947115094	0.63250023504486	0.63250023504486
Me3	ENSMUSG00000030621	0.397384062266614	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Apoa5	ENSMUSG00000032079	0.708323672944427	0.708323672944427	0.0168921052924601	0.0506763158773803	0.513026869856283	0.708323672944427
Apoc3	ENSMUSG00000032081	0.216214347033995	0.324321520550992	0.0756145297453648	0.226843589236094	0.78180291566155	0.78180291566155
Fabp1	ENSMUSG00000054422	0.779888212132595	0.779888212132595	0.120850531362929	0.362551594088788	0.392985378348026	0.589478067522039
Slc27a4	ENSMUSG00000059316	0.255901190956604	0.383851786434906	0.243396309647537	0.383851786434906	0.511097249598474	0.511097249598474
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Glycerolipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Glyctk	ENSMUSG00000020258	0.926550375688041	0.926550375688041	0.120545895661628	0.223158390943484	0.148772260628989	0.223158390943484
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Gyk	ENSMUSG00000025059	0.0741204440774082	0.11155406640886	0.144157978128026	0.144157978128026	0.0743693776059064	0.11155406640886
Dgka	ENSMUSG00000025357	0.0919695072173338	0.275908521652001	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Agpat1	ENSMUSG00000034254	0.853907737111068	0.853907737111068	0.575824878403157	0.853907737111068	0.78180291566155	0.853907737111068
Dak	ENSMUSG00000034371	0.179945789077372	0.539837367232115	0.567818482366294	0.851727723549442	0.926003599371281	0.926003599371281
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Mogat2	ENSMUSG00000052396	0.118714930081337	0.35614479024401	0.300095920620218	0.450143880930327	0.578113371816017	0.578113371816017

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ABC transporters

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Abcg8	ENSMUSG00000024254	0.297848640636702	0.710001140920767	0.710001140920767	0.710001140920767	0.640355507848752	0.710001140920767
Abcc2	ENSMUSG00000025194	0.45596561163947	0.683948417459205	0.348008842235184	0.683948417459205	0.781170242226513	0.781170242226513
Abcd3	ENSMUSG00000028127	0.853907737111068	0.853907737111068	0.177153312234059	0.531459936702178	0.853907737111068	0.853907737111068
Abcb9	ENSMUSG00000029408	0.266267359102332	0.399401038653498	7.32463150534408e-05	0.000219738945160323	1	1
Abcg2	ENSMUSG00000029802	0.577829325134931	0.78148726569172	0.141500034183268	0.424500102549803	0.78148726569172	0.78148726569172
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Abca17	ENSMUSG00000035435	0.627814466256298	0.627814466256298	0.44090587739783	0.627814466256298	0.315859908885325	0.627814466256298
Abcg5	ENSMUSG00000040505	0.643359829732651	0.78180291566155	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155
Abcb1a	ENSMUSG00000040584	0.11993617140438	0.179904257106569	0.024062085667391	0.0721862570021729	0.216214347033995	0.216214347033995
Cftr	ENSMUSG00000041301	0.0969812105731562	0.290943631719469	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095

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Fatty acid degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1

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Arginine and proline metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ckmt1	ENSMUSG00000000308	0.711854160331342	0.711854160331342	0.29252580908486	0.711854160331342	0.711240436189781	0.711854160331342
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Arg2	ENSMUSG00000021125	0.853694531487825	1	0.0733738589968007	0.220121576990402	1	1
Ckmt2	ENSMUSG00000021622	0.381566259882379	0.710416009055326	0.710416009055326	0.710416009055326	0.625832387442502	0.710416009055326
Aldh18a1	ENSMUSG00000025007	0.337435786255283	0.506153679382925	0.0756145297453646	0.226843589236094	0.773122046545957	0.773122046545957
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Aldh4a1	ENSMUSG00000028737	0.455625354715449	0.766645874397711	0.853049270252403	0.853049270252403	0.511097249598474	0.766645874397711
Prodh2	ENSMUSG00000036892	0.559988304776178	0.559988304776178	0.431680053324131	0.559988304776178	0.490096264582703	0.559988304776178
Lap3	ENSMUSG00000039682	0.148115998140415	0.444347994421246	0.454600801949285	0.681901202923927	0.78180291566155	0.78180291566155
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Amd1	ENSMUSG00000075232	0.781170242226513	0.781170242226513	0.451840588205062	0.781170242226513	0.711854160331342	0.781170242226513

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Glycine, serine and threonine metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Chdh	ENSMUSG00000015970	0.782117202022501	0.782117202022501	0.453225835454266	0.679838753181399	0.452880492349546	0.679838753181399
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Glyctk	ENSMUSG00000020258	0.926550375688041	0.926550375688041	0.120545895661628	0.223158390943484	0.148772260628989	0.223158390943484
Cbs	ENSMUSG00000024039	0.51270683838022	0.772874592839992	1	1	0.515249728559994	0.772874592839992
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Psph	ENSMUSG00000029446	0.570836132666921	0.706616781330066	0.706616781330066	0.706616781330066	0.345037391052887	0.706616781330066
Alas1	ENSMUSG00000032786	0.0451153644990944	0.135346093497283	0.327972855903274	0.49195928385491	0.774871910813158	0.774871910813158
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781

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Citrate cycle (TCA cycle)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Cs	ENSMUSG00000005683	0.454942951775341	0.682414427663011	0.17433930265919	0.523017907977569	0.711650020253571	0.711650020253571
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Sdha	ENSMUSG00000021577	0.711240436189782	0.711240436189782	0.511742979522636	0.711240436189782	0.454600801949285	0.711240436189782
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345

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Metabolism of xenobiotics by cytochrome P450

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Gsta1	ENSMUSG00000074183	0.0231500557096833	0.06945016712905	0.642366752097095	0.642366752097095	0.345410946355104	0.518116419532656
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Glycolysis / Gluconeogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Hkdc1	ENSMUSG00000020080	0.576973746230334	0.711854160331342	0.711854160331342	0.711854160331342	0.255530331334266	0.711854160331342
Fbp2	ENSMUSG00000021456	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.400265374208515	0.926550375688041
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Aldob	ENSMUSG00000028307	0.775217051297351	0.849805525376199	0.849805525376199	0.849805525376199	0.570836132666921	0.849805525376199
Pkm	ENSMUSG00000032294	1	1	0.342026805366747	1	0.92589277149125	1
Galm	ENSMUSG00000035473	0.706616781330066	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Eno1	ENSMUSG00000063524	0.853372965654504	0.853372965654504	0.0969812105731562	0.145471815859734	0.0566379395854604	0.145471815859734
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1

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Butanoate metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hmgcll1	ENSMUSG00000007908	0.397384062266614	0.7802108304765	0.643359829732651	0.7802108304765	0.7802108304765	0.7802108304765
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Acsm3	ENSMUSG00000030935	0.044926265292481	0.134778795877443	0.853694531487825	0.853694531487825	0.575824878403157	0.853694531487825
Acsm5	ENSMUSG00000030972	0.212942741031873	0.63882822309562	0.852723421673413	0.924930181917758	0.924930181917758	0.924930181917758
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Proximal tubule bicarbonate reclamation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Glud1	ENSMUSG00000021794	0.148115998140415	0.222173997210623	0.044737329683373	0.134211989050119	0.638824656785692	0.638824656785692
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Car2	ENSMUSG00000027562	0.514934023620345	0.706831781264721	0.706831781264721	0.706831781264721	0.444394285043028	0.706831781264721
Atp1a1	ENSMUSG00000033161	0.148772260628989	0.223158390943483	0.141500034183268	0.223158390943483	0.925669613555092	0.925669613555092
Slc9a3	ENSMUSG00000036123	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504

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Drug metabolism - other enzymes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Tymp	ENSMUSG00000022615	0.178901132102685	0.269918683616058	0.179945789077372	0.269918683616058	0.642366752097095	0.642366752097095
Xdh	ENSMUSG00000024066	0.119631084167591	0.358893252502774	0.395196379647461	0.592794569471191	0.633039971999413	0.633039971999413
Gmps	ENSMUSG00000027823	0.447621891168214	0.67143283675232	0.772410589885492	0.772410589885492	0.146800541856249	0.440401625568746
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Ces2g	ENSMUSG00000031877	0.839040706534227	0.839040706534227	0.276193075425283	0.414289613137925	0.245546217349378	0.414289613137925
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Ces1e	ENSMUSG00000061959	0.0958690133561599	0.28760704006848	0.924639851733043	0.924639851733043	0.573498913947369	0.860248370921054
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Gsta1	ENSMUSG00000074183	0.0231500557096833	0.06945016712905	0.642366752097095	0.642366752097095	0.345410946355104	0.518116419532656
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Terpenoid backbone biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Idi1	ENSMUSG00000058258	0.0575107614292585	0.172532284287776	0.9255572759333	0.9255572759333	0.570836132666921	0.856254199000382
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Glyoxylate and dicarboxylate metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cs	ENSMUSG00000005683	0.454942951775341	0.682414427663011	0.17433930265919	0.523017907977569	0.711650020253571	0.711650020253571
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Glyctk	ENSMUSG00000020258	0.926550375688041	0.926550375688041	0.120545895661628	0.223158390943484	0.148772260628989	0.223158390943484
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636

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Metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Ckmt1	ENSMUSG00000000308	0.711854160331342	0.711854160331342	0.29252580908486	0.711854160331342	0.711240436189781	0.711854160331342
Comt	ENSMUSG00000000326	1	1	0.21549027811633	0.64647083434899	0.640355507848752	0.960533261773128
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Taco1	ENSMUSG00000001983	0.294820734456233	0.593892267963669	0.926658283600152	0.926658283600152	0.395928178642446	0.593892267963669
Pla1a	ENSMUSG00000002847	0.119631084167591	0.323235417174495	0.21549027811633	0.323235417174495	0.578113371816017	0.578113371816017
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Cyp17a1	ENSMUSG00000003555	0.0751163767602349	0.225349130280705	0.515249728559994	0.515249728559994	0.45149265530335	0.515249728559994
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Lpcat3	ENSMUSG00000004270	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739	0.853801250889739	0.853801250889739
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Nmrk2	ENSMUSG00000004939	0.84934104438081	0.84934104438081	0.844957132138656	0.84934104438081	0.776581912359068	0.84934104438081
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Cs	ENSMUSG00000005683	0.454942951775341	0.682414427663011	0.17433930265919	0.523017907977569	0.711650020253571	0.711650020253571
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Shpk	ENSMUSG00000005951	0.398829756175299	0.598244634262948	0.398108175780842	0.598244634262948	0.781170242226513	0.781170242226513
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
B4galnt1	ENSMUSG00000006731	0.853372965654504	0.853694531487825	0.18064054691103	0.541921640733091	0.853694531487825	0.853694531487825
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Neu1	ENSMUSG00000007038	0.926333123228344	0.926333123228344	0.575536202757516	0.863304304136274	0.514300775319626	0.863304304136274
Dio2	ENSMUSG00000007682	0.292909738490495	0.439364607735743	0.0546809717320726	0.164042915196218	0.511420431658568	0.511420431658568
Hmgcll1	ENSMUSG00000007908	0.397384062266614	0.7802108304765	0.643359829732651	0.7802108304765	0.7802108304765	0.7802108304765
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Cacna2d2	ENSMUSG00000010066	0.213307944885796	0.639923834657388	0.455625354715449	0.683438032073173	0.852940894477647	0.852940894477647
Slc3a2	ENSMUSG00000010095	0.148115998140416	0.375428758901986	0.250285839267991	0.375428758901986	0.778911768167544	0.778911768167544
Plcd1	ENSMUSG00000010660	0.343537039781257	0.679320738524319	0.452880492349546	0.679320738524319	0.708534948098331	0.708534948098331
Adssl1	ENSMUSG00000011148	0.255158975839805	0.382738463759707	0.781011212316137	0.781011212316137	0.0967032506702098	0.290109752010629
Tnfaip8l2	ENSMUSG00000013707	0.122484825003983	0.367454475011948	0.850151080737202	0.850151080737202	0.62976545519988	0.850151080737202
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Chdh	ENSMUSG00000015970	0.782117202022501	0.782117202022501	0.453225835454266	0.679838753181399	0.452880492349546	0.679838753181399
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Cyb5r3	ENSMUSG00000018042	0.255901190956604	0.383851786434905	0.170434860179341	0.383851786434905	0.92589277149125	0.92589277149125
Mtmr4	ENSMUSG00000018401	0.254414773803597	0.639337105615665	0.454600801949285	0.639337105615665	0.639337105615665	0.639337105615665
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Mdh2	ENSMUSG00000019179	0.347639524025037	0.347639524025037	0.0733738589968007	0.220121576990402	0.344663224299303	0.347639524025037
Dpep1	ENSMUSG00000019278	0.211110344399808	0.633331033199424	0.567513221841557	0.851269832762335	1	1
Slc6a8	ENSMUSG00000019558	0.21549027811633	0.64647083434899	0.926658283600152	0.926658283600152	0.577829325134931	0.866743987702397
Pdk4	ENSMUSG00000019577	0.035887934910603	0.0538319023659045	0.0038031455224948	0.0114094365674844	0.635703516568383	0.635703516568383
Nudt4	ENSMUSG00000020029	0.926550375688041	0.926550375688041	0.853907737111068	0.926550375688041	0.17924968721805	0.537749061654149
Slc5a8	ENSMUSG00000020062	0.762507504068942	0.762507504068942	0.00700808200338927	0.0210242460101678	0.246861959455465	0.370292939183197
Ppa1	ENSMUSG00000020089	0.640861491578951	0.778911768167544	0.698079433225416	0.778911768167544	0.778911768167544	0.778911768167544
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Ddc	ENSMUSG00000020182	0.0592616003460512	0.0888924005190768	0.00161470887631957	0.0048441266289587	0.852065168704833	0.852065168704833
Mdh1	ENSMUSG00000020321	0.853801250889739	0.853801250889739	0.576973746230334	0.853801250889739	0.643359829732651	0.853801250889739
Fabp6	ENSMUSG00000020405	0.757910339741814	0.919766116387509	0.346871613920738	0.919766116387509	0.919766116387509	0.919766116387509
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Arsg	ENSMUSG00000020604	0.922445041430936	0.922445041430936	0.0718551089340876	0.215565326802263	0.467009962776288	0.700514944164432
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Slc46a1	ENSMUSG00000020829	0.283134662157423	0.424701993236134	0.0520308460244811	0.156092538073443	0.553410011703054	0.553410011703054
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Arg2	ENSMUSG00000021125	0.853694531487825	1	0.0733738589968007	0.220121576990402	1	1
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Fbp2	ENSMUSG00000021456	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.400265374208515	0.926550375688041
Sdha	ENSMUSG00000021577	0.711240436189782	0.711240436189782	0.511742979522636	0.711240436189782	0.454600801949285	0.711240436189782
Acot12	ENSMUSG00000021620	0.851732715229127	0.926550375688041	0.641867098978198	0.926550375688041	0.926550375688041	0.926550375688041
Ckmt2	ENSMUSG00000021622	0.381566259882379	0.710416009055326	0.710416009055326	0.710416009055326	0.625832387442502	0.710416009055326
Psmd6	ENSMUSG00000021737	0.78180291566155	0.92622377157404	0.779238691542963	0.92622377157404	0.92622377157404	0.92622377157404
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Samd8	ENSMUSG00000021770	0.290984282074805	0.5155648232968	0.5155648232968	0.5155648232968	0.450794830295118	0.5155648232968
Glud1	ENSMUSG00000021794	0.148115998140415	0.222173997210623	0.044737329683373	0.134211989050119	0.638824656785692	0.638824656785692
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Gpt	ENSMUSG00000022546	0.343537039781257	0.515305559671886	0.329576740674783	0.515305559671886	0.569937449249116	0.569937449249116
Oplah	ENSMUSG00000022562	0.45596561163947	0.683948417459205	0.215127611919161	0.645382835757484	0.853694531487825	0.853694531487825
Tymp	ENSMUSG00000022615	0.178901132102685	0.269918683616058	0.179945789077372	0.269918683616058	0.642366752097095	0.642366752097095
Arsa	ENSMUSG00000022620	0.347639524025037	0.454258017332816	0.177153312234059	0.454258017332816	0.454258017332816	0.454258017332816
Gbe1	ENSMUSG00000022707	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501	0.146141353215796	0.438424059647387
Cpox	ENSMUSG00000022742	0.711034989117171	0.711034989117171	0.206668954082487	0.62000686224746	0.637793186752488	0.711034989117171
B4galt4	ENSMUSG00000022793	0.853907737111068	0.853907737111068	0.295581119060361	0.443371678590541	0.204424977646738	0.443371678590541
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cbs	ENSMUSG00000024039	0.51270683838022	0.772874592839992	1	1	0.515249728559994	0.772874592839992
Xdh	ENSMUSG00000024066	0.119631084167591	0.358893252502774	0.395196379647461	0.592794569471191	0.633039971999413	0.633039971999413
Nudt3	ENSMUSG00000024213	0.514934023620345	0.514934023620345	0.511742979522636	0.514934023620345	0.346899083932132	0.514934023620345
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Slc23a1	ENSMUSG00000024354	0.700627001620904	0.925331064166297	0.344663224299303	0.925331064166297	0.925331064166297	0.925331064166297
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Gna14	ENSMUSG00000024697	0.853587578053106	0.926278508226733	0.0417377002086289	0.125213100625887	0.926278508226733	0.926278508226733
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Acy3	ENSMUSG00000024866	0.853372965654504	0.853372965654504	0.118409250205154	0.355227750615461	0.78180291566155	0.853372965654504
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Asah2	ENSMUSG00000024887	0.711854160331342	0.711854160331342	0.578113371816017	0.711854160331342	0.514934023620344	0.711854160331342
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Aldh18a1	ENSMUSG00000025007	0.337435786255283	0.506153679382925	0.0756145297453646	0.226843589236094	0.773122046545957	0.773122046545957
Gyk	ENSMUSG00000025059	0.0741204440774082	0.11155406640886	0.144157978128026	0.144157978128026	0.0743693776059064	0.11155406640886
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Abcc2	ENSMUSG00000025194	0.45596561163947	0.683948417459205	0.348008842235184	0.683948417459205	0.781170242226513	0.781170242226513
Scd2	ENSMUSG00000025203	0.569937449249116	0.569937449249116	0.147458757705094	0.442376273115283	0.389247465657472	0.569937449249116
Acot9	ENSMUSG00000025287	0.343537039781257	0.590587491403246	0.393724994268831	0.590587491403246	0.779888212132595	0.779888212132595
Pfkfb4	ENSMUSG00000025648	0.253294730253594	0.519791938509652	0.638310022345193	0.638310022345193	0.346527959006435	0.519791938509652
Dtymk	ENSMUSG00000026281	0.782117202022501	0.853694531487825	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825
Bpnt1	ENSMUSG00000026617	0.293293089483362	0.439939634225043	1	1	0.261555237955603	0.439939634225043
Lpgat1	ENSMUSG00000026623	1	1	0.926003599371282	1	0.57113445032749	1
Acbd7	ENSMUSG00000026644	0.231130630776632	0.231130630776632	0.231130630776632	0.231130630776632	0.0680278868695481	0.204083660608644
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Ak1	ENSMUSG00000026817	0.216214347033995	0.324321520550992	0.09586901335616	0.28760704006848	0.926333123228344	0.926333123228344
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Fam73b	ENSMUSG00000026858	0.575824878403157	0.575824878403157	0.000333936947699979	0.00100181084309994	0.023669712774514	0.035504569161771
Psmd5	ENSMUSG00000026869	0.711240436189781	0.853801250889739	0.514300775319626	0.853801250889739	0.853801250889739	0.853801250889739
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Pck1	ENSMUSG00000027513	0.0168921052924602	0.0253381579386902	0.00755778364492933	0.022673350934788	0.514934023620345	0.514934023620345
Car13	ENSMUSG00000027555	0.853480389728993	0.853480389728993	0.399548817627028	0.853480389728993	0.853372965654504	0.853480389728993
Car2	ENSMUSG00000027562	0.514934023620345	0.706831781264721	0.706831781264721	0.706831781264721	0.444394285043028	0.706831781264721
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Acad9	ENSMUSG00000027710	0.779888212132595	0.779888212132595	0.710208797518812	0.779888212132595	0.255530331334266	0.766590994002798
Etfdh	ENSMUSG00000027809	0.926003599371282	0.926003599371282	0.92589277149125	0.926003599371282	0.115037265385284	0.345111796155853
Gmps	ENSMUSG00000027823	0.447621891168214	0.67143283675232	0.772410589885492	0.772410589885492	0.146800541856249	0.440401625568746
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Pip5k1a	ENSMUSG00000028126	0.399548817627028	0.865889271386954	0.577259514257969	0.865889271386954	1	1
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Ddah1	ENSMUSG00000028194	0.50716883916608	0.760753258749121	0.0447373296833729	0.134211989050119	0.851061028660105	0.851061028660105
Aldob	ENSMUSG00000028307	0.775217051297351	0.849805525376199	0.849805525376199	0.849805525376199	0.570836132666921	0.849805525376199
Slc35d1	ENSMUSG00000028521	0.45596561163947	0.45596561163947	0.297848640636702	0.45596561163947	0.345037391052887	0.45596561163947
Mfsd2a	ENSMUSG00000028655	1	1	0.923197812692242	1	0.643359829732651	1
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Aldh4a1	ENSMUSG00000028737	0.455625354715449	0.766645874397711	0.853049270252403	0.853049270252403	0.511097249598474	0.766645874397711
Fabp3	ENSMUSG00000028773	0.162867964743396	0.244301947115094	0.0969812105731562	0.244301947115094	0.63250023504486	0.63250023504486
Ak2	ENSMUSG00000028792	0.0766111619812296	0.229833485943689	0.283930443883615	0.425895665825422	0.710001140920767	0.710001140920767
Inpp5b	ENSMUSG00000028894	1	1	0.772767153280156	1	0.122484825003983	0.367454475011948
Prkag2	ENSMUSG00000028944	0.513665062682276	0.513665062682276	0.395928178642446	0.513665062682276	0.148772260628989	0.446316781886968
Pi4k2b	ENSMUSG00000029186	0.293293089483362	0.852940894477647	0.852940894477647	0.852940894477647	0.779888212132595	0.852940894477647
Sult1b1	ENSMUSG00000029269	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155	0.5155648232968	0.78180291566155
Hsd17b11	ENSMUSG00000029311	0.505838378028518	0.505838378028518	0.237525696869751	0.374861176998506	0.249907451332337	0.374861176998506
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Enoph1	ENSMUSG00000029326	0.456305241393103	0.684457862089655	0.453570536021945	0.684457862089655	1	1
Psph	ENSMUSG00000029446	0.570836132666921	0.706616781330066	0.706616781330066	0.706616781330066	0.345037391052887	0.706616781330066
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Aass	ENSMUSG00000029695	0.166489709738751	0.166489709738751	0.0287722902807987	0.0863168708423962	0.0642056836831391	0.0963085255247086
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Osbpl3	ENSMUSG00000029822	0.700627001620904	0.847921313356738	0.450444934184774	0.847921313356738	0.847921313356738	0.847921313356738
Itpr1	ENSMUSG00000030102	0.514934023620344	0.514934023620345	0.514934023620345	0.514934023620345	0.208156293081417	0.514934023620345
Adipor2	ENSMUSG00000030168	0.925444427431699	0.925444427431699	0.17750354896016	0.532510646880481	0.852832278580641	0.925444427431699
Cidec	ENSMUSG00000030278	0.853049270252403	0.926658283600152	0.148772260628989	0.446316781886968	0.926658283600152	0.926658283600152
Me3	ENSMUSG00000030621	0.397384062266614	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Acsm5	ENSMUSG00000030972	0.212942741031873	0.63882822309562	0.852723421673413	0.924930181917758	0.924930181917758	0.924930181917758
Slc25a14	ENSMUSG00000031105	0.709375484777034	0.926003599371282	0.926003599371282	0.926003599371282	0.711650020253571	0.926003599371282
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Slc25a15	ENSMUSG00000031482	0.0325051220296005	0.0975153660888015	0.0958690133561599	0.14380352003424	0.514934023620345	0.514934023620345
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344
Hpgd	ENSMUSG00000031613	0.17750354896016	0.520348625898199	0.926550375688041	0.926550375688041	0.346899083932133	0.520348625898199
Mbtps1	ENSMUSG00000031835	0.345037391052887	0.509798138101151	0.454600801949285	0.509798138101151	0.509798138101151	0.509798138101151
Bco2	ENSMUSG00000032066	0.853480389728993	0.926550375688041	0.926550375688041	0.926550375688041	0.577829325134931	0.926550375688041
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092
Pkm	ENSMUSG00000032294	1	1	0.342026805366747	1	0.92589277149125	1
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933
Parp16	ENSMUSG00000032392	0.643359829732651	0.643853282854191	0.400265374208516	0.643853282854191	0.643853282854191	0.643853282854191
Rbp2	ENSMUSG00000032454	0.850721744111585	0.924987846321933	0.213307944885796	0.639923834657388	0.924987846321933	0.924987846321933
Alas1	ENSMUSG00000032786	0.0451153644990944	0.135346093497283	0.327972855903274	0.49195928385491	0.774871910813158	0.774871910813158
Gde1	ENSMUSG00000033917	0.776919261684345	0.849805525376199	0.000616356194285664	0.00184906858285699	0.849805525376199	0.849805525376199
Dak	ENSMUSG00000034371	0.179945789077372	0.539837367232115	0.567818482366294	0.851727723549442	0.926003599371281	0.926003599371281
Inpp5j	ENSMUSG00000034570	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344	0.853372965654504	0.926333123228344
Gns	ENSMUSG00000034707	0.120850531362929	0.362551594088788	0.852832278580641	0.852832278580641	0.509144723230069	0.763717084845103
Neu3	ENSMUSG00000035239	0.295581119060361	0.443371678590541	0.245326864841171	0.443371678590541	0.852940894477647	0.852940894477647
Slc25a21	ENSMUSG00000035472	0.914410605267641	1	0.82682471578651	1	1	1
Xylb	ENSMUSG00000035769	0.924286968561133	0.924286968561133	0.287873078401389	0.863619235204168	0.636229315311352	0.924286968561133
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Chst12	ENSMUSG00000036599	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Psma8	ENSMUSG00000036743	0.14116671981935	0.211750079729025	0.281936405938515	0.281936405938515	0.0314025154922878	0.0942075464768635
Prodh2	ENSMUSG00000036892	0.559988304776178	0.559988304776178	0.431680053324131	0.559988304776178	0.490096264582703	0.559988304776178
Ormdl3	ENSMUSG00000038150	0.0451153644990944	0.135346093497283	0.174692232033629	0.262038348050444	0.852832278580641	0.852832278580641
Slc19a3	ENSMUSG00000038496	0.41848462695615	0.775217051297351	0.633039971999413	0.775217051297351	0.775217051297351	0.775217051297351
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Pdk2	ENSMUSG00000038967	0.710001140920767	0.781170242226513	0.0958690133561599	0.28760704006848	0.781170242226513	0.781170242226513
Adk	ENSMUSG00000039197	0.515564823296801	0.773347234945201	0.255530331334266	0.766590994002797	0.78180291566155	0.78180291566155
Dse	ENSMUSG00000039497	0.295581119060361	0.297095062262362	0.146800541856249	0.297095062262362	0.297095062262362	0.297095062262362
Mocos	ENSMUSG00000039616	0.180293335960318	0.540880007880955	0.7802108304765	0.851954599472143	0.851954599472143	0.851954599472143
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Spns2	ENSMUSG00000040447	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886967	0.505838378028518	0.514934023620345
Bbox1	ENSMUSG00000041660	0.321747661812897	0.321747661812897	0.0834655302699765	0.250396590809929	0.220723922642366	0.321747661812897
Osbpl6	ENSMUSG00000042359	0.501782052576058	0.752673078864087	0.852940894477647	0.852940894477647	0.390750658104794	0.752673078864087
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Acot6	ENSMUSG00000043487	0.851732715229127	0.851732715229127	0.214037080764326	0.642111242292977	0.577259514257969	0.851732715229127
Osbpl1a	ENSMUSG00000044252	0.0101222094973346	0.0303666284920038	0.348008842235184	0.522013263352776	0.926550375688041	0.926550375688041
Tnfaip8l1	ENSMUSG00000044469	0.347639524025037	0.679320738524319	0.711650020253571	0.711650020253571	0.452880492349546	0.679320738524319
Liph	ENSMUSG00000044626	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.577829325134931	0.642864324224729
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Stard5	ENSMUSG00000046027	0.926550375688041	0.926550375688041	0.513665062682276	0.926550375688041	0.926550375688041	0.926550375688041
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Sephs2	ENSMUSG00000049091	0.0321889748775513	0.0482834623163269	0.0129100470219435	0.0387301410658306	0.694011247640131	0.694011247640131
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Agmo	ENSMUSG00000050103	0.211844580334808	0.635533741004424	0.511097249598474	0.642366752097095	0.642366752097095	0.642366752097095
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Gnpda1	ENSMUSG00000052102	0.345410946355104	0.926550375688041	0.926550375688041	0.926550375688041	0.711650020253571	0.926550375688041
Mogat2	ENSMUSG00000052396	0.118714930081337	0.35614479024401	0.300095920620218	0.450143880930327	0.578113371816017	0.578113371816017
Mat2a	ENSMUSG00000053907	0.452880492349546	0.679320738524319	0.0908536824179312	0.272561047253794	0.9255572759333	0.9255572759333
Ndst1	ENSMUSG00000054008	0.450094379653806	0.675141569480709	0.851732715229127	0.851732715229127	0.144820068500793	0.43446020550238
Fabp1	ENSMUSG00000054422	0.779888212132595	0.779888212132595	0.120850531362929	0.362551594088788	0.392985378348026	0.589478067522039
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
B4galt6	ENSMUSG00000056124	0.578113371816017	0.867170057724026	0.0164739112492867	0.0494217337478601	0.926441990075769	0.926441990075769
Acbd4	ENSMUSG00000056938	0.299349060054895	0.449023590082343	0.0451153644990944	0.135346093497283	0.926441990075769	0.926441990075769
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Gda	ENSMUSG00000058624	0.576973746230334	0.865460619345501	0.575824878403157	0.865460619345501	0.926333123228344	0.926333123228344
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Ddhd2	ENSMUSG00000061313	0.782117202022501	0.853694531487825	0.853694531487825	0.853694531487825	0.78180291566155	0.853694531487825
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931
Eno1	ENSMUSG00000063524	0.853372965654504	0.853372965654504	0.0969812105731562	0.145471815859734	0.0566379395854604	0.145471815859734
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833
mt-Nd6	ENSMUSG00000064368	0.216214347033995	0.5155648232968	0.5155648232968	0.5155648232968	0.511097249598474	0.5155648232968
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Impad1	ENSMUSG00000066324	0.17610058307789	0.264150874616835	0.138156294413154	0.264150874616835	0.635703516568382	0.635703516568382
Mfsd7b	ENSMUSG00000066595	0.576112968612194	0.576973746230334	0.575824878403157	0.576973746230334	0.576973746230334	0.576973746230334
Vkorc1l1	ENSMUSG00000066735	0.641867098978197	0.641867098978197	0.573791743469336	0.641867098978197	0.640861491578951	0.641867098978197
Gng5	ENSMUSG00000068523	0.5155648232968	0.577829325134931	0.577829325134931	0.577829325134931	0.346527959006435	0.577829325134931
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724
Marc2	ENSMUSG00000073481	0.570836132666921	0.570836132666921	0.0497293992720784	0.149188197816235	0.570836132666921	0.570836132666921
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Amd1	ENSMUSG00000075232	0.781170242226513	0.781170242226513	0.451840588205062	0.781170242226513	0.711854160331342	0.781170242226513
Psme3	ENSMUSG00000078652	0.853372965654504	0.853480389728993	0.853480389728993	0.853480389728993	0.78180291566155	0.853480389728993
Cyp4v3	ENSMUSG00000079057	0.78148726569172	0.926550375688041	0.853801250889739	0.926550375688041	0.926550375688041	0.926550375688041
Neu2	ENSMUSG00000079434	0.392243127063687	0.588364690595531	0.190629863394776	0.571889590184328	0.92356607045265	0.92356607045265
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

Download data as csv

Metabolism of lipids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Pla1a	ENSMUSG00000002847	0.119631084167591	0.323235417174495	0.21549027811633	0.323235417174495	0.578113371816017	0.578113371816017
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Cyp17a1	ENSMUSG00000003555	0.0751163767602349	0.225349130280705	0.515249728559994	0.515249728559994	0.45149265530335	0.515249728559994
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Lpcat3	ENSMUSG00000004270	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739	0.853801250889739	0.853801250889739
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
B4galnt1	ENSMUSG00000006731	0.853372965654504	0.853694531487825	0.18064054691103	0.541921640733091	0.853694531487825	0.853694531487825
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Neu1	ENSMUSG00000007038	0.926333123228344	0.926333123228344	0.575536202757516	0.863304304136274	0.514300775319626	0.863304304136274
Hmgcll1	ENSMUSG00000007908	0.397384062266614	0.7802108304765	0.643359829732651	0.7802108304765	0.7802108304765	0.7802108304765
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Tnfaip8l2	ENSMUSG00000013707	0.122484825003983	0.367454475011948	0.850151080737202	0.850151080737202	0.62976545519988	0.850151080737202
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Mtmr4	ENSMUSG00000018401	0.254414773803597	0.639337105615665	0.454600801949285	0.639337105615665	0.639337105615665	0.639337105615665
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Dpep1	ENSMUSG00000019278	0.211110344399808	0.633331033199424	0.567513221841557	0.851269832762335	1	1
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Fabp6	ENSMUSG00000020405	0.757910339741814	0.919766116387509	0.346871613920738	0.919766116387509	0.919766116387509	0.919766116387509
Arsg	ENSMUSG00000020604	0.922445041430936	0.922445041430936	0.0718551089340876	0.215565326802263	0.467009962776288	0.700514944164432
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Acot12	ENSMUSG00000021620	0.851732715229127	0.926550375688041	0.641867098978198	0.926550375688041	0.926550375688041	0.926550375688041
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Samd8	ENSMUSG00000021770	0.290984282074805	0.5155648232968	0.5155648232968	0.5155648232968	0.450794830295118	0.5155648232968
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Arsa	ENSMUSG00000022620	0.347639524025037	0.454258017332816	0.177153312234059	0.454258017332816	0.454258017332816	0.454258017332816
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Asah2	ENSMUSG00000024887	0.711854160331342	0.711854160331342	0.578113371816017	0.711854160331342	0.514934023620344	0.711854160331342
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Gyk	ENSMUSG00000025059	0.0741204440774082	0.11155406640886	0.144157978128026	0.144157978128026	0.0743693776059064	0.11155406640886
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Scd2	ENSMUSG00000025203	0.569937449249116	0.569937449249116	0.147458757705094	0.442376273115283	0.389247465657472	0.569937449249116
Acot9	ENSMUSG00000025287	0.343537039781257	0.590587491403246	0.393724994268831	0.590587491403246	0.779888212132595	0.779888212132595
Lpgat1	ENSMUSG00000026623	1	1	0.926003599371282	1	0.57113445032749	1
Acbd7	ENSMUSG00000026644	0.231130630776632	0.231130630776632	0.231130630776632	0.231130630776632	0.0680278868695481	0.204083660608644
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Fam73b	ENSMUSG00000026858	0.575824878403157	0.575824878403157	0.000333936947699979	0.00100181084309994	0.023669712774514	0.035504569161771
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Pip5k1a	ENSMUSG00000028126	0.399548817627028	0.865889271386954	0.577259514257969	0.865889271386954	1	1
Mfsd2a	ENSMUSG00000028655	1	1	0.923197812692242	1	0.643359829732651	1
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Fabp3	ENSMUSG00000028773	0.162867964743396	0.244301947115094	0.0969812105731562	0.244301947115094	0.63250023504486	0.63250023504486
Prkag2	ENSMUSG00000028944	0.513665062682276	0.513665062682276	0.395928178642446	0.513665062682276	0.148772260628989	0.446316781886968
Pi4k2b	ENSMUSG00000029186	0.293293089483362	0.852940894477647	0.852940894477647	0.852940894477647	0.779888212132595	0.852940894477647
Hsd17b11	ENSMUSG00000029311	0.505838378028518	0.505838378028518	0.237525696869751	0.374861176998506	0.249907451332337	0.374861176998506
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Osbpl3	ENSMUSG00000029822	0.700627001620904	0.847921313356738	0.450444934184774	0.847921313356738	0.847921313356738	0.847921313356738
Cidec	ENSMUSG00000030278	0.853049270252403	0.926658283600152	0.148772260628989	0.446316781886968	0.926658283600152	0.926658283600152
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344
Hpgd	ENSMUSG00000031613	0.17750354896016	0.520348625898199	0.926550375688041	0.926550375688041	0.346899083932133	0.520348625898199
Mbtps1	ENSMUSG00000031835	0.345037391052887	0.509798138101151	0.454600801949285	0.509798138101151	0.509798138101151	0.509798138101151
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933
Gde1	ENSMUSG00000033917	0.776919261684345	0.849805525376199	0.000616356194285664	0.00184906858285699	0.849805525376199	0.849805525376199
Inpp5j	ENSMUSG00000034570	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344	0.853372965654504	0.926333123228344
Neu3	ENSMUSG00000035239	0.295581119060361	0.443371678590541	0.245326864841171	0.443371678590541	0.852940894477647	0.852940894477647
Ormdl3	ENSMUSG00000038150	0.0451153644990944	0.135346093497283	0.174692232033629	0.262038348050444	0.852832278580641	0.852832278580641
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Spns2	ENSMUSG00000040447	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886967	0.505838378028518	0.514934023620345
Osbpl6	ENSMUSG00000042359	0.501782052576058	0.752673078864087	0.852940894477647	0.852940894477647	0.390750658104794	0.752673078864087
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Acot6	ENSMUSG00000043487	0.851732715229127	0.851732715229127	0.214037080764326	0.642111242292977	0.577259514257969	0.851732715229127
Osbpl1a	ENSMUSG00000044252	0.0101222094973346	0.0303666284920038	0.348008842235184	0.522013263352776	0.926550375688041	0.926550375688041
Tnfaip8l1	ENSMUSG00000044469	0.347639524025037	0.679320738524319	0.711650020253571	0.711650020253571	0.452880492349546	0.679320738524319
Liph	ENSMUSG00000044626	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.577829325134931	0.642864324224729
Stard5	ENSMUSG00000046027	0.926550375688041	0.926550375688041	0.513665062682276	0.926550375688041	0.926550375688041	0.926550375688041
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Agmo	ENSMUSG00000050103	0.211844580334808	0.635533741004424	0.511097249598474	0.642366752097095	0.642366752097095	0.642366752097095
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Mogat2	ENSMUSG00000052396	0.118714930081337	0.35614479024401	0.300095920620218	0.450143880930327	0.578113371816017	0.578113371816017
Fabp1	ENSMUSG00000054422	0.779888212132595	0.779888212132595	0.120850531362929	0.362551594088788	0.392985378348026	0.589478067522039
Acbd4	ENSMUSG00000056938	0.299349060054895	0.449023590082343	0.0451153644990944	0.135346093497283	0.926441990075769	0.926441990075769
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Ddhd2	ENSMUSG00000061313	0.782117202022501	0.853694531487825	0.853694531487825	0.853694531487825	0.78180291566155	0.853694531487825
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724
Neu2	ENSMUSG00000079434	0.392243127063687	0.588364690595531	0.190629863394776	0.571889590184328	0.92356607045265	0.92356607045265
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Biological oxidations

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Comt	ENSMUSG00000000326	1	1	0.21549027811633	0.64647083434899	0.640355507848752	0.960533261773128
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
Cyb5r3	ENSMUSG00000018042	0.255901190956604	0.383851786434905	0.170434860179341	0.383851786434905	0.92589277149125	0.92589277149125
Dpep1	ENSMUSG00000019278	0.211110344399808	0.633331033199424	0.567513221841557	0.851269832762335	1	1
Oplah	ENSMUSG00000022562	0.45596561163947	0.683948417459205	0.215127611919161	0.645382835757484	0.853694531487825	0.853694531487825
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Acy3	ENSMUSG00000024866	0.853372965654504	0.853372965654504	0.118409250205154	0.355227750615461	0.78180291566155	0.853372965654504
Bpnt1	ENSMUSG00000026617	0.293293089483362	0.439939634225043	1	1	0.261555237955603	0.439939634225043
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Slc35d1	ENSMUSG00000028521	0.45596561163947	0.45596561163947	0.297848640636702	0.45596561163947	0.345037391052887	0.45596561163947
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Sult1b1	ENSMUSG00000029269	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155	0.5155648232968	0.78180291566155
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Acsm5	ENSMUSG00000030972	0.212942741031873	0.63882822309562	0.852723421673413	0.924930181917758	0.924930181917758	0.924930181917758
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Mat2a	ENSMUSG00000053907	0.452880492349546	0.679320738524319	0.0908536824179312	0.272561047253794	0.9255572759333	0.9255572759333
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Impad1	ENSMUSG00000066324	0.17610058307789	0.264150874616835	0.138156294413154	0.264150874616835	0.635703516568382	0.635703516568382
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Marc2	ENSMUSG00000073481	0.570836132666921	0.570836132666921	0.0497293992720784	0.149188197816235	0.570836132666921	0.570836132666921
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Cyp4v3	ENSMUSG00000079057	0.78148726569172	0.926550375688041	0.853801250889739	0.926550375688041	0.926550375688041	0.926550375688041
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Transport of small molecules

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Sri	ENSMUSG00000003161	0.11810342389482	0.255901190956604	0.255901190956604	0.255901190956604	0.255530331334266	0.255901190956604
Pex19	ENSMUSG00000003464	0.148115998140415	0.222173997210623	0.0958690133561599	0.222173997210623	0.513665062682276	0.513665062682276
Clcn5	ENSMUSG00000004317	0.146141353215796	0.438424059647387	0.643359829732651	0.852504981253341	0.852504981253341	0.852504981253341
Slc2a9	ENSMUSG00000005107	0.392243127063687	0.395928178642446	0.392985378348026	0.395928178642446	0.395928178642446	0.395928178642446
Slc1a3	ENSMUSG00000005360	0.781960228679124	0.926387617028817	0.781960228679124	0.926387617028817	0.926387617028817	0.926387617028817
Atp7b	ENSMUSG00000006567	0.443306001726869	0.443306001726869	0.0303111090728679	0.0909333272186038	0.283134662157423	0.424701993236134
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Slc3a2	ENSMUSG00000010095	0.148115998140416	0.375428758901986	0.250285839267991	0.375428758901986	0.778911768167544	0.778911768167544
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Slc12a7	ENSMUSG00000017756	0.214037080764326	0.642111242292977	0.851732715229127	0.851732715229127	0.57113445032749	0.851732715229127
Sgk2	ENSMUSG00000017868	0.926658283600152	0.926658283600152	0.514300775319626	0.926658283600152	0.926658283600152	0.926658283600152
Mb	ENSMUSG00000018893	0.773122046545957	0.773122046545957	0.398108175780842	0.742194177351434	0.494796118234289	0.742194177351434
Slc25a22	ENSMUSG00000019082	0.642366752097095	0.643359829732651	0.34837756124189	0.643359829732651	0.643359829732651	0.643359829732651
Slc16a10	ENSMUSG00000019838	0.563485358844814	0.563485358844814	0.297095062262362	0.563485358844814	0.393724994268831	0.563485358844814
Slc5a8	ENSMUSG00000020062	0.762507504068942	0.762507504068942	0.00700808200338927	0.0210242460101678	0.246861959455465	0.370292939183197
Slc36a1	ENSMUSG00000020261	0.237525696869751	0.712577090609252	1	1	0.576973746230334	0.865460619345501
Slc22a4	ENSMUSG00000020334	0.511742979522636	0.853801250889739	0.643853282854191	0.853801250889739	0.853801250889739	0.853801250889739
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Slc46a1	ENSMUSG00000020829	0.283134662157423	0.424701993236134	0.0520308460244811	0.156092538073443	0.553410011703054	0.553410011703054
Slc6a3	ENSMUSG00000021609	0.335836366668576	0.337653038060633	0.335836366668576	0.337653038060633	0.337653038060633	0.337653038060633
Psmd6	ENSMUSG00000021737	0.78180291566155	0.92622377157404	0.779238691542963	0.92622377157404	0.92622377157404	0.92622377157404
Slc7a8	ENSMUSG00000022180	0.573791743469336	0.780851835278818	0.21549027811633	0.64647083434899	0.780851835278818	0.780851835278818
Apod	ENSMUSG00000022548	0.777755996383525	0.850948190971883	0.850948190971883	0.850948190971883	0.0197144755306785	0.0591434265920354
Tfrc	ENSMUSG00000022797	0.180293335960318	0.540880007880954	0.926003599371281	0.926003599371281	0.710001140920767	0.926003599371281
Soat2	ENSMUSG00000023045	0.216214347033995	0.648643041101984	1	1	0.710208797518812	1
Abcg8	ENSMUSG00000024254	0.297848640636702	0.710001140920767	0.710001140920767	0.710001140920767	0.640355507848752	0.710001140920767
Afg3l2	ENSMUSG00000024527	0.454942951775342	0.455625354715448	0.455625354715448	0.455625354715448	0.148115998140416	0.444347994421247
Trpm6	ENSMUSG00000024727	0.346899083932133	0.513026869856283	0.205174703261494	0.513026869856283	0.513026869856283	0.513026869856283
Lipa	ENSMUSG00000024781	0.633039971999413	0.923443907074248	0.162867964743396	0.488603894230187	0.923443907074248	0.923443907074248
Slc1a1	ENSMUSG00000024935	0.76875013537822	0.919906712313455	0.919906712313455	0.919906712313455	0.11810342389482	0.354310271684459
P4hb	ENSMUSG00000025130	0.7802108304765	0.7802108304765	0.329176790045262	0.7802108304765	0.709375484777034	0.7802108304765
Abcc2	ENSMUSG00000025194	0.45596561163947	0.683948417459205	0.348008842235184	0.683948417459205	0.781170242226513	0.781170242226513
Slc15a1	ENSMUSG00000025557	0.711240436189781	0.926658283600152	0.643359829732651	0.926658283600152	0.926658283600152	0.926658283600152
Slc28a1	ENSMUSG00000025726	0.255901190956604	0.256271555563966	0.00161470887631957	0.0048441266289587	0.256271555563966	0.256271555563966
Psmd5	ENSMUSG00000026869	0.711240436189781	0.853801250889739	0.514300775319626	0.853801250889739	0.853801250889739	0.853801250889739
Car2	ENSMUSG00000027562	0.514934023620345	0.706831781264721	0.706831781264721	0.706831781264721	0.444394285043028	0.706831781264721
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Nceh1	ENSMUSG00000027698	0.148772260628989	0.148772260628989	0.00253244992826164	0.00759734978478493	0.0488765001588118	0.0733147502382177
Abcd3	ENSMUSG00000028127	0.853907737111068	0.853907737111068	0.177153312234059	0.531459936702178	0.853907737111068	0.853907737111068
Mttp	ENSMUSG00000028158	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.7802108304765	0.781170242226513
Slc35a1	ENSMUSG00000028293	0.852832278580641	0.852832278580641	0.255901190956604	0.767703572869812	0.779888212132595	0.852832278580641
Slc35d1	ENSMUSG00000028521	0.45596561163947	0.45596561163947	0.297848640636702	0.45596561163947	0.345037391052887	0.45596561163947
Abcb9	ENSMUSG00000029408	0.266267359102332	0.399401038653498	7.32463150534408e-05	0.000219738945160323	1	1
Slc13a1	ENSMUSG00000029700	0.286303237509396	0.429454856264095	0.167569692867574	0.429454856264095	0.923443907074248	0.923443907074248
Slc5a11	ENSMUSG00000030769	0.146800541856249	0.260448650831748	0.173632433887832	0.260448650831748	0.708745765211584	0.708745765211584
Slc38a5	ENSMUSG00000031170	0.343537039781257	0.343537039781257	0.0741204440774081	0.222361332232224	0.249528554620971	0.343537039781257
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Slc12a3	ENSMUSG00000031766	0.701310685803632	0.701310685803632	0.0706396252934259	0.105959437940139	0.0212382357534491	0.0637147072603474
Apoa5	ENSMUSG00000032079	0.708323672944427	0.708323672944427	0.0168921052924601	0.0506763158773803	0.513026869856283	0.708323672944427
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092
Aqp9	ENSMUSG00000032204	0.11810342389482	0.177155135842229	0.92589277149125	0.92589277149125	0.00649065913668484	0.0194719774100545
Atp1a1	ENSMUSG00000033161	0.148772260628989	0.223158390943483	0.141500034183268	0.223158390943483	0.925669613555092	0.925669613555092
Parl	ENSMUSG00000033918	0.34837756124189	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Ttyh2	ENSMUSG00000034714	0.0575107614292584	0.172532284287775	0.77858338846904	0.77858338846904	0.569937449249116	0.77858338846904
Slc9a3	ENSMUSG00000036123	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504
Slc2a13	ENSMUSG00000036298	0.78148726569172	0.78180291566155	0.511742979522636	0.78180291566155	0.78180291566155	0.78180291566155
Psma8	ENSMUSG00000036743	0.14116671981935	0.211750079729025	0.281936405938515	0.281936405938515	0.0314025154922878	0.0942075464768635
Mcoln3	ENSMUSG00000036853	0.838755433459624	0.844188605458011	0.844188605458011	0.844188605458011	0.532921583121457	0.844188605458011
Atp11b	ENSMUSG00000037400	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993	0.782117202022501	0.853480389728993
Slc30a1	ENSMUSG00000037434	0.642366752097095	0.642366752097095	0.0753654386865988	0.226096316059796	0.576973746230334	0.642366752097095
Slc43a2	ENSMUSG00000038178	0.0441715176243984	0.132514552873195	0.398108175780842	0.597162263671263	1	1
Asic3	ENSMUSG00000038276	0.578113371816017	0.643853282854191	0.00468160475316411	0.0140448142594923	0.643853282854191	0.643853282854191
Micu3	ENSMUSG00000039478	0.455625354715449	0.853372965654504	0.853372965654504	0.853372965654504	0.781960228679124	0.853372965654504
Fbxl5	ENSMUSG00000039753	0.926658283600152	1	1	1	0.254787123615605	0.764361370846816
Abcg5	ENSMUSG00000040505	0.643359829732651	0.78180291566155	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155
Abcb1a	ENSMUSG00000040584	0.11993617140438	0.179904257106569	0.024062085667391	0.0721862570021729	0.216214347033995	0.216214347033995
Wnk3	ENSMUSG00000041245	0.0958690133561599	0.28760704006848	0.297095062262362	0.445642593393544	0.710416009055326	0.710416009055326
Cftr	ENSMUSG00000041301	0.0969812105731562	0.290943631719469	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095
Slc5a12	ENSMUSG00000041644	1	1	0.926658283600152	1	0.926658283600152	1
Slc24a4	ENSMUSG00000041771	0.505169133438821	0.637793186752488	0.227062445905894	0.637793186752488	0.637793186752488	0.637793186752488
Aqp11	ENSMUSG00000042797	0.45596561163947	1	0.711650020253571	1	1	1
Pcsk9	ENSMUSG00000044254	0.926003599371281	0.926333123228344	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344
Lrrc8d	ENSMUSG00000046079	0.399548817627028	1	0.926333123228344	1	1	1
Slc17a5	ENSMUSG00000049624	0.576973746230334	0.576973746230334	0.456305241393103	0.576973746230334	0.442211413534162	0.576973746230334
Slc29a4	ENSMUSG00000050822	0.710208797518812	0.852175490580835	0.148115998140416	0.444347994421247	0.852175490580835	0.852175490580835
Slc27a4	ENSMUSG00000059316	0.255901190956604	0.383851786434906	0.243396309647537	0.383851786434906	0.511097249598474	0.511097249598474
Ap2a1	ENSMUSG00000060279	0.395196379647461	0.566593564630738	0.566593564630738	0.566593564630738	0.12935516793705	0.388065503811151
Nr1h2	ENSMUSG00000060601	0.215127611919161	0.322691417878742	1	1	0.202543053799149	0.322691417878742
Ano6	ENSMUSG00000064210	0.578113371816017	0.867170057724026	0.400265374208515	0.867170057724026	0.926441990075769	0.926441990075769
Mfsd7b	ENSMUSG00000066595	0.576112968612194	0.576973746230334	0.575824878403157	0.576973746230334	0.576973746230334	0.576973746230334
Slc4a5	ENSMUSG00000068323	0.690028363829288	0.690028363829288	0.379206615039809	0.568809922559714	0.224181550151583	0.568809922559714
Gng5	ENSMUSG00000068523	0.5155648232968	0.577829325134931	0.577829325134931	0.577829325134931	0.346527959006435	0.577829325134931
Slc17a7	ENSMUSG00000070570	0.926604389137101	0.926604389137101	0.641616487517698	0.926604389137101	0.394829509482604	0.926604389137101
Ddi2	ENSMUSG00000078515	0.853372965654504	0.853372965654504	0.297848640636702	0.513607944031322	0.342405296020881	0.513607944031322
Psme3	ENSMUSG00000078652	0.853372965654504	0.853480389728993	0.853480389728993	0.853480389728993	0.78180291566155	0.853480389728993
Slc5a3	ENSMUSG00000089774	0.177153312234059	0.531459936702176	0.642366752097095	0.853694531487825	0.853694531487825	0.853694531487825

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Peroxisomal lipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Acot6	ENSMUSG00000043487	0.851732715229127	0.851732715229127	0.214037080764326	0.642111242292977	0.577259514257969	0.851732715229127
Acbd4	ENSMUSG00000056938	0.299349060054895	0.449023590082343	0.0451153644990944	0.135346093497283	0.926441990075769	0.926441990075769

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Fatty acid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Dpep1	ENSMUSG00000019278	0.211110344399808	0.633331033199424	0.567513221841557	0.851269832762335	1	1
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Acot12	ENSMUSG00000021620	0.851732715229127	0.926550375688041	0.641867098978198	0.926550375688041	0.926550375688041	0.926550375688041
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Acsl5	ENSMUSG00000024981	0.926550375688041	1	0.711854160331342	1	1	1
Scd2	ENSMUSG00000025203	0.569937449249116	0.569937449249116	0.147458757705094	0.442376273115283	0.389247465657472	0.569937449249116
Acot9	ENSMUSG00000025287	0.343537039781257	0.590587491403246	0.393724994268831	0.590587491403246	0.779888212132595	0.779888212132595
Acbd7	ENSMUSG00000026644	0.231130630776632	0.231130630776632	0.231130630776632	0.231130630776632	0.0680278868695481	0.204083660608644
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Hadh	ENSMUSG00000027984	0.118409250205154	0.17761387530773	0.0211129141819613	0.063338742545884	0.851061028660105	0.851061028660105
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Prkag2	ENSMUSG00000028944	0.513665062682276	0.513665062682276	0.395928178642446	0.513665062682276	0.148772260628989	0.446316781886968
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933
Acot6	ENSMUSG00000043487	0.851732715229127	0.851732715229127	0.214037080764326	0.642111242292977	0.577259514257969	0.851732715229127
Cbr1	ENSMUSG00000051483	0.511742979522635	0.767614469283952	0.0116270609405239	0.0348811828215717	0.776919261684345	0.776919261684345
Acbd4	ENSMUSG00000056938	0.299349060054895	0.449023590082343	0.0451153644990944	0.135346093497283	0.926441990075769	0.926441990075769
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854

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Metabolism of steroids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Cyp17a1	ENSMUSG00000003555	0.0751163767602349	0.225349130280705	0.515249728559994	0.515249728559994	0.45149265530335	0.515249728559994
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
Fabp6	ENSMUSG00000020405	0.757910339741814	0.919766116387509	0.346871613920738	0.919766116387509	0.919766116387509	0.919766116387509
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Hsd17b11	ENSMUSG00000029311	0.505838378028518	0.505838378028518	0.237525696869751	0.374861176998506	0.249907451332337	0.374861176998506
Osbpl3	ENSMUSG00000029822	0.700627001620904	0.847921313356738	0.450444934184774	0.847921313356738	0.847921313356738	0.847921313356738
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344
Mbtps1	ENSMUSG00000031835	0.345037391052887	0.509798138101151	0.454600801949285	0.509798138101151	0.509798138101151	0.509798138101151
Osbpl6	ENSMUSG00000042359	0.501782052576058	0.752673078864087	0.852940894477647	0.852940894477647	0.390750658104794	0.752673078864087
Osbpl1a	ENSMUSG00000044252	0.0101222094973346	0.0303666284920038	0.348008842235184	0.522013263352776	0.926550375688041	0.926550375688041
Stard5	ENSMUSG00000046027	0.926550375688041	0.926550375688041	0.513665062682276	0.926550375688041	0.926550375688041	0.926550375688041
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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Cholesterol biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Mvd	ENSMUSG00000006517	0.342026805366747	0.853801250889739	0.853801250889739	0.853801250889739	0.576112968612194	0.853801250889739
Fdft1	ENSMUSG00000021273	0.138156294413154	0.414468883239461	0.293293089483362	0.439939634225043	0.631413595275176	0.631413595275176
Sqle	ENSMUSG00000022351	0.563485358844814	0.776919261684345	0.252920381501207	0.75876114450362	0.776919261684345	0.776919261684345
Acat2	ENSMUSG00000023832	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333	0.775217051297351	0.9255572759333
Tm7sf2	ENSMUSG00000024799	0.706616781330066	1	0.575824878403157	1	1	1
Pmvk	ENSMUSG00000027952	0.397384062266614	0.707899741868332	0.643853282854191	0.707899741868332	0.707899741868332	0.707899741868332
Nsdhl	ENSMUSG00000031349	0.0575107614292584	0.0862661421438876	0.0382382535564792	0.0862661421438876	0.171859370212435	0.171859370212435
Sc4mol	ENSMUSG00000031604	0.117185073436597	0.351555220309791	0.926333123228344	0.926333123228344	0.776243028387552	0.926333123228344
Fdps	ENSMUSG00000059743	0.634645058916812	0.634645058916812	0.297848640636702	0.634645058916812	0.565047747060087	0.634645058916812
Hmgcs1	ENSMUSG00000093930	0.246478961478169	0.511742979522636	0.511742979522636	0.511742979522636	0.505838378028518	0.511742979522636

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SLC-mediated transmembrane transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sri	ENSMUSG00000003161	0.11810342389482	0.255901190956604	0.255901190956604	0.255901190956604	0.255530331334266	0.255901190956604
Slc2a9	ENSMUSG00000005107	0.392243127063687	0.395928178642446	0.392985378348026	0.395928178642446	0.395928178642446	0.395928178642446
Slc1a3	ENSMUSG00000005360	0.781960228679124	0.926387617028817	0.781960228679124	0.926387617028817	0.926387617028817	0.926387617028817
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Slc3a2	ENSMUSG00000010095	0.148115998140416	0.375428758901986	0.250285839267991	0.375428758901986	0.778911768167544	0.778911768167544
Slc12a7	ENSMUSG00000017756	0.214037080764326	0.642111242292977	0.851732715229127	0.851732715229127	0.57113445032749	0.851732715229127
Slc25a22	ENSMUSG00000019082	0.642366752097095	0.643359829732651	0.34837756124189	0.643359829732651	0.643359829732651	0.643359829732651
Slc16a10	ENSMUSG00000019838	0.563485358844814	0.563485358844814	0.297095062262362	0.563485358844814	0.393724994268831	0.563485358844814
Slc5a8	ENSMUSG00000020062	0.762507504068942	0.762507504068942	0.00700808200338927	0.0210242460101678	0.246861959455465	0.370292939183197
Slc36a1	ENSMUSG00000020261	0.237525696869751	0.712577090609252	1	1	0.576973746230334	0.865460619345501
Slc22a4	ENSMUSG00000020334	0.511742979522636	0.853801250889739	0.643853282854191	0.853801250889739	0.853801250889739	0.853801250889739
Slc6a3	ENSMUSG00000021609	0.335836366668576	0.337653038060633	0.335836366668576	0.337653038060633	0.337653038060633	0.337653038060633
Slc7a8	ENSMUSG00000022180	0.573791743469336	0.780851835278818	0.21549027811633	0.64647083434899	0.780851835278818	0.780851835278818
Apod	ENSMUSG00000022548	0.777755996383525	0.850948190971883	0.850948190971883	0.850948190971883	0.0197144755306785	0.0591434265920354
Slc1a1	ENSMUSG00000024935	0.76875013537822	0.919906712313455	0.919906712313455	0.919906712313455	0.11810342389482	0.354310271684459
Slc15a1	ENSMUSG00000025557	0.711240436189781	0.926658283600152	0.643359829732651	0.926658283600152	0.926658283600152	0.926658283600152
Slc28a1	ENSMUSG00000025726	0.255901190956604	0.256271555563966	0.00161470887631957	0.0048441266289587	0.256271555563966	0.256271555563966
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Slc35a1	ENSMUSG00000028293	0.852832278580641	0.852832278580641	0.255901190956604	0.767703572869812	0.779888212132595	0.852832278580641
Slc35d1	ENSMUSG00000028521	0.45596561163947	0.45596561163947	0.297848640636702	0.45596561163947	0.345037391052887	0.45596561163947
Slc13a1	ENSMUSG00000029700	0.286303237509396	0.429454856264095	0.167569692867574	0.429454856264095	0.923443907074248	0.923443907074248
Slc5a11	ENSMUSG00000030769	0.146800541856249	0.260448650831748	0.173632433887832	0.260448650831748	0.708745765211584	0.708745765211584
Slc38a5	ENSMUSG00000031170	0.343537039781257	0.343537039781257	0.0741204440774081	0.222361332232224	0.249528554620971	0.343537039781257
Slc12a3	ENSMUSG00000031766	0.701310685803632	0.701310685803632	0.0706396252934259	0.105959437940139	0.0212382357534491	0.0637147072603474
Slc9a3	ENSMUSG00000036123	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504
Slc2a13	ENSMUSG00000036298	0.78148726569172	0.78180291566155	0.511742979522636	0.78180291566155	0.78180291566155	0.78180291566155
Slc30a1	ENSMUSG00000037434	0.642366752097095	0.642366752097095	0.0753654386865988	0.226096316059796	0.576973746230334	0.642366752097095
Slc43a2	ENSMUSG00000038178	0.0441715176243984	0.132514552873195	0.398108175780842	0.597162263671263	1	1
Slc5a12	ENSMUSG00000041644	1	1	0.926658283600152	1	0.926658283600152	1
Slc24a4	ENSMUSG00000041771	0.505169133438821	0.637793186752488	0.227062445905894	0.637793186752488	0.637793186752488	0.637793186752488
Slc17a5	ENSMUSG00000049624	0.576973746230334	0.576973746230334	0.456305241393103	0.576973746230334	0.442211413534162	0.576973746230334
Slc29a4	ENSMUSG00000050822	0.710208797518812	0.852175490580835	0.148115998140416	0.444347994421247	0.852175490580835	0.852175490580835
Slc27a4	ENSMUSG00000059316	0.255901190956604	0.383851786434906	0.243396309647537	0.383851786434906	0.511097249598474	0.511097249598474
Slc4a5	ENSMUSG00000068323	0.690028363829288	0.690028363829288	0.379206615039809	0.568809922559714	0.224181550151583	0.568809922559714
Slc17a7	ENSMUSG00000070570	0.926604389137101	0.926604389137101	0.641616487517698	0.926604389137101	0.394829509482604	0.926604389137101
Ddi2	ENSMUSG00000078515	0.853372965654504	0.853372965654504	0.297848640636702	0.513607944031322	0.342405296020881	0.513607944031322
Slc5a3	ENSMUSG00000089774	0.177153312234059	0.531459936702176	0.642366752097095	0.853694531487825	0.853694531487825	0.853694531487825

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Glycerophospholipid biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Pla1a	ENSMUSG00000002847	0.119631084167591	0.323235417174495	0.21549027811633	0.323235417174495	0.578113371816017	0.578113371816017
Lpcat3	ENSMUSG00000004270	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739	0.853801250889739	0.853801250889739
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Lpgat1	ENSMUSG00000026623	1	1	0.926003599371282	1	0.57113445032749	1
Fam73b	ENSMUSG00000026858	0.575824878403157	0.575824878403157	0.000333936947699979	0.00100181084309994	0.023669712774514	0.035504569161771
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Mfsd2a	ENSMUSG00000028655	1	1	0.923197812692242	1	0.643359829732651	1
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Liph	ENSMUSG00000044626	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.577829325134931	0.642864324224729
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Ddhd2	ENSMUSG00000061313	0.782117202022501	0.853694531487825	0.853694531487825	0.853694531487825	0.78180291566155	0.853694531487825
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724

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Sphingolipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
B4galnt1	ENSMUSG00000006731	0.853372965654504	0.853694531487825	0.18064054691103	0.541921640733091	0.853694531487825	0.853694531487825
Neu1	ENSMUSG00000007038	0.926333123228344	0.926333123228344	0.575536202757516	0.863304304136274	0.514300775319626	0.863304304136274
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Arsg	ENSMUSG00000020604	0.922445041430936	0.922445041430936	0.0718551089340876	0.215565326802263	0.467009962776288	0.700514944164432
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Samd8	ENSMUSG00000021770	0.290984282074805	0.5155648232968	0.5155648232968	0.5155648232968	0.450794830295118	0.5155648232968
Arsa	ENSMUSG00000022620	0.347639524025037	0.454258017332816	0.177153312234059	0.454258017332816	0.454258017332816	0.454258017332816
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Asah2	ENSMUSG00000024887	0.711854160331342	0.711854160331342	0.578113371816017	0.711854160331342	0.514934023620344	0.711854160331342
Neu3	ENSMUSG00000035239	0.295581119060361	0.443371678590541	0.245326864841171	0.443371678590541	0.852940894477647	0.852940894477647
Ormdl3	ENSMUSG00000038150	0.0451153644990944	0.135346093497283	0.174692232033629	0.262038348050444	0.852832278580641	0.852832278580641
Spns2	ENSMUSG00000040447	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886967	0.505838378028518	0.514934023620345
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931
Neu2	ENSMUSG00000079434	0.392243127063687	0.588364690595531	0.190629863394776	0.571889590184328	0.92356607045265	0.92356607045265

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Metabolism of amino acids and derivatives

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlat	ENSMUSG00000000168	0.442211413534161	0.563799176258241	0.00793771651372562	0.0238131495411769	0.563799176258241	0.563799176258241
Ckmt1	ENSMUSG00000000308	0.711854160331342	0.711854160331342	0.29252580908486	0.711854160331342	0.711240436189781	0.711854160331342
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Dio2	ENSMUSG00000007682	0.292909738490495	0.439364607735743	0.0546809717320726	0.164042915196218	0.511420431658568	0.511420431658568
Slc3a2	ENSMUSG00000010095	0.148115998140416	0.375428758901986	0.250285839267991	0.375428758901986	0.778911768167544	0.778911768167544
Chdh	ENSMUSG00000015970	0.782117202022501	0.782117202022501	0.453225835454266	0.679838753181399	0.452880492349546	0.679838753181399
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Slc6a8	ENSMUSG00000019558	0.21549027811633	0.64647083434899	0.926658283600152	0.926658283600152	0.577829325134931	0.866743987702397
Ddc	ENSMUSG00000020182	0.0592616003460512	0.0888924005190768	0.00161470887631957	0.0048441266289587	0.852065168704833	0.852065168704833
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Arg2	ENSMUSG00000021125	0.853694531487825	1	0.0733738589968007	0.220121576990402	1	1
Ckmt2	ENSMUSG00000021622	0.381566259882379	0.710416009055326	0.710416009055326	0.710416009055326	0.625832387442502	0.710416009055326
Psmd6	ENSMUSG00000021737	0.78180291566155	0.92622377157404	0.779238691542963	0.92622377157404	0.92622377157404	0.92622377157404
Glud1	ENSMUSG00000021794	0.148115998140415	0.222173997210623	0.044737329683373	0.134211989050119	0.638824656785692	0.638824656785692
Gpt	ENSMUSG00000022546	0.343537039781257	0.515305559671886	0.329576740674783	0.515305559671886	0.569937449249116	0.569937449249116
Cbs	ENSMUSG00000024039	0.51270683838022	0.772874592839992	1	1	0.515249728559994	0.772874592839992
Gldc	ENSMUSG00000024827	0.211477675547591	0.317216513321387	0.179945789077372	0.317216513321387	0.778747761033626	0.778747761033626
Aldh18a1	ENSMUSG00000025007	0.337435786255283	0.506153679382925	0.0756145297453646	0.226843589236094	0.773122046545957	0.773122046545957
Psmd5	ENSMUSG00000026869	0.711240436189781	0.853801250889739	0.514300775319626	0.853801250889739	0.853801250889739	0.853801250889739
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Aldh4a1	ENSMUSG00000028737	0.455625354715449	0.766645874397711	0.853049270252403	0.853049270252403	0.511097249598474	0.766645874397711
Enoph1	ENSMUSG00000029326	0.456305241393103	0.684457862089655	0.453570536021945	0.684457862089655	1	1
Psph	ENSMUSG00000029446	0.570836132666921	0.706616781330066	0.706616781330066	0.706616781330066	0.345037391052887	0.706616781330066
Aass	ENSMUSG00000029695	0.166489709738751	0.166489709738751	0.0287722902807987	0.0863168708423962	0.0642056836831391	0.0963085255247086
Slc25a15	ENSMUSG00000031482	0.0325051220296005	0.0975153660888015	0.0958690133561599	0.14380352003424	0.514934023620345	0.514934023620345
Slc25a21	ENSMUSG00000035472	0.914410605267641	1	0.82682471578651	1	1	1
Psma8	ENSMUSG00000036743	0.14116671981935	0.211750079729025	0.281936405938515	0.281936405938515	0.0314025154922878	0.0942075464768635
Prodh2	ENSMUSG00000036892	0.559988304776178	0.559988304776178	0.431680053324131	0.559988304776178	0.490096264582703	0.559988304776178
Bbox1	ENSMUSG00000041660	0.321747661812897	0.321747661812897	0.0834655302699765	0.250396590809929	0.220723922642366	0.321747661812897
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Sephs2	ENSMUSG00000049091	0.0321889748775513	0.0482834623163269	0.0129100470219435	0.0387301410658306	0.694011247640131	0.694011247640131
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833
Amd1	ENSMUSG00000075232	0.781170242226513	0.781170242226513	0.451840588205062	0.781170242226513	0.711854160331342	0.781170242226513
Psme3	ENSMUSG00000078652	0.853372965654504	0.853480389728993	0.853480389728993	0.853480389728993	0.78180291566155	0.853480389728993

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Phospholipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Pla1a	ENSMUSG00000002847	0.119631084167591	0.323235417174495	0.21549027811633	0.323235417174495	0.578113371816017	0.578113371816017
Lpcat3	ENSMUSG00000004270	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739	0.853801250889739	0.853801250889739
Pcyt1a	ENSMUSG00000005615	0.399548817627028	1	0.7802108304765	1	1	1
Slc44a4	ENSMUSG00000007034	0.9255572759333	0.9255572759333	0.208897379073412	0.626692137220235	0.852504981253341	0.9255572759333
Tnfaip8l2	ENSMUSG00000013707	0.122484825003983	0.367454475011948	0.850151080737202	0.850151080737202	0.62976545519988	0.850151080737202
Mtmr4	ENSMUSG00000018401	0.254414773803597	0.639337105615665	0.454600801949285	0.639337105615665	0.639337105615665	0.639337105615665
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Chka	ENSMUSG00000024843	1	1	0.643853282854191	0.965779924281287	0.398829756175299	0.965779924281287
Pcyt2	ENSMUSG00000025137	0.852832278580641	0.852832278580641	0.514934023620345	0.852832278580641	0.711650020253571	0.852832278580641
Lpgat1	ENSMUSG00000026623	1	1	0.926003599371282	1	0.57113445032749	1
Fam73b	ENSMUSG00000026858	0.575824878403157	0.575824878403157	0.000333936947699979	0.00100181084309994	0.023669712774514	0.035504569161771
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Pip5k1a	ENSMUSG00000028126	0.399548817627028	0.865889271386954	0.577259514257969	0.865889271386954	1	1
Mfsd2a	ENSMUSG00000028655	1	1	0.923197812692242	1	0.643359829732651	1
Pi4k2b	ENSMUSG00000029186	0.293293089483362	0.852940894477647	0.852940894477647	0.852940894477647	0.779888212132595	0.852940894477647
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Gde1	ENSMUSG00000033917	0.776919261684345	0.849805525376199	0.000616356194285664	0.00184906858285699	0.849805525376199	0.849805525376199
Inpp5j	ENSMUSG00000034570	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344	0.853372965654504	0.926333123228344
Mboat1	ENSMUSG00000038732	0.640355507848752	0.710001140920767	0.637274134311157	0.710001140920767	0.710001140920767	0.710001140920767
Pla2g6	ENSMUSG00000042632	0.568427079091759	0.568427079091759	0.0315593554855452	0.0946780664566356	0.295581119060361	0.443371678590541
Tnfaip8l1	ENSMUSG00000044469	0.347639524025037	0.679320738524319	0.711650020253571	0.711650020253571	0.452880492349546	0.679320738524319
Liph	ENSMUSG00000044626	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.577829325134931	0.642864324224729
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Chpt1	ENSMUSG00000060002	1	1	0.0181899024051318	0.0545697072153953	0.85117361048289	1
Ddhd2	ENSMUSG00000061313	0.782117202022501	0.853694531487825	0.853694531487825	0.853694531487825	0.78180291566155	0.853694531487825
Etnk2	ENSMUSG00000070644	0.13512704279113	0.202690564186696	0.00153425095635554	0.00460275286906663	0.374003134453724	0.374003134453724

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Transport of inorganic cations/anions and amino acids/oligopeptides

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sri	ENSMUSG00000003161	0.11810342389482	0.255901190956604	0.255901190956604	0.255901190956604	0.255530331334266	0.255901190956604
Slc1a3	ENSMUSG00000005360	0.781960228679124	0.926387617028817	0.781960228679124	0.926387617028817	0.926387617028817	0.926387617028817
Slc3a2	ENSMUSG00000010095	0.148115998140416	0.375428758901986	0.250285839267991	0.375428758901986	0.778911768167544	0.778911768167544
Slc12a7	ENSMUSG00000017756	0.214037080764326	0.642111242292977	0.851732715229127	0.851732715229127	0.57113445032749	0.851732715229127
Slc25a22	ENSMUSG00000019082	0.642366752097095	0.643359829732651	0.34837756124189	0.643359829732651	0.643359829732651	0.643359829732651
Slc16a10	ENSMUSG00000019838	0.563485358844814	0.563485358844814	0.297095062262362	0.563485358844814	0.393724994268831	0.563485358844814
Slc5a8	ENSMUSG00000020062	0.762507504068942	0.762507504068942	0.00700808200338927	0.0210242460101678	0.246861959455465	0.370292939183197
Slc36a1	ENSMUSG00000020261	0.237525696869751	0.712577090609252	1	1	0.576973746230334	0.865460619345501
Slc7a8	ENSMUSG00000022180	0.573791743469336	0.780851835278818	0.21549027811633	0.64647083434899	0.780851835278818	0.780851835278818
Slc1a1	ENSMUSG00000024935	0.76875013537822	0.919906712313455	0.919906712313455	0.919906712313455	0.11810342389482	0.354310271684459
Slc15a1	ENSMUSG00000025557	0.711240436189781	0.926658283600152	0.643359829732651	0.926658283600152	0.926658283600152	0.926658283600152
Slc38a5	ENSMUSG00000031170	0.343537039781257	0.343537039781257	0.0741204440774081	0.222361332232224	0.249528554620971	0.343537039781257
Slc12a3	ENSMUSG00000031766	0.701310685803632	0.701310685803632	0.0706396252934259	0.105959437940139	0.0212382357534491	0.0637147072603474
Slc9a3	ENSMUSG00000036123	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504
Slc43a2	ENSMUSG00000038178	0.0441715176243984	0.132514552873195	0.398108175780842	0.597162263671263	1	1
Slc5a12	ENSMUSG00000041644	1	1	0.926658283600152	1	0.926658283600152	1
Slc24a4	ENSMUSG00000041771	0.505169133438821	0.637793186752488	0.227062445905894	0.637793186752488	0.637793186752488	0.637793186752488
Slc17a5	ENSMUSG00000049624	0.576973746230334	0.576973746230334	0.456305241393103	0.576973746230334	0.442211413534162	0.576973746230334
Slc4a5	ENSMUSG00000068323	0.690028363829288	0.690028363829288	0.379206615039809	0.568809922559714	0.224181550151583	0.568809922559714
Slc17a7	ENSMUSG00000070570	0.926604389137101	0.926604389137101	0.641616487517698	0.926604389137101	0.394829509482604	0.926604389137101

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Synthesis of PA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Agpat3	ENSMUSG00000001211	0.11595859961889	0.173937899428334	0.0360673631509441	0.108202089452832	1	1
Pld2	ENSMUSG00000020828	0.711650020253571	0.78180291566155	0.78180291566155	0.78180291566155	0.299349060054895	0.78180291566155
Gpd1	ENSMUSG00000023019	0.255901190956604	0.572349389823568	0.381566259882379	0.572349389823568	1	1
Agpat4	ENSMUSG00000023827	0.11595859961889	0.347875798856669	0.641867098978198	0.711034989117171	0.711034989117171	0.711034989117171
Fam73b	ENSMUSG00000026858	0.575824878403157	0.575824878403157	0.000333936947699979	0.00100181084309994	0.023669712774514	0.035504569161771
Lpcat4	ENSMUSG00000027134	0.295581119060361	0.443371678590541	0.0756145297453648	0.226843589236094	0.777255087907932	0.777255087907932
Agpat9	ENSMUSG00000029314	0.782117202022501	0.782117202022501	0.782117202022501	0.782117202022501	0.642864324224729	0.782117202022501
Agpat6	ENSMUSG00000031545	0.570836132666921	0.57113445032749	0.511097249598474	0.57113445032749	0.57113445032749	0.57113445032749
Liph	ENSMUSG00000044626	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.577829325134931	0.642864324224729
Gpd1l	ENSMUSG00000050627	0.0577292451600846	0.0996408635373811	0.0664272423582541	0.0996408635373811	0.384286524841344	0.384286524841344
Ddhd2	ENSMUSG00000061313	0.782117202022501	0.853694531487825	0.853694531487825	0.853694531487825	0.78180291566155	0.853694531487825

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Phase I - Functionalization of compounds

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
Cyb5r3	ENSMUSG00000018042	0.255901190956604	0.383851786434905	0.170434860179341	0.383851786434905	0.92589277149125	0.92589277149125
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Smox	ENSMUSG00000027333	0.711650020253571	0.711650020253571	0.297848640636702	0.711650020253571	0.643853282854191	0.711650020253571
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Maob	ENSMUSG00000040147	0.711240436189781	0.711240436189781	0.298599969973533	0.711240436189781	0.643359829732651	0.711240436189781
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Adh7	ENSMUSG00000055301	0.565668046214817	0.574957087247654	0.574957087247654	0.574957087247654	0.387353206758794	0.574957087247654
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Marc2	ENSMUSG00000073481	0.570836132666921	0.570836132666921	0.0497293992720784	0.149188197816235	0.570836132666921	0.570836132666921
Adh1	ENSMUSG00000074207	0.848280005680805	1	0.134113174211452	0.402339522634355	1	1
Cyp4v3	ENSMUSG00000079057	0.78148726569172	0.926550375688041	0.853801250889739	0.926550375688041	0.926550375688041	0.926550375688041

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Sphingolipid de novo biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Cers2	ENSMUSG00000015714	0.852832278580641	0.852832278580641	0.642864324224729	0.852832278580641	0.290984282074805	0.852832278580641
Sgpl1	ENSMUSG00000020097	0.442211413534161	0.926658283600152	0.926658283600152	0.926658283600152	0.92589277149125	0.926658283600152
Sptlc2	ENSMUSG00000021036	0.926658283600152	0.926658283600152	5.17062302895139e-05	0.000155118690868542	0.576973746230334	0.865460619345501
Sgpp1	ENSMUSG00000021054	0.926333123228344	0.926333123228344	0.388491809581663	0.865460619345501	0.576973746230334	0.865460619345501
Ppap2a	ENSMUSG00000021759	0.853694531487825	0.926550375688041	0.17750354896016	0.532510646880481	0.926550375688041	0.926550375688041
Samd8	ENSMUSG00000021770	0.290984282074805	0.5155648232968	0.5155648232968	0.5155648232968	0.450794830295118	0.5155648232968
Aldh3b1	ENSMUSG00000024885	0.78148726569172	0.78148726569172	0.451840588205062	0.78148726569172	0.576973746230334	0.78148726569172
Ormdl3	ENSMUSG00000038150	0.0451153644990944	0.135346093497283	0.174692232033629	0.262038348050444	0.852832278580641	0.852832278580641
Spns2	ENSMUSG00000040447	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886967	0.505838378028518	0.514934023620345
Sphk2	ENSMUSG00000057342	0.11810342389482	0.354310271684459	0.392985378348026	0.395196379647461	0.395196379647461	0.395196379647461
Sphk1	ENSMUSG00000061878	0.573498913947369	0.577829325134931	0.205174703261494	0.577829325134931	0.577829325134931	0.577829325134931

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Biosynthesis of DHA-derived SPMs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Hpgd	ENSMUSG00000031613	0.17750354896016	0.520348625898199	0.926550375688041	0.926550375688041	0.346899083932133	0.520348625898199
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504

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alpha-linolenic (omega3) and linoleic (omega6) acid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933

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alpha-linolenic acid (ALA) metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933

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Biosynthesis of specialized proresolving mediators (SPMs)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Lta4h	ENSMUSG00000015889	0.0763619660358785	0.229085898107636	0.513665062682276	0.770497594023414	0.7802108304765	0.7802108304765
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Hpgd	ENSMUSG00000031613	0.17750354896016	0.520348625898199	0.926550375688041	0.926550375688041	0.346899083932133	0.520348625898199
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504

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Cytochrome P450 - arranged by substrate type

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp51	ENSMUSG00000001467	0.0721303428592822	0.216391028577847	0.712057867818062	0.774871910813158	0.774871910813158	0.774871910813158
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Cyp27b1	ENSMUSG00000006724	0.0756145297453646	0.17990425710657	0.298224585822431	0.298224585822431	0.11993617140438	0.17990425710657
Cyp39a1	ENSMUSG00000023963	0.853801250889739	0.926441990075769	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2r1	ENSMUSG00000030670	0.456305241393103	0.772401035430517	0.514934023620344	0.772401035430517	1	1
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854
Cyp4v3	ENSMUSG00000079057	0.78148726569172	0.926550375688041	0.853801250889739	0.926550375688041	0.926550375688041	0.926550375688041

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Digestion and absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Guca2a	ENSMUSG00000023247	0.211110344399808	0.231130630776632	0.231130630776632	0.231130630776632	0.231130630776632	0.231130630776632
Lct	ENSMUSG00000026354	0.708745765211584	0.852832278580641	0.453570536021945	0.852832278580641	0.852832278580641	0.852832278580641
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Sis	ENSMUSG00000027790	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853694531487825	0.853694531487825
Slc2a5	ENSMUSG00000028976	0.346899083932133	0.573498913947369	0.454942951775342	0.573498913947369	0.573498913947369	0.573498913947369
Pir	ENSMUSG00000031379	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.346527959006435	0.711854160331342
Mgam	ENSMUSG00000068587	0.255530331334266	0.348008842235184	0.120850531362929	0.348008842235184	0.348008842235184	0.348008842235184
Ddi2	ENSMUSG00000078515	0.853372965654504	0.853372965654504	0.297848640636702	0.513607944031322	0.342405296020881	0.513607944031322

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Plasma lipoprotein assembly, remodeling, and clearance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Soat2	ENSMUSG00000023045	0.216214347033995	0.648643041101984	1	1	0.710208797518812	1
Lipa	ENSMUSG00000024781	0.633039971999413	0.923443907074248	0.162867964743396	0.488603894230187	0.923443907074248	0.923443907074248
P4hb	ENSMUSG00000025130	0.7802108304765	0.7802108304765	0.329176790045262	0.7802108304765	0.709375484777034	0.7802108304765
Nceh1	ENSMUSG00000027698	0.148772260628989	0.148772260628989	0.00253244992826164	0.00759734978478493	0.0488765001588118	0.0733147502382177
Mttp	ENSMUSG00000028158	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.7802108304765	0.781170242226513
Apoa5	ENSMUSG00000032079	0.708323672944427	0.708323672944427	0.0168921052924601	0.0506763158773803	0.513026869856283	0.708323672944427
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092
Pcsk9	ENSMUSG00000044254	0.926003599371281	0.926333123228344	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344
Ap2a1	ENSMUSG00000060279	0.395196379647461	0.566593564630738	0.566593564630738	0.566593564630738	0.12935516793705	0.388065503811151
Nr1h2	ENSMUSG00000060601	0.215127611919161	0.322691417878742	1	1	0.202543053799149	0.322691417878742

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Phase II - Conjugation of compounds

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Comt	ENSMUSG00000000326	1	1	0.21549027811633	0.64647083434899	0.640355507848752	0.960533261773128
Gstt1	ENSMUSG00000001663	0.708534948098331	0.708534948098331	0.041737700208629	0.125213100625887	0.443669460449296	0.665504190673944
Gstm7	ENSMUSG00000004035	0.766080166042519	0.846460676830692	0.072378961026407	0.217136883079221	0.846460676830692	0.846460676830692
Ggt1	ENSMUSG00000006345	0.119936171404379	0.179904257106569	0.0886202385494147	0.179904257106569	0.638310022345193	0.638310022345193
Oplah	ENSMUSG00000022562	0.45596561163947	0.683948417459205	0.215127611919161	0.645382835757484	0.853694531487825	0.853694531487825
Bpnt1	ENSMUSG00000026617	0.293293089483362	0.439939634225043	1	1	0.261555237955603	0.439939634225043
Gstm4	ENSMUSG00000027890	0.443669460449296	0.665504190673945	0.0129100470219435	0.0387301410658306	0.701310685803632	0.701310685803632
Slc35d1	ENSMUSG00000028521	0.45596561163947	0.45596561163947	0.297848640636702	0.45596561163947	0.345037391052887	0.45596561163947
Sult1b1	ENSMUSG00000029269	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155	0.5155648232968	0.78180291566155
Acsm5	ENSMUSG00000030972	0.212942741031873	0.63882822309562	0.852723421673413	0.924930181917758	0.924930181917758	0.924930181917758
Ugt2a3	ENSMUSG00000035780	0.299349060054895	0.682414427663012	0.454942951775342	0.682414427663012	0.926003599371282	0.926003599371282
Mat2a	ENSMUSG00000053907	0.452880492349546	0.679320738524319	0.0908536824179312	0.272561047253794	0.9255572759333	0.9255572759333
Gstm1	ENSMUSG00000058135	0.6978446011211	0.6978446011211	0.0303111090728679	0.0909333272186037	0.444394285043028	0.666591427564543
Impad1	ENSMUSG00000066324	0.17610058307789	0.264150874616835	0.138156294413154	0.264150874616835	0.635703516568382	0.635703516568382
Gstm6	ENSMUSG00000068762	0.287873078401389	0.431809617602084	0.283134662157423	0.431809617602084	0.851061028660105	0.851061028660105
Ugt1a1	ENSMUSG00000089960	0.115037265385284	0.345111796155853	0.384672302267076	0.384672302267076	0.333146020247509	0.384672302267076
Ugt1a7c	ENSMUSG00000090124	0.246478961478169	0.641867098978197	0.514934023620345	0.641867098978197	0.641867098978197	0.641867098978197

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Chylomicron assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
P4hb	ENSMUSG00000025130	0.7802108304765	0.7802108304765	0.329176790045262	0.7802108304765	0.709375484777034	0.7802108304765
Mttp	ENSMUSG00000028158	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.7802108304765	0.781170242226513
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092

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Inositol transporters

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc5a11	ENSMUSG00000030769	0.146800541856249	0.260448650831748	0.173632433887832	0.260448650831748	0.708745765211584	0.708745765211584
Slc2a13	ENSMUSG00000036298	0.78148726569172	0.78180291566155	0.511742979522636	0.78180291566155	0.78180291566155	0.78180291566155
Slc5a3	ENSMUSG00000089774	0.177153312234059	0.531459936702176	0.642366752097095	0.853694531487825	0.853694531487825	0.853694531487825

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Miscellaneous substrates

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp4f14	ENSMUSG00000024292	0.78180291566155	0.926658283600152	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152
Cyp4b1	ENSMUSG00000028713	0.643359829732651	0.853801250889739	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Cyp4a14	ENSMUSG00000028715	0.00338354024244379	0.00507531036366569	0.135801817691504	0.135801817691504	0.00309588067649959	0.00507531036366569
Cyp3a25	ENSMUSG00000029630	0.640355507848752	0.853372965654504	0.853372965654504	0.853372965654504	0.514934023620345	0.853372965654504
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp3a11	ENSMUSG00000056035	0.453225835454266	0.764697207151727	0.78180291566155	0.78180291566155	0.509798138101151	0.764697207151727
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504
Cyp4a10	ENSMUSG00000066072	0.660039584419012	0.660039584419012	0.337653038060633	0.620512422115854	0.413674948077236	0.620512422115854

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Degradation of cysteine and homocysteine

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833

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Beta-oxidation of very long chain fatty acids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Acot6	ENSMUSG00000043487	0.851732715229127	0.851732715229127	0.214037080764326	0.642111242292977	0.577259514257969	0.851732715229127

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Protein localization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pex19	ENSMUSG00000003464	0.148115998140415	0.222173997210623	0.0958690133561599	0.222173997210623	0.513665062682276	0.513665062682276
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Aldh3a2	ENSMUSG00000010025	0.708323672944427	0.711034989117171	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Dhrs4	ENSMUSG00000022210	0.636229315311352	0.636229315311352	0.0219958379984644	0.0659875139953933	0.636229315311352	0.636229315311352
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Slc25a17	ENSMUSG00000022404	1	1	0.926441990075769	1	0.643853282854191	1
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636
Abcd3	ENSMUSG00000028127	0.853907737111068	0.853907737111068	0.177153312234059	0.531459936702178	0.853907737111068	0.853907737111068
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092

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Biosynthesis of maresins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cyp2c29	ENSMUSG00000003053	0.597165960255876	0.756609537973847	0.0950082814880288	0.285024844464086	0.756609537973847	0.756609537973847
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Cyp3a13	ENSMUSG00000029727	0.852940894477647	0.852940894477647	0.290210015182478	0.770497594023414	0.513665062682276	0.770497594023414
Cyp2d22	ENSMUSG00000061740	0.852940894477647	0.853372965654504	0.452880492349546	0.853372965654504	0.853372965654504	0.853372965654504

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LDL clearance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Soat2	ENSMUSG00000023045	0.216214347033995	0.648643041101984	1	1	0.710208797518812	1
Lipa	ENSMUSG00000024781	0.633039971999413	0.923443907074248	0.162867964743396	0.488603894230187	0.923443907074248	0.923443907074248
Nceh1	ENSMUSG00000027698	0.148772260628989	0.148772260628989	0.00253244992826164	0.00759734978478493	0.0488765001588118	0.0733147502382177
Pcsk9	ENSMUSG00000044254	0.926003599371281	0.926333123228344	0.926333123228344	0.926333123228344	0.853480389728993	0.926333123228344
Ap2a1	ENSMUSG00000060279	0.395196379647461	0.566593564630738	0.566593564630738	0.566593564630738	0.12935516793705	0.388065503811151

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Sulfur amino acid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sqrdl	ENSMUSG00000005803	0.256271555563966	0.34837756124189	0.0958690133561599	0.28760704006848	0.34837756124189	0.34837756124189
Cbs	ENSMUSG00000024039	0.51270683838022	0.772874592839992	1	1	0.515249728559994	0.772874592839992
Cth	ENSMUSG00000028179	0.216214347033995	0.324321520550992	0.206668954082486	0.324321520550992	0.702439833942814	0.702439833942814
Enoph1	ENSMUSG00000029326	0.456305241393103	0.684457862089655	0.453570536021945	0.684457862089655	1	1
Tst	ENSMUSG00000044986	0.710001140920767	0.710001140920767	0.514934023620345	0.710001140920767	0.513665062682276	0.710001140920767
Suox	ENSMUSG00000049858	0.635703516568382	0.953555274852574	0.398108175780842	0.953555274852574	1	1
Ethe1	ENSMUSG00000064254	0.096425230538547	0.289275691615641	0.255530331334266	0.383295497001399	0.852065168704833	0.852065168704833

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Lysine catabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dlst	ENSMUSG00000004789	1	1	0.0919695072173338	0.275908521652001	0.640861491578951	0.961292237368426
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Ogdh	ENSMUSG00000020456	0.17924968721805	0.537749061654149	0.452880492349546	0.679320738524319	0.852940894477647	0.852940894477647
Aass	ENSMUSG00000029695	0.166489709738751	0.166489709738751	0.0287722902807987	0.0863168708423962	0.0642056836831391	0.0963085255247086
Slc25a21	ENSMUSG00000035472	0.914410605267641	1	0.82682471578651	1	1	1

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Nuclear Receptor transcription pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nr1i3	ENSMUSG00000005677	0.637274134311157	0.706616781330066	0.576973746230334	0.706616781330066	0.706616781330066	0.706616781330066
Nr1d1	ENSMUSG00000020889	0.395928178642446	0.593892267963669	0.643359829732651	0.643359829732651	0.179945789077372	0.539837367232115
Esrrb	ENSMUSG00000021255	0.212211059210313	0.31831658881547	0.116572120727418	0.31831658881547	0.850608132982798	0.850608132982798
Nr1i2	ENSMUSG00000022809	0.252920381501206	0.704220158648919	0.704220158648919	0.704220158648919	0.636229315311352	0.704220158648919
Esrrg	ENSMUSG00000026610	0.640608766263372	0.71082910328023	0.71082910328023	0.71082910328023	0.570836132666921	0.71082910328023
Pgr	ENSMUSG00000031870	0.0684072100296622	0.102610815044493	0.214037080764326	0.214037080764326	0.0235394205027691	0.0706182615083072
Nr0b2	ENSMUSG00000037583	0.777755996383525	0.851061028660105	0.851061028660105	0.851061028660105	0.144489143676808	0.433467431030423
Nr1h4	ENSMUSG00000047638	0.5155648232968	0.7733472349452	0.044926265292481	0.134778795877443	0.92589277149125	0.92589277149125
Thra	ENSMUSG00000058756	0.119631084167592	0.179446626251387	0.00755778364492931	0.0226733509347879	0.57113445032749	0.57113445032749
Nr1h2	ENSMUSG00000060601	0.215127611919161	0.322691417878742	1	1	0.202543053799149	0.322691417878742

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Organic anion transporters

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc25a22	ENSMUSG00000019082	0.642366752097095	0.643359829732651	0.34837756124189	0.643359829732651	0.643359829732651	0.643359829732651
Slc5a8	ENSMUSG00000020062	0.762507504068942	0.762507504068942	0.00700808200338927	0.0210242460101678	0.246861959455465	0.370292939183197
Slc17a5	ENSMUSG00000049624	0.576973746230334	0.576973746230334	0.456305241393103	0.576973746230334	0.442211413534162	0.576973746230334
Slc17a7	ENSMUSG00000070570	0.926604389137101	0.926604389137101	0.641616487517698	0.926604389137101	0.394829509482604	0.926604389137101

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Plasma lipoprotein assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoc2	ENSMUSG00000002992	0.642366752097095	0.926003599371281	0.399548817627028	0.926003599371281	0.926003599371281	0.926003599371281
Abca1	ENSMUSG00000015243	0.299349060054895	0.600398061312773	0.643359829732651	0.643359829732651	0.400265374208515	0.600398061312773
Apob	ENSMUSG00000020609	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
P4hb	ENSMUSG00000025130	0.7802108304765	0.7802108304765	0.329176790045262	0.7802108304765	0.709375484777034	0.7802108304765
Mttp	ENSMUSG00000028158	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.7802108304765	0.781170242226513
Apoa4	ENSMUSG00000032080	0.577829325134931	0.866743987702397	0.57466664340579	0.866743987702397	0.925669613555092	0.925669613555092

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Intestinal hexose absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Slc2a5	ENSMUSG00000028976	0.346899083932133	0.573498913947369	0.454942951775342	0.573498913947369	0.573498913947369	0.573498913947369
Ddi2	ENSMUSG00000078515	0.853372965654504	0.853372965654504	0.297848640636702	0.513607944031322	0.342405296020881	0.513607944031322

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Peroxisomal protein import

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Pipox	ENSMUSG00000017453	0.348377561241889	0.772401035430517	0.926550375688041	0.926550375688041	0.514934023620344	0.772401035430517
Acox1	ENSMUSG00000020777	0.853372965654504	0.853372965654504	0.780851835278817	0.853372965654504	0.852832278580641	0.853372965654504
Acot3	ENSMUSG00000021228	0.630592275825428	0.630592275825428	0.37481190387997	0.630592275825428	0.628375028474863	0.630592275825428
Ephx2	ENSMUSG00000022040	0.702439833942814	0.7802108304765	0.334323804341914	0.7802108304765	0.7802108304765	0.7802108304765
Dhrs4	ENSMUSG00000022210	0.636229315311352	0.636229315311352	0.0219958379984644	0.0659875139953933	0.636229315311352	0.636229315311352
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Ehhadh	ENSMUSG00000022853	0.575824878403157	0.575824878403157	0.344663224299303	0.516994836448954	0.24106236027001	0.516994836448954
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Phyh	ENSMUSG00000026664	0.924987846321933	0.924987846321933	0.0129100470219435	0.0387301410658306	0.454942951775342	0.682414427663012
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202
Cat	ENSMUSG00000027187	0.450444934184774	0.511742979522636	0.134789313526392	0.404367940579177	0.511742979522636	0.511742979522636

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Intestinal absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc2a2	ENSMUSG00000027690	0.853372965654504	0.853372965654504	0.454600801949285	0.853372965654504	0.852940894477647	0.853372965654504
Slc2a5	ENSMUSG00000028976	0.346899083932133	0.573498913947369	0.454942951775342	0.573498913947369	0.573498913947369	0.573498913947369
Ddi2	ENSMUSG00000078515	0.853372965654504	0.853372965654504	0.297848640636702	0.513607944031322	0.342405296020881	0.513607944031322

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Beta-oxidation of pristanoyl-CoA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Crot	ENSMUSG00000003623	0.453570536021945	0.965779924281287	1	1	0.643853282854191	0.965779924281287
Amacr	ENSMUSG00000022244	0.0947558980989551	0.142133847148433	0.0140567816599278	0.0421703449797833	0.367839240677855	0.367839240677855
Hsd17b4	ENSMUSG00000024507	1	1	0.18064054691103	0.541921640733091	0.642864324224729	0.964296486337094
Crat	ENSMUSG00000026853	0.850151080737202	0.850151080737202	0.0644521829047254	0.193356548714176	0.775217051297351	0.850151080737202

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Linoleic acid (LA) metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Elovl1	ENSMUSG00000006390	0.509798138101151	0.576973746230334	0.395928178642446	0.576973746230334	0.576973746230334	0.576973746230334
Acsl1	ENSMUSG00000018796	0.926333123228344	0.926333123228344	0.00974037464901008	0.0292211239470303	0.781170242226513	0.926333123228344
Abcd1	ENSMUSG00000031378	0.254787123615605	0.764361370846815	0.925669613555092	0.925669613555092	0.705968934865368	0.925669613555092
Elovl5	ENSMUSG00000032349	0.779888212132595	0.924987846321933	0.710416009055326	0.924987846321933	0.924987846321933	0.924987846321933

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antiquewhite

Sulfur relay system

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mocs2	ENSMUSG00000015536	0.120850531362929	0.362551594088788	0.338976281569376	0.447621891168214	0.447621891168214	0.447621891168214
Mpst	ENSMUSG00000071711	0.398108175780842	0.514300775319626	0.514300775319626	0.514300775319626	0.454600801949285	0.514300775319626

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antiquewhite1

Spliceosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrnp27	ENSMUSG00000001158	0.575536202757516	0.575536202757516	0.298599969973533	0.450143880930327	0.300095920620218	0.450143880930327
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Snrpb2	ENSMUSG00000008333	0.92380865295296	0.92380865295296	0.511742979522636	0.92380865295296	0.637274134311157	0.92380865295296
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Sf3a3	ENSMUSG00000028902	0.453225835454266	0.453225835454266	0.214037080764326	0.453225835454266	0.450444934184774	0.453225835454266
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Lsm6	ENSMUSG00000031683	0.78180291566155	0.78180291566155	0.711650020253571	0.78180291566155	0.578396848531894	0.78180291566155
Lsm3	ENSMUSG00000034192	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739	0.78180291566155	0.853801250889739
Rbmxl1	ENSMUSG00000037070	0.643359829732651	0.926441990075769	0.058823267388015	0.176469802164045	0.926441990075769	0.926441990075769
Ppih	ENSMUSG00000060288	0.578113371816017	0.965779924281287	0.643853282854191	0.965779924281287	1	1
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172

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RNA transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Eif5b	ENSMUSG00000026083	0.639337105615664	0.639337105615664	0.298599969973533	0.597162263671263	0.398108175780842	0.597162263671263
Nmd3	ENSMUSG00000027787	0.78180291566155	0.926550375688041	0.148772260628989	0.446316781886968	0.926550375688041	0.926550375688041
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Snupn	ENSMUSG00000055334	0.45596561163947	0.45596561163947	0.120545895661627	0.361637686984882	0.45596561163947	0.45596561163947

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Proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Spinocerebellar ataxia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Wipi2	ENSMUSG00000029578	0.7802108304765	0.7802108304765	0.577259514257969	0.7802108304765	0.641867098978198	0.7802108304765
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Atg14	ENSMUSG00000037526	0.92589277149125	0.92589277149125	0.5155648232968	0.92589277149125	0.642864324224729	0.92589277149125
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Tbpl1	ENSMUSG00000071359	0.513026869856283	0.513026869856283	0.0969812105731562	0.290943631719469	0.216214347033995	0.324321520550992

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Ribosome biogenesis in eukaryotes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nhp2	ENSMUSG00000001056	0.578113371816017	0.578113371816017	0.148115998140416	0.444347994421247	0.454600801949285	0.578113371816017
Gtpbp4	ENSMUSG00000021149	0.782117202022501	0.782117202022501	0.0964252305385472	0.289275691615642	0.399548817627028	0.599323226440542
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Nmd3	ENSMUSG00000027787	0.78180291566155	0.926550375688041	0.148772260628989	0.446316781886968	0.926550375688041	0.926550375688041
Mphosph10	ENSMUSG00000030521	0.300095920620218	0.450143880930327	0.0741204440774083	0.222361332232225	0.853801250889739	0.853801250889739
Utp6	ENSMUSG00000035575	0.140165358447409	0.210248037671113	0.0236697127745139	0.0710091383235417	0.578113371816017	0.578113371816017
Wdr43	ENSMUSG00000041057	0.853694531487825	0.853694531487825	0.0441715176243983	0.132514552873195	0.399548817627028	0.599323226440542

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Protein processing in endoplasmic reticulum

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hsp90b1	ENSMUSG00000020048	0.148772260628989	0.223158390943484	0.146141353215796	0.223158390943484	0.640861491578951	0.640861491578951
Pdia6	ENSMUSG00000020571	0.399548817627028	0.767614469283954	0.511742979522636	0.767614469283954	1	1
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Hspa5	ENSMUSG00000026864	0.179945789077372	0.539837367232116	0.45149265530335	0.677238982955025	1	1
Rrbp1	ENSMUSG00000027422	0.779888212132595	0.779888212132595	0.11993617140438	0.359808514213139	0.400265374208515	0.600398061312773
Nsfl1c	ENSMUSG00000027455	0.148115998140415	0.222173997210623	0.0334587898203824	0.100376369461147	0.578113371816017	0.578113371816017
Plaa	ENSMUSG00000028577	0.777922216623952	0.777922216623952	0.0964252305385472	0.289275691615642	0.400265374208515	0.600398061312773
March6	ENSMUSG00000039100	0.147458757705094	0.223158390943484	0.148772260628989	0.223158390943484	0.853694531487825	0.853694531487825
Ssr2	ENSMUSG00000041355	0.710416009055326	0.92622377157404	0.452880492349546	0.92622377157404	0.92622377157404	0.92622377157404
Vimp	ENSMUSG00000075701	0.297848640636702	0.782117202022501	0.782117202022501	0.782117202022501	0.578396848531894	0.782117202022501

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Metabolism of RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrnp27	ENSMUSG00000001158	0.575536202757516	0.575536202757516	0.298599969973533	0.450143880930327	0.300095920620218	0.450143880930327
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Hnrnpa2b1	ENSMUSG00000004980	0.256271555563966	0.5155648232968	0.5155648232968	0.5155648232968	0.514300775319626	0.5155648232968
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Snrpb2	ENSMUSG00000008333	0.92380865295296	0.92380865295296	0.511742979522636	0.92380865295296	0.637274134311157	0.92380865295296
Nol11	ENSMUSG00000018433	1	1	0.514934023620344	0.772401035430517	0.0315593554855452	0.0946780664566356
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Ltv1	ENSMUSG00000019814	0.398108175780842	0.398108175780842	0.146800541856249	0.378818296296721	0.252545530864481	0.378818296296721
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Pes1	ENSMUSG00000020430	0.643359829732651	0.78180291566155	0.0231500557096833	0.06945016712905	0.78180291566155	0.78180291566155
Ftsj3	ENSMUSG00000020706	0.643359829732651	0.643359829732651	0.120850531362929	0.323235417174495	0.21549027811633	0.323235417174495
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Cwc27	ENSMUSG00000021715	0.254414773803597	0.255901190956604	0.0166824765447319	0.0500474296341957	0.255901190956604	0.255901190956604
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Ncl	ENSMUSG00000026234	1	1	0.213307944885796	0.639923834657388	0.642366752097095	0.963550128145642
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Ebna1bp2	ENSMUSG00000028729	0.576973746230334	0.853480389728993	0.0426702157436794	0.128010647231038	0.853480389728993	0.853480389728993
Sf3a3	ENSMUSG00000028902	0.453225835454266	0.453225835454266	0.214037080764326	0.453225835454266	0.450444934184774	0.453225835454266
Utp11l	ENSMUSG00000028907	0.252545530864481	0.378818296296722	0.21549027811633	0.378818296296722	0.926550375688041	0.926550375688041
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Mphosph10	ENSMUSG00000030521	0.300095920620218	0.450143880930327	0.0741204440774083	0.222361332232225	0.853801250889739	0.853801250889739
Lsm6	ENSMUSG00000031683	0.78180291566155	0.78180291566155	0.711650020253571	0.78180291566155	0.578396848531894	0.78180291566155
Mphosph6	ENSMUSG00000031843	0.393724994268831	0.456305241393103	0.0964252305385472	0.289275691615642	0.456305241393103	0.456305241393103
Anp32a	ENSMUSG00000032249	0.852940894477647	0.852940894477647	0.852832278580641	0.852940894477647	0.454600801949285	0.852940894477647
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Lsm3	ENSMUSG00000034192	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739	0.78180291566155	0.853801250889739
Exosc1	ENSMUSG00000034321	0.853372965654504	0.853372965654504	0.0741204440774082	0.222361332232225	0.853372965654504	0.853372965654504
Utp6	ENSMUSG00000035575	0.140165358447409	0.210248037671113	0.0236697127745139	0.0710091383235417	0.578113371816017	0.578113371816017
Rbmxl1	ENSMUSG00000037070	0.643359829732651	0.926441990075769	0.058823267388015	0.176469802164045	0.926441990075769	0.926441990075769
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Wdr43	ENSMUSG00000041057	0.853694531487825	0.853694531487825	0.0441715176243983	0.132514552873195	0.399548817627028	0.599323226440542
Snupn	ENSMUSG00000055334	0.45596561163947	0.45596561163947	0.120545895661627	0.361637686984882	0.45596561163947	0.45596561163947
Txnl4a	ENSMUSG00000057130	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Ppih	ENSMUSG00000060288	0.578113371816017	0.965779924281287	0.643853282854191	0.965779924281287	1	1
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172
Gspt1	ENSMUSG00000062203	0.78180291566155	0.853372965654504	0.853372965654504	0.853372965654504	0.78148726569172	0.853372965654504
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995
Krr1	ENSMUSG00000063334	0.853907737111068	0.853907737111068	0.148772260628989	0.223158390943484	0.120850531362929	0.223158390943484
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Utp3	ENSMUSG00000070697	0.254414773803597	0.381622160705395	0.216214347033995	0.381622160705395	0.45596561163947	0.45596561163947
Sarnp	ENSMUSG00000078427	0.256271555563966	0.514934023620345	0.514934023620345	0.514934023620345	0.452880492349546	0.514934023620345

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rRNA processing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nol11	ENSMUSG00000018433	1	1	0.514934023620344	0.772401035430517	0.0315593554855452	0.0946780664566356
Ltv1	ENSMUSG00000019814	0.398108175780842	0.398108175780842	0.146800541856249	0.378818296296721	0.252545530864481	0.378818296296721
Pes1	ENSMUSG00000020430	0.643359829732651	0.78180291566155	0.0231500557096833	0.06945016712905	0.78180291566155	0.78180291566155
Ftsj3	ENSMUSG00000020706	0.643359829732651	0.643359829732651	0.120850531362929	0.323235417174495	0.21549027811633	0.323235417174495
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Ncl	ENSMUSG00000026234	1	1	0.213307944885796	0.639923834657388	0.642366752097095	0.963550128145642
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Ebna1bp2	ENSMUSG00000028729	0.576973746230334	0.853480389728993	0.0426702157436794	0.128010647231038	0.853480389728993	0.853480389728993
Utp11l	ENSMUSG00000028907	0.252545530864481	0.378818296296722	0.21549027811633	0.378818296296722	0.926550375688041	0.926550375688041
Mphosph10	ENSMUSG00000030521	0.300095920620218	0.450143880930327	0.0741204440774083	0.222361332232225	0.853801250889739	0.853801250889739
Mphosph6	ENSMUSG00000031843	0.393724994268831	0.456305241393103	0.0964252305385472	0.289275691615642	0.456305241393103	0.456305241393103
Exosc1	ENSMUSG00000034321	0.853372965654504	0.853372965654504	0.0741204440774082	0.222361332232225	0.853372965654504	0.853372965654504
Utp6	ENSMUSG00000035575	0.140165358447409	0.210248037671113	0.0236697127745139	0.0710091383235417	0.578113371816017	0.578113371816017
Wdr43	ENSMUSG00000041057	0.853694531487825	0.853694531487825	0.0441715176243983	0.132514552873195	0.399548817627028	0.599323226440542
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995
Krr1	ENSMUSG00000063334	0.853907737111068	0.853907737111068	0.148772260628989	0.223158390943484	0.120850531362929	0.223158390943484
Utp3	ENSMUSG00000070697	0.254414773803597	0.381622160705395	0.216214347033995	0.381622160705395	0.45596561163947	0.45596561163947

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Major pathway of rRNA processing in the nucleolus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nol11	ENSMUSG00000018433	1	1	0.514934023620344	0.772401035430517	0.0315593554855452	0.0946780664566356
Ltv1	ENSMUSG00000019814	0.398108175780842	0.398108175780842	0.146800541856249	0.378818296296721	0.252545530864481	0.378818296296721
Pes1	ENSMUSG00000020430	0.643359829732651	0.78180291566155	0.0231500557096833	0.06945016712905	0.78180291566155	0.78180291566155
Ftsj3	ENSMUSG00000020706	0.643359829732651	0.643359829732651	0.120850531362929	0.323235417174495	0.21549027811633	0.323235417174495
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Ncl	ENSMUSG00000026234	1	1	0.213307944885796	0.639923834657388	0.642366752097095	0.963550128145642
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Ebna1bp2	ENSMUSG00000028729	0.576973746230334	0.853480389728993	0.0426702157436794	0.128010647231038	0.853480389728993	0.853480389728993
Utp11l	ENSMUSG00000028907	0.252545530864481	0.378818296296722	0.21549027811633	0.378818296296722	0.926550375688041	0.926550375688041
Mphosph10	ENSMUSG00000030521	0.300095920620218	0.450143880930327	0.0741204440774083	0.222361332232225	0.853801250889739	0.853801250889739
Mphosph6	ENSMUSG00000031843	0.393724994268831	0.456305241393103	0.0964252305385472	0.289275691615642	0.456305241393103	0.456305241393103
Exosc1	ENSMUSG00000034321	0.853372965654504	0.853372965654504	0.0741204440774082	0.222361332232225	0.853372965654504	0.853372965654504
Utp6	ENSMUSG00000035575	0.140165358447409	0.210248037671113	0.0236697127745139	0.0710091383235417	0.578113371816017	0.578113371816017
Wdr43	ENSMUSG00000041057	0.853694531487825	0.853694531487825	0.0441715176243983	0.132514552873195	0.399548817627028	0.599323226440542
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995
Krr1	ENSMUSG00000063334	0.853907737111068	0.853907737111068	0.148772260628989	0.223158390943484	0.120850531362929	0.223158390943484
Utp3	ENSMUSG00000070697	0.254414773803597	0.381622160705395	0.216214347033995	0.381622160705395	0.45596561163947	0.45596561163947

Download data as csv

rRNA processing in the nucleus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nol11	ENSMUSG00000018433	1	1	0.514934023620344	0.772401035430517	0.0315593554855452	0.0946780664566356
Ltv1	ENSMUSG00000019814	0.398108175780842	0.398108175780842	0.146800541856249	0.378818296296721	0.252545530864481	0.378818296296721
Pes1	ENSMUSG00000020430	0.643359829732651	0.78180291566155	0.0231500557096833	0.06945016712905	0.78180291566155	0.78180291566155
Ftsj3	ENSMUSG00000020706	0.643359829732651	0.643359829732651	0.120850531362929	0.323235417174495	0.21549027811633	0.323235417174495
Rpp30	ENSMUSG00000024800	0.711854160331342	0.780851835278818	0.392243127063687	0.780851835278818	0.780851835278818	0.780851835278818
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Ncl	ENSMUSG00000026234	1	1	0.213307944885796	0.639923834657388	0.642366752097095	0.963550128145642
Nop56	ENSMUSG00000027405	0.514934023620345	0.514934023620345	0.0763619660358786	0.229085898107636	0.454600801949285	0.514934023620345
Ebna1bp2	ENSMUSG00000028729	0.576973746230334	0.853480389728993	0.0426702157436794	0.128010647231038	0.853480389728993	0.853480389728993
Utp11l	ENSMUSG00000028907	0.252545530864481	0.378818296296722	0.21549027811633	0.378818296296722	0.926550375688041	0.926550375688041
Mphosph10	ENSMUSG00000030521	0.300095920620218	0.450143880930327	0.0741204440774083	0.222361332232225	0.853801250889739	0.853801250889739
Mphosph6	ENSMUSG00000031843	0.393724994268831	0.456305241393103	0.0964252305385472	0.289275691615642	0.456305241393103	0.456305241393103
Exosc1	ENSMUSG00000034321	0.853372965654504	0.853372965654504	0.0741204440774082	0.222361332232225	0.853372965654504	0.853372965654504
Utp6	ENSMUSG00000035575	0.140165358447409	0.210248037671113	0.0236697127745139	0.0710091383235417	0.578113371816017	0.578113371816017
Wdr43	ENSMUSG00000041057	0.853694531487825	0.853694531487825	0.0441715176243983	0.132514552873195	0.399548817627028	0.599323226440542
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995
Krr1	ENSMUSG00000063334	0.853907737111068	0.853907737111068	0.148772260628989	0.223158390943484	0.120850531362929	0.223158390943484
Utp3	ENSMUSG00000070697	0.254414773803597	0.381622160705395	0.216214347033995	0.381622160705395	0.45596561163947	0.45596561163947

Download data as csv

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrnp27	ENSMUSG00000001158	0.575536202757516	0.575536202757516	0.298599969973533	0.450143880930327	0.300095920620218	0.450143880930327
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Hnrnpa2b1	ENSMUSG00000004980	0.256271555563966	0.5155648232968	0.5155648232968	0.5155648232968	0.514300775319626	0.5155648232968
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Snrpb2	ENSMUSG00000008333	0.92380865295296	0.92380865295296	0.511742979522636	0.92380865295296	0.637274134311157	0.92380865295296
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Cwc27	ENSMUSG00000021715	0.254414773803597	0.255901190956604	0.0166824765447319	0.0500474296341957	0.255901190956604	0.255901190956604
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Sf3a3	ENSMUSG00000028902	0.453225835454266	0.453225835454266	0.214037080764326	0.453225835454266	0.450444934184774	0.453225835454266
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Lsm6	ENSMUSG00000031683	0.78180291566155	0.78180291566155	0.711650020253571	0.78180291566155	0.578396848531894	0.78180291566155
Lsm3	ENSMUSG00000034192	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739	0.78180291566155	0.853801250889739
Rbmxl1	ENSMUSG00000037070	0.643359829732651	0.926441990075769	0.058823267388015	0.176469802164045	0.926441990075769	0.926441990075769
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Txnl4a	ENSMUSG00000057130	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Ppih	ENSMUSG00000060288	0.578113371816017	0.965779924281287	0.643853282854191	0.965779924281287	1	1
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172
Sarnp	ENSMUSG00000078427	0.256271555563966	0.514934023620345	0.514934023620345	0.514934023620345	0.452880492349546	0.514934023620345

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Translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl32	ENSMUSG00000015672	0.255530331334266	0.383295497001398	0.252545530864481	0.383295497001398	0.514300775319626	0.514300775319626
Mrpl22	ENSMUSG00000020514	0.509798138101151	0.764697207151727	0.776919261684345	0.776919261684345	0.452880492349546	0.764697207151727
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Eif5b	ENSMUSG00000026083	0.639337105615664	0.639337105615664	0.298599969973533	0.597162263671263	0.398108175780842	0.597162263671263
Mrrf	ENSMUSG00000026887	0.852940894477647	0.852940894477647	0.211110344399808	0.633331033199424	0.780851835278818	0.852940894477647
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375
Mrpl46	ENSMUSG00000030612	1	1	0.297848640636702	0.893545921910107	0.853694531487825	1
Mrps31	ENSMUSG00000031533	0.5155648232968	0.5155648232968	0.299349060054895	0.5155648232968	0.400265374208515	0.5155648232968
Mrps22	ENSMUSG00000032459	0.120545895661628	0.222173997210623	0.148115998140415	0.222173997210623	0.514300775319626	0.514300775319626
Mrps17	ENSMUSG00000034211	0.643853282854191	0.853049270252403	0.5155648232968	0.853049270252403	0.853049270252403	0.853049270252403
Mrpl41	ENSMUSG00000036850	0.853694531487825	0.853694531487825	0.146800541856249	0.440401625568746	0.399548817627028	0.599323226440542
Mrpl47	ENSMUSG00000037531	0.926003599371282	1	1	1	0.454942951775341	1
Mrpl50	ENSMUSG00000044018	0.400265374208515	0.600398061312773	0.348008842235184	0.600398061312773	0.781170242226513	0.781170242226513
Mrpl18	ENSMUSG00000057388	0.852504981253341	0.852504981253341	0.254414773803597	0.679320738524319	0.452880492349546	0.679320738524319
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Gspt1	ENSMUSG00000062203	0.78180291566155	0.853372965654504	0.853372965654504	0.853372965654504	0.78148726569172	0.853372965654504
Mrpl42	ENSMUSG00000062981	0.119631084167592	0.358893252502775	0.297095062262362	0.445642593393544	0.453570536021945	0.453570536021945
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995

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mRNA Splicing - Major Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrnp27	ENSMUSG00000001158	0.575536202757516	0.575536202757516	0.298599969973533	0.450143880930327	0.300095920620218	0.450143880930327
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Hnrnpa2b1	ENSMUSG00000004980	0.256271555563966	0.5155648232968	0.5155648232968	0.5155648232968	0.514300775319626	0.5155648232968
Snrpb2	ENSMUSG00000008333	0.92380865295296	0.92380865295296	0.511742979522636	0.92380865295296	0.637274134311157	0.92380865295296
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Cwc27	ENSMUSG00000021715	0.254414773803597	0.255901190956604	0.0166824765447319	0.0500474296341957	0.255901190956604	0.255901190956604
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Sf3a3	ENSMUSG00000028902	0.453225835454266	0.453225835454266	0.214037080764326	0.453225835454266	0.450444934184774	0.453225835454266
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Lsm6	ENSMUSG00000031683	0.78180291566155	0.78180291566155	0.711650020253571	0.78180291566155	0.578396848531894	0.78180291566155
Lsm3	ENSMUSG00000034192	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739	0.78180291566155	0.853801250889739
Rbmxl1	ENSMUSG00000037070	0.643359829732651	0.926441990075769	0.058823267388015	0.176469802164045	0.926441990075769	0.926441990075769
Txnl4a	ENSMUSG00000057130	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Ppih	ENSMUSG00000060288	0.578113371816017	0.965779924281287	0.643853282854191	0.965779924281287	1	1
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172

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Mitochondrial translation termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl32	ENSMUSG00000015672	0.255530331334266	0.383295497001398	0.252545530864481	0.383295497001398	0.514300775319626	0.514300775319626
Mrpl22	ENSMUSG00000020514	0.509798138101151	0.764697207151727	0.776919261684345	0.776919261684345	0.452880492349546	0.764697207151727
Mrrf	ENSMUSG00000026887	0.852940894477647	0.852940894477647	0.211110344399808	0.633331033199424	0.780851835278818	0.852940894477647
Mrpl46	ENSMUSG00000030612	1	1	0.297848640636702	0.893545921910107	0.853694531487825	1
Mrps31	ENSMUSG00000031533	0.5155648232968	0.5155648232968	0.299349060054895	0.5155648232968	0.400265374208515	0.5155648232968
Mrps22	ENSMUSG00000032459	0.120545895661628	0.222173997210623	0.148115998140415	0.222173997210623	0.514300775319626	0.514300775319626
Mrps17	ENSMUSG00000034211	0.643853282854191	0.853049270252403	0.5155648232968	0.853049270252403	0.853049270252403	0.853049270252403
Mrpl41	ENSMUSG00000036850	0.853694531487825	0.853694531487825	0.146800541856249	0.440401625568746	0.399548817627028	0.599323226440542
Mrpl47	ENSMUSG00000037531	0.926003599371282	1	1	1	0.454942951775341	1
Mrpl50	ENSMUSG00000044018	0.400265374208515	0.600398061312773	0.348008842235184	0.600398061312773	0.781170242226513	0.781170242226513
Mrpl18	ENSMUSG00000057388	0.852504981253341	0.852504981253341	0.254414773803597	0.679320738524319	0.452880492349546	0.679320738524319
Mrpl42	ENSMUSG00000062981	0.119631084167592	0.358893252502775	0.297095062262362	0.445642593393544	0.453570536021945	0.453570536021945

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Mitochondrial translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl32	ENSMUSG00000015672	0.255530331334266	0.383295497001398	0.252545530864481	0.383295497001398	0.514300775319626	0.514300775319626
Mrpl22	ENSMUSG00000020514	0.509798138101151	0.764697207151727	0.776919261684345	0.776919261684345	0.452880492349546	0.764697207151727
Mrrf	ENSMUSG00000026887	0.852940894477647	0.852940894477647	0.211110344399808	0.633331033199424	0.780851835278818	0.852940894477647
Mrpl46	ENSMUSG00000030612	1	1	0.297848640636702	0.893545921910107	0.853694531487825	1
Mrps31	ENSMUSG00000031533	0.5155648232968	0.5155648232968	0.299349060054895	0.5155648232968	0.400265374208515	0.5155648232968
Mrps22	ENSMUSG00000032459	0.120545895661628	0.222173997210623	0.148115998140415	0.222173997210623	0.514300775319626	0.514300775319626
Mrps17	ENSMUSG00000034211	0.643853282854191	0.853049270252403	0.5155648232968	0.853049270252403	0.853049270252403	0.853049270252403
Mrpl41	ENSMUSG00000036850	0.853694531487825	0.853694531487825	0.146800541856249	0.440401625568746	0.399548817627028	0.599323226440542
Mrpl47	ENSMUSG00000037531	0.926003599371282	1	1	1	0.454942951775341	1
Mrpl50	ENSMUSG00000044018	0.400265374208515	0.600398061312773	0.348008842235184	0.600398061312773	0.781170242226513	0.781170242226513
Mrpl18	ENSMUSG00000057388	0.852504981253341	0.852504981253341	0.254414773803597	0.679320738524319	0.452880492349546	0.679320738524319
Mrpl42	ENSMUSG00000062981	0.119631084167592	0.358893252502775	0.297095062262362	0.445642593393544	0.453570536021945	0.453570536021945

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mRNA Splicing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrnp27	ENSMUSG00000001158	0.575536202757516	0.575536202757516	0.298599969973533	0.450143880930327	0.300095920620218	0.450143880930327
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Hnrnpa2b1	ENSMUSG00000004980	0.256271555563966	0.5155648232968	0.5155648232968	0.5155648232968	0.514300775319626	0.5155648232968
Snrpb2	ENSMUSG00000008333	0.92380865295296	0.92380865295296	0.511742979522636	0.92380865295296	0.637274134311157	0.92380865295296
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Cwc27	ENSMUSG00000021715	0.254414773803597	0.255901190956604	0.0166824765447319	0.0500474296341957	0.255901190956604	0.255901190956604
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Sf3a3	ENSMUSG00000028902	0.453225835454266	0.453225835454266	0.214037080764326	0.453225835454266	0.450444934184774	0.453225835454266
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Lsm6	ENSMUSG00000031683	0.78180291566155	0.78180291566155	0.711650020253571	0.78180291566155	0.578396848531894	0.78180291566155
Lsm3	ENSMUSG00000034192	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739	0.78180291566155	0.853801250889739
Rbmxl1	ENSMUSG00000037070	0.643359829732651	0.926441990075769	0.058823267388015	0.176469802164045	0.926441990075769	0.926441990075769
Txnl4a	ENSMUSG00000057130	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Ppih	ENSMUSG00000060288	0.578113371816017	0.965779924281287	0.643853282854191	0.965779924281287	1	1
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172

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Mitochondrial translation elongation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl32	ENSMUSG00000015672	0.255530331334266	0.383295497001398	0.252545530864481	0.383295497001398	0.514300775319626	0.514300775319626
Mrpl22	ENSMUSG00000020514	0.509798138101151	0.764697207151727	0.776919261684345	0.776919261684345	0.452880492349546	0.764697207151727
Mrpl46	ENSMUSG00000030612	1	1	0.297848640636702	0.893545921910107	0.853694531487825	1
Mrps31	ENSMUSG00000031533	0.5155648232968	0.5155648232968	0.299349060054895	0.5155648232968	0.400265374208515	0.5155648232968
Mrps22	ENSMUSG00000032459	0.120545895661628	0.222173997210623	0.148115998140415	0.222173997210623	0.514300775319626	0.514300775319626
Mrps17	ENSMUSG00000034211	0.643853282854191	0.853049270252403	0.5155648232968	0.853049270252403	0.853049270252403	0.853049270252403
Mrpl41	ENSMUSG00000036850	0.853694531487825	0.853694531487825	0.146800541856249	0.440401625568746	0.399548817627028	0.599323226440542
Mrpl47	ENSMUSG00000037531	0.926003599371282	1	1	1	0.454942951775341	1
Mrpl50	ENSMUSG00000044018	0.400265374208515	0.600398061312773	0.348008842235184	0.600398061312773	0.781170242226513	0.781170242226513
Mrpl18	ENSMUSG00000057388	0.852504981253341	0.852504981253341	0.254414773803597	0.679320738524319	0.452880492349546	0.679320738524319
Mrpl42	ENSMUSG00000062981	0.119631084167592	0.358893252502775	0.297095062262362	0.445642593393544	0.453570536021945	0.453570536021945

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Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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APC/C-mediated degradation of cell cycle proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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Regulation of mitotic cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651

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Association of TriC/CCT with target proteins during biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cct5	ENSMUSG00000022234	0.347639524025037	0.521459286037555	0.148115998140416	0.444347994421247	1	1
Cct8	ENSMUSG00000025613	0.92622377157404	1	0.781170242226513	1	1	1
Cct2	ENSMUSG00000034024	0.926550375688041	0.926550375688041	0.255901190956604	0.767703572869812	0.643359829732651	0.926550375688041
Tcp1	ENSMUSG00000068039	0.449391287230099	0.674086930845148	0.924286968561133	0.924286968561133	0.445116333668945	0.674086930845148

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Metabolism of proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ltbp1	ENSMUSG00000001870	1	1	0.148772260628989	0.446316781886968	0.300095920620218	0.450143880930327
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Mrpl32	ENSMUSG00000015672	0.255530331334266	0.383295497001398	0.252545530864481	0.383295497001398	0.514300775319626	0.514300775319626
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90b1	ENSMUSG00000020048	0.148772260628989	0.223158390943484	0.146141353215796	0.223158390943484	0.640861491578951	0.640861491578951
Mrpl22	ENSMUSG00000020514	0.509798138101151	0.764697207151727	0.776919261684345	0.776919261684345	0.452880492349546	0.764697207151727
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Uchl3	ENSMUSG00000022111	0.577829325134931	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171
Dcaf11	ENSMUSG00000022214	0.782117202022501	0.782117202022501	0.576973746230334	0.782117202022501	0.643853282854191	0.782117202022501
Cct5	ENSMUSG00000022234	0.347639524025037	0.521459286037555	0.148115998140416	0.444347994421247	1	1
Ppara	ENSMUSG00000022383	0.505838378028518	0.575536202757516	0.21549027811633	0.575536202757516	0.575536202757516	0.575536202757516
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Klhl22	ENSMUSG00000022750	0.179249687218049	0.537749061654148	0.926550375688041	1	1	1
Btbd1	ENSMUSG00000025103	0.514934023620344	0.772401035430517	0.0953125666339397	0.285937699901819	0.926550375688041	0.926550375688041
Cct8	ENSMUSG00000025613	0.92622377157404	1	0.781170242226513	1	1	1
Usp16	ENSMUSG00000025616	0.853694531487825	1	0.180293335960318	0.540880007880955	1	1
Rab40c	ENSMUSG00000025730	0.853801250889739	0.853801250889739	0.0449262652924809	0.134778795877443	0.514934023620345	0.772401035430517
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Eif5b	ENSMUSG00000026083	0.639337105615664	0.639337105615664	0.298599969973533	0.597162263671263	0.398108175780842	0.597162263671263
Mrrf	ENSMUSG00000026887	0.852940894477647	0.852940894477647	0.211110344399808	0.633331033199424	0.780851835278818	0.852940894477647
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Galnt3	ENSMUSG00000026994	0.115651627788147	0.173477441682221	0.0164739112492867	0.0494217337478602	0.398108175780842	0.398108175780842
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375
Mrpl46	ENSMUSG00000030612	1	1	0.297848640636702	0.893545921910107	0.853694531487825	1
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Mrps31	ENSMUSG00000031533	0.5155648232968	0.5155648232968	0.299349060054895	0.5155648232968	0.400265374208515	0.5155648232968
Polb	ENSMUSG00000031536	0.120850531362929	0.321055621146488	0.214037080764326	0.321055621146488	0.853801250889739	0.853801250889739
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Mrps22	ENSMUSG00000032459	0.120545895661628	0.222173997210623	0.148115998140415	0.222173997210623	0.514300775319626	0.514300775319626
Cct2	ENSMUSG00000034024	0.926550375688041	0.926550375688041	0.255901190956604	0.767703572869812	0.643359829732651	0.926550375688041
Mrps17	ENSMUSG00000034211	0.643853282854191	0.853049270252403	0.5155648232968	0.853049270252403	0.853049270252403	0.853049270252403
Spcs2	ENSMUSG00000035227	0.849805525376199	0.853801250889739	0.853801250889739	0.853801250889739	0.248769231421035	0.746307694263104
Alg8	ENSMUSG00000035704	0.853694531487825	0.853694531487825	0.711650020253571	0.853694531487825	0.711650020253571	0.853694531487825
Calm2	ENSMUSG00000036438	0.0733738589968007	0.220121576990402	0.213307944885796	0.299349060054895	0.299349060054895	0.299349060054895
Mrpl41	ENSMUSG00000036850	0.853694531487825	0.853694531487825	0.146800541856249	0.440401625568746	0.399548817627028	0.599323226440542
Mrpl47	ENSMUSG00000037531	0.926003599371282	1	1	1	0.454942951775341	1
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Nsmce4a	ENSMUSG00000040331	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.399548817627028	0.926550375688041
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Mrpl50	ENSMUSG00000044018	0.400265374208515	0.600398061312773	0.348008842235184	0.600398061312773	0.781170242226513	0.781170242226513
Nanp	ENSMUSG00000053916	0.926441990075769	0.926441990075769	0.179945789077372	0.539837367232115	0.926333123228344	0.926441990075769
Mrpl18	ENSMUSG00000057388	0.852504981253341	0.852504981253341	0.254414773803597	0.679320738524319	0.452880492349546	0.679320738524319
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172
Gspt1	ENSMUSG00000062203	0.78180291566155	0.853372965654504	0.853372965654504	0.853372965654504	0.78148726569172	0.853372965654504
Mrpl42	ENSMUSG00000062981	0.119631084167592	0.358893252502775	0.297095062262362	0.445642593393544	0.453570536021945	0.453570536021945
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995
Tcp1	ENSMUSG00000068039	0.449391287230099	0.674086930845148	0.924286968561133	0.924286968561133	0.445116333668945	0.674086930845148
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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C-type lectin receptors (CLRs)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Raf1	ENSMUSG00000000441	0.0936419271039908	0.142133847148433	0.0947558980989551	0.142133847148433	0.255530331334266	0.255530331334266
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Calm2	ENSMUSG00000036438	0.0733738589968007	0.220121576990402	0.213307944885796	0.299349060054895	0.299349060054895	0.299349060054895
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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MAPK6/MAPK4 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Etv4	ENSMUSG00000017724	0.17924968721805	0.518116419532656	0.92622377157404	0.92622377157404	0.345410946355104	0.518116419532656
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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CLEC7A (Dectin-1) signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Calm2	ENSMUSG00000036438	0.0733738589968007	0.220121576990402	0.213307944885796	0.299349060054895	0.299349060054895	0.299349060054895
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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SLBP independent Processing of Histone Pre-mRNAs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517

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Interleukin-1 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Hmgb1	ENSMUSG00000066551	0.853372965654504	0.853372965654504	0.21549027811633	0.323235417174495	0.178901132102685	0.323235417174495
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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CDT1 association with the CDC6:ORC:origin complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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G2/M Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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The role of GTSE1 in G2/M progression after G2 checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Mitotic G2-G2/M phases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517

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Transcriptional regulation by RUNX2

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Anp32a	ENSMUSG00000032249	0.852940894477647	0.852940894477647	0.852832278580641	0.852940894477647	0.454600801949285	0.852940894477647
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Exosc1	ENSMUSG00000034321	0.853372965654504	0.853372965654504	0.0741204440774082	0.222361332232225	0.853372965654504	0.853372965654504
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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RUNX1 regulates transcription of genes involved in differentiation of HSCs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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Assembly of the pre-replicative complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Interleukin-1 family signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Hmgb1	ENSMUSG00000066551	0.853372965654504	0.853372965654504	0.21549027811633	0.323235417174495	0.178901132102685	0.323235417174495
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Regulation of RUNX2 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Ubiquitin-dependent degradation of Cyclin D

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nhp2	ENSMUSG00000001056	0.578113371816017	0.578113371816017	0.148115998140416	0.444347994421247	0.454600801949285	0.578113371816017
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Dscc1	ENSMUSG00000022422	0.782117202022501	0.782117202022501	0.250285839267991	0.519791938509652	0.346527959006435	0.519791938509652
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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p53-Independent DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Autodegradation of the E3 ubiquitin ligase COP1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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p53-Independent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Orc1 removal from chromatin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Degradation of AXIN

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Regulation of RUNX3 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Cyclin E associated events during G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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Cell Cycle Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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M Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Formation of Incision Complex in GG-NER

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Xpa	ENSMUSG00000028329	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.348008842235184	0.853480389728993
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Stabilization of p53

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Cyclin A:Cdk2-associated events at S phase entry

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Degradation of GLI1 by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Downstream signaling events of B Cell Receptor (BCR)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Calm2	ENSMUSG00000036438	0.0733738589968007	0.220121576990402	0.213307944885796	0.299349060054895	0.299349060054895	0.299349060054895
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Degradation of DVL

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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NIK–>noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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GLI3 is processed to GLI3R by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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G2/M Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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ABC-family proteins mediated transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Abcc6	ENSMUSG00000030834	0.853049270252403	0.853049270252403	0.120850531362929	0.362551594088788	0.348008842235184	0.522013263352777
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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SCF(Skp2)-mediated degradation of p27/p21

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Asymmetric localization of PCP proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Activation of NF-kappaB in B cells

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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DNA Replication Pre-Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Recycling of eIF2:GDP

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375

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snRNP Assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Snupn	ENSMUSG00000055334	0.45596561163947	0.45596561163947	0.120545895661627	0.361637686984882	0.45596561163947	0.45596561163947

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Hedgehog ligand biogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Metabolism of non-coding RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Snupn	ENSMUSG00000055334	0.45596561163947	0.45596561163947	0.120545895661627	0.361637686984882	0.45596561163947	0.45596561163947

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Cell Cycle, Mitotic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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G1/S Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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Mitotic G1 phase and G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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mRNA Splicing - Minor Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpd1	ENSMUSG00000002477	0.78148726569172	0.78148726569172	0.711240436189781	0.78148726569172	0.398108175780842	0.78148726569172
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Txnl4a	ENSMUSG00000057130	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155

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p53-Dependent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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p53-Dependent G1 DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Cross-presentation of soluble exogenous antigens (endosomes)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Regulation of RAS by GAPs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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APC/C:Cdc20 mediated degradation of Securin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Separation of Sister Chromatids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026

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G1/S DNA Damage Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transport of the SLBP independent Mature mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891

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Regulation of ornithine decarboxylase (ODC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transport of the SLBP Dependant Mature mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891

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Cellular response to hypoxia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Switching of origins to a post-replicative state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Regulation of PTEN stability and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Downstream TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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RNA Polymerase II Pre-transcription Events

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ssrp1	ENSMUSG00000027067	0.850721744111585	0.850721744111585	0.0763619660358786	0.229085898107636	0.297848640636702	0.446772960955053
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Taf12	ENSMUSG00000028899	0.926441990075769	1	1	1	0.78180291566155	1
Gtf2e2	ENSMUSG00000031585	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	0.78148726569172	0.78148726569172
Taf9	ENSMUSG00000052293	1	1	0.0331400397096514	0.0994201191289543	0.710001140920767	1
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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CDK-mediated phosphorylation and removal of Cdc6

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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UCH proteinases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Uchl3	ENSMUSG00000022111	0.577829325134931	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Mitotic Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026

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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Mitotic Metaphase and Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026

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BBSome-mediated cargo-targeting to cilium

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cct5	ENSMUSG00000022234	0.347639524025037	0.521459286037555	0.148115998140416	0.444347994421247	1	1
Cct8	ENSMUSG00000025613	0.92622377157404	1	0.781170242226513	1	1	1
Cct2	ENSMUSG00000034024	0.926550375688041	0.926550375688041	0.255901190956604	0.767703572869812	0.643359829732651	0.926550375688041
Tcp1	ENSMUSG00000068039	0.449391287230099	0.674086930845148	0.924286968561133	0.924286968561133	0.445116333668945	0.674086930845148

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Transport of Mature Transcript to Cytoplasm

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Sarnp	ENSMUSG00000078427	0.256271555563966	0.514934023620345	0.514934023620345	0.514934023620345	0.452880492349546	0.514934023620345

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Degradation of beta-catenin by the destruction complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transcriptional regulation by RUNX3

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transport of Mature mRNA Derived from an Intronless Transcript

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891

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Metabolism of polyamines

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transport of Mature mRNAs Derived from Intronless Transcripts

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891

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Hedgehog ‘on’ state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Regulation of PLK1 Activity at G2/M Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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RNA Polymerase II Transcription Termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Sarnp	ENSMUSG00000078427	0.256271555563966	0.514934023620345	0.514934023620345	0.514934023620345	0.452880492349546	0.514934023620345

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Mitotic Prometaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Nuf2	ENSMUSG00000026683	1	1	0.0548979200435556	0.164693760130667	0.92622377157404	1
Mad2l1	ENSMUSG00000029910	0.926550375688041	0.926550375688041	0.0325051220296005	0.0975153660888015	0.5155648232968	0.7733472349452
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Bub3	ENSMUSG00000066979	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651	0.578396848531894	0.643359829732651
Spc24	ENSMUSG00000074476	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026	0.148772260628989	0.392985378348026

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TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Loss of Nlp from mitotic centrosomes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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Transcriptional regulation by RUNX1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Ctsl	ENSMUSG00000021477	0.852832278580641	0.852832278580641	0.711240436189781	0.852832278580641	0.852832278580641	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Smarce1	ENSMUSG00000037935	0.572616808177226	0.572616808177226	0.0592616003460512	0.177784801038154	0.511097249598474	0.572616808177226
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Hist1h2bb	ENSMUSG00000075031	0.11472987636036	0.17715513584223	0.852832278580641	0.852832278580641	0.11810342389482	0.17715513584223

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Loss of proteins required for interphase microtubule organization from the centrosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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Processing of Capped Intronless Pre-mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Snrpf	ENSMUSG00000020018	0.570836132666921	0.643359829732651	0.643359829732651	0.643359829732651	0.299349060054895	0.643359829732651
Snrpd3	ENSMUSG00000020180	0.180293335960318	0.398108175780842	0.398108175780842	0.398108175780842	0.298599969973533	0.398108175780842
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517

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PTEN Regulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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PCP/CE pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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TAK1 activates NFkB by phosphorylation and activation of IKKs complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Hmgb1	ENSMUSG00000066551	0.853372965654504	0.853372965654504	0.21549027811633	0.323235417174495	0.178901132102685	0.323235417174495
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Neddylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Uchl3	ENSMUSG00000022111	0.577829325134931	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171	0.711034989117171
Dcaf11	ENSMUSG00000022214	0.782117202022501	0.782117202022501	0.576973746230334	0.782117202022501	0.643853282854191	0.782117202022501
Klhl22	ENSMUSG00000022750	0.179249687218049	0.537749061654148	0.926550375688041	1	1	1
Btbd1	ENSMUSG00000025103	0.514934023620344	0.772401035430517	0.0953125666339397	0.285937699901819	0.926550375688041	0.926550375688041
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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AURKA Activation by TPX2

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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Cilium Assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cct5	ENSMUSG00000022234	0.347639524025037	0.521459286037555	0.148115998140416	0.444347994421247	1	1
Cct8	ENSMUSG00000025613	0.92622377157404	1	0.781170242226513	1	1	1
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Cct2	ENSMUSG00000034024	0.926550375688041	0.926550375688041	0.255901190956604	0.767703572869812	0.643359829732651	0.926550375688041
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133
Dynlrb1	ENSMUSG00000047459	0.451840588205062	0.451840588205062	0.449391287230099	0.451840588205062	0.348008842235184	0.451840588205062
Tcp1	ENSMUSG00000068039	0.449391287230099	0.674086930845148	0.924286968561133	0.924286968561133	0.445116333668945	0.674086930845148

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Synthesis of DNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Transport of Mature mRNA derived from an Intron-Containing Transcript

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Ncbp2	ENSMUSG00000022774	0.297095062262363	0.517556086579331	0.345037391052887	0.517556086579331	0.852504981253341	0.852504981253341
Thoc1	ENSMUSG00000024287	0.254414773803597	0.381622160705395	0.214037080764326	0.381622160705395	0.706831781264721	0.706831781264721
Ncbp1	ENSMUSG00000028330	0.853372965654504	0.853372965654504	0.346899083932133	0.772401035430517	0.514934023620345	0.772401035430517
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Sarnp	ENSMUSG00000078427	0.256271555563966	0.514934023620345	0.514934023620345	0.514934023620345	0.452880492349546	0.514934023620345

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S Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403

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Eukaryotic Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Eif5b	ENSMUSG00000026083	0.639337105615664	0.639337105615664	0.298599969973533	0.597162263671263	0.398108175780842	0.597162263671263
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995

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Cap-dependent Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif2s1	ENSMUSG00000021116	0.514934023620345	0.772401035430517	0.0741204440774082	0.222361332232225	0.78180291566155	0.78180291566155
Eif5b	ENSMUSG00000026083	0.639337105615664	0.639337105615664	0.298599969973533	0.597162263671263	0.398108175780842	0.597162263671263
Eif4e	ENSMUSG00000028156	0.643853282854191	0.643853282854191	0.34837756124189	0.643853282854191	0.456305241393103	0.643853282854191
Eif2b3	ENSMUSG00000028683	0.578113371816017	0.643853282854191	0.346527959006435	0.643853282854191	0.643853282854191	0.643853282854191
Eif2b4	ENSMUSG00000029145	0.566285712787375	0.566285712787375	0.11595859961889	0.347875798856669	0.451840588205062	0.566285712787375
Rpl5	ENSMUSG00000058558	0.255901190956604	0.711034989117171	0.708745765211584	0.711034989117171	0.711034989117171	0.711034989117171
Rpl35	ENSMUSG00000062997	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.399548817627028	0.643359829732651
Rpl27	ENSMUSG00000063316	0.146800541856249	0.216214347033995	0.0958690133561599	0.216214347033995	0.216214347033995	0.216214347033995

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TNFR2 non-canonical NF-kB pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Global Genome Nucleotide Excision Repair (GG-NER)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Xpa	ENSMUSG00000028329	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.348008842235184	0.853480389728993
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Centrosome maturation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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Recruitment of mitotic centrosome proteins and complexes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdk1	ENSMUSG00000019942	1	1	0.113190884633071	0.339572653899213	0.853694531487825	1
Hsp90aa1	ENSMUSG00000021270	0.147458757705094	0.442231101684348	0.294820734456232	0.442231101684348	0.709375484777034	0.709375484777034
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Haus7	ENSMUSG00000031371	0.342026805366747	0.5155648232968	0.346527959006435	0.5155648232968	0.5155648232968	0.5155648232968
Cep63	ENSMUSG00000032534	0.643853282854191	0.926658283600152	0.926658283600152	0.926658283600152	0.782117202022501	0.926658283600152
Haus8	ENSMUSG00000035439	0.924286968561133	0.924286968561133	0.0761127945805735	0.228338383741721	0.766080166042519	0.924286968561133

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DNA Replication

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Orc2	ENSMUSG00000026037	0.852832278580641	0.852832278580641	0.393724994268831	0.852832278580641	0.78180291566155	0.852832278580641
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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Nucleotide Excision Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Xpa	ENSMUSG00000028329	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.348008842235184	0.853480389728993
Isy1	ENSMUSG00000030056	0.348008842235184	0.710208797518812	0.640861491578951	0.710208797518812	0.710208797518812	0.710208797518812
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Cdk7	ENSMUSG00000069089	0.711650020253571	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Antigen processing: Ubiquitination & Proteasome degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Ube2v2	ENSMUSG00000022674	0.120850531362929	0.362551594088788	0.514934023620345	0.514934023620345	0.399548817627028	0.514934023620345
Klhl22	ENSMUSG00000022750	0.179249687218049	0.537749061654148	0.926550375688041	1	1	1
Btbd1	ENSMUSG00000025103	0.514934023620344	0.772401035430517	0.0953125666339397	0.285937699901819	0.926550375688041	0.926550375688041
Rnf25	ENSMUSG00000026171	0.782117202022501	0.782117202022501	0.78180291566155	0.782117202022501	0.395196379647461	0.782117202022501
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Mib2	ENSMUSG00000029060	0.299349060054895	0.299349060054895	0.0241933715424143	0.0725801146272428	0.146800541856249	0.220200812784373
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173
Hectd3	ENSMUSG00000046861	0.643853282854191	0.643853282854191	0.254414773803597	0.520348625898199	0.346899083932133	0.520348625898199
Ube2n	ENSMUSG00000074781	0.398108175780842	0.45596561163947	0.45596561163947	0.45596561163947	0.398829756175299	0.45596561163947

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Ub-specific processing proteases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmc3	ENSMUSG00000002102	0.575536202757516	0.575536202757516	0.0331400397096515	0.0994201191289545	0.514300775319626	0.575536202757516
Ubb	ENSMUSG00000019505	0.454942951775341	0.454942951775341	0.0756145297453648	0.226843589236094	0.300095920620218	0.450143880930327
Psmd12	ENSMUSG00000020720	0.577829325134931	0.866743987702397	0.255901190956603	0.76770357286981	1	1
Psmc1	ENSMUSG00000021178	0.926003599371282	0.926003599371282	0.11595859961889	0.173937899428334	0.0766111619812296	0.173937899428334
Tab1	ENSMUSG00000022414	0.0447373296833729	0.111180666116112	0.0741204440774082	0.111180666116112	0.348008842235184	0.348008842235184
Usp16	ENSMUSG00000025616	0.853694531487825	1	0.180293335960318	0.540880007880955	1	1
Psmd14	ENSMUSG00000026914	0.852175490580835	0.852175490580835	0.569937449249116	0.852175490580835	0.575536202757516	0.852175490580835
Polb	ENSMUSG00000031536	0.120850531362929	0.321055621146488	0.214037080764326	0.321055621146488	0.853801250889739	0.853801250889739
Psma4	ENSMUSG00000032301	0.711650020253571	0.711650020253571	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173
Psmd7	ENSMUSG00000039067	1	1	0.17750354896016	0.532510646880481	0.455625354715449	0.683438032073173

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SUMO E3 ligases SUMOylate target proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tpr	ENSMUSG00000006005	0.346899083932133	0.522013263352776	0.348008842235184	0.522013263352776	0.853694531487825	0.853694531487825
Birc5	ENSMUSG00000017716	0.144157978128025	0.317766870502212	0.711650020253571	0.711650020253571	0.211844580334808	0.317766870502212
Ppara	ENSMUSG00000022383	0.505838378028518	0.575536202757516	0.21549027811633	0.575536202757516	0.575536202757516	0.575536202757516
Nop58	ENSMUSG00000026020	0.454600801949285	0.681901202923927	0.0230207752632622	0.0690623257897866	0.711650020253571	0.711650020253571
Hdac1	ENSMUSG00000028800	0.78180291566155	0.78180291566155	0.11993617140438	0.359808514213139	0.456305241393103	0.684457862089655
Cetn2	ENSMUSG00000031347	0.782117202022501	0.853372965654504	0.78148726569172	0.853372965654504	0.853372965654504	0.853372965654504
Nsmce4a	ENSMUSG00000040331	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.399548817627028	0.926550375688041
Nup88	ENSMUSG00000040667	0.569937449249116	0.569937449249116	0.0761127945805736	0.228338383741721	0.214764523938594	0.322146785907891
Hnrnpc	ENSMUSG00000060373	0.300095920620218	0.78148726569172	0.640355507848752	0.78148726569172	0.78148726569172	0.78148726569172

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antiquewhite2

Ribosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps5	ENSMUSG00000012848	0.148772260628989	0.446316781886968	0.511742979522636	0.767614469283954	0.926658283600152	0.926658283600152
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rpl10a	ENSMUSG00000037805	0.454942951775342	0.926550375688041	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041
Fau	ENSMUSG00000038274	0.0703913497478893	0.211174049243668	0.177153312234059	0.265729968351089	0.711854160331342	0.711854160331342
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl36	ENSMUSG00000057863	0.180293335960318	0.449023590082343	0.299349060054895	0.449023590082343	0.853694531487825	0.853694531487825
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Rpl41	ENSMUSG00000093674	0.340887582990546	0.703556284613037	0.703556284613037	0.703556284613037	0.57113445032749	0.703556284613037
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Coronavirus disease - COVID-19

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps5	ENSMUSG00000012848	0.148772260628989	0.446316781886968	0.511742979522636	0.767614469283954	0.926658283600152	0.926658283600152
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Masp1	ENSMUSG00000022887	0.348008842235184	0.599861112226622	0.399907408151081	0.599861112226622	0.926496242814507	0.926496242814507
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Casp1	ENSMUSG00000025888	0.390750658104794	0.505169133438821	0.0969812105731561	0.290943631719468	0.505169133438821	0.505169133438821
Ifih1	ENSMUSG00000026896	0.778911768167544	0.778911768167544	0.00477055016690543	0.0143116505007163	0.709375484777034	0.778911768167544
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
C8b	ENSMUSG00000029656	0.85326530496423	0.85326530496423	0.00273940240699959	0.00821820722099877	0.211477675547592	0.317216513321387
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Ccl12	ENSMUSG00000035352	0.0226344734406829	0.0679034203220487	0.853372965654504	0.853372965654504	0.180293335960318	0.270440003940477
Isg15	ENSMUSG00000035692	0.00463747559282086	0.0139124267784626	0.711650020253571	0.711650020253571	0.5155648232968	0.711650020253571
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rpl10a	ENSMUSG00000037805	0.454942951775342	0.926550375688041	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041
Fau	ENSMUSG00000038274	0.0703913497478893	0.211174049243668	0.177153312234059	0.265729968351089	0.711854160331342	0.711854160331342
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Jun	ENSMUSG00000052684	0.0241933715424143	0.0725801146272428	0.853907737111068	0.853907737111068	0.299349060054895	0.449023590082343
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl36	ENSMUSG00000057863	0.180293335960318	0.449023590082343	0.299349060054895	0.449023590082343	0.853694531487825	0.853694531487825
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Rpl41	ENSMUSG00000093674	0.340887582990546	0.703556284613037	0.703556284613037	0.703556284613037	0.57113445032749	0.703556284613037
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Huntington disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ap2s1	ENSMUSG00000008036	0.0328221470541517	0.0492332205812275	0.0232795908282423	0.0492332205812275	0.293293089483362	0.293293089483362
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Ap2m1	ENSMUSG00000022841	0.513665062682276	0.513665062682276	0.17433930265919	0.513665062682276	0.508488713161374	0.513665062682276
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Creb3l1	ENSMUSG00000027230	0.453225835454266	0.679838753181399	0.853372965654504	0.853372965654504	0.348008842235184	0.679838753181399
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Creb3	ENSMUSG00000028466	0.0936419271039908	0.280925781311972	0.92589277149125	0.92589277149125	0.509798138101151	0.764697207151727
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
9430023L20Rik	ENSMUSG00000037204	0.068655014038086	0.205965042114258	0.138156294413154	0.207234441619731	0.398108175780842	0.398108175780842
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

Download data as csv

Amyotrophic lateral sclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Bid	ENSMUSG00000004446	0.299349060054895	0.449023590082343	0.92589277149125	0.92589277149125	0.253294730253594	0.449023590082343
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Nxf2	ENSMUSG00000009941	0.923687650871648	0.923687650871648	0.0313100870169898	0.0939302610509693	0.923687650871648	0.923687650871648
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Rab5a	ENSMUSG00000017831	0.256271555563966	0.299349060054895	0.255901190956604	0.299349060054895	0.299349060054895	0.299349060054895
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Srsf7	ENSMUSG00000024097	0.578396848531894	0.926658283600152	0.926658283600152	0.926658283600152	0.710001140920767	0.926658283600152
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Casp1	ENSMUSG00000025888	0.390750658104794	0.505169133438821	0.0969812105731561	0.290943631719468	0.505169133438821	0.505169133438821
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
3110043O21Rik	ENSMUSG00000028300	0.926333123228344	0.926658283600152	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Rab39b	ENSMUSG00000031202	0.712057867818062	0.853801250889739	0.454600801949285	0.853801250889739	0.853801250889739	0.853801250889739
Gabarapl2	ENSMUSG00000031950	0.213307944885796	0.319961917328694	0.0426702157436794	0.128010647231038	0.641867098978198	0.641867098978198
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
9430023L20Rik	ENSMUSG00000037204	0.068655014038086	0.205965042114258	0.138156294413154	0.207234441619731	0.398108175780842	0.398108175780842
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Atxn2	ENSMUSG00000042605	0.146141353215796	0.219212029823693	0.146141353215796	0.219212029823693	0.643853282854191	0.643853282854191
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Vapb	ENSMUSG00000054455	0.179945789077372	0.383851786434906	0.708534948098331	0.708534948098331	0.255901190956604	0.383851786434906
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Nrg1	ENSMUSG00000062991	0.513665062682276	0.926003599371282	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544

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Oxidative phosphorylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Atp6v1f	ENSMUSG00000004285	0.0523032931247597	0.156909879374279	0.208897379073412	0.313346068610118	0.641867098978198	0.641867098978198
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Atp6v0e	ENSMUSG00000015575	0.509144723230069	0.763717084845103	0.92416823462528	0.92416823462528	0.386972299618399	0.763717084845103
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Atp6v1h	ENSMUSG00000033793	0.0548979200435555	0.164693760130667	0.161774914569557	0.242662371854336	0.346899083932133	0.346899083932133
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

Download data as csv

Parkinson disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ube2j1	ENSMUSG00000028277	0.711240436189781	0.926658283600152	0.926658283600152	0.926658283600152	0.0166824765447319	0.0500474296341958
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Calml4	ENSMUSG00000032246	0.573498913947369	0.573498913947369	0.118714930081337	0.223158390943484	0.148772260628989	0.223158390943484
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

Download data as csv

Thermogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Rps6ka2	ENSMUSG00000023809	0.299349060054895	0.299349060054895	0.177153312234059	0.265729968351089	0.148115998140415	0.265729968351089
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Atf2	ENSMUSG00000027104	0.174692232033629	0.321055621146488	0.852175490580835	0.852175490580835	0.214037080764326	0.321055621146488
Creb3l1	ENSMUSG00000027230	0.453225835454266	0.679838753181399	0.853372965654504	0.853372965654504	0.348008842235184	0.679838753181399
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Creb3	ENSMUSG00000028466	0.0936419271039908	0.280925781311972	0.92589277149125	0.92589277149125	0.509798138101151	0.764697207151727
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Slc25a20	ENSMUSG00000032602	0.0116356061791785	0.0349068185375355	0.853907737111068	0.926658283600152	0.926658283600152	0.926658283600152
Sos2	ENSMUSG00000034801	0.044737329683373	0.134211989050119	0.513026869856283	0.769540304784424	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufaf3	ENSMUSG00000070283	0.0441715176243982	0.132514552873195	0.399548817627028	0.573498913947369	0.573498913947369	0.573498913947369
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
1810043H04Rik	ENSMUSG00000078572	0.146141353215796	0.219212029823693	0.0579478375430677	0.173843512629203	0.511742979522636	0.511742979522636
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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Prion disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Ncam2	ENSMUSG00000022762	0.00468160475316412	0.0140448142594924	0.173986036612496	0.17924968721805	0.17924968721805	0.17924968721805
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Atf2	ENSMUSG00000027104	0.174692232033629	0.321055621146488	0.852175490580835	0.852175490580835	0.214037080764326	0.321055621146488
Creb3l1	ENSMUSG00000027230	0.453225835454266	0.679838753181399	0.853372965654504	0.853372965654504	0.348008842235184	0.679838753181399
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Creb3	ENSMUSG00000028466	0.0936419271039908	0.280925781311972	0.92589277149125	0.92589277149125	0.509798138101151	0.764697207151727
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
C8b	ENSMUSG00000029656	0.85326530496423	0.85326530496423	0.00273940240699959	0.00821820722099877	0.211477675547592	0.317216513321387
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

Download data as csv

Pathways of neurodegeneration - multiple diseases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Bid	ENSMUSG00000004446	0.299349060054895	0.449023590082343	0.92589277149125	0.92589277149125	0.253294730253594	0.449023590082343
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Rab5a	ENSMUSG00000017831	0.256271555563966	0.299349060054895	0.255901190956604	0.299349060054895	0.299349060054895	0.299349060054895
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Hsd17b10	ENSMUSG00000025260	0.926333123228344	0.926333123228344	0.925444427431699	0.926333123228344	0.57466664340579	0.926333123228344
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ube2j1	ENSMUSG00000028277	0.711240436189781	0.926658283600152	0.926658283600152	0.926658283600152	0.0166824765447319	0.0500474296341958
3110043O21Rik	ENSMUSG00000028300	0.926333123228344	0.926658283600152	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Rab39b	ENSMUSG00000031202	0.712057867818062	0.853801250889739	0.454600801949285	0.853801250889739	0.853801250889739	0.853801250889739
Gabarapl2	ENSMUSG00000031950	0.213307944885796	0.319961917328694	0.0426702157436794	0.128010647231038	0.641867098978198	0.641867098978198
Calml4	ENSMUSG00000032246	0.573498913947369	0.573498913947369	0.118714930081337	0.223158390943484	0.148772260628989	0.223158390943484
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
9430023L20Rik	ENSMUSG00000037204	0.068655014038086	0.205965042114258	0.138156294413154	0.207234441619731	0.398108175780842	0.398108175780842
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Atxn2	ENSMUSG00000042605	0.146141353215796	0.219212029823693	0.146141353215796	0.219212029823693	0.643853282854191	0.643853282854191
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Vapb	ENSMUSG00000054455	0.179945789077372	0.383851786434906	0.708534948098331	0.708534948098331	0.255901190956604	0.383851786434906
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

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Non-alcoholic fatty liver disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Bid	ENSMUSG00000004446	0.299349060054895	0.449023590082343	0.92589277149125	0.92589277149125	0.253294730253594	0.449023590082343
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Jun	ENSMUSG00000052684	0.0241933715424143	0.0725801146272428	0.853907737111068	0.853907737111068	0.299349060054895	0.449023590082343
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

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Metabolic pathways

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Srr	ENSMUSG00000001323	0.17924968721805	0.450143880930327	0.300095920620218	0.450143880930327	0.711854160331342	0.711854160331342
Idh3g	ENSMUSG00000002010	0.252545530864481	0.683948417459205	0.45596561163947	0.683948417459205	0.853694531487825	0.853694531487825
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Uck1	ENSMUSG00000002550	0.00270924971713393	0.00812774915140178	0.0113089139751576	0.0169633709627363	0.705968934865368	0.705968934865368
Prodh	ENSMUSG00000003526	0.024062085667391	0.0721862570021729	0.348008842235184	0.522013263352776	0.852832278580641	0.852832278580641
Gcdh	ENSMUSG00000003809	0.782117202022501	0.782117202022501	0.456305241393103	0.782117202022501	0.578113371816017	0.782117202022501
Nqo1	ENSMUSG00000003849	0.214764523938594	0.644293571815781	1	1	0.853480389728993	1
Atp6v1f	ENSMUSG00000004285	0.0523032931247597	0.156909879374279	0.208897379073412	0.313346068610118	0.641867098978198	0.641867098978198
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Pafah1b3	ENSMUSG00000005447	0.0166824765447319	0.0500474296341958	0.513665062682276	0.770497594023414	0.853372965654504	0.853372965654504
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Aprt	ENSMUSG00000006589	0.0443599545252852	0.0882349010820225	0.058823267388015	0.0882349010820225	0.782117202022501	0.782117202022501
Rdh13	ENSMUSG00000008435	1	1	0.926003599371282	1	0.094755898098955	0.284267694296865
Mgst1	ENSMUSG00000008540	0.0969812105731562	0.290943631719469	0.514934023620345	0.711034989117171	0.711034989117171	0.711034989117171
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Acyp1	ENSMUSG00000008822	0.57466664340579	0.853049270252403	0.509798138101151	0.853049270252403	0.853049270252403	0.853049270252403
Fpgs	ENSMUSG00000009566	0.0936419271039908	0.280925781311972	0.924987846321933	0.924987846321933	0.342026805366747	0.513040208050121
Pdhx	ENSMUSG00000010914	0.452880492349546	0.452880492349546	0.452880492349546	0.452880492349546	0.11810342389482	0.354310271684459
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Dguok	ENSMUSG00000014554	0.853480389728993	0.926550375688041	0.216214347033995	0.648643041101984	0.926550375688041	0.926550375688041
Atp6v0e	ENSMUSG00000015575	0.509144723230069	0.763717084845103	0.92416823462528	0.92416823462528	0.386972299618399	0.763717084845103
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
B4galt5	ENSMUSG00000017929	0.78148726569172	0.78180291566155	0.638310022345193	0.78180291566155	0.78180291566155	0.78180291566155
Smpd2	ENSMUSG00000019822	0.0434194723707708	0.130258417112312	0.120545895661628	0.180818843492441	0.5155648232968	0.5155648232968
Pcbd1	ENSMUSG00000020098	0.147458757705095	0.221188136557642	0.0109864933352154	0.0329594800056461	0.776919261684345	0.776919261684345
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Nme2	ENSMUSG00000020857	0.0240240261603446	0.0720720784810337	0.63250023504486	0.84992097596507	0.84992097596507	0.84992097596507
Fut8	ENSMUSG00000021065	0.252920381501207	0.588364690595531	0.926550375688041	0.926550375688041	0.392243127063687	0.588364690595531
Pfkp	ENSMUSG00000021196	0.643359829732651	0.643359829732651	0.00719286546902974	0.0215785964070892	0.144820068500793	0.21723010275119
Gcnt2	ENSMUSG00000021360	0.7802108304765	0.853372965654504	0.138826917499775	0.416480752499324	0.853372965654504	0.853372965654504
Sptlc1	ENSMUSG00000021468	0.926550375688041	0.926550375688041	0.577259514257969	0.926550375688041	0.640355507848752	0.926550375688041
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Cryl1	ENSMUSG00000021947	0.148772260628989	0.446316781886968	0.513665062682276	0.770497594023414	0.926658283600152	0.926658283600152
Esd	ENSMUSG00000021996	0.300095920620218	0.450143880930327	0.252545530864481	0.450143880930327	0.853694531487825	0.853694531487825
Tgds	ENSMUSG00000022130	0.708745765211584	0.78148726569172	0.255901190956604	0.767703572869812	0.78148726569172	0.78148726569172
Dad1	ENSMUSG00000022174	0.576973746230334	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Cmbl	ENSMUSG00000022235	0.144820068500793	0.21723010275119	0.0300013992894481	0.0900041978683442	1	1
Gpaa1	ENSMUSG00000022561	0.0334587898203824	0.100376369461147	0.346527959006435	0.519791938509652	0.642366752097095	0.642366752097095
Tsta3	ENSMUSG00000022570	0.254414773803597	0.763244321410791	0.5155648232968	0.7733472349452	1	1
Pycrl	ENSMUSG00000022571	0.11810342389482	0.354310271684459	0.454600801949285	0.681901202923927	0.710001140920767	0.710001140920767
Miox	ENSMUSG00000022613	0.776919261684345	0.776919261684345	0.776919261684345	0.776919261684345	0.169004966573789	0.507014899721366
Nit2	ENSMUSG00000022751	0.0241933715424143	0.0725801146272428	0.148772260628989	0.223158390943484	1	1
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Pigp	ENSMUSG00000022940	0.256271555563966	0.384407333345949	0.450094379653806	0.450094379653806	0.254787123615605	0.384407333345949
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Synj1	ENSMUSG00000022973	0.0449262652924809	0.134778795877443	0.120850531362929	0.181275797044394	0.711650020253571	0.711650020253571
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Rpp14	ENSMUSG00000023156	0.174692232033629	0.524076696100887	0.391498225369152	0.587247338053727	0.633039971999413	0.633039971999413
Glo1	ENSMUSG00000024026	0.701310685803632	0.703556284613037	0.703556284613037	0.703556284613037	0.44726599573338	0.703556284613037
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Pigf	ENSMUSG00000024145	0.640861491578951	0.708745765211584	0.249907451332337	0.708745765211584	0.708745765211584	0.708745765211584
Fads2	ENSMUSG00000024665	0.853694531487825	0.853694531487825	0.344663224299303	0.853694531487825	0.782117202022501	0.853694531487825
Pip5k1b	ENSMUSG00000024867	0.400265374208515	0.600398061312773	0.255530331334266	0.600398061312773	0.853480389728993	0.853480389728993
Papss2	ENSMUSG00000024899	0.216214347033995	0.648643041101984	0.853372965654504	1	1	1
Cyp26a1	ENSMUSG00000024987	0.5693351967396	0.576687400573867	0.576687400573867	0.576687400573867	0.142830916318171	0.428492748954512
Gsto2	ENSMUSG00000025069	0.254041925545275	0.762125776635824	0.779726369441083	0.779726369441083	0.514617706526787	0.77192655979018
Sirt7	ENSMUSG00000025138	0.0116356061791785	0.0349068185375355	0.180293335960318	0.270440003940477	0.700627001620904	0.700627001620904
Cbr2	ENSMUSG00000025150	0.297095062262362	0.449023590082343	0.299349060054895	0.449023590082343	0.711650020253571	0.711650020253571
Hsd17b10	ENSMUSG00000025260	0.926333123228344	0.926333123228344	0.925444427431699	0.926333123228344	0.57466664340579	0.926333123228344
Sat1	ENSMUSG00000025283	0.926003599371282	0.926003599371282	0.451840588205062	0.677760882307593	0.450794830295118	0.677760882307593
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Taldo1	ENSMUSG00000025503	0.575824878403157	0.575824878403157	0.348008842235184	0.575824878403157	0.45596561163947	0.575824878403157
Tk1	ENSMUSG00000025574	0.0236697127745139	0.0710091383235416	0.926604389137101	0.926604389137101	0.926496242814507	0.926604389137101
Pde8a	ENSMUSG00000025584	0.399548817627028	0.711034989117171	0.711034989117171	0.711034989117171	0.643359829732651	0.711034989117171
Gsta3	ENSMUSG00000025934	0.781170242226513	0.781170242226513	0.347639524025037	0.781170242226513	0.710208797518812	0.781170242226513
Pycr2	ENSMUSG00000026520	0.00159435459956481	0.00478306379869443	0.0115535350288052	0.0173303025432078	0.78148726569172	0.78148726569172
Pigc	ENSMUSG00000026698	0.925387810388836	0.925387810388836	0.088340911853132	0.265022735559396	0.924814453025535	0.925387810388836
Dpm2	ENSMUSG00000026810	0.0230207752632622	0.0345311628948933	0.00400309634280189	0.0120092890284057	0.575536202757516	0.575536202757516
Dnmt3b	ENSMUSG00000027478	0.0114717288267218	0.0233230904825838	0.781960228679124	0.781960228679124	0.0155487269883892	0.0233230904825838
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Cyp2u1	ENSMUSG00000027983	0.214764523938594	0.644293571815781	0.566593564630738	0.778253541606068	0.778253541606068	0.778253541606068
Uox	ENSMUSG00000028186	0.853694531487825	0.853694531487825	0.178901132102685	0.268351698154027	0.0588232673880149	0.176469802164045
Coq3	ENSMUSG00000028247	0.252545530864481	0.588364690595531	0.710208797518812	0.710208797518812	0.392243127063687	0.588364690595531
Ugcg	ENSMUSG00000028381	0.0761127945805735	0.22833838374172	0.214764523938594	0.299349060054895	0.299349060054895	0.299349060054895
Nudt2	ENSMUSG00000028443	0.120850531362929	0.362551594088788	0.577829325134931	0.853801250889739	0.853801250889739	0.853801250889739
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Gale	ENSMUSG00000028671	0.0588232673880149	0.176469802164045	1	1	0.852832278580641	1
Urod	ENSMUSG00000028684	0.643359829732651	0.779888212132595	0.148115998140416	0.444347994421247	0.779888212132595	0.779888212132595
Mecr	ENSMUSG00000028910	0.0743693776059065	0.0936419271039908	0.091411676944639	0.0936419271039908	0.0936419271039908	0.0936419271039908
Nmnat1	ENSMUSG00000028992	0.179945789077372	0.270960820366545	1	1	0.18064054691103	0.270960820366545
Fam213b	ENSMUSG00000029059	0.216214347033995	0.324321520550992	0.174692232033629	0.324321520550992	0.514300775319626	0.514300775319626
Ugdh	ENSMUSG00000029201	0.00755778364492931	0.0226733509347879	0.246861959455465	0.370292939183197	0.454942951775342	0.454942951775342
Nudt9	ENSMUSG00000029310	0.641867098978198	0.852832278580641	0.852832278580641	0.852832278580641	0.447621891168214	0.852832278580641
Coq2	ENSMUSG00000029319	0.399548817627028	0.599323226440542	0.254787123615605	0.599323226440542	0.852940894477647	0.852940894477647
Sirt4	ENSMUSG00000029524	0.454942951775342	0.578396848531894	0.578396848531894	0.578396848531894	0.577259514257969	0.578396848531894
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ahcyl2	ENSMUSG00000029772	0.0315593554855452	0.0946780664566357	0.297095062262362	0.347639524025037	0.347639524025037	0.347639524025037
Nt5c3	ENSMUSG00000029780	0.852504981253341	0.853372965654504	0.214037080764326	0.642111242292977	0.853372965654504	0.853372965654504
Mtmr14	ENSMUSG00000030269	0.044737329683373	0.0671059945250596	0.0113089139751576	0.0339267419254727	0.204800057477424	0.204800057477424
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Oat	ENSMUSG00000030934	0.638824656785692	0.78148726569172	0.252545530864481	0.757636592593443	0.78148726569172	0.78148726569172
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ebp	ENSMUSG00000031168	0.509798138101151	0.707899741868332	0.707899741868332	0.707899741868332	0.0964252305385472	0.289275691615642
Ctps2	ENSMUSG00000031360	0.180293335960318	0.540880007880955	0.926658283600152	0.926658283600152	0.78180291566155	0.926658283600152
Cbr4	ENSMUSG00000031641	0.346899083932133	0.926441990075769	0.926441990075769	0.926441990075769	0.778911768167544	0.926441990075769
Mtmr2	ENSMUSG00000031918	0.216214347033995	0.522566341862834	0.34837756124189	0.522566341862834	0.78180291566155	0.78180291566155
Pts	ENSMUSG00000032067	0.776919261684345	0.776919261684345	0.776919261684345	0.776919261684345	0.25141795904251	0.754253877127531
Elovl4	ENSMUSG00000032262	0.0586042534833405	0.175812760450021	0.781960228679124	0.781960228679124	0.399189600887034	0.598784401330551
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Gclc	ENSMUSG00000032350	0.0115535350288052	0.0346606050864156	0.115037265385284	0.172555898077926	0.455625354715449	0.455625354715449
Qars	ENSMUSG00000032604	0.926550375688041	0.926550375688041	0.121155015244363	0.363465045733089	0.926550375688041	0.926550375688041
Gstt2	ENSMUSG00000033318	0.144820068500794	0.382180685423408	0.254787123615605	0.382180685423408	0.575824878403157	0.575824878403157
Ptplad1	ENSMUSG00000033629	0.513665062682276	0.770497594023414	0.180293335960318	0.540880007880955	0.853801250889739	0.853801250889739
Atp6v1h	ENSMUSG00000033793	0.0548979200435555	0.164693760130667	0.161774914569557	0.242662371854336	0.346899083932133	0.346899083932133
Tmem5	ENSMUSG00000034620	0.0583853430099098	0.175156029029729	0.578396848531894	0.578396848531894	0.252920381501207	0.37938057225181
Nagk	ENSMUSG00000034744	0.00153425095635555	0.00460275286906664	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Hyal3	ENSMUSG00000036091	0.179249687218049	0.514934023620344	0.455625354715449	0.514934023620344	0.514934023620344	0.514934023620344
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Enpp1	ENSMUSG00000037370	0.399548817627028	0.599323226440542	0.393724994268831	0.599323226440542	0.642366752097095	0.642366752097095
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Alg1	ENSMUSG00000039427	0.120545895661628	0.180818843492441	0.00276975149305653	0.00830925447916959	0.299349060054895	0.299349060054895
Dcxr	ENSMUSG00000039450	0.179945789077372	0.269918683616058	0.0763619660358786	0.229085898107636	0.706616781330066	0.706616781330066
Ggt6	ENSMUSG00000040471	0.0113089139751576	0.0339267419254727	0.0947558980989551	0.142133847148433	0.711240436189781	0.711240436189781
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Bhmt2	ENSMUSG00000042118	0.293293089483362	0.879879268450085	0.926003599371282	0.926003599371282	0.701310685803632	0.926003599371282
Dctpp1	ENSMUSG00000042462	0.0168921052924601	0.0506763158773803	0.211844580334808	0.317766870502212	0.851061028660105	0.851061028660105
Dpm3	ENSMUSG00000042737	0.0969812105731562	0.290943631719469	0.399548817627028	0.599323226440542	0.92622377157404	0.92622377157404
Mgat2	ENSMUSG00000043998	0.255530331334266	0.576112968612194	0.514934023620345	0.576112968612194	0.576112968612194	0.576112968612194
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Mcat	ENSMUSG00000048755	0.000747579742686131	0.00224273922805839	0.0168921052924602	0.0253381579386902	0.711034989117171	0.711034989117171
Idnk	ENSMUSG00000050002	0.000844544805216504	0.00253363441564951	0.0953125666339398	0.14296884995091	0.398108175780842	0.398108175780842
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Suclg1	ENSMUSG00000052738	0.92622377157404	0.92622377157404	0.852175490580835	0.92622377157404	0.57466664340579	0.92622377157404
Hadhb	ENSMUSG00000059447	0.295581119060361	0.443371678590541	0.0217422311863571	0.0652266935590713	0.710208797518812	0.710208797518812
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Ipmk	ENSMUSG00000060733	0.0721303428592824	0.216391028577847	0.340887582990546	0.340887582990546	0.17750354896016	0.26625532344024
Ext1	ENSMUSG00000061731	0.120545895661628	0.361637686984883	0.346899083932133	0.520348625898199	0.852940894477647	0.852940894477647
Pgk1	ENSMUSG00000062070	0.118714930081337	0.200650219614881	0.163231646296655	0.200650219614881	0.200650219614881	0.200650219614881
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Rdh11	ENSMUSG00000066441	0.0958690133561599	0.28760704006848	0.9255572759333	0.9255572759333	0.638824656785692	0.9255572759333
Gmppb	ENSMUSG00000070284	0.0168921052924602	0.0506763158773805	0.399548817627028	0.455625354715449	0.455625354715449	0.455625354715449
Ugt2b36	ENSMUSG00000070704	0.576112968612194	0.853801250889739	0.711650020253571	0.853801250889739	0.853801250889739	0.853801250889739
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Nme3	ENSMUSG00000073435	0.17750354896016	0.353909908268917	0.235939938845945	0.353909908268917	0.638310022345193	0.638310022345193
Gm10639	ENSMUSG00000074179	0.00159435459956481	0.00478306379869442	0.711854160331342	1	1	1
Mgst2	ENSMUSG00000074604	0.567513221841557	0.63250023504486	0.63250023504486	0.63250023504486	0.146141353215796	0.438424059647387
Itpa	ENSMUSG00000074797	0.450794830295118	0.924872384323463	0.706616781330066	0.924872384323463	0.924872384323463	0.924872384323463
Gm2382	ENSMUSG00000079427	0.430127325243114	0.430127325243114	0.270898788519615	0.406348182779423	0.174692232033629	0.406348182779423

Download data as csv

Alzheimer disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Bid	ENSMUSG00000004446	0.299349060054895	0.449023590082343	0.92589277149125	0.92589277149125	0.253294730253594	0.449023590082343
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Hsd17b10	ENSMUSG00000025260	0.926333123228344	0.926333123228344	0.925444427431699	0.926333123228344	0.57466664340579	0.926333123228344
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Calml4	ENSMUSG00000032246	0.573498913947369	0.573498913947369	0.118714930081337	0.223158390943484	0.148772260628989	0.223158390943484
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Psenen	ENSMUSG00000036835	0.0231500557096833	0.06945016712905	0.0566379395854602	0.0849569093781904	0.399548817627028	0.399548817627028
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
9430023L20Rik	ENSMUSG00000037204	0.068655014038086	0.205965042114258	0.138156294413154	0.207234441619731	0.398108175780842	0.398108175780842
Klc3	ENSMUSG00000040714	0.119631084167592	0.358893252502775	0.256271555563966	0.384407333345949	0.853694531487825	0.853694531487825
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

Download data as csv

RNA polymerase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr3g	ENSMUSG00000035834	0.0753654386865988	0.226096316059796	0.299349060054895	0.449023590082343	0.708534948098331	0.708534948098331
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Diabetic cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Cox6c	ENSMUSG00000014313	0.710416009055326	0.710416009055326	0.208156293081417	0.62446887924425	0.576973746230334	0.710416009055326
Slc25a5	ENSMUSG00000016319	0.0964252305385471	0.120850531362929	0.0964252305385471	0.120850531362929	0.120850531362929	0.120850531362929
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Cox8b	ENSMUSG00000025488	0.781960228679124	0.781960228679124	0.643606811957488	0.781960228679124	0.514617706526787	0.781960228679124
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Cox7a2	ENSMUSG00000032330	0.400265374208515	0.600398061312773	0.0231500557096833	0.06945016712905	1	1
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox6b2	ENSMUSG00000051811	0.117185073436597	0.351555220309791	0.926550375688041	0.926550375688041	0.925217182211634	0.926550375688041
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

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Protein processing in endoplasmic reticulum

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ssr4	ENSMUSG00000002014	0.573498913947369	0.853480389728993	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993
Bcap31	ENSMUSG00000002015	0.772410589885492	0.924286968561133	0.924286968561133	0.924286968561133	0.338592117141989	0.924286968561133
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Dnajb1	ENSMUSG00000005483	0.254414773803597	0.682414427663012	0.92622377157404	0.92622377157404	0.454942951775342	0.682414427663012
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Ubxn6	ENSMUSG00000019578	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656	0.643853282854191	0.643853282854191
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Sar1a	ENSMUSG00000020088	0.146800541856249	0.440401625568746	0.777255087907932	0.9255572759333	0.9255572759333	0.9255572759333
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Dad1	ENSMUSG00000022174	0.576973746230334	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Syvn1	ENSMUSG00000024807	0.024062085667391	0.072186257002173	0.711650020253571	0.926441990075769	0.926441990075769	0.926441990075769
Pdia4	ENSMUSG00000025823	0.454942951775341	0.926658283600152	0.926658283600152	0.926658283600152	0.643853282854191	0.926658283600152
Tram1	ENSMUSG00000025935	0.146800541856249	0.440401625568746	0.782117202022501	0.782117202022501	0.7802108304765	0.782117202022501
Ubxn4	ENSMUSG00000026353	0.348008842235184	1	1	1	1	1
Dnajc1	ENSMUSG00000026740	0.0753654386865988	0.113048158029898	0.0575107614292586	0.113048158029898	0.642366752097095	0.642366752097095
Ube2j1	ENSMUSG00000028277	0.711240436189781	0.926658283600152	0.926658283600152	0.926658283600152	0.0166824765447319	0.0500474296341958
Dnaja1	ENSMUSG00000028410	0.0115535350288052	0.0346606050864156	0.120545895661628	0.180818843492441	0.853480389728993	0.853480389728993
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Calr4	ENSMUSG00000028558	0.346527959006435	0.670898993600072	0.447265995733381	0.670898993600072	0.926333123228344	0.926333123228344
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Os9	ENSMUSG00000040462	0.782117202022501	0.926550375688041	0.853480389728993	0.926550375688041	0.926550375688041	0.926550375688041
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Sec61b	ENSMUSG00000053317	0.11993617140438	0.220200812784373	0.146800541856249	0.220200812784373	0.853049270252403	0.853049270252403
Hspbp1	ENSMUSG00000063802	0.0171027900598199	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.294820734456232	0.294820734456232
Svip	ENSMUSG00000074093	0.926658283600152	1	0.214764523938594	0.644293571815781	1	1
Sec61g	ENSMUSG00000078974	0.399548817627028	0.599323226440542	0.148115998140416	0.444347994421247	0.782117202022501	0.782117202022501

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Proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Retrograde endocannabinoid signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufa11	ENSMUSG00000002379	0.0367873939579747	0.110362181873924	0.136812262667828	0.205218394001742	0.92589277149125	0.92589277149125
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Gabrb2	ENSMUSG00000007653	0.0432318933800775	0.0432318933800775	0.0221230395928305	0.0331845593892457	0.010906560635693	0.032719681907079
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Ndufs4	ENSMUSG00000021764	0.544759382073508	0.544759382073508	0.0497293992720784	0.149188197816235	0.255901190956604	0.383851786434906
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Kcnj3	ENSMUSG00000026824	0.21549027811633	0.64647083434899	0.711650020253571	0.711650020253571	0.710001140920767	0.711650020253571
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Gng12	ENSMUSG00000036402	0.853372965654504	0.853372965654504	0.0761127945805735	0.228338383741721	0.398829756175299	0.598244634262948
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Gngt2	ENSMUSG00000038811	0.178901132102685	0.536703396308054	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

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Spliceosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Ccdc12	ENSMUSG00000019659	0.000844544805216502	0.00253363441564951	0.0419238354397912	0.0628857531596868	0.711854160331342	0.711854160331342
Prpf40b	ENSMUSG00000023007	0.254414773803597	0.442231101684348	0.572616808177226	0.572616808177226	0.294820734456232	0.442231101684348
Ppil1	ENSMUSG00000024007	0.0116356061791785	0.0174534092687677	0.0113089139751576	0.0174534092687677	0.78180291566155	0.78180291566155
Srsf7	ENSMUSG00000024097	0.578396848531894	0.926658283600152	0.926658283600152	0.926658283600152	0.710001140920767	0.926658283600152
Dhx16	ENSMUSG00000024422	0.778911768167544	0.778911768167544	0.058823267388015	0.176469802164045	0.120850531362929	0.181275797044394
Tcerg1	ENSMUSG00000024498	0.852832278580641	0.852832278580641	0.0763619660358785	0.144637845807821	0.0964252305385473	0.144637845807821
Ctnnbl1	ENSMUSG00000027649	0.577829325134931	0.640861491578951	0.253294730253594	0.640861491578951	0.640861491578951	0.640861491578951
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Hnrnpu	ENSMUSG00000039630	0.395196379647461	0.454600801949285	0.297095062262362	0.454600801949285	0.454600801949285	0.454600801949285
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Phf5a	ENSMUSG00000061360	0.11595859961889	0.173937899428335	0.0743693776059065	0.173937899428335	0.640355507848752	0.640355507848752
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Lsm5	ENSMUSG00000091625	0.11993617140438	0.359808514213139	0.347639524025037	0.521459286037555	0.782117202022501	0.782117202022501

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SNARE interactions in vesicular transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Use1	ENSMUSG00000002395	0.345037391052887	0.772401035430517	1	1	0.514934023620345	0.772401035430517
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Stx8	ENSMUSG00000020903	0.774871910813158	0.925331064166297	0.0575107614292586	0.172532284287776	0.925331064166297	0.925331064166297
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Vamp4	ENSMUSG00000026696	0.0434194723707709	0.130258417112313	0.211844580334808	0.317766870502212	0.455625354715449	0.455625354715449
Vamp3	ENSMUSG00000028955	0.850721744111585	0.852940894477647	0.852940894477647	0.852940894477647	0.711034989117171	0.852940894477647
Stx18	ENSMUSG00000029125	0.0588232673880149	0.0882349010820223	0.0579478375430677	0.0882349010820223	0.577829325134931	0.577829325134931
Vamp8	ENSMUSG00000050732	0.206668954082487	0.31000343112373	0.167569692867573	0.31000343112373	0.514934023620345	0.514934023620345

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Nucleotide excision repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Rpa2	ENSMUSG00000028884	4.47582010022109e-05	0.000134274603006633	0.633039971999413	0.707899741868332	0.707899741868332	0.707899741868332
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058

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Translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Mrps24	ENSMUSG00000020477	0.214037080764326	0.321055621146488	0.023800255149993	0.0714007654499789	0.576973746230334	0.576973746230334
Eral1	ENSMUSG00000020832	0.0243249029874197	0.0729747089622591	0.0583853430099098	0.0875780145148646	0.0969812105731562	0.0969812105731562
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Mrpl39	ENSMUSG00000022889	0.348008842235184	0.522566341862834	0.926550375688041	0.926550375688041	0.34837756124189	0.522566341862834
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Mrpl53	ENSMUSG00000030037	0.211844580334808	0.323235417174495	0.21549027811633	0.323235417174495	0.447265995733381	0.447265995733381
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Srp72	ENSMUSG00000036323	0.148772260628989	0.223158390943483	0.0331400397096515	0.0994201191289544	0.926550375688041	0.926550375688041
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Eef1a1	ENSMUSG00000037742	0.0761127945805735	0.228338383741721	0.451840588205062	0.575824878403157	0.575824878403157	0.575824878403157
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Mrps28	ENSMUSG00000040269	0.291756209988535	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Chchd1	ENSMUSG00000063787	0.779888212132595	0.779888212132595	0.570836132666921	0.779888212132595	0.395196379647461	0.779888212132595
Aurkaip1	ENSMUSG00000065990	0.11595859961889	0.347875798856669	0.710001140920767	0.78180291566155	0.78180291566155	0.78180291566155
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Dap3	ENSMUSG00000068921	0.11595859961889	0.347875798856669	0.450444934184774	0.452880492349546	0.452880492349546	0.452880492349546
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Metabolism of RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Nob1	ENSMUSG00000003848	0.7802108304765	0.7802108304765	0.711854160331342	0.7802108304765	0.573791743469336	0.7802108304765
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Emg1	ENSMUSG00000004268	0.0953125666339397	0.285937699901819	0.246861959455465	0.370292939183197	0.563799176258241	0.563799176258241
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Senp3	ENSMUSG00000005204	0.252545530864481	0.378818296296722	0.0588232673880149	0.176469802164045	0.926550375688041	0.926550375688041
Ddx39	ENSMUSG00000005481	0.0236697127745139	0.0710091383235416	0.640861491578951	0.640861491578951	0.640355507848752	0.640861491578951
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Zmat5	ENSMUSG00000009076	0.00695468356472021	0.0104320253470803	0.00695468356472022	0.0104320253470803	0.513665062682276	0.513665062682276
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Fcf1	ENSMUSG00000021243	0.338976281569376	0.852175490580835	0.710208797518812	0.852175490580835	0.852175490580835	0.852175490580835
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Ppil1	ENSMUSG00000024007	0.0116356061791785	0.0174534092687677	0.0113089139751576	0.0174534092687677	0.78180291566155	0.78180291566155
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Dhx16	ENSMUSG00000024422	0.778911768167544	0.778911768167544	0.058823267388015	0.176469802164045	0.120850531362929	0.181275797044394
Rpp21	ENSMUSG00000024446	0.455625354715449	0.853694531487825	0.853694531487825	0.853694531487825	0.782117202022501	0.853694531487825
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rcl1	ENSMUSG00000024785	0.0113089139751576	0.0339267419254727	0.706831781264722	0.780851835278818	0.780851835278818	0.780851835278818
Exosc7	ENSMUSG00000025785	0.118409250205154	0.355227750615461	0.456305241393103	0.456305241393103	0.348008842235184	0.456305241393103
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Ppil3	ENSMUSG00000026035	0.926658283600152	0.926658283600152	0.576973746230334	0.926658283600152	0.92622377157404	0.926658283600152
Cwc22	ENSMUSG00000027014	0.450094379653806	0.511097249598474	0.395928178642446	0.511097249598474	0.511097249598474	0.511097249598474
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Ctnnbl1	ENSMUSG00000027649	0.577829325134931	0.640861491578951	0.253294730253594	0.640861491578951	0.640861491578951	0.640861491578951
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Bms1	ENSMUSG00000030138	0.398108175780842	0.597162263671263	0.178901132102685	0.536703396308054	0.643359829732651	0.643359829732651
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Imp3	ENSMUSG00000032288	0.148115998140416	0.222173997210623	0.0548979200435556	0.164693760130667	0.297095062262363	0.297095062262363
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Dis3	ENSMUSG00000033166	0.45596561163947	0.45596561163947	0.120850531362929	0.362551594088788	0.453570536021945	0.45596561163947
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cnot3	ENSMUSG00000035632	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017
Nop14	ENSMUSG00000036693	0.400265374208516	0.926003599371281	0.7802108304765	0.926003599371281	0.926003599371281	0.926003599371281
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Cnot4	ENSMUSG00000038784	0.144820068500793	0.43446020550238	0.300095920620218	0.450143880930327	0.575824878403157	0.575824878403157
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Hnrnpu	ENSMUSG00000039630	0.395196379647461	0.454600801949285	0.297095062262362	0.454600801949285	0.454600801949285	0.454600801949285
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Snrnp25	ENSMUSG00000040767	0.253294730253594	0.345410946355104	0.119631084167592	0.345410946355104	0.345410946355104	0.345410946355104
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gemin2	ENSMUSG00000060121	0.180293335960318	0.383295497001398	0.450444934184774	0.450444934184774	0.255530331334266	0.383295497001398
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Phf5a	ENSMUSG00000061360	0.11595859961889	0.173937899428335	0.0743693776059065	0.173937899428335	0.640355507848752	0.640355507848752
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rpp25	ENSMUSG00000062309	0.926550375688041	0.926550375688041	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Lsm5	ENSMUSG00000091625	0.11993617140438	0.359808514213139	0.347639524025037	0.521459286037555	0.782117202022501	0.782117202022501
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

SRP-dependent cotranslational protein targeting to membrane

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Srp72	ENSMUSG00000036323	0.148772260628989	0.223158390943483	0.0331400397096515	0.0994201191289544	0.926550375688041	0.926550375688041
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Formation of a pool of free 40S subunits

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

L13a-mediated translational silencing of Ceruloplasmin expression

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

GTP hydrolysis and joining of the 60S ribosomal subunit

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Cap-dependent Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Eukaryotic Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

rRNA processing in the nucleus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Nob1	ENSMUSG00000003848	0.7802108304765	0.7802108304765	0.711854160331342	0.7802108304765	0.573791743469336	0.7802108304765
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Emg1	ENSMUSG00000004268	0.0953125666339397	0.285937699901819	0.246861959455465	0.370292939183197	0.563799176258241	0.563799176258241
Senp3	ENSMUSG00000005204	0.252545530864481	0.378818296296722	0.0588232673880149	0.176469802164045	0.926550375688041	0.926550375688041
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Fcf1	ENSMUSG00000021243	0.338976281569376	0.852175490580835	0.710208797518812	0.852175490580835	0.852175490580835	0.852175490580835
Rpp21	ENSMUSG00000024446	0.455625354715449	0.853694531487825	0.853694531487825	0.853694531487825	0.782117202022501	0.853694531487825
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rcl1	ENSMUSG00000024785	0.0113089139751576	0.0339267419254727	0.706831781264722	0.780851835278818	0.780851835278818	0.780851835278818
Exosc7	ENSMUSG00000025785	0.118409250205154	0.355227750615461	0.456305241393103	0.456305241393103	0.348008842235184	0.456305241393103
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Bms1	ENSMUSG00000030138	0.398108175780842	0.597162263671263	0.178901132102685	0.536703396308054	0.643359829732651	0.643359829732651
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Imp3	ENSMUSG00000032288	0.148115998140416	0.222173997210623	0.0548979200435556	0.164693760130667	0.297095062262363	0.297095062262363
Dis3	ENSMUSG00000033166	0.45596561163947	0.45596561163947	0.120850531362929	0.362551594088788	0.453570536021945	0.45596561163947
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Nop14	ENSMUSG00000036693	0.400265374208516	0.926003599371281	0.7802108304765	0.926003599371281	0.926003599371281	0.926003599371281
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rpp25	ENSMUSG00000062309	0.926550375688041	0.926550375688041	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Major pathway of rRNA processing in the nucleolus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Nob1	ENSMUSG00000003848	0.7802108304765	0.7802108304765	0.711854160331342	0.7802108304765	0.573791743469336	0.7802108304765
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Emg1	ENSMUSG00000004268	0.0953125666339397	0.285937699901819	0.246861959455465	0.370292939183197	0.563799176258241	0.563799176258241
Senp3	ENSMUSG00000005204	0.252545530864481	0.378818296296722	0.0588232673880149	0.176469802164045	0.926550375688041	0.926550375688041
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Fcf1	ENSMUSG00000021243	0.338976281569376	0.852175490580835	0.710208797518812	0.852175490580835	0.852175490580835	0.852175490580835
Rpp21	ENSMUSG00000024446	0.455625354715449	0.853694531487825	0.853694531487825	0.853694531487825	0.782117202022501	0.853694531487825
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rcl1	ENSMUSG00000024785	0.0113089139751576	0.0339267419254727	0.706831781264722	0.780851835278818	0.780851835278818	0.780851835278818
Exosc7	ENSMUSG00000025785	0.118409250205154	0.355227750615461	0.456305241393103	0.456305241393103	0.348008842235184	0.456305241393103
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Bms1	ENSMUSG00000030138	0.398108175780842	0.597162263671263	0.178901132102685	0.536703396308054	0.643359829732651	0.643359829732651
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Imp3	ENSMUSG00000032288	0.148115998140416	0.222173997210623	0.0548979200435556	0.164693760130667	0.297095062262363	0.297095062262363
Dis3	ENSMUSG00000033166	0.45596561163947	0.45596561163947	0.120850531362929	0.362551594088788	0.453570536021945	0.45596561163947
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Nop14	ENSMUSG00000036693	0.400265374208516	0.926003599371281	0.7802108304765	0.926003599371281	0.926003599371281	0.926003599371281
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rpp25	ENSMUSG00000062309	0.926550375688041	0.926550375688041	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

rRNA processing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Nob1	ENSMUSG00000003848	0.7802108304765	0.7802108304765	0.711854160331342	0.7802108304765	0.573791743469336	0.7802108304765
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Emg1	ENSMUSG00000004268	0.0953125666339397	0.285937699901819	0.246861959455465	0.370292939183197	0.563799176258241	0.563799176258241
Senp3	ENSMUSG00000005204	0.252545530864481	0.378818296296722	0.0588232673880149	0.176469802164045	0.926550375688041	0.926550375688041
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Fcf1	ENSMUSG00000021243	0.338976281569376	0.852175490580835	0.710208797518812	0.852175490580835	0.852175490580835	0.852175490580835
Rpp21	ENSMUSG00000024446	0.455625354715449	0.853694531487825	0.853694531487825	0.853694531487825	0.782117202022501	0.853694531487825
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rcl1	ENSMUSG00000024785	0.0113089139751576	0.0339267419254727	0.706831781264722	0.780851835278818	0.780851835278818	0.780851835278818
Exosc7	ENSMUSG00000025785	0.118409250205154	0.355227750615461	0.456305241393103	0.456305241393103	0.348008842235184	0.456305241393103
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Bms1	ENSMUSG00000030138	0.398108175780842	0.597162263671263	0.178901132102685	0.536703396308054	0.643359829732651	0.643359829732651
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Imp3	ENSMUSG00000032288	0.148115998140416	0.222173997210623	0.0548979200435556	0.164693760130667	0.297095062262363	0.297095062262363
Dis3	ENSMUSG00000033166	0.45596561163947	0.45596561163947	0.120850531362929	0.362551594088788	0.453570536021945	0.45596561163947
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Nop14	ENSMUSG00000036693	0.400265374208516	0.926003599371281	0.7802108304765	0.926003599371281	0.926003599371281	0.926003599371281
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rpp25	ENSMUSG00000062309	0.926550375688041	0.926550375688041	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

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Nonsense-Mediated Decay (NMD)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

Download data as csv

Metabolism of proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cct3	ENSMUSG00000001416	0.178901132102685	0.507830090867449	0.400265374208515	0.507830090867449	0.507830090867449	0.507830090867449
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Fbxo7	ENSMUSG00000001786	0.173632433887832	0.367990297261757	0.245326864841171	0.367990297261757	0.92622377157404	0.92622377157404
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Rpl8	ENSMUSG00000003970	0.0328221470541517	0.098466441162455	0.177153312234059	0.265729968351089	0.640861491578951	0.640861491578951
Etfb	ENSMUSG00000004610	0.058823267388015	0.0882349010820225	0.0168921052924602	0.0506763158773805	0.567513221841557	0.567513221841557
Rab11a	ENSMUSG00000004771	0.147458757705094	0.442376273115283	0.455625354715448	0.455625354715448	0.346527959006434	0.455625354715448
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gata6	ENSMUSG00000005836	0.643359829732651	1	1	1	0.926658283600152	1
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Cct4	ENSMUSG00000007739	1	1	0.577259514257969	1	0.711034989117171	1
Rplp1	ENSMUSG00000007892	0.0964252305385472	0.289275691615642	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Fbxw9	ENSMUSG00000008167	0.509798138101151	0.764697207151727	0.0763619660358786	0.229085898107636	0.7802108304765	0.7802108304765
Rab25	ENSMUSG00000008601	0.513665062682276	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Nedd8	ENSMUSG00000010376	0.0852666932085725	0.255800079625717	0.297095062262362	0.445642593393544	0.643359829732651	0.643359829732651
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Rab5a	ENSMUSG00000017831	0.256271555563966	0.299349060054895	0.255901190956604	0.299349060054895	0.299349060054895	0.299349060054895
B4galt5	ENSMUSG00000017929	0.78148726569172	0.78180291566155	0.638310022345193	0.78180291566155	0.78180291566155	0.78180291566155
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Cog1	ENSMUSG00000018661	0.780851835278817	1	1	1	0.514934023620344	1
Rab5c	ENSMUSG00000019173	0.398108175780842	1	1	1	0.926658283600152	1
Fkbp8	ENSMUSG00000019428	0.0334587898203823	0.100376369461147	0.216214347033995	0.324321520550992	0.926658283600152	0.926658283600152
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Socs2	ENSMUSG00000020027	0.00264953297731414	0.00794859893194243	0.642864324224729	0.642864324224729	0.450794830295118	0.642864324224729
Sumo3	ENSMUSG00000020265	0.398108175780842	0.398108175780842	0.246861959455465	0.370292939183197	0.246861959455465	0.370292939183197
Fstl3	ENSMUSG00000020325	0.7802108304765	0.7802108304765	0.454942951775341	0.682414427663012	0.297848640636702	0.682414427663012
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Mrps24	ENSMUSG00000020477	0.214037080764326	0.321055621146488	0.023800255149993	0.0714007654499789	0.576973746230334	0.576973746230334
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Eral1	ENSMUSG00000020832	0.0243249029874197	0.0729747089622591	0.0583853430099098	0.0875780145148646	0.0969812105731562	0.0969812105731562
Fut8	ENSMUSG00000021065	0.252920381501207	0.588364690595531	0.926550375688041	0.926550375688041	0.392243127063687	0.588364690595531
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Ripk1	ENSMUSG00000021408	0.577829325134931	0.782117202022501	0.044737329683373	0.134211989050119	0.782117202022501	0.782117202022501
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Dph3	ENSMUSG00000021905	0.711240436189781	0.853801250889739	0.853801250889739	0.853801250889739	0.710001140920767	0.853801250889739
Spcs1	ENSMUSG00000021917	0.849805525376199	0.849805525376199	0.633039971999413	0.849805525376199	0.450444934184774	0.849805525376199
N6amt2	ENSMUSG00000021951	0.345037391052887	0.577829325134931	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Hdac7	ENSMUSG00000022475	0.072378961026407	0.217136883079221	0.450794830295118	0.450794830295118	0.337435786255284	0.450794830295118
Gpaa1	ENSMUSG00000022561	0.0334587898203824	0.100376369461147	0.346527959006435	0.519791938509652	0.642366752097095	0.642366752097095
Tsta3	ENSMUSG00000022570	0.254414773803597	0.763244321410791	0.5155648232968	0.7733472349452	1	1
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mfi2	ENSMUSG00000022780	0.119020462826154	0.178530694239232	0.00472596298562399	0.014177888956872	0.250663719290221	0.250663719290221
Usp25	ENSMUSG00000022867	0.578113371816017	0.853801250889739	0.300095920620218	0.853801250889739	0.853801250889739	0.853801250889739
Kng1	ENSMUSG00000022875	0.710001140920767	0.710001140920767	0.120241108790035	0.360723326370104	0.298974794311434	0.448462191467151
Mrpl39	ENSMUSG00000022889	0.348008842235184	0.522566341862834	0.926550375688041	0.926550375688041	0.34837756124189	0.522566341862834
Pigp	ENSMUSG00000022940	0.256271555563966	0.384407333345949	0.450094379653806	0.450094379653806	0.254787123615605	0.384407333345949
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Pigf	ENSMUSG00000024145	0.640861491578951	0.708745765211584	0.249907451332337	0.708745765211584	0.708745765211584	0.708745765211584
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Wac	ENSMUSG00000024283	0.119631084167592	0.324321520550992	0.216214347033995	0.324321520550992	0.514934023620344	0.514934023620344
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Gbf1	ENSMUSG00000025224	0.146141353215796	0.219212029823694	0.0936419271039908	0.219212029823694	1	1
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Rpl14	ENSMUSG00000025794	0.0592616003460513	0.177784801038154	0.178901132102685	0.268351698154027	0.924987846321933	0.924987846321933
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Pigc	ENSMUSG00000026698	0.925387810388836	0.925387810388836	0.088340911853132	0.265022735559396	0.924814453025535	0.925387810388836
Dpm2	ENSMUSG00000026810	0.0230207752632622	0.0345311628948933	0.00400309634280189	0.0120092890284057	0.575536202757516	0.575536202757516
Ifih1	ENSMUSG00000026896	0.778911768167544	0.778911768167544	0.00477055016690543	0.0143116505007163	0.709375484777034	0.778911768167544
Commd9	ENSMUSG00000027163	0.213307944885796	0.639923834657388	0.455625354715448	0.683438032073173	0.92622377157404	0.92622377157404
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Dnmt3b	ENSMUSG00000027478	0.0114717288267218	0.0233230904825838	0.781960228679124	0.781960228679124	0.0155487269883892	0.0233230904825838
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Ptp4a2	ENSMUSG00000028788	0.711650020253571	0.926441990075769	0.398829756175299	0.926441990075769	0.926441990075769	0.926441990075769
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Rpl22	ENSMUSG00000028936	0.578113371816017	0.853049270252403	0.853049270252403	0.853049270252403	0.57466664340579	0.853049270252403
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Cct7	ENSMUSG00000030007	0.0592616003460512	0.177784801038154	0.18064054691103	0.270960820366546	0.852832278580641	0.852832278580641
Mrpl53	ENSMUSG00000030037	0.211844580334808	0.323235417174495	0.21549027811633	0.323235417174495	0.447265995733381	0.447265995733381
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Fbxo17	ENSMUSG00000030598	0.0805126803503835	0.120769020525575	0.0239310464924689	0.0717931394774068	0.635966700067775	0.635966700067775
Rab6a	ENSMUSG00000030704	0.0097403746490101	0.0292211239470303	0.091411676944639	0.137117515416958	0.92622377157404	0.92622377157404
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Atp6ap2	ENSMUSG00000031007	0.0958690133561599	0.28760704006848	1	1	0.397384062266614	0.596076093399921
Rab39b	ENSMUSG00000031202	0.712057867818062	0.853801250889739	0.454600801949285	0.853801250889739	0.853801250889739	0.853801250889739
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Asb11	ENSMUSG00000031382	1	1	0.400265374208515	0.865460619345501	0.576973746230334	0.865460619345501
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Arcn1	ENSMUSG00000032096	0.00755778364492933	0.011336675467394	0.00743512899358789	0.011336675467394	0.399548817627028	0.399548817627028
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Commd4	ENSMUSG00000032299	0.148115998140415	0.444347994421246	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781
Ube2q2	ENSMUSG00000032307	0.398108175780842	0.770497594023414	0.853372965654504	0.853372965654504	0.513665062682276	0.770497594023414
Usp3	ENSMUSG00000032376	0.0761127945805735	0.145471815859734	0.0969812105731561	0.145471815859734	0.399548817627028	0.399548817627028
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Tulp4	ENSMUSG00000034377	0.093084640707941	0.21723010275119	0.144820068500793	0.21723010275119	0.513665062682276	0.513665062682276
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Nagk	ENSMUSG00000034744	0.00153425095635555	0.00460275286906664	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Srp72	ENSMUSG00000036323	0.148772260628989	0.223158390943483	0.0331400397096515	0.0994201191289544	0.926550375688041	0.926550375688041
Gng12	ENSMUSG00000036402	0.853372965654504	0.853372965654504	0.0761127945805735	0.228338383741721	0.398829756175299	0.598244634262948
Exoc1	ENSMUSG00000036435	0.0441715176243983	0.132514552873195	0.578113371816017	0.578113371816017	0.299349060054895	0.449023590082343
Commd2	ENSMUSG00000036513	0.0763619660358786	0.114542949053818	0.0583853430099097	0.114542949053818	0.514934023620345	0.514934023620345
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Eef1a1	ENSMUSG00000037742	0.0761127945805735	0.228338383741721	0.451840588205062	0.575824878403157	0.575824878403157	0.575824878403157
Gngt2	ENSMUSG00000038811	0.178901132102685	0.536703396308054	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Nrn1	ENSMUSG00000039114	0.032663525449452	0.0979905763483559	0.643112334413352	0.643112334413352	0.455625354715449	0.643112334413352
Rpl22l1	ENSMUSG00000039221	0.120545895661628	0.180818843492441	0.11993617140438	0.180818843492441	0.926550375688041	0.926550375688041
Alg1	ENSMUSG00000039427	0.120545895661628	0.180818843492441	0.00276975149305653	0.00830925447916959	0.299349060054895	0.299349060054895
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Mrps28	ENSMUSG00000040269	0.291756209988535	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Otud3	ENSMUSG00000041161	0.34837756124189	0.593892267963669	0.711854160331342	0.711854160331342	0.395928178642446	0.593892267963669
Rpl37	ENSMUSG00000041841	0.514934023620345	0.852065168704833	0.852065168704833	0.852065168704833	0.708323672944427	0.852065168704833
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Commd10	ENSMUSG00000042705	0.00283103937188883	0.00849311811566649	0.344663224299303	0.516994836448954	0.853801250889739	0.853801250889739
Dpm3	ENSMUSG00000042737	0.0969812105731562	0.290943631719469	0.399548817627028	0.599323226440542	0.92622377157404	0.92622377157404
Rpl7	ENSMUSG00000043716	0.926550375688041	0.926550375688041	0.92589277149125	0.926550375688041	0.780851835278818	0.926550375688041
Mgat2	ENSMUSG00000043998	0.255530331334266	0.576112968612194	0.514934023620345	0.576112968612194	0.576112968612194	0.576112968612194
Nrn1l	ENSMUSG00000044287	0.392614583064079	0.588921874596118	0.706185359872137	0.706185359872137	0.253668577981715	0.588921874596118
Rpl37a	ENSMUSG00000046330	0.0947558980989551	0.284267694296865	0.513026869856283	0.769540304784424	0.853480389728993	0.853480389728993
B3gntl1	ENSMUSG00000046605	0.0243249029874197	0.0729747089622591	0.578113371816017	0.578113371816017	0.399548817627028	0.578113371816017
Rpl9	ENSMUSG00000047215	0.044737329683373	0.134211989050119	0.146141353215796	0.219212029823693	0.78180291566155	0.78180291566155
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Usp14	ENSMUSG00000047879	0.34837756124189	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Fbxl13	ENSMUSG00000048520	0.711240436189781	0.711240436189781	0.514934023620345	0.711240436189781	0.341647690705446	0.711240436189781
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Rpl36al	ENSMUSG00000049751	0.25141795904251	0.573205482926791	0.392243127063687	0.573205482926791	0.573205482926791	0.573205482926791
Mettl21d	ENSMUSG00000049882	0.255901190956604	0.383851786434906	0.455625354715448	0.455625354715448	0.0964252305385472	0.289275691615642
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Rnf7	ENSMUSG00000051234	0.254414773803597	0.254414773803597	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rnf181	ENSMUSG00000055850	0.703556284613037	0.703556284613037	0.346527959006435	0.519791938509652	0.341647690705446	0.519791938509652
Commd7	ENSMUSG00000056941	0.0328221470541517	0.098466441162455	0.852175490580835	0.852175490580835	0.576112968612194	0.852175490580835
Rpl38	ENSMUSG00000057322	0.254414773803597	0.447621891168214	0.447621891168214	0.447621891168214	0.398829756175299	0.447621891168214
Rpl32	ENSMUSG00000057841	0.297095062262362	0.766645874397711	0.511097249598474	0.766645874397711	0.776919261684345	0.776919261684345
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Rpl10-ps3	ENSMUSG00000058443	0.348008842235184	0.853049270252403	0.853049270252403	0.853049270252403	0.639337105615665	0.853049270252403
Rpl23a	ENSMUSG00000058546	0.255530331334266	0.67143283675232	0.447621891168214	0.67143283675232	0.703556284613037	0.703556284613037
Tmed9	ENSMUSG00000058569	0.214037080764326	0.519791938509652	0.346527959006435	0.519791938509652	0.577259514257969	0.577259514257969
Rpl18	ENSMUSG00000059070	0.146800541856249	0.440401625568746	0.638310022345193	0.92589277149125	0.92589277149125	0.92589277149125
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rpl3	ENSMUSG00000060036	0.148115998140416	0.444347994421247	0.343537039781257	0.515305559671886	0.576973746230334	0.576973746230334
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Rpl26	ENSMUSG00000060938	0.454600801949285	0.853372965654504	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Rpl34	ENSMUSG00000062006	0.5155648232968	0.780851835278818	0.642366752097095	0.780851835278818	0.780851835278818	0.780851835278818
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Chchd1	ENSMUSG00000063787	0.779888212132595	0.779888212132595	0.570836132666921	0.779888212132595	0.395196379647461	0.779888212132595
Aurkaip1	ENSMUSG00000065990	0.11595859961889	0.347875798856669	0.710001140920767	0.78180291566155	0.78180291566155	0.78180291566155
Rplp0	ENSMUSG00000067274	0.252545530864481	0.596076093399921	0.397384062266614	0.596076093399921	0.710001140920767	0.710001140920767
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Dap3	ENSMUSG00000068921	0.11595859961889	0.347875798856669	0.450444934184774	0.452880492349546	0.452880492349546	0.452880492349546
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
B3gnt9	ENSMUSG00000069920	0.392985378348026	0.450444934184774	0.0947558980989551	0.284267694296865	0.450444934184774	0.450444934184774
Ptrh2	ENSMUSG00000072582	0.00768144932639892	0.0230443479791968	0.346899083932133	0.450444934184774	0.450444934184774	0.450444934184774
Commd6	ENSMUSG00000075486	0.252920381501206	0.379380572251809	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028
Dph1	ENSMUSG00000078789	0.211844580334808	0.317766870502212	0.781170242226513	0.781170242226513	0.17924968721805	0.317766870502212
Eif5a	ENSMUSG00000078812	0.00289311433957183	0.0086793430187155	0.00974037464901008	0.0146105619735151	0.640355507848752	0.640355507848752
Hist3h2a	ENSMUSG00000078851	0.926496242814507	0.926496242814507	0.246478961478169	0.369718442217254	0.147787500009832	0.369718442217254
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951
Rpl36a	ENSMUSG00000079435	0.348008842235184	0.711854160331342	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rab7	ENSMUSG00000079477	0.642366752097095	0.711034989117171	0.397384062266614	0.711034989117171	0.711034989117171	0.711034989117171
Rpl39	ENSMUSG00000079641	0.45596561163947	0.683948417459205	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
RPL24	ENSMUSG00000098274	0.204424977646738	0.516994836448954	0.344663224299303	0.516994836448954	0.926441990075769	0.926441990075769

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Formation of the ternary complex, and subsequently, the 43S complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501

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Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Etfb	ENSMUSG00000004610	0.058823267388015	0.0882349010820225	0.0168921052924602	0.0506763158773805	0.567513221841557	0.567513221841557
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Tmem126b	ENSMUSG00000030614	0.397384062266614	0.454600801949285	0.121155015244363	0.363465045733089	0.454600801949285	0.454600801949285
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufaf3	ENSMUSG00000070283	0.0441715176243982	0.132514552873195	0.399548817627028	0.573498913947369	0.573498913947369	0.573498913947369
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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Translation initiation complex formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501

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Ribosomal scanning and start codon recognition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501

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Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps11	ENSMUSG00000003429	0.0761127945805736	0.228338383741721	0.178901132102685	0.268351698154027	0.577259514257969	0.577259514257969
Rps9	ENSMUSG00000006333	0.0441715176243983	0.132514552873195	0.119631084167592	0.179446626251387	0.853801250889739	0.853801250889739
Rps18	ENSMUSG00000008668	0.255901190956604	0.767703572869812	0.926333123228344	0.926550375688041	0.926550375688041	0.926550375688041
Rps15a	ENSMUSG00000008683	0.348008842235184	0.522013263352777	0.348008842235184	0.522013263352777	0.853372965654504	0.853372965654504
Rps25	ENSMUSG00000009927	0.216214347033995	0.648643041101984	0.710001140920767	0.710001140920767	0.642864324224729	0.710001140920767
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rps14	ENSMUSG00000024608	0.11993617140438	0.359808514213139	0.395928178642446	0.593892267963669	0.926658283600152	0.926658283600152
Eif3a	ENSMUSG00000024991	0.11810342389482	0.179446626251387	0.119631084167592	0.179446626251387	0.711034989117171	0.711034989117171
Eif3m	ENSMUSG00000027170	0.5155648232968	0.852832278580641	0.852832278580641	0.852832278580641	0.640861491578951	0.852832278580641
Rps20	ENSMUSG00000028234	0.0964252305385472	0.289275691615642	0.297095062262362	0.445642593393544	0.711854160331342	0.711854160331342
Rps3	ENSMUSG00000030744	0.45596561163947	0.924872384323463	0.924872384323463	0.924872384323463	0.7048795965722	0.924872384323463
Rps4x	ENSMUSG00000031320	0.180293335960318	0.540880007880955	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Rps29	ENSMUSG00000034892	0.18064054691103	0.515305559671886	0.343537039781257	0.515305559671886	1	1
Rps27l	ENSMUSG00000036781	0.144157978128026	0.316665516599712	0.211110344399808	0.316665516599712	0.511742979522636	0.511742979522636
Rps21	ENSMUSG00000039001	0.398829756175299	0.450094379653806	0.342026805366747	0.450094379653806	0.450094379653806	0.450094379653806
Rps19	ENSMUSG00000040952	0.0761127945805735	0.228338383741721	0.507830090867449	0.761745136301173	0.853372965654504	0.853372965654504
Rps8	ENSMUSG00000047675	0.0579478375430677	0.173843512629203	0.148772260628989	0.223158390943484	0.711854160331342	0.711854160331342
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Eif3k	ENSMUSG00000053565	0.148772260628989	0.446316781886968	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155
Eif4a1	ENSMUSG00000059796	0.179945789077372	0.539837367232115	0.514300775319626	0.57466664340579	0.57466664340579	0.57466664340579
Rps15	ENSMUSG00000063457	0.0753654386865988	0.226096316059796	0.640861491578951	0.709375484777034	0.709375484777034	0.709375484777034
Rps28	ENSMUSG00000067288	0.0753654386865988	0.226096316059796	0.216214347033995	0.324321520550992	0.782117202022501	0.782117202022501

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Respiratory electron transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Etfb	ENSMUSG00000004610	0.058823267388015	0.0882349010820225	0.0168921052924602	0.0506763158773805	0.567513221841557	0.567513221841557
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Tmem126b	ENSMUSG00000030614	0.397384062266614	0.454600801949285	0.121155015244363	0.363465045733089	0.454600801949285	0.454600801949285
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufaf3	ENSMUSG00000070283	0.0441715176243982	0.132514552873195	0.399548817627028	0.573498913947369	0.573498913947369	0.573498913947369
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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The citric acid (TCA) cycle and respiratory electron transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Idh3g	ENSMUSG00000002010	0.252545530864481	0.683948417459205	0.45596561163947	0.683948417459205	0.853694531487825	0.853694531487825
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Etfb	ENSMUSG00000004610	0.058823267388015	0.0882349010820225	0.0168921052924602	0.0506763158773805	0.567513221841557	0.567513221841557
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Pdhx	ENSMUSG00000010914	0.452880492349546	0.452880492349546	0.452880492349546	0.452880492349546	0.11810342389482	0.354310271684459
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Glo1	ENSMUSG00000024026	0.701310685803632	0.703556284613037	0.703556284613037	0.703556284613037	0.44726599573338	0.703556284613037
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Tmem126b	ENSMUSG00000030614	0.397384062266614	0.454600801949285	0.121155015244363	0.363465045733089	0.454600801949285	0.454600801949285
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Uqcrq	ENSMUSG00000044894	0.211844580334808	0.250285839267991	0.0566379395854602	0.169913818756381	0.250285839267991	0.250285839267991
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739
Suclg1	ENSMUSG00000052738	0.92622377157404	0.92622377157404	0.852175490580835	0.92622377157404	0.57466664340579	0.92622377157404
Uqcr10	ENSMUSG00000059534	0.288654423610209	0.432981635415313	0.0674166595311035	0.202249978593311	0.710001140920767	0.710001140920767
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufaf3	ENSMUSG00000070283	0.0441715176243982	0.132514552873195	0.399548817627028	0.573498913947369	0.573498913947369	0.573498913947369
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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Formation of RNA Pol II elongation complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Mllt3	ENSMUSG00000028496	0.0741204440774081	0.222361332232224	0.515564823296801	0.773347234945201	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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RNA Polymerase II Transcription Elongation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Mllt3	ENSMUSG00000028496	0.0741204440774081	0.222361332232224	0.515564823296801	0.773347234945201	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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RNA Polymerase II Pre-transcription Events

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Mllt3	ENSMUSG00000028496	0.0741204440774081	0.222361332232224	0.515564823296801	0.773347234945201	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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Transcription-Coupled Nucleotide Excision Repair (TC-NER)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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TP53 Regulates Transcription of DNA Repair Genes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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Complex I biogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ndufb2	ENSMUSG00000002416	0.11810342389482	0.17715513584223	0.0231500557096833	0.06945016712905	0.45596561163947	0.45596561163947
Ndufa2	ENSMUSG00000014294	0.0726276229843141	0.111180666116112	0.0741204440774082	0.111180666116112	0.642366752097095	0.642366752097095
Ndufa1	ENSMUSG00000016427	0.148772260628989	0.223158390943484	0.00481536616919077	0.0144460985075723	0.711240436189781	0.711240436189781
Ndufa5	ENSMUSG00000023089	0.442211413534162	0.442211413534162	0.00540357047972084	0.0162107114391625	0.252920381501207	0.37938057225181
Ndufv3	ENSMUSG00000024038	0.443669460449296	0.576973746230334	0.386972299618399	0.576973746230334	0.576973746230334	0.576973746230334
Ndufb5	ENSMUSG00000027673	0.426190299288673	0.441845139428191	0.101393684899604	0.304181054698813	0.441845139428191	0.441845139428191
Tmem126b	ENSMUSG00000030614	0.397384062266614	0.454600801949285	0.121155015244363	0.363465045733089	0.454600801949285	0.454600801949285
Ndufc2	ENSMUSG00000030647	0.572616808177226	0.78180291566155	0.297095062262362	0.78180291566155	0.78180291566155	0.78180291566155
Ndufb11	ENSMUSG00000031059	0.438516479093275	0.6275332346787	0.6275332346787	0.6275332346787	0.171859370212435	0.515578110637305
Ndufa3	ENSMUSG00000035674	0.0434194723707708	0.0651292085561563	0.0315593554855452	0.0651292085561563	0.711240436189781	0.711240436189781
Ndufa13	ENSMUSG00000036199	0.613238140567788	0.613238140567788	0.306522783017375	0.459784174526062	0.29252580908486	0.459784174526062
Ndufc1	ENSMUSG00000037152	0.154782727227368	0.232174090841052	0.00530065988358761	0.0159019796507628	0.447265995733381	0.447265995733381
Ndufa7	ENSMUSG00000041881	0.0315593554855452	0.0946780664566355	0.208156293081417	0.312234439622125	1	1
Ndufs8	ENSMUSG00000059734	1	1	1	1	0.711240436189781	1
mt-Nd3	ENSMUSG00000064360	0.345410946355104	0.518116419532656	0.0936419271039908	0.280925781311972	1	1
Ndufaf3	ENSMUSG00000070283	0.0441715176243982	0.132514552873195	0.399548817627028	0.573498913947369	0.573498913947369	0.573498913947369
Ndufb6	ENSMUSG00000071014	0.119631084167591	0.179446626251387	0.00695468356472023	0.0208640506941607	0.711854160331342	0.711854160331342

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Gap-filling DNA repair synthesis and ligation in TC-NER

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Formation of the Early Elongation Complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Transcriptional Regulation by TP53

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Ttc5	ENSMUSG00000006288	0.299349060054895	0.575536202757516	0.397384062266614	0.575536202757516	0.575536202757516	0.575536202757516
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Triap1	ENSMUSG00000029535	0.00147557935671113	0.0044267380701334	0.378414240914692	0.567621361372039	0.63250023504486	0.63250023504486
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Pin1	ENSMUSG00000032171	0.0328221470541517	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.575824878403157	0.575824878403157
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cnot3	ENSMUSG00000035632	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Cnot4	ENSMUSG00000038784	0.144820068500793	0.43446020550238	0.300095920620218	0.450143880930327	0.575824878403157	0.575824878403157
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Brpf3	ENSMUSG00000063952	0.782117202022501	0.782117202022501	0.00450646370870541	0.0135193911261162	0.505169133438821	0.757753700158231
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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Dual incision in TC-NER

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Mitochondrial translation elongation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Mrps24	ENSMUSG00000020477	0.214037080764326	0.321055621146488	0.023800255149993	0.0714007654499789	0.576973746230334	0.576973746230334
Eral1	ENSMUSG00000020832	0.0243249029874197	0.0729747089622591	0.0583853430099098	0.0875780145148646	0.0969812105731562	0.0969812105731562
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Mrpl39	ENSMUSG00000022889	0.348008842235184	0.522566341862834	0.926550375688041	0.926550375688041	0.34837756124189	0.522566341862834
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Mrpl53	ENSMUSG00000030037	0.211844580334808	0.323235417174495	0.21549027811633	0.323235417174495	0.447265995733381	0.447265995733381
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Mrps28	ENSMUSG00000040269	0.291756209988535	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Chchd1	ENSMUSG00000063787	0.779888212132595	0.779888212132595	0.570836132666921	0.779888212132595	0.395196379647461	0.779888212132595
Aurkaip1	ENSMUSG00000065990	0.11595859961889	0.347875798856669	0.710001140920767	0.78180291566155	0.78180291566155	0.78180291566155
Dap3	ENSMUSG00000068921	0.11595859961889	0.347875798856669	0.450444934184774	0.452880492349546	0.452880492349546	0.452880492349546

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Formation of TC-NER Pre-Incision Complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Mitochondrial translation termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Mrps24	ENSMUSG00000020477	0.214037080764326	0.321055621146488	0.023800255149993	0.0714007654499789	0.576973746230334	0.576973746230334
Eral1	ENSMUSG00000020832	0.0243249029874197	0.0729747089622591	0.0583853430099098	0.0875780145148646	0.0969812105731562	0.0969812105731562
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Mrpl39	ENSMUSG00000022889	0.348008842235184	0.522566341862834	0.926550375688041	0.926550375688041	0.34837756124189	0.522566341862834
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Mrpl53	ENSMUSG00000030037	0.211844580334808	0.323235417174495	0.21549027811633	0.323235417174495	0.447265995733381	0.447265995733381
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Mrps28	ENSMUSG00000040269	0.291756209988535	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Chchd1	ENSMUSG00000063787	0.779888212132595	0.779888212132595	0.570836132666921	0.779888212132595	0.395196379647461	0.779888212132595
Aurkaip1	ENSMUSG00000065990	0.11595859961889	0.347875798856669	0.710001140920767	0.78180291566155	0.78180291566155	0.78180291566155
Dap3	ENSMUSG00000068921	0.11595859961889	0.347875798856669	0.450444934184774	0.452880492349546	0.452880492349546	0.452880492349546

Download data as csv

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ddx39	ENSMUSG00000005481	0.0236697127745139	0.0710091383235416	0.640861491578951	0.640861491578951	0.640355507848752	0.640861491578951
Zmat5	ENSMUSG00000009076	0.00695468356472021	0.0104320253470803	0.00695468356472022	0.0104320253470803	0.513665062682276	0.513665062682276
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Ppil1	ENSMUSG00000024007	0.0116356061791785	0.0174534092687677	0.0113089139751576	0.0174534092687677	0.78180291566155	0.78180291566155
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Dhx16	ENSMUSG00000024422	0.778911768167544	0.778911768167544	0.058823267388015	0.176469802164045	0.120850531362929	0.181275797044394
Ppil3	ENSMUSG00000026035	0.926658283600152	0.926658283600152	0.576973746230334	0.926658283600152	0.92622377157404	0.926658283600152
Cwc22	ENSMUSG00000027014	0.450094379653806	0.511097249598474	0.395928178642446	0.511097249598474	0.511097249598474	0.511097249598474
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Ctnnbl1	ENSMUSG00000027649	0.577829325134931	0.640861491578951	0.253294730253594	0.640861491578951	0.640861491578951	0.640861491578951
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Hnrnpu	ENSMUSG00000039630	0.395196379647461	0.454600801949285	0.297095062262362	0.454600801949285	0.454600801949285	0.454600801949285
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Snrnp25	ENSMUSG00000040767	0.253294730253594	0.345410946355104	0.119631084167592	0.345410946355104	0.345410946355104	0.345410946355104
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Phf5a	ENSMUSG00000061360	0.11595859961889	0.173937899428335	0.0743693776059065	0.173937899428335	0.640355507848752	0.640355507848752
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Lsm5	ENSMUSG00000091625	0.11993617140438	0.359808514213139	0.347639524025037	0.521459286037555	0.782117202022501	0.782117202022501

Download data as csv

Mitochondrial translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl10	ENSMUSG00000001445	0.00477055016690543	0.0143116505007163	0.0158546704257247	0.023782005638587	0.576112968612194	0.576112968612194
Mrps18c	ENSMUSG00000016833	0.637274134311157	0.637274134311157	0.438889219142351	0.637274134311157	0.390750658104795	0.637274134311157
Mrps24	ENSMUSG00000020477	0.214037080764326	0.321055621146488	0.023800255149993	0.0714007654499789	0.576973746230334	0.576973746230334
Eral1	ENSMUSG00000020832	0.0243249029874197	0.0729747089622591	0.0583853430099098	0.0875780145148646	0.0969812105731562	0.0969812105731562
Mrpl36	ENSMUSG00000021607	0.0434194723707708	0.130258417112313	0.214764523938594	0.322146785907891	0.92622377157404	0.92622377157404
Mrpl39	ENSMUSG00000022889	0.348008842235184	0.522566341862834	0.926550375688041	0.926550375688041	0.34837756124189	0.522566341862834
Mrpl14	ENSMUSG00000023939	0.0441715176243982	0.114542949053818	0.0763619660358786	0.114542949053818	0.711854160331342	0.711854160331342
Mrpl28	ENSMUSG00000024181	0.0331400397096515	0.0497100595644772	0.0162664168407233	0.04879925052217	1	1
Mrpl27	ENSMUSG00000024414	0.0382382535564792	0.0573573803347187	0.0164739112492867	0.0494217337478601	0.399548817627028	0.399548817627028
Mrpl11	ENSMUSG00000024902	0.136812262667828	0.205218394001742	0.0897372356882883	0.205218394001742	0.345037391052887	0.345037391052887
Mrpl30	ENSMUSG00000026087	0.342026805366747	0.51304020805012	0.142165951159432	0.426497853478296	0.514934023620344	0.514934023620344
Mrpl9	ENSMUSG00000028140	0.556076353797516	0.852065168704833	0.633039971999413	0.852065168704833	0.852065168704833	0.852065168704833
Mrpl53	ENSMUSG00000030037	0.211844580334808	0.323235417174495	0.21549027811633	0.323235417174495	0.447265995733381	0.447265995733381
Mrpl3	ENSMUSG00000032563	0.0449262652924809	0.134778795877443	0.179945789077372	0.269918683616058	0.514934023620344	0.514934023620344
Mrps28	ENSMUSG00000040269	0.291756209988535	0.57466664340579	0.57466664340579	0.57466664340579	0.400265374208515	0.57466664340579
Mrps16	ENSMUSG00000049960	0.708534948098331	0.708745765211584	0.113190884633071	0.339572653899213	0.708745765211584	0.708745765211584
Mrpl35	ENSMUSG00000052962	0.926496242814507	0.926496242814507	0.926387617028817	0.926496242814507	0.345037391052887	0.926496242814507
Mrps14	ENSMUSG00000058267	0.640355507848752	0.640355507848752	0.329176790045262	0.493765185067894	0.254787123615606	0.493765185067894
Chchd1	ENSMUSG00000063787	0.779888212132595	0.779888212132595	0.570836132666921	0.779888212132595	0.395196379647461	0.779888212132595
Aurkaip1	ENSMUSG00000065990	0.11595859961889	0.347875798856669	0.710001140920767	0.78180291566155	0.78180291566155	0.78180291566155
Dap3	ENSMUSG00000068921	0.11595859961889	0.347875798856669	0.450444934184774	0.452880492349546	0.452880492349546	0.452880492349546

Download data as csv

mRNA Splicing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Zmat5	ENSMUSG00000009076	0.00695468356472021	0.0104320253470803	0.00695468356472022	0.0104320253470803	0.513665062682276	0.513665062682276
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Ppil1	ENSMUSG00000024007	0.0116356061791785	0.0174534092687677	0.0113089139751576	0.0174534092687677	0.78180291566155	0.78180291566155
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Dhx16	ENSMUSG00000024422	0.778911768167544	0.778911768167544	0.058823267388015	0.176469802164045	0.120850531362929	0.181275797044394
Ppil3	ENSMUSG00000026035	0.926658283600152	0.926658283600152	0.576973746230334	0.926658283600152	0.92622377157404	0.926658283600152
Cwc22	ENSMUSG00000027014	0.450094379653806	0.511097249598474	0.395928178642446	0.511097249598474	0.511097249598474	0.511097249598474
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Ctnnbl1	ENSMUSG00000027649	0.577829325134931	0.640861491578951	0.253294730253594	0.640861491578951	0.640861491578951	0.640861491578951
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Hnrnpu	ENSMUSG00000039630	0.395196379647461	0.454600801949285	0.297095062262362	0.454600801949285	0.454600801949285	0.454600801949285
Snrnp25	ENSMUSG00000040767	0.253294730253594	0.345410946355104	0.119631084167592	0.345410946355104	0.345410946355104	0.345410946355104
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Phf5a	ENSMUSG00000061360	0.11595859961889	0.173937899428335	0.0743693776059065	0.173937899428335	0.640355507848752	0.640355507848752
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Lsm5	ENSMUSG00000091625	0.11993617140438	0.359808514213139	0.347639524025037	0.521459286037555	0.782117202022501	0.782117202022501

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RNA Pol II CTD phosphorylation and interaction with CE

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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mRNA Splicing - Minor Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Zmat5	ENSMUSG00000009076	0.00695468356472021	0.0104320253470803	0.00695468356472022	0.0104320253470803	0.513665062682276	0.513665062682276
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Snrnp25	ENSMUSG00000040767	0.253294730253594	0.345410946355104	0.119631084167592	0.345410946355104	0.345410946355104	0.345410946355104
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1

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APC/C:Cdc20 mediated degradation of Securin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Nucleotide Excision Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Sumo3	ENSMUSG00000020265	0.398108175780842	0.398108175780842	0.246861959455465	0.370292939183197	0.246861959455465	0.370292939183197
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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mRNA Capping

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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mRNA Splicing - Major Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Ppil1	ENSMUSG00000024007	0.0116356061791785	0.0174534092687677	0.0113089139751576	0.0174534092687677	0.78180291566155	0.78180291566155
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Dhx16	ENSMUSG00000024422	0.778911768167544	0.778911768167544	0.058823267388015	0.176469802164045	0.120850531362929	0.181275797044394
Ppil3	ENSMUSG00000026035	0.926658283600152	0.926658283600152	0.576973746230334	0.926658283600152	0.92622377157404	0.926658283600152
Cwc22	ENSMUSG00000027014	0.450094379653806	0.511097249598474	0.395928178642446	0.511097249598474	0.511097249598474	0.511097249598474
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Ctnnbl1	ENSMUSG00000027649	0.577829325134931	0.640861491578951	0.253294730253594	0.640861491578951	0.640861491578951	0.640861491578951
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Hnrnpu	ENSMUSG00000039630	0.395196379647461	0.454600801949285	0.297095062262362	0.454600801949285	0.454600801949285	0.454600801949285
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Hnrnpa3	ENSMUSG00000059005	0.0426702157436794	0.128010647231038	0.344663224299303	0.344663224299303	0.254787123615605	0.344663224299303
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Phf5a	ENSMUSG00000061360	0.11595859961889	0.173937899428335	0.0743693776059065	0.173937899428335	0.640355507848752	0.640355507848752
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Sf3b5	ENSMUSG00000078348	0.213307944885796	0.319961917328694	0.058823267388015	0.176469802164045	0.573498913947369	0.573498913947369
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Lsm5	ENSMUSG00000091625	0.11993617140438	0.359808514213139	0.347639524025037	0.521459286037555	0.782117202022501	0.782117202022501

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Separation of Sister Chromatids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

Download data as csv

Mitotic Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Emd	ENSMUSG00000001964	0.777922216623952	0.777922216623952	0.178901132102685	0.536703396308054	0.5155648232968	0.7733472349452
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

Download data as csv

Mitotic Metaphase and Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Emd	ENSMUSG00000001964	0.777922216623952	0.777922216623952	0.178901132102685	0.536703396308054	0.5155648232968	0.7733472349452
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase II Promoter Escape

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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RNA Polymerase II Transcription Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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RNA Polymerase II Transcription Initiation And Promoter Clearance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cell Cycle Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Rnf8	ENSMUSG00000090083	0.511742979522636	0.511742979522636	0.345410946355104	0.511742979522636	0.297848640636702	0.511742979522636

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DNA Replication

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Degradation of beta-catenin by the destruction complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ctbp2	ENSMUSG00000030970	0.853480389728993	0.926550375688041	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase I Promoter Escape

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rrn3	ENSMUSG00000022682	0.78148726569172	0.78148726569172	0.643359829732651	0.78148726569172	0.400265374208515	0.78148726569172
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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CDT1 association with the CDC6:ORC:origin complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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CDK-mediated phosphorylation and removal of Cdc6

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Synthesis of DNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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FGFR2 alternative splicing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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APC/C-mediated degradation of cell cycle proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Regulation of mitotic cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Hedgehog ligand biogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Scube2	ENSMUSG00000007279	0.120545895661628	0.296717426617604	0.254041925545275	0.296717426617604	0.296717426617604	0.296717426617604
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Os9	ENSMUSG00000040462	0.782117202022501	0.926550375688041	0.853480389728993	0.926550375688041	0.926550375688041	0.926550375688041
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Neddylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fbxo7	ENSMUSG00000001786	0.173632433887832	0.367990297261757	0.245326864841171	0.367990297261757	0.92622377157404	0.92622377157404
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Fbxw9	ENSMUSG00000008167	0.509798138101151	0.764697207151727	0.0763619660358786	0.229085898107636	0.7802108304765	0.7802108304765
Nedd8	ENSMUSG00000010376	0.0852666932085725	0.255800079625717	0.297095062262362	0.445642593393544	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Socs2	ENSMUSG00000020027	0.00264953297731414	0.00794859893194243	0.642864324224729	0.642864324224729	0.450794830295118	0.642864324224729
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Commd9	ENSMUSG00000027163	0.213307944885796	0.639923834657388	0.455625354715448	0.683438032073173	0.92622377157404	0.92622377157404
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Fbxo17	ENSMUSG00000030598	0.0805126803503835	0.120769020525575	0.0239310464924689	0.0717931394774068	0.635966700067775	0.635966700067775
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Asb11	ENSMUSG00000031382	1	1	0.400265374208515	0.865460619345501	0.576973746230334	0.865460619345501
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Commd4	ENSMUSG00000032299	0.148115998140415	0.444347994421246	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781
Tulp4	ENSMUSG00000034377	0.093084640707941	0.21723010275119	0.144820068500793	0.21723010275119	0.513665062682276	0.513665062682276
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Commd2	ENSMUSG00000036513	0.0763619660358786	0.114542949053818	0.0583853430099097	0.114542949053818	0.514934023620345	0.514934023620345
Commd10	ENSMUSG00000042705	0.00283103937188883	0.00849311811566649	0.344663224299303	0.516994836448954	0.853801250889739	0.853801250889739
Fbxl13	ENSMUSG00000048520	0.711240436189781	0.711240436189781	0.514934023620345	0.711240436189781	0.341647690705446	0.711240436189781
Rnf7	ENSMUSG00000051234	0.254414773803597	0.254414773803597	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Commd7	ENSMUSG00000056941	0.0328221470541517	0.098466441162455	0.852175490580835	0.852175490580835	0.576112968612194	0.852175490580835
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Commd6	ENSMUSG00000075486	0.252920381501206	0.379380572251809	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Emd	ENSMUSG00000001964	0.777922216623952	0.777922216623952	0.178901132102685	0.536703396308054	0.5155648232968	0.7733472349452
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Ncaph2	ENSMUSG00000008690	0.01710279005982	0.0513083701794599	0.147458757705094	0.221188136557642	0.255530331334266	0.255530331334266
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Phlda1	ENSMUSG00000020205	0.779238691542963	0.926550375688041	0.708323672944427	0.926550375688041	0.926550375688041	0.926550375688041
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ten1	ENSMUSG00000020778	0.0325051220296005	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.576112968612194	0.576112968612194
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Mis18a	ENSMUSG00000022978	0.348008842235184	0.522013263352776	0.344663224299303	0.522013263352776	0.853694531487825	0.853694531487825
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Esco1	ENSMUSG00000024293	1	1	0.643853282854191	1	0.852504981253341	1
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Ssna1	ENSMUSG00000026966	0.0150443553124285	0.0451330659372853	0.0548979200435556	0.0823468800653334	0.710208797518812	0.710208797518812
Nop10	ENSMUSG00000027133	0.514300775319626	0.771451162979439	0.297848640636702	0.771451162979439	1	1
Haus2	ENSMUSG00000027285	0.121155015244363	0.363465045733089	0.853480389728993	0.853480389728993	0.300095920620218	0.450143880930327
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Cdk11b	ENSMUSG00000029062	0.346527959006435	1	1	1	0.782117202022501	1
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Mzt1	ENSMUSG00000033186	0.853372965654504	0.853372965654504	0.643853282854191	0.853372965654504	0.782117202022501	0.853372965654504
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Rsf1	ENSMUSG00000035623	0.0964252305385472	0.144637845807821	0.0763619660358786	0.144637845807821	0.575536202757516	0.575536202757516
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Haus1	ENSMUSG00000041840	0.115037265385284	0.345111796155853	0.450794830295118	0.450794830295118	0.346899083932133	0.450794830295118
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Fgfr1op	ENSMUSG00000069135	0.254787123615605	0.382180685423408	0.642366752097095	0.642366752097095	0.254787123615605	0.382180685423408
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Cenpw	ENSMUSG00000075266	0.255530331334266	0.383851786434906	0.255901190956604	0.383851786434906	0.514934023620345	0.514934023620345
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Rnf8	ENSMUSG00000090083	0.511742979522636	0.511742979522636	0.345410946355104	0.511742979522636	0.297848640636702	0.511742979522636

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Degradation of DVL

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Klhl12	ENSMUSG00000026455	0.0116356061791785	0.0349068185375355	0.21549027811633	0.323235417174495	0.853372965654504	0.853372965654504
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cellular responses to stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp6v1f	ENSMUSG00000004285	0.0523032931247597	0.156909879374279	0.208897379073412	0.313346068610118	0.641867098978198	0.641867098978198
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Dnajb1	ENSMUSG00000005483	0.254414773803597	0.682414427663012	0.92622377157404	0.92622377157404	0.454942951775342	0.682414427663012
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Atp6v0e	ENSMUSG00000015575	0.509144723230069	0.763717084845103	0.92416823462528	0.92416823462528	0.386972299618399	0.763717084845103
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
St13	ENSMUSG00000022403	0.0236697127745139	0.0710091383235417	0.0763619660358786	0.114542949053818	0.575824878403157	0.575824878403157
Rps6ka2	ENSMUSG00000023809	0.299349060054895	0.299349060054895	0.177153312234059	0.265729968351089	0.148115998140415	0.265729968351089
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Prdx3	ENSMUSG00000024997	0.779888212132595	0.852832278580641	0.852832278580641	0.852832278580641	0.711240436189781	0.852832278580641
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Dnaja1	ENSMUSG00000028410	0.0115535350288052	0.0346606050864156	0.120545895661628	0.180818843492441	0.853480389728993	0.853480389728993
Nudt2	ENSMUSG00000028443	0.120850531362929	0.362551594088788	0.577829325134931	0.853801250889739	0.853801250889739	0.853801250889739
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Hsbp1	ENSMUSG00000031839	0.347639524025037	0.521459286037555	0.000157492167861666	0.000472476503584999	0.853480389728993	0.853480389728993
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Map2k4	ENSMUSG00000033352	0.777922216623952	0.777922216623952	0.0953125666339397	0.285937699901819	0.398108175780842	0.597162263671263
Atp6v1h	ENSMUSG00000033793	0.0548979200435555	0.164693760130667	0.161774914569557	0.242662371854336	0.346899083932133	0.346899083932133
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Eef1a1	ENSMUSG00000037742	0.0761127945805735	0.228338383741721	0.451840588205062	0.575824878403157	0.575824878403157	0.575824878403157
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Bag5	ENSMUSG00000049792	0.78180291566155	0.78180291566155	0.346527959006435	0.78180291566155	0.640861491578951	0.78180291566155
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Jun	ENSMUSG00000052684	0.0241933715424143	0.0725801146272428	0.853907737111068	0.853907737111068	0.299349060054895	0.449023590082343
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951

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Regulation of RUNX2 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Ubiquitin-dependent degradation of Cyclin D

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cellular responses to external stimuli

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp6v1f	ENSMUSG00000004285	0.0523032931247597	0.156909879374279	0.208897379073412	0.313346068610118	0.641867098978198	0.641867098978198
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Dnajb1	ENSMUSG00000005483	0.254414773803597	0.682414427663012	0.92622377157404	0.92622377157404	0.454942951775342	0.682414427663012
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Atp6v0e	ENSMUSG00000015575	0.509144723230069	0.763717084845103	0.92416823462528	0.92416823462528	0.386972299618399	0.763717084845103
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
St13	ENSMUSG00000022403	0.0236697127745139	0.0710091383235417	0.0763619660358786	0.114542949053818	0.575824878403157	0.575824878403157
Rps6ka2	ENSMUSG00000023809	0.299349060054895	0.299349060054895	0.177153312234059	0.265729968351089	0.148115998140415	0.265729968351089
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Prdx3	ENSMUSG00000024997	0.779888212132595	0.852832278580641	0.852832278580641	0.852832278580641	0.711240436189781	0.852832278580641
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Dnaja1	ENSMUSG00000028410	0.0115535350288052	0.0346606050864156	0.120545895661628	0.180818843492441	0.853480389728993	0.853480389728993
Nudt2	ENSMUSG00000028443	0.120850531362929	0.362551594088788	0.577829325134931	0.853801250889739	0.853801250889739	0.853801250889739
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Gpx7	ENSMUSG00000028597	0.300095920620218	0.514300775319626	0.45596561163947	0.514300775319626	0.514300775319626	0.514300775319626
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Hsbp1	ENSMUSG00000031839	0.347639524025037	0.521459286037555	0.000157492167861666	0.000472476503584999	0.853480389728993	0.853480389728993
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Map2k4	ENSMUSG00000033352	0.777922216623952	0.777922216623952	0.0953125666339397	0.285937699901819	0.398108175780842	0.597162263671263
Atp6v1h	ENSMUSG00000033793	0.0548979200435555	0.164693760130667	0.161774914569557	0.242662371854336	0.346899083932133	0.346899083932133
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Eef1a1	ENSMUSG00000037742	0.0761127945805735	0.228338383741721	0.451840588205062	0.575824878403157	0.575824878403157	0.575824878403157
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Bag5	ENSMUSG00000049792	0.78180291566155	0.78180291566155	0.346527959006435	0.78180291566155	0.640861491578951	0.78180291566155
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Jun	ENSMUSG00000052684	0.0241933715424143	0.0725801146272428	0.853907737111068	0.853907737111068	0.299349060054895	0.449023590082343
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951

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Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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GLI3 is processed to GLI3R by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Gene expression (Transcription)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Ell2	ENSMUSG00000001542	0.0766111619812296	0.229833485943689	0.346899083932133	0.520348625898199	0.926333123228344	0.926333123228344
Tead3	ENSMUSG00000002249	0.18064054691103	0.449023590082343	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Ddx39	ENSMUSG00000005481	0.0236697127745139	0.0710091383235416	0.640861491578951	0.640861491578951	0.640355507848752	0.640861491578951
Ctcf	ENSMUSG00000005698	0.399548817627028	0.599323226440542	0.254414773803597	0.599323226440542	0.711650020253571	0.711650020253571
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Ttc5	ENSMUSG00000006288	0.299349060054895	0.575536202757516	0.397384062266614	0.575536202757516	0.575536202757516	0.575536202757516
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Zkscan6	ENSMUSG00000018347	0.00276975149305653	0.00830925447916959	0.575824878403157	0.711034989117171	0.711034989117171	0.711034989117171
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Hdac7	ENSMUSG00000022475	0.072378961026407	0.217136883079221	0.450794830295118	0.450794830295118	0.337435786255284	0.450794830295118
Rrn3	ENSMUSG00000022682	0.78148726569172	0.78148726569172	0.643359829732651	0.78148726569172	0.400265374208515	0.78148726569172
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Tsn	ENSMUSG00000026374	0.0953125666339398	0.285937699901819	0.300095920620218	0.450143880930327	0.514300775319626	0.514300775319626
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Dnmt3b	ENSMUSG00000027478	0.0114717288267218	0.0233230904825838	0.781960228679124	0.781960228679124	0.0155487269883892	0.0233230904825838
Ctsk	ENSMUSG00000028111	0.148115998140416	0.323235417174496	0.21549027811633	0.323235417174496	0.513665062682276	0.513665062682276
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Mllt3	ENSMUSG00000028496	0.0741204440774081	0.222361332232224	0.515564823296801	0.773347234945201	1	1
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Cpsf3l	ENSMUSG00000029034	0.146800541856249	0.400265374208515	0.400265374208515	0.400265374208515	0.348008842235184	0.400265374208515
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Triap1	ENSMUSG00000029535	0.00147557935671113	0.0044267380701334	0.378414240914692	0.567621361372039	0.63250023504486	0.63250023504486
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Auts2	ENSMUSG00000029673	0.11993617140438	0.359808514213139	0.254787123615605	0.382180685423408	0.455625354715448	0.455625354715448
Zkscan1	ENSMUSG00000029729	0.0756145297453648	0.113421794618047	0.0756145297453648	0.113421794618047	0.400265374208515	0.400265374208515
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Pin1	ENSMUSG00000032171	0.0328221470541517	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.575824878403157	0.575824878403157
Tcf12	ENSMUSG00000032228	0.0886202385494145	0.132930357824122	0.0886202385494145	0.132930357824122	0.853372965654504	0.853372965654504
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cnot3	ENSMUSG00000035632	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017
Polr3g	ENSMUSG00000035834	0.0753654386865988	0.226096316059796	0.299349060054895	0.449023590082343	0.708534948098331	0.708534948098331
Kctd1	ENSMUSG00000036225	0.344663224299303	0.521459286037555	0.78180291566155	0.78180291566155	0.347639524025037	0.521459286037555
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Cnot4	ENSMUSG00000038784	0.144820068500793	0.43446020550238	0.300095920620218	0.450143880930327	0.575824878403157	0.575824878403157
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Zfp750	ENSMUSG00000039238	0.053382016116041	0.0813711899786324	0.241452668344062	0.241452668344062	0.0542474599857549	0.0813711899786324
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Zfp560	ENSMUSG00000045519	0.00159435459956481	0.00478306379869442	0.148115998140416	0.148115998140416	0.0334587898203823	0.0501881847305735
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Zfp212	ENSMUSG00000052763	0.00468160475316412	0.0140448142594924	0.0763619660358787	0.114542949053818	0.853372965654504	0.853372965654504
Zfp472	ENSMUSG00000053600	0.511742979522636	0.860248370921054	0.573498913947369	0.860248370921054	0.92622377157404	0.92622377157404
Zkscan5	ENSMUSG00000055991	0.45596561163947	0.45596561163947	0.0113901882503033	0.0341705647509098	0.0232795908282423	0.0349193862423634
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Zfp945	ENSMUSG00000059142	0.246861959455465	0.740585878366394	0.853480389728993	0.853480389728993	0.782117202022501	0.853480389728993
Mamld1	ENSMUSG00000059401	0.0113089139751575	0.0339267419254726	0.45596561163947	0.683948417459205	0.926003599371282	0.926003599371282
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Brpf3	ENSMUSG00000063952	0.782117202022501	0.782117202022501	0.00450646370870541	0.0135193911261162	0.505169133438821	0.757753700158231
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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p53-Independent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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p53-Independent DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Switching of origins to a post-replicative state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Autodegradation of the E3 ubiquitin ligase COP1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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DNA Replication Pre-Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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S Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Esco1	ENSMUSG00000024293	1	1	0.643853282854191	1	0.852504981253341	1
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Assembly of the pre-replicative complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Degradation of AXIN

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Regulation of RUNX3 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase I Transcription Termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Cellular response to hypoxia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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Transcriptional regulation by RUNX3

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tead3	ENSMUSG00000002249	0.18064054691103	0.449023590082343	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Mamld1	ENSMUSG00000059401	0.0113089139751575	0.0339267419254726	0.45596561163947	0.683948417459205	0.926003599371282	0.926003599371282
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase I Transcription Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rrn3	ENSMUSG00000022682	0.78148726569172	0.78148726569172	0.643359829732651	0.78148726569172	0.400265374208515	0.78148726569172
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Stabilization of p53

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase I Promoter Clearance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rrn3	ENSMUSG00000022682	0.78148726569172	0.78148726569172	0.643359829732651	0.78148726569172	0.400265374208515	0.78148726569172
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Degradation of GLI1 by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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NIK–>noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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MAPK6/MAPK4 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dnajb1	ENSMUSG00000005483	0.254414773803597	0.682414427663012	0.92622377157404	0.92622377157404	0.454942951775342	0.682414427663012
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Kalrn	ENSMUSG00000061751	0.180293335960318	0.540880007880955	0.711034989117171	0.711034989117171	0.573205482926791	0.711034989117171
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase I Transcription

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rrn3	ENSMUSG00000022682	0.78148726569172	0.78148726569172	0.643359829732651	0.78148726569172	0.400265374208515	0.78148726569172
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Regulation of ornithine decarboxylase (ODC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nqo1	ENSMUSG00000003849	0.214764523938594	0.644293571815781	1	1	0.853480389728993	1
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RNA Polymerase II Transcription

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Ell2	ENSMUSG00000001542	0.0766111619812296	0.229833485943689	0.346899083932133	0.520348625898199	0.926333123228344	0.926333123228344
Tead3	ENSMUSG00000002249	0.18064054691103	0.449023590082343	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Ddx39	ENSMUSG00000005481	0.0236697127745139	0.0710091383235416	0.640861491578951	0.640861491578951	0.640355507848752	0.640861491578951
Ctcf	ENSMUSG00000005698	0.399548817627028	0.599323226440542	0.254414773803597	0.599323226440542	0.711650020253571	0.711650020253571
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Ttc5	ENSMUSG00000006288	0.299349060054895	0.575536202757516	0.397384062266614	0.575536202757516	0.575536202757516	0.575536202757516
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Zkscan6	ENSMUSG00000018347	0.00276975149305653	0.00830925447916959	0.575824878403157	0.711034989117171	0.711034989117171	0.711034989117171
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Hdac7	ENSMUSG00000022475	0.072378961026407	0.217136883079221	0.450794830295118	0.450794830295118	0.337435786255284	0.450794830295118
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ctsk	ENSMUSG00000028111	0.148115998140416	0.323235417174496	0.21549027811633	0.323235417174496	0.513665062682276	0.513665062682276
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Mllt3	ENSMUSG00000028496	0.0741204440774081	0.222361332232224	0.515564823296801	0.773347234945201	1	1
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Cpsf3l	ENSMUSG00000029034	0.146800541856249	0.400265374208515	0.400265374208515	0.400265374208515	0.348008842235184	0.400265374208515
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Triap1	ENSMUSG00000029535	0.00147557935671113	0.0044267380701334	0.378414240914692	0.567621361372039	0.63250023504486	0.63250023504486
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Auts2	ENSMUSG00000029673	0.11993617140438	0.359808514213139	0.254787123615605	0.382180685423408	0.455625354715448	0.455625354715448
Zkscan1	ENSMUSG00000029729	0.0756145297453648	0.113421794618047	0.0756145297453648	0.113421794618047	0.400265374208515	0.400265374208515
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Pin1	ENSMUSG00000032171	0.0328221470541517	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.575824878403157	0.575824878403157
Tcf12	ENSMUSG00000032228	0.0886202385494145	0.132930357824122	0.0886202385494145	0.132930357824122	0.853372965654504	0.853372965654504
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cnot3	ENSMUSG00000035632	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017
Kctd1	ENSMUSG00000036225	0.344663224299303	0.521459286037555	0.78180291566155	0.78180291566155	0.347639524025037	0.521459286037555
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Cnot4	ENSMUSG00000038784	0.144820068500793	0.43446020550238	0.300095920620218	0.450143880930327	0.575824878403157	0.575824878403157
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Zfp750	ENSMUSG00000039238	0.053382016116041	0.0813711899786324	0.241452668344062	0.241452668344062	0.0542474599857549	0.0813711899786324
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Zfp560	ENSMUSG00000045519	0.00159435459956481	0.00478306379869442	0.148115998140416	0.148115998140416	0.0334587898203823	0.0501881847305735
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Zfp212	ENSMUSG00000052763	0.00468160475316412	0.0140448142594924	0.0763619660358787	0.114542949053818	0.853372965654504	0.853372965654504
Zfp472	ENSMUSG00000053600	0.511742979522636	0.860248370921054	0.573498913947369	0.860248370921054	0.92622377157404	0.92622377157404
Zkscan5	ENSMUSG00000055991	0.45596561163947	0.45596561163947	0.0113901882503033	0.0341705647509098	0.0232795908282423	0.0349193862423634
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Zfp945	ENSMUSG00000059142	0.246861959455465	0.740585878366394	0.853480389728993	0.853480389728993	0.782117202022501	0.853480389728993
Mamld1	ENSMUSG00000059401	0.0113089139751575	0.0339267419254726	0.45596561163947	0.683948417459205	0.926003599371282	0.926003599371282
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Brpf3	ENSMUSG00000063952	0.782117202022501	0.782117202022501	0.00450646370870541	0.0135193911261162	0.505169133438821	0.757753700158231
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

Download data as csv

Cell Cycle, Mitotic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Emd	ENSMUSG00000001964	0.777922216623952	0.777922216623952	0.178901132102685	0.536703396308054	0.5155648232968	0.7733472349452
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Ncaph2	ENSMUSG00000008690	0.01710279005982	0.0513083701794599	0.147458757705094	0.221188136557642	0.255530331334266	0.255530331334266
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Phlda1	ENSMUSG00000020205	0.779238691542963	0.926550375688041	0.708323672944427	0.926550375688041	0.926550375688041	0.926550375688041
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Esco1	ENSMUSG00000024293	1	1	0.643853282854191	1	0.852504981253341	1
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Ssna1	ENSMUSG00000026966	0.0150443553124285	0.0451330659372853	0.0548979200435556	0.0823468800653334	0.710208797518812	0.710208797518812
Haus2	ENSMUSG00000027285	0.121155015244363	0.363465045733089	0.853480389728993	0.853480389728993	0.300095920620218	0.450143880930327
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Cdk11b	ENSMUSG00000029062	0.346527959006435	1	1	1	0.782117202022501	1
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Mzt1	ENSMUSG00000033186	0.853372965654504	0.853372965654504	0.643853282854191	0.853372965654504	0.782117202022501	0.853372965654504
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Haus1	ENSMUSG00000041840	0.115037265385284	0.345111796155853	0.450794830295118	0.450794830295118	0.346899083932133	0.450794830295118
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Fgfr1op	ENSMUSG00000069135	0.254787123615605	0.382180685423408	0.642366752097095	0.642366752097095	0.254787123615605	0.382180685423408
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Hedgehog ‘on’ state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Dzip1	ENSMUSG00000042156	0.711240436189781	0.926550375688041	0.711240436189781	0.926550375688041	0.926550375688041	0.926550375688041
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Metabolism of polyamines

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nqo1	ENSMUSG00000003849	0.214764523938594	0.644293571815781	1	1	0.853480389728993	1
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Sat1	ENSMUSG00000025283	0.926003599371282	0.926003599371282	0.451840588205062	0.677760882307593	0.450794830295118	0.677760882307593
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Post-translational protein modification

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fbxo7	ENSMUSG00000001786	0.173632433887832	0.367990297261757	0.245326864841171	0.367990297261757	0.92622377157404	0.92622377157404
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Etfb	ENSMUSG00000004610	0.058823267388015	0.0882349010820225	0.0168921052924602	0.0506763158773805	0.567513221841557	0.567513221841557
Rab11a	ENSMUSG00000004771	0.147458757705094	0.442376273115283	0.455625354715448	0.455625354715448	0.346527959006434	0.455625354715448
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Fbxw9	ENSMUSG00000008167	0.509798138101151	0.764697207151727	0.0763619660358786	0.229085898107636	0.7802108304765	0.7802108304765
Rab25	ENSMUSG00000008601	0.513665062682276	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Nedd8	ENSMUSG00000010376	0.0852666932085725	0.255800079625717	0.297095062262362	0.445642593393544	0.643359829732651	0.643359829732651
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Rab5a	ENSMUSG00000017831	0.256271555563966	0.299349060054895	0.255901190956604	0.299349060054895	0.299349060054895	0.299349060054895
B4galt5	ENSMUSG00000017929	0.78148726569172	0.78180291566155	0.638310022345193	0.78180291566155	0.78180291566155	0.78180291566155
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Cog1	ENSMUSG00000018661	0.780851835278817	1	1	1	0.514934023620344	1
Rab5c	ENSMUSG00000019173	0.398108175780842	1	1	1	0.926658283600152	1
Fkbp8	ENSMUSG00000019428	0.0334587898203823	0.100376369461147	0.216214347033995	0.324321520550992	0.926658283600152	0.926658283600152
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Socs2	ENSMUSG00000020027	0.00264953297731414	0.00794859893194243	0.642864324224729	0.642864324224729	0.450794830295118	0.642864324224729
Sumo3	ENSMUSG00000020265	0.398108175780842	0.398108175780842	0.246861959455465	0.370292939183197	0.246861959455465	0.370292939183197
Fstl3	ENSMUSG00000020325	0.7802108304765	0.7802108304765	0.454942951775341	0.682414427663012	0.297848640636702	0.682414427663012
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Fut8	ENSMUSG00000021065	0.252920381501207	0.588364690595531	0.926550375688041	0.926550375688041	0.392243127063687	0.588364690595531
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Ripk1	ENSMUSG00000021408	0.577829325134931	0.782117202022501	0.044737329683373	0.134211989050119	0.782117202022501	0.782117202022501
Dph3	ENSMUSG00000021905	0.711240436189781	0.853801250889739	0.853801250889739	0.853801250889739	0.710001140920767	0.853801250889739
N6amt2	ENSMUSG00000021951	0.345037391052887	0.577829325134931	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Hdac7	ENSMUSG00000022475	0.072378961026407	0.217136883079221	0.450794830295118	0.450794830295118	0.337435786255284	0.450794830295118
Gpaa1	ENSMUSG00000022561	0.0334587898203824	0.100376369461147	0.346527959006435	0.519791938509652	0.642366752097095	0.642366752097095
Tsta3	ENSMUSG00000022570	0.254414773803597	0.763244321410791	0.5155648232968	0.7733472349452	1	1
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mfi2	ENSMUSG00000022780	0.119020462826154	0.178530694239232	0.00472596298562399	0.014177888956872	0.250663719290221	0.250663719290221
Usp25	ENSMUSG00000022867	0.578113371816017	0.853801250889739	0.300095920620218	0.853801250889739	0.853801250889739	0.853801250889739
Kng1	ENSMUSG00000022875	0.710001140920767	0.710001140920767	0.120241108790035	0.360723326370104	0.298974794311434	0.448462191467151
Pigp	ENSMUSG00000022940	0.256271555563966	0.384407333345949	0.450094379653806	0.450094379653806	0.254787123615605	0.384407333345949
Pigf	ENSMUSG00000024145	0.640861491578951	0.708745765211584	0.249907451332337	0.708745765211584	0.708745765211584	0.708745765211584
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Wac	ENSMUSG00000024283	0.119631084167592	0.324321520550992	0.216214347033995	0.324321520550992	0.514934023620344	0.514934023620344
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Gbf1	ENSMUSG00000025224	0.146141353215796	0.219212029823694	0.0936419271039908	0.219212029823694	1	1
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Pigc	ENSMUSG00000026698	0.925387810388836	0.925387810388836	0.088340911853132	0.265022735559396	0.924814453025535	0.925387810388836
Dpm2	ENSMUSG00000026810	0.0230207752632622	0.0345311628948933	0.00400309634280189	0.0120092890284057	0.575536202757516	0.575536202757516
Ifih1	ENSMUSG00000026896	0.778911768167544	0.778911768167544	0.00477055016690543	0.0143116505007163	0.709375484777034	0.778911768167544
Commd9	ENSMUSG00000027163	0.213307944885796	0.639923834657388	0.455625354715448	0.683438032073173	0.92622377157404	0.92622377157404
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Dnmt3b	ENSMUSG00000027478	0.0114717288267218	0.0233230904825838	0.781960228679124	0.781960228679124	0.0155487269883892	0.0233230904825838
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Ptp4a2	ENSMUSG00000028788	0.711650020253571	0.926441990075769	0.398829756175299	0.926441990075769	0.926441990075769	0.926441990075769
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Fbxo17	ENSMUSG00000030598	0.0805126803503835	0.120769020525575	0.0239310464924689	0.0717931394774068	0.635966700067775	0.635966700067775
Rab6a	ENSMUSG00000030704	0.0097403746490101	0.0292211239470303	0.091411676944639	0.137117515416958	0.92622377157404	0.92622377157404
Rab39b	ENSMUSG00000031202	0.712057867818062	0.853801250889739	0.454600801949285	0.853801250889739	0.853801250889739	0.853801250889739
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Asb11	ENSMUSG00000031382	1	1	0.400265374208515	0.865460619345501	0.576973746230334	0.865460619345501
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Arcn1	ENSMUSG00000032096	0.00755778364492933	0.011336675467394	0.00743512899358789	0.011336675467394	0.399548817627028	0.399548817627028
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Commd4	ENSMUSG00000032299	0.148115998140415	0.444347994421246	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781
Ube2q2	ENSMUSG00000032307	0.398108175780842	0.770497594023414	0.853372965654504	0.853372965654504	0.513665062682276	0.770497594023414
Usp3	ENSMUSG00000032376	0.0761127945805735	0.145471815859734	0.0969812105731561	0.145471815859734	0.399548817627028	0.399548817627028
Tulp4	ENSMUSG00000034377	0.093084640707941	0.21723010275119	0.144820068500793	0.21723010275119	0.513665062682276	0.513665062682276
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Nagk	ENSMUSG00000034744	0.00153425095635555	0.00460275286906664	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Commd2	ENSMUSG00000036513	0.0763619660358786	0.114542949053818	0.0583853430099097	0.114542949053818	0.514934023620345	0.514934023620345
Eef1a1	ENSMUSG00000037742	0.0761127945805735	0.228338383741721	0.451840588205062	0.575824878403157	0.575824878403157	0.575824878403157
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Nrn1	ENSMUSG00000039114	0.032663525449452	0.0979905763483559	0.643112334413352	0.643112334413352	0.455625354715449	0.643112334413352
Alg1	ENSMUSG00000039427	0.120545895661628	0.180818843492441	0.00276975149305653	0.00830925447916959	0.299349060054895	0.299349060054895
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Otud3	ENSMUSG00000041161	0.34837756124189	0.593892267963669	0.711854160331342	0.711854160331342	0.395928178642446	0.593892267963669
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Commd10	ENSMUSG00000042705	0.00283103937188883	0.00849311811566649	0.344663224299303	0.516994836448954	0.853801250889739	0.853801250889739
Dpm3	ENSMUSG00000042737	0.0969812105731562	0.290943631719469	0.399548817627028	0.599323226440542	0.92622377157404	0.92622377157404
Mgat2	ENSMUSG00000043998	0.255530331334266	0.576112968612194	0.514934023620345	0.576112968612194	0.576112968612194	0.576112968612194
Nrn1l	ENSMUSG00000044287	0.392614583064079	0.588921874596118	0.706185359872137	0.706185359872137	0.253668577981715	0.588921874596118
B3gntl1	ENSMUSG00000046605	0.0243249029874197	0.0729747089622591	0.578113371816017	0.578113371816017	0.399548817627028	0.578113371816017
Usp14	ENSMUSG00000047879	0.34837756124189	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Fbxl13	ENSMUSG00000048520	0.711240436189781	0.711240436189781	0.514934023620345	0.711240436189781	0.341647690705446	0.711240436189781
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Mettl21d	ENSMUSG00000049882	0.255901190956604	0.383851786434906	0.455625354715448	0.455625354715448	0.0964252305385472	0.289275691615642
Rnf7	ENSMUSG00000051234	0.254414773803597	0.254414773803597	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Rnf181	ENSMUSG00000055850	0.703556284613037	0.703556284613037	0.346527959006435	0.519791938509652	0.341647690705446	0.519791938509652
Commd7	ENSMUSG00000056941	0.0328221470541517	0.098466441162455	0.852175490580835	0.852175490580835	0.576112968612194	0.852175490580835
Tmed9	ENSMUSG00000058569	0.214037080764326	0.519791938509652	0.346527959006435	0.519791938509652	0.577259514257969	0.577259514257969
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
B3gnt9	ENSMUSG00000069920	0.392985378348026	0.450444934184774	0.0947558980989551	0.284267694296865	0.450444934184774	0.450444934184774
Ptrh2	ENSMUSG00000072582	0.00768144932639892	0.0230443479791968	0.346899083932133	0.450444934184774	0.450444934184774	0.450444934184774
Commd6	ENSMUSG00000075486	0.252920381501206	0.379380572251809	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028
Dph1	ENSMUSG00000078789	0.211844580334808	0.317766870502212	0.781170242226513	0.781170242226513	0.17924968721805	0.317766870502212
Eif5a	ENSMUSG00000078812	0.00289311433957183	0.0086793430187155	0.00974037464901008	0.0146105619735151	0.640355507848752	0.640355507848752
Hist3h2a	ENSMUSG00000078851	0.926496242814507	0.926496242814507	0.246478961478169	0.369718442217254	0.147787500009832	0.369718442217254
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951
Rab7	ENSMUSG00000079477	0.642366752097095	0.711034989117171	0.397384062266614	0.711034989117171	0.711034989117171	0.711034989117171
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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RUNX1 regulates transcription of genes involved in differentiation of HSCs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Tcf12	ENSMUSG00000032228	0.0886202385494145	0.132930357824122	0.0886202385494145	0.132930357824122	0.853372965654504	0.853372965654504
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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PTEN Regulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Otud3	ENSMUSG00000041161	0.34837756124189	0.593892267963669	0.711854160331342	0.711854160331342	0.395928178642446	0.593892267963669
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951

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SCF(Skp2)-mediated degradation of p27/p21

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Regulation of PTEN stability and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Otud3	ENSMUSG00000041161	0.34837756124189	0.593892267963669	0.711854160331342	0.711854160331342	0.395928178642446	0.593892267963669
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Mitotic Spindle Checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1

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M Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Emd	ENSMUSG00000001964	0.777922216623952	0.777922216623952	0.178901132102685	0.536703396308054	0.5155648232968	0.7733472349452
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ncaph2	ENSMUSG00000008690	0.01710279005982	0.0513083701794599	0.147458757705094	0.221188136557642	0.255530331334266	0.255530331334266
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Cdca5	ENSMUSG00000024791	0.00768144932639892	0.0115221739895984	0.0012550277248556	0.0037650831745668	0.926333123228344	0.926333123228344
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Ssna1	ENSMUSG00000026966	0.0150443553124285	0.0451330659372853	0.0548979200435556	0.0823468800653334	0.710208797518812	0.710208797518812
Haus2	ENSMUSG00000027285	0.121155015244363	0.363465045733089	0.853480389728993	0.853480389728993	0.300095920620218	0.450143880930327
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Mzt1	ENSMUSG00000033186	0.853372965654504	0.853372965654504	0.643853282854191	0.853372965654504	0.782117202022501	0.853372965654504
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Haus1	ENSMUSG00000041840	0.115037265385284	0.345111796155853	0.450794830295118	0.450794830295118	0.346899083932133	0.450794830295118
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Fgfr1op	ENSMUSG00000069135	0.254787123615605	0.382180685423408	0.642366752097095	0.642366752097095	0.254787123615605	0.382180685423408
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Asymmetric localization of PCP proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Activation of NF-kappaB in B cells

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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G1/S Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Orc1 removal from chromatin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Transcriptional regulation by RUNX2

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cross-presentation of soluble exogenous antigens (endosomes)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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DNA Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Sumo3	ENSMUSG00000020265	0.398108175780842	0.398108175780842	0.246861959455465	0.370292939183197	0.246861959455465	0.370292939183197
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Parg	ENSMUSG00000021911	0.640861491578951	0.853372965654504	0.577259514257969	0.853372965654504	0.853372965654504	0.853372965654504
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
2310003H01Rik	ENSMUSG00000025384	0.347639524025037	0.78180291566155	0.7802108304765	0.78180291566155	0.78180291566155	0.78180291566155
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Ppie	ENSMUSG00000028651	0.213307944885796	0.374861176998506	0.249907451332337	0.374861176998506	0.852065168704833	0.852065168704833
Eya3	ENSMUSG00000028886	0.177853449259986	0.266780173889979	0.171503747555202	0.266780173889979	0.454942951775341	0.454942951775341
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Ppp4c	ENSMUSG00000030697	0.00283103937188883	0.00849311811566649	0.0164739112492867	0.02471086687393	1	1
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Isg15	ENSMUSG00000035692	0.00463747559282086	0.0139124267784626	0.711650020253571	0.711650020253571	0.5155648232968	0.711650020253571
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Nthl1	ENSMUSG00000041429	0.178901132102685	0.268351698154027	0.178901132102684	0.268351698154027	0.7802108304765	0.7802108304765
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Rnf8	ENSMUSG00000090083	0.511742979522636	0.511742979522636	0.345410946355104	0.511742979522636	0.297848640636702	0.511742979522636

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Termination of translesion DNA synthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Isg15	ENSMUSG00000035692	0.00463747559282086	0.0139124267784626	0.711650020253571	0.711650020253571	0.5155648232968	0.711650020253571
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Dual Incision in GG-NER

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Isg15	ENSMUSG00000035692	0.00463747559282086	0.0139124267784626	0.711650020253571	0.711650020253571	0.5155648232968	0.711650020253571
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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G2/M Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Rnf168	ENSMUSG00000014074	0.216214347033995	0.450143880930327	0.300095920620218	0.450143880930327	0.853372965654504	0.853372965654504
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Rnf8	ENSMUSG00000090083	0.511742979522636	0.511742979522636	0.345410946355104	0.511742979522636	0.297848640636702	0.511742979522636

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p53-Dependent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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p53-Dependent G1 DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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TCF dependent signaling in response to WNT

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Pip5k1b	ENSMUSG00000024867	0.400265374208515	0.600398061312773	0.255530331334266	0.600398061312773	0.853480389728993	0.853480389728993
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Klhl12	ENSMUSG00000026455	0.0116356061791785	0.0349068185375355	0.21549027811633	0.323235417174495	0.853372965654504	0.853372965654504
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Rnf43	ENSMUSG00000034177	0.853694531487825	1	1	1	0.34837756124189	1
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Exosc7	ENSMUSG00000025785	0.118409250205154	0.355227750615461	0.456305241393103	0.456305241393103	0.348008842235184	0.456305241393103
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Dis3	ENSMUSG00000033166	0.45596561163947	0.45596561163947	0.120850531362929	0.362551594088788	0.453570536021945	0.45596561163947
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Mitochondrial biogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Gabpa	ENSMUSG00000008976	0.0930846407079411	0.139626961061912	0.0642056836831393	0.139626961061912	0.709375484777034	0.709375484777034
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Sirt4	ENSMUSG00000029524	0.454942951775342	0.578396848531894	0.578396848531894	0.578396848531894	0.577259514257969	0.578396848531894
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739

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Regulation of RAS by GAPs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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G2/M Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Phlda1	ENSMUSG00000020205	0.779238691542963	0.926550375688041	0.708323672944427	0.926550375688041	0.926550375688041	0.926550375688041
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Ssna1	ENSMUSG00000026966	0.0150443553124285	0.0451330659372853	0.0548979200435556	0.0823468800653334	0.710208797518812	0.710208797518812
Haus2	ENSMUSG00000027285	0.121155015244363	0.363465045733089	0.853480389728993	0.853480389728993	0.300095920620218	0.450143880930327
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Cdk11b	ENSMUSG00000029062	0.346527959006435	1	1	1	0.782117202022501	1
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Mzt1	ENSMUSG00000033186	0.853372965654504	0.853372965654504	0.643853282854191	0.853372965654504	0.782117202022501	0.853372965654504
Haus1	ENSMUSG00000041840	0.115037265385284	0.345111796155853	0.450794830295118	0.450794830295118	0.346899083932133	0.450794830295118
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Fgfr1op	ENSMUSG00000069135	0.254787123615605	0.382180685423408	0.642366752097095	0.642366752097095	0.254787123615605	0.382180685423408
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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G1/S DNA Damage Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Transport to the Golgi and subsequent modification

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
B4galt5	ENSMUSG00000017929	0.78148726569172	0.78180291566155	0.638310022345193	0.78180291566155	0.78180291566155	0.78180291566155
Cog1	ENSMUSG00000018661	0.780851835278817	1	1	1	0.514934023620344	1
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Fut8	ENSMUSG00000021065	0.252920381501207	0.588364690595531	0.926550375688041	0.926550375688041	0.392243127063687	0.588364690595531
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Gbf1	ENSMUSG00000025224	0.146141353215796	0.219212029823694	0.0936419271039908	0.219212029823694	1	1
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Arcn1	ENSMUSG00000032096	0.00755778364492933	0.011336675467394	0.00743512899358789	0.011336675467394	0.399548817627028	0.399548817627028
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Mgat2	ENSMUSG00000043998	0.255530331334266	0.576112968612194	0.514934023620345	0.576112968612194	0.576112968612194	0.576112968612194
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Tmed9	ENSMUSG00000058569	0.214037080764326	0.519791938509652	0.346527959006435	0.519791938509652	0.577259514257969	0.577259514257969
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951

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RNA polymerase II transcribes snRNA genes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ell2	ENSMUSG00000001542	0.0766111619812296	0.229833485943689	0.346899083932133	0.520348625898199	0.926333123228344	0.926333123228344
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Cpsf3l	ENSMUSG00000029034	0.146800541856249	0.400265374208515	0.400265374208515	0.400265374208515	0.348008842235184	0.400265374208515
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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Mitotic G2-G2/M phases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Phlda1	ENSMUSG00000020205	0.779238691542963	0.926550375688041	0.708323672944427	0.926550375688041	0.926550375688041	0.926550375688041
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Pkmyt1	ENSMUSG00000023908	0.0964252305385474	0.289275691615642	0.341647690705446	0.512471536058169	0.776919261684345	0.776919261684345
Ssna1	ENSMUSG00000026966	0.0150443553124285	0.0451330659372853	0.0548979200435556	0.0823468800653334	0.710208797518812	0.710208797518812
Haus2	ENSMUSG00000027285	0.121155015244363	0.363465045733089	0.853480389728993	0.853480389728993	0.300095920620218	0.450143880930327
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Cdk11b	ENSMUSG00000029062	0.346527959006435	1	1	1	0.782117202022501	1
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Mzt1	ENSMUSG00000033186	0.853372965654504	0.853372965654504	0.643853282854191	0.853372965654504	0.782117202022501	0.853372965654504
Haus1	ENSMUSG00000041840	0.115037265385284	0.345111796155853	0.450794830295118	0.450794830295118	0.346899083932133	0.450794830295118
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Fgfr1op	ENSMUSG00000069135	0.254787123615605	0.382180685423408	0.642366752097095	0.642366752097095	0.254787123615605	0.382180685423408
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Formation of ATP by chemiosmotic coupling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739

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Translesion Synthesis by POLH

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Cristae formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp5g1	ENSMUSG00000006057	0.146800541856249	0.220200812784373	0.0150443553124285	0.0451330659372854	1	1
Atp5j	ENSMUSG00000022890	0.508488713161374	0.513026869856283	0.00115309164684955	0.00345927494054866	0.513026869856283	0.513026869856283
Atp5o	ENSMUSG00000022956	0.848399006995053	0.848399006995053	0.846088894509579	0.848399006995053	0.634645058916812	0.848399006995053
Atp5j2	ENSMUSG00000038690	0.205174703261494	0.307762054892242	0.116265430850263	0.307762054892242	0.5155648232968	0.5155648232968
Atp5l	ENSMUSG00000038717	0.142165951159432	0.213248926739148	0.0527343611033823	0.158203083310147	0.92589277149125	0.92589277149125
Atp5k	ENSMUSG00000050856	0.177153312234059	0.265729968351089	0.0110666956860337	0.0332000870581011	0.853801250889739	0.853801250889739

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APC/C:Cdc20 mediated degradation of Cyclin B

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Asparagine N-linked glycosylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Man1a2	ENSMUSG00000008763	0.395196379647461	0.758757567042777	0.505838378028518	0.758757567042777	1	1
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
B4galt5	ENSMUSG00000017929	0.78148726569172	0.78180291566155	0.638310022345193	0.78180291566155	0.78180291566155	0.78180291566155
Cog1	ENSMUSG00000018661	0.780851835278817	1	1	1	0.514934023620344	1
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Fut8	ENSMUSG00000021065	0.252920381501207	0.588364690595531	0.926550375688041	0.926550375688041	0.392243127063687	0.588364690595531
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Tsta3	ENSMUSG00000022570	0.254414773803597	0.763244321410791	0.5155648232968	0.7733472349452	1	1
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Gbf1	ENSMUSG00000025224	0.146141353215796	0.219212029823694	0.0936419271039908	0.219212029823694	1	1
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Dpm2	ENSMUSG00000026810	0.0230207752632622	0.0345311628948933	0.00400309634280189	0.0120092890284057	0.575536202757516	0.575536202757516
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Arcn1	ENSMUSG00000032096	0.00755778364492933	0.011336675467394	0.00743512899358789	0.011336675467394	0.399548817627028	0.399548817627028
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Nagk	ENSMUSG00000034744	0.00153425095635555	0.00460275286906664	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571
Alg1	ENSMUSG00000039427	0.120545895661628	0.180818843492441	0.00276975149305653	0.00830925447916959	0.299349060054895	0.299349060054895
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Dpm3	ENSMUSG00000042737	0.0969812105731562	0.290943631719469	0.399548817627028	0.599323226440542	0.92622377157404	0.92622377157404
Mgat2	ENSMUSG00000043998	0.255530331334266	0.576112968612194	0.514934023620345	0.576112968612194	0.576112968612194	0.576112968612194
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Tmed9	ENSMUSG00000058569	0.214037080764326	0.519791938509652	0.346527959006435	0.519791938509652	0.577259514257969	0.577259514257969
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951

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PCP/CE pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ap2s1	ENSMUSG00000008036	0.0328221470541517	0.0492332205812275	0.0232795908282423	0.0492332205812275	0.293293089483362	0.293293089483362
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Ap2m1	ENSMUSG00000022841	0.513665062682276	0.513665062682276	0.17433930265919	0.513665062682276	0.508488713161374	0.513665062682276
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Gap-filling DNA repair synthesis and ligation in GG-NER

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Cyclin E associated events during G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Beta-catenin independent WNT signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ap2s1	ENSMUSG00000008036	0.0328221470541517	0.0492332205812275	0.0232795908282423	0.0492332205812275	0.293293089483362	0.293293089483362
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Ap2m1	ENSMUSG00000022841	0.513665062682276	0.513665062682276	0.17433930265919	0.513665062682276	0.508488713161374	0.513665062682276
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Gng12	ENSMUSG00000036402	0.853372965654504	0.853372965654504	0.0761127945805735	0.228338383741721	0.398829756175299	0.598244634262948
Gngt2	ENSMUSG00000038811	0.178901132102685	0.536703396308054	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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APC-Cdc20 mediated degradation of Nek2A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Anapc16	ENSMUSG00000020107	0.0417377002086289	0.125213100625887	0.17610058307789	0.264150874616835	1	1
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Ub-specific processing proteases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Fkbp8	ENSMUSG00000019428	0.0334587898203823	0.100376369461147	0.216214347033995	0.324321520550992	0.926658283600152	0.926658283600152
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ripk1	ENSMUSG00000021408	0.577829325134931	0.782117202022501	0.044737329683373	0.134211989050119	0.782117202022501	0.782117202022501
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Usp25	ENSMUSG00000022867	0.578113371816017	0.853801250889739	0.300095920620218	0.853801250889739	0.853801250889739	0.853801250889739
Ifih1	ENSMUSG00000026896	0.778911768167544	0.778911768167544	0.00477055016690543	0.0143116505007163	0.709375484777034	0.778911768167544
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Usp3	ENSMUSG00000032376	0.0761127945805735	0.145471815859734	0.0969812105731561	0.145471815859734	0.399548817627028	0.399548817627028
Usp14	ENSMUSG00000047879	0.34837756124189	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ptrh2	ENSMUSG00000072582	0.00768144932639892	0.0230443479791968	0.346899083932133	0.450444934184774	0.450444934184774	0.450444934184774
Hist3h2a	ENSMUSG00000078851	0.926496242814507	0.926496242814507	0.246478961478169	0.369718442217254	0.147787500009832	0.369718442217254
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Global Genome Nucleotide Excision Repair (GG-NER)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Sumo3	ENSMUSG00000020265	0.398108175780842	0.398108175780842	0.246861959455465	0.370292939183197	0.246861959455465	0.370292939183197
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Cops7b	ENSMUSG00000026240	0.0447373296833729	0.134211989050119	0.345037391052888	0.345037391052888	0.254414773803597	0.345037391052888
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cops8	ENSMUSG00000034432	0.00481536616919075	0.0144460985075723	0.0763619660358786	0.114542949053818	0.120545895661628	0.120545895661628
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Antigen processing: Ubiquitination & Proteasome degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fbxo7	ENSMUSG00000001786	0.173632433887832	0.367990297261757	0.245326864841171	0.367990297261757	0.92622377157404	0.92622377157404
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Fbxw9	ENSMUSG00000008167	0.509798138101151	0.764697207151727	0.0763619660358786	0.229085898107636	0.7802108304765	0.7802108304765
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Cbll1	ENSMUSG00000020659	0.447621891168214	0.638824656785692	0.638824656785692	0.638824656785692	0.174692232033629	0.524076696100887
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rnf115	ENSMUSG00000028098	0.578113371816017	0.578113371816017	0.255901190956604	0.578113371816017	0.578113371816017	0.578113371816017
Ube2j1	ENSMUSG00000028277	0.711240436189781	0.926658283600152	0.926658283600152	0.926658283600152	0.0166824765447319	0.0500474296341958
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Fbxo17	ENSMUSG00000030598	0.0805126803503835	0.120769020525575	0.0239310464924689	0.0717931394774068	0.635966700067775	0.635966700067775
Asb11	ENSMUSG00000031382	1	1	0.400265374208515	0.865460619345501	0.576973746230334	0.865460619345501
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ube2q2	ENSMUSG00000032307	0.398108175780842	0.770497594023414	0.853372965654504	0.853372965654504	0.513665062682276	0.770497594023414
Ube2cbp	ENSMUSG00000032415	0.399548817627028	0.576973746230334	0.120850531362929	0.362551594088788	0.576973746230334	0.576973746230334
Anapc13	ENSMUSG00000035048	0.578113371816017	0.643359829732651	0.00159435459956481	0.00478306379869443	0.643359829732651	0.643359829732651
Siah1a	ENSMUSG00000036840	0.252545530864481	0.507888175712984	0.338592117141989	0.507888175712984	0.7802108304765	0.7802108304765
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Vprbp	ENSMUSG00000040325	0.177853449259986	0.533560347779958	0.398829756175299	0.598244634262948	0.853801250889739	0.853801250889739
Trim41	ENSMUSG00000040365	0.853801250889739	1	0.119631084167592	0.358893252502775	1	1
Fbxl13	ENSMUSG00000048520	0.711240436189781	0.711240436189781	0.514934023620345	0.711240436189781	0.341647690705446	0.711240436189781
Rnf7	ENSMUSG00000051234	0.254414773803597	0.254414773803597	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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CLEC7A (Dectin-1) signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Pycard	ENSMUSG00000030793	0.0117179415987427	0.0351538247962282	0.577829325134931	0.577829325134931	0.577829325134931	0.577829325134931
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Cyclin A:Cdk2-associated events at S phase entry

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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COPII-mediated vesicle transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951

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Alpha-defensins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
AY761184	ENSMUSG00000058618	0.513665062682276	0.513665062682276	0.113190884633071	0.339572653899213	0.347639524025037	0.513665062682276
Gm14851	ENSMUSG00000061958	0.779888212132595	0.779888212132595	0.395196379647461	0.779888212132595	0.643359829732651	0.779888212132595
Defa24	ENSMUSG00000064213	0.299349060054895	0.400265374208515	0.144157978128026	0.400265374208515	0.400265374208515	0.400265374208515
Gm14850	ENSMUSG00000065956	0.345037391052887	0.577259514257969	0.576973746230334	0.577259514257969	0.577259514257969	0.577259514257969
Defa3	ENSMUSG00000074440	0.710001140920767	0.710001140920767	0.0334587898203824	0.100376369461147	0.345037391052887	0.517556086579331
Gm15284	ENSMUSG00000074444	0.576973746230334	0.578113371816017	0.177853449259986	0.533560347779958	0.578113371816017	0.578113371816017
Defa23	ENSMUSG00000074446	0.707899741868332	0.707899741868332	0.00376384688812124	0.0112915406643637	0.254414773803597	0.381622160705395
Gm15293	ENSMUSG00000079116	0.453570536021945	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Glutathione conjugation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mgst1	ENSMUSG00000008540	0.0969812105731562	0.290943631719469	0.514934023620345	0.711034989117171	0.711034989117171	0.711034989117171
Esd	ENSMUSG00000021996	0.300095920620218	0.450143880930327	0.252545530864481	0.450143880930327	0.853694531487825	0.853694531487825
Gsto2	ENSMUSG00000025069	0.254041925545275	0.762125776635824	0.779726369441083	0.779726369441083	0.514617706526787	0.77192655979018
Gsta3	ENSMUSG00000025934	0.781170242226513	0.781170242226513	0.347639524025037	0.781170242226513	0.710208797518812	0.781170242226513
Gclc	ENSMUSG00000032350	0.0115535350288052	0.0346606050864156	0.115037265385284	0.172555898077926	0.455625354715449	0.455625354715449
Gstt2	ENSMUSG00000033318	0.144820068500794	0.382180685423408	0.254787123615605	0.382180685423408	0.575824878403157	0.575824878403157
Ggt6	ENSMUSG00000040471	0.0113089139751576	0.0339267419254727	0.0947558980989551	0.142133847148433	0.711240436189781	0.711240436189781
Mgst2	ENSMUSG00000074604	0.567513221841557	0.63250023504486	0.63250023504486	0.63250023504486	0.146141353215796	0.438424059647387

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Downstream signaling events of B Cell Receptor (BCR)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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ER to Golgi Anterograde Transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Folr1	ENSMUSG00000001827	0.148115998140416	0.200650219614881	0.200650219614881	0.200650219614881	0.0763619660358786	0.200650219614881
Gosr1	ENSMUSG00000010392	0.0230207752632622	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.148115998140415	0.148115998140415
Trappc2l	ENSMUSG00000015013	0.348008842235184	0.522013263352777	0.0162664168407233	0.0487992505221699	0.710416009055326	0.710416009055326
Cog1	ENSMUSG00000018661	0.780851835278817	1	1	1	0.514934023620344	1
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Actr10	ENSMUSG00000021076	0.0211129141819613	0.063338742545884	0.371967876858695	0.557951815288042	1	1
Tfg	ENSMUSG00000022757	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344	0.781170242226513	0.926333123228344
Mcfd2	ENSMUSG00000024150	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651
Cnih2	ENSMUSG00000024873	0.853801250889739	0.853801250889739	0.346527959006435	0.853801250889739	0.643359829732651	0.853801250889739
Gbf1	ENSMUSG00000025224	0.146141353215796	0.219212029823694	0.0936419271039908	0.219212029823694	1	1
Bet1l	ENSMUSG00000025484	0.0116356061791785	0.0349068185375355	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Dctn3	ENSMUSG00000028447	0.00468160475316411	0.00702240712974616	0.00253244992826164	0.00702240712974616	0.926550375688041	0.926550375688041
Trappc3	ENSMUSG00000028847	0.0222505050945548	0.0667515152836643	0.0674166595311035	0.101124989296655	0.781170242226513	0.781170242226513
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Arcn1	ENSMUSG00000032096	0.00755778364492933	0.011336675467394	0.00743512899358789	0.011336675467394	0.399548817627028	0.399548817627028
Trappc4	ENSMUSG00000032112	0.00649065913668484	0.0194719774100545	0.0886202385494145	0.132930357824122	0.926550375688041	0.926550375688041
Lman1	ENSMUSG00000041891	0.146141353215795	0.438424059647386	0.640355507848752	0.960533261773128	1	1
Trappc1	ENSMUSG00000049299	0.509144723230069	0.509144723230069	0.329176790045262	0.509144723230069	0.509144723230069	0.509144723230069
Tmed9	ENSMUSG00000058569	0.214037080764326	0.519791938509652	0.346527959006435	0.519791938509652	0.577259514257969	0.577259514257969
Trappc2	ENSMUSG00000079317	0.453570536021945	0.640861491578951	0.216214347033995	0.640861491578951	0.640861491578951	0.640861491578951

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Class I MHC mediated antigen processing & presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fbxo7	ENSMUSG00000001786	0.173632433887832	0.367990297261757	0.245326864841171	0.367990297261757	0.92622377157404	0.92622377157404
Bcap31	ENSMUSG00000002015	0.772410589885492	0.924286968561133	0.924286968561133	0.924286968561133	0.338592117141989	0.924286968561133
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Fbxw9	ENSMUSG00000008167	0.509798138101151	0.764697207151727	0.0763619660358786	0.229085898107636	0.7802108304765	0.7802108304765
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Sar1b	ENSMUSG00000020386	0.852832278580641	0.852832278580641	0.707899741868332	0.852832278580641	0.577829325134931	0.852832278580641
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Cbll1	ENSMUSG00000020659	0.447621891168214	0.638824656785692	0.638824656785692	0.638824656785692	0.174692232033629	0.524076696100887
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Rnf115	ENSMUSG00000028098	0.578113371816017	0.578113371816017	0.255901190956604	0.578113371816017	0.578113371816017	0.578113371816017
Ube2j1	ENSMUSG00000028277	0.711240436189781	0.926658283600152	0.926658283600152	0.926658283600152	0.0166824765447319	0.0500474296341958
Vamp3	ENSMUSG00000028955	0.850721744111585	0.852940894477647	0.852940894477647	0.852940894477647	0.711034989117171	0.852940894477647
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Anapc5	ENSMUSG00000029472	0.11595859961889	0.173937899428335	0.094755898098955	0.173937899428335	0.395196379647461	0.395196379647461
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Fbxo17	ENSMUSG00000030598	0.0805126803503835	0.120769020525575	0.0239310464924689	0.0717931394774068	0.635966700067775	0.635966700067775
Asb11	ENSMUSG00000031382	1	1	0.400265374208515	0.865460619345501	0.576973746230334	0.865460619345501
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ube2q2	ENSMUSG00000032307	0.398108175780842	0.770497594023414	0.853372965654504	0.853372965654504	0.513665062682276	0.770497594023414
Ube2cbp	ENSMUSG00000032415	0.399548817627028	0.576973746230334	0.120850531362929	0.362551594088788	0.576973746230334	0.576973746230334
Anapc13	ENSMUSG00000035048	0.578113371816017	0.643359829732651	0.00159435459956481	0.00478306379869443	0.643359829732651	0.643359829732651
Siah1a	ENSMUSG00000036840	0.252545530864481	0.507888175712984	0.338592117141989	0.507888175712984	0.7802108304765	0.7802108304765
Cdc16	ENSMUSG00000038416	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.0447373296833729	0.134211989050119
Vprbp	ENSMUSG00000040325	0.177853449259986	0.533560347779958	0.398829756175299	0.598244634262948	0.853801250889739	0.853801250889739
Trim41	ENSMUSG00000040365	0.853801250889739	1	0.119631084167592	0.358893252502775	1	1
Fbxl13	ENSMUSG00000048520	0.711240436189781	0.711240436189781	0.514934023620345	0.711240436189781	0.341647690705446	0.711240436189781
Rnf7	ENSMUSG00000051234	0.254414773803597	0.254414773803597	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
H2-T22	ENSMUSG00000056116	5.02570344982353e-05	0.000150771103494706	0.0592616003460512	0.0888924005190768	0.255530331334266	0.255530331334266
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993

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The role of GTSE1 in G2/M progression after G2 checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Postmitotic nuclear pore complex (NPC) reformation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Rcc1	ENSMUSG00000028896	0.0116356061791785	0.0349068185375355	0.567818482366294	0.567818482366294	0.447621891168214	0.567818482366294
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045

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UCH proteinases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Nedd8	ENSMUSG00000010376	0.0852666932085725	0.255800079625717	0.297095062262362	0.445642593393544	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Hist3h2a	ENSMUSG00000078851	0.926496242814507	0.926496242814507	0.246478961478169	0.369718442217254	0.147787500009832	0.369718442217254
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Translesion synthesis by POLI

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Translesion synthesis by REV1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Processing of Capped Intronless Pre-mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1

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Signaling by WNT

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ap2s1	ENSMUSG00000008036	0.0328221470541517	0.0492332205812275	0.0232795908282423	0.0492332205812275	0.293293089483362	0.293293089483362
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Ap2m1	ENSMUSG00000022841	0.513665062682276	0.513665062682276	0.17433930265919	0.513665062682276	0.508488713161374	0.513665062682276
Csnk1a1	ENSMUSG00000024576	0.300095920620218	0.300095920620218	0.255530331334266	0.300095920620218	0.295581119060361	0.300095920620218
Camk2a	ENSMUSG00000024617	0.926658283600152	0.926658283600152	0.511742979522636	0.767614469283954	0.45596561163947	0.767614469283954
Pip5k1b	ENSMUSG00000024867	0.400265374208515	0.600398061312773	0.255530331334266	0.600398061312773	0.853480389728993	0.853480389728993
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Klhl12	ENSMUSG00000026455	0.0116356061791785	0.0349068185375355	0.21549027811633	0.323235417174495	0.853372965654504	0.853372965654504
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Ctbp2	ENSMUSG00000030970	0.853480389728993	0.926550375688041	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Rnf43	ENSMUSG00000034177	0.853694531487825	1	1	1	0.34837756124189	1
Gng12	ENSMUSG00000036402	0.853372965654504	0.853372965654504	0.0761127945805735	0.228338383741721	0.398829756175299	0.598244634262948
Gngt2	ENSMUSG00000038811	0.178901132102685	0.536703396308054	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Amplification of signal from the kinetochores

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1

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Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Ndel1	ENSMUSG00000018736	0.449391287230099	0.780851835278818	0.780851835278818	0.780851835278818	0.638824656785692	0.780851835278818
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Pafah1b1	ENSMUSG00000020745	0.0166824765447319	0.0500474296341958	0.92589277149125	0.92589277149125	0.850151080737202	0.92589277149125
Ppp2r5e	ENSMUSG00000021051	0.392243127063687	0.764697207151727	0.853907737111068	0.853907737111068	0.509798138101151	0.764697207151727
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Gm9846	ENSMUSG00000050621	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	1	1

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DNA Damage Bypass

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rchy1	ENSMUSG00000029397	0.0230207752632622	0.0345311628948933	0.0171027900598199	0.0345311628948933	0.57466664340579	0.57466664340579
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Isg15	ENSMUSG00000035692	0.00463747559282086	0.0139124267784626	0.711650020253571	0.711650020253571	0.5155648232968	0.711650020253571
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Deubiquitination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Cdc20	ENSMUSG00000006398	0.00270924971713393	0.0081277491514018	0.0171027900598199	0.0256541850897299	0.853694531487825	0.853694531487825
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Nedd8	ENSMUSG00000010376	0.0852666932085725	0.255800079625717	0.297095062262362	0.445642593393544	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Fkbp8	ENSMUSG00000019428	0.0334587898203823	0.100376369461147	0.216214347033995	0.324321520550992	0.926658283600152	0.926658283600152
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ripk1	ENSMUSG00000021408	0.577829325134931	0.782117202022501	0.044737329683373	0.134211989050119	0.782117202022501	0.782117202022501
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Usp25	ENSMUSG00000022867	0.578113371816017	0.853801250889739	0.300095920620218	0.853801250889739	0.853801250889739	0.853801250889739
Ifih1	ENSMUSG00000026896	0.778911768167544	0.778911768167544	0.00477055016690543	0.0143116505007163	0.709375484777034	0.778911768167544
Usp8	ENSMUSG00000027363	0.642366752097095	0.642366752097095	0.286303237509397	0.429454856264095	0.254414773803597	0.429454856264095
Rad23b	ENSMUSG00000028426	0.578396848531894	0.867595272797842	0.178901132102685	0.536703396308054	0.926550375688041	0.926550375688041
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Usp10	ENSMUSG00000031826	0.249528554620971	0.374292831931456	0.853694531487825	0.853694531487825	0.179249687218049	0.374292831931456
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Usp3	ENSMUSG00000032376	0.0761127945805735	0.145471815859734	0.0969812105731561	0.145471815859734	0.399548817627028	0.399548817627028
Otud3	ENSMUSG00000041161	0.34837756124189	0.593892267963669	0.711854160331342	0.711854160331342	0.395928178642446	0.593892267963669
Usp14	ENSMUSG00000047879	0.34837756124189	0.853801250889739	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Ptrh2	ENSMUSG00000072582	0.00768144932639892	0.0230443479791968	0.346899083932133	0.450444934184774	0.450444934184774	0.450444934184774
Hist3h2a	ENSMUSG00000078851	0.926496242814507	0.926496242814507	0.246478961478169	0.369718442217254	0.147787500009832	0.369718442217254
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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B-WICH complex positively regulates rRNA expression

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Positive epigenetic regulation of rRNA expression

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Znrd1	ENSMUSG00000036315	0.0583853430099096	0.108941434476471	0.072627622984314	0.108941434476471	0.92589277149125	0.92589277149125
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Translesion synthesis by POLK

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Generic Transcription Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gtf2h4	ENSMUSG00000001524	0.0158546704257247	0.023782005638587	0.00276975149305653	0.0083092544791696	0.926003599371282	0.926003599371282
Tead3	ENSMUSG00000002249	0.18064054691103	0.449023590082343	0.299349060054895	0.449023590082343	0.782117202022501	0.782117202022501
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Lbr	ENSMUSG00000004880	0.0007950941817707	0.0023852825453121	0.341647690705446	0.512471536058169	0.643853282854191	0.643853282854191
Prdx2	ENSMUSG00000005161	0.0553321944628786	0.0829982916943178	0.0306217702495172	0.0829982916943178	0.17924968721805	0.17924968721805
Ctcf	ENSMUSG00000005698	0.399548817627028	0.599323226440542	0.254414773803597	0.599323226440542	0.711650020253571	0.711650020253571
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Ttc5	ENSMUSG00000006288	0.299349060054895	0.575536202757516	0.397384062266614	0.575536202757516	0.575536202757516	0.575536202757516
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Ccnt1	ENSMUSG00000011960	0.170434860179341	0.255652290269012	0.0583853430099097	0.175156029029729	0.643359829732651	0.643359829732651
Nelfcd	ENSMUSG00000016253	0.0579478375430677	0.0869217563146015	0.0312459040565944	0.0869217563146015	0.57466664340579	0.57466664340579
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Cox7c	ENSMUSG00000017778	0.923073872182818	0.923073872182818	0.491192352323594	0.736788528485392	0.338592117141989	0.736788528485392
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Zkscan6	ENSMUSG00000018347	0.00276975149305653	0.00830925447916959	0.575824878403157	0.711034989117171	0.711034989117171	0.711034989117171
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Esr1	ENSMUSG00000019768	0.711854160331342	0.711854160331342	0.141500034183268	0.424500102549803	0.341647690705446	0.512471536058169
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Supt4a	ENSMUSG00000020485	0.0969812105731562	0.175777610154895	0.117185073436597	0.175777610154895	0.711034989117171	0.711034989117171
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Gtf2h2	ENSMUSG00000021639	0.78180291566155	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Hdac7	ENSMUSG00000022475	0.072378961026407	0.217136883079221	0.450794830295118	0.450794830295118	0.337435786255284	0.450794830295118
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Cox14	ENSMUSG00000023020	0.443306001726868	0.443306001726868	0.108864301062964	0.26625532344024	0.17750354896016	0.26625532344024
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Tcf7l2	ENSMUSG00000024985	0.851954599472143	0.853801250889739	0.0236697127745139	0.0710091383235417	0.853801250889739	0.853801250889739
Atrip	ENSMUSG00000025646	0.0171027900598199	0.0256541850897299	0.0116356061791785	0.0256541850897299	0.299349060054895	0.299349060054895
Taf3	ENSMUSG00000025782	0.514934023620345	0.642366752097095	0.5155648232968	0.642366752097095	0.642366752097095	0.642366752097095
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ctsk	ENSMUSG00000028111	0.148115998140416	0.323235417174496	0.21549027811633	0.323235417174496	0.513665062682276	0.513665062682276
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Rheb	ENSMUSG00000028945	0.92622377157404	0.92622377157404	0.0441715176243983	0.132514552873195	0.711854160331342	0.92622377157404
Cdk5	ENSMUSG00000028969	0.0575107614292585	0.0882349010820225	0.058823267388015	0.0882349010820225	0.255901190956604	0.255901190956604
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Triap1	ENSMUSG00000029535	0.00147557935671113	0.0044267380701334	0.378414240914692	0.567621361372039	0.63250023504486	0.63250023504486
Ndufa4	ENSMUSG00000029632	0.0544641512383265	0.16339245371498	0.208897379073412	0.313346068610118	0.710416009055326	0.710416009055326
Auts2	ENSMUSG00000029673	0.11993617140438	0.359808514213139	0.254787123615605	0.382180685423408	0.455625354715448	0.455625354715448
Zkscan1	ENSMUSG00000029729	0.0756145297453648	0.113421794618047	0.0756145297453648	0.113421794618047	0.400265374208515	0.400265374208515
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Pin1	ENSMUSG00000032171	0.0328221470541517	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.575824878403157	0.575824878403157
Tcf12	ENSMUSG00000032228	0.0886202385494145	0.132930357824122	0.0886202385494145	0.132930357824122	0.853372965654504	0.853372965654504
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Gtf2h5	ENSMUSG00000034345	0.501782052576058	0.501782052576058	0.0605199207515257	0.181559762254577	0.342026805366747	0.501782052576058
Cnot3	ENSMUSG00000035632	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017	0.578113371816017
Kctd1	ENSMUSG00000036225	0.344663224299303	0.521459286037555	0.78180291566155	0.78180291566155	0.347639524025037	0.521459286037555
Cox6b1	ENSMUSG00000036751	0.208897379073412	0.313346068610118	0.0432318933800775	0.129695680140232	0.853907737111068	0.853907737111068
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Cnot4	ENSMUSG00000038784	0.144820068500793	0.43446020550238	0.300095920620218	0.450143880930327	0.575824878403157	0.575824878403157
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Zfp750	ENSMUSG00000039238	0.053382016116041	0.0813711899786324	0.241452668344062	0.241452668344062	0.0542474599857549	0.0813711899786324
Cox19	ENSMUSG00000045438	0.392985378348026	0.589478067522039	0.780851835278818	0.780851835278818	0.180293335960318	0.540880007880955
Zfp560	ENSMUSG00000045519	0.00159435459956481	0.00478306379869442	0.148115998140416	0.148115998140416	0.0334587898203823	0.0501881847305735
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Taf13	ENSMUSG00000048100	0.926658283600152	0.926658283600152	0.0443599545252852	0.133079863575856	0.926550375688041	0.926658283600152
Lamtor4	ENSMUSG00000050552	0.0947558980989551	0.142133847148433	0.0451153644990945	0.135346093497283	0.711650020253571	0.711650020253571
Zfp212	ENSMUSG00000052763	0.00468160475316412	0.0140448142594924	0.0763619660358787	0.114542949053818	0.853372965654504	0.853372965654504
Zfp472	ENSMUSG00000053600	0.511742979522636	0.860248370921054	0.573498913947369	0.860248370921054	0.92622377157404	0.92622377157404
Zkscan5	ENSMUSG00000055991	0.45596561163947	0.45596561163947	0.0113901882503033	0.0341705647509098	0.0232795908282423	0.0349193862423634
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Zfp945	ENSMUSG00000059142	0.246861959455465	0.740585878366394	0.853480389728993	0.853480389728993	0.782117202022501	0.853480389728993
Mamld1	ENSMUSG00000059401	0.0113089139751575	0.0339267419254726	0.45596561163947	0.683948417459205	0.926003599371282	0.926003599371282
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Brpf3	ENSMUSG00000063952	0.782117202022501	0.782117202022501	0.00450646370870541	0.0135193911261162	0.505169133438821	0.757753700158231
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544
Tceb1	ENSMUSG00000079658	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693	0.853480389728993	0.853480389728993
Lamtor5	ENSMUSG00000087260	0.640861491578951	0.640861491578951	0.347639524025037	0.640861491578951	0.577259514257969	0.640861491578951
Cox16	ENSMUSG00000091803	0.776919261684345	0.776919261684345	0.575536202757516	0.776919261684345	0.513665062682276	0.776919261684345

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Oxidative Stress Induced Senescence

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Eed	ENSMUSG00000030619	0.146800541856249	0.346899083932133	0.346899083932133	0.346899083932133	0.252545530864481	0.346899083932133
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Map2k4	ENSMUSG00000033352	0.777922216623952	0.777922216623952	0.0953125666339397	0.285937699901819	0.398108175780842	0.597162263671263
Jun	ENSMUSG00000052684	0.0241933715424143	0.0725801146272428	0.853907737111068	0.853907737111068	0.299349060054895	0.449023590082343
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155

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Mitotic G1 phase and G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Gmnn	ENSMUSG00000006715	0.0701431284016184	0.178072395122005	0.118714930081337	0.178072395122005	0.695706182905486	0.695706182905486
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Mcm10	ENSMUSG00000026669	0.0953125666339397	0.285937699901819	0.291756209988535	0.398108175780842	0.398108175780842	0.398108175780842
Orc5	ENSMUSG00000029012	0.453570536021945	0.680355804032917	0.926658283600152	0.926658283600152	0.450444934184774	0.680355804032917
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Ppp2r1b	ENSMUSG00000032058	0.209636747299872	0.392985378348026	0.392985378348026	0.392985378348026	0.299349060054895	0.392985378348026
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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RAB geranylgeranylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rab8a	ENSMUSG00000003037	0.148115998140416	0.323235417174495	0.21549027811633	0.323235417174495	0.926003599371282	0.926003599371282
Rab11a	ENSMUSG00000004771	0.147458757705094	0.442376273115283	0.455625354715448	0.455625354715448	0.346527959006434	0.455625354715448
Rab25	ENSMUSG00000008601	0.513665062682276	0.853049270252403	0.78148726569172	0.853049270252403	0.853049270252403	0.853049270252403
Rab5a	ENSMUSG00000017831	0.256271555563966	0.299349060054895	0.255901190956604	0.299349060054895	0.299349060054895	0.299349060054895
Rab5c	ENSMUSG00000019173	0.398108175780842	1	1	1	0.926658283600152	1
Ptp4a2	ENSMUSG00000028788	0.711650020253571	0.926441990075769	0.398829756175299	0.926441990075769	0.926441990075769	0.926441990075769
Rab6a	ENSMUSG00000030704	0.0097403746490101	0.0292211239470303	0.091411676944639	0.137117515416958	0.92622377157404	0.92622377157404
Rab39b	ENSMUSG00000031202	0.712057867818062	0.853801250889739	0.454600801949285	0.853801250889739	0.853801250889739	0.853801250889739
Rabggtb	ENSMUSG00000038975	0.254787123615605	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Rab7	ENSMUSG00000079477	0.642366752097095	0.711034989117171	0.397384062266614	0.711034989117171	0.711034989117171	0.711034989117171

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Nucleosome assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Mis18a	ENSMUSG00000022978	0.348008842235184	0.522013263352776	0.344663224299303	0.522013263352776	0.853694531487825	0.853694531487825
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Rsf1	ENSMUSG00000035623	0.0964252305385472	0.144637845807821	0.0763619660358786	0.144637845807821	0.575536202757516	0.575536202757516
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Cenpw	ENSMUSG00000075266	0.255530331334266	0.383851786434906	0.255901190956604	0.383851786434906	0.514934023620345	0.514934023620345

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Deposition of new CENPA-containing nucleosomes at the centromere

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Mis18a	ENSMUSG00000022978	0.348008842235184	0.522013263352776	0.344663224299303	0.522013263352776	0.853694531487825	0.853694531487825
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Rsf1	ENSMUSG00000035623	0.0964252305385472	0.144637845807821	0.0763619660358786	0.144637845807821	0.575536202757516	0.575536202757516
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Cenpw	ENSMUSG00000075266	0.255530331334266	0.383851786434906	0.255901190956604	0.383851786434906	0.514934023620345	0.514934023620345

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Activation, translocation and oligomerization of BAX

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bax	ENSMUSG00000003873	0.0150443553124284	0.0451330659372853	0.0703913497478892	0.105587024621834	0.710001140920767	0.710001140920767
Bid	ENSMUSG00000004446	0.299349060054895	0.449023590082343	0.92589277149125	0.92589277149125	0.253294730253594	0.449023590082343

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RNA Polymerase II Transcription Termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddx39	ENSMUSG00000005481	0.0236697127745139	0.0710091383235416	0.640861491578951	0.640861491578951	0.640355507848752	0.640861491578951
Srsf6	ENSMUSG00000016921	0.711854160331342	1	1	1	0.853372965654504	1
Papola	ENSMUSG00000021111	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972	0.926658283600152	0.926658283600152
Pabpn1	ENSMUSG00000022194	0.708534948098331	0.708534948098331	0.455625354715449	0.708534948098331	0.511742979522636	0.708534948098331
Clp1	ENSMUSG00000027079	0.0880615565264046	0.264184669579214	0.177153312234059	0.265729968351089	1	1
Magoh	ENSMUSG00000028609	0.635703516568382	0.924872384323463	0.704220158648919	0.924872384323463	0.924872384323463	0.924872384323463
Fip1l1	ENSMUSG00000029227	0.252920381501207	0.643853282854191	0.5155648232968	0.643853282854191	0.643853282854191	0.643853282854191
Cpsf4	ENSMUSG00000029625	0.0015541259555958	0.0046623778667874	0.454942951775341	0.682414427663012	1	1
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Srsf3	ENSMUSG00000071172	0.513665062682276	0.778911768167544	0.577259514257969	0.778911768167544	0.778911768167544	0.778911768167544
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1

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E3 ubiquitin ligases ubiquitinate target proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Wac	ENSMUSG00000024283	0.119631084167592	0.324321520550992	0.216214347033995	0.324321520550992	0.514934023620344	0.514934023620344
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Rnf181	ENSMUSG00000055850	0.703556284613037	0.703556284613037	0.346527959006435	0.519791938509652	0.341647690705446	0.519791938509652
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544

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Metabolism of non-coding RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Gemin2	ENSMUSG00000060121	0.180293335960318	0.383295497001398	0.450444934184774	0.450444934184774	0.255530331334266	0.383295497001398
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1

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snRNP Assembly

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup85	ENSMUSG00000020739	0.0171027900598199	0.0513083701794598	0.208156293081417	0.312234439622125	1	1
Ndc1	ENSMUSG00000028614	0.511742979522636	0.642366752097095	0.141500034183268	0.424500102549803	0.642366752097095	0.642366752097095
Sec13	ENSMUSG00000030298	0.509798138101151	0.850721744111585	0.776919261684345	0.850721744111585	0.850721744111585	0.850721744111585
Nup37	ENSMUSG00000035351	0.454942951775341	0.781170242226513	0.781170242226513	0.781170242226513	0.578113371816017	0.781170242226513
Nup43	ENSMUSG00000040034	0.255530331334266	0.383295497001398	0.926550375688041	0.926550375688041	0.058823267388015	0.176469802164045
Snrpd2	ENSMUSG00000040824	0.0312459040565943	0.093737712169783	0.297095062262362	0.445642593393544	0.514300775319626	0.514300775319626
Snrpg	ENSMUSG00000057278	0.120545895661628	0.180818843492441	0.0236697127745139	0.0710091383235417	0.782117202022501	0.782117202022501
Gemin2	ENSMUSG00000060121	0.180293335960318	0.383295497001398	0.450444934184774	0.450444934184774	0.255530331334266	0.383295497001398
Snrpe	ENSMUSG00000090553	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	1	1

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Chromosome Maintenance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ten1	ENSMUSG00000020778	0.0325051220296005	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.576112968612194	0.576112968612194
Cenpp	ENSMUSG00000021391	0.578113371816017	0.78180291566155	0.78180291566155	0.78180291566155	0.178901132102685	0.536703396308054
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Mis18a	ENSMUSG00000022978	0.348008842235184	0.522013263352776	0.344663224299303	0.522013263352776	0.853694531487825	0.853694531487825
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Cenpl	ENSMUSG00000026708	0.254414773803597	0.508488713161374	0.342405296020881	0.508488713161374	0.508488713161374	0.508488713161374
Nop10	ENSMUSG00000027133	0.514300775319626	0.771451162979439	0.297848640636702	0.771451162979439	1	1
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Itgb3bp	ENSMUSG00000028549	0.399548817627028	0.399548817627028	0.294820734456232	0.399548817627028	0.211844580334808	0.399548817627028
Cenpa	ENSMUSG00000029177	0.0168921052924602	0.0253381579386902	0.00145633884669442	0.00436901654008325	0.852175490580835	0.852175490580835
Rbbp7	ENSMUSG00000031353	0.024062085667391	0.0721862570021731	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781
Smarca5	ENSMUSG00000031715	0.0953125666339397	0.142968849950909	0.0592616003460512	0.142968849950909	0.297848640636702	0.297848640636702
Rsf1	ENSMUSG00000035623	0.0964252305385472	0.144637845807821	0.0763619660358786	0.144637845807821	0.575536202757516	0.575536202757516
H2afz	ENSMUSG00000037894	0.395928178642446	0.780851835278818	0.780851835278818	0.780851835278818	0.780851835278817	0.780851835278818
Hist3h2ba	ENSMUSG00000056895	0.179945789077372	0.539837367232115	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
Hist1h4i	ENSMUSG00000060639	0.216214347033995	0.398108175780842	0.346527959006435	0.398108175780842	0.398108175780842	0.398108175780842
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544
Cenpw	ENSMUSG00000075266	0.255530331334266	0.383851786434906	0.255901190956604	0.383851786434906	0.514934023620345	0.514934023620345

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Purine catabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nudt9	ENSMUSG00000029310	0.641867098978198	0.852832278580641	0.852832278580641	0.852832278580641	0.447621891168214	0.852832278580641
Nudt1	ENSMUSG00000036639	0.399862618521905	0.399862618521905	0.00115309164684955	0.00345927494054866	0.0703913497478893	0.105587024621834
Dnph1	ENSMUSG00000040658	0.00481536616919075	0.0144460985075723	0.0164739112492867	0.02471086687393	0.710001140920767	0.710001140920767
Nudt18	ENSMUSG00000045211	5.62387620362728e-05	0.000168716286108818	0.00743512899358789	0.0111526934903818	0.121155015244363	0.121155015244363
Itpa	ENSMUSG00000074797	0.450794830295118	0.924872384323463	0.706616781330066	0.924872384323463	0.924872384323463	0.924872384323463

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Downstream TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Protein ubiquitination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Paf1	ENSMUSG00000003437	0.148772260628989	0.323235417174495	0.21549027811633	0.323235417174495	0.642366752097095	0.642366752097095
Ube2d1	ENSMUSG00000019927	0.216214347033995	0.324321520550992	0.0241933715424143	0.0725801146272428	0.853801250889739	0.853801250889739
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Ube2g1	ENSMUSG00000020794	0.395196379647461	0.513665062682276	0.513665062682276	0.513665062682276	0.399548817627028	0.513665062682276
Wac	ENSMUSG00000024283	0.119631084167592	0.324321520550992	0.216214347033995	0.324321520550992	0.514934023620344	0.514934023620344
Cdc73	ENSMUSG00000026361	0.708745765211584	0.708745765211584	0.0947558980989551	0.173937899428334	0.11595859961889	0.173937899428334
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513
Ube2q2	ENSMUSG00000032307	0.398108175780842	0.770497594023414	0.853372965654504	0.853372965654504	0.513665062682276	0.770497594023414
Rnf181	ENSMUSG00000055850	0.703556284613037	0.703556284613037	0.346527959006435	0.519791938509652	0.341647690705446	0.519791938509652
Wdr61	ENSMUSG00000061559	0.0269590270291413	0.080877081087424	0.563799176258241	0.845698764387362	0.924987846321933	0.924987846321933
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Hist2h2be	ENSMUSG00000068854	0.297095062262362	0.445642593393544	0.508488713161374	0.508488713161374	0.297095062262362	0.445642593393544

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RNA Polymerase III Transcription Initiation From Type 3 Promoter

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr3g	ENSMUSG00000035834	0.0753654386865988	0.226096316059796	0.299349060054895	0.449023590082343	0.708534948098331	0.708534948098331
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Metabolism of nucleotides

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Aprt	ENSMUSG00000006589	0.0443599545252852	0.0882349010820225	0.058823267388015	0.0882349010820225	0.782117202022501	0.782117202022501
Dguok	ENSMUSG00000014554	0.853480389728993	0.926550375688041	0.216214347033995	0.648643041101984	0.926550375688041	0.926550375688041
Nme2	ENSMUSG00000020857	0.0240240261603446	0.0720720784810337	0.63250023504486	0.84992097596507	0.84992097596507	0.84992097596507
Nudt13	ENSMUSG00000021809	0.024062085667391	0.072186257002173	0.254414773803597	0.381622160705395	0.78180291566155	0.78180291566155
Tk1	ENSMUSG00000025574	0.0236697127745139	0.0710091383235416	0.926604389137101	0.926604389137101	0.926496242814507	0.926604389137101
Txn1	ENSMUSG00000028367	0.0726276229843141	0.217882868952942	0.167569692867574	0.251354539301361	0.853480389728993	0.853480389728993
Nudt9	ENSMUSG00000029310	0.641867098978198	0.852832278580641	0.852832278580641	0.852832278580641	0.447621891168214	0.852832278580641
Nt5c3	ENSMUSG00000029780	0.852504981253341	0.853372965654504	0.214037080764326	0.642111242292977	0.853372965654504	0.853372965654504
Ctps2	ENSMUSG00000031360	0.180293335960318	0.540880007880955	0.926658283600152	0.926658283600152	0.78180291566155	0.926658283600152
Nudt1	ENSMUSG00000036639	0.399862618521905	0.399862618521905	0.00115309164684955	0.00345927494054866	0.0703913497478893	0.105587024621834
Dnph1	ENSMUSG00000040658	0.00481536616919075	0.0144460985075723	0.0164739112492867	0.02471086687393	0.710001140920767	0.710001140920767
Nudt18	ENSMUSG00000045211	5.62387620362728e-05	0.000168716286108818	0.00743512899358789	0.0111526934903818	0.121155015244363	0.121155015244363
Nme3	ENSMUSG00000073435	0.17750354896016	0.353909908268917	0.235939938845945	0.353909908268917	0.638310022345193	0.638310022345193
Itpa	ENSMUSG00000074797	0.450794830295118	0.924872384323463	0.706616781330066	0.924872384323463	0.924872384323463	0.924872384323463

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Interleukin-1 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb4	ENSMUSG00000005779	0.146800541856249	0.220200812784373	0.044737329683373	0.134211989050119	0.925669613555092	0.925669613555092
Psmd2	ENSMUSG00000006998	0.0117179415987427	0.0351538247962282	1	1	0.148772260628989	0.223158390943484
Psmd11	ENSMUSG00000017428	0.453570536021945	0.680355804032917	0.0761127945805735	0.228338383741721	0.781170242226513	0.781170242226513
Psmb6	ENSMUSG00000018286	0.700627001620904	0.923443907074248	0.923443907074248	0.923443907074248	0.146800541856249	0.440401625568747
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Map2k6	ENSMUSG00000020623	0.254414773803596	0.381622160705395	0.578113371816017	0.578113371816017	0.09586901335616	0.28760704006848
Psmb5	ENSMUSG00000022193	0.0761127945805735	0.11416919187086	0.0074351289935879	0.0223053869807637	0.705316781644051	0.705316781644051
Psmd9	ENSMUSG00000029440	0.0331400397096515	0.0497100595644772	0.0321889748775514	0.0497100595644772	0.178901132102685	0.178901132102685
Psmb10	ENSMUSG00000031897	0.000157492167861667	0.000472476503585	0.21549027811633	0.323235417174495	0.5155648232968	0.5155648232968
Psma3	ENSMUSG00000060073	0.298599969973533	0.520348625898199	0.346899083932133	0.520348625898199	0.643853282854191	0.643853282854191
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Psma5	ENSMUSG00000068749	0.00626486135808962	0.0187945840742689	0.329576740674783	0.494365111012175	0.565047747060087	0.565047747060087
Psmb3	ENSMUSG00000069744	0.12935516793705	0.388065503811151	0.559019965038563	0.635703516568382	0.635703516568382	0.635703516568382
Psme2	ENSMUSG00000079197	5.62387620362728e-05	0.000168716286108818	0.638824656785692	0.638824656785692	0.297095062262362	0.445642593393544

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Resolution of AP sites via the multiple-nucleotide patch replacement pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pole	ENSMUSG00000007080	0.0116356061791785	0.0349068185375355	0.0588232673880149	0.0882349010820223	0.643359829732651	0.643359829732651
Parg	ENSMUSG00000021911	0.640861491578951	0.853372965654504	0.577259514257969	0.853372965654504	0.853372965654504	0.853372965654504
Rfc4	ENSMUSG00000022881	0.0113089139751576	0.0339267419254727	0.179945789077372	0.269918683616058	0.853801250889739	0.853801250889739
Rfc2	ENSMUSG00000023104	0.0230207752632622	0.0690623257897866	0.514934023620345	0.514934023620345	0.0930846407079409	0.139626961061911
Pcna	ENSMUSG00000027342	0.643359829732651	0.781170242226513	0.45596561163947	0.781170242226513	0.781170242226513	0.781170242226513

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RNA Polymerase III Transcription Initiation From Type 2 Promoter

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr3g	ENSMUSG00000035834	0.0753654386865988	0.226096316059796	0.299349060054895	0.449023590082343	0.708534948098331	0.708534948098331
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017

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Signaling by FGFR2

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Polr2e	ENSMUSG00000004667	0.0763619660358786	0.229085898107636	0.926441990075769	0.926441990075769	0.255901190956603	0.383851786434905
Polr2i	ENSMUSG00000019738	0.148772260628989	0.446316781886967	0.578113371816017	0.711854160331342	0.711854160331342	0.711854160331342
Rps27a	ENSMUSG00000020460	0.214037080764326	0.642111242292977	0.710208797518812	0.710208797518812	0.514300775319626	0.710208797518812
Polr2h	ENSMUSG00000021018	0.177853449259986	0.533560347779959	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152
Polr2d	ENSMUSG00000024258	0.120545895661628	0.322146785907891	0.214764523938594	0.322146785907891	0.638310022345193	0.638310022345193
Polr2f	ENSMUSG00000033020	0.0703913497478892	0.17761387530773	0.118409250205154	0.17761387530773	0.578113371816017	0.578113371816017
Polr2l	ENSMUSG00000038489	0.0075577836449293	0.011336675467394	0.00145633884669441	0.00436901654008324	0.440372926628091	0.440372926628091
Polr2k	ENSMUSG00000045996	0.578113371816017	0.578113371816017	0.299349060054895	0.578113371816017	0.577829325134931	0.578113371816017
Hnrnpm	ENSMUSG00000059208	0.924987846321933	0.924987846321933	0.398108175780842	0.924987846321933	0.85117361048289	0.924987846321933
Gm11808	ENSMUSG00000068240	0.120850531362929	0.362551594088788	0.5155648232968	0.7733472349452	0.78180291566155	0.78180291566155
Polr2g	ENSMUSG00000071662	0.140165358447409	0.210248037671113	0.0964252305385473	0.210248037671113	0.925669613555092	0.925669613555092

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antiquewhite4

Ribosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Mrps10	ENSMUSG00000034729	0.92622377157404	0.92622377157404	0.398829756175299	0.92622377157404	0.711034989117171	0.92622377157404
Rpl21	ENSMUSG00000041453	0.570836132666921	0.856254199000382	1	1	0.144157978128026	0.432473934384078
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

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Coronavirus disease - COVID-19

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Mavs	ENSMUSG00000037523	0.21549027811633	0.21549027811633	0.11993617140438	0.179904257106569	0.115037265385284	0.179904257106569
Rpl21	ENSMUSG00000041453	0.570836132666921	0.856254199000382	1	1	0.144157978128026	0.432473934384078
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

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Proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Pomp	ENSMUSG00000029649	0.503822527122732	0.755733790684098	0.778911768167544	0.778911768167544	0.346899083932133	0.755733790684098
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Shfm1	ENSMUSG00000042541	0.340887582990546	0.569994097292072	0.637274134311157	0.637274134311157	0.379996064861382	0.569994097292072

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Translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Srp14	ENSMUSG00000009549	0.778911768167544	0.926333123228344	0.926333123228344	0.926333123228344	0.347639524025037	0.926333123228344
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

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SRP-dependent cotranslational protein targeting to membrane

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Srp14	ENSMUSG00000009549	0.778911768167544	0.926333123228344	0.926333123228344	0.926333123228344	0.347639524025037	0.926333123228344
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Major pathway of rRNA processing in the nucleolus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Pdcd11	ENSMUSG00000025047	0.178901132102685	0.268351698154027	1	1	0.0334587898203823	0.100376369461147
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Exosc9	ENSMUSG00000027714	0.578396848531894	0.578396848531894	0.456305241393103	0.578396848531894	0.578113371816017	0.578396848531894
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Nip7	ENSMUSG00000031917	0.643359829732651	0.643359829732651	0.248769231421035	0.373153847131552	0.245326864841172	0.373153847131552
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Las1l	ENSMUSG00000057421	0.146800541856249	0.440401625568746	0.926550375688041	0.926550375688041	0.398829756175299	0.598244634262948
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Nhp2l1	ENSMUSG00000063480	0.643359829732651	0.851732715229127	0.851732715229127	0.851732715229127	0.577829325134931	0.851732715229127
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

rRNA processing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Pdcd11	ENSMUSG00000025047	0.178901132102685	0.268351698154027	1	1	0.0334587898203823	0.100376369461147
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Exosc9	ENSMUSG00000027714	0.578396848531894	0.578396848531894	0.456305241393103	0.578396848531894	0.578113371816017	0.578396848531894
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Nip7	ENSMUSG00000031917	0.643359829732651	0.643359829732651	0.248769231421035	0.373153847131552	0.245326864841172	0.373153847131552
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Las1l	ENSMUSG00000057421	0.146800541856249	0.440401625568746	0.926550375688041	0.926550375688041	0.398829756175299	0.598244634262948
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Nhp2l1	ENSMUSG00000063480	0.643359829732651	0.851732715229127	0.851732715229127	0.851732715229127	0.577829325134931	0.851732715229127
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Formation of a pool of free 40S subunits

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

rRNA processing in the nucleus and cytosol

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Pdcd11	ENSMUSG00000025047	0.178901132102685	0.268351698154027	1	1	0.0334587898203823	0.100376369461147
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Exosc9	ENSMUSG00000027714	0.578396848531894	0.578396848531894	0.456305241393103	0.578396848531894	0.578113371816017	0.578396848531894
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Nip7	ENSMUSG00000031917	0.643359829732651	0.643359829732651	0.248769231421035	0.373153847131552	0.245326864841172	0.373153847131552
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Las1l	ENSMUSG00000057421	0.146800541856249	0.440401625568746	0.926550375688041	0.926550375688041	0.398829756175299	0.598244634262948
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Nhp2l1	ENSMUSG00000063480	0.643359829732651	0.851732715229127	0.851732715229127	0.851732715229127	0.577829325134931	0.851732715229127
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

L13a-mediated translational silencing of Ceruloplasmin expression

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

GTP hydrolysis and joining of the 60S ribosomal subunit

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Cap-dependent Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Eukaryotic Translation Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

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Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Metabolism of RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nxf1	ENSMUSG00000010097	0.45596561163947	0.711650020253571	0.5155648232968	0.711650020253571	0.711650020253571	0.711650020253571
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Pdcd11	ENSMUSG00000025047	0.178901132102685	0.268351698154027	1	1	0.0334587898203823	0.100376369461147
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Exosc9	ENSMUSG00000027714	0.578396848531894	0.578396848531894	0.456305241393103	0.578396848531894	0.578113371816017	0.578396848531894
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Nip7	ENSMUSG00000031917	0.643359829732651	0.643359829732651	0.248769231421035	0.373153847131552	0.245326864841172	0.373153847131552
Dcps	ENSMUSG00000032040	0.148772260628989	0.446316781886968	0.514934023620345	0.514934023620345	0.348008842235184	0.514934023620345
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
0610009D07Rik	ENSMUSG00000037361	0.297095062262362	0.445642593393544	0.573498913947369	0.573498913947369	0.294820734456232	0.445642593393544
Bud31	ENSMUSG00000038722	0.575536202757516	0.578113371816017	0.578113371816017	0.578113371816017	0.347639524025037	0.578113371816017
Naa38	ENSMUSG00000044155	0.63250023504486	0.847317797849051	0.847317797849051	0.847317797849051	0.345037391052887	0.847317797849051
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Gemin6	ENSMUSG00000055760	0.044926265292481	0.134778795877443	0.926658283600152	0.926658283600152	0.255530331334266	0.383295497001398
Las1l	ENSMUSG00000057421	0.146800541856249	0.440401625568746	0.926550375688041	0.926550375688041	0.398829756175299	0.598244634262948
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Nhp2l1	ENSMUSG00000063480	0.643359829732651	0.851732715229127	0.851732715229127	0.851732715229127	0.577829325134931	0.851732715229127
Prpf38a	ENSMUSG00000063800	0.514934023620344	0.772401035430516	0.298599969973533	0.772401035430516	0.852065168704833	0.852065168704833
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Nonsense-Mediated Decay (NMD)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

Download data as csv

Metabolism of proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nr1h3	ENSMUSG00000002108	0.711854160331342	0.853801250889739	0.180293335960318	0.540880007880955	0.853801250889739	0.853801250889739
Srp14	ENSMUSG00000009549	0.778911768167544	0.926333123228344	0.926333123228344	0.926333123228344	0.347639524025037	0.926333123228344
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rpl19	ENSMUSG00000017404	0.78180291566155	0.78180291566155	0.254414773803597	0.763244321410791	0.780851835278818	0.78180291566155
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Rab1	ENSMUSG00000020149	0.852504981253341	0.926003599371281	0.120850531362929	0.362551594088788	0.926003599371281	0.926003599371281
Gfpt2	ENSMUSG00000020363	0.214401013708444	0.643203041125333	1	1	1	1
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Sec11c	ENSMUSG00000024516	0.454942951775341	0.852504981253341	0.852504981253341	0.852504981253341	0.704220158648919	0.852504981253341
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Cops5	ENSMUSG00000025917	0.578113371816017	0.852504981253341	0.17433930265919	0.523017907977569	0.852504981253341	0.852504981253341
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Copa	ENSMUSG00000026553	0.120850531362929	0.120850531362929	0.118714930081337	0.120850531362929	0.11810342389482	0.120850531362929
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Cst3	ENSMUSG00000027447	0.148772260628989	0.446316781886968	0.78180291566155	0.78180291566155	0.395928178642446	0.593892267963669
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Fuca1	ENSMUSG00000028673	1	1	0.514934023620345	1	0.926003599371282	1
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Rpl6	ENSMUSG00000029614	0.45596561163947	0.511742979522636	0.209636747299872	0.511742979522636	0.511742979522636	0.511742979522636
Rab19	ENSMUSG00000029923	0.0241933715424143	0.0725801146272428	0.399548817627028	0.599323226440542	0.782117202022501	0.782117202022501
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
F10	ENSMUSG00000031444	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344	0.926333123228344	0.926333123228344
Dctn6	ENSMUSG00000031516	0.926333123228344	0.926333123228344	0.0592616003460512	0.177784801038154	0.578113371816017	0.867170057724026
Thsd4	ENSMUSG00000032289	0.853372965654504	0.853372965654504	0.708745765211584	0.853372965654504	0.643853282854191	0.853372965654504
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Rpl18a	ENSMUSG00000045128	0.300095920620218	0.852065168704833	0.852065168704833	0.852065168704833	0.640355507848752	0.852065168704833
Rpl29	ENSMUSG00000048758	0.852940894477647	0.852940894477647	0.346899083932133	0.852940894477647	0.706831781264721	0.852940894477647
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Commd3	ENSMUSG00000051154	0.853801250889739	0.853801250889739	0.642366752097095	0.853801250889739	0.853801250889739	0.853801250889739
Commd1	ENSMUSG00000051355	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968	0.513665062682276	0.5155648232968
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Fbxo6	ENSMUSG00000055401	0.513665062682276	0.772401035430517	0.514934023620345	0.772401035430517	0.78180291566155	0.78180291566155
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Apol8	ENSMUSG00000056656	0.514300775319626	0.514300775319626	0.294820734456232	0.445642593393544	0.297095062262363	0.445642593393544
Rpl30	ENSMUSG00000058600	0.852504981253341	0.853480389728993	0.575536202757516	0.853480389728993	0.853480389728993	0.853480389728993
Rpl11	ENSMUSG00000059291	0.780851835278818	0.780851835278818	0.253294730253594	0.597162263671263	0.398108175780842	0.597162263671263
Rpl35a	ENSMUSG00000060636	0.926333123228344	0.926333123228344	0.576112968612194	0.926333123228344	0.640861491578951	0.926333123228344
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282
Rpl7a	ENSMUSG00000062647	0.0936419271039908	0.280925781311972	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765
Rpl23	ENSMUSG00000071415	0.577829325134931	0.577829325134931	0.576973746230334	0.577829325134931	0.178901132102685	0.536703396308054
Rpl31	ENSMUSG00000073702	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.0964252305385472	0.289275691615642
Rpl13a	ENSMUSG00000074129	0.7802108304765	0.7802108304765	0.511742979522636	0.767614469283954	0.346527959006435	0.767614469283954

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S Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813

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Cell Cycle Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Synthesis of DNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Transcriptional regulation by RUNX2

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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DNA Replication

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Formation of the ternary complex, and subsequently, the 43S complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282

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Regulation of RUNX2 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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G1/S Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Cyclin E associated events during G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Switching of origins to a post-replicative state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Ribosomal scanning and start codon recognition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282

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Translation initiation complex formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282

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Degradation of GLI1 by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Cyclin A:Cdk2-associated events at S phase entry

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif3e	ENSMUSG00000022336	0.395196379647461	0.592794569471191	0.255901190956604	0.592794569471191	0.853694531487825	0.853694531487825
Rps24	ENSMUSG00000025290	0.853801250889739	0.853801250889739	0.577829325134931	0.853801250889739	0.399548817627028	0.853801250889739
Rps3a1	ENSMUSG00000028081	0.711854160331342	0.711854160331342	0.643359829732651	0.711854160331342	0.299349060054895	0.711854160331342
Eif3i	ENSMUSG00000028798	0.0723789610264069	0.217136883079221	0.639337105615665	0.85117361048289	0.85117361048289	0.85117361048289
Rpsa	ENSMUSG00000032518	1	1	0.249907451332337	0.749722353997012	0.853372965654504	1
Rps23	ENSMUSG00000049517	0.643853282854191	0.780851835278817	0.780851835278817	0.780851835278817	0.250285839267991	0.750857517803972
Rps10	ENSMUSG00000052146	0.642864324224729	0.642864324224729	0.578113371816017	0.642864324224729	0.400265374208515	0.642864324224729
Rps7	ENSMUSG00000061477	0.711240436189781	0.711240436189781	0.642864324224729	0.711240436189781	0.398108175780842	0.711240436189781
Rps17	ENSMUSG00000061787	0.853372965654504	0.926003599371282	0.926003599371282	0.926003599371282	0.449391287230099	0.926003599371282

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GLI3 is processed to GLI3R by the proteasome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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G2/M Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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Neddylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Cops5	ENSMUSG00000025917	0.578113371816017	0.852504981253341	0.17433930265919	0.523017907977569	0.852504981253341	0.852504981253341
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Commd3	ENSMUSG00000051154	0.853801250889739	0.853801250889739	0.642366752097095	0.853801250889739	0.853801250889739	0.853801250889739
Commd1	ENSMUSG00000051355	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968	0.513665062682276	0.5155648232968
Fbxo6	ENSMUSG00000055401	0.513665062682276	0.772401035430517	0.514934023620345	0.772401035430517	0.78180291566155	0.78180291566155
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306

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SCF(Skp2)-mediated degradation of p27/p21

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Cell Cycle, Mitotic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Rab1	ENSMUSG00000020149	0.852504981253341	0.926003599371281	0.120850531362929	0.362551594088788	0.926003599371281	0.926003599371281
Vrk1	ENSMUSG00000021115	0.0150443553124285	0.0451330659372854	0.92589277149125	0.92589277149125	0.710001140920767	0.92589277149125
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Rab1	ENSMUSG00000020149	0.852504981253341	0.926003599371281	0.120850531362929	0.362551594088788	0.926003599371281	0.926003599371281
Vrk1	ENSMUSG00000021115	0.0150443553124285	0.0451330659372854	0.92589277149125	0.92589277149125	0.710001140920767	0.92589277149125
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Mitotic G1 phase and G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Cks1b	ENSMUSG00000028044	0.0236697127745139	0.0710091383235416	0.711445446052875	0.92616891281798	0.92616891281798	0.92616891281798
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306

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APC/C:Cdc20 mediated degradation of Securin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Cellular response to hypoxia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306

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Orc1 removal from chromatin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Mitotic Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Vrk1	ENSMUSG00000021115	0.0150443553124285	0.0451330659372854	0.92589277149125	0.92589277149125	0.710001140920767	0.92589277149125
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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CDK-mediated phosphorylation and removal of Cdc6

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Mitotic Metaphase and Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Vrk1	ENSMUSG00000021115	0.0150443553124285	0.0451330659372854	0.92589277149125	0.92589277149125	0.710001140920767	0.92589277149125
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Degradation of DVL

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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NIK–>noncanonical NF-kB signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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ABC-family proteins mediated transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Sel1l	ENSMUSG00000020964	0.708534948098331	1	1	1	0.250285839267991	0.750857517803972
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Erlin2	ENSMUSG00000031483	1	1	0.853480389728993	1	0.513665062682276	1
Abca6	ENSMUSG00000044749	0.926003599371282	0.926003599371282	0.571432149807741	0.857148224711611	0.345410946355105	0.857148224711611

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Degradation of beta-catenin by the destruction complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Hedgehog ‘on’ state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Gpr161	ENSMUSG00000040836	0.346899083932133	0.5203486258982	0.782117202022501	0.782117202022501	0.346899083932133	0.5203486258982

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DNA Replication Pre-Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Prim1	ENSMUSG00000025395	0.711240436189781	0.711240436189781	0.177153312234059	0.531459936702178	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Activation of NF-kappaB in B cells

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Separation of Sister Chromatids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Hedgehog ‘off’ state

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Gpr161	ENSMUSG00000040836	0.346899083932133	0.5203486258982	0.782117202022501	0.782117202022501	0.346899083932133	0.5203486258982

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Hedgehog ligand biogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Sel1l	ENSMUSG00000020964	0.708534948098331	1	1	1	0.250285839267991	0.750857517803972
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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APC/C-mediated degradation of cell cycle proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Regulation of mitotic cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Regulation of RAS by GAPs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Cross-presentation of soluble exogenous antigens (endosomes)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Signaling by Hedgehog

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Sel1l	ENSMUSG00000020964	0.708534948098331	1	1	1	0.250285839267991	0.750857517803972
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Gpr161	ENSMUSG00000040836	0.346899083932133	0.5203486258982	0.782117202022501	0.782117202022501	0.346899083932133	0.5203486258982

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Regulation of ornithine decarboxylase (ODC)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Ubiquitin-dependent degradation of Cyclin D

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Autodegradation of the E3 ubiquitin ligase COP1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Interleukin-1 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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p53-Independent DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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p53-Independent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Regulation of RUNX3 expression and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Degradation of AXIN

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Downstream signaling events of B Cell Receptor (BCR)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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G2/M Transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012

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Stabilization of p53

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Mitotic G2-G2/M phases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012

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Transcriptional regulation by RUNX3

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Metabolism of polyamines

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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CDT1 association with the CDC6:ORC:origin complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Interleukin-1 family signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Exosc9	ENSMUSG00000027714	0.578396848531894	0.578396848531894	0.456305241393103	0.578396848531894	0.578113371816017	0.578396848531894
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Asymmetric localization of PCP proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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p53-Dependent G1/S DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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p53-Dependent G1 DNA Damage Response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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RUNX1 regulates transcription of genes involved in differentiation of HSCs

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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G1/S DNA Damage Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Assembly of the pre-replicative complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Downstream TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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CLEC7A (Dectin-1) signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Regulation of PTEN stability and activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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TNFR2 non-canonical NF-kB pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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MAPK6/MAPK4 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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The role of GTSE1 in G2/M progression after G2 checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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M Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Rab1	ENSMUSG00000020149	0.852504981253341	0.926003599371281	0.120850531362929	0.362551594088788	0.926003599371281	0.926003599371281
Vrk1	ENSMUSG00000021115	0.0150443553124285	0.0451330659372854	0.92589277149125	0.92589277149125	0.710001140920767	0.92589277149125
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Antigen processing: Ubiquitination & Proteasome degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Fbxo6	ENSMUSG00000055401	0.513665062682276	0.772401035430517	0.514934023620345	0.772401035430517	0.78180291566155	0.78180291566155
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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C-type lectin receptors (CLRs)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Cellular responses to stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Atp6v1e1	ENSMUSG00000019210	0.636229315311352	0.850721744111585	0.850721744111585	0.850721744111585	0.146141353215796	0.438424059647387
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Atp6v1c1	ENSMUSG00000022295	0.511742979522636	0.578113371816017	0.578113371816017	0.578113371816017	0.346527959006435	0.578113371816017
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Dctn6	ENSMUSG00000031516	0.926333123228344	0.926333123228344	0.0592616003460512	0.177784801038154	0.578113371816017	0.867170057724026
Atp6v1g1	ENSMUSG00000039105	0.853694531487825	0.853694531487825	0.454600801949285	0.681901202923927	0.253294730253594	0.681901202923927
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Cellular responses to external stimuli

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Atp6v1e1	ENSMUSG00000019210	0.636229315311352	0.850721744111585	0.850721744111585	0.850721744111585	0.146141353215796	0.438424059647387
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Atp6v1c1	ENSMUSG00000022295	0.511742979522636	0.578113371816017	0.578113371816017	0.578113371816017	0.346527959006435	0.578113371816017
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Dctn6	ENSMUSG00000031516	0.926333123228344	0.926333123228344	0.0592616003460512	0.177784801038154	0.578113371816017	0.867170057724026
Atp6v1g1	ENSMUSG00000039105	0.853694531487825	0.853694531487825	0.454600801949285	0.681901202923927	0.253294730253594	0.681901202923927
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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PCP/CE pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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G2/M DNA damage checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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Antigen processing-Cross presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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UCH proteinases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Transport of small molecules

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc7a7	ENSMUSG00000000958	0.398108175780842	0.683948417459205	1	1	0.45596561163947	0.683948417459205
Nr1h3	ENSMUSG00000002108	0.711854160331342	0.853801250889739	0.180293335960318	0.540880007880955	0.853801250889739	0.853801250889739
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Atp6v1e1	ENSMUSG00000019210	0.636229315311352	0.850721744111585	0.850721744111585	0.850721744111585	0.146141353215796	0.438424059647387
Sel1l	ENSMUSG00000020964	0.708534948098331	1	1	1	0.250285839267991	0.750857517803972
Npc2	ENSMUSG00000021242	0.0562022152993846	0.168606645898154	0.852065168704833	0.852065168704833	0.249907451332337	0.374861176998505
Atp6v1c1	ENSMUSG00000022295	0.511742979522636	0.578113371816017	0.578113371816017	0.578113371816017	0.346527959006435	0.578113371816017
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Stoml2	ENSMUSG00000028455	0.346527959006435	0.853907737111068	0.853907737111068	0.853907737111068	0.711034989117171	0.853907737111068
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Atp2b3	ENSMUSG00000031376	0.514934023620345	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Erlin2	ENSMUSG00000031483	1	1	0.853480389728993	1	0.513665062682276	1
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Slc18a1	ENSMUSG00000036330	1	1	0.21549027811633	0.64647083434899	0.853694531487825	1
Atp6v1g1	ENSMUSG00000039105	0.853694531487825	0.853694531487825	0.454600801949285	0.681901202923927	0.253294730253594	0.681901202923927
Apoc1	ENSMUSG00000040564	0.215852522998048	0.323778784497071	0.711034989117171	0.711034989117171	0.179597906187076	0.323778784497071
Trpv3	ENSMUSG00000043029	0.252920381501207	0.435315022773717	0.290210015182478	0.435315022773717	0.577829325134931	0.577829325134931
Abca6	ENSMUSG00000044749	0.926003599371282	0.926003599371282	0.571432149807741	0.857148224711611	0.345410946355105	0.857148224711611

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Polo-like kinase mediated events

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Wee1	ENSMUSG00000031016	0.643359829732651	0.643359829732651	0.514934023620345	0.643359829732651	0.0953125666339397	0.285937699901819
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012

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Class I MHC mediated antigen processing & presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Fbxo6	ENSMUSG00000055401	0.513665062682276	0.772401035430517	0.514934023620345	0.772401035430517	0.78180291566155	0.78180291566155
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686

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Mitochondrial translation elongation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977

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PTEN Regulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Transcriptional regulation by RUNX1

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Dpy30	ENSMUSG00000024067	0.926658283600152	0.926658283600152	0.400265374208515	0.682414427663012	0.454942951775341	0.682414427663012
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Sin3b	ENSMUSG00000031622	0.509798138101151	0.514934023620345	0.0575107614292585	0.172532284287776	0.514934023620345	0.514934023620345
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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Mitochondrial translation termination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977

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Mitochondrial translation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mrpl24	ENSMUSG00000019710	0.447621891168213	0.671432836752319	0.252545530864481	0.671432836752319	0.924872384323463	0.924872384323463
Mrpl13	ENSMUSG00000022370	0.400265374208515	0.78180291566155	0.78180291566155	0.78180291566155	0.643359829732651	0.78180291566155
Mrpl21	ENSMUSG00000024829	0.578396848531894	0.643359829732651	0.643359829732651	0.643359829732651	0.578113371816017	0.643359829732651
Mrpl20	ENSMUSG00000029066	1	1	0.852832278580641	1	0.454600801949285	1
Mrps21	ENSMUSG00000054312	0.711034989117171	0.926658283600152	0.926658283600152	0.926658283600152	0.456305241393103	0.926658283600152
Mrps9	ENSMUSG00000060679	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.214037080764326	0.642111242292977

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TCF dependent signaling in response to WNT

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Processing of DNA double-strand break ends

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Tipin	ENSMUSG00000032397	0.21549027811633	0.64647083434899	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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DNA Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Trim25	ENSMUSG00000000275	0.853801250889739	0.926658283600152	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152
Eya4	ENSMUSG00000010461	0.851843781957086	0.851843781957086	0.503145129266073	0.851843781957086	0.778911768167544	0.851843781957086
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Cops5	ENSMUSG00000025917	0.578113371816017	0.852504981253341	0.17433930265919	0.523017907977569	0.852504981253341	0.852504981253341
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Tipin	ENSMUSG00000032397	0.21549027811633	0.64647083434899	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155
Apex1	ENSMUSG00000035960	0.0964252305385472	0.289275691615642	0.249907451332337	0.374861176998506	0.926550375688041	0.926550375688041
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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Beta-catenin independent WNT signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Generic Transcription Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nr1h3	ENSMUSG00000002108	0.711854160331342	0.853801250889739	0.180293335960318	0.540880007880955	0.853801250889739	0.853801250889739
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Dpy30	ENSMUSG00000024067	0.926658283600152	0.926658283600152	0.400265374208515	0.682414427663012	0.454942951775341	0.682414427663012
Taf11	ENSMUSG00000024218	0.578396848531894	0.782117202022501	0.577829325134931	0.782117202022501	0.782117202022501	0.782117202022501
Cox7a2l	ENSMUSG00000024248	0.711034989117171	0.711034989117171	0.708323672944427	0.711034989117171	0.455625354715449	0.711034989117171
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Zfp108	ENSMUSG00000030486	0.120850531362929	0.362551594088788	0.925837170483845	0.925837170483845	0.778418649115106	0.925837170483845
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Sin3b	ENSMUSG00000031622	0.509798138101151	0.514934023620345	0.0575107614292585	0.172532284287776	0.514934023620345	0.514934023620345
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Cdc25c	ENSMUSG00000044201	0.00468160475316414	0.0140448142594924	0.338592117141989	0.338592117141989	0.170434860179341	0.255652290269012
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226
Zfp954	ENSMUSG00000062116	0.348008842235185	0.711650020253571	0.711650020253571	0.711650020253571	0.643853282854191	0.711650020253571
Zfp35	ENSMUSG00000063281	0.643359829732651	1	0.781170242226513	1	1	1

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Post-translational protein modification

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nr1h3	ENSMUSG00000002108	0.711854160331342	0.853801250889739	0.180293335960318	0.540880007880955	0.853801250889739	0.853801250889739
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Rab1	ENSMUSG00000020149	0.852504981253341	0.926003599371281	0.120850531362929	0.362551594088788	0.926003599371281	0.926003599371281
Gfpt2	ENSMUSG00000020363	0.214401013708444	0.643203041125333	1	1	1	1
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Dcaf13	ENSMUSG00000022300	0.78180291566155	0.78180291566155	0.347639524025037	0.78180291566155	0.711240436189781	0.78180291566155
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Cops5	ENSMUSG00000025917	0.578113371816017	0.852504981253341	0.17433930265919	0.523017907977569	0.852504981253341	0.852504981253341
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Copa	ENSMUSG00000026553	0.120850531362929	0.120850531362929	0.118714930081337	0.120850531362929	0.11810342389482	0.120850531362929
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Cst3	ENSMUSG00000027447	0.148772260628989	0.446316781886968	0.78180291566155	0.78180291566155	0.395928178642446	0.593892267963669
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Fuca1	ENSMUSG00000028673	1	1	0.514934023620345	1	0.926003599371282	1
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Rab19	ENSMUSG00000029923	0.0241933715424143	0.0725801146272428	0.399548817627028	0.599323226440542	0.782117202022501	0.782117202022501
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
F10	ENSMUSG00000031444	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344	0.926333123228344	0.926333123228344
Dctn6	ENSMUSG00000031516	0.926333123228344	0.926333123228344	0.0592616003460512	0.177784801038154	0.578113371816017	0.867170057724026
Thsd4	ENSMUSG00000032289	0.853372965654504	0.853372965654504	0.708745765211584	0.853372965654504	0.643853282854191	0.853372965654504
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883
Fbxl7	ENSMUSG00000043556	1	1	0.925948247631505	1	0.296717426617604	0.890152279852813
Commd3	ENSMUSG00000051154	0.853801250889739	0.853801250889739	0.642366752097095	0.853801250889739	0.853801250889739	0.853801250889739
Commd1	ENSMUSG00000051355	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968	0.513665062682276	0.5155648232968
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Fbxo6	ENSMUSG00000055401	0.513665062682276	0.772401035430517	0.514934023620345	0.772401035430517	0.78180291566155	0.78180291566155
Tceb2	ENSMUSG00000055839	0.570836132666921	0.570836132666921	0.444394285043028	0.570836132666921	0.171859370212435	0.515578110637306
Apol8	ENSMUSG00000056656	0.514300775319626	0.514300775319626	0.294820734456232	0.445642593393544	0.297095062262363	0.445642593393544
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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Prolactin receptor signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rbx1	ENSMUSG00000022400	0.511742979522636	0.511742979522636	0.174692232033629	0.262038348050444	0.147458757705095	0.262038348050444
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Mitotic Spindle Checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Spc25	ENSMUSG00000005233	0.454600801949285	0.681901202923927	0.711240436189781	0.711240436189781	0.347639524025037	0.681901202923927
Zwint	ENSMUSG00000019923	0.146141353215796	0.255652290269012	0.170434860179341	0.255652290269012	0.849805525376199	0.849805525376199
Ube2e1	ENSMUSG00000021774	0.511097249598474	0.778911768167544	0.778911768167544	0.778911768167544	0.708534948098331	0.778911768167544
Ndc80	ENSMUSG00000024056	0.852504981253341	1	0.400265374208515	1	1	1
Cdc26	ENSMUSG00000066149	1	1	0.643359829732651	0.965039744598977	0.299349060054895	0.898047180164686
Apitd1	ENSMUSG00000073705	0.120545895661628	0.361637686984883	0.853801250889739	0.92622377157404	0.92622377157404	0.92622377157404

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FCERI mediated NF-kB activation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282
Skp1a	ENSMUSG00000036309	0.92622377157404	0.92622377157404	0.346527959006435	0.519791938509652	0.120545895661628	0.361637686984883

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Ub-specific processing proteases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Smad4	ENSMUSG00000024515	0.455625354715448	0.683438032073173	0.146141353215796	0.438424059647387	0.711240436189781	0.711240436189781
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Psma7	ENSMUSG00000027566	0.777255087907932	0.848280005680805	0.389247465657472	0.848280005680805	0.848280005680805	0.848280005680805
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Psma1	ENSMUSG00000030751	0.451840588205062	0.677760882307593	0.400265374208515	0.677760882307593	1	1
Psmd10	ENSMUSG00000031429	0.453225835454266	0.926003599371282	0.926003599371282	0.926003599371282	0.924987846321933	0.926003599371282

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Insulin receptor recycling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp6v1e1	ENSMUSG00000019210	0.636229315311352	0.850721744111585	0.850721744111585	0.850721744111585	0.146141353215796	0.438424059647387
Atp6v1c1	ENSMUSG00000022295	0.511742979522636	0.578113371816017	0.578113371816017	0.578113371816017	0.346527959006435	0.578113371816017
Atp6v1g1	ENSMUSG00000039105	0.853694531487825	0.853694531487825	0.454600801949285	0.681901202923927	0.253294730253594	0.681901202923927

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Neutrophil degranulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cstb	ENSMUSG00000005054	0.573498913947369	0.710001140920767	0.509798138101151	0.710001140920767	0.710001140920767	0.710001140920767
Srp14	ENSMUSG00000009549	0.778911768167544	0.926333123228344	0.926333123228344	0.926333123228344	0.347639524025037	0.926333123228344
Psmb1	ENSMUSG00000014769	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.148115998140416	0.444347994421247
Psma2	ENSMUSG00000015671	0.072627622984314	0.217882868952942	1	1	0.397384062266614	0.596076093399921
Npc2	ENSMUSG00000021242	0.0562022152993846	0.168606645898154	0.852065168704833	0.852065168704833	0.249907451332337	0.374861176998505
Igf2r	ENSMUSG00000023830	0.781170242226513	0.781170242226513	0.710208797518812	0.781170242226513	0.45596561163947	0.781170242226513
Ostf1	ENSMUSG00000024725	0.853480389728993	0.853480389728993	0.179945789077372	0.539837367232116	0.57113445032749	0.853480389728993
Prdx4	ENSMUSG00000025289	0.575824878403157	0.9255572759333	0.852175490580835	0.9255572759333	0.9255572759333	0.9255572759333
Psmb7	ENSMUSG00000026750	0.173632433887832	0.520897301663497	1	1	0.577259514257969	0.865889271386954
Cst3	ENSMUSG00000027447	0.148772260628989	0.446316781886968	0.78180291566155	0.78180291566155	0.395928178642446	0.593892267963669
Fuca1	ENSMUSG00000028673	1	1	0.514934023620345	1	0.926003599371282	1
Psmc2	ENSMUSG00000028932	0.0148445652050919	0.0445336956152758	0.513665062682276	0.635703516568382	0.635703516568382	0.635703516568382
Gla	ENSMUSG00000031266	0.300095920620218	0.637274134311157	0.572616808177226	0.637274134311157	0.637274134311157	0.637274134311157
Anxa2	ENSMUSG00000032231	0.256271555563966	0.384407333345949	0.119936171404379	0.359808514213138	0.450444934184774	0.450444934184774
Commd3	ENSMUSG00000051154	0.853801250889739	0.853801250889739	0.642366752097095	0.853801250889739	0.853801250889739	0.853801250889739
Serpinb6a	ENSMUSG00000060147	0.299349060054895	0.299349060054895	0.148115998140416	0.299349060054895	0.202920309846333	0.299349060054895

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DNA Double-Strand Break Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eya4	ENSMUSG00000010461	0.851843781957086	0.851843781957086	0.503145129266073	0.851843781957086	0.778911768167544	0.851843781957086
Rpa3	ENSMUSG00000012483	0.853694531487825	0.853694531487825	0.576973746230334	0.853694531487825	0.455625354715449	0.853694531487825
Rad1	ENSMUSG00000022248	0.577259514257969	0.78180291566155	0.300095920620218	0.78180291566155	0.78180291566155	0.78180291566155
Sumo1	ENSMUSG00000026021	0.180293335960318	0.511331374485819	0.340887582990546	0.511331374485819	0.779888212132595	0.779888212132595
Tipin	ENSMUSG00000032397	0.21549027811633	0.64647083434899	0.576973746230334	0.78180291566155	0.78180291566155	0.78180291566155
Bre	ENSMUSG00000052139	0.337435786255283	0.392985378348026	0.392985378348026	0.392985378348026	0.300095920620218	0.392985378348026
Hist1h4d	ENSMUSG00000061482	0.505169133438821	0.572616808177226	0.572616808177226	0.572616808177226	0.5155648232968	0.572616808177226

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blue1

MAPK signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ngfr	ENSMUSG00000000120	0.297848640636702	0.446772960955053	0.297848640636702	0.446772960955053	0.853801250889739	0.853801250889739
Gna12	ENSMUSG00000000149	0.0964252305385471	0.144637845807821	0.0315593554855452	0.0946780664566357	0.635703516568382	0.635703516568382
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Daxx	ENSMUSG00000002307	0.0168921052924601	0.0506763158773803	0.058823267388015	0.0882349010820225	0.455625354715449	0.455625354715449
Rps6ka1	ENSMUSG00000003644	0.25141795904251	0.521459286037555	0.347639524025037	0.521459286037555	1	1
Map3k11	ENSMUSG00000004054	0.11810342389482	0.354310271684459	0.642366752097095	0.853049270252403	0.853049270252403	0.853049270252403
Hspb1	ENSMUSG00000004951	0.508488713161374	0.508488713161374	0.0331400397096515	0.0994201191289544	0.120850531362929	0.181275797044394
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Tek	ENSMUSG00000006386	0.11993617140438	0.179904257106569	0.0964252305385472	0.179904257106569	0.853801250889739	0.853801250889739
Mapkapk2	ENSMUSG00000016528	0.0116356061791785	0.0253381579386902	0.0168921052924602	0.0253381579386902	0.707899741868332	0.707899741868332
Nlk	ENSMUSG00000017376	0.853694531487825	0.853694531487825	0.0451153644990944	0.135346093497283	0.400265374208515	0.600398061312773
Map2k3	ENSMUSG00000018932	0.0325051220296005	0.0975153660888015	0.300095920620218	0.344663224299303	0.344663224299303	0.344663224299303
Mknk2	ENSMUSG00000020190	0.0763619660358786	0.181275797044394	0.120850531362929	0.181275797044394	0.246478961478169	0.246478961478169
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Cacnb1	ENSMUSG00000020882	0.119631084167592	0.179446626251388	0.0964252305385473	0.179446626251388	0.926550375688041	0.926550375688041
Mapk8ip2	ENSMUSG00000022619	0.643359829732651	0.643359829732651	0.0969812105731562	0.290943631719469	0.578113371816017	0.643359829732651
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Ddit3	ENSMUSG00000025408	0.0763619660358786	0.229085898107636	0.853694531487825	0.853694531487825	0.575824878403157	0.853694531487825
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Il1r1	ENSMUSG00000026072	0.851061028660105	0.851061028660105	0.146800541856249	0.424701993236134	0.283134662157423	0.424701993236134
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Ntrk1	ENSMUSG00000028072	0.416823357713009	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Stmn1	ENSMUSG00000028832	0.0527343611033823	0.0791015416550734	0.030001399289448	0.0791015416550734	0.11810342389482	0.11810342389482
Flt1	ENSMUSG00000029648	0.45596561163947	0.513665062682276	0.148115998140416	0.444347994421247	0.513665062682276	0.513665062682276
Pak1	ENSMUSG00000030774	0.0117179415987427	0.0351538247962282	0.399548817627028	0.399548817627028	0.142165951159432	0.213248926739148
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Gadd45a	ENSMUSG00000036390	0.926550375688041	0.926550375688041	0.119936171404379	0.319961917328694	0.213307944885796	0.319961917328694
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Pla2g4f	ENSMUSG00000046971	0.0409950409136847	0.122985122741054	0.512386180848416	0.512386180848416	0.296339225025931	0.444508837538896
Ntf3	ENSMUSG00000049107	1	1	0.00289311433957183	0.00867934301871549	0.447621891168214	0.671432836752321
Map2k5	ENSMUSG00000058444	0.148115998140415	0.264150874616835	0.17610058307789	0.264150874616835	1	1
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Hspa2	ENSMUSG00000059970	0.576973746230334	0.576973746230334	0.0579478375430677	0.173843512629203	0.255901190956604	0.383851786434906
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Ecsit	ENSMUSG00000066839	0.642864324224729	0.643359829732651	0.177153312234059	0.531459936702177	0.643359829732651	0.643359829732651
Jund	ENSMUSG00000071076	0.926550375688041	0.926550375688041	0.179945789077371	0.447899954960299	0.298599969973533	0.447899954960299
PLA2G4B	ENSMUSG00000098488	0.505838378028518	0.758757567042777	0.9255572759333	0.9255572759333	0.453225835454266	0.758757567042777

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Bladder cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Dapk3	ENSMUSG00000034974	0.781170242226513	0.926658283600152	0.09586901335616	0.28760704006848	0.926658283600152	0.926658283600152
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Wnt signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Serpinf1	ENSMUSG00000000753	0.180293335960318	0.270440003940477	0.0592616003460512	0.177784801038154	0.853801250889739	0.853801250889739
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Nlk	ENSMUSG00000017376	0.853694531487825	0.853694531487825	0.0451153644990944	0.135346093497283	0.400265374208515	0.600398061312773
Sfrp5	ENSMUSG00000018822	0.78148726569172	0.78148726569172	0.024062085667391	0.072186257002173	0.348008842235184	0.522013263352777
Rspo3	ENSMUSG00000019880	0.643359829732651	0.643359829732651	0.113498953177704	0.340496859533111	0.342026805366747	0.51304020805012
Fbxw11	ENSMUSG00000020271	0.346899083932133	0.575536202757516	0.575536202757516	0.575536202757516	0.514300775319626	0.575536202757516
Ror2	ENSMUSG00000021464	0.712057867818062	0.712057867818062	0.348377561241889	0.522566341862834	0.211844580334808	0.522566341862834
Nkd2	ENSMUSG00000021567	0.636229315311352	0.636229315311352	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495
Ctnnd2	ENSMUSG00000022240	0.395562602091096	0.455625354715448	0.454600801949285	0.455625354715448	0.455625354715448	0.455625354715448
Lrp5	ENSMUSG00000024913	0.509144723230069	0.763717084845103	0.21549027811633	0.64647083434899	0.776919261684345	0.776919261684345
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Vangl1	ENSMUSG00000027860	0.213672724643676	0.294439684556453	0.213672724643677	0.294439684556453	0.294439684556453	0.294439684556453
Dkk2	ENSMUSG00000028031	0.781011212316137	0.926604389137101	0.00038022066409592	0.00114066199228776	0.926604389137101	0.926604389137101
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Ctnnbip1	ENSMUSG00000028988	0.255901190956604	0.383851786434906	0.146800541856249	0.383851786434906	0.853694531487825	0.853694531487825
Cul1	ENSMUSG00000029686	0.514934023620345	0.514934023620345	0.347639524025037	0.514934023620345	0.514300775319626	0.514934023620345
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Gpc4	ENSMUSG00000031119	0.0241933715424143	0.0725801146272428	0.214037080764326	0.321055621146489	0.456305241393103	0.456305241393103
Sfrp1	ENSMUSG00000031548	0.347639524025037	0.521459286037555	0.179945789077372	0.521459286037555	0.710208797518812	0.710208797518812
Nkd1	ENSMUSG00000031661	0.926441990075769	0.926441990075769	0.120850531362929	0.181275797044394	0.0763619660358786	0.181275797044394
Prickle1	ENSMUSG00000036158	0.454942951775342	0.454942951775342	0.0964252305385472	0.179446626251387	0.119631084167592	0.179446626251387
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Ctbp1	ENSMUSG00000037373	0.00463747559282087	0.0139124267784626	0.044737329683373	0.0671059945250595	0.643853282854191	0.643853282854191
Daam2	ENSMUSG00000040260	0.576973746230334	0.852065168704833	0.0761127945805735	0.228338383741721	0.852065168704833	0.852065168704833
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Prickle4	ENSMUSG00000096549	0.203297129862076	0.304945694793114	0.0320312337221707	0.096093701166512	0.636491364335909	0.636491364335909

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Gap junction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Tubb5	ENSMUSG00000001525	0.00037335518005407	0.00112006554016221	0.0171027900598199	0.0256541850897299	0.0761127945805735	0.0761127945805735
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Adrb1	ENSMUSG00000035283	0.781170242226513	1	0.346899083932133	1	1	1
Tubb4b	ENSMUSG00000036752	0.0116356061791785	0.0349068185375355	0.179945789077372	0.269918683616058	0.781170242226513	0.781170242226513
Gucy1a2	ENSMUSG00000041624	0.78148726569172	0.78148726569172	0.640355507848752	0.78148726569172	0.643359829732651	0.78148726569172
Tuba1c	ENSMUSG00000043091	0.514934023620344	0.926550375688041	0.926550375688041	0.926550375688041	0.853694531487825	0.926550375688041
Gja1	ENSMUSG00000050953	0.853694531487825	0.853694531487825	0.0451153644990944	0.135346093497283	0.78180291566155	0.853694531487825
Map2k5	ENSMUSG00000058444	0.148115998140415	0.264150874616835	0.17610058307789	0.264150874616835	1	1
Tubb4a	ENSMUSG00000062591	0.640861491578951	0.78148726569172	0.174692232033629	0.524076696100888	0.78148726569172	0.78148726569172

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Endocrine resistance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Cdkn2c	ENSMUSG00000028551	0.0164739112492867	0.0360931285010865	0.024062085667391	0.0360931285010865	0.148772260628989	0.148772260628989
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Notch3	ENSMUSG00000038146	0.178901132102685	0.446772960955053	0.297848640636702	0.446772960955053	0.643359829732651	0.643359829732651
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Relaxin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Mmp13	ENSMUSG00000050578	0.177153312234059	0.531459936702178	0.398108175780842	0.597162263671263	0.853801250889739	0.853801250889739
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343

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Hippo signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bbc3	ENSMUSG00000002083	0.347639524025037	0.670898993600072	0.447265995733381	0.670898993600072	0.708534948098331	0.708534948098331
Bmp8b	ENSMUSG00000002384	0.208897379073412	0.626692137220235	1	1	0.708745765211584	1
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Ppp2r1a	ENSMUSG00000007564	0.00289311433957183	0.00867934301871548	0.01710279005982	0.0256541850897299	0.78180291566155	0.78180291566155
Bmp7	ENSMUSG00000008999	0.256271555563966	0.384407333345949	0.252920381501207	0.384407333345949	0.708534948098331	0.708534948098331
Nf2	ENSMUSG00000009073	0.643853282854191	0.926441990075769	0.642366752097095	0.926441990075769	0.926441990075769	0.926441990075769
Ywhab	ENSMUSG00000018326	0.450444934184774	0.450444934184774	0.0566379395854603	0.10856844153961	0.0723789610264069	0.10856844153961
Ctgf	ENSMUSG00000019997	0.148115998140416	0.222173997210623	0.120850531362929	0.222173997210623	0.399548817627028	0.399548817627028
Fbxw11	ENSMUSG00000020271	0.346899083932133	0.575536202757516	0.575536202757516	0.575536202757516	0.514300775319626	0.575536202757516
Nkd2	ENSMUSG00000021567	0.636229315311352	0.636229315311352	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495
Ajuba	ENSMUSG00000022178	0.00468160475316414	0.0140448142594924	0.0328221470541517	0.0492332205812275	0.641867098978197	0.641867098978197
Pard3	ENSMUSG00000025812	0.781170242226513	0.781170242226513	0.711034989117171	0.781170242226513	0.513026869856283	0.781170242226513
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Nkd1	ENSMUSG00000031661	0.926441990075769	0.926441990075769	0.120850531362929	0.181275797044394	0.0763619660358786	0.181275797044394
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Serpine1	ENSMUSG00000037411	0.344663224299303	0.344663224299303	0.342405296020881	0.344663224299303	0.142165951159432	0.344663224299303
Bmp6	ENSMUSG00000039004	0.0766111619812296	0.144637845807821	0.0964252305385471	0.144637845807821	0.348008842235184	0.348008842235184
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Ywhag	ENSMUSG00000051391	0.11993617140438	0.181732522866545	0.121155015244363	0.181732522866545	0.852065168704833	0.852065168704833
Yap1	ENSMUSG00000053110	0.514617706526787	0.77192655979018	0.0163700297194362	0.0491100891583087	0.781645261743309	0.781645261743309
Pard6g	ENSMUSG00000056214	0.112265881554681	0.168398822332022	0.00130806497567845	0.00392419492703534	0.643853282854191	0.643853282854191
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Lysosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Psap	ENSMUSG00000004207	0.00161470887631956	0.00484412662895869	0.0113089139751576	0.0169633709627364	0.92622377157404	0.92622377157404
Ap1s1	ENSMUSG00000004849	0.144157978128026	0.220200812784373	0.146800541856249	0.220200812784373	0.926550375688041	0.926550375688041
Hyal2	ENSMUSG00000010047	0.0232795908282423	0.0698387724847269	0.21549027811633	0.323235417174496	0.643359829732651	0.643359829732651
Ppt2	ENSMUSG00000015474	0.300095920620218	0.450143880930327	0.120545895661628	0.361637686984883	1	1
Atp6ap1	ENSMUSG00000019087	0.204424977646738	0.204424977646738	0.0969812105731562	0.145471815859734	0.00429270217529417	0.0128781065258825
Galc	ENSMUSG00000021003	0.514934023620345	0.772401035430517	0.177153312234059	0.531459936702178	0.851732715229127	0.851732715229127
Ctsb	ENSMUSG00000021939	0.148772260628989	0.44337167859054	0.29558111906036	0.44337167859054	0.453225835454266	0.453225835454266
Naga	ENSMUSG00000022453	0.0325051220296005	0.0975153660888015	0.711034989117171	1	1	1
Nagpa	ENSMUSG00000023143	0.211844580334808	0.516994836448954	0.344663224299303	0.516994836448954	1	1
Atp6v0c	ENSMUSG00000024121	0.148115998140415	0.222173997210623	0.058823267388015	0.176469802164045	0.45596561163947	0.45596561163947
Hexa	ENSMUSG00000025232	0.146800541856249	0.220200812784373	0.044926265292481	0.134778795877443	0.294820734456232	0.294820734456232
Gusb	ENSMUSG00000025534	0.00289311433957183	0.00867934301871549	0.5155648232968	0.5155648232968	0.146141353215796	0.219212029823693
Gaa	ENSMUSG00000025579	0.214037080764326	0.321055621146489	0.211110344399808	0.321055621146489	1	1
Slc11a1	ENSMUSG00000026177	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.782117202022501	0.782117202022501
Ctso	ENSMUSG00000028015	0.643853282854191	0.78180291566155	0.78180291566155	0.78180291566155	0.0761127945805735	0.228338383741721
Sumf1	ENSMUSG00000030101	0.146141353215796	0.298599969973532	0.298599969973532	0.298599969973532	0.213307944885796	0.298599969973532
Cln3	ENSMUSG00000030720	0.0723789610264069	0.10856844153961	0.0434194723707707	0.10856844153961	0.293293089483362	0.293293089483362
Lamp1	ENSMUSG00000031447	0.577259514257969	0.577259514257969	0.297095062262362	0.445642593393544	0.146141353215796	0.438424059647387
Aga	ENSMUSG00000031521	0.348008842235184	0.522013263352777	0.781170242226513	0.781170242226513	0.0116356061791785	0.0349068185375355
Pla2g15	ENSMUSG00000031903	0.0163700297194362	0.0245550445791543	0.00159435459956481	0.00478306379869443	0.640608766263372	0.640608766263372
Gga1	ENSMUSG00000033128	0.0919695072173338	0.275908521652001	0.453570536021945	0.680355804032917	0.85117361048289	0.85117361048289
Smpd1	ENSMUSG00000037049	0.024062085667391	0.0360931285010865	0.00768144932639892	0.0230443479791968	0.853801250889739	0.853801250889739
Ap1g2	ENSMUSG00000040701	0.0325051220296004	0.0975153660888012	0.0947558980989551	0.142133847148433	0.643359829732651	0.643359829732651
Cltb	ENSMUSG00000047547	0.711034989117171	0.712057867818062	0.712057867818062	0.712057867818062	0.577829325134931	0.712057867818062

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Protein processing in endoplasmic reticulum

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkcsh	ENSMUSG00000003402	0.0434194723707708	0.0651292085561563	0.0168921052924602	0.0506763158773805	0.400265374208515	0.400265374208515
Rad23a	ENSMUSG00000003813	0.119936171404379	0.179904257106569	0.0947558980989549	0.179904257106569	0.572616808177226	0.572616808177226
Ubqln1	ENSMUSG00000005312	0.578113371816017	0.853694531487825	0.255901190956604	0.767703572869812	0.853694531487825	0.853694531487825
Ubqln4	ENSMUSG00000008604	0.148772260628989	0.223158390943484	0.148772260628989	0.223158390943484	1	1
Ube2g2	ENSMUSG00000009293	0.453225835454266	0.679838753181399	0.148115998140415	0.444347994421246	0.852832278580641	0.852832278580641
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Rnf185	ENSMUSG00000020448	0.0325051220296005	0.0862661421438878	0.0575107614292585	0.0862661421438878	0.348008842235184	0.348008842235184
Lman2	ENSMUSG00000021484	0.348008842235184	0.514934023620344	0.514934023620344	0.514934023620344	0.399548817627028	0.514934023620344
Ngly1	ENSMUSG00000021785	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773	0.640861491578951	0.640861491578951
Ube2j2	ENSMUSG00000023286	0.246478961478169	0.369718442217254	0.178901132102685	0.369718442217254	0.636229315311352	0.636229315311352
Hsp90ab1	ENSMUSG00000023944	0.148115998140416	0.270960820366545	0.18064054691103	0.270960820366545	0.781170242226513	0.781170242226513
Ddit3	ENSMUSG00000025408	0.0763619660358786	0.229085898107636	0.853694531487825	0.853694531487825	0.575824878403157	0.853694531487825
Rpn2	ENSMUSG00000027642	0.0115535350288052	0.0346606050864155	0.0592616003460512	0.0888924005190768	0.710001140920767	0.710001140920767
Vcp	ENSMUSG00000028452	0.0113089139751576	0.0256541850897299	0.01710279005982	0.0256541850897299	0.456305241393103	0.456305241393103
Eif2ak1	ENSMUSG00000029613	0.346527959006435	0.519791938509652	0.173632433887832	0.519791938509652	0.925444427431699	0.925444427431699
Cul1	ENSMUSG00000029686	0.514934023620345	0.514934023620345	0.347639524025037	0.514934023620345	0.514300775319626	0.514934023620345
Mogs	ENSMUSG00000030036	0.0171027900598199	0.0513083701794597	0.0964252305385472	0.144637845807821	0.347639524025037	0.347639524025037
Sec61a1	ENSMUSG00000030082	0.0964252305385469	0.289275691615641	0.578113371816017	0.711034989117171	0.711034989117171	0.711034989117171
Man1b1	ENSMUSG00000036646	0.0449262652924809	0.0673893979387214	0.0334587898203823	0.0673893979387214	0.454600801949285	0.454600801949285
Man1c1	ENSMUSG00000037306	0.300095920620218	0.450143880930327	0.0746183450292887	0.223855035087866	0.926550375688041	0.926550375688041
Edem2	ENSMUSG00000038312	0.21549027811633	0.323235417174495	0.0334587898203823	0.100376369461147	0.7802108304765	0.7802108304765
Wfs1	ENSMUSG00000039474	0.144820068500793	0.21723010275119	0.144820068500793	0.21723010275119	0.775217051297351	0.775217051297351
Stub1	ENSMUSG00000039615	0.511097249598474	0.511097249598474	0.00446325197783099	0.013389755933493	0.291756209988535	0.437634314982803
Ppp1r15a	ENSMUSG00000040435	0.454600801949285	0.454600801949285	0.0958690133561599	0.28760704006848	0.347639524025037	0.454600801949285
Bag2	ENSMUSG00000042215	0.78180291566155	0.78180291566155	0.642366752097095	0.78180291566155	0.712057867818062	0.78180291566155
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Ubqln2	ENSMUSG00000050148	0.121155015244363	0.181732522866545	0.0953125666339397	0.181732522866545	0.336273664439462	0.336273664439462
Hspa2	ENSMUSG00000059970	0.576973746230334	0.576973746230334	0.0579478375430677	0.173843512629203	0.255901190956604	0.383851786434906

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Adrenergic signaling in cardiomyocytes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Ppp2r1a	ENSMUSG00000007564	0.00289311433957183	0.00867934301871548	0.01710279005982	0.0256541850897299	0.78180291566155	0.78180291566155
Kcnq1	ENSMUSG00000009545	0.254414773803597	0.381622160705395	0.0743693776059065	0.223108132817719	0.781170242226513	0.781170242226513
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Ppp2r5c	ENSMUSG00000017843	0.399548817627028	0.599323226440542	0.119936171404379	0.359808514213138	0.852832278580641	0.852832278580641
Scn1b	ENSMUSG00000019194	0.120850531362929	0.181275797044394	0.0113901882503033	0.0341705647509099	0.453225835454266	0.453225835454266
Cacnb1	ENSMUSG00000020882	0.119631084167592	0.179446626251388	0.0964252305385473	0.179446626251388	0.926550375688041	0.926550375688041
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Tnnt2	ENSMUSG00000026414	0.347639524025037	0.347639524025037	0.058823267388015	0.176469802164045	0.216214347033995	0.324321520550992
Ppp2r5a	ENSMUSG00000026626	0.338976281569376	0.338976281569376	0.138156294413154	0.207234441619731	0.0432318933800775	0.129695680140233
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Tpm2	ENSMUSG00000028464	0.853801250889739	0.853801250889739	0.00283103937188884	0.00849311811566651	0.214037080764326	0.321055621146489
Slc8a2	ENSMUSG00000030376	0.709793037667153	0.709793037667153	0.032663525449452	0.0979905763483559	0.119631084167592	0.179446626251387
Tpm1	ENSMUSG00000032366	0.249528554620971	0.249528554620971	0.248769231421035	0.249528554620971	0.21549027811633	0.249528554620971
Adrb1	ENSMUSG00000035283	0.781170242226513	1	0.346899083932133	1	1	1
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Atp1b2	ENSMUSG00000041329	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062	0.642864324224729	0.712057867818062
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Adra1b	ENSMUSG00000050541	0.395928178642446	0.593892267963669	0.71082910328023	0.71082910328023	0.17855224077719	0.535656722331571
Myh7	ENSMUSG00000053093	0.575536202757516	0.575536202757516	0.120850531362929	0.362551594088788	0.345410946355104	0.518116419532656

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Cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mcm2	ENSMUSG00000002870	0.00768144932639896	0.0230443479791969	0.216214347033995	0.216214347033995	0.180293335960318	0.216214347033995
Zbtb17	ENSMUSG00000006215	0.0443599545252852	0.133079863575856	0.214037080764326	0.321055621146488	0.926658283600152	0.926658283600152
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
Ywhab	ENSMUSG00000018326	0.450444934184774	0.450444934184774	0.0566379395854603	0.10856844153961	0.0723789610264069	0.10856844153961
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Mcm6	ENSMUSG00000026355	0.00649065913668483	0.0194719774100545	0.511742979522636	0.511742979522636	0.345037391052887	0.511742979522636
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Cdkn2c	ENSMUSG00000028551	0.0164739112492867	0.0360931285010865	0.024062085667391	0.0360931285010865	0.148772260628989	0.148772260628989
Anapc7	ENSMUSG00000029466	0.0113089139751576	0.0339267419254727	0.299349060054895	0.449023590082343	0.643359829732651	0.643359829732651
Mad1l1	ENSMUSG00000029554	0.252920381501206	0.379380572251809	0.179945789077372	0.379380572251809	0.851954599472143	0.851954599472143
Cul1	ENSMUSG00000029686	0.514934023620345	0.514934023620345	0.347639524025037	0.514934023620345	0.514300775319626	0.514934023620345
Plk1	ENSMUSG00000030867	0.0583853430099097	0.175156029029729	0.216214347033995	0.324321520550992	0.853372965654504	0.853372965654504
Ccnb2	ENSMUSG00000032218	0.0953125666339397	0.181275797044394	0.120850531362929	0.181275797044394	0.642366752097095	0.642366752097095
Gadd45a	ENSMUSG00000036390	0.926550375688041	0.926550375688041	0.119936171404379	0.319961917328694	0.213307944885796	0.319961917328694
Cdkn1c	ENSMUSG00000037664	0.39335551479284	0.59003327218926	0.120850531362929	0.362551594088788	0.781960228679124	0.781960228679124
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Mcm3	ENSMUSG00000041859	0.00283103937188883	0.0084931181156665	0.255901190956604	0.255901190956604	0.120850531362929	0.181275797044394
Ywhag	ENSMUSG00000051391	0.11993617140438	0.181732522866545	0.121155015244363	0.181732522866545	0.852065168704833	0.852065168704833
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Cdkn2b	ENSMUSG00000073802	0.0158546704257246	0.0475640112771739	0.144820068500793	0.216214347033995	0.216214347033995	0.216214347033995

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cGMP-PKG signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Gna12	ENSMUSG00000000149	0.0964252305385471	0.144637845807821	0.0315593554855452	0.0946780664566357	0.635703516568382	0.635703516568382
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Mrvi1	ENSMUSG00000005611	0.775217051297351	0.852175490580835	0.0763619660358786	0.229085898107636	0.852175490580835	0.852175490580835
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Ppif	ENSMUSG00000021868	0.255901190956604	0.446772960955053	0.297848640636702	0.446772960955053	0.853801250889739	0.853801250889739
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Mylk	ENSMUSG00000022836	0.392985378348026	0.392985378348026	0.148115998140415	0.392985378348026	0.347639524025037	0.392985378348026
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Rgs2	ENSMUSG00000026360	0.120545895661628	0.295581119060361	0.295581119060361	0.295581119060361	0.248769231421035	0.295581119060361
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Slc8a2	ENSMUSG00000030376	0.709793037667153	0.709793037667153	0.032663525449452	0.0979905763483559	0.119631084167592	0.179446626251387
Vasp	ENSMUSG00000030403	0.000701972248021392	0.00210591674406418	0.044926265292481	0.0673893979387215	0.343537039781257	0.343537039781257
Trpc6	ENSMUSG00000031997	0.576687400573867	0.85326530496423	0.00286197841113335	0.00858593523340004	0.85326530496423	0.85326530496423
Adra2a	ENSMUSG00000033717	0.711034989117171	0.711034989117171	0.577829325134931	0.711034989117171	0.643853282854191	0.711034989117171
Adrb1	ENSMUSG00000035283	0.781170242226513	1	0.346899083932133	1	1	1
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Atp1b2	ENSMUSG00000041329	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062	0.642864324224729	0.712057867818062
Gucy1a2	ENSMUSG00000041624	0.78148726569172	0.78148726569172	0.640355507848752	0.78148726569172	0.643359829732651	0.78148726569172
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Adora1	ENSMUSG00000042429	0.00463747559282087	0.0139124267784626	0.844188605458011	0.844188605458011	0.142498552923913	0.21374782938587
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Adra1b	ENSMUSG00000050541	0.395928178642446	0.593892267963669	0.71082910328023	0.71082910328023	0.17855224077719	0.535656722331571
Myh7	ENSMUSG00000053093	0.575536202757516	0.575536202757516	0.120850531362929	0.362551594088788	0.345410946355104	0.518116419532656
Gtf2i	ENSMUSG00000060261	0.0117179415987428	0.0351538247962283	0.0331400397096515	0.0497100595644772	0.348008842235184	0.348008842235184

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Prostate cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hsp90ab1	ENSMUSG00000023944	0.148115998140416	0.270960820366545	0.18064054691103	0.270960820366545	0.781170242226513	0.781170242226513
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Spint1	ENSMUSG00000027315	0.119936171404379	0.179904257106569	0.0947558980989551	0.179904257106569	0.454600801949285	0.454600801949285
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Plat	ENSMUSG00000031538	0.0969812105731561	0.290943631719468	0.635703516568382	0.635703516568382	0.338976281569376	0.508464422354065
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Erg	ENSMUSG00000040732	0.926550375688041	0.926550375688041	0.344663224299303	0.926550375688041	0.851954599472143	0.926550375688041
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Platelet activation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Mylk	ENSMUSG00000022836	0.392985378348026	0.392985378348026	0.148115998140415	0.392985378348026	0.347639524025037	0.392985378348026
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Tbxas1	ENSMUSG00000029925	0.0964252305385471	0.219212029823693	0.146141353215796	0.219212029823693	0.643853282854191	0.643853282854191
Vasp	ENSMUSG00000030403	0.000701972248021392	0.00210591674406418	0.044926265292481	0.0673893979387215	0.343537039781257	0.343537039781257
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Gucy1a2	ENSMUSG00000041624	0.78148726569172	0.78148726569172	0.640355507848752	0.78148726569172	0.643359829732651	0.78148726569172
Ptgir	ENSMUSG00000043017	0.0432318933800775	0.129695680140233	0.513665062682276	0.770497594023414	0.782117202022501	0.782117202022501
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Pla2g4f	ENSMUSG00000046971	0.0409950409136847	0.122985122741054	0.512386180848416	0.512386180848416	0.296339225025931	0.444508837538896
Orai1	ENSMUSG00000049686	0.513665062682275	0.711240436189781	0.345037391052887	0.711240436189781	0.711240436189781	0.711240436189781
Tln2	ENSMUSG00000052698	0.146800541856249	0.440401625568746	0.710001140920767	0.852504981253341	0.852504981253341	0.852504981253341
PLA2G4B	ENSMUSG00000098488	0.505838378028518	0.758757567042777	0.9255572759333	0.9255572759333	0.453225835454266	0.758757567042777

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Oxytocin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Cacnb1	ENSMUSG00000020882	0.119631084167592	0.179446626251388	0.0964252305385473	0.179446626251388	0.926550375688041	0.926550375688041
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Mylk	ENSMUSG00000022836	0.392985378348026	0.392985378348026	0.148115998140415	0.392985378348026	0.347639524025037	0.392985378348026
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Rgs2	ENSMUSG00000026360	0.120545895661628	0.295581119060361	0.295581119060361	0.295581119060361	0.248769231421035	0.295581119060361
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Kcnj5	ENSMUSG00000032034	0.926604389137101	0.926604389137101	0.0332993082165205	0.0998979246495616	0.643606811957488	0.926604389137101
Eef2	ENSMUSG00000034994	0.0969812105731562	0.181275797044394	0.120850531362929	0.181275797044394	0.348008842235184	0.348008842235184
Kcnj9	ENSMUSG00000038026	0.255158975839805	0.255158975839805	0.17924968721805	0.255158975839805	0.0328221470541517	0.098466441162455
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Gucy1a2	ENSMUSG00000041624	0.78148726569172	0.78148726569172	0.640355507848752	0.78148726569172	0.643359829732651	0.78148726569172
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Pla2g4f	ENSMUSG00000046971	0.0409950409136847	0.122985122741054	0.512386180848416	0.512386180848416	0.296339225025931	0.444508837538896
Map2k5	ENSMUSG00000058444	0.148115998140415	0.264150874616835	0.17610058307789	0.264150874616835	1	1
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
PLA2G4B	ENSMUSG00000098488	0.505838378028518	0.758757567042777	0.9255572759333	0.9255572759333	0.453225835454266	0.758757567042777

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Rap1 signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Ngfr	ENSMUSG00000000120	0.297848640636702	0.446772960955053	0.297848640636702	0.446772960955053	0.853801250889739	0.853801250889739
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Tiam1	ENSMUSG00000002489	0.120850531362929	0.362551594088788	0.92622377157404	0.92622377157404	0.643359829732651	0.92622377157404
Ralb	ENSMUSG00000004451	0.119936171404379	0.359808514213138	0.455625354715449	0.455625354715449	0.399548817627028	0.455625354715449
Tek	ENSMUSG00000006386	0.11993617140438	0.179904257106569	0.0964252305385472	0.179904257106569	0.853801250889739	0.853801250889739
Map2k3	ENSMUSG00000018932	0.0325051220296005	0.0975153660888015	0.300095920620218	0.344663224299303	0.344663224299303	0.344663224299303
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Pard3	ENSMUSG00000025812	0.781170242226513	0.781170242226513	0.711034989117171	0.781170242226513	0.513026869856283	0.781170242226513
Grin1	ENSMUSG00000026959	0.21549027811633	0.323235417174495	0.0969812105731562	0.290943631719469	0.400265374208515	0.400265374208515
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Pfn2	ENSMUSG00000027805	0.576973746230334	0.852832278580641	0.0703913497478892	0.211174049243668	0.852832278580641	0.852832278580641
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Flt1	ENSMUSG00000029648	0.45596561163947	0.513665062682276	0.148115998140416	0.444347994421247	0.513665062682276	0.513665062682276
Vasp	ENSMUSG00000030403	0.000701972248021392	0.00210591674406418	0.044926265292481	0.0673893979387215	0.343537039781257	0.343537039781257
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Ctnnd1	ENSMUSG00000034101	0.21549027811633	0.64647083434899	0.777922216623952	0.85117361048289	0.85117361048289	0.85117361048289
Dock4	ENSMUSG00000035954	0.926496242814507	0.926496242814507	0.299722768420014	0.899168305260041	0.711034989117171	0.926496242814507
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Tln2	ENSMUSG00000052698	0.146800541856249	0.440401625568746	0.710001140920767	0.852504981253341	0.852504981253341	0.852504981253341
Pard6g	ENSMUSG00000056214	0.112265881554681	0.168398822332022	0.00130806497567845	0.00392419492703534	0.643853282854191	0.643853282854191
Grin2a	ENSMUSG00000059003	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095	0.575536202757516	0.642366752097095
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513

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p53 signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bbc3	ENSMUSG00000002083	0.347639524025037	0.670898993600072	0.447265995733381	0.670898993600072	0.708534948098331	0.708534948098331
Igfbp3	ENSMUSG00000020427	0.399548817627028	0.399548817627028	0.0575107614292585	0.172532284287776	0.297848640636702	0.399548817627028
Rrm2	ENSMUSG00000020649	0.0763619660358787	0.229085898107636	0.216214347033995	0.324321520550992	0.577259514257969	0.577259514257969
Gtse1	ENSMUSG00000022385	0.00768144932639892	0.0230443479791968	0.0953125666339396	0.142968849950909	0.642366752097095	0.642366752097095
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Steap3	ENSMUSG00000026389	0.0451153644990944	0.135346093497283	0.11595859961889	0.173937899428335	0.388491809581663	0.388491809581663
Sesn2	ENSMUSG00000028893	0.643606811957488	0.643606811957488	0.398469281729516	0.597703922594274	0.0950342596054054	0.285102778816216
Ccnb2	ENSMUSG00000032218	0.0953125666339397	0.181275797044394	0.120850531362929	0.181275797044394	0.642366752097095	0.642366752097095
Gadd45a	ENSMUSG00000036390	0.926550375688041	0.926550375688041	0.119936171404379	0.319961917328694	0.213307944885796	0.319961917328694
Serpine1	ENSMUSG00000037411	0.344663224299303	0.344663224299303	0.342405296020881	0.344663224299303	0.142165951159432	0.344663224299303
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Rfwd2	ENSMUSG00000040782	0.7802108304765	0.7802108304765	0.00153425095635555	0.00460275286906664	0.0168921052924602	0.0253381579386903
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ei24	ENSMUSG00000062762	0.509798138101151	0.509798138101151	0.216214347033995	0.324321520550992	0.213307944885796	0.324321520550992
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Dopaminergic synapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Ppp2r1a	ENSMUSG00000007564	0.00289311433957183	0.00867934301871548	0.01710279005982	0.0256541850897299	0.78180291566155	0.78180291566155
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Ppp2r5c	ENSMUSG00000017843	0.399548817627028	0.599323226440542	0.119936171404379	0.359808514213138	0.852832278580641	0.852832278580641
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Maoa	ENSMUSG00000025037	0.513026869856283	0.638824656785692	0.637274134311157	0.638824656785692	0.638824656785692	0.638824656785692
Ppp2r5a	ENSMUSG00000026626	0.338976281569376	0.338976281569376	0.138156294413154	0.207234441619731	0.0432318933800775	0.129695680140233
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Kcnj5	ENSMUSG00000032034	0.926604389137101	0.926604389137101	0.0332993082165205	0.0998979246495616	0.643606811957488	0.926604389137101
Kcnj9	ENSMUSG00000038026	0.255158975839805	0.255158975839805	0.17924968721805	0.255158975839805	0.0328221470541517	0.098466441162455
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Grin2a	ENSMUSG00000059003	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095	0.575536202757516	0.642366752097095
Ppp1r1b	ENSMUSG00000061718	0.0592616003460511	0.177784801038153	0.177853449259986	0.266780173889979	0.513665062682276	0.513665062682276
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343

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Pathways in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Gna12	ENSMUSG00000000149	0.0964252305385471	0.144637845807821	0.0315593554855452	0.0946780664566357	0.635703516568382	0.635703516568382
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Txnrd3	ENSMUSG00000000811	0.00270924971713392	0.00812774915140177	0.0947558980989549	0.0947558980989549	0.0756145297453649	0.0947558980989549
Jup	ENSMUSG00000001552	0.118714930081337	0.35614479024401	0.509798138101151	0.764697207151727	0.852065168704833	0.852065168704833
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Bbc3	ENSMUSG00000002083	0.347639524025037	0.670898993600072	0.447265995733381	0.670898993600072	0.708534948098331	0.708534948098331
Shh	ENSMUSG00000002633	0.779564169324888	0.779564169324888	0.0575107614292585	0.172532284287776	0.570237634273406	0.779564169324888
Ralb	ENSMUSG00000004451	0.119936171404379	0.359808514213138	0.455625354715449	0.455625354715449	0.399548817627028	0.455625354715449
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Zbtb17	ENSMUSG00000006215	0.0443599545252852	0.133079863575856	0.214037080764326	0.321055621146488	0.926658283600152	0.926658283600152
Epor	ENSMUSG00000006235	0.00153425095635554	0.00460275286906663	0.0445485589872461	0.0668228384808692	0.344288444541856	0.344288444541856
Bcr	ENSMUSG00000009681	0.5155648232968	0.712057867818062	0.711854160331342	0.712057867818062	0.712057867818062	0.712057867818062
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Txnrd1	ENSMUSG00000020250	0.456305241393103	0.576112968612194	0.297848640636703	0.576112968612194	0.576112968612194	0.576112968612194
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Hes1	ENSMUSG00000022528	0.710208797518812	0.710208797518812	0.148115998140416	0.444347994421247	0.345037391052887	0.51755608657933
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Ifngr2	ENSMUSG00000022965	0.398108175780842	0.573791743469336	0.11993617140438	0.359808514213139	0.573791743469336	0.573791743469336
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hsp90ab1	ENSMUSG00000023944	0.148115998140416	0.270960820366545	0.18064054691103	0.270960820366545	0.781170242226513	0.781170242226513
Ralbp1	ENSMUSG00000024096	0.300095920620218	0.710208797518812	0.710208797518812	0.710208797518812	0.578113371816017	0.710208797518812
Msh2	ENSMUSG00000024151	0.024062085667391	0.0473390332283179	0.0315593554855452	0.0473390332283179	0.180293335960318	0.180293335960318
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Lrp5	ENSMUSG00000024913	0.509144723230069	0.763717084845103	0.21549027811633	0.64647083434899	0.776919261684345	0.776919261684345
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Gsto1	ENSMUSG00000025068	0.926003599371282	0.926003599371282	0.072378961026407	0.217136883079221	0.578113371816017	0.867170057724026
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Ntrk1	ENSMUSG00000028072	0.416823357713009	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596
Cul1	ENSMUSG00000029686	0.514934023620345	0.514934023620345	0.347639524025037	0.514934023620345	0.514300775319626	0.514934023620345
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Fadd	ENSMUSG00000031077	0.0449262652924809	0.134778795877443	0.119631084167592	0.179446626251387	0.7802108304765	0.7802108304765
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Egln1	ENSMUSG00000031987	0.782117202022501	0.782117202022501	0.121155015244363	0.363465045733089	0.5155648232968	0.7733472349452
Gsta4	ENSMUSG00000032348	0.0331400397096514	0.0994201191289543	0.636229315311352	0.636229315311352	0.214764523938594	0.322146785907891
Dapk3	ENSMUSG00000034974	0.781170242226513	0.926658283600152	0.09586901335616	0.28760704006848	0.926658283600152	0.926658283600152
Gadd45a	ENSMUSG00000036390	0.926550375688041	0.926550375688041	0.119936171404379	0.319961917328694	0.213307944885796	0.319961917328694
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Ctbp1	ENSMUSG00000037373	0.00463747559282087	0.0139124267784626	0.044737329683373	0.0671059945250595	0.643853282854191	0.643853282854191
Notch3	ENSMUSG00000038146	0.178901132102685	0.446772960955053	0.297848640636702	0.446772960955053	0.643359829732651	0.643359829732651
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Ptger3	ENSMUSG00000040016	0.78180291566155	0.78180291566155	0.454600801949285	0.681901202923927	0.0441715176243983	0.132514552873195
Hey1	ENSMUSG00000040289	0.344663224299303	0.344663224299303	0.120850531362929	0.222173997210623	0.148115998140416	0.222173997210623
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Ccdc6	ENSMUSG00000048701	0.45596561163947	0.772401035430517	0.514934023620345	0.772401035430517	1	1
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343
Cdkn2b	ENSMUSG00000073802	0.0158546704257246	0.0475640112771739	0.144820068500793	0.216214347033995	0.216214347033995	0.216214347033995

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Apelin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Ctgf	ENSMUSG00000019997	0.148115998140416	0.222173997210623	0.120850531362929	0.222173997210623	0.399548817627028	0.399548817627028
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Mylk	ENSMUSG00000022836	0.392985378348026	0.392985378348026	0.148115998140415	0.392985378348026	0.347639524025037	0.392985378348026
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Slc8a2	ENSMUSG00000030376	0.709793037667153	0.709793037667153	0.032663525449452	0.0979905763483559	0.119631084167592	0.179446626251387
Plat	ENSMUSG00000031538	0.0969812105731561	0.290943631719468	0.635703516568382	0.635703516568382	0.338976281569376	0.508464422354065
Apln	ENSMUSG00000037010	0.399548817627028	0.399548817627028	0.0746183450292888	0.223855035087866	0.211844580334808	0.317766870502212
Serpine1	ENSMUSG00000037411	0.344663224299303	0.344663224299303	0.342405296020881	0.344663224299303	0.142165951159432	0.344663224299303
Notch3	ENSMUSG00000038146	0.178901132102685	0.446772960955053	0.297848640636702	0.446772960955053	0.643359829732651	0.643359829732651
Aplnr	ENSMUSG00000044338	0.096425230538547	0.144637845807821	0.0168921052924602	0.0506763158773805	0.780851835278818	0.780851835278818
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Nrf1	ENSMUSG00000058440	0.119631084167592	0.358893252502775	1	1	0.342026805366747	0.51304020805012
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343

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Proteoglycans in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Tiam1	ENSMUSG00000002489	0.120850531362929	0.362551594088788	0.92622377157404	0.92622377157404	0.643359829732651	0.92622377157404
Shh	ENSMUSG00000002633	0.779564169324888	0.779564169324888	0.0575107614292585	0.172532284287776	0.570237634273406	0.779564169324888
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Tfap4	ENSMUSG00000005718	0.642117186565222	0.642117186565222	0.249907451332337	0.598784401330551	0.399189600887034	0.598784401330551
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
Timp3	ENSMUSG00000020044	0.78180291566155	0.78180291566155	0.120545895661628	0.324321520550992	0.216214347033994	0.324321520550992
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Itgb5	ENSMUSG00000022817	0.78180291566155	0.78180291566155	0.577829325134931	0.78180291566155	0.398108175780842	0.78180291566155
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Hspg2	ENSMUSG00000028763	0.0241933715424143	0.0487576830444007	0.0325051220296005	0.0487576830444007	0.256271555563966	0.256271555563966
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Pak1	ENSMUSG00000030774	0.0117179415987427	0.0351538247962282	0.399548817627028	0.399548817627028	0.142165951159432	0.213248926739148
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Gpc1	ENSMUSG00000034220	0.395196379647461	0.592794569471192	0.146800541856249	0.440401625568746	0.712057867818062	0.712057867818062
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Eif4b	ENSMUSG00000058655	0.21549027811633	0.383851786434905	0.255901190956604	0.383851786434905	0.642366752097095	0.642366752097095
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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PI3K-Akt signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ngfr	ENSMUSG00000000120	0.297848640636702	0.446772960955053	0.297848640636702	0.446772960955053	0.853801250889739	0.853801250889739
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Epor	ENSMUSG00000006235	0.00153425095635554	0.00460275286906663	0.0445485589872461	0.0668228384808692	0.344288444541856	0.344288444541856
Tek	ENSMUSG00000006386	0.11993617140438	0.179904257106569	0.0964252305385472	0.179904257106569	0.853801250889739	0.853801250889739
Ppp2r1a	ENSMUSG00000007564	0.00289311433957183	0.00867934301871548	0.01710279005982	0.0256541850897299	0.78180291566155	0.78180291566155
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
Ppp2r5c	ENSMUSG00000017843	0.399548817627028	0.599323226440542	0.119936171404379	0.359808514213138	0.852832278580641	0.852832278580641
Ywhab	ENSMUSG00000018326	0.450444934184774	0.450444934184774	0.0566379395854603	0.10856844153961	0.0723789610264069	0.10856844153961
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Gh	ENSMUSG00000020713	0.0736226835515671	0.220868050654701	0.629488615236542	0.774351207035292	0.774351207035292	0.774351207035292
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Osmr	ENSMUSG00000022146	0.779238691542963	0.779238691542963	0.346527959006434	0.519791938509652	0.208156293081417	0.519791938509652
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Itgb5	ENSMUSG00000022817	0.78180291566155	0.78180291566155	0.577829325134931	0.78180291566155	0.398108175780842	0.78180291566155
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Hsp90ab1	ENSMUSG00000023944	0.148115998140416	0.270960820366545	0.18064054691103	0.270960820366545	0.781170242226513	0.781170242226513
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Ppp2r5a	ENSMUSG00000026626	0.338976281569376	0.338976281569376	0.138156294413154	0.207234441619731	0.0432318933800775	0.129695680140233
Itgb6	ENSMUSG00000026971	0.926550375688041	0.926550375688041	0.0073134885581712	0.0219404656745136	0.454600801949285	0.681901202923927
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Ntrk1	ENSMUSG00000028072	0.416823357713009	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596
Them4	ENSMUSG00000028145	0.119631084167592	0.358893252502775	0.92622377157404	0.92622377157404	0.513665062682276	0.770497594023414
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Flt1	ENSMUSG00000029648	0.45596561163947	0.513665062682276	0.148115998140416	0.444347994421247	0.513665062682276	0.513665062682276
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Col6a4	ENSMUSG00000032572	0.044926265292481	0.0673893979387215	0.00481536616919077	0.0144460985075723	0.711854160331342	0.711854160331342
Mcl1	ENSMUSG00000038612	0.711650020253571	0.926441990075769	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Pik3r6	ENSMUSG00000046207	0.0164739112492867	0.0494217337478601	0.0334587898203823	0.0501881847305734	0.5155648232968	0.5155648232968
Ntf3	ENSMUSG00000049107	1	1	0.00289311433957183	0.00867934301871549	0.447621891168214	0.671432836752321
Ywhag	ENSMUSG00000051391	0.11993617140438	0.181732522866545	0.121155015244363	0.181732522866545	0.852065168704833	0.852065168704833
Eif4b	ENSMUSG00000058655	0.21549027811633	0.383851786434905	0.255901190956604	0.383851786434905	0.642366752097095	0.642366752097095
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343

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Various types of N-glycan biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hexa	ENSMUSG00000025232	0.146800541856249	0.220200812784373	0.044926265292481	0.134778795877443	0.294820734456232	0.294820734456232
Rpn2	ENSMUSG00000027642	0.0115535350288052	0.0346606050864155	0.0592616003460512	0.0888924005190768	0.710001140920767	0.710001140920767
St3gal3	ENSMUSG00000028538	0.781960228679124	0.781960228679124	0.00463747559282086	0.0139124267784626	0.347639524025037	0.521459286037555
Glt28d2	ENSMUSG00000031286	0.214037080764326	0.321055621146489	0.119631084167591	0.321055621146489	0.578396848531894	0.578396848531894
Alg3	ENSMUSG00000033809	0.345410946355104	0.7733472349452	0.5155648232968	0.7733472349452	0.782117202022501	0.782117202022501
Alg12	ENSMUSG00000035845	0.711240436189781	1	1	1	0.348008842235184	1
Man1b1	ENSMUSG00000036646	0.0449262652924809	0.0673893979387214	0.0334587898203823	0.0673893979387214	0.454600801949285	0.454600801949285
Man1c1	ENSMUSG00000037306	0.300095920620218	0.450143880930327	0.0746183450292887	0.223855035087866	0.926550375688041	0.926550375688041
Alg2	ENSMUSG00000039740	0.213307944885796	0.639923834657388	0.643359829732651	0.643359829732651	0.643359829732651	0.643359829732651
Chst8	ENSMUSG00000060402	0.096147151118103	0.180361663185052	0.298974794311434	0.298974794311434	0.120241108790035	0.180361663185052

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Focal adhesion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Ppp1cc	ENSMUSG00000004455	0.0421101560083838	0.0648478400701162	0.0432318933800774	0.0648478400701162	0.389247465657472	0.389247465657472
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Parvb	ENSMUSG00000022438	0.146471068967596	0.219706603451393	0.00472596298562399	0.014177888956872	0.711650020253571	0.711650020253571
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Itgb5	ENSMUSG00000022817	0.78180291566155	0.78180291566155	0.577829325134931	0.78180291566155	0.398108175780842	0.78180291566155
Mylk	ENSMUSG00000022836	0.392985378348026	0.392985378348026	0.148115998140415	0.392985378348026	0.347639524025037	0.392985378348026
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Itgb6	ENSMUSG00000026971	0.926550375688041	0.926550375688041	0.0073134885581712	0.0219404656745136	0.454600801949285	0.681901202923927
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Flt1	ENSMUSG00000029648	0.45596561163947	0.513665062682276	0.148115998140416	0.444347994421247	0.513665062682276	0.513665062682276
Vasp	ENSMUSG00000030403	0.000701972248021392	0.00210591674406418	0.044926265292481	0.0673893979387215	0.343537039781257	0.343537039781257
Pak1	ENSMUSG00000030774	0.0117179415987427	0.0351538247962282	0.399548817627028	0.399548817627028	0.142165951159432	0.213248926739148
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Col6a4	ENSMUSG00000032572	0.044926265292481	0.0673893979387215	0.00481536616919077	0.0144460985075723	0.711854160331342	0.711854160331342
Pak7	ENSMUSG00000039913	0.383124961266744	0.574687441900116	0.698780661278595	0.698780661278595	0.00892508641180896	0.0267752592354269
Thbs1	ENSMUSG00000040152	0.926658283600152	0.926658283600152	0.452880492349546	0.926658283600152	0.926333123228344	0.926658283600152
Ppp1ca	ENSMUSG00000040385	0.0171027900598199	0.0513083701794597	0.0763619660358786	0.114542949053818	0.852504981253341	0.852504981253341
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Tln2	ENSMUSG00000052698	0.146800541856249	0.440401625568746	0.710001140920767	0.852504981253341	0.852504981253341	0.852504981253341
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Protein digestion and absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Col18a1	ENSMUSG00000001435	0.399548817627028	0.599323226440542	0.0763619660358786	0.229085898107636	0.711854160331342	0.711854160331342
Kcnq1	ENSMUSG00000009545	0.254414773803597	0.381622160705395	0.0743693776059065	0.223108132817719	0.781170242226513	0.781170242226513
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Col14a1	ENSMUSG00000022371	0.343537039781257	0.515305559671886	0.024062085667391	0.072186257002173	0.711650020253571	0.711650020253571
Col11a2	ENSMUSG00000024330	0.0166824765447319	0.0500474296341957	0.92622377157404	0.92622377157404	0.0756145297453648	0.113421794618047
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Col15a1	ENSMUSG00000028339	0.058823267388015	0.0882349010820225	0.00743512899358789	0.0223053869807637	0.85117361048289	0.85117361048289
Slc8a2	ENSMUSG00000030376	0.709793037667153	0.709793037667153	0.032663525449452	0.0979905763483559	0.119631084167592	0.179446626251387
Slc7a9	ENSMUSG00000030492	0.92622377157404	0.92622377157404	0.118409250205154	0.355227750615461	0.643853282854191	0.92622377157404
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Ctrl	ENSMUSG00000031896	0.852940894477647	0.852940894477647	0.297848640636702	0.852940894477647	0.576112968612194	0.852940894477647
Col6a4	ENSMUSG00000032572	0.044926265292481	0.0673893979387215	0.00481536616919077	0.0144460985075723	0.711854160331342	0.711854160331342
Col16a1	ENSMUSG00000040690	0.297848640636702	0.446772960955053	0.0449262652924809	0.134778795877443	0.45596561163947	0.45596561163947
Atp1b2	ENSMUSG00000041329	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062	0.642864324224729	0.712057867818062
Kcnn4	ENSMUSG00000054342	0.00276975149305653	0.00415462723958479	0.00253244992826164	0.00415462723958479	0.390750658104794	0.390750658104794
Col13a1	ENSMUSG00000058806	0.711854160331342	0.711854160331342	0.0451153644990944	0.135346093497283	0.711854160331342	0.711854160331342
Col23a1	ENSMUSG00000063564	0.255901190956604	0.383851786434906	0.0964252305385474	0.289275691615642	1	1

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Glutamatergic synapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Dlgap1	ENSMUSG00000003279	0.0219958379984644	0.0659875139953931	0.709793037667153	0.709793037667153	0.574083973533718	0.709793037667153
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Shank3	ENSMUSG00000022623	0.926604389137101	0.926604389137101	0.174692232033629	0.524076696100887	0.781645261743309	0.926604389137101
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
Grin1	ENSMUSG00000026959	0.21549027811633	0.323235417174495	0.0969812105731562	0.290943631719469	0.400265374208515	0.400265374208515
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Ppp3ca	ENSMUSG00000028161	0.216214347033995	0.324321520550992	0.00477055016690543	0.0143116505007163	0.643853282854191	0.643853282854191
Grik4	ENSMUSG00000032017	0.216214347033995	0.648643041101984	0.853480389728993	0.853480389728993	0.514300775319626	0.771451162979439
Gls2	ENSMUSG00000044005	0.392243127063687	0.393724994268831	0.148115998140416	0.393724994268831	0.393724994268831	0.393724994268831
Pla2g4f	ENSMUSG00000046971	0.0409950409136847	0.122985122741054	0.512386180848416	0.512386180848416	0.296339225025931	0.444508837538896
Grin2a	ENSMUSG00000059003	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095	0.575536202757516	0.642366752097095
Grm4	ENSMUSG00000063239	0.142165951159432	0.426497853478296	0.298599969973533	0.447899954960299	0.450094379653806	0.450094379653806
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343
PLA2G4B	ENSMUSG00000098488	0.505838378028518	0.758757567042777	0.9255572759333	0.9255572759333	0.453225835454266	0.758757567042777

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Ras signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ngfr	ENSMUSG00000000120	0.297848640636702	0.446772960955053	0.297848640636702	0.446772960955053	0.853801250889739	0.853801250889739
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Tiam1	ENSMUSG00000002489	0.120850531362929	0.362551594088788	0.92622377157404	0.92622377157404	0.643359829732651	0.92622377157404
Ralb	ENSMUSG00000004451	0.119936171404379	0.359808514213138	0.455625354715449	0.455625354715449	0.399548817627028	0.455625354715449
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Tek	ENSMUSG00000006386	0.11993617140438	0.179904257106569	0.0964252305385472	0.179904257106569	0.853801250889739	0.853801250889739
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Ralbp1	ENSMUSG00000024096	0.300095920620218	0.710208797518812	0.710208797518812	0.710208797518812	0.578113371816017	0.710208797518812
Pdgfrb	ENSMUSG00000024620	0.0583853430099098	0.0875780145148646	0.044737329683373	0.0875780145148646	0.514934023620345	0.514934023620345
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Rgl1	ENSMUSG00000026482	0.348008842235185	0.522013263352777	0.0761127945805736	0.228338383741721	0.642366752097095	0.642366752097095
Grin1	ENSMUSG00000026959	0.21549027811633	0.323235417174495	0.0969812105731562	0.290943631719469	0.400265374208515	0.400265374208515
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Ntrk1	ENSMUSG00000028072	0.416823357713009	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596	0.551719094905596
Flt1	ENSMUSG00000029648	0.45596561163947	0.513665062682276	0.148115998140416	0.444347994421247	0.513665062682276	0.513665062682276
Pak1	ENSMUSG00000030774	0.0117179415987427	0.0351538247962282	0.399548817627028	0.399548817627028	0.142165951159432	0.213248926739148
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Fgfr1	ENSMUSG00000031565	0.708323672944427	0.708323672944427	0.096147151118103	0.218717092414064	0.145811394942709	0.218717092414064
Pak7	ENSMUSG00000039913	0.383124961266744	0.574687441900116	0.698780661278595	0.698780661278595	0.00892508641180896	0.0267752592354269
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Pla2g4f	ENSMUSG00000046971	0.0409950409136847	0.122985122741054	0.512386180848416	0.512386180848416	0.296339225025931	0.444508837538896
Ntf3	ENSMUSG00000049107	1	1	0.00289311433957183	0.00867934301871549	0.447621891168214	0.671432836752321
Grin2a	ENSMUSG00000059003	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095	0.575536202757516	0.642366752097095
Ksr2	ENSMUSG00000061578	0.512706838380219	0.640101714462795	0.453570536021945	0.640101714462795	0.640101714462795	0.640101714462795
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343
PLA2G4B	ENSMUSG00000098488	0.505838378028518	0.758757567042777	0.9255572759333	0.9255572759333	0.453225835454266	0.758757567042777

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Fluid shear stress and atherosclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pdgfb	ENSMUSG00000000489	0.0449262652924809	0.0879063802250105	0.0586042534833403	0.0879063802250105	0.0967032506702098	0.0967032506702098
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Pias4	ENSMUSG00000004934	0.120850531362929	0.362551594088788	1	1	0.395928178642446	0.593892267963669
Cyba	ENSMUSG00000006519	0.00033393694769998	0.00100181084309994	0.297472133192261	0.446208199788392	0.642117186565222	0.642117186565222
Sqstm1	ENSMUSG00000015837	0.17610058307789	0.52830174923367	0.513665062682276	0.711650020253571	0.711650020253571	0.711650020253571
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Hsp90ab1	ENSMUSG00000023944	0.148115998140416	0.270960820366545	0.18064054691103	0.270960820366545	0.781170242226513	0.781170242226513
Gsto1	ENSMUSG00000025068	0.926003599371282	0.926003599371282	0.072378961026407	0.217136883079221	0.578113371816017	0.867170057724026
Chuk	ENSMUSG00000025199	0.030001399289448	0.0900041978683439	0.778253541606068	0.778253541606068	0.344663224299303	0.516994836448954
Il1r1	ENSMUSG00000026072	0.851061028660105	0.851061028660105	0.146800541856249	0.424701993236134	0.283134662157423	0.424701993236134
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Plat	ENSMUSG00000031538	0.0969812105731561	0.290943631719468	0.635703516568382	0.635703516568382	0.338976281569376	0.508464422354065
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Cdh5	ENSMUSG00000031871	0.514934023620345	0.710208797518812	0.254414773803597	0.710208797518812	0.710208797518812	0.710208797518812
Gsta4	ENSMUSG00000032348	0.0331400397096514	0.0994201191289543	0.636229315311352	0.636229315311352	0.214764523938594	0.322146785907891
Gpc1	ENSMUSG00000034220	0.395196379647461	0.592794569471192	0.146800541856249	0.440401625568746	0.712057867818062	0.712057867818062
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Map2k5	ENSMUSG00000058444	0.148115998140415	0.264150874616835	0.17610058307789	0.264150874616835	1	1
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Kdr	ENSMUSG00000062960	0.0763619660358786	0.222173997210623	0.148115998140415	0.222173997210623	0.781170242226513	0.781170242226513
Ass1	ENSMUSG00000076441	0.0763619660358785	0.114542949053818	0.0592616003460512	0.114542949053818	0.708745765211584	0.708745765211584

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RNA transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Eif2b5	ENSMUSG00000003235	0.00289311433957183	0.00722304925378615	0.00481536616919077	0.00722304925378615	0.252545530864481	0.252545530864481
Eif1b	ENSMUSG00000006941	0.451840588205062	0.451840588205062	0.0756145297453649	0.226843589236095	0.390750658104794	0.451840588205062
Pabpc4	ENSMUSG00000011257	0.0113089139751576	0.0339267419254727	0.0315593554855452	0.0473390332283179	0.513026869856283	0.513026869856283
Ddx19a	ENSMUSG00000015023	0.254414773803597	0.450444934184774	0.398108175780842	0.450444934184774	0.450444934184774	0.450444934184774
Eef1a2	ENSMUSG00000016349	0.85326530496423	0.85326530496423	0.179597906187076	0.269396859280614	0.0761127945805735	0.22833838374172
Eif3d	ENSMUSG00000016554	0.024062085667391	0.072186257002173	0.178901132102685	0.268351698154027	0.297848640636702	0.297848640636702
Nup50	ENSMUSG00000016619	0.120850531362929	0.362551594088788	0.400265374208515	0.578113371816017	0.578113371816017	0.578113371816017
Gle1	ENSMUSG00000019715	0.254414773803597	0.446772960955053	0.452880492349546	0.452880492349546	0.297848640636702	0.446772960955053
Elac2	ENSMUSG00000020549	0.00761949030813566	0.022858470924407	0.298974794311434	0.448462191467151	0.710208797518812	0.710208797518812
Rangap1	ENSMUSG00000022391	0.0592616003460512	0.11416919187086	0.0761127945805735	0.11416919187086	0.782117202022501	0.782117202022501
Eif4a2	ENSMUSG00000022884	0.177153312234059	0.266780173889979	0.78180291566155	0.78180291566155	0.177853449259986	0.266780173889979
Paip1	ENSMUSG00000025451	0.18064054691103	0.270960820366546	0.0331400397096515	0.0994201191289544	0.5155648232968	0.5155648232968
Thoc3	ENSMUSG00000025872	0.643359829732651	0.643359829732651	0.256271555563966	0.643359829732651	0.643359829732651	0.643359829732651
Rae1	ENSMUSG00000027509	0.0171027900598199	0.0256541850897299	0.0115535350288052	0.0256541850897299	0.642366752097095	0.642366752097095
Ddx20	ENSMUSG00000027905	0.34837756124189	0.34837756124189	0.255530331334266	0.34837756124189	0.21549027811633	0.34837756124189
Thoc5	ENSMUSG00000034274	0.00768144932639895	0.0230443479791968	0.511097249598474	0.511097249598474	0.17750354896016	0.26625532344024
Rnps1	ENSMUSG00000034681	0.0328221470541517	0.098466441162455	0.216214347033995	0.324321520550992	0.643853282854191	0.643853282854191
Pabpc5	ENSMUSG00000034732	0.709375484777034	0.779564169324888	0.294058061261852	0.779564169324888	0.779564169324888	0.779564169324888
Aaas	ENSMUSG00000036678	0.00153425095635555	0.00460275286906664	0.175044824745981	0.180293335960318	0.180293335960318	0.180293335960318
Gemin5	ENSMUSG00000037275	0.119631084167592	0.317766870502212	0.575536202757516	0.575536202757516	0.211844580334808	0.317766870502212
Nup133	ENSMUSG00000039509	0.0117179415987428	0.0351538247962283	0.399548817627028	0.455625354715449	0.455625354715449	0.455625354715449
Eif3j2	ENSMUSG00000043424	0.254414773803597	0.682414427663012	0.711854160331342	0.711854160331342	0.454942951775342	0.682414427663012
Eif4g1	ENSMUSG00000045983	0.180293335960318	0.540880007880955	0.395196379647461	0.592794569471191	0.850151080737202	0.850151080737202
Eif3b	ENSMUSG00000056076	0.454600801949285	0.681901202923927	0.395928178642446	0.681901202923927	0.926550375688041	0.926550375688041
Eif4b	ENSMUSG00000058655	0.21549027811633	0.383851786434905	0.255901190956604	0.383851786434905	0.642366752097095	0.642366752097095
Eif2s3y	ENSMUSG00000069049	0.0566379395854604	0.169913818756381	0.213307944885797	0.319961917328695	0.640355507848752	0.640355507848752
Eif3g	ENSMUSG00000070319	0.0117179415987428	0.0351538247962283	0.0436072256433734	0.0654108384650601	0.578396848531894	0.578396848531894

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Aminoacyl-tRNA biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Farsa	ENSMUSG00000003808	0.00481536616919078	0.0144460985075723	0.0230207752632622	0.0345311628948933	0.25141795904251	0.25141795904251
Nars2	ENSMUSG00000018995	0.0073134885581712	0.0219404656745136	0.925444427431699	0.925444427431699	0.454600801949285	0.681901202923927
Qrsl1	ENSMUSG00000019863	0.853801250889739	0.853801250889739	0.577259514257969	0.853801250889739	0.119631084167591	0.358893252502774
Wars	ENSMUSG00000021266	0.0441715176243983	0.132514552873195	0.853801250889739	0.853801250889739	0.780851835278817	0.853801250889739
Yars2	ENSMUSG00000022792	0.144820068500793	0.144820068500793	0.0116356061791785	0.0349068185375355	0.112265881554681	0.144820068500793
Lars	ENSMUSG00000024493	0.346527959006435	0.346527959006435	0.0236697127745139	0.0710091383235417	0.255530331334266	0.346527959006435
Iars2	ENSMUSG00000026618	0.513665062682276	0.867170057724026	1	1	0.578113371816017	0.867170057724026
Aars	ENSMUSG00000031960	0.17924968721805	0.450143880930327	0.853372965654504	0.853372965654504	0.300095920620218	0.450143880930327
Pars2	ENSMUSG00000043572	0.211110344399808	0.633331033199425	0.782117202022501	0.782117202022501	0.641867098978197	0.782117202022501
Sars2	ENSMUSG00000070699	0.0168921052924602	0.0506763158773805	0.0763619660358787	0.114542949053818	0.214764523938594	0.214764523938594

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Cushing syndrome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Atf6b	ENSMUSG00000015461	0.0171027900598199	0.0513083701794598	0.248769231421035	0.373153847131552	0.642366752097095	0.642366752097095
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Gnaq	ENSMUSG00000024639	0.397384062266614	0.398829756175299	0.398829756175299	0.398829756175299	0.300095920620218	0.398829756175299
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Gnas	ENSMUSG00000027523	0.148115998140416	0.222173997210623	0.0579478375430677	0.173843512629203	0.851954599472143	0.851954599472143
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Cdkn2c	ENSMUSG00000028551	0.0164739112492867	0.0360931285010865	0.024062085667391	0.0360931285010865	0.148772260628989	0.148772260628989
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Star	ENSMUSG00000031574	0.0756145297453646	0.113421794618047	0.252545530864481	0.252545530864481	0.0553321944628787	0.113421794618047
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Kcnk2	ENSMUSG00000037624	0.120241108790035	0.360723326370105	0.640608766263372	0.640608766263372	0.344663224299303	0.516994836448954
Armc5	ENSMUSG00000042178	0.0588232673880149	0.176469802164045	0.252545530864481	0.294820734456232	0.294820734456232	0.294820734456232
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Kcnk3	ENSMUSG00000049265	0.45596561163947	0.45596561163947	0.0331400397096515	0.0994201191289544	0.21549027811633	0.323235417174495
Orai1	ENSMUSG00000049686	0.513665062682275	0.711240436189781	0.345037391052887	0.711240436189781	0.711240436189781	0.711240436189781
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404
Cdkn2b	ENSMUSG00000073802	0.0158546704257246	0.0475640112771739	0.144820068500793	0.216214347033995	0.216214347033995	0.216214347033995

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Mitophagy - animal

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tfe3	ENSMUSG00000000134	0.180293335960318	0.540880007880955	0.453570536021945	0.680355804032917	0.926550375688041	0.926550375688041
Sqstm1	ENSMUSG00000015837	0.17610058307789	0.52830174923367	0.513665062682276	0.711650020253571	0.711650020253571	0.711650020253571
Tbc1d15	ENSMUSG00000020130	0.635703516568382	0.635703516568382	0.0321889748775514	0.0965669246326542	0.208897379073412	0.313346068610118
Tfeb	ENSMUSG00000023990	0.0075577836449293	0.0226733509347879	0.0592616003460512	0.0888924005190769	0.92622377157404	0.92622377157404
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Usp30	ENSMUSG00000029592	0.0449262652924809	0.134778795877443	0.178901132102684	0.268351698154027	0.454600801949285	0.454600801949285
Atg9a	ENSMUSG00000033124	0.0579478375430677	0.173843512629203	0.211844580334808	0.317766870502212	1	1
Atg5	ENSMUSG00000038160	0.452880492349546	0.779888212132595	0.640861491578951	0.779888212132595	0.779888212132595	0.779888212132595
Atf4	ENSMUSG00000042406	0.117185073436597	0.175777610154895	0.0434194723707708	0.130258417112313	0.56903312490074	0.56903312490074
Mapk10	ENSMUSG00000046709	0.577259514257969	0.642864324224729	0.45596561163947	0.642864324224729	0.642864324224729	0.642864324224729
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904

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Hepatocellular carcinoma

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Txnrd3	ENSMUSG00000000811	0.00270924971713392	0.00812774915140177	0.0947558980989549	0.0947558980989549	0.0756145297453649	0.0947558980989549
Smarcb1	ENSMUSG00000000902	0.0936419271039906	0.140462890655986	0.0579478375430677	0.140462890655986	1	1
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
E2f3	ENSMUSG00000016477	0.578113371816017	0.578113371816017	0.0583853430099097	0.114542949053818	0.0763619660358786	0.114542949053818
E2f2	ENSMUSG00000018983	0.0741204440774082	0.222361332232225	0.853801250889739	0.853801250889739	0.399548817627028	0.599323226440542
Txnrd1	ENSMUSG00000020250	0.456305241393103	0.576112968612194	0.297848640636703	0.576112968612194	0.576112968612194	0.576112968612194
Cdkn1a	ENSMUSG00000023067	0.346899083932133	0.453225835454266	0.400265374208515	0.453225835454266	0.453225835454266	0.453225835454266
Phf10	ENSMUSG00000023883	0.777255087907932	0.777255087907932	0.454600801949285	0.681901202923927	0.00416720419511757	0.0125016125853527
Lrp5	ENSMUSG00000024913	0.509144723230069	0.763717084845103	0.21549027811633	0.64647083434899	0.776919261684345	0.776919261684345
Gsto1	ENSMUSG00000025068	0.926003599371282	0.926003599371282	0.072378961026407	0.217136883079221	0.578113371816017	0.867170057724026
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
E2f1	ENSMUSG00000027490	0.144489143676808	0.433467431030424	0.711445446052875	0.711445446052875	0.643112334413352	0.711445446052875
Wnt2b	ENSMUSG00000027840	0.852504981253341	0.852504981253341	0.0763619660358788	0.229085898107636	0.454600801949285	0.681901202923927
Nras	ENSMUSG00000027852	0.575824878403157	0.575824878403157	0.25141795904251	0.377126938563765	0.0964252305385473	0.289275691615642
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Wnt5b	ENSMUSG00000030170	0.148772260628989	0.223158390943484	0.072627622984314	0.217882868952942	0.926550375688041	0.926550375688041
Dpf1	ENSMUSG00000030584	0.000333936947699977	0.00100181084309993	0.781170242226513	0.781170242226513	0.148115998140415	0.222173997210623
Gsta4	ENSMUSG00000032348	0.0331400397096514	0.0994201191289543	0.636229315311352	0.636229315311352	0.214764523938594	0.322146785907891
Smarcc1	ENSMUSG00000032481	0.255530331334266	0.640355507848752	0.453225835454266	0.640355507848752	0.640355507848752	0.640355507848752
Gadd45a	ENSMUSG00000036390	0.926550375688041	0.926550375688041	0.119936171404379	0.319961917328694	0.213307944885796	0.319961917328694
Wnt4	ENSMUSG00000036856	0.0447373296833731	0.0671059945250596	0.0321889748775513	0.0671059945250596	0.0748673451455298	0.0748673451455298
Tgfb2	ENSMUSG00000039239	0.925613508363027	0.925613508363027	0.177153312234059	0.531459936702178	0.513346277289108	0.770019415933663
Fzd1	ENSMUSG00000044674	0.348008842235184	0.348008842235184	0.0167871584516597	0.0503614753549792	0.215852522998047	0.323778784497071
Fzd2	ENSMUSG00000050288	0.120545895661627	0.180818843492441	0.0328221470541517	0.098466441162455	0.252545530864481	0.252545530864481
Trp53	ENSMUSG00000059552	0.0115535350288052	0.0346606050864156	0.058823267388015	0.0882349010820225	0.77858338846904	0.77858338846904
Ccnd1	ENSMUSG00000070348	0.0007950941817707	0.0023852825453121	0.641867098978198	0.92622377157404	0.92622377157404	0.92622377157404

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Collagen degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mmp14	ENSMUSG00000000957	0.0434194723707708	0.130258417112313	0.119631084167592	0.179446626251387	0.853694531487825	0.853694531487825
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Col18a1	ENSMUSG00000001435	0.399548817627028	0.599323226440542	0.0763619660358786	0.229085898107636	0.711854160331342	0.711854160331342
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Ctsb	ENSMUSG00000021939	0.148772260628989	0.44337167859054	0.29558111906036	0.44337167859054	0.453225835454266	0.453225835454266
Col11a2	ENSMUSG00000024330	0.0166824765447319	0.0500474296341957	0.92622377157404	0.92622377157404	0.0756145297453648	0.113421794618047
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Col15a1	ENSMUSG00000028339	0.058823267388015	0.0882349010820225	0.00743512899358789	0.0223053869807637	0.85117361048289	0.85117361048289
Furin	ENSMUSG00000030530	0.148772260628989	0.446316781886967	0.577829325134931	0.853480389728993	0.853480389728993	0.853480389728993
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Mmp2	ENSMUSG00000031740	0.179945789077372	0.269918683616058	0.0076814493263989	0.0230443479791967	0.78180291566155	0.78180291566155
Mmp15	ENSMUSG00000031790	0.513665062682276	0.770497594023414	0.023669712774514	0.0710091383235419	1	1
Mmp13	ENSMUSG00000050578	0.177153312234059	0.531459936702178	0.398108175780842	0.597162263671263	0.853801250889739	0.853801250889739
Col13a1	ENSMUSG00000058806	0.711854160331342	0.711854160331342	0.0451153644990944	0.135346093497283	0.711854160331342	0.711854160331342

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Collagen biosynthesis and modifying enzymes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Col18a1	ENSMUSG00000001435	0.399548817627028	0.599323226440542	0.0763619660358786	0.229085898107636	0.711854160331342	0.711854160331342
Plod3	ENSMUSG00000004846	0.0441715176243983	0.132514552873195	0.254787123615605	0.382180685423408	0.454600801949285	0.454600801949285
Plod1	ENSMUSG00000019055	1	1	0.0432318933800775	0.129695680140233	0.926550375688041	1
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Col14a1	ENSMUSG00000022371	0.343537039781257	0.515305559671886	0.024062085667391	0.072186257002173	0.711650020253571	0.711650020253571
Col11a2	ENSMUSG00000024330	0.0166824765447319	0.0500474296341957	0.92622377157404	0.92622377157404	0.0756145297453648	0.113421794618047
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Col15a1	ENSMUSG00000028339	0.058823267388015	0.0882349010820225	0.00743512899358789	0.0223053869807637	0.85117361048289	0.85117361048289
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Col16a1	ENSMUSG00000040690	0.297848640636702	0.446772960955053	0.0449262652924809	0.134778795877443	0.45596561163947	0.45596561163947
Adamts3	ENSMUSG00000043635	0.0964252305385472	0.289275691615642	0.213307944885796	0.319961917328694	0.398829756175299	0.398829756175299
Col13a1	ENSMUSG00000058806	0.711854160331342	0.711854160331342	0.0451153644990944	0.135346093497283	0.711854160331342	0.711854160331342
Adamts14	ENSMUSG00000059901	0.348377561241889	0.683438032073173	0.455625354715449	0.683438032073173	0.711034989117171	0.711034989117171
Col23a1	ENSMUSG00000063564	0.255901190956604	0.383851786434906	0.0964252305385474	0.289275691615642	1	1
Serpinh1	ENSMUSG00000070436	0.643853282854191	0.926658283600152	0.0443599545252853	0.133079863575856	0.926658283600152	0.926658283600152

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Signaling by VEGF

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Jup	ENSMUSG00000001552	0.118714930081337	0.35614479024401	0.509798138101151	0.764697207151727	0.852065168704833	0.852065168704833
Akt1	ENSMUSG00000001729	0.398108175780842	0.684457862089655	0.456305241393103	0.684457862089655	0.78180291566155	0.78180291566155
Hspb1	ENSMUSG00000004951	0.508488713161374	0.508488713161374	0.0331400397096515	0.0994201191289544	0.120850531362929	0.181275797044394
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Cyba	ENSMUSG00000006519	0.00033393694769998	0.00100181084309994	0.297472133192261	0.446208199788392	0.642117186565222	0.642117186565222
Mapkapk2	ENSMUSG00000016528	0.0116356061791785	0.0253381579386902	0.0168921052924602	0.0253381579386902	0.707899741868332	0.707899741868332
Wasf1	ENSMUSG00000019831	0.926333123228344	0.926333123228344	0.400265374208515	0.600398061312773	0.0969812105731563	0.290943631719469
Flt4	ENSMUSG00000020357	0.21549027811633	0.323235417174495	0.21549027811633	0.323235417174495	0.573498913947369	0.573498913947369
Ptk2	ENSMUSG00000022607	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296722	0.642366752097095	0.642366752097095
Vegfb	ENSMUSG00000024962	0.513665062682276	0.513665062682276	0.255530331334266	0.383295497001398	0.0746183450292886	0.223855035087866
Baiap2	ENSMUSG00000025372	0.0168921052924601	0.0506763158773803	1	1	0.447265995733381	0.670898993600072
Hras	ENSMUSG00000025499	0.0331400397096514	0.0497100595644772	0.00731348855817121	0.0219404656745136	0.21549027811633	0.21549027811633
Nrp1	ENSMUSG00000025810	0.0443599545252852	0.0882349010820223	0.0588232673880149	0.0882349010820223	0.7802108304765	0.7802108304765
Them4	ENSMUSG00000028145	0.119631084167592	0.358893252502775	0.92622377157404	0.92622377157404	0.513665062682276	0.770497594023414
Nos3	ENSMUSG00000028978	0.148772260628989	0.148772260628989	0.0753654386865989	0.113048158029898	0.0334587898203824	0.100376369461147
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Figf	ENSMUSG00000031380	0.338207314205573	0.338207314205573	0.249149148271417	0.338207314205573	0.0329809855655598	0.0989429566966793
Vegfc	ENSMUSG00000031520	0.255901190956604	0.255901190956604	0.0964252305385471	0.145471815859735	0.0969812105731563	0.145471815859735
Cdh5	ENSMUSG00000031871	0.514934023620345	0.710208797518812	0.254414773803597	0.710208797518812	0.710208797518812	0.710208797518812
Nck1	ENSMUSG00000032475	0.0434194723707708	0.130258417112313	0.398829756175299	0.598244634262948	0.926658283600152	0.926658283600152
Ctnnd1	ENSMUSG00000034101	0.21549027811633	0.64647083434899	0.777922216623952	0.85117361048289	0.85117361048289	0.85117361048289
Prr5	ENSMUSG00000036106	0.177853449259986	0.382180685423407	0.254787123615605	0.382180685423407	0.400265374208515	0.400265374208515
Shb	ENSMUSG00000044813	0.341647690705446	0.450444934184773	0.450444934184773	0.450444934184773	0.178901132102684	0.450444934184773

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Collagen formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Col18a1	ENSMUSG00000001435	0.399548817627028	0.599323226440542	0.0763619660358786	0.229085898107636	0.711854160331342	0.711854160331342
Plod3	ENSMUSG00000004846	0.0441715176243983	0.132514552873195	0.254787123615605	0.382180685423408	0.454600801949285	0.454600801949285
Mmp9	ENSMUSG00000017737	0.300095920620218	0.450143880930327	0.00442026986621115	0.0132608095986335	0.711034989117171	0.711034989117171
Plod1	ENSMUSG00000019055	1	1	0.0432318933800775	0.129695680140233	0.926550375688041	1
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Ctsb	ENSMUSG00000021939	0.148772260628989	0.44337167859054	0.29558111906036	0.44337167859054	0.453225835454266	0.453225835454266
Col14a1	ENSMUSG00000022371	0.343537039781257	0.515305559671886	0.024062085667391	0.072186257002173	0.711650020253571	0.711650020253571
Col11a2	ENSMUSG00000024330	0.0166824765447319	0.0500474296341957	0.92622377157404	0.92622377157404	0.0756145297453648	0.113421794618047
Loxl4	ENSMUSG00000025185	0.45596561163947	0.683948417459205	0.397746436553874	0.683948417459205	0.85326530496423	0.85326530496423
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Col15a1	ENSMUSG00000028339	0.058823267388015	0.0882349010820225	0.00743512899358789	0.0223053869807637	0.85117361048289	0.85117361048289
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Col16a1	ENSMUSG00000040690	0.297848640636702	0.446772960955053	0.0449262652924809	0.134778795877443	0.45596561163947	0.45596561163947
Adamts3	ENSMUSG00000043635	0.0964252305385472	0.289275691615642	0.213307944885796	0.319961917328694	0.398829756175299	0.398829756175299
Mmp13	ENSMUSG00000050578	0.177153312234059	0.531459936702178	0.398108175780842	0.597162263671263	0.853801250889739	0.853801250889739
Col13a1	ENSMUSG00000058806	0.711854160331342	0.711854160331342	0.0451153644990944	0.135346093497283	0.711854160331342	0.711854160331342
Adamts14	ENSMUSG00000059901	0.348377561241889	0.683438032073173	0.455625354715449	0.683438032073173	0.711034989117171	0.711034989117171
Col23a1	ENSMUSG00000063564	0.255901190956604	0.383851786434906	0.0964252305385474	0.289275691615642	1	1
Serpinh1	ENSMUSG00000070436	0.643853282854191	0.926658283600152	0.0443599545252853	0.133079863575856	0.926658283600152	0.926658283600152

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Neuronal System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gnai3	ENSMUSG00000000001	0.144157978128026	0.216236967192039	0.0106683870753909	0.0320051612261727	0.5155648232968	0.5155648232968
Dlgap1	ENSMUSG00000003279	0.0219958379984644	0.0659875139953931	0.709793037667153	0.709793037667153	0.574083973533718	0.709793037667153
Rps6ka1	ENSMUSG00000003644	0.25141795904251	0.521459286037555	0.347639524025037	0.521459286037555	1	1
Prkaca	ENSMUSG00000005469	0.255530331334266	0.383295497001398	0.121155015244363	0.363465045733089	0.780851835278818	0.780851835278818
Syn2	ENSMUSG00000009394	0.215127611919161	0.215127611919161	0.0590423834359609	0.177127150307883	0.17855224077719	0.215127611919161
Kcnq1	ENSMUSG00000009545	0.254414773803597	0.381622160705395	0.0743693776059065	0.223108132817719	0.781170242226513	0.781170242226513
Hcn2	ENSMUSG00000020331	0.640861491578951	0.640861491578951	0.0592616003460512	0.177784801038154	0.573498913947369	0.640861491578951
Dbnl	ENSMUSG00000020476	0.0321889748775513	0.096566924632654	0.5155648232968	0.7733472349452	0.782117202022501	0.782117202022501
Prkar1a	ENSMUSG00000020612	0.509798138101151	0.764697207151727	0.0753654386865988	0.226096316059796	0.852940894477647	0.852940894477647
Cacnb1	ENSMUSG00000020882	0.119631084167592	0.179446626251388	0.0964252305385473	0.179446626251388	0.926550375688041	0.926550375688041
Gng4	ENSMUSG00000021303	0.782117202022501	0.782117202022501	0.0763619660358786	0.229085898107636	0.511097249598474	0.766645874397711
Adcy4	ENSMUSG00000022220	0.0967032506702098	0.145054876005315	0.0967032506702098	0.145054876005315	0.853694531487825	0.853694531487825
Shank3	ENSMUSG00000022623	0.926604389137101	0.926604389137101	0.174692232033629	0.524076696100887	0.781645261743309	0.926604389137101
Adcy5	ENSMUSG00000022840	0.643359829732651	0.643359829732651	0.00755778364492931	0.0226733509347879	0.174692232033629	0.262038348050444
Maoa	ENSMUSG00000025037	0.513026869856283	0.638824656785692	0.637274134311157	0.638824656785692	0.638824656785692	0.638824656785692
Prkar1b	ENSMUSG00000025855	0.642615797383338	0.642615797383338	0.0235394205027691	0.0706182615083072	0.120545895661628	0.180818843492441
Ppfia4	ENSMUSG00000026458	0.000394209637342663	0.00118262891202799	0.641867098978198	0.641867098978198	0.456305241393103	0.641867098978198
Stxbp1	ENSMUSG00000026797	0.511742979522636	0.767614469283954	0.148115998140416	0.444347994421247	0.852175490580835	0.852175490580835
Grin1	ENSMUSG00000026959	0.21549027811633	0.323235417174495	0.0969812105731562	0.290943631719469	0.400265374208515	0.400265374208515
Chrna1	ENSMUSG00000027107	0.0751163767602348	0.225349130280704	0.576973746230334	0.710622777116399	0.710622777116399	0.710622777116399
Gabra4	ENSMUSG00000029211	0.0902955323751899	0.135443298562785	0.241062360270009	0.241062360270009	0.0902955323751901	0.135443298562785
Aldh2	ENSMUSG00000029455	0.300095920620218	0.450143880930327	0.11810342389482	0.354310271684459	0.92380865295296	0.92380865295296
Lrfn1	ENSMUSG00000030600	0.17855224077719	0.267828361165786	0.120545895661628	0.267828361165786	0.515249728559994	0.515249728559994
Gabra3	ENSMUSG00000031343	0.0451153644990944	0.0676730467486416	0.0116356061791785	0.0349068185375356	0.400265374208515	0.400265374208515
Rab3a	ENSMUSG00000031840	0.712057867818062	0.712057867818062	0.0315593554855452	0.0946780664566356	0.711034989117171	0.712057867818062
Panx1	ENSMUSG00000031934	0.299349060054895	0.449023590082343	0.711034989117171	0.711034989117171	0.295581119060361	0.449023590082343
Grik4	ENSMUSG00000032017	0.216214347033995	0.648643041101984	0.853480389728993	0.853480389728993	0.514300775319626	0.771451162979439
Kcnj5	ENSMUSG00000032034	0.926604389137101	0.926604389137101	0.0332993082165205	0.0998979246495616	0.643606811957488	0.926604389137101
Slitrk5	ENSMUSG00000033214	0.643112334413352	0.853049270252403	0.853049270252403	0.853049270252403	0.0329809855655598	0.0989429566966793
Nsf	ENSMUSG00000034187	0.0592616003460512	0.177784801038154	0.780851835278818	0.780851835278818	0.295581119060361	0.443371678590541
Chrnb4	ENSMUSG00000035200	0.0969812105731561	0.290943631719468	0.642366752097095	0.642366752097095	0.638824656785692	0.642366752097095
Aldh5a1	ENSMUSG00000035936	0.400265374208515	0.711034989117171	0.511742979522636	0.711034989117171	0.711034989117171	0.711034989117171
Lrfn3	ENSMUSG00000036957	0.0334587898203823	0.100376369461147	0.706616781330066	0.706616781330066	0.347639524025037	0.521459286037555
Syn1	ENSMUSG00000037217	1	1	0.347269605097054	0.598784401330551	0.399189600887034	0.598784401330551
Ppfia1	ENSMUSG00000037519	0.21549027811633	0.323235417174495	0.214764523938594	0.323235417174495	0.511742979522636	0.511742979522636
Kcnk2	ENSMUSG00000037624	0.120241108790035	0.360723326370105	0.640608766263372	0.640608766263372	0.344663224299303	0.516994836448954
Kcnj9	ENSMUSG00000038026	0.255158975839805	0.255158975839805	0.17924968721805	0.255158975839805	0.0328221470541517	0.098466441162455
Kcna6	ENSMUSG00000038077	0.704440461749122	0.704440461749122	0.0232795908282423	0.0349193862423634	0.0109864933352154	0.0329594800056461
Lrfn2	ENSMUSG00000040490	1	1	0.849107182150815	1	0.255879749766208	0.767639249298625
Gls2	ENSMUSG00000044005	0.392243127063687	0.393724994268831	0.148115998140416	0.393724994268831	0.393724994268831	0.393724994268831
Kcna5	ENSMUSG00000045534	0.642366752097095	0.642366752097095	0.255901190956604	0.383851786434906	0.21549027811633	0.383851786434906
Lrrc4b	ENSMUSG00000047085	0.711854160331342	0.711854160331342	0.250285839267991	0.375428758901986	0.211110344399808	0.375428758901986
Kcnk3	ENSMUSG00000049265	0.45596561163947	0.45596561163947	0.0331400397096515	0.0994201191289544	0.21549027811633	0.323235417174495
Kcnn4	ENSMUSG00000054342	0.00276975149305653	0.00415462723958479	0.00253244992826164	0.00415462723958479	0.390750658104794	0.390750658104794
Kcnq3	ENSMUSG00000056258	0.455284468727762	0.770019415933663	0.513346277289108	0.770019415933663	0.92616891281798	0.92616891281798
Tspan7	ENSMUSG00000058254	0.0447373296833729	0.0671059945250594	0.0443599545252853	0.0671059945250594	0.92589277149125	0.92589277149125
Grin2a	ENSMUSG00000059003	0.642366752097095	0.642366752097095	0.642366752097095	0.642366752097095	0.575536202757516	0.642366752097095
Flot2	ENSMUSG00000061981	0.146800541856249	0.440401625568746	0.5155648232968	0.5155648232968	0.513665062682276	0.5155648232968
Gng8	ENSMUSG00000063594	0.925217182211634	0.925217182211634	0.578113371816017	0.867170057724026	0.340887582990546	0.867170057724026
Gng3	ENSMUSG00000071658	0.642366752097095	0.642366752097095	0.253294730253594	0.449023590082343	0.299349060054895	0.449023590082343

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Collagen chain trimerization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col6a1	ENSMUSG00000001119	0.711650020253571	0.853907737111068	0.0164739112492867	0.0494217337478602	0.853907737111068	0.853907737111068
Col18a1	ENSMUSG00000001435	0.399548817627028	0.599323226440542	0.0763619660358786	0.229085898107636	0.711854160331342	0.711854160331342
Col6a2	ENSMUSG00000020241	0.398829756175299	0.598244634262948	0.0236697127745139	0.0710091383235417	0.78180291566155	0.78180291566155
Col14a1	ENSMUSG00000022371	0.343537039781257	0.515305559671886	0.024062085667391	0.072186257002173	0.711650020253571	0.711650020253571
Col11a2	ENSMUSG00000024330	0.0166824765447319	0.0500474296341957	0.92622377157404	0.92622377157404	0.0756145297453648	0.113421794618047
Col3a1	ENSMUSG00000026043	0.5155648232968	0.7733472349452	0.00755778364492931	0.0226733509347879	0.782117202022501	0.782117202022501
Col15a1	ENSMUSG00000028339	0.058823267388015	0.0882349010820225	0.00743512899358789	0.0223053869807637	0.85117361048289	0.85117361048289
Col4a1	ENSMUSG00000031502	0.346527959006435	0.514934023620345	0.0334587898203823	0.100376369461147	0.514934023620345	0.514934023620345
Col4a2	ENSMUSG00000031503	0.511742979522636	0.511742979522636	0.0443599545252853	0.133079863575856	0.455625354715449	0.511742979522636
Col16a1	ENSMUSG00000040690	0.297848640636702	0.446772960955053	0.0449262652924809	0.134778795877443	0.45596561163947	0.45596561163947
Col13a1	ENSMUSG00000058806	0.711854160331342	0.711854160331342	0.0451153644990944	0.135346093497283	0.711854160331342	0.711854160331342
Col23a1	ENSMUSG00000063564	0.255901190956604	0.383851786434906	0.0964252305385474	0.289275691615642	1	1

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Cell-cell junction organization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Jup	ENSMUSG00000001552	0.118714930081337	0.35614479024401	0.509798138101151	0.764697207151727	0.852065168704833	0.852065168704833
Cadm3	ENSMUSG00000005338	0.643606811957488	0.643606811957488	0.514617706526787	0.643606811957488	0.255158975839805	0.643606811957488
Cdh10	ENSMUSG00000022321	0.926387617028817	1	1	1	0.452880492349545	1
Cdh2	ENSMUSG00000024304	0.576973746230334	0.781170242226513	0.0419238354397911	0.125771506319373	0.781170242226513	0.781170242226513
Pard3	ENSMUSG00000025812	0.781170242226513	0.781170242226513	0.711034989117171	0.781170242226513	0.513026869856283	0.781170242226513
Actb	ENSMUSG00000029580	0.0241933715424143	0.0725801146272428	0.711854160331342	0.78180291566155	0.78180291566155	0.78180291566155
Cdh13	ENSMUSG00000031841	0.853480389728993	0.853480389728993	0.120545895661628	0.361637686984883	0.78180291566155	0.853480389728993
Cdh5	ENSMUSG00000031871	0.514934023620345	0.710208797518812	0.254414773803597	0.710208797518812	0.710208797518812	0.710208797518812
Cadm1	ENSMUSG00000032076	0.853694531487825	0.853694531487825	0.120545895661628	0.361637686984883	0.576973746230334	0.853694531487825
Ctnnd1	ENSMUSG00000034101	0.21549027811633	0.64647083434899	0.777922216623952	0.85117361048289	0.85117361048289	0.85117361048289
Pard6g	ENSMUSG00000056214	0.112265881554681	0.168398822332022	0.00130806497567845	0.00392419492703534	0.643853282854191	0.643853282854191
Pvrl2	ENSMUSG00000062300	0.0116356061791785	0.0349068185375354	0.453225835454266	0.5155648232968	0.5155648232968	0.5155648232968

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blue2

ECM-receptor interaction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itga5	ENSMUSG00000000555	0.0947558980989553	0.115651627788147	0.0325051220296005	0.0975153660888015	0.115651627788147	0.115651627788147
Col1a1	ENSMUSG00000001506	0.211110344399808	0.316665516599712	0.0241933715424143	0.0725801146272428	0.575824878403157	0.575824878403157
Lamc1	ENSMUSG00000026478	0.0969812105731562	0.144157978128026	0.00481536616919075	0.0144460985075723	0.144157978128026	0.144157978128026
Col1a2	ENSMUSG00000029661	0.25141795904251	0.377126938563765	0.00289311433957183	0.0086793430187155	0.711650020253571	0.711650020253571
Sv2a	ENSMUSG00000038486	0.255901190956604	0.255901190956604	0.144157978128026	0.255901190956604	0.25141795904251	0.255901190956604
Reln	ENSMUSG00000042453	0.926441990075769	0.926441990075769	0.00481536616919078	0.0144460985075723	0.148772260628989	0.223158390943484
Col6a3	ENSMUSG00000048126	0.0969812105731562	0.145471815859734	0.000679874196828787	0.00203962259048636	0.634645058916812	0.634645058916812

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Proteoglycans in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Wnt3	ENSMUSG00000000125	0.575536202757516	0.863304304136274	0.507830090867449	0.863304304136274	0.9255572759333	0.9255572759333
Wnt9a	ENSMUSG00000000126	0.214037080764326	0.321055621146488	0.0575107614292585	0.172532284287776	0.344663224299303	0.344663224299303
Itga5	ENSMUSG00000000555	0.0947558980989553	0.115651627788147	0.0325051220296005	0.0975153660888015	0.115651627788147	0.115651627788147
Fasl	ENSMUSG00000000817	0.0746183450292886	0.111927517543933	0.00481536616919075	0.0144460985075723	0.297095062262363	0.297095062262363
Col1a1	ENSMUSG00000001506	0.211110344399808	0.316665516599712	0.0241933715424143	0.0725801146272428	0.575824878403157	0.575824878403157
Cdc42	ENSMUSG00000006699	0.640861491578951	0.640861491578951	0.113190884633071	0.339572653899213	0.637274134311157	0.640861491578951
Col1a2	ENSMUSG00000029661	0.25141795904251	0.377126938563765	0.00289311433957183	0.0086793430187155	0.711650020253571	0.711650020253571
Flna	ENSMUSG00000031328	0.346899083932133	0.346899083932133	0.00743512899358789	0.0223053869807637	0.211844580334808	0.317766870502212
Hspb2	ENSMUSG00000038086	0.851732715229127	0.851732715229127	0.12085053136293	0.181275797044394	0.0763619660358787	0.181275797044394
Fzd9	ENSMUSG00000049551	0.576973746230334	0.640355507848752	0.00153425095635555	0.00460275286906664	0.640355507848752	0.640355507848752
Gpc3	ENSMUSG00000055653	0.157372722062346	0.23605908309352	0.00768144932639892	0.0230443479791968	0.575824878403157	0.575824878403157

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Metabolic pathways

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Th	ENSMUSG00000000214	0.298974794311434	0.448462191467151	0.0113089139751576	0.0339267419254727	0.45596561163947	0.45596561163947
Ckb	ENSMUSG00000001270	0.643359829732651	0.92622377157404	0.000795094181770697	0.00238528254531209	0.92622377157404	0.92622377157404
Acp5	ENSMUSG00000001348	0.0315593554855452	0.0946780664566357	0.0733738589968007	0.110060788495201	0.924405146515181	0.924405146515181
Tcirg1	ENSMUSG00000001750	0.044737329683373	0.134211989050119	0.254787123615605	0.382180685423408	0.442211413534162	0.442211413534162
Naglu	ENSMUSG00000001751	0.0575107614292585	0.0862661421438878	0.0451153644990945	0.0862661421438878	0.853801250889739	0.853801250889739
Coasy	ENSMUSG00000001755	0.254787123615605	0.382180685423408	0.0579478375430678	0.173843512629203	0.852940894477647	0.852940894477647
Itpkc	ENSMUSG00000003752	0.0703913497478892	0.211174049243667	0.641867098978198	0.642864324224729	0.642864324224729	0.642864324224729
Acaa1b	ENSMUSG00000010651	0.708745765211584	0.708745765211584	0.0880615565264046	0.264184669579214	0.702439833942814	0.708745765211584
Odc1	ENSMUSG00000011179	0.0421101560083838	0.126330468025151	0.853049270252403	1	1	1
Ehmt2	ENSMUSG00000013787	0.0566379395854603	0.110060788495201	0.853694531487825	0.853694531487825	0.0733738589968007	0.110060788495201
Prune	ENSMUSG00000015711	0.0592616003460512	0.177784801038154	0.294820734456232	0.442231101684348	0.643853282854191	0.643853282854191
Acot8	ENSMUSG00000017307	0.179249687218049	0.268874530827074	0.454600801949285	0.454600801949285	0.0947558980989551	0.268874530827074
Afmid	ENSMUSG00000017718	0.336273664439462	0.778911768167544	0.778911768167544	0.778911768167544	0.640861491578951	0.778911768167544
Alox15	ENSMUSG00000018924	0.706831781264721	0.706831781264721	0.0886202385494147	0.221188136557642	0.147458757705094	0.221188136557642
Mgat1	ENSMUSG00000020346	0.00442026986621115	0.0132608095986335	0.0232795908282423	0.0349193862423634	0.148772260628989	0.148772260628989
Ltc4s	ENSMUSG00000020377	0.710001140920767	0.710001140920767	0.00660511570760555	0.0198153471228166	0.205174703261494	0.307762054892242
Galnt10	ENSMUSG00000020520	0.120545895661627	0.180818843492441	0.059042383435961	0.177127150307883	1	1
Plcd3	ENSMUSG00000020937	0.348008842235184	0.348008842235184	0.11993617140438	0.317766870502212	0.211844580334808	0.317766870502212
L2hgdh	ENSMUSG00000020988	0.0964252305385472	0.144637845807821	0.0328221470541517	0.098466441162455	0.179249687218049	0.179249687218049
9030617O03Rik	ENSMUSG00000021185	0.924872384323464	0.924872384323464	0.168646652367079	0.505939957101236	0.43283647035887	0.649254705538306
Acot2	ENSMUSG00000021226	0.215852522998048	0.295201212209107	0.0108268982515582	0.0324806947546745	0.295201212209107	0.295201212209107
Ggps1	ENSMUSG00000021302	0.255901190956604	0.383851786434906	0.0426702157436794	0.128010647231038	0.852940894477647	0.852940894477647
B4galt7	ENSMUSG00000021504	0.0958690133561599	0.14380352003424	0.0449262652924809	0.134778795877443	0.214764523938594	0.214764523938594
Ogdhl	ENSMUSG00000021913	0.000143939694472871	0.000431819083418612	0.00892508641180901	0.0133876296177135	0.298599969973533	0.298599969973533
Extl3	ENSMUSG00000021978	0.0240620856673909	0.0721862570021727	0.0964252305385472	0.144637845807821	0.643853282854191	0.643853282854191
Adsl	ENSMUSG00000022407	0.146800541856249	0.146800541856249	0.117185073436597	0.146800541856249	0.0221230395928304	0.0663691187784912
Cyc1	ENSMUSG00000022551	0.0334587898203823	0.0501881847305734	0.000315345965549257	0.00094603789664777	1	1
Naprt1	ENSMUSG00000022574	0.0334587898203823	0.0501881847305735	0.00695468356472022	0.0208640506941607	0.852832278580641	0.852832278580641
Csad	ENSMUSG00000023044	0.0241933715424143	0.0362900573136214	0.000844544805216502	0.00253363441564951	0.711240436189781	0.711240436189781
Rfk	ENSMUSG00000024712	1	1	0.0451153644990945	0.135346093497283	0.348008842235184	0.522013263352777
Pcx	ENSMUSG00000024892	0.120850531362929	0.181275797044394	0.0158546704257247	0.047564011277174	0.852940894477647	0.852940894477647
Pip4k2c	ENSMUSG00000025417	0.0325051220296005	0.0975153660888015	0.120850531362929	0.181275797044394	0.641867098978198	0.641867098978198
Nnt	ENSMUSG00000025453	0.710001140920767	0.711240436189781	0.00161470887631957	0.00484412662895871	0.711240436189781	0.711240436189781
Sirt3	ENSMUSG00000025486	0.180293335960318	0.180293335960318	0.00743512899358791	0.0223053869807637	0.0312459040565944	0.0468688560848915
Ptdss2	ENSMUSG00000025495	0.399548817627028	0.399548817627028	0.0746183450292888	0.223855035087866	0.345410946355104	0.399548817627028
Asl	ENSMUSG00000025533	0.0334587898203823	0.100376369461147	0.78180291566155	0.78180291566155	0.781170242226513	0.78180291566155
Prps2	ENSMUSG00000025742	0.0158546704257246	0.0475640112771738	0.643359829732651	0.643359829732651	0.11595859961889	0.173937899428335
Hadha	ENSMUSG00000025745	0.398829756175298	0.398829756175298	0.256271555563966	0.384407333345949	0.254414773803597	0.384407333345949
Pgm2	ENSMUSG00000025791	0.78180291566155	0.78180291566155	0.00270924971713393	0.00812774915140178	0.45596561163947	0.683948417459205
Rdh10	ENSMUSG00000025921	0.853372965654504	1	0.0741204440774082	0.222361332232225	1	1
Cps1	ENSMUSG00000025991	0.576973746230334	0.576973746230334	0.11810342389482	0.219212029823693	0.146141353215796	0.219212029823693
Cyp27a1	ENSMUSG00000026170	0.853694531487825	0.926550375688041	0.344663224299303	0.926550375688041	0.926550375688041	0.926550375688041
Ndufa10	ENSMUSG00000026260	0.119631084167592	0.119631084167592	0.00481536616919077	0.0144460985075723	0.11810342389482	0.119631084167592
Prdx6	ENSMUSG00000026701	0.0325051220296005	0.0888924005190769	0.0592616003460512	0.0888924005190769	0.299349060054895	0.299349060054895
Ptges2	ENSMUSG00000026820	0.398108175780842	0.398108175780842	0.171859370212435	0.257789055318653	0.0964252305385472	0.257789055318653
Ivd	ENSMUSG00000027332	0.148772260628989	0.446194239410717	0.395196379647461	0.446194239410717	0.446194239410717	0.446194239410717
Hdc	ENSMUSG00000027360	0.643359829732651	0.781170242226513	0.781170242226513	0.781170242226513	0.711034989117171	0.781170242226513
Nfs1	ENSMUSG00000027618	0.0969812105731562	0.246861959455465	0.242231702094921	0.246861959455465	0.246861959455465	0.246861959455465
Mccc1	ENSMUSG00000027709	0.642864324224729	0.642864324224729	0.00153425095635555	0.00460275286906664	0.119631084167592	0.179446626251387
Hmgcs2	ENSMUSG00000027875	0.707899741868332	0.707899741868332	0.214037080764326	0.642111242292977	0.643359829732651	0.707899741868332
Pigo	ENSMUSG00000028454	0.0449262652924809	0.119631084167592	0.119631084167592	0.119631084167592	0.119631084167592	0.119631084167592
Car9	ENSMUSG00000028463	0.0588232673880149	0.122027477160835	0.0813516514405565	0.122027477160835	0.703556284613037	0.703556284613037
Hmgcl	ENSMUSG00000028672	0.0449262652924809	0.0673893979387214	0.00768144932639892	0.0230443479791968	0.45596561163947	0.45596561163947
Cmpk1	ENSMUSG00000028719	0.00755778364492929	0.0226733509347879	0.0449262652924809	0.0673893979387214	0.34837756124189	0.34837756124189
Lias	ENSMUSG00000029199	0.177153312234059	0.450143880930327	0.300095920620218	0.450143880930327	0.926658283600152	0.926658283600152
Gnpda2	ENSMUSG00000029209	0.00768144932639892	0.0115221739895984	0.00153425095635555	0.00460275286906665	0.779888212132595	0.779888212132595
Aoc1	ENSMUSG00000029811	0.21549027811633	0.323235417174495	0.0436072256433734	0.13082167693012	0.853907737111068	0.853907737111068
Dgat2	ENSMUSG00000030747	0.0964252305385472	0.289275691615642	0.204424977646738	0.306637466470107	0.342026805366747	0.342026805366747
Ears2	ENSMUSG00000030871	0.0451153644990944	0.0676730467486416	0.0953125666339396	0.0953125666339396	0.0434194723707708	0.0676730467486416
Uqcrc2	ENSMUSG00000030884	0.120850531362929	0.181275797044394	0.0548979200435555	0.164693760130667	0.578113371816017	0.578113371816017
Car7	ENSMUSG00000031883	0.120545895661628	0.361637686984883	0.252545530864481	0.378818296296721	0.710001140920767	0.710001140920767
Acad8	ENSMUSG00000031969	0.0328221470541517	0.098466441162455	0.120850531362929	0.179249687218049	0.179249687218049	0.179249687218049
Sc5d	ENSMUSG00000032018	0.0116356061791785	0.0253381579386902	0.0168921052924602	0.0253381579386902	0.924639851733043	0.924639851733043
Treh	ENSMUSG00000032098	0.631413595275176	0.847921313356738	0.00451575818696109	0.0135472745608833	0.847921313356738	0.847921313356738
Hmbs	ENSMUSG00000032126	0.0432318933800774	0.0648478400701161	0.00743512899358787	0.0223053869807636	0.711854160331342	0.711854160331342
Nmnat3	ENSMUSG00000032456	0.450794830295118	0.450794830295118	0.171859370212435	0.416242791166538	0.277495194111025	0.416242791166538
Pccb	ENSMUSG00000032527	0.00477055016690543	0.00715582525035814	0.00270924971713393	0.00715582525035814	1	1
Nt5m	ENSMUSG00000032615	0.0236697127745139	0.0355045691617708	5.46967066778587e-05	0.000164090120033576	0.0761127945805735	0.0761127945805735
Pdxk	ENSMUSG00000032788	0.509798138101151	0.764697207151727	0.00463747559282086	0.0139124267784626	0.7802108304765	0.7802108304765
Entpd6	ENSMUSG00000033068	0.0110666956860337	0.0166000435290505	0.00743512899358789	0.0166000435290505	0.119631084167592	0.119631084167592
Fuk	ENSMUSG00000033703	0.146141353215796	0.219212029823693	0.0113089139751576	0.0339267419254727	0.514300775319626	0.514300775319626
Spr	ENSMUSG00000033735	0.21549027811633	0.323235417174496	0.00264953297731414	0.00794859893194243	1	1
Pomt2	ENSMUSG00000034126	0.578396848531894	0.782117202022501	0.180293335960318	0.540880007880954	0.782117202022501	0.782117202022501
Grhpr	ENSMUSG00000035637	0.21549027811633	0.297095062262362	0.00334677714134022	0.0100403314240207	0.297095062262362	0.297095062262362
Csgalnact1	ENSMUSG00000036356	0.852832278580641	0.926333123228344	0.926333123228344	0.926333123228344	0.852940894477647	0.926333123228344
Pomk	ENSMUSG00000037251	0.000366575037992824	0.00109972511397847	0.0217422311863571	0.0326133467795357	0.344663224299303	0.344663224299303
Galnt6	ENSMUSG00000037280	0.0449262652924809	0.134778795877443	0.0964252305385472	0.144637845807821	0.853801250889739	0.853801250889739
Pafah2	ENSMUSG00000037366	0.216214347033994	0.324321520550992	0.113498953177704	0.324321520550992	0.781170242226513	0.781170242226513
Chpf2	ENSMUSG00000038181	0.00159435459956481	0.00478306379869443	0.0964252305385472	0.0964252305385472	0.0947558980989551	0.0964252305385472
Ndst2	ENSMUSG00000039308	0.0158546704257247	0.047564011277174	0.17924968721805	0.268874530827074	0.781170242226513	0.781170242226513
Alg14	ENSMUSG00000039887	0.255901190956604	0.681901202923927	0.454600801949285	0.681901202923927	0.852832278580641	0.852832278580641
Cox15	ENSMUSG00000040018	0.0588232673880149	0.113421794618047	0.451840588205062	0.451840588205062	0.0756145297453648	0.113421794618047
Ccbl2	ENSMUSG00000040213	0.575824878403157	0.575824878403157	0.0950342596054051	0.285102778816215	0.45253450475104	0.575824878403157
Agmat	ENSMUSG00000040706	0.255530331334266	0.383295497001398	0.00660511570760555	0.0198153471228166	0.853372965654504	0.853372965654504
Ak7	ENSMUSG00000041323	0.346899083932133	0.711650020253571	0.711650020253571	0.711650020253571	0.578396848531894	0.711650020253571
Hibch	ENSMUSG00000041426	0.11810342389482	0.354310271684459	0.255530331334266	0.383295497001398	0.643853282854191	0.643853282854191
Mat2b	ENSMUSG00000042032	0.342026805366747	0.342026805366747	0.0919695072173338	0.275908521652001	0.297848640636702	0.342026805366747
Hsd3b7	ENSMUSG00000042289	0.926333123228344	0.926333123228344	0.34837756124189	0.600398061312773	0.400265374208515	0.600398061312773
Flad1	ENSMUSG00000042642	0.0592616003460512	0.114542949053818	0.576973746230334	0.576973746230334	0.0763619660358786	0.114542949053818
Acp1	ENSMUSG00000044573	0.120850531362929	0.362551594088788	0.395928178642446	0.593892267963669	0.925669613555092	0.925669613555092
B3gnt1	ENSMUSG00000047379	0.0171027900598199	0.0256541850897299	0.00153425095635555	0.00460275286906665	1	1
Fut4	ENSMUSG00000049307	0.255901190956603	0.383851786434905	0.0540308994052097	0.162092698215629	0.852832278580641	0.852832278580641
Ppap2c	ENSMUSG00000052151	0.0162664168407233	0.04879925052217	0.148115998140416	0.222173997210623	0.638824656785692	0.638824656785692
Rpia	ENSMUSG00000053604	0.0007950941817707	0.00230137643453332	0.00153425095635555	0.00230137643453332	0.78148726569172	0.78148726569172
Gapdh	ENSMUSG00000057666	0.578113371816017	0.578113371816017	0.0753654386865988	0.113048158029898	0.0115535350288052	0.0346606050864157
Bckdha	ENSMUSG00000060376	0.0162664168407233	0.024399625261085	0.0113089139751576	0.024399625261085	0.577829325134931	0.577829325134931
Impdh2	ENSMUSG00000062867	0.00768144932639896	0.0115221739895984	0.0073134885581712	0.0115221739895984	1	1
Acadm	ENSMUSG00000062908	0.0733738589968006	0.220121576990402	0.397384062266614	0.596076093399921	0.637793186752488	0.637793186752488
Ppcdc	ENSMUSG00000063849	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342	0.175044824745981	0.525134474237942
Mocs1	ENSMUSG00000064120	0.0441715176243983	0.132514552873195	0.708323672944427	0.926333123228344	0.926333123228344	0.926333123228344
mt-Nd1	ENSMUSG00000064341	0.0964252305385472	0.181275797044394	0.120850531362929	0.181275797044394	0.255530331334266	0.255530331334266
mt-Nd2	ENSMUSG00000064345	0.0579478375430677	0.173843512629203	0.578113371816017	0.578113371816017	0.346527959006435	0.519791938509652
mt-Co1	ENSMUSG00000064351	0.0168921052924602	0.0506763158773805	0.0958690133561599	0.14380352003424	0.214037080764326	0.214037080764326
mt-Atp6	ENSMUSG00000064357	0.0583853430099098	0.175156029029729	0.300095920620218	0.300095920620218	0.256271555563966	0.300095920620218
mt-Nd4	ENSMUSG00000064363	0.0328221470541517	0.098466441162455	0.121155015244363	0.181732522866545	0.514934023620345	0.514934023620345
mt-Cytb	ENSMUSG00000064370	0.0331400397096515	0.0994201191289544	0.255901190956604	0.255901190956604	0.216214347033995	0.255901190956604
Ganab	ENSMUSG00000071650	0.0969812105731563	0.145471815859735	0.0583853430099097	0.145471815859735	0.17750354896016	0.17750354896016
Sms	ENSMUSG00000071708	0.51077343128446	0.766160146926689	1	1	0.45253450475104	0.766160146926689
B3gnt6	ENSMUSG00000074004	0.513665062682276	0.770497594023414	0.287873078401389	0.770497594023414	0.851061028660105	0.851061028660105
Mlycd	ENSMUSG00000074064	0.0236697127745139	0.0355045691617709	0.00153425095635555	0.00460275286906665	0.643853282854191	0.643853282854191
Dpm1	ENSMUSG00000078919	0.573205482926791	0.573205482926791	0.0436072256433733	0.13082167693012	0.298599969973533	0.447899954960299

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Valine, leucine and isoleucine degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Acaa1b	ENSMUSG00000010651	0.708745765211584	0.708745765211584	0.0880615565264046	0.264184669579214	0.702439833942814	0.708745765211584
Hadha	ENSMUSG00000025745	0.398829756175298	0.398829756175298	0.256271555563966	0.384407333345949	0.254414773803597	0.384407333345949
Ivd	ENSMUSG00000027332	0.148772260628989	0.446194239410717	0.395196379647461	0.446194239410717	0.446194239410717	0.446194239410717
Mccc1	ENSMUSG00000027709	0.642864324224729	0.642864324224729	0.00153425095635555	0.00460275286906664	0.119631084167592	0.179446626251387
Hmgcs2	ENSMUSG00000027875	0.707899741868332	0.707899741868332	0.214037080764326	0.642111242292977	0.643359829732651	0.707899741868332
Hmgcl	ENSMUSG00000028672	0.0449262652924809	0.0673893979387214	0.00768144932639892	0.0230443479791968	0.45596561163947	0.45596561163947
Acad8	ENSMUSG00000031969	0.0328221470541517	0.098466441162455	0.120850531362929	0.179249687218049	0.179249687218049	0.179249687218049
Pccb	ENSMUSG00000032527	0.00477055016690543	0.00715582525035814	0.00270924971713393	0.00715582525035814	1	1
Hibch	ENSMUSG00000041426	0.11810342389482	0.354310271684459	0.255530331334266	0.383295497001398	0.643853282854191	0.643853282854191
Bckdha	ENSMUSG00000060376	0.0162664168407233	0.024399625261085	0.0113089139751576	0.024399625261085	0.577829325134931	0.577829325134931
Acadm	ENSMUSG00000062908	0.0733738589968006	0.220121576990402	0.397384062266614	0.596076093399921	0.637793186752488	0.637793186752488

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Biosynthesis of cofactors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Coasy	ENSMUSG00000001755	0.254787123615605	0.382180685423408	0.0579478375430678	0.173843512629203	0.852940894477647	0.852940894477647
Afmid	ENSMUSG00000017718	0.336273664439462	0.778911768167544	0.778911768167544	0.778911768167544	0.640861491578951	0.778911768167544
Adsl	ENSMUSG00000022407	0.146800541856249	0.146800541856249	0.117185073436597	0.146800541856249	0.0221230395928304	0.0663691187784912
Naprt1	ENSMUSG00000022574	0.0334587898203823	0.0501881847305735	0.00695468356472022	0.0208640506941607	0.852832278580641	0.852832278580641
Rfk	ENSMUSG00000024712	1	1	0.0451153644990945	0.135346093497283	0.348008842235184	0.522013263352777
Nfs1	ENSMUSG00000027618	0.0969812105731562	0.246861959455465	0.242231702094921	0.246861959455465	0.246861959455465	0.246861959455465
Cmpk1	ENSMUSG00000028719	0.00755778364492929	0.0226733509347879	0.0449262652924809	0.0673893979387214	0.34837756124189	0.34837756124189
Lias	ENSMUSG00000029199	0.177153312234059	0.450143880930327	0.300095920620218	0.450143880930327	0.926658283600152	0.926658283600152
Ears2	ENSMUSG00000030871	0.0451153644990944	0.0676730467486416	0.0953125666339396	0.0953125666339396	0.0434194723707708	0.0676730467486416
Hmbs	ENSMUSG00000032126	0.0432318933800774	0.0648478400701161	0.00743512899358787	0.0223053869807636	0.711854160331342	0.711854160331342
Nmnat3	ENSMUSG00000032456	0.450794830295118	0.450794830295118	0.171859370212435	0.416242791166538	0.277495194111025	0.416242791166538
Pdxk	ENSMUSG00000032788	0.509798138101151	0.764697207151727	0.00463747559282086	0.0139124267784626	0.7802108304765	0.7802108304765
Spr	ENSMUSG00000033735	0.21549027811633	0.323235417174496	0.00264953297731414	0.00794859893194243	1	1
Cox15	ENSMUSG00000040018	0.0588232673880149	0.113421794618047	0.451840588205062	0.451840588205062	0.0756145297453648	0.113421794618047
Ak7	ENSMUSG00000041323	0.346899083932133	0.711650020253571	0.711650020253571	0.711650020253571	0.578396848531894	0.711650020253571
Mat2b	ENSMUSG00000042032	0.342026805366747	0.342026805366747	0.0919695072173338	0.275908521652001	0.297848640636702	0.342026805366747
Flad1	ENSMUSG00000042642	0.0592616003460512	0.114542949053818	0.576973746230334	0.576973746230334	0.0763619660358786	0.114542949053818
Ppcdc	ENSMUSG00000063849	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342	0.175044824745981	0.525134474237942
Mocs1	ENSMUSG00000064120	0.0441715176243983	0.132514552873195	0.708323672944427	0.926333123228344	0.926333123228344	0.926333123228344

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Riboflavin metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Acp5	ENSMUSG00000001348	0.0315593554855452	0.0946780664566357	0.0733738589968007	0.110060788495201	0.924405146515181	0.924405146515181
Rfk	ENSMUSG00000024712	1	1	0.0451153644990945	0.135346093497283	0.348008842235184	0.522013263352777
Flad1	ENSMUSG00000042642	0.0592616003460512	0.114542949053818	0.576973746230334	0.576973746230334	0.0763619660358786	0.114542949053818
Acp1	ENSMUSG00000044573	0.120850531362929	0.362551594088788	0.395928178642446	0.593892267963669	0.925669613555092	0.925669613555092

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Autophagy - other

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppp2ca	ENSMUSG00000020349	0.782117202022501	0.853907737111068	0.711034989117171	0.853907737111068	0.853907737111068	0.853907737111068
Atg10	ENSMUSG00000021619	0.0741204440774082	0.222361332232225	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571
Mlst8	ENSMUSG00000024142	0.0753654386865988	0.226096316059796	0.21549027811633	0.323235417174495	0.513026869856283	0.513026869856283
Atg4b	ENSMUSG00000026280	0.0947558980989551	0.0964252305385472	0.00719286546902974	0.0215785964070892	0.0964252305385472	0.0964252305385472
Atg7	ENSMUSG00000030314	0.0583853430099097	0.175156029029729	0.216214347033995	0.297848640636702	0.297848640636702	0.297848640636702
Pik3r4	ENSMUSG00000032571	0.0575107614292584	0.0862661421438877	0.255901190956604	0.255901190956604	0.0241933715424143	0.072580114627243
Atg12	ENSMUSG00000032905	0.179945789077371	0.539837367232114	0.5155648232968	0.7733472349452	0.926003599371282	0.926003599371282

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burlywood

Focal adhesion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Actn1	ENSMUSG00000015143	0.513665062682276	0.640861491578951	0.451840588205062	0.640861491578951	0.640861491578951	0.640861491578951
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Rac3	ENSMUSG00000018012	0.450794830295118	0.684457862089655	0.456305241393103	0.684457862089655	0.711034989117171	0.711034989117171
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Vcl	ENSMUSG00000021823	0.17924968721805	0.537749061654149	0.78180291566155	0.926658283600152	0.926658283600152	0.926658283600152
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Capn2	ENSMUSG00000026509	0.577829325134931	0.577829325134931	0.454942951775341	0.577829325134931	0.572616808177226	0.577829325134931
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Parva	ENSMUSG00000030770	0.347639524025037	0.347639524025037	0.17750354896016	0.347639524025037	0.244170096021948	0.347639524025037
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Grlf1	ENSMUSG00000058230	0.386972299618399	0.711240436189781	0.573205482926791	0.711240436189781	0.711240436189781	0.711240436189781
Cav3	ENSMUSG00000062694	0.643359829732651	0.643359829732651	0.141500034183268	0.424500102549803	0.400265374208515	0.600398061312773
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037
Flnc	ENSMUSG00000068699	0.852395395941406	0.852395395941406	0.118409250205154	0.355227750615461	0.576973746230334	0.852395395941406
Ppp1r12b	ENSMUSG00000073557	0.577829325134931	0.578113371816017	0.0953125666339397	0.285937699901819	0.578113371816017	0.578113371816017
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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ECM-receptor interaction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041
Frem2	ENSMUSG00000037016	0.710001140920767	0.710001140920767	0.294820734456232	0.710001140920767	0.643853282854191	0.710001140920767
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Sv2b	ENSMUSG00000053025	0.295201212209107	0.516994836448954	0.344663224299303	0.516994836448954	0.92616891281798	0.92616891281798
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Arrhythmogenic right ventricular cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Lmna	ENSMUSG00000028063	0.452880492349546	0.575536202757516	0.575536202757516	0.575536202757516	0.5155648232968	0.575536202757516
Sgcb	ENSMUSG00000029156	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343	0.578113371816017	0.578113371816017
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Cacna2d1	ENSMUSG00000040118	0.004593575623324	0.013780726869972	0.298974794311434	0.448462191467151	0.454258017332816	0.454258017332816
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Ctnna2	ENSMUSG00000063063	0.345037391052887	0.51755608657933	0.299722768420014	0.51755608657933	0.575536202757516	0.575536202757516
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Dilated cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tgfb3	ENSMUSG00000021253	0.853480389728993	0.853480389728993	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Lmna	ENSMUSG00000028063	0.452880492349546	0.575536202757516	0.575536202757516	0.575536202757516	0.5155648232968	0.575536202757516
Sgcb	ENSMUSG00000029156	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343	0.578113371816017	0.578113371816017
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Cacna2d1	ENSMUSG00000040118	0.004593575623324	0.013780726869972	0.298974794311434	0.448462191467151	0.454258017332816	0.454258017332816
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Axon guidance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Smo	ENSMUSG00000001761	0.214764523938594	0.322146785907891	0.144820068500793	0.322146785907891	0.847921313356738	0.847921313356738
Efnb3	ENSMUSG00000003934	0.0743693776059065	0.223108132817719	0.780851835278817	0.926441990075769	0.926441990075769	0.926441990075769
Rac3	ENSMUSG00000018012	0.450794830295118	0.684457862089655	0.456305241393103	0.684457862089655	0.711034989117171	0.711034989117171
Ntn1	ENSMUSG00000020902	0.575536202757516	0.575536202757516	0.0964252305385473	0.289275691615642	0.399548817627028	0.575536202757516
Wnt5a	ENSMUSG00000021994	1	1	0.044737329683373	0.134211989050119	0.78180291566155	1
Sema5a	ENSMUSG00000022231	0.640355507848752	0.640355507848752	0.216214347033995	0.640355507848752	0.45596561163947	0.640355507848752
Boc	ENSMUSG00000022687	0.642117186565222	0.643606811957488	0.297472133192261	0.643606811957488	0.643606811957488	0.643606811957488
Enah	ENSMUSG00000022995	0.216214347033995	0.450143880930327	0.577259514257969	0.577259514257969	0.300095920620218	0.450143880930327
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Plxnb3	ENSMUSG00000031385	0.298974794311434	0.852723421673413	0.643112334413352	0.852723421673413	0.852723421673413	0.852723421673413
Ryk	ENSMUSG00000032547	0.852940894477647	0.852940894477647	0.348008842235184	0.522013263352777	0.254414773803597	0.522013263352777
Sema6c	ENSMUSG00000038777	0.926333123228344	0.926333123228344	0.211110344399808	0.633331033199424	0.711854160331342	0.926333123228344
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1
Sema5b	ENSMUSG00000052133	0.081631317865244	0.244893953595732	0.29367586332188	0.440513794982821	1	1
Sema3b	ENSMUSG00000057969	0.780851835278818	0.780851835278818	0.7802108304765	0.780851835278818	0.400265374208515	0.780851835278818
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037

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PI3K-Akt signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Gys1	ENSMUSG00000003865	0.513665062682276	0.513665062682276	0.0761127945805735	0.228338383741721	0.392985378348026	0.513665062682276
Kit	ENSMUSG00000005672	0.299349060054895	0.449023590082343	0.0761127945805736	0.228338383741721	0.642864324224729	0.642864324224729
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Ppp2r2b	ENSMUSG00000024500	0.120850531362929	0.270440003940477	0.180293335960318	0.270440003940477	0.453225835454266	0.453225835454266
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Pkn3	ENSMUSG00000026785	0.454942951775341	0.770497594023414	0.513665062682276	0.770497594023414	0.781170242226513	0.781170242226513
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Gnb4	ENSMUSG00000027669	0.0936419271039906	0.140462890655986	0.0419238354397911	0.125771506319373	0.926658283600152	0.926658283600152
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041
Chrm2	ENSMUSG00000045613	0.45596561163947	0.683948417459205	0.297848640636702	0.683948417459205	0.926333123228344	0.926333123228344
F2r	ENSMUSG00000048376	0.5155648232968	0.5155648232968	0.0761127945805736	0.228338383741721	0.346527959006435	0.5155648232968
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Ghr	ENSMUSG00000055737	0.298599969973533	0.298599969973533	0.119631084167592	0.21723010275119	0.144820068500793	0.21723010275119
Irs1	ENSMUSG00000055980	0.711650020253571	0.711650020253571	0.0741204440774082	0.113048158029898	0.0753654386865987	0.113048158029898
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Hypertrophic cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tgfb3	ENSMUSG00000021253	0.853480389728993	0.853480389728993	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Lmna	ENSMUSG00000028063	0.452880492349546	0.575536202757516	0.575536202757516	0.575536202757516	0.5155648232968	0.575536202757516
Sgcb	ENSMUSG00000029156	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343	0.578113371816017	0.578113371816017
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Cacna2d1	ENSMUSG00000040118	0.004593575623324	0.013780726869972	0.298974794311434	0.448462191467151	0.454258017332816	0.454258017332816
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Circadian entrainment

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gria3	ENSMUSG00000001986	0.926333123228344	0.926333123228344	0.0579478375430677	0.173843512629203	0.635703516568382	0.926333123228344
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Gria4	ENSMUSG00000025892	0.578113371816017	0.867170057724026	0.576973746230334	0.867170057724026	0.926658283600152	0.926658283600152
Gnb4	ENSMUSG00000027669	0.0936419271039906	0.140462890655986	0.0419238354397911	0.125771506319373	0.926658283600152	0.926658283600152
Gucy1b3	ENSMUSG00000028005	0.39335551479284	0.39335551479284	0.119325847749354	0.307200086216135	0.204800057477424	0.307200086216135
Nos1	ENSMUSG00000029361	0.7802108304765	0.7802108304765	0.179945789077372	0.269918683616058	0.0761127945805735	0.228338383741721
Adcyap1r1	ENSMUSG00000029778	0.346156228791382	0.519234343187073	0.0572923876732158	0.171877163019648	0.925948247631505	0.925948247631505
Gnao1	ENSMUSG00000031748	0.201408665602973	0.30211299840446	0.178901132102685	0.30211299840446	0.776243028387552	0.776243028387552
Gucy1a3	ENSMUSG00000033910	0.643359829732651	0.782117202022501	0.119631084167591	0.358893252502774	0.782117202022501	0.782117202022501
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Prkg1	ENSMUSG00000052920	0.392243127063687	0.675667401277161	0.710416009055326	0.710416009055326	0.450444934184774	0.675667401277161

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Human papillomavirus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Hey2	ENSMUSG00000019789	0.213307944885796	0.213307944885796	0.148772260628989	0.213307944885796	0.0562022152993845	0.168606645898153
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Wnt5a	ENSMUSG00000021994	1	1	0.044737329683373	0.134211989050119	0.78180291566155	1
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Ppp2r2b	ENSMUSG00000024500	0.120850531362929	0.270440003940477	0.180293335960318	0.270440003940477	0.453225835454266	0.453225835454266
Itga7	ENSMUSG00000025348	0.451840588205062	0.640861491578951	0.0936419271039908	0.280925781311972	0.640861491578951	0.640861491578951
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Ptgs2	ENSMUSG00000032487	0.216214347033995	0.383295497001398	0.711854160331342	0.711854160331342	0.255530331334266	0.383295497001398
Heyl	ENSMUSG00000032744	0.113498953177704	0.340496859533111	1	1	0.300095920620218	0.450143880930327
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041
Fzd8	ENSMUSG00000036904	0.640101714462795	0.640101714462795	0.249528554620971	0.588921874596118	0.392614583064079	0.588921874596118
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Maml3	ENSMUSG00000061143	0.853694531487825	0.853694531487825	0.781011212316137	0.853694531487825	0.514617706526787	0.853694531487825
Inadl	ENSMUSG00000061859	0.456305241393103	0.456305241393103	0.452880492349546	0.456305241393103	0.299349060054896	0.456305241393103
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Amoebiasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Actn1	ENSMUSG00000015143	0.513665062682276	0.640861491578951	0.451840588205062	0.640861491578951	0.640861491578951	0.640861491578951
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tgfb3	ENSMUSG00000021253	0.853480389728993	0.853480389728993	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343
Vcl	ENSMUSG00000021823	0.17924968721805	0.537749061654149	0.78180291566155	0.926658283600152	0.926658283600152	0.926658283600152
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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cAMP signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gria3	ENSMUSG00000001986	0.926333123228344	0.926333123228344	0.0579478375430677	0.173843512629203	0.635703516568382	0.926333123228344
Rac3	ENSMUSG00000018012	0.450794830295118	0.684457862089655	0.456305241393103	0.684457862089655	0.711034989117171	0.711034989117171
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Pde10a	ENSMUSG00000023868	0.398829756175299	0.398829756175299	0.343913050223227	0.398829756175299	0.023931046492469	0.071793139477407
Gria4	ENSMUSG00000025892	0.578113371816017	0.867170057724026	0.576973746230334	0.867170057724026	0.926658283600152	0.926658283600152
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Adcyap1r1	ENSMUSG00000029778	0.346156228791382	0.519234343187073	0.0572923876732158	0.171877163019648	0.925948247631505	0.925948247631505
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Chrm2	ENSMUSG00000045613	0.45596561163947	0.683948417459205	0.297848640636702	0.683948417459205	0.926333123228344	0.926333123228344
F2r	ENSMUSG00000048376	0.5155648232968	0.5155648232968	0.0761127945805736	0.228338383741721	0.346527959006435	0.5155648232968
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037

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cGMP-PKG signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kcnmb1	ENSMUSG00000020155	1	1	0.044926265292481	0.134778795877443	0.398829756175299	0.598244634262948
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Gucy1b3	ENSMUSG00000028005	0.39335551479284	0.39335551479284	0.119325847749354	0.307200086216135	0.204800057477424	0.307200086216135
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Gucy1a3	ENSMUSG00000033910	0.643359829732651	0.782117202022501	0.119631084167591	0.358893252502774	0.782117202022501	0.782117202022501
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Prkg1	ENSMUSG00000052920	0.392243127063687	0.675667401277161	0.710416009055326	0.710416009055326	0.450444934184774	0.675667401277161
Irs1	ENSMUSG00000055980	0.711650020253571	0.711650020253571	0.0741204440774082	0.113048158029898	0.0753654386865987	0.113048158029898
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Adrenergic signaling in cardiomyocytes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Ppp1r1a	ENSMUSG00000022490	1	1	0.455284468727762	0.682926703091643	0.144489143676808	0.433467431030423
Ppp2r2b	ENSMUSG00000024500	0.120850531362929	0.270440003940477	0.180293335960318	0.270440003940477	0.453225835454266	0.453225835454266
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Cacna2d1	ENSMUSG00000040118	0.004593575623324	0.013780726869972	0.298974794311434	0.448462191467151	0.454258017332816	0.454258017332816
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Pathways in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Smo	ENSMUSG00000001761	0.214764523938594	0.322146785907891	0.144820068500793	0.322146785907891	0.847921313356738	0.847921313356738
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Kit	ENSMUSG00000005672	0.299349060054895	0.449023590082343	0.0761127945805736	0.228338383741721	0.642864324224729	0.642864324224729
Rac3	ENSMUSG00000018012	0.450794830295118	0.684457862089655	0.456305241393103	0.684457862089655	0.711034989117171	0.711034989117171
Ptger1	ENSMUSG00000019464	0.148772260628989	0.223158390943484	0.0443599545252853	0.133079863575856	0.92622377157404	0.92622377157404
Hey2	ENSMUSG00000019789	0.213307944885796	0.213307944885796	0.148772260628989	0.213307944885796	0.0562022152993845	0.168606645898153
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tgfb3	ENSMUSG00000021253	0.853480389728993	0.853480389728993	0.254787123615605	0.449023590082343	0.299349060054895	0.449023590082343
Dapk1	ENSMUSG00000021559	0.454600801949285	0.643853282854191	0.643853282854191	0.643853282854191	0.578113371816017	0.643853282854191
Wnt5a	ENSMUSG00000021994	1	1	0.044737329683373	0.134211989050119	0.78180291566155	1
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Gnb4	ENSMUSG00000027669	0.0936419271039906	0.140462890655986	0.0419238354397911	0.125771506319373	0.926658283600152	0.926658283600152
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Ret	ENSMUSG00000030110	0.578396848531894	0.642366752097095	0.642366752097095	0.642366752097095	0.178901132102685	0.536703396308054
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Ptgs2	ENSMUSG00000032487	0.216214347033995	0.383295497001398	0.711854160331342	0.711854160331342	0.255530331334266	0.383295497001398
Heyl	ENSMUSG00000032744	0.113498953177704	0.340496859533111	1	1	0.300095920620218	0.450143880930327
Fzd8	ENSMUSG00000036904	0.640101714462795	0.640101714462795	0.249528554620971	0.588921874596118	0.392614583064079	0.588921874596118
F2r	ENSMUSG00000048376	0.5155648232968	0.5155648232968	0.0761127945805736	0.228338383741721	0.346527959006435	0.5155648232968
Gli2	ENSMUSG00000048402	0.781960228679124	0.926604389137101	0.926604389137101	0.926604389137101	0.179597906187076	0.538793718561228
Kif7	ENSMUSG00000050382	0.0964252305385472	0.289275691615642	0.398829756175299	0.398829756175299	0.210374401237615	0.315561601856423
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Alk	ENSMUSG00000055471	0.710416009055326	0.710416009055326	0.576400475350273	0.710416009055326	0.710416009055326	0.710416009055326
Ctnna2	ENSMUSG00000063063	0.345037391052887	0.51755608657933	0.299722768420014	0.51755608657933	0.575536202757516	0.575536202757516
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Mannose type O-glycan biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
B4galt2	ENSMUSG00000028541	0.578113371816017	0.642366752097095	0.178901132102685	0.536703396308054	0.642366752097095	0.642366752097095
Mgat5b	ENSMUSG00000043857	0.778088064569037	0.780371608729617	0.780371608729617	0.780371608729617	0.637533938625025	0.780371608729617
B3gat1	ENSMUSG00000045994	1	1	0.851398010388928	1	0.153667786000159	0.461003358000476
Fut9	ENSMUSG00000055373	0.538583409679131	0.538583409679131	0.538583409679131	0.538583409679131	0.538583409679131	0.538583409679131

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Small cell lung cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Ptgs2	ENSMUSG00000032487	0.216214347033995	0.383295497001398	0.711854160331342	0.711854160331342	0.255530331334266	0.383295497001398
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Extracellular matrix organization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
P4ha2	ENSMUSG00000018906	0.058823267388015	0.175777610154895	0.117185073436597	0.175777610154895	0.447265995733381	0.447265995733381
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
P4ha1	ENSMUSG00000019916	0.0958690133561599	0.270440003940477	0.180293335960318	0.270440003940477	0.399548817627028	0.399548817627028
Pxdn	ENSMUSG00000020674	0.252920381501207	0.37938057225181	0.0902955323751899	0.27088659712557	0.92622377157404	0.92622377157404
Leprel2	ENSMUSG00000023191	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	0.850721744111585	0.850721744111585
Ltbp3	ENSMUSG00000024940	0.642117186565222	0.853587578053106	0.0520879742179454	0.156263922653836	0.853587578053106	0.853587578053106
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Capn2	ENSMUSG00000026509	0.577829325134931	0.577829325134931	0.454942951775341	0.577829325134931	0.572616808177226	0.577829325134931
Ddr2	ENSMUSG00000026674	0.120850531362929	0.221188136557642	0.147458757705094	0.221188136557642	0.513665062682276	0.513665062682276
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Fbn1	ENSMUSG00000027204	0.345410946355104	0.518116419532656	0.21549027811633	0.518116419532656	0.711854160331342	0.711854160331342
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041
Loxl2	ENSMUSG00000034205	0.926658283600152	0.926658283600152	0.174692232033629	0.524076696100887	0.643853282854191	0.926658283600152
Adamts2	ENSMUSG00000036545	0.456305241393103	0.456305241393103	0.0763619660358786	0.229085898107636	0.45596561163947	0.456305241393103
Leprel1	ENSMUSG00000038168	0.7802108304765	0.7802108304765	0.297095062262362	0.521459286037555	0.347639524025037	0.521459286037555
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Jam2	ENSMUSG00000053062	0.45596561163947	0.643359829732651	0.180293335960318	0.540880007880955	0.643359829732651	0.643359829732651
Spock3	ENSMUSG00000054162	0.853694531487825	0.853694531487825	0.711854160331342	0.853694531487825	0.711240436189781	0.853694531487825
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col28a1	ENSMUSG00000068794	0.255530331334266	0.766590994002797	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Nervous system development

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tubb6	ENSMUSG00000001473	0.711034989117171	0.711034989117171	0.0723789610264069	0.217136883079221	0.577259514257969	0.711034989117171
Efnb3	ENSMUSG00000003934	0.0743693776059065	0.223108132817719	0.780851835278817	0.926441990075769	0.926441990075769	0.926441990075769
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Grb10	ENSMUSG00000020176	0.642366752097095	0.78180291566155	0.0743693776059064	0.223108132817719	0.78180291566155	0.78180291566155
Ntn1	ENSMUSG00000020902	0.575536202757516	0.575536202757516	0.0964252305385473	0.289275691615642	0.399548817627028	0.575536202757516
Enah	ENSMUSG00000022995	0.216214347033995	0.450143880930327	0.577259514257969	0.577259514257969	0.300095920620218	0.450143880930327
Gfra1	ENSMUSG00000025089	0.643853282854191	0.853372965654504	0.853372965654504	0.853372965654504	0.5155648232968	0.853372965654504
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Gfra4	ENSMUSG00000027316	0.5155648232968	0.711854160331342	0.023800255149993	0.0714007654499789	0.711854160331342	0.711854160331342
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Ret	ENSMUSG00000030110	0.578396848531894	0.642366752097095	0.642366752097095	0.642366752097095	0.178901132102685	0.536703396308054
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Plxnb3	ENSMUSG00000031385	0.298974794311434	0.852723421673413	0.643112334413352	0.852723421673413	0.852723421673413	0.852723421673413
Ank1	ENSMUSG00000031543	0.213307944885796	0.324321520550992	0.710208797518812	0.710208797518812	0.216214347033995	0.324321520550992
Gpr126	ENSMUSG00000039116	0.574375606171923	0.863304304136274	0.575536202757516	0.863304304136274	1	1
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1
Cntn2	ENSMUSG00000053024	1	1	0.254414773803597	0.763244321410791	0.853157406788312	1
Grlf1	ENSMUSG00000058230	0.386972299618399	0.711240436189781	0.573205482926791	0.711240436189781	0.711240436189781	0.711240436189781
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342
Tuba1a	ENSMUSG00000072235	1	1	0.17610058307789	0.52830174923367	0.57113445032749	0.856701675491234
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Axon guidance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tubb6	ENSMUSG00000001473	0.711034989117171	0.711034989117171	0.0723789610264069	0.217136883079221	0.577259514257969	0.711034989117171
Efnb3	ENSMUSG00000003934	0.0743693776059065	0.223108132817719	0.780851835278817	0.926441990075769	0.926441990075769	0.926441990075769
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Grb10	ENSMUSG00000020176	0.642366752097095	0.78180291566155	0.0743693776059064	0.223108132817719	0.78180291566155	0.78180291566155
Ntn1	ENSMUSG00000020902	0.575536202757516	0.575536202757516	0.0964252305385473	0.289275691615642	0.399548817627028	0.575536202757516
Enah	ENSMUSG00000022995	0.216214347033995	0.450143880930327	0.577259514257969	0.577259514257969	0.300095920620218	0.450143880930327
Gfra1	ENSMUSG00000025089	0.643853282854191	0.853372965654504	0.853372965654504	0.853372965654504	0.5155648232968	0.853372965654504
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Gfra4	ENSMUSG00000027316	0.5155648232968	0.711854160331342	0.023800255149993	0.0714007654499789	0.711854160331342	0.711854160331342
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Ret	ENSMUSG00000030110	0.578396848531894	0.642366752097095	0.642366752097095	0.642366752097095	0.178901132102685	0.536703396308054
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Plxnb3	ENSMUSG00000031385	0.298974794311434	0.852723421673413	0.643112334413352	0.852723421673413	0.852723421673413	0.852723421673413
Ank1	ENSMUSG00000031543	0.213307944885796	0.324321520550992	0.710208797518812	0.710208797518812	0.216214347033995	0.324321520550992
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1
Cntn2	ENSMUSG00000053024	1	1	0.254414773803597	0.763244321410791	0.853157406788312	1
Grlf1	ENSMUSG00000058230	0.386972299618399	0.711240436189781	0.573205482926791	0.711240436189781	0.711240436189781	0.711240436189781
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342
Tuba1a	ENSMUSG00000072235	1	1	0.17610058307789	0.52830174923367	0.57113445032749	0.856701675491234
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Collagen biosynthesis and modifying enzymes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
P4ha2	ENSMUSG00000018906	0.058823267388015	0.175777610154895	0.117185073436597	0.175777610154895	0.447265995733381	0.447265995733381
P4ha1	ENSMUSG00000019916	0.0958690133561599	0.270440003940477	0.180293335960318	0.270440003940477	0.399548817627028	0.399548817627028
Leprel2	ENSMUSG00000023191	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	0.850721744111585	0.850721744111585
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Adamts2	ENSMUSG00000036545	0.456305241393103	0.456305241393103	0.0763619660358786	0.229085898107636	0.45596561163947	0.456305241393103
Leprel1	ENSMUSG00000038168	0.7802108304765	0.7802108304765	0.297095062262362	0.521459286037555	0.347639524025037	0.521459286037555
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col28a1	ENSMUSG00000068794	0.255530331334266	0.766590994002797	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Collagen formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
P4ha2	ENSMUSG00000018906	0.058823267388015	0.175777610154895	0.117185073436597	0.175777610154895	0.447265995733381	0.447265995733381
P4ha1	ENSMUSG00000019916	0.0958690133561599	0.270440003940477	0.180293335960318	0.270440003940477	0.399548817627028	0.399548817627028
Pxdn	ENSMUSG00000020674	0.252920381501207	0.37938057225181	0.0902955323751899	0.27088659712557	0.92622377157404	0.92622377157404
Leprel2	ENSMUSG00000023191	0.216214347033995	0.593892267963669	0.395928178642446	0.593892267963669	0.850721744111585	0.850721744111585
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Loxl2	ENSMUSG00000034205	0.926658283600152	0.926658283600152	0.174692232033629	0.524076696100887	0.643853282854191	0.926658283600152
Adamts2	ENSMUSG00000036545	0.456305241393103	0.456305241393103	0.0763619660358786	0.229085898107636	0.45596561163947	0.456305241393103
Leprel1	ENSMUSG00000038168	0.7802108304765	0.7802108304765	0.297095062262362	0.521459286037555	0.347639524025037	0.521459286037555
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col28a1	ENSMUSG00000068794	0.255530331334266	0.766590994002797	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Muscle contraction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Vcl	ENSMUSG00000021823	0.17924968721805	0.537749061654149	0.78180291566155	0.926658283600152	0.926658283600152	0.926658283600152
Kcnip2	ENSMUSG00000025221	0.511742979522636	0.511742979522636	0.0331400397096515	0.0497100595644772	0.00755778364492931	0.0226733509347879
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Tmod1	ENSMUSG00000028328	0.0328221470541517	0.0984664411624552	1	1	0.0716332429957516	0.107449864493627
Nos1	ENSMUSG00000029361	0.7802108304765	0.7802108304765	0.179945789077372	0.269918683616058	0.0761127945805735	0.228338383741721
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Abcc9	ENSMUSG00000030249	0.345410946355104	0.518116419532656	0.254414773803597	0.518116419532656	0.779888212132595	0.779888212132595
Dmpk	ENSMUSG00000030409	0.119631084167592	0.179446626251387	0.0171027900598199	0.0513083701794598	0.299349060054895	0.299349060054895
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cav3	ENSMUSG00000062694	0.643359829732651	0.643359829732651	0.141500034183268	0.424500102549803	0.400265374208515	0.600398061312773
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Scn2b	ENSMUSG00000070304	0.0961471511181028	0.288441453354308	0.252545530864481	0.378818296296721	0.515249728559994	0.515249728559994
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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MET promotes cell motility

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tns3	ENSMUSG00000020422	0.780851835278818	0.780851835278818	0.337435786255283	0.599323226440542	0.399548817627028	0.599323226440542
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041

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MET activates PTK2 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041

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Signaling by PDGF

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Ion homeostasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Nos1	ENSMUSG00000029361	0.7802108304765	0.7802108304765	0.179945789077372	0.269918683616058	0.0761127945805735	0.228338383741721
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Abcc9	ENSMUSG00000030249	0.345410946355104	0.518116419532656	0.254414773803597	0.518116419532656	0.779888212132595	0.779888212132595
Dmpk	ENSMUSG00000030409	0.119631084167592	0.179446626251387	0.0171027900598199	0.0513083701794598	0.299349060054895	0.299349060054895
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Cardiac conduction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ryr2	ENSMUSG00000021313	0.0562022152993845	0.168606645898153	0.710001140920767	0.92589277149125	0.92589277149125	0.92589277149125
Kcnip2	ENSMUSG00000025221	0.511742979522636	0.511742979522636	0.0331400397096515	0.0497100595644772	0.00755778364492931	0.0226733509347879
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Nos1	ENSMUSG00000029361	0.7802108304765	0.7802108304765	0.179945789077372	0.269918683616058	0.0761127945805735	0.228338383741721
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Abcc9	ENSMUSG00000030249	0.345410946355104	0.518116419532656	0.254414773803597	0.518116419532656	0.779888212132595	0.779888212132595
Dmpk	ENSMUSG00000030409	0.119631084167592	0.179446626251387	0.0171027900598199	0.0513083701794598	0.299349060054895	0.299349060054895
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Pln	ENSMUSG00000038583	0.576973746230334	0.576973746230334	0.0746183450292887	0.220200812784373	0.146800541856249	0.220200812784373
Cacna1c	ENSMUSG00000051331	0.299349060054895	0.898047180164686	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769
Cacng7	ENSMUSG00000069806	0.853480389728993	0.853480389728993	0.577829325134931	0.853480389728993	0.514934023620345	0.853480389728993
Scn2b	ENSMUSG00000070304	0.0961471511181028	0.288441453354308	0.252545530864481	0.378818296296721	0.515249728559994	0.515249728559994
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Integrin cell surface interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Fbn1	ENSMUSG00000027204	0.345410946355104	0.518116419532656	0.21549027811633	0.518116419532656	0.711854160331342	0.711854160331342
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Jam2	ENSMUSG00000053062	0.45596561163947	0.643359829732651	0.180293335960318	0.540880007880955	0.643359829732651	0.643359829732651
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Non-integrin membrane-ECM interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Ddr2	ENSMUSG00000026674	0.120850531362929	0.221188136557642	0.147458757705094	0.221188136557642	0.513665062682276	0.513665062682276
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Laminin interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Signaling by MET

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Tns3	ENSMUSG00000020422	0.780851835278818	0.780851835278818	0.337435786255283	0.599323226440542	0.399548817627028	0.599323226440542
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Lrig1	ENSMUSG00000030029	0.78180291566155	0.78180291566155	0.144157978128026	0.432473934384077	0.710001140920767	0.78180291566155
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041

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Platelet homeostasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
P2rx6	ENSMUSG00000022758	0.454942951775341	0.514934023620344	0.0953125666339396	0.285937699901819	0.514934023620344	0.514934023620344
Pde10a	ENSMUSG00000023868	0.398829756175299	0.398829756175299	0.343913050223227	0.398829756175299	0.023931046492469	0.071793139477407
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Gnb4	ENSMUSG00000027669	0.0936419271039906	0.140462890655986	0.0419238354397911	0.125771506319373	0.926658283600152	0.926658283600152
Nos1	ENSMUSG00000029361	0.7802108304765	0.7802108304765	0.179945789077372	0.269918683616058	0.0761127945805735	0.228338383741721
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Prkg1	ENSMUSG00000052920	0.392243127063687	0.675667401277161	0.710416009055326	0.710416009055326	0.450444934184774	0.675667401277161
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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NCAM signaling for neurite out-growth

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Reduction of cytosolic Ca++ levels

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Signaling by Receptor Tyrosine Kinases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Kit	ENSMUSG00000005672	0.299349060054895	0.449023590082343	0.0761127945805736	0.228338383741721	0.642864324224729	0.642864324224729
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Ptprk	ENSMUSG00000019889	0.710001140920767	0.710001140920767	0.569937449249116	0.710001140920767	0.50716883916608	0.710001140920767
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Grb10	ENSMUSG00000020176	0.642366752097095	0.78180291566155	0.0743693776059064	0.223108132817719	0.78180291566155	0.78180291566155
Tns3	ENSMUSG00000020422	0.780851835278818	0.780851835278818	0.337435786255283	0.599323226440542	0.399548817627028	0.599323226440542
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Nrp2	ENSMUSG00000025969	0.782117202022501	0.782117202022501	0.120545895661628	0.361637686984883	0.514934023620345	0.772401035430517
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Klb	ENSMUSG00000029195	0.577544706586058	0.852832278580641	0.642117186565222	0.852832278580641	0.852832278580641	0.852832278580641
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Wasf3	ENSMUSG00000029636	0.515249728559994	0.643112334413352	0.643112334413352	0.643112334413352	0.0586042534833403	0.175812760450021
Lrig1	ENSMUSG00000030029	0.78180291566155	0.78180291566155	0.144157978128026	0.432473934384077	0.710001140920767	0.78180291566155
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Rbfox2	ENSMUSG00000033565	0.643359829732651	0.777922216623952	0.634645058916812	0.777922216623952	0.777922216623952	0.777922216623952
Wwp1	ENSMUSG00000041058	0.14712977154559	0.441389314636769	0.344663224299303	0.516994836448954	0.926604389137101	0.926604389137101
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Platelet calcium homeostasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
P2rx6	ENSMUSG00000022758	0.454942951775341	0.514934023620344	0.0953125666339396	0.285937699901819	0.514934023620344	0.514934023620344
Atp2b4	ENSMUSG00000026463	0.348008842235184	0.348008842235184	0.120850531362929	0.348008842235184	0.344663224299303	0.348008842235184
Atp2a2	ENSMUSG00000029467	0.400265374208515	0.681901202923927	0.454600801949285	0.681901202923927	0.85117361048289	0.85117361048289
Atp2a1	ENSMUSG00000030730	0.01710279005982	0.0513083701794599	0.297095062262363	0.297095062262363	0.0447373296833729	0.0671059945250594
Slc8a3	ENSMUSG00000079055	0.643112334413352	0.643606811957488	0.0967032506702096	0.290109752010629	0.643606811957488	0.643606811957488

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Developmental Biology

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tubb6	ENSMUSG00000001473	0.711034989117171	0.711034989117171	0.0723789610264069	0.217136883079221	0.577259514257969	0.711034989117171
Efnb3	ENSMUSG00000003934	0.0743693776059065	0.223108132817719	0.780851835278817	0.926441990075769	0.926441990075769	0.926441990075769
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Grb10	ENSMUSG00000020176	0.642366752097095	0.78180291566155	0.0743693776059064	0.223108132817719	0.78180291566155	0.78180291566155
Ntn1	ENSMUSG00000020902	0.575536202757516	0.575536202757516	0.0964252305385473	0.289275691615642	0.399548817627028	0.575536202757516
Enah	ENSMUSG00000022995	0.216214347033995	0.450143880930327	0.577259514257969	0.577259514257969	0.300095920620218	0.450143880930327
Gfra1	ENSMUSG00000025089	0.643853282854191	0.853372965654504	0.853372965654504	0.853372965654504	0.5155648232968	0.853372965654504
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Gfra4	ENSMUSG00000027316	0.5155648232968	0.711854160331342	0.023800255149993	0.0714007654499789	0.711854160331342	0.711854160331342
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Ret	ENSMUSG00000030110	0.578396848531894	0.642366752097095	0.642366752097095	0.642366752097095	0.178901132102685	0.536703396308054
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Plxnb3	ENSMUSG00000031385	0.298974794311434	0.852723421673413	0.643112334413352	0.852723421673413	0.852723421673413	0.852723421673413
Ank1	ENSMUSG00000031543	0.213307944885796	0.324321520550992	0.710208797518812	0.710208797518812	0.216214347033995	0.324321520550992
Gpr126	ENSMUSG00000039116	0.574375606171923	0.863304304136274	0.575536202757516	0.863304304136274	1	1
Lgi2	ENSMUSG00000039252	0.708323672944427	0.78132892626786	0.395562602091096	0.78132892626786	0.78132892626786	0.78132892626786
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1
Cntn2	ENSMUSG00000053024	1	1	0.254414773803597	0.763244321410791	0.853157406788312	1
Grlf1	ENSMUSG00000058230	0.386972299618399	0.711240436189781	0.573205482926791	0.711240436189781	0.711240436189781	0.711240436189781
Ctnna2	ENSMUSG00000063063	0.345037391052887	0.51755608657933	0.299722768420014	0.51755608657933	0.575536202757516	0.575536202757516
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342
Tuba1a	ENSMUSG00000072235	1	1	0.17610058307789	0.52830174923367	0.57113445032749	0.856701675491234
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Collagen chain trimerization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col28a1	ENSMUSG00000068794	0.255530331334266	0.766590994002797	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Cell-extracellular matrix interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Actn1	ENSMUSG00000015143	0.513665062682276	0.640861491578951	0.451840588205062	0.640861491578951	0.640861491578951	0.640861491578951
Parva	ENSMUSG00000030770	0.347639524025037	0.347639524025037	0.17750354896016	0.347639524025037	0.244170096021948	0.347639524025037
Fermt2	ENSMUSG00000037712	0.578113371816017	0.78148726569172	0.211110344399808	0.633331033199424	0.78148726569172	0.78148726569172
Flnc	ENSMUSG00000068699	0.852395395941406	0.852395395941406	0.118409250205154	0.355227750615461	0.576973746230334	0.852395395941406

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Cell-Cell communication

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Actn1	ENSMUSG00000015143	0.513665062682276	0.640861491578951	0.451840588205062	0.640861491578951	0.640861491578951	0.640861491578951
Parva	ENSMUSG00000030770	0.347639524025037	0.347639524025037	0.17750354896016	0.347639524025037	0.244170096021948	0.347639524025037
Cdh11	ENSMUSG00000031673	0.711445446052875	0.711445446052875	0.709584486155936	0.711445446052875	0.641867098978198	0.711445446052875
Kirrel2	ENSMUSG00000036915	0.781011212316137	0.853372965654504	0.853372965654504	0.853372965654504	0.215127611919162	0.645382835757485
Fermt2	ENSMUSG00000037712	0.578113371816017	0.78148726569172	0.211110344399808	0.633331033199424	0.78148726569172	0.78148726569172
Sdk1	ENSMUSG00000039683	0.450794830295118	0.450794830295118	0.173632433887832	0.317766870502212	0.211844580334808	0.317766870502212
Kirrel	ENSMUSG00000041734	0.171503747555202	0.257255621332803	0.091411676944639	0.257255621332803	0.643359829732651	0.643359829732651
Cdh3	ENSMUSG00000061048	0.398469281729516	0.597703922594274	0.215127611919161	0.597703922594274	0.708323672944427	0.708323672944427
Flnc	ENSMUSG00000068699	0.852395395941406	0.852395395941406	0.118409250205154	0.355227750615461	0.576973746230334	0.852395395941406

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Crosslinking of collagen fibrils

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pxdn	ENSMUSG00000020674	0.252920381501207	0.37938057225181	0.0902955323751899	0.27088659712557	0.92622377157404	0.92622377157404
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Loxl2	ENSMUSG00000034205	0.926658283600152	0.926658283600152	0.174692232033629	0.524076696100887	0.643853282854191	0.926658283600152
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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ECM proteoglycans

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Vtn	ENSMUSG00000017344	0.578113371816017	0.578113371816017	0.0958690133561599	0.28760704006848	0.450444934184774	0.578113371816017
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Tnc	ENSMUSG00000028364	1	1	0.146800541856249	0.440401625568747	0.926658283600152	1
Tnxb	ENSMUSG00000033327	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.578113371816017	0.926550375688041

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Glycogen synthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gys1	ENSMUSG00000003865	0.513665062682276	0.513665062682276	0.0761127945805735	0.228338383741721	0.392985378348026	0.513665062682276
Pgm2l1	ENSMUSG00000030729	0.642366752097095	0.710416009055326	0.0109864933352154	0.0329594800056462	0.710416009055326	0.710416009055326
Ppp1r3c	ENSMUSG00000067279	0.179945789077372	0.269918683616058	0.0588232673880149	0.176469802164045	0.711854160331342	0.711854160331342

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Interaction between L1 and Ankyrins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Ank1	ENSMUSG00000031543	0.213307944885796	0.324321520550992	0.710208797518812	0.710208797518812	0.216214347033995	0.324321520550992
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342

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NCAM1 interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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EPHA-mediated growth cone collapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1

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Activation of AMPA receptors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gria3	ENSMUSG00000001986	0.926333123228344	0.926333123228344	0.0579478375430677	0.173843512629203	0.635703516568382	0.926333123228344
Gria4	ENSMUSG00000025892	0.578113371816017	0.867170057724026	0.576973746230334	0.867170057724026	0.926658283600152	0.926658283600152

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Glycogen metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gys1	ENSMUSG00000003865	0.513665062682276	0.513665062682276	0.0761127945805735	0.228338383741721	0.392985378348026	0.513665062682276
Pgm2l1	ENSMUSG00000030729	0.642366752097095	0.710416009055326	0.0109864933352154	0.0329594800056462	0.710416009055326	0.710416009055326
Agl	ENSMUSG00000033400	0.635703516568382	0.635703516568382	0.507830090867449	0.635703516568382	0.216214347033995	0.635703516568382
Ppp1r3c	ENSMUSG00000067279	0.179945789077372	0.269918683616058	0.0588232673880149	0.176469802164045	0.711854160331342	0.711854160331342

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Cell junction organization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Actn1	ENSMUSG00000015143	0.513665062682276	0.640861491578951	0.451840588205062	0.640861491578951	0.640861491578951	0.640861491578951
Parva	ENSMUSG00000030770	0.347639524025037	0.347639524025037	0.17750354896016	0.347639524025037	0.244170096021948	0.347639524025037
Cdh11	ENSMUSG00000031673	0.711445446052875	0.711445446052875	0.709584486155936	0.711445446052875	0.641867098978198	0.711445446052875
Fermt2	ENSMUSG00000037712	0.578113371816017	0.78148726569172	0.211110344399808	0.633331033199424	0.78148726569172	0.78148726569172
Sdk1	ENSMUSG00000039683	0.450794830295118	0.450794830295118	0.173632433887832	0.317766870502212	0.211844580334808	0.317766870502212
Cdh3	ENSMUSG00000061048	0.398469281729516	0.597703922594274	0.215127611919161	0.597703922594274	0.708323672944427	0.708323672944427
Flnc	ENSMUSG00000068699	0.852395395941406	0.852395395941406	0.118409250205154	0.355227750615461	0.576973746230334	0.852395395941406

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Assembly of collagen fibrils and other multimeric structures

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pxdn	ENSMUSG00000020674	0.252920381501207	0.37938057225181	0.0902955323751899	0.27088659712557	0.92622377157404	0.92622377157404
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Loxl2	ENSMUSG00000034205	0.926658283600152	0.926658283600152	0.174692232033629	0.524076696100887	0.643853282854191	0.926658283600152
Col8a1	ENSMUSG00000068196	0.643853282854191	0.643853282854191	0.0969812105731562	0.290943631719469	0.255901190956604	0.383851786434906
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816

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Signal Transduction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tubb6	ENSMUSG00000001473	0.711034989117171	0.711034989117171	0.0723789610264069	0.217136883079221	0.577259514257969	0.711034989117171
Smo	ENSMUSG00000001761	0.214764523938594	0.322146785907891	0.144820068500793	0.322146785907891	0.847921313356738	0.847921313356738
Lamb1	ENSMUSG00000002900	1	1	0.213307944885796	0.639923834657388	0.712057867818062	1
Kit	ENSMUSG00000005672	0.299349060054895	0.449023590082343	0.0761127945805736	0.228338383741721	0.642864324224729	0.642864324224729
Sptbn4	ENSMUSG00000011751	0.925837170483845	0.925837170483845	0.509471754007076	0.925837170483845	0.853801250889739	0.925837170483845
Amotl1	ENSMUSG00000013076	0.348008842235184	0.522013263352776	0.11993617140438	0.359808514213139	0.711650020253571	0.711650020253571
Pea15a	ENSMUSG00000013698	0.78180291566155	0.78180291566155	0.0334587898203824	0.100376369461147	0.640861491578951	0.78180291566155
Clip3	ENSMUSG00000013921	0.56903312490074	0.56903312490074	0.255530331334266	0.383295497001399	0.11993617140438	0.359808514213139
Rac3	ENSMUSG00000018012	0.450794830295118	0.684457862089655	0.456305241393103	0.684457862089655	0.711034989117171	0.711034989117171
Grb7	ENSMUSG00000019312	0.514934023620345	0.514934023620345	0.0441715176243983	0.132514552873195	0.348008842235184	0.514934023620345
Ptger1	ENSMUSG00000019464	0.148772260628989	0.223158390943484	0.0443599545252853	0.133079863575856	0.92622377157404	0.92622377157404
Ptprk	ENSMUSG00000019889	0.710001140920767	0.710001140920767	0.569937449249116	0.710001140920767	0.50716883916608	0.710001140920767
Lama2	ENSMUSG00000019899	0.455284468727762	0.455284468727762	0.343913050223227	0.455284468727762	0.398829756175299	0.455284468727762
Grb10	ENSMUSG00000020176	0.642366752097095	0.78180291566155	0.0743693776059064	0.223108132817719	0.78180291566155	0.78180291566155
Tns3	ENSMUSG00000020422	0.780851835278818	0.780851835278818	0.337435786255283	0.599323226440542	0.399548817627028	0.599323226440542
Rgs6	ENSMUSG00000021219	0.711650020253571	0.926550375688041	0.711034989117171	0.926550375688041	0.926550375688041	0.926550375688041
Thbs4	ENSMUSG00000021702	0.454942951775341	0.711650020253571	0.711650020253571	0.711650020253571	0.643359829732651	0.711650020253571
Vcl	ENSMUSG00000021823	0.17924968721805	0.537749061654149	0.78180291566155	0.926658283600152	0.926658283600152	0.926658283600152
Cab39l	ENSMUSG00000021981	0.852504981253341	0.853480389728993	0.346899083932133	0.853480389728993	0.853480389728993	0.853480389728993
Wnt5a	ENSMUSG00000021994	1	1	0.044737329683373	0.134211989050119	0.78180291566155	1
Nefl	ENSMUSG00000022055	0.455625354715449	0.643359829732651	0.643359829732651	0.643359829732651	0.0969812105731564	0.290943631719469
Khdrbs3	ENSMUSG00000022332	0.638824656785692	0.711240436189781	0.711240436189781	0.711240436189781	0.576973746230334	0.711240436189781
Dgkg	ENSMUSG00000022861	0.513026869856283	0.513026869856283	0.399548817627028	0.513026869856283	0.300095920620218	0.513026869856283
Pde10a	ENSMUSG00000023868	0.398829756175299	0.398829756175299	0.343913050223227	0.398829756175299	0.023931046492469	0.071793139477407
Thbs2	ENSMUSG00000023885	0.578396848531894	0.711034989117171	0.0315593554855452	0.0946780664566356	0.711034989117171	0.711034989117171
Guca1b	ENSMUSG00000023979	0.21549027811633	0.64647083434899	0.92622377157404	0.92622377157404	0.575536202757516	0.863304304136274
Grm8	ENSMUSG00000024211	0.244556206197971	0.513346277289108	0.452880492349546	0.513346277289108	0.513346277289108	0.513346277289108
Gfra1	ENSMUSG00000025089	0.643853282854191	0.853372965654504	0.853372965654504	0.853372965654504	0.5155648232968	0.853372965654504
Rdh5	ENSMUSG00000025350	0.45596561163947	0.683948417459205	0.0761127945805735	0.228338383741721	0.782117202022501	0.782117202022501
Cbx8	ENSMUSG00000025578	0.577829325134931	0.577829325134931	0.252545530864481	0.378818296296721	0.118714930081337	0.35614479024401
Arhgef9	ENSMUSG00000025656	0.455625354715449	0.455625354715449	0.0964252305385473	0.289275691615642	0.455625354715449	0.455625354715449
Cnksr2	ENSMUSG00000025658	0.711034989117171	1	1	1	0.711650020253571	1
Nrp2	ENSMUSG00000025969	0.782117202022501	0.782117202022501	0.120545895661628	0.361637686984883	0.514934023620345	0.772401035430517
Col5a2	ENSMUSG00000026042	1	1	0.0303111090728679	0.0909333272186038	0.642366752097095	0.963550128145642
Fn1	ENSMUSG00000026193	0.514934023620345	0.772401035430517	0.119631084167592	0.358893252502776	0.926550375688041	0.926550375688041
Rgs7	ENSMUSG00000026527	0.346899083932133	0.578113371816017	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Rgs5	ENSMUSG00000026678	0.0763619660358786	0.229085898107636	0.177853449259986	0.252920381501206	0.252920381501206	0.252920381501206
Pkn3	ENSMUSG00000026785	0.454942951775341	0.770497594023414	0.513665062682276	0.770497594023414	0.781170242226513	0.781170242226513
Col5a1	ENSMUSG00000026837	0.398829756175299	0.598244634262948	0.11595859961889	0.347875798856669	0.925669613555092	0.925669613555092
Lamc3	ENSMUSG00000026840	0.574375606171923	0.861563409257884	0.109483895726921	0.328451687180762	0.926278508226733	0.926278508226733
Gfra4	ENSMUSG00000027316	0.5155648232968	0.711854160331342	0.023800255149993	0.0714007654499789	0.711854160331342	0.711854160331342
Gnb4	ENSMUSG00000027669	0.0936419271039906	0.140462890655986	0.0419238354397911	0.125771506319373	0.926658283600152	0.926658283600152
Ect2	ENSMUSG00000027699	0.454600801949285	0.681901202923927	0.454600801949285	0.681901202923927	1	1
Smad9	ENSMUSG00000027796	0.575824878403157	0.575824878403157	0.179945789077372	0.269918683616058	0.148115998140416	0.269918683616058
Wwtr1	ENSMUSG00000027803	0.347639524025037	0.521459286037555	0.254414773803597	0.521459286037555	0.643359829732651	0.643359829732651
Thbs3	ENSMUSG00000028047	0.300095920620218	0.514934023620344	0.514934023620344	0.514934023620344	0.455625354715449	0.514934023620344
Klb	ENSMUSG00000029195	0.577544706586058	0.852832278580641	0.642117186565222	0.852832278580641	0.852832278580641	0.852832278580641
Pdgfra	ENSMUSG00000029231	0.511097249598474	0.511097249598474	0.297095062262362	0.511097249598474	0.399548817627028	0.511097249598474
Cdk8	ENSMUSG00000029635	0.166489709738751	0.249734564608126	0.0947558980989551	0.249734564608126	1	1
Wasf3	ENSMUSG00000029636	0.515249728559994	0.643112334413352	0.643112334413352	0.643112334413352	0.0586042534833403	0.175812760450021
Adcyap1r1	ENSMUSG00000029778	0.346156228791382	0.519234343187073	0.0572923876732158	0.171877163019648	0.925948247631505	0.925948247631505
Lrig1	ENSMUSG00000030029	0.78180291566155	0.78180291566155	0.144157978128026	0.432473934384077	0.710001140920767	0.78180291566155
Ret	ENSMUSG00000030110	0.578396848531894	0.642366752097095	0.642366752097095	0.642366752097095	0.178901132102685	0.536703396308054
Ift122	ENSMUSG00000030323	0.707899741868332	0.707899741868332	0.341647690705446	0.599323226440542	0.399548817627028	0.599323226440542
Col4a5	ENSMUSG00000031274	0.299349060054895	0.449023590082343	0.0753654386865987	0.226096316059796	0.577259514257969	0.577259514257969
Arhgap6	ENSMUSG00000031355	0.706831781264722	0.926550375688041	0.7802108304765	0.926550375688041	0.926550375688041	0.926550375688041
Gnao1	ENSMUSG00000031748	0.201408665602973	0.30211299840446	0.178901132102685	0.30211299840446	0.776243028387552	0.776243028387552
Ryk	ENSMUSG00000032547	0.852940894477647	0.852940894477647	0.348008842235184	0.522013263352777	0.254414773803597	0.522013263352777
Arhgef17	ENSMUSG00000032875	0.853694531487825	1	0.573205482926791	1	1	1
Arhgap44	ENSMUSG00000033389	0.395562602091096	0.395562602091096	0.0167871584516597	0.0503614753549792	0.0577292451600847	0.086593867740127
Rbfox2	ENSMUSG00000033565	0.643359829732651	0.777922216623952	0.634645058916812	0.777922216623952	0.777922216623952	0.777922216623952
Pygo1	ENSMUSG00000034910	0.396657401350108	0.45391459600125	0.45391459600125	0.45391459600125	0.178203013181634	0.45391459600125
Rtkn	ENSMUSG00000034930	0.711854160331342	0.711854160331342	0.0230207752632622	0.0690623257897866	0.643359829732651	0.711854160331342
Dgkb	ENSMUSG00000036095	0.119631084167592	0.358893252502775	0.299349060054895	0.449023590082343	0.926658283600152	0.926658283600152
Fzd8	ENSMUSG00000036904	0.640101714462795	0.640101714462795	0.249528554620971	0.588921874596118	0.392614583064079	0.588921874596118
Reep2	ENSMUSG00000038555	0.853480389728993	0.853480389728993	0.214037080764326	0.321055621146488	0.179945789077372	0.321055621146488
Disp2	ENSMUSG00000040035	0.45596561163947	0.577829325134931	0.452880492349546	0.577829325134931	0.577829325134931	0.577829325134931
Wwp1	ENSMUSG00000041058	0.14712977154559	0.441389314636769	0.344663224299303	0.516994836448954	0.926604389137101	0.926604389137101
Cnr1	ENSMUSG00000044288	0.926658283600152	0.926658283600152	0.0447373296833731	0.134211989050119	0.853480389728993	0.926658283600152
Ackr3	ENSMUSG00000044337	0.853372965654504	1	0.710208797518812	1	1	1
Ackr2	ENSMUSG00000044534	0.572321560317547	0.777755996383525	0.51398322803049	0.777755996383525	0.777755996383525	0.777755996383525
Dact1	ENSMUSG00000044548	0.852832278580641	0.852832278580641	0.041737700208629	0.113048158029898	0.0753654386865987	0.113048158029898
Chrm2	ENSMUSG00000045613	0.45596561163947	0.683948417459205	0.297848640636702	0.683948417459205	0.926333123228344	0.926333123228344
Rhoj	ENSMUSG00000046768	0.57466664340579	0.853372965654504	0.577829325134931	0.853372965654504	0.853372965654504	0.853372965654504
F2r	ENSMUSG00000048376	0.5155648232968	0.5155648232968	0.0761127945805736	0.228338383741721	0.346527959006435	0.5155648232968
Gli2	ENSMUSG00000048402	0.781960228679124	0.926604389137101	0.926604389137101	0.926604389137101	0.179597906187076	0.538793718561228
Evc2	ENSMUSG00000050248	0.78180291566155	1	0.643359829732651	1	1	1
Lamb2	ENSMUSG00000052911	0.853907737111068	0.926550375688041	0.0741204440774082	0.222361332232225	0.926550375688041	0.926550375688041
Arhgap20	ENSMUSG00000053199	0.641616487517698	0.643606811957488	0.514617706526787	0.643606811957488	0.643606811957488	0.643606811957488
Grlf1	ENSMUSG00000058230	0.386972299618399	0.711240436189781	0.573205482926791	0.711240436189781	0.711240436189781	0.711240436189781
Maml3	ENSMUSG00000061143	0.853694531487825	0.853694531487825	0.781011212316137	0.853694531487825	0.514617706526787	0.853694531487825
Myl9	ENSMUSG00000067818	0.297848640636702	0.347639524025037	0.0328221470541517	0.098466441162455	0.347639524025037	0.347639524025037
Sptbn2	ENSMUSG00000067889	0.45596561163947	0.683948417459205	0.45596561163947	0.683948417459205	0.711854160331342	0.711854160331342
Rasal2	ENSMUSG00000070565	0.511742979522636	1	0.853049270252403	1	1	1
Tuba1a	ENSMUSG00000072235	1	1	0.17610058307789	0.52830174923367	0.57113445032749	0.856701675491234
Ppp1r12b	ENSMUSG00000073557	0.577829325134931	0.578113371816017	0.0953125666339397	0.285937699901819	0.578113371816017	0.578113371816017
Kif5a	ENSMUSG00000074657	0.926550375688041	0.926550375688041	0.400265374208515	0.7733472349452	0.5155648232968	0.7733472349452
Ackr4	ENSMUSG00000079355	0.211844580334808	0.317766870502212	0.0579478375430677	0.173843512629203	0.78180291566155	0.78180291566155
Col4a3	ENSMUSG00000079465	0.0753654386865987	0.226096316059796	0.346156228791382	0.454258017332816	0.454258017332816	0.454258017332816
Hist2h3c2	ENSMUSG00000081058	0.578113371816017	0.578113371816017	0.253294730253595	0.379942095380392	0.216214347033995	0.379942095380392

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EPH-ephrin mediated repulsion of cells

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Efnb3	ENSMUSG00000003934	0.0743693776059065	0.223108132817719	0.780851835278817	0.926441990075769	0.926441990075769	0.926441990075769
Efna3	ENSMUSG00000028039	0.575246939700399	0.578113371816017	0.252920381501206	0.578113371816017	0.578113371816017	0.578113371816017
Epha7	ENSMUSG00000028289	0.0592616003460511	0.177784801038153	0.346899083932133	0.520348625898199	0.926658283600152	0.926658283600152
Epha8	ENSMUSG00000028661	0.642366752097095	0.642366752097095	0.251794320496028	0.444508837538896	0.296339225025931	0.444508837538896
Efna5	ENSMUSG00000048915	1	1	0.781170242226513	1	0.451840588205062	1

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chocolate3

Cellular response to chemical stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sod2	ENSMUSG00000006818	0.453225835454266	0.772401035430517	0.514934023620345	0.772401035430517	0.926333123228344	0.926333123228344
Ero1l	ENSMUSG00000021831	0.509798138101151	0.764697207151727	0.850151080737202	0.850151080737202	0.399548817627028	0.764697207151727

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Detoxification of Reactive Oxygen Species

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sod2	ENSMUSG00000006818	0.453225835454266	0.772401035430517	0.514934023620345	0.772401035430517	0.926333123228344	0.926333123228344
Ero1l	ENSMUSG00000021831	0.509798138101151	0.764697207151727	0.850151080737202	0.850151080737202	0.399548817627028	0.764697207151727

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coral1

Glycerolipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dgke	ENSMUSG00000000276	0.342783164254397	0.709584486155936	0.709584486155936	0.709584486155936	0.706185359872137	0.709584486155936
Dgkq	ENSMUSG00000004815	0.85117361048289	0.926441990075769	0.926441990075769	0.926441990075769	0.508488713161374	0.926441990075769
Lpin2	ENSMUSG00000024052	0.072378961026407	0.179446626251387	0.119631084167592	0.179446626251387	0.711240436189781	0.711240436189781
Agpat2	ENSMUSG00000026922	0.120850531362929	0.181275797044394	0.11993617140438	0.181275797044394	0.926550375688041	0.926550375688041
Lpin3	ENSMUSG00000027412	0.399548817627028	0.853801250889739	0.642864324224729	0.853801250889739	0.853801250889739	0.853801250889739
Agk	ENSMUSG00000029916	0.0334587898203823	0.100376369461147	1	1	0.57113445032749	0.856701675491234
Ppapdc1b	ENSMUSG00000031570	0.776919261684345	0.776919261684345	0.252545530864481	0.446772960955053	0.297848640636702	0.446772960955053
Dgkz	ENSMUSG00000040479	0.78180291566155	0.78180291566155	0.711034989117171	0.78180291566155	0.5155648232968	0.78180291566155
Akr1b10	ENSMUSG00000061758	0.454600801949285	0.925444427431699	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699

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Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf3	ENSMUSG00000003184	0.711034989117171	0.781170242226513	0.781170242226513	0.781170242226513	0.45596561163947	0.781170242226513
Zfp354a	ENSMUSG00000020364	0.642864324224729	0.642864324224729	0.254414773803597	0.642864324224729	0.576973746230334	0.642864324224729
Alyref	ENSMUSG00000025134	0.0588232673880151	0.176469802164045	0.513665062682276	0.576973746230334	0.576973746230334	0.576973746230334
Zfp273	ENSMUSG00000030446	0.0936419271039906	0.280925781311972	0.643359829732651	0.643359829732651	0.295581119060361	0.443371678590541
Ikbkb	ENSMUSG00000031537	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343	0.211110344399808	0.449023590082343
Zfp90	ENSMUSG00000031907	0.853801250889739	0.853801250889739	0.711854160331342	0.853801250889739	0.397384062266614	0.853801250889739
Zfp551	ENSMUSG00000034071	0.505169133438821	0.757753700158231	1	1	0.25141795904251	0.754253877127531
Zfp707	ENSMUSG00000034429	0.924872384323463	0.924872384323463	0.255530331334266	0.383295497001399	0.213307944885796	0.383295497001399
Zfp956	ENSMUSG00000045466	0.0763619660358786	0.140462890655986	0.297848640636702	0.297848640636702	0.0936419271039908	0.140462890655986
Zfp454	ENSMUSG00000048728	0.121155015244363	0.181732522866545	0.577259514257969	0.577259514257969	0.121155015244363	0.181732522866545
Zfp112	ENSMUSG00000052675	0.711854160331342	0.711854160331342	0.711034989117171	0.711854160331342	0.5155648232968	0.711854160331342
Zfp952	ENSMUSG00000053390	0.711240436189781	0.711240436189781	0.578113371816017	0.711240436189781	0.514934023620345	0.711240436189781
Zfp867	ENSMUSG00000054519	0.78180291566155	0.78180291566155	0.5155648232968	0.78180291566155	0.711854160331342	0.78180291566155
Zfp667	ENSMUSG00000054893	0.398108175780842	0.398108175780842	0.211844580334808	0.317766870502212	0.0113901882503033	0.0341705647509098
Zfp180	ENSMUSG00000057101	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152	0.297848640636703	0.893545921910108
Zfp128	ENSMUSG00000060397	0.455284468727762	0.455284468727762	0.399189600887034	0.455284468727762	0.0445485589872461	0.133645676961738
Zfp873	ENSMUSG00000061371	0.926003599371282	0.926003599371282	0.642366752097095	0.926003599371282	0.119631084167592	0.358893252502775
Zfp780b	ENSMUSG00000063047	0.17610058307789	0.264150874616835	0.300095920620218	0.300095920620218	0.0958690133561599	0.264150874616835
Zfp810	ENSMUSG00000066829	0.0753654386865988	0.212250051274902	0.852065168704833	0.852065168704833	0.141500034183268	0.212250051274902
Zfp71-rs1	ENSMUSG00000071281	0.642366752097095	0.642366752097095	0.25141795904251	0.377126938563765	0.0579478375430677	0.173843512629203
Zfp788	ENSMUSG00000074165	0.926441990075769	0.926441990075769	0.299349060054895	0.683438032073173	0.455625354715449	0.683438032073173
Zfp791	ENSMUSG00000074194	0.0325051220296006	0.0975153660888017	0.852832278580641	0.852832278580641	0.253294730253595	0.379942095380392
Zfp94	ENSMUSG00000074282	0.393724994268831	0.590587491403246	0.846460676830692	0.846460676830692	0.0153302852334645	0.0459908557003935
Zfp109	ENSMUSG00000074283	0.711445446052875	0.711445446052875	0.576973746230334	0.711445446052875	0.576973746230334	0.711445446052875
Zfp799	ENSMUSG00000095253	0.168646652367079	0.505939957101236	1	1	0.628654363853655	0.942981545780483
Zfp870	ENSMUSG00000095325	0.0953125666339397	0.262038348050444	0.344663224299303	0.344663224299303	0.174692232033629	0.262038348050444

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coral4

Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Zfp81	ENSMUSG00000003929	0.254414773803597	0.446772960955053	0.78180291566155	0.78180291566155	0.297848640636702	0.446772960955053
Apaf1	ENSMUSG00000019979	0.0236697127745139	0.0710091383235417	0.0588232673880149	0.0882349010820223	0.346899083932133	0.346899083932133
Hc	ENSMUSG00000026874	0.0111471670220256	0.0334415010660767	0.710001140920767	0.710001140920767	0.150305279818695	0.225457919728043
Zfp939	ENSMUSG00000030424	0.023800255149993	0.0714007654499789	0.115037265385284	0.172555898077926	0.643359829732651	0.643359829732651
Zfp719	ENSMUSG00000030469	0.557718900865786	0.557718900865786	0.0158546704257247	0.047564011277174	0.23713006400812	0.35569509601218
Zfp944	ENSMUSG00000033972	0.399548817627028	0.578113371816017	0.455625354715449	0.578113371816017	0.578113371816017	0.578113371816017
Ikbke	ENSMUSG00000042349	0.297848640636702	0.57466664340579	0.455625354715449	0.57466664340579	0.57466664340579	0.57466664340579
Zfp866	ENSMUSG00000043090	0.144820068500793	0.21723010275119	1	1	0.0162664168407234	0.0487992505221701
Zfp53	ENSMUSG00000057409	0.0761127945805734	0.22833838374172	0.211844580334808	0.317766870502212	0.709375484777034	0.709375484777034
Zfp933	ENSMUSG00000059423	0.392985378348026	0.589478067522039	0.295581119060361	0.589478067522039	0.853049270252403	0.853049270252403
Zfp772	ENSMUSG00000066838	0.455625354715449	0.683438032073173	0.455625354715449	0.683438032073173	0.926333123228344	0.926333123228344
Zfp760	ENSMUSG00000067928	0.249528554620971	0.748585663862912	0.853801250889739	0.853801250889739	0.643359829732651	0.853801250889739
Zfp808	ENSMUSG00000074867	0.781170242226513	0.781170242226513	0.643359829732651	0.781170242226513	0.255901190956604	0.767703572869812
Gm7221	ENSMUSG00000092335	0.85326530496423	0.85326530496423	0.297472133192261	0.85326530496423	0.85326530496423	0.85326530496423
Gm4944	ENSMUSG00000096433	0.25141795904251	0.377126938563765	0.144820068500793	0.377126938563765	0.709375484777034	0.709375484777034
Zfp953	ENSMUSG00000098905	0.643359829732651	0.853694531487825	0.144820068500793	0.434460205502379	0.853694531487825	0.853694531487825

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cornsilk

Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Zfp40	ENSMUSG00000002617	0.452880492349546	0.679320738524319	0.0117179415987428	0.0351538247962283	0.78180291566155	0.78180291566155
Zfp959	ENSMUSG00000003198	0.926333123228344	0.926333123228344	0.513026869856283	0.769540304784424	0.344663224299303	0.769540304784424
Ikbkg	ENSMUSG00000004221	0.295581119060361	0.392985378348026	0.11810342389482	0.354310271684459	0.392985378348026	0.392985378348026
Srpk1	ENSMUSG00000004865	0.211844580334808	0.317766870502212	0.118409250205154	0.317766870502212	0.643853282854191	0.643853282854191
Zfp790	ENSMUSG00000011427	0.058823267388015	0.176469802164045	0.455625354715449	0.455625354715449	0.256271555563966	0.384407333345949
Zfp715	ENSMUSG00000012640	0.772767153280156	0.92356607045265	0.214037080764326	0.642111242292977	0.92356607045265	0.92356607045265
Ppp1cb	ENSMUSG00000014956	0.254414773803597	0.254414773803597	0.0761127945805735	0.11416919187086	0.0721303428592823	0.11416919187086
Tbk1	ENSMUSG00000020115	0.926441990075769	0.926441990075769	0.144820068500793	0.43446020550238	0.926333123228344	0.926441990075769
Zfp607	ENSMUSG00000020420	0.452880492349546	0.452880492349546	0.0432318933800775	0.129695680140233	0.342405296020881	0.452880492349546
Srsf5	ENSMUSG00000021134	0.0953125666339396	0.142968849950909	0.0164739112492866	0.0494217337478599	0.638824656785692	0.638824656785692
A530054K11Rik	ENSMUSG00000021510	0.146141353215796	0.219212029823694	0.0101222094973346	0.0303666284920038	0.711034989117171	0.711034989117171
Ifnar1	ENSMUSG00000022967	0.45596561163947	0.45596561163947	0.252545530864481	0.378818296296722	0.118409250205154	0.355227750615461
Zfp605	ENSMUSG00000023284	0.00429270217529417	0.0128781065258825	0.0947558980989551	0.142133847148433	0.848872227545608	0.848872227545608
Zfp51	ENSMUSG00000023892	0.120850531362929	0.120850531362929	0.116265430850263	0.120850531362929	0.0969812105731563	0.120850531362929
Eif2ak2	ENSMUSG00000024079	0.393724994268831	0.590587491403246	0.00153425095635555	0.00460275286906664	0.78148726569172	0.78148726569172
Zfp871	ENSMUSG00000024298	0.0766111619812295	0.114916742971844	0.0588232673880149	0.114916742971844	0.148115998140415	0.148115998140415
Jak2	ENSMUSG00000024789	0.216214347033995	0.377126938563765	0.25141795904251	0.377126938563765	0.780851835278818	0.780851835278818
Bad	ENSMUSG00000024959	0.177853449259986	0.266780173889979	0.00199366175750064	0.00598098527250191	0.346527959006435	0.346527959006435
Pou2f1	ENSMUSG00000026565	0.450794830295118	0.450794830295118	0.0726276229843141	0.217882868952942	0.175044824745981	0.262567237118971
Pik3ca	ENSMUSG00000027665	0.148115998140416	0.444347994421247	0.640861491578951	0.711034989117171	0.711034989117171	0.711034989117171
Map3k7	ENSMUSG00000028284	0.214037080764326	0.321055621146489	0.0331400397096515	0.0994201191289545	0.711240436189782	0.711240436189782
Jak1	ENSMUSG00000028530	0.640861491578951	0.640861491578951	0.575536202757516	0.640861491578951	0.140833168780852	0.422499506342555
Pik3r3	ENSMUSG00000028698	0.216214347033995	0.648643041101984	0.78180291566155	0.853694531487825	0.853694531487825	0.853694531487825
Zfp12	ENSMUSG00000029587	0.148115998140415	0.444347994421246	0.346527959006435	0.455625354715449	0.455625354715449	0.455625354715449
Zfp583	ENSMUSG00000030443	0.0100452863122198	0.0301358589366594	0.778747761033626	0.778747761033626	0.0955908182073974	0.143386227311096
Zfp626	ENSMUSG00000030604	0.7048795965722	0.7048795965722	0.0451153644990944	0.135346093497283	0.342026805366747	0.51304020805012
Irak1	ENSMUSG00000031392	0.782117202022501	0.782117202022501	0.255530331334266	0.766590994002797	0.711854160331342	0.782117202022501
Nxf7	ENSMUSG00000031410	0.21549027811633	0.323235417174495	0.00161470887631957	0.0048441266289587	1	1
Tlr3	ENSMUSG00000031639	0.148115998140415	0.222173997210623	0.0721303428592825	0.216391028577848	0.57466664340579	0.57466664340579
Eif2ak3	ENSMUSG00000031668	0.298599969973532	0.599323226440542	0.926658283600152	0.926658283600152	0.399548817627028	0.599323226440542
Tradd	ENSMUSG00000031887	0.146141353215796	0.219212029823693	0.0566379395854603	0.169913818756381	0.641867098978198	0.641867098978198
Birc3	ENSMUSG00000032000	0.710208797518812	0.710208797518812	0.0535981760208404	0.160794528062521	0.452880492349546	0.679320738524319
Zfp7	ENSMUSG00000033669	0.0168921052924602	0.0506763158773805	0.397384062266614	0.596076093399921	0.853694531487825	0.853694531487825
Zfp661	ENSMUSG00000034800	0.0579478375430677	0.142133847148433	0.0947558980989551	0.142133847148433	0.852940894477647	0.852940894477647
Zfp157	ENSMUSG00000036898	0.348008842235184	0.522013263352776	0.0432318933800775	0.129695680140233	0.575824878403157	0.575824878403157
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Zfp60	ENSMUSG00000037640	0.399189600887034	0.51270683838022	0.147787500009832	0.443362500029497	0.51270683838022	0.51270683838022
Ddx58	ENSMUSG00000040296	0.853049270252403	0.853049270252403	0.398829756175299	0.598244634262948	0.252920381501206	0.598244634262948
Zfp764	ENSMUSG00000045757	0.213307944885796	0.23713006400812	0.180293335960318	0.23713006400812	0.23713006400812	0.23713006400812
Zfp84	ENSMUSG00000046185	0.33116978622016	0.398108175780842	0.0716332429957516	0.214899728987255	0.398108175780842	0.398108175780842
Zfp473	ENSMUSG00000048012	0.180293335960318	0.540880007880954	0.643853282854191	0.643853282854191	0.578113371816017	0.643853282854191
Zfp61	ENSMUSG00000050605	0.200650219614881	0.601950658844642	0.777255087907932	0.777255087907932	0.639337105615664	0.777255087907932
Zfp169	ENSMUSG00000050954	0.456305241393103	0.456305241393103	0.00159435459956481	0.00478306379869442	0.300095920620218	0.450143880930327
Zfp11	ENSMUSG00000051034	1	1	0.392614583064079	0.588921874596118	0.119325847749354	0.357977543248062
Zfp455	ENSMUSG00000051037	0.577544706586058	0.926387617028817	0.926387617028817	0.926387617028817	0.853694531487825	0.926387617028817
Zfp961	ENSMUSG00000052446	0.0763619660358786	0.114542949053818	0.124210209545128	0.124210209545128	0.0602750588006477	0.114542949053818
Zfp14	ENSMUSG00000053985	0.34837756124189	0.522566341862834	0.782117202022501	0.782117202022501	0.214764523938594	0.522566341862834
Zfp869	ENSMUSG00000054648	0.248769231421035	0.373153847131552	0.0441715176243983	0.132514552873195	0.511742979522636	0.511742979522636
Zfp182	ENSMUSG00000054737	0.179249687218049	0.268874530827074	0.0164739112492867	0.0494217337478601	0.575824878403157	0.575824878403157
Zfp101	ENSMUSG00000055240	0.392985378348026	0.746437832861452	0.497625221907634	0.746437832861452	0.852832278580641	0.852832278580641
Zfp458	ENSMUSG00000055480	0.513665062682276	0.770497594023414	0.0964252305385472	0.289275691615642	0.926441990075769	0.926441990075769
Zfp1	ENSMUSG00000055835	0.778911768167544	0.851954599472143	0.132758188856147	0.398274566568442	0.851954599472143	0.851954599472143
A430033K04Rik	ENSMUSG00000056014	0.348008842235185	0.522013263352777	0.0761127945805736	0.228338383741721	1	1
AI987944	ENSMUSG00000056383	0.0753654386865988	0.113048158029898	0.00468160475316412	0.0140448142594924	0.509144723230069	0.509144723230069
Zfp658	ENSMUSG00000056592	0.0236697127745138	0.0710091383235414	0.211110344399808	0.211110344399808	0.12085053136293	0.181275797044394
C030039L03Rik	ENSMUSG00000057093	0.576973746230334	0.709375484777034	0.399548817627028	0.709375484777034	0.709375484777034	0.709375484777034
Zfp317	ENSMUSG00000057551	0.248769231421035	0.248769231421035	0.0592616003460512	0.166082403751097	0.110721602500731	0.166082403751097
Zfp595	ENSMUSG00000057842	0.0953125666339396	0.144637845807821	0.0964252305385474	0.144637845807821	0.5155648232968	0.5155648232968
Zfp809	ENSMUSG00000057982	0.101081106532696	0.200650219614881	0.134789313526392	0.200650219614881	0.200650219614881	0.200650219614881
AA987161	ENSMUSG00000058093	0.119631084167592	0.179446626251387	0.0451153644990944	0.135346093497283	0.782117202022501	0.782117202022501
Zfp68	ENSMUSG00000058291	0.297095062262362	0.521459286037555	0.347639524025037	0.521459286037555	0.853372965654504	0.853372965654504
Zfp420	ENSMUSG00000058402	0.576973746230334	0.865460619345501	0.926550375688041	0.926550375688041	0.0880615565264048	0.264184669579214
Zfp958	ENSMUSG00000058748	0.072627622984314	0.217882868952942	0.146800541856249	0.220200812784373	0.853801250889739	0.853801250889739
Rsl1	ENSMUSG00000058900	0.346527959006435	0.519791938509652	0.253294730253594	0.519791938509652	0.782117202022501	0.782117202022501
Zfp426	ENSMUSG00000059475	0.299349060054895	0.643359829732651	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651
Zfp930	ENSMUSG00000059897	0.925444427431699	0.925444427431699	0.0964252305385472	0.264150874616835	0.17610058307789	0.264150874616835
Zfp74	ENSMUSG00000059975	0.5155648232968	0.7733472349452	1	1	0.455625354715449	0.7733472349452
2610008E11Rik	ENSMUSG00000060301	0.642366752097095	0.642366752097095	0.21549027811633	0.642366752097095	0.642366752097095	0.642366752097095
Zfp937	ENSMUSG00000060336	0.119936171404379	0.262038348050444	0.45596561163947	0.45596561163947	0.174692232033629	0.262038348050444
Zfp868	ENSMUSG00000060427	0.711034989117171	0.711034989117171	0.254787123615605	0.711034989117171	0.514934023620345	0.711034989117171
Zfp266	ENSMUSG00000060510	0.338976281569376	0.338976281569376	0.0315593554855452	0.0946780664566356	0.334715083204387	0.338976281569376
Zfp229	ENSMUSG00000061544	0.711034989117171	0.711034989117171	0.455625354715448	0.683438032073173	0.252920381501207	0.683438032073173
Zfp27	ENSMUSG00000062040	0.454942951775341	0.682414427663012	0.0958690133561599	0.28760704006848	0.926003599371282	0.926003599371282
Zfp534	ENSMUSG00000062518	0.0955908182073972	0.286772454622191	0.926387617028817	0.926387617028817	0.778418649115106	0.926387617028817
Zfp398	ENSMUSG00000062519	0.577829325134931	0.577829325134931	0.024062085667391	0.0721862570021729	0.299349060054895	0.449023590082343
Zfp677	ENSMUSG00000062743	0.711240436189781	0.711240436189781	0.299349060054895	0.679320738524319	0.452880492349546	0.679320738524319
Zfp599	ENSMUSG00000062794	0.573498913947369	0.632770400279953	0.0167871584516597	0.0503614753549792	0.632770400279953	0.632770400279953
Zfp563	ENSMUSG00000067424	0.569937449249116	0.569937449249116	0.27173234335943	0.569937449249116	0.508488713161374	0.569937449249116
Zfp763	ENSMUSG00000067430	0.255901190956604	0.767703572869812	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739
Gm13139	ENSMUSG00000067916	0.45596561163947	0.45596561163947	0.0113901882503033	0.0341705647509098	0.290210015182478	0.435315022773717
Zfp442	ENSMUSG00000068130	0.0753654386865988	0.113048158029898	0.058823267388015	0.113048158029898	0.300095920620218	0.300095920620218
Zfp825	ENSMUSG00000069208	0.148115998140416	0.444347994421247	0.778911768167544	0.778911768167544	0.778911768167544	0.778911768167544
1700049G17Rik	ENSMUSG00000070709	0.254414773803597	0.381622160705395	0.236337185850513	0.381622160705395	0.575536202757516	0.575536202757516
Zfp946	ENSMUSG00000071266	0.395928178642446	0.511742979522636	0.00477055016690541	0.0143116505007162	0.511742979522636	0.511742979522636
Zfp58	ENSMUSG00000071291	0.242231702094921	0.363347553142381	0.0300013992894481	0.0900041978683442	0.710416009055326	0.710416009055326
Zfp9	ENSMUSG00000072623	0.214037080764326	0.324321520550992	0.514300775319626	0.514300775319626	0.216214347033995	0.324321520550992
Zfp951	ENSMUSG00000072774	0.171859370212435	0.257789055318653	0.0073134885581712	0.0219404656745136	0.505838378028518	0.505838378028518
Zfp568	ENSMUSG00000074221	0.115651627788148	0.173477441682221	0.926658283600152	0.926658283600152	0.0426702157436794	0.128010647231038
5830428H23Rik	ENSMUSG00000074733	0.0238002551499929	0.0357003827249894	5.62387620362729e-05	0.000168716286108819	0.346527959006435	0.346527959006435
Gm13157	ENSMUSG00000078495	0.255901190956604	0.383851786434905	0.0753654386865988	0.226096316059796	0.576973746230334	0.576973746230334
Gm14391	ENSMUSG00000078903	0.117185073436597	0.351555220309791	0.395928178642446	0.593892267963669	0.78180291566155	0.78180291566155
Zfp111	ENSMUSG00000087598	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.346527959006435	0.926550375688041
Zfp712	ENSMUSG00000090641	0.578113371816017	0.867170057724026	0.0331400397096516	0.0994201191289548	0.926550375688041	0.926550375688041
Gm5141	ENSMUSG00000091183	0.173632433887832	0.520897301663497	0.640861491578951	0.640861491578951	0.575536202757516	0.640861491578951
Zfp964	ENSMUSG00000091764	0.926550375688041	0.926550375688041	0.148115998140416	0.444347994421247	0.853372965654504	0.926550375688041
Zfp141	ENSMUSG00000092416	0.146141353215796	0.438424059647387	0.299349060054895	0.449023590082343	0.7802108304765	0.7802108304765
Gm4767	ENSMUSG00000094076	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282
Gm3055	ENSMUSG00000094622	0.384672302267075	0.384672302267075	0.171859370212435	0.257789055318653	0.0726276229843141	0.217882868952942
Zfp748	ENSMUSG00000095432	0.452880492349546	0.452880492349546	0.0168921052924602	0.0506763158773805	0.334715083204388	0.452880492349546
Gm10778	ENSMUSG00000096856	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282
Zfp82	ENSMUSG00000098022	0.92616891281798	0.926278508226733	0.926278508226733	0.926278508226733	0.215127611919161	0.645382835757484

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Lysine degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Nsd1	ENSMUSG00000021488	0.643359829732651	0.643359829732651	0.298599969973533	0.643359829732651	0.45596561163947	0.643359829732651
Dhtkd1	ENSMUSG00000025815	0.782117202022501	0.782117202022501	0.643853282854191	0.782117202022501	0.643853282854191	0.782117202022501
Ash1l	ENSMUSG00000028053	0.643853282854191	0.643853282854191	0.175044824745981	0.323235417174495	0.21549027811633	0.323235417174495
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Hykk	ENSMUSG00000035878	0.576687400573867	0.853587578053106	0.781645261743309	0.853587578053106	0.853587578053106	0.853587578053106
Setd7	ENSMUSG00000037111	0.454600801949285	0.514300775319626	0.0579478375430678	0.173843512629203	0.514300775319626	0.514300775319626
Kmt2c	ENSMUSG00000038056	0.347639524025037	0.347639524025037	0.345037391052887	0.347639524025037	0.299349060054895	0.347639524025037
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Whsc1l1	ENSMUSG00000054823	0.348008842235184	0.522013263352777	0.180293335960318	0.522013263352777	0.710416009055326	0.710416009055326
Aadat	ENSMUSG00000057228	0.924639851733043	1	0.365324073403582	1	1	1
Suv420h2	ENSMUSG00000059851	0.295581119060361	0.447621891168214	0.447621891168214	0.447621891168214	0.346899083932133	0.447621891168214

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Non-homologous end-joining

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad50	ENSMUSG00000020380	0.575824878403157	0.711650020253571	0.044737329683373	0.134211989050119	0.711650020253571	0.711650020253571
Xrcc6	ENSMUSG00000022471	0.642366752097095	0.963550128145642	0.0969812105731562	0.290943631719469	1	1
Prkdc	ENSMUSG00000022672	0.712057867818062	0.712057867818062	0.514934023620345	0.712057867818062	0.300095920620218	0.712057867818062
Nhej1	ENSMUSG00000026162	0.00153425095635555	0.00460275286906664	0.514300775319626	0.514300775319626	0.392985378348026	0.514300775319626
Dclre1c	ENSMUSG00000026648	0.449391287230099	0.449391287230099	0.0138627169035502	0.0415881507106506	0.161774914569557	0.242662371854336
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Lig4	ENSMUSG00000049717	0.179249687218049	0.522013263352777	0.348008842235184	0.522013263352777	0.577829325134931	0.577829325134931

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mRNA surveillance pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppp1cb	ENSMUSG00000014956	0.254414773803597	0.254414773803597	0.0761127945805735	0.11416919187086	0.0721303428592823	0.11416919187086
Hbs1l	ENSMUSG00000019977	0.148772260628989	0.223158390943483	0.0140567816599278	0.0421703449797833	0.780851835278817	0.780851835278817
Papolg	ENSMUSG00000020273	0.0230207752632622	0.0345311628948933	0.00132605326376098	0.00397815979128293	0.57113445032749	0.57113445032749
Pnn	ENSMUSG00000020994	0.0241933715424143	0.0362900573136214	0.0115535350288052	0.0346606050864156	1	1
Acin1	ENSMUSG00000022185	0.347639524025037	0.521459286037555	0.0969812105731562	0.290943631719469	0.575824878403157	0.575824878403157
Wdr33	ENSMUSG00000024400	0.345410946355104	0.518116419532656	0.058823267388015	0.176469802164045	0.712057867818062	0.712057867818062
Cstf3	ENSMUSG00000027176	0.0447373296833729	0.0671059945250593	0.344663224299303	0.344663224299303	0.00442026986621117	0.0132608095986335
Rngtt	ENSMUSG00000028274	0.115037265385284	0.172555898077926	0.0073134885581712	0.0219404656745136	0.298599969973533	0.298599969973533
Fus	ENSMUSG00000030795	0.643359829732651	0.851732715229127	0.0969812105731562	0.290943631719469	0.851732715229127	0.851732715229127
Cstf2	ENSMUSG00000031256	0.514300775319626	0.771451162979439	0.178901132102685	0.536703396308054	0.78180291566155	0.78180291566155
Nxf7	ENSMUSG00000031410	0.21549027811633	0.323235417174495	0.00161470887631957	0.0048441266289587	1	1
Nudt21	ENSMUSG00000031754	1	1	0.255530331334266	0.766590994002798	0.926550375688041	1
Cpsf7	ENSMUSG00000034820	0.643853282854191	0.711034989117171	0.17610058307789	0.52830174923367	0.711034989117171	0.711034989117171
Pcf11	ENSMUSG00000041328	0.0575107614292585	0.11155406640886	0.0743693776059065	0.11155406640886	0.300095920620218	0.300095920620218
Cpsf2	ENSMUSG00000041781	0.643359829732651	0.643359829732651	0.148115998140416	0.444347994421247	0.638824656785692	0.643359829732651
Nxt2	ENSMUSG00000042271	0.17750354896016	0.26625532344024	0.0321889748775514	0.0965669246326542	0.778911768167544	0.778911768167544
Cpsf6	ENSMUSG00000055531	0.852832278580641	0.852832278580641	0.295581119060361	0.450143880930327	0.300095920620218	0.450143880930327
Gm10094	ENSMUSG00000061104	0.0969812105731562	0.145471815859734	0.00481536616919077	0.0144460985075723	0.348008842235184	0.348008842235184
Wibg	ENSMUSG00000064030	0.0733738589968007	0.220121576990402	0.514934023620345	0.514934023620345	0.454942951775341	0.514934023620345
Dazap1	ENSMUSG00000069565	0.0115535350288052	0.0346606050864156	0.0947558980989551	0.142133847148433	0.398108175780842	0.398108175780842
Msi2	ENSMUSG00000069769	0.297848640636702	0.516994836448954	0.779888212132595	0.779888212132595	0.344663224299303	0.516994836448954

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Amyotrophic lateral sclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Chmp2b	ENSMUSG00000004843	0.567513221841557	0.706831781264721	0.706831781264721	0.706831781264721	0.167929015438905	0.503787046316716
Ndufs3	ENSMUSG00000005510	0.147458757705094	0.221188136557642	0.000125201130991328	0.000375603392973984	0.925444427431699	0.925444427431699
Kif5b	ENSMUSG00000006740	0.0171377151716892	0.0257065727575338	0.00885267753477384	0.0257065727575338	0.563799176258241	0.563799176258241
Hap1	ENSMUSG00000006930	0.853587578053106	0.853587578053106	0.255901190956604	0.767703572869812	0.643112334413352	0.853587578053106
Ndufs2	ENSMUSG00000013593	0.120850531362929	0.181275797044394	0.00130806497567845	0.00392419492703536	0.853372965654504	0.853372965654504
Atp5e	ENSMUSG00000016252	0.0243249029874197	0.0364873544811296	0.0117179415987427	0.0351538247962282	0.782117202022501	0.782117202022501
Gabarap	ENSMUSG00000018567	0.853480389728993	0.853480389728993	0.576112968612194	0.853480389728993	0.708745765211584	0.853480389728993
Atp5g3	ENSMUSG00000018770	0.0331400397096515	0.0497100595644773	0.00283103937188883	0.0084931181156665	0.711854160331342	0.711854160331342
Tbk1	ENSMUSG00000020115	0.926441990075769	0.926441990075769	0.144820068500793	0.43446020550238	0.926333123228344	0.926441990075769
Ndufs7	ENSMUSG00000020153	0.058823267388015	0.0882349010820225	0.00289311433957184	0.00867934301871551	0.642366752097095	0.642366752097095
Uqcr11	ENSMUSG00000020163	0.148115998140416	0.222173997210624	0.0592616003460512	0.177784801038154	0.514934023620345	0.514934023620345
Ndufb9	ENSMUSG00000022354	0.399548817627028	0.452880492349546	0.000164597779190223	0.000493793337570668	0.452880492349546	0.452880492349546
Park2	ENSMUSG00000023826	0.0869438727002336	0.0869438727002336	0.0869438727002335	0.0869438727002336	0.00505279727964405	0.0151583918389322
Dctn4	ENSMUSG00000024603	0.0230207752632622	0.0690623257897866	0.400265374208515	0.400265374208515	0.0575107614292585	0.0862661421438878
Atg2a	ENSMUSG00000024773	0.853801250889739	0.853801250889739	0.044737329683373	0.134211989050119	0.400265374208515	0.600398061312773
Klc2	ENSMUSG00000024862	0.5155648232968	0.850380130396972	0.575536202757516	0.850380130396972	0.850380130396972	0.850380130396972
Bad	ENSMUSG00000024959	0.177853449259986	0.266780173889979	0.00199366175750064	0.00598098527250191	0.346527959006435	0.346527959006435
Psmd1	ENSMUSG00000026229	0.707899741868332	0.707899741868332	0.628654363853655	0.707899741868332	0.0847074989275803	0.254122496782741
Optn	ENSMUSG00000026672	0.78180291566155	0.78180291566155	0.208156293081417	0.62446887924425	0.643359829732651	0.78180291566155
Ndufa8	ENSMUSG00000026895	0.0953125666339396	0.142968849950909	0.00719286546902974	0.0215785964070892	0.710208797518812	0.710208797518812
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Nup210l	ENSMUSG00000027939	0.508817043656046	0.508817043656046	0.399907408151081	0.508817043656046	0.395562602091096	0.508817043656046
Ulk1	ENSMUSG00000029512	0.456305241393103	0.852065168704833	0.709375484777034	0.852065168704833	0.852065168704833	0.852065168704833
Fus	ENSMUSG00000030795	0.643359829732651	0.851732715229127	0.0969812105731562	0.290943631719469	0.851732715229127	0.851732715229127
Ndufab1	ENSMUSG00000030869	0.573498913947369	0.573498913947369	0.000394209637342662	0.00118262891202799	0.450094379653806	0.573498913947369
Nxf7	ENSMUSG00000031410	0.21549027811633	0.323235417174495	0.00161470887631957	0.0048441266289587	1	1
Eif2ak3	ENSMUSG00000031668	0.298599969973532	0.599323226440542	0.926658283600152	0.926658283600152	0.399548817627028	0.599323226440542
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Atxn2l	ENSMUSG00000032637	0.290210015182478	0.435315022773717	0.0328221470541517	0.098466441162455	0.578113371816017	0.578113371816017
Dnah8	ENSMUSG00000033826	0.514934023620345	0.78180291566155	0.78180291566155	0.78180291566155	0.642366752097095	0.78180291566155
Ndufb7	ENSMUSG00000033938	0.0953125666339395	0.285937699901819	0.254414773803597	0.381622160705395	0.853372965654504	0.853372965654504
Ccs	ENSMUSG00000034108	0.0164739112492866	0.02471086687393	0.0164739112492867	0.02471086687393	0.255530331334266	0.255530331334266
Matr3	ENSMUSG00000037236	0.78180291566155	0.78180291566155	0.216214347033995	0.648643041101984	0.513665062682276	0.770497594023414
Ndufv1	ENSMUSG00000037916	0.454600801949285	0.681901202923927	0.179945789077372	0.539837367232115	0.853907737111068	0.853907737111068
Dnah10	ENSMUSG00000038011	0.211110344399808	0.316665516599712	0.0162664168407234	0.0487992505221701	0.926550375688041	0.926550375688041
Uqcrfs1	ENSMUSG00000038462	0.291756209988535	0.437634314982803	5.46967066778588e-05	0.000164090120033576	0.640861491578951	0.640861491578951
Cox6a1	ENSMUSG00000041697	0.711854160331342	0.711854160331342	0.00145633884669441	0.00436901654008323	0.643853282854191	0.711854160331342
Nxt2	ENSMUSG00000042271	0.17750354896016	0.26625532344024	0.0321889748775514	0.0965669246326542	0.778911768167544	0.778911768167544
Setx	ENSMUSG00000043535	0.514300775319626	0.708323672944427	0.708323672944427	0.708323672944427	0.297848640636702	0.708323672944427
Smcr8	ENSMUSG00000049323	0.926658283600152	0.926658283600152	0.400265374208515	0.600398061312773	0.0443599545252853	0.133079863575856
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Dnah3	ENSMUSG00000052273	0.576400475350273	0.853157406788312	0.0430444900328088	0.129133470098426	0.853157406788312	0.853157406788312
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Tank	ENSMUSG00000064289	0.148772260628989	0.223158390943484	0.0681594711637382	0.204478413491214	1	1
mt-Nd5	ENSMUSG00000064367	0.0015541259555958	0.0023311889333937	0.000394209637342661	0.00118262891202798	0.455625354715449	0.455625354715449
mt-Nd4l	ENSMUSG00000065947	0.121155015244363	0.181732522866545	0.0075577836449293	0.0226733509347879	1	1
Map3k5	ENSMUSG00000071369	0.51270683838022	0.703999362653679	0.703999362653679	0.703999362653679	0.508159729612809	0.703999362653679

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Oxidative phosphorylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Ndufs3	ENSMUSG00000005510	0.147458757705094	0.221188136557642	0.000125201130991328	0.000375603392973984	0.925444427431699	0.925444427431699
Atp6v1b2	ENSMUSG00000006273	0.00145633884669442	0.00436901654008325	0.146800541856249	0.220200812784373	0.299349060054895	0.299349060054895
Ndufs2	ENSMUSG00000013593	0.120850531362929	0.181275797044394	0.00130806497567845	0.00392419492703536	0.853372965654504	0.853372965654504
Atp5e	ENSMUSG00000016252	0.0243249029874197	0.0364873544811296	0.0117179415987427	0.0351538247962282	0.782117202022501	0.782117202022501
Atp5g3	ENSMUSG00000018770	0.0331400397096515	0.0497100595644773	0.00283103937188883	0.0084931181156665	0.711854160331342	0.711854160331342
Atp6v0a1	ENSMUSG00000019302	0.213307944885796	0.319961917328694	0.112265881554681	0.319961917328694	0.446194239410717	0.446194239410717
Ndufs7	ENSMUSG00000020153	0.058823267388015	0.0882349010820225	0.00289311433957184	0.00867934301871551	0.642366752097095	0.642366752097095
Uqcr11	ENSMUSG00000020163	0.148115998140416	0.222173997210624	0.0592616003460512	0.177784801038154	0.514934023620345	0.514934023620345
Ndufb9	ENSMUSG00000022354	0.399548817627028	0.452880492349546	0.000164597779190223	0.000493793337570668	0.452880492349546	0.452880492349546
Ndufa8	ENSMUSG00000026895	0.0953125666339396	0.142968849950909	0.00719286546902974	0.0215785964070892	0.710208797518812	0.710208797518812
Ppa2	ENSMUSG00000028013	0.778911768167544	0.778911768167544	0.0138627169035502	0.0415881507106506	0.115037265385284	0.172555898077926
Ndufab1	ENSMUSG00000030869	0.573498913947369	0.573498913947369	0.000394209637342662	0.00118262891202799	0.450094379653806	0.573498913947369
Lhpp	ENSMUSG00000030946	0.0306217702495172	0.0459326553742758	0.0144483832742397	0.043345149822719	0.710001140920767	0.710001140920767
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Atp6v0b	ENSMUSG00000033379	0.0164739112492867	0.02471086687393	0.00477055016690543	0.0143116505007163	0.711034989117171	0.711034989117171
Ndufb7	ENSMUSG00000033938	0.0953125666339395	0.285937699901819	0.254414773803597	0.381622160705395	0.853372965654504	0.853372965654504
Ndufv1	ENSMUSG00000037916	0.454600801949285	0.681901202923927	0.179945789077372	0.539837367232115	0.853907737111068	0.853907737111068
Uqcrfs1	ENSMUSG00000038462	0.291756209988535	0.437634314982803	5.46967066778588e-05	0.000164090120033576	0.640861491578951	0.640861491578951
Cox6a1	ENSMUSG00000041697	0.711854160331342	0.711854160331342	0.00145633884669441	0.00436901654008323	0.643853282854191	0.711854160331342
Atp6v1a	ENSMUSG00000052459	0.513026869856283	0.575824878403157	0.575824878403157	0.575824878403157	0.0969812105731561	0.290943631719468
mt-Nd5	ENSMUSG00000064367	0.0015541259555958	0.0023311889333937	0.000394209637342661	0.00118262891202798	0.455625354715449	0.455625354715449
mt-Nd4l	ENSMUSG00000065947	0.121155015244363	0.181732522866545	0.0075577836449293	0.0226733509347879	1	1

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Thermogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Ndufs3	ENSMUSG00000005510	0.147458757705094	0.221188136557642	0.000125201130991328	0.000375603392973984	0.925444427431699	0.925444427431699
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Ndufs2	ENSMUSG00000013593	0.120850531362929	0.181275797044394	0.00130806497567845	0.00392419492703536	0.853372965654504	0.853372965654504
Atp5e	ENSMUSG00000016252	0.0243249029874197	0.0364873544811296	0.0117179415987427	0.0351538247962282	0.782117202022501	0.782117202022501
Atp5g3	ENSMUSG00000018770	0.0331400397096515	0.0497100595644773	0.00283103937188883	0.0084931181156665	0.711854160331342	0.711854160331342
Ndufs7	ENSMUSG00000020153	0.058823267388015	0.0882349010820225	0.00289311433957184	0.00867934301871551	0.642366752097095	0.642366752097095
Uqcr11	ENSMUSG00000020163	0.148115998140416	0.222173997210624	0.0592616003460512	0.177784801038154	0.514934023620345	0.514934023620345
Frs2	ENSMUSG00000020170	0.638824656785692	0.638824656785692	0.252920381501207	0.521459286037555	0.347639524025037	0.521459286037555
Rps6kb1	ENSMUSG00000020516	0.0761127945805735	0.11416919187086	0.0312459040565944	0.0937377121697832	0.5155648232968	0.5155648232968
Slc25a29	ENSMUSG00000021265	5.62387620362727e-05	0.000168716286108818	0.041737700208629	0.0626065503129434	0.575536202757516	0.575536202757516
Ndufb9	ENSMUSG00000022354	0.399548817627028	0.452880492349546	0.000164597779190223	0.000493793337570668	0.452880492349546	0.452880492349546
Ndufaf7	ENSMUSG00000024082	0.853801250889739	1	1	1	1	1
Rps6kb2	ENSMUSG00000024830	0.577829325134931	0.639337105615664	0.252920381501207	0.639337105615664	0.639337105615664	0.639337105615664
Creb1	ENSMUSG00000025958	0.0168921052924601	0.0506763158773803	0.0441715176243983	0.0662572764365975	0.45596561163947	0.45596561163947
Ndufa8	ENSMUSG00000026895	0.0953125666339396	0.142968849950909	0.00719286546902974	0.0215785964070892	0.710208797518812	0.710208797518812
Ndufaf5	ENSMUSG00000027384	0.0315593554855452	0.0473390332283177	0.00486041086018214	0.0145812325805464	0.513026869856283	0.513026869856283
Rps6	ENSMUSG00000028495	0.509144723230069	0.763717084845103	0.0592616003460512	0.177784801038154	0.78180291566155	0.78180291566155
Ppargc1a	ENSMUSG00000029167	0.148772260628989	0.324321520550992	0.514934023620345	0.514934023620345	0.216214347033994	0.324321520550992
Kras	ENSMUSG00000030265	0.120545895661628	0.180818843492441	0.00768144932639895	0.0230443479791968	0.926658283600152	0.926658283600152
Ndufab1	ENSMUSG00000030869	0.573498913947369	0.573498913947369	0.000394209637342662	0.00118262891202799	0.450094379653806	0.573498913947369
Rps6ka3	ENSMUSG00000031309	0.711854160331342	0.711854160331342	0.0441715176243983	0.132514552873195	0.711034989117171	0.711854160331342
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Ndufb7	ENSMUSG00000033938	0.0953125666339395	0.285937699901819	0.254414773803597	0.381622160705395	0.853372965654504	0.853372965654504
Ndufv1	ENSMUSG00000037916	0.454600801949285	0.681901202923927	0.179945789077372	0.539837367232115	0.853907737111068	0.853907737111068
Uqcrfs1	ENSMUSG00000038462	0.291756209988535	0.437634314982803	5.46967066778588e-05	0.000164090120033576	0.640861491578951	0.640861491578951
Kdm3b	ENSMUSG00000038773	0.576973746230334	0.576973746230334	0.345410946355104	0.576973746230334	0.507830090867449	0.576973746230334
Cox6a1	ENSMUSG00000041697	0.711854160331342	0.711854160331342	0.00145633884669441	0.00436901654008323	0.643853282854191	0.711854160331342
Selrc1	ENSMUSG00000048351	0.643853282854191	0.926333123228344	0.0964252305385472	0.289275691615642	0.926333123228344	0.926333123228344
Kdm3a	ENSMUSG00000053470	0.0103546374915853	0.0310639124747558	0.711240436189781	0.711240436189781	0.511097249598474	0.711240436189781
mt-Nd5	ENSMUSG00000064367	0.0015541259555958	0.0023311889333937	0.000394209637342661	0.00118262891202798	0.455625354715449	0.455625354715449
mt-Nd4l	ENSMUSG00000065947	0.121155015244363	0.181732522866545	0.0075577836449293	0.0226733509347879	1	1
Prkag1	ENSMUSG00000067713	0.00481536616919077	0.00722304925378615	0.000164597779190222	0.000493793337570666	0.711240436189781	0.711240436189781
Map3k5	ENSMUSG00000071369	0.51270683838022	0.703999362653679	0.703999362653679	0.703999362653679	0.508159729612809	0.703999362653679

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Gene expression (Transcription)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Zfp40	ENSMUSG00000002617	0.452880492349546	0.679320738524319	0.0117179415987428	0.0351538247962283	0.78180291566155	0.78180291566155
Baz1b	ENSMUSG00000002748	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739	0.781170242226513	0.853801250889739
Cdk12	ENSMUSG00000003119	0.853694531487825	0.853694531487825	0.0753654386865988	0.226096316059796	0.643359829732651	0.853694531487825
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Hipk1	ENSMUSG00000008730	0.342026805366747	0.513665062682276	0.509144723230069	0.513665062682276	0.513665062682276	0.513665062682276
Zfp790	ENSMUSG00000011427	0.058823267388015	0.176469802164045	0.455625354715449	0.455625354715449	0.256271555563966	0.384407333345949
Tbp	ENSMUSG00000014767	0.179945789077372	0.269918683616058	0.0241933715424143	0.0725801146272428	0.926550375688041	0.926550375688041
Med1	ENSMUSG00000018160	0.643853282854191	0.643853282854191	0.0743693776059064	0.223108132817719	0.347639524025037	0.521459286037555
Smurf2	ENSMUSG00000018363	0.117185073436597	0.175777610154895	0.0936419271039908	0.175777610154895	0.576973746230334	0.576973746230334
Chd3	ENSMUSG00000018474	0.0441715176243982	0.132514552873195	0.297848640636702	0.446772960955053	0.853694531487825	0.853694531487825
Cnot2	ENSMUSG00000020166	0.397384062266614	0.596076093399921	0.0150443553124285	0.0451330659372854	0.92416823462528	0.92416823462528
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Cnot6	ENSMUSG00000020362	0.283930443883615	0.288654423610209	0.0148445652050919	0.0445336956152758	0.288654423610209	0.288654423610209
Slu7	ENSMUSG00000020409	0.0964252305385472	0.144637845807821	0.00463747559282087	0.0139124267784626	0.641867098978197	0.641867098978197
Cnot8	ENSMUSG00000020515	0.17750354896016	0.26625532344024	0.0566379395854602	0.169913818756381	0.57466664340579	0.57466664340579
Twistnb	ENSMUSG00000020561	0.0168921052924601	0.0253381579386902	0.00695468356472022	0.0208640506941607	0.214037080764326	0.214037080764326
Srsf5	ENSMUSG00000021134	0.0953125666339396	0.142968849950909	0.0164739112492866	0.0494217337478599	0.638824656785692	0.638824656785692
Prelid1	ENSMUSG00000021486	0.113498953177704	0.120850531362929	0.120850531362929	0.120850531362929	0.0231661970063528	0.0694985910190584
A530054K11Rik	ENSMUSG00000021510	0.146141353215796	0.219212029823694	0.0101222094973346	0.0303666284920038	0.711034989117171	0.711034989117171
Nr1d2	ENSMUSG00000021775	0.926658283600152	0.926658283600152	0.0964252305385471	0.289275691615641	0.347639524025037	0.521459286037555
Bnip3l	ENSMUSG00000022051	0.0964252305385471	0.144637845807821	0.00943994294581103	0.0283198288374331	0.514300775319626	0.514300775319626
Atad2	ENSMUSG00000022360	0.576973746230334	0.576973746230334	0.0097403746490101	0.0292211239470303	0.342405296020881	0.513607944031322
Zfp263	ENSMUSG00000022529	0.515249728559994	0.642117186565222	0.096147151118103	0.288441453354309	0.642117186565222	0.642117186565222
Nr4a1	ENSMUSG00000023034	0.513026869856283	0.513026869856283	0.180293335960318	0.270440003940477	0.178901132102685	0.270440003940477
Zfp51	ENSMUSG00000023892	0.120850531362929	0.120850531362929	0.116265430850263	0.120850531362929	0.0969812105731563	0.120850531362929
Pdpk1	ENSMUSG00000024122	0.288654423610209	0.288654423610209	0.0334587898203824	0.100376369461147	0.091411676944639	0.137117515416958
Epc1	ENSMUSG00000024240	0.0969812105731562	0.145471815859734	0.0441715176243983	0.132514552873195	0.711854160331342	0.711854160331342
Zfp871	ENSMUSG00000024298	0.0766111619812295	0.114916742971844	0.0588232673880149	0.114916742971844	0.148115998140415	0.148115998140415
Iws1	ENSMUSG00000024384	0.146800541856249	0.220200812784373	0.0164739112492867	0.0494217337478602	0.249907451332337	0.249907451332337
Wdr33	ENSMUSG00000024400	0.345410946355104	0.518116419532656	0.058823267388015	0.176469802164045	0.712057867818062	0.712057867818062
Lrdd	ENSMUSG00000025507	0.853480389728993	0.853480389728993	0.254414773803597	0.763244321410791	0.853372965654504	0.853480389728993
Nabp1	ENSMUSG00000026107	0.851061028660105	0.851061028660105	0.00472596298562397	0.0141778889568719	0.779726369441083	0.851061028660105
Psmd1	ENSMUSG00000026229	0.707899741868332	0.707899741868332	0.628654363853655	0.707899741868332	0.0847074989275803	0.254122496782741
Ccnt2	ENSMUSG00000026349	0.246861959455465	0.246861959455465	0.0334587898203823	0.100376369461147	0.243396309647536	0.246861959455465
Rbbp5	ENSMUSG00000026439	0.926333123228344	0.926333123228344	0.179945789077372	0.269918683616058	0.0553321944628786	0.165996583388636
Pou2f1	ENSMUSG00000026565	0.450794830295118	0.450794830295118	0.0726276229843141	0.217882868952942	0.175044824745981	0.262567237118971
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Ttf1	ENSMUSG00000026803	0.300095920620218	0.300095920620218	0.00719286546902974	0.0215785964070892	0.0432318933800775	0.0648478400701162
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Cstf3	ENSMUSG00000027176	0.0447373296833729	0.0671059945250593	0.344663224299303	0.344663224299303	0.00442026986621117	0.0132608095986335
Zc3h8	ENSMUSG00000027387	0.782117202022501	0.926333123228344	0.711854160331342	0.926333123228344	0.926333123228344	0.926333123228344
Tpx2	ENSMUSG00000027469	0.642366752097095	0.926333123228344	0.0592616003460512	0.177784801038154	0.926333123228344	0.926333123228344
Itch	ENSMUSG00000027598	0.455625354715449	0.455625354715449	0.348008842235184	0.455625354715449	0.454600801949284	0.455625354715449
Trp53inp1	ENSMUSG00000028211	0.147458757705095	0.268351698154027	0.782117202022501	0.782117202022501	0.178901132102685	0.268351698154027
Ccne2	ENSMUSG00000028212	0.180293335960318	0.270440003940478	0.0451153644990945	0.135346093497283	0.7802108304765	0.7802108304765
Nbn	ENSMUSG00000028224	0.216214347033994	0.324321520550991	0.0426702157436794	0.128010647231038	0.853801250889739	0.853801250889739
Ccnc	ENSMUSG00000028252	0.453570536021945	0.680355804032917	0.711034989117171	0.711034989117171	0.399548817627028	0.680355804032917
Rngtt	ENSMUSG00000028274	0.115037265385284	0.172555898077926	0.0073134885581712	0.0219404656745136	0.298599969973533	0.298599969973533
Snapc3	ENSMUSG00000028483	0.171859370212435	0.205174703261494	0.0164739112492867	0.0494217337478602	0.205174703261494	0.205174703261494
Ago3	ENSMUSG00000028842	0.400265374208515	0.600398061312773	0.640861491578951	0.640861491578951	0.398108175780842	0.600398061312773
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Trp73	ENSMUSG00000029026	0.631140429608896	0.631140429608896	0.336273664439462	0.631140429608896	0.441110460794563	0.631140429608896
Polr2b	ENSMUSG00000029250	0.348008842235184	0.348008842235184	0.348008842235184	0.348008842235184	0.148115998140416	0.348008842235184
Mtf2	ENSMUSG00000029267	0.853049270252403	0.853049270252403	0.0936419271039908	0.280925781311972	0.254414773803597	0.381622160705395
Gtf2h3	ENSMUSG00000029387	0.562539849036184	0.563799176258241	0.450444934184774	0.563799176258241	0.563799176258241	0.563799176258241
Zfp12	ENSMUSG00000029587	0.148115998140415	0.444347994421246	0.346527959006435	0.455625354715449	0.455625354715449	0.455625354715449
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Kras	ENSMUSG00000030265	0.120545895661628	0.180818843492441	0.00768144932639895	0.0230443479791968	0.926658283600152	0.926658283600152
Zfp606	ENSMUSG00000030386	0.513665062682276	0.711854160331342	0.711854160331342	0.711854160331342	0.514934023620345	0.711854160331342
Zfp583	ENSMUSG00000030443	0.0100452863122198	0.0301358589366594	0.778747761033626	0.778747761033626	0.0955908182073974	0.143386227311096
Zfp626	ENSMUSG00000030604	0.7048795965722	0.7048795965722	0.0451153644990944	0.135346093497283	0.342026805366747	0.51304020805012
Tead2	ENSMUSG00000030796	1	1	0.300095920620217	0.900287761860652	0.782117202022501	1
Cstf2	ENSMUSG00000031256	0.514300775319626	0.771451162979439	0.178901132102685	0.536703396308054	0.78180291566155	0.78180291566155
Wrn	ENSMUSG00000031583	0.92589277149125	0.92589277149125	0.004463251977831	0.013389755933493	0.023800255149993	0.0357003827249895
Nudt21	ENSMUSG00000031754	1	1	0.255530331334266	0.766590994002798	0.926550375688041	1
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Ints10	ENSMUSG00000031864	0.249907451332337	0.374861176998506	0.572616808177226	0.572616808177226	0.179249687218049	0.374861176998506
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Chek1	ENSMUSG00000032113	0.9255572759333	0.9255572759333	0.451840588205062	0.9255572759333	0.777255087907932	0.9255572759333
Rnf111	ENSMUSG00000032217	0.343537039781257	0.450444934184774	0.399548817627028	0.450444934184774	0.450444934184774	0.450444934184774
Arid2	ENSMUSG00000033237	0.395562602091096	0.852723421673413	0.711854160331342	0.852723421673413	0.852723421673413	0.852723421673413
Gtf2a2	ENSMUSG00000033543	0.782117202022501	0.926333123228344	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344
Mga	ENSMUSG00000033943	0.250285839267991	0.250285839267991	0.0953125666339397	0.250285839267991	0.211110344399808	0.250285839267991
Med13	ENSMUSG00000034297	0.120545895661627	0.180818843492441	0.00159435459956481	0.00478306379869444	0.926003599371282	0.926003599371282
Cnot6l	ENSMUSG00000034724	0.398108175780842	0.398108175780842	0.0230207752632622	0.0345311628948933	0.016682476544732	0.0345311628948933
Zfp661	ENSMUSG00000034800	0.0579478375430677	0.142133847148433	0.0947558980989551	0.142133847148433	0.852940894477647	0.852940894477647
Cpsf7	ENSMUSG00000034820	0.643853282854191	0.711034989117171	0.17610058307789	0.52830174923367	0.711034989117171	0.711034989117171
Ints6	ENSMUSG00000035161	0.144820068500793	0.381622160705395	0.254414773803597	0.381622160705395	0.712057867818062	0.712057867818062
Mbd3	ENSMUSG00000035478	0.00743512899358789	0.011336675467394	0.0075577836449293	0.011336675467394	1	1
Zfp157	ENSMUSG00000036898	0.348008842235184	0.522013263352776	0.0432318933800775	0.129695680140233	0.575824878403157	0.575824878403157
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Thoc2	ENSMUSG00000037475	0.121155015244363	0.181732522866544	0.0168921052924602	0.0506763158773805	0.249528554620971	0.249528554620971
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Cdc40	ENSMUSG00000038446	0.0766111619812295	0.114916742971844	0.000157492167861666	0.000472476503584999	0.705968934865368	0.705968934865368
Smurf1	ENSMUSG00000038780	0.298599969973533	0.447899954960299	0.0579478375430677	0.173843512629203	0.926550375688041	0.926550375688041
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
H2afv	ENSMUSG00000041126	0.0115535350288052	0.0173303025432078	0.00477055016690543	0.0143116505007163	0.45596561163947	0.45596561163947
Cdk13	ENSMUSG00000041297	0.450094379653806	0.570836132666921	0.115651627788147	0.346954883364442	0.570836132666921	0.570836132666921
Gtf3c3	ENSMUSG00000041303	0.578113371816017	0.78148726569172	0.0171027900598199	0.0513083701794598	0.78148726569172	0.78148726569172
Pcf11	ENSMUSG00000041328	0.0575107614292585	0.11155406640886	0.0743693776059065	0.11155406640886	0.300095920620218	0.300095920620218
Cpsf2	ENSMUSG00000041781	0.643359829732651	0.643359829732651	0.148115998140416	0.444347994421247	0.638824656785692	0.643359829732651
Pbrm1	ENSMUSG00000042323	0.511742979522636	0.511742979522636	0.0575107614292585	0.172532284287776	0.400265374208515	0.511742979522636
Gatad2b	ENSMUSG00000042390	0.455625354715448	0.455625354715448	0.346527959006435	0.455625354715448	0.255901190956604	0.455625354715448
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Zfp445	ENSMUSG00000047036	0.171859370212435	0.171859370212435	0.0419238354397912	0.125771506319374	0.138156294413154	0.171859370212435
Slc38a9	ENSMUSG00000047789	0.300095920620218	0.450143880930327	0.298599969973533	0.450143880930327	0.578113371816017	0.578113371816017
Tnrc6b	ENSMUSG00000047888	0.643359829732651	0.643359829732651	0.5155648232968	0.643359829732651	0.179945789077372	0.539837367232116
Zfp473	ENSMUSG00000048012	0.180293335960318	0.540880007880954	0.643853282854191	0.643853282854191	0.578113371816017	0.643853282854191
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Zfp738	ENSMUSG00000048280	0.0171027900598199	0.0360931285010865	0.024062085667391	0.0360931285010865	0.345410946355104	0.345410946355104
Aff4	ENSMUSG00000049470	0.0880615565264046	0.132092334789607	0.0523032931247597	0.132092334789607	0.513665062682276	0.513665062682276
Bdp1	ENSMUSG00000049658	0.00153425095635554	0.00230137643453331	0.000157492167861667	0.000472476503585001	0.148115998140416	0.148115998140416
Rictor	ENSMUSG00000050310	0.21549027811633	0.21549027811633	0.0592616003460512	0.177784801038154	0.146141353215796	0.21549027811633
Zfp61	ENSMUSG00000050605	0.200650219614881	0.601950658844642	0.777255087907932	0.777255087907932	0.639337105615664	0.777255087907932
Zfp169	ENSMUSG00000050954	0.456305241393103	0.456305241393103	0.00159435459956481	0.00478306379869442	0.300095920620218	0.450143880930327
Zfp11	ENSMUSG00000051034	1	1	0.392614583064079	0.588921874596118	0.119325847749354	0.357977543248062
Zfp455	ENSMUSG00000051037	0.577544706586058	0.926387617028817	0.926387617028817	0.926387617028817	0.853694531487825	0.926387617028817
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Zfp961	ENSMUSG00000052446	0.0763619660358786	0.114542949053818	0.124210209545128	0.124210209545128	0.0602750588006477	0.114542949053818
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Zfp14	ENSMUSG00000053985	0.34837756124189	0.522566341862834	0.782117202022501	0.782117202022501	0.214764523938594	0.522566341862834
Ercc6	ENSMUSG00000054051	0.21549027811633	0.346527959006435	0.255901190956604	0.346527959006435	0.346527959006435	0.346527959006435
Mdm4	ENSMUSG00000054387	0.0436072256433733	0.0654108384650599	0.0113089139751576	0.0339267419254727	0.346899083932133	0.346899083932133
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Zfp101	ENSMUSG00000055240	0.392985378348026	0.746437832861452	0.497625221907634	0.746437832861452	0.852832278580641	0.852832278580641
Zfp458	ENSMUSG00000055480	0.513665062682276	0.770497594023414	0.0964252305385472	0.289275691615642	0.926441990075769	0.926441990075769
A430033K04Rik	ENSMUSG00000056014	0.348008842235185	0.522013263352777	0.0761127945805736	0.228338383741721	1	1
AI987944	ENSMUSG00000056383	0.0753654386865988	0.113048158029898	0.00468160475316412	0.0140448142594924	0.509144723230069	0.509144723230069
Zfp658	ENSMUSG00000056592	0.0236697127745138	0.0710091383235414	0.211110344399808	0.211110344399808	0.12085053136293	0.181275797044394
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
Zfp317	ENSMUSG00000057551	0.248769231421035	0.248769231421035	0.0592616003460512	0.166082403751097	0.110721602500731	0.166082403751097
Zfp595	ENSMUSG00000057842	0.0953125666339396	0.144637845807821	0.0964252305385474	0.144637845807821	0.5155648232968	0.5155648232968
Zfp420	ENSMUSG00000058402	0.576973746230334	0.865460619345501	0.926550375688041	0.926550375688041	0.0880615565264048	0.264184669579214
Rsl1	ENSMUSG00000058900	0.346527959006435	0.519791938509652	0.253294730253594	0.519791938509652	0.782117202022501	0.782117202022501
Zfp426	ENSMUSG00000059475	0.299349060054895	0.643359829732651	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651
Zfp74	ENSMUSG00000059975	0.5155648232968	0.7733472349452	1	1	0.455625354715449	0.7733472349452
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Zfp937	ENSMUSG00000060336	0.119936171404379	0.262038348050444	0.45596561163947	0.45596561163947	0.174692232033629	0.262038348050444
Zfp229	ENSMUSG00000061544	0.711034989117171	0.711034989117171	0.455625354715448	0.683438032073173	0.252920381501207	0.683438032073173
Zfp27	ENSMUSG00000062040	0.454942951775341	0.682414427663012	0.0958690133561599	0.28760704006848	0.926003599371282	0.926003599371282
Zfp398	ENSMUSG00000062519	0.577829325134931	0.577829325134931	0.024062085667391	0.0721862570021729	0.299349060054895	0.449023590082343
Zfp677	ENSMUSG00000062743	0.711240436189781	0.711240436189781	0.299349060054895	0.679320738524319	0.452880492349546	0.679320738524319
Zkscan8	ENSMUSG00000063894	0.514934023620344	0.514934023620344	0.178901132102684	0.514934023620344	0.346527959006435	0.514934023620344
Nupl1	ENSMUSG00000063895	0.105759219123975	0.158638828685963	0.00644160009194374	0.0193248002758312	0.194519294776045	0.194519294776045
Med14	ENSMUSG00000064127	0.0523032931247596	0.0784549396871394	0.014844565205092	0.044533695615276	0.78180291566155	0.78180291566155
Cenpj	ENSMUSG00000064128	0.179597906187076	0.269396859280614	0.17855224077719	0.269396859280614	0.6976092207787	0.6976092207787
Zfp932	ENSMUSG00000066613	0.236337185850513	0.341647690705446	0.249907451332337	0.341647690705446	0.341647690705446	0.341647690705446
Zfp563	ENSMUSG00000067424	0.569937449249116	0.569937449249116	0.27173234335943	0.569937449249116	0.508488713161374	0.569937449249116
Zfp763	ENSMUSG00000067430	0.255901190956604	0.767703572869812	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739
Prkag1	ENSMUSG00000067713	0.00481536616919077	0.00722304925378615	0.000164597779190222	0.000493793337570666	0.711240436189781	0.711240436189781
Zfp442	ENSMUSG00000068130	0.0753654386865988	0.113048158029898	0.058823267388015	0.113048158029898	0.300095920620218	0.300095920620218
1700049G17Rik	ENSMUSG00000070709	0.254414773803597	0.381622160705395	0.236337185850513	0.381622160705395	0.575536202757516	0.575536202757516
Cited4	ENSMUSG00000070803	0.147458757705094	0.148772260628989	0.0164739112492867	0.0494217337478601	0.148772260628989	0.148772260628989
Zfp942	ENSMUSG00000071267	0.180293335960318	0.324321520550992	0.216214347033994	0.324321520550992	0.576973746230334	0.576973746230334
Taf1a	ENSMUSG00000072258	0.254414773803596	0.381622160705395	0.0112279066750831	0.0336837200252494	0.575246939700399	0.575246939700399
Zfp9	ENSMUSG00000072623	0.214037080764326	0.324321520550992	0.514300775319626	0.514300775319626	0.216214347033995	0.324321520550992
Etohi1	ENSMUSG00000074519	0.0171027900598199	0.0256541850897299	0.000373355180054072	0.00112006554016222	0.511742979522636	0.511742979522636
5830428H23Rik	ENSMUSG00000074733	0.0238002551499929	0.0357003827249894	5.62387620362729e-05	0.000168716286108819	0.346527959006435	0.346527959006435
Rslcan18	ENSMUSG00000074824	0.000387171985540247	0.00116151595662074	0.255901190956604	0.346899083932133	0.346899083932133	0.346899083932133
Ywhaq	ENSMUSG00000076432	0.342026805366747	0.853372965654504	0.853372965654504	0.853372965654504	0.576973746230334	0.853372965654504
Gm14420	ENSMUSG00000078866	0.000795094181770697	0.00238528254531209	0.058823267388015	0.0882349010820225	0.926550375688041	0.926550375688041
Gm14391	ENSMUSG00000078903	0.117185073436597	0.351555220309791	0.395928178642446	0.593892267963669	0.78180291566155	0.78180291566155
Med12	ENSMUSG00000079487	0.197598874030478	0.377126938563765	0.25141795904251	0.377126938563765	1	1
Zfp111	ENSMUSG00000087598	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.346527959006435	0.926550375688041
Zfp882	ENSMUSG00000089857	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028	0.144820068500793	0.21723010275119
Gm14399	ENSMUSG00000090093	5.46967066778586e-05	0.000164090120033576	0.0449262652924809	0.0673893979387214	0.643359829732651	0.643359829732651
Gm5141	ENSMUSG00000091183	0.173632433887832	0.520897301663497	0.640861491578951	0.640861491578951	0.575536202757516	0.640861491578951
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
Zfp964	ENSMUSG00000091764	0.926550375688041	0.926550375688041	0.148115998140416	0.444347994421247	0.853372965654504	0.926550375688041
Sco2	ENSMUSG00000091780	0.513665062682276	0.573498913947369	0.0168921052924602	0.0506763158773805	0.573498913947369	0.573498913947369
Gm4767	ENSMUSG00000094076	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282
Zfp748	ENSMUSG00000095432	0.452880492349546	0.452880492349546	0.0168921052924602	0.0506763158773805	0.334715083204388	0.452880492349546
Gm10778	ENSMUSG00000096856	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282

Download data as csv

RNA Polymerase II Transcription

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Zfp40	ENSMUSG00000002617	0.452880492349546	0.679320738524319	0.0117179415987428	0.0351538247962283	0.78180291566155	0.78180291566155
Cdk12	ENSMUSG00000003119	0.853694531487825	0.853694531487825	0.0753654386865988	0.226096316059796	0.643359829732651	0.853694531487825
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Hipk1	ENSMUSG00000008730	0.342026805366747	0.513665062682276	0.509144723230069	0.513665062682276	0.513665062682276	0.513665062682276
Zfp790	ENSMUSG00000011427	0.058823267388015	0.176469802164045	0.455625354715449	0.455625354715449	0.256271555563966	0.384407333345949
Tbp	ENSMUSG00000014767	0.179945789077372	0.269918683616058	0.0241933715424143	0.0725801146272428	0.926550375688041	0.926550375688041
Med1	ENSMUSG00000018160	0.643853282854191	0.643853282854191	0.0743693776059064	0.223108132817719	0.347639524025037	0.521459286037555
Smurf2	ENSMUSG00000018363	0.117185073436597	0.175777610154895	0.0936419271039908	0.175777610154895	0.576973746230334	0.576973746230334
Chd3	ENSMUSG00000018474	0.0441715176243982	0.132514552873195	0.297848640636702	0.446772960955053	0.853694531487825	0.853694531487825
Cnot2	ENSMUSG00000020166	0.397384062266614	0.596076093399921	0.0150443553124285	0.0451330659372854	0.92416823462528	0.92416823462528
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Cnot6	ENSMUSG00000020362	0.283930443883615	0.288654423610209	0.0148445652050919	0.0445336956152758	0.288654423610209	0.288654423610209
Slu7	ENSMUSG00000020409	0.0964252305385472	0.144637845807821	0.00463747559282087	0.0139124267784626	0.641867098978197	0.641867098978197
Cnot8	ENSMUSG00000020515	0.17750354896016	0.26625532344024	0.0566379395854602	0.169913818756381	0.57466664340579	0.57466664340579
Srsf5	ENSMUSG00000021134	0.0953125666339396	0.142968849950909	0.0164739112492866	0.0494217337478599	0.638824656785692	0.638824656785692
Prelid1	ENSMUSG00000021486	0.113498953177704	0.120850531362929	0.120850531362929	0.120850531362929	0.0231661970063528	0.0694985910190584
A530054K11Rik	ENSMUSG00000021510	0.146141353215796	0.219212029823694	0.0101222094973346	0.0303666284920038	0.711034989117171	0.711034989117171
Nr1d2	ENSMUSG00000021775	0.926658283600152	0.926658283600152	0.0964252305385471	0.289275691615641	0.347639524025037	0.521459286037555
Bnip3l	ENSMUSG00000022051	0.0964252305385471	0.144637845807821	0.00943994294581103	0.0283198288374331	0.514300775319626	0.514300775319626
Atad2	ENSMUSG00000022360	0.576973746230334	0.576973746230334	0.0097403746490101	0.0292211239470303	0.342405296020881	0.513607944031322
Zfp263	ENSMUSG00000022529	0.515249728559994	0.642117186565222	0.096147151118103	0.288441453354309	0.642117186565222	0.642117186565222
Nr4a1	ENSMUSG00000023034	0.513026869856283	0.513026869856283	0.180293335960318	0.270440003940477	0.178901132102685	0.270440003940477
Zfp51	ENSMUSG00000023892	0.120850531362929	0.120850531362929	0.116265430850263	0.120850531362929	0.0969812105731563	0.120850531362929
Pdpk1	ENSMUSG00000024122	0.288654423610209	0.288654423610209	0.0334587898203824	0.100376369461147	0.091411676944639	0.137117515416958
Epc1	ENSMUSG00000024240	0.0969812105731562	0.145471815859734	0.0441715176243983	0.132514552873195	0.711854160331342	0.711854160331342
Zfp871	ENSMUSG00000024298	0.0766111619812295	0.114916742971844	0.0588232673880149	0.114916742971844	0.148115998140415	0.148115998140415
Iws1	ENSMUSG00000024384	0.146800541856249	0.220200812784373	0.0164739112492867	0.0494217337478602	0.249907451332337	0.249907451332337
Wdr33	ENSMUSG00000024400	0.345410946355104	0.518116419532656	0.058823267388015	0.176469802164045	0.712057867818062	0.712057867818062
Lrdd	ENSMUSG00000025507	0.853480389728993	0.853480389728993	0.254414773803597	0.763244321410791	0.853372965654504	0.853480389728993
Nabp1	ENSMUSG00000026107	0.851061028660105	0.851061028660105	0.00472596298562397	0.0141778889568719	0.779726369441083	0.851061028660105
Psmd1	ENSMUSG00000026229	0.707899741868332	0.707899741868332	0.628654363853655	0.707899741868332	0.0847074989275803	0.254122496782741
Ccnt2	ENSMUSG00000026349	0.246861959455465	0.246861959455465	0.0334587898203823	0.100376369461147	0.243396309647536	0.246861959455465
Rbbp5	ENSMUSG00000026439	0.926333123228344	0.926333123228344	0.179945789077372	0.269918683616058	0.0553321944628786	0.165996583388636
Pou2f1	ENSMUSG00000026565	0.450794830295118	0.450794830295118	0.0726276229843141	0.217882868952942	0.175044824745981	0.262567237118971
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Cstf3	ENSMUSG00000027176	0.0447373296833729	0.0671059945250593	0.344663224299303	0.344663224299303	0.00442026986621117	0.0132608095986335
Zc3h8	ENSMUSG00000027387	0.782117202022501	0.926333123228344	0.711854160331342	0.926333123228344	0.926333123228344	0.926333123228344
Tpx2	ENSMUSG00000027469	0.642366752097095	0.926333123228344	0.0592616003460512	0.177784801038154	0.926333123228344	0.926333123228344
Itch	ENSMUSG00000027598	0.455625354715449	0.455625354715449	0.348008842235184	0.455625354715449	0.454600801949284	0.455625354715449
Trp53inp1	ENSMUSG00000028211	0.147458757705095	0.268351698154027	0.782117202022501	0.782117202022501	0.178901132102685	0.268351698154027
Ccne2	ENSMUSG00000028212	0.180293335960318	0.270440003940478	0.0451153644990945	0.135346093497283	0.7802108304765	0.7802108304765
Nbn	ENSMUSG00000028224	0.216214347033994	0.324321520550991	0.0426702157436794	0.128010647231038	0.853801250889739	0.853801250889739
Ccnc	ENSMUSG00000028252	0.453570536021945	0.680355804032917	0.711034989117171	0.711034989117171	0.399548817627028	0.680355804032917
Rngtt	ENSMUSG00000028274	0.115037265385284	0.172555898077926	0.0073134885581712	0.0219404656745136	0.298599969973533	0.298599969973533
Snapc3	ENSMUSG00000028483	0.171859370212435	0.205174703261494	0.0164739112492867	0.0494217337478602	0.205174703261494	0.205174703261494
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Trp73	ENSMUSG00000029026	0.631140429608896	0.631140429608896	0.336273664439462	0.631140429608896	0.441110460794563	0.631140429608896
Polr2b	ENSMUSG00000029250	0.348008842235184	0.348008842235184	0.348008842235184	0.348008842235184	0.148115998140416	0.348008842235184
Gtf2h3	ENSMUSG00000029387	0.562539849036184	0.563799176258241	0.450444934184774	0.563799176258241	0.563799176258241	0.563799176258241
Zfp12	ENSMUSG00000029587	0.148115998140415	0.444347994421246	0.346527959006435	0.455625354715449	0.455625354715449	0.455625354715449
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Kras	ENSMUSG00000030265	0.120545895661628	0.180818843492441	0.00768144932639895	0.0230443479791968	0.926658283600152	0.926658283600152
Zfp606	ENSMUSG00000030386	0.513665062682276	0.711854160331342	0.711854160331342	0.711854160331342	0.514934023620345	0.711854160331342
Zfp583	ENSMUSG00000030443	0.0100452863122198	0.0301358589366594	0.778747761033626	0.778747761033626	0.0955908182073974	0.143386227311096
Zfp626	ENSMUSG00000030604	0.7048795965722	0.7048795965722	0.0451153644990944	0.135346093497283	0.342026805366747	0.51304020805012
Tead2	ENSMUSG00000030796	1	1	0.300095920620217	0.900287761860652	0.782117202022501	1
Cstf2	ENSMUSG00000031256	0.514300775319626	0.771451162979439	0.178901132102685	0.536703396308054	0.78180291566155	0.78180291566155
Wrn	ENSMUSG00000031583	0.92589277149125	0.92589277149125	0.004463251977831	0.013389755933493	0.023800255149993	0.0357003827249895
Nudt21	ENSMUSG00000031754	1	1	0.255530331334266	0.766590994002798	0.926550375688041	1
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Ints10	ENSMUSG00000031864	0.249907451332337	0.374861176998506	0.572616808177226	0.572616808177226	0.179249687218049	0.374861176998506
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Chek1	ENSMUSG00000032113	0.9255572759333	0.9255572759333	0.451840588205062	0.9255572759333	0.777255087907932	0.9255572759333
Rnf111	ENSMUSG00000032217	0.343537039781257	0.450444934184774	0.399548817627028	0.450444934184774	0.450444934184774	0.450444934184774
Arid2	ENSMUSG00000033237	0.395562602091096	0.852723421673413	0.711854160331342	0.852723421673413	0.852723421673413	0.852723421673413
Gtf2a2	ENSMUSG00000033543	0.782117202022501	0.926333123228344	0.641867098978198	0.926333123228344	0.926333123228344	0.926333123228344
Mga	ENSMUSG00000033943	0.250285839267991	0.250285839267991	0.0953125666339397	0.250285839267991	0.211110344399808	0.250285839267991
Med13	ENSMUSG00000034297	0.120545895661627	0.180818843492441	0.00159435459956481	0.00478306379869444	0.926003599371282	0.926003599371282
Cnot6l	ENSMUSG00000034724	0.398108175780842	0.398108175780842	0.0230207752632622	0.0345311628948933	0.016682476544732	0.0345311628948933
Zfp661	ENSMUSG00000034800	0.0579478375430677	0.142133847148433	0.0947558980989551	0.142133847148433	0.852940894477647	0.852940894477647
Cpsf7	ENSMUSG00000034820	0.643853282854191	0.711034989117171	0.17610058307789	0.52830174923367	0.711034989117171	0.711034989117171
Ints6	ENSMUSG00000035161	0.144820068500793	0.381622160705395	0.254414773803597	0.381622160705395	0.712057867818062	0.712057867818062
Mbd3	ENSMUSG00000035478	0.00743512899358789	0.011336675467394	0.0075577836449293	0.011336675467394	1	1
Zfp157	ENSMUSG00000036898	0.348008842235184	0.522013263352776	0.0432318933800775	0.129695680140233	0.575824878403157	0.575824878403157
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Thoc2	ENSMUSG00000037475	0.121155015244363	0.181732522866544	0.0168921052924602	0.0506763158773805	0.249528554620971	0.249528554620971
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Cdc40	ENSMUSG00000038446	0.0766111619812295	0.114916742971844	0.000157492167861666	0.000472476503584999	0.705968934865368	0.705968934865368
Smurf1	ENSMUSG00000038780	0.298599969973533	0.447899954960299	0.0579478375430677	0.173843512629203	0.926550375688041	0.926550375688041
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
H2afv	ENSMUSG00000041126	0.0115535350288052	0.0173303025432078	0.00477055016690543	0.0143116505007163	0.45596561163947	0.45596561163947
Cdk13	ENSMUSG00000041297	0.450094379653806	0.570836132666921	0.115651627788147	0.346954883364442	0.570836132666921	0.570836132666921
Pcf11	ENSMUSG00000041328	0.0575107614292585	0.11155406640886	0.0743693776059065	0.11155406640886	0.300095920620218	0.300095920620218
Cpsf2	ENSMUSG00000041781	0.643359829732651	0.643359829732651	0.148115998140416	0.444347994421247	0.638824656785692	0.643359829732651
Pbrm1	ENSMUSG00000042323	0.511742979522636	0.511742979522636	0.0575107614292585	0.172532284287776	0.400265374208515	0.511742979522636
Gatad2b	ENSMUSG00000042390	0.455625354715448	0.455625354715448	0.346527959006435	0.455625354715448	0.255901190956604	0.455625354715448
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Zfp445	ENSMUSG00000047036	0.171859370212435	0.171859370212435	0.0419238354397912	0.125771506319374	0.138156294413154	0.171859370212435
Slc38a9	ENSMUSG00000047789	0.300095920620218	0.450143880930327	0.298599969973533	0.450143880930327	0.578113371816017	0.578113371816017
Zfp473	ENSMUSG00000048012	0.180293335960318	0.540880007880954	0.643853282854191	0.643853282854191	0.578113371816017	0.643853282854191
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Zfp738	ENSMUSG00000048280	0.0171027900598199	0.0360931285010865	0.024062085667391	0.0360931285010865	0.345410946355104	0.345410946355104
Aff4	ENSMUSG00000049470	0.0880615565264046	0.132092334789607	0.0523032931247597	0.132092334789607	0.513665062682276	0.513665062682276
Rictor	ENSMUSG00000050310	0.21549027811633	0.21549027811633	0.0592616003460512	0.177784801038154	0.146141353215796	0.21549027811633
Zfp61	ENSMUSG00000050605	0.200650219614881	0.601950658844642	0.777255087907932	0.777255087907932	0.639337105615664	0.777255087907932
Zfp169	ENSMUSG00000050954	0.456305241393103	0.456305241393103	0.00159435459956481	0.00478306379869442	0.300095920620218	0.450143880930327
Zfp11	ENSMUSG00000051034	1	1	0.392614583064079	0.588921874596118	0.119325847749354	0.357977543248062
Zfp455	ENSMUSG00000051037	0.577544706586058	0.926387617028817	0.926387617028817	0.926387617028817	0.853694531487825	0.926387617028817
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Zfp961	ENSMUSG00000052446	0.0763619660358786	0.114542949053818	0.124210209545128	0.124210209545128	0.0602750588006477	0.114542949053818
Zfp14	ENSMUSG00000053985	0.34837756124189	0.522566341862834	0.782117202022501	0.782117202022501	0.214764523938594	0.522566341862834
Mdm4	ENSMUSG00000054387	0.0436072256433733	0.0654108384650599	0.0113089139751576	0.0339267419254727	0.346899083932133	0.346899083932133
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Zfp101	ENSMUSG00000055240	0.392985378348026	0.746437832861452	0.497625221907634	0.746437832861452	0.852832278580641	0.852832278580641
Zfp458	ENSMUSG00000055480	0.513665062682276	0.770497594023414	0.0964252305385472	0.289275691615642	0.926441990075769	0.926441990075769
A430033K04Rik	ENSMUSG00000056014	0.348008842235185	0.522013263352777	0.0761127945805736	0.228338383741721	1	1
AI987944	ENSMUSG00000056383	0.0753654386865988	0.113048158029898	0.00468160475316412	0.0140448142594924	0.509144723230069	0.509144723230069
Zfp658	ENSMUSG00000056592	0.0236697127745138	0.0710091383235414	0.211110344399808	0.211110344399808	0.12085053136293	0.181275797044394
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
Zfp317	ENSMUSG00000057551	0.248769231421035	0.248769231421035	0.0592616003460512	0.166082403751097	0.110721602500731	0.166082403751097
Zfp595	ENSMUSG00000057842	0.0953125666339396	0.144637845807821	0.0964252305385474	0.144637845807821	0.5155648232968	0.5155648232968
Zfp420	ENSMUSG00000058402	0.576973746230334	0.865460619345501	0.926550375688041	0.926550375688041	0.0880615565264048	0.264184669579214
Rsl1	ENSMUSG00000058900	0.346527959006435	0.519791938509652	0.253294730253594	0.519791938509652	0.782117202022501	0.782117202022501
Zfp426	ENSMUSG00000059475	0.299349060054895	0.643359829732651	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651
Zfp74	ENSMUSG00000059975	0.5155648232968	0.7733472349452	1	1	0.455625354715449	0.7733472349452
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Zfp937	ENSMUSG00000060336	0.119936171404379	0.262038348050444	0.45596561163947	0.45596561163947	0.174692232033629	0.262038348050444
Zfp229	ENSMUSG00000061544	0.711034989117171	0.711034989117171	0.455625354715448	0.683438032073173	0.252920381501207	0.683438032073173
Zfp27	ENSMUSG00000062040	0.454942951775341	0.682414427663012	0.0958690133561599	0.28760704006848	0.926003599371282	0.926003599371282
Zfp398	ENSMUSG00000062519	0.577829325134931	0.577829325134931	0.024062085667391	0.0721862570021729	0.299349060054895	0.449023590082343
Zfp677	ENSMUSG00000062743	0.711240436189781	0.711240436189781	0.299349060054895	0.679320738524319	0.452880492349546	0.679320738524319
Zkscan8	ENSMUSG00000063894	0.514934023620344	0.514934023620344	0.178901132102684	0.514934023620344	0.346527959006435	0.514934023620344
Med14	ENSMUSG00000064127	0.0523032931247596	0.0784549396871394	0.014844565205092	0.044533695615276	0.78180291566155	0.78180291566155
Cenpj	ENSMUSG00000064128	0.179597906187076	0.269396859280614	0.17855224077719	0.269396859280614	0.6976092207787	0.6976092207787
Zfp932	ENSMUSG00000066613	0.236337185850513	0.341647690705446	0.249907451332337	0.341647690705446	0.341647690705446	0.341647690705446
Zfp563	ENSMUSG00000067424	0.569937449249116	0.569937449249116	0.27173234335943	0.569937449249116	0.508488713161374	0.569937449249116
Zfp763	ENSMUSG00000067430	0.255901190956604	0.767703572869812	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739
Prkag1	ENSMUSG00000067713	0.00481536616919077	0.00722304925378615	0.000164597779190222	0.000493793337570666	0.711240436189781	0.711240436189781
Zfp442	ENSMUSG00000068130	0.0753654386865988	0.113048158029898	0.058823267388015	0.113048158029898	0.300095920620218	0.300095920620218
1700049G17Rik	ENSMUSG00000070709	0.254414773803597	0.381622160705395	0.236337185850513	0.381622160705395	0.575536202757516	0.575536202757516
Cited4	ENSMUSG00000070803	0.147458757705094	0.148772260628989	0.0164739112492867	0.0494217337478601	0.148772260628989	0.148772260628989
Zfp942	ENSMUSG00000071267	0.180293335960318	0.324321520550992	0.216214347033994	0.324321520550992	0.576973746230334	0.576973746230334
Zfp9	ENSMUSG00000072623	0.214037080764326	0.324321520550992	0.514300775319626	0.514300775319626	0.216214347033995	0.324321520550992
Etohi1	ENSMUSG00000074519	0.0171027900598199	0.0256541850897299	0.000373355180054072	0.00112006554016222	0.511742979522636	0.511742979522636
5830428H23Rik	ENSMUSG00000074733	0.0238002551499929	0.0357003827249894	5.62387620362729e-05	0.000168716286108819	0.346527959006435	0.346527959006435
Rslcan18	ENSMUSG00000074824	0.000387171985540247	0.00116151595662074	0.255901190956604	0.346899083932133	0.346899083932133	0.346899083932133
Ywhaq	ENSMUSG00000076432	0.342026805366747	0.853372965654504	0.853372965654504	0.853372965654504	0.576973746230334	0.853372965654504
Gm14420	ENSMUSG00000078866	0.000795094181770697	0.00238528254531209	0.058823267388015	0.0882349010820225	0.926550375688041	0.926550375688041
Gm14391	ENSMUSG00000078903	0.117185073436597	0.351555220309791	0.395928178642446	0.593892267963669	0.78180291566155	0.78180291566155
Med12	ENSMUSG00000079487	0.197598874030478	0.377126938563765	0.25141795904251	0.377126938563765	1	1
Zfp111	ENSMUSG00000087598	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.346527959006435	0.926550375688041
Zfp882	ENSMUSG00000089857	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028	0.144820068500793	0.21723010275119
Gm14399	ENSMUSG00000090093	5.46967066778586e-05	0.000164090120033576	0.0449262652924809	0.0673893979387214	0.643359829732651	0.643359829732651
Gm5141	ENSMUSG00000091183	0.173632433887832	0.520897301663497	0.640861491578951	0.640861491578951	0.575536202757516	0.640861491578951
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
Zfp964	ENSMUSG00000091764	0.926550375688041	0.926550375688041	0.148115998140416	0.444347994421247	0.853372965654504	0.926550375688041
Sco2	ENSMUSG00000091780	0.513665062682276	0.573498913947369	0.0168921052924602	0.0506763158773805	0.573498913947369	0.573498913947369
Gm4767	ENSMUSG00000094076	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282
Zfp748	ENSMUSG00000095432	0.452880492349546	0.452880492349546	0.0168921052924602	0.0506763158773805	0.334715083204388	0.452880492349546
Gm10778	ENSMUSG00000096856	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282

Download data as csv

Generic Transcription Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox5a	ENSMUSG00000000088	0.255901190956604	0.383851786434906	5.17062302895136e-05	0.000155118690868541	0.852504981253341	0.852504981253341
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Zfp40	ENSMUSG00000002617	0.452880492349546	0.679320738524319	0.0117179415987428	0.0351538247962283	0.78180291566155	0.78180291566155
Cdk12	ENSMUSG00000003119	0.853694531487825	0.853694531487825	0.0753654386865988	0.226096316059796	0.643359829732651	0.853694531487825
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Hipk1	ENSMUSG00000008730	0.342026805366747	0.513665062682276	0.509144723230069	0.513665062682276	0.513665062682276	0.513665062682276
Zfp790	ENSMUSG00000011427	0.058823267388015	0.176469802164045	0.455625354715449	0.455625354715449	0.256271555563966	0.384407333345949
Tbp	ENSMUSG00000014767	0.179945789077372	0.269918683616058	0.0241933715424143	0.0725801146272428	0.926550375688041	0.926550375688041
Med1	ENSMUSG00000018160	0.643853282854191	0.643853282854191	0.0743693776059064	0.223108132817719	0.347639524025037	0.521459286037555
Smurf2	ENSMUSG00000018363	0.117185073436597	0.175777610154895	0.0936419271039908	0.175777610154895	0.576973746230334	0.576973746230334
Chd3	ENSMUSG00000018474	0.0441715176243982	0.132514552873195	0.297848640636702	0.446772960955053	0.853694531487825	0.853694531487825
Cnot2	ENSMUSG00000020166	0.397384062266614	0.596076093399921	0.0150443553124285	0.0451330659372854	0.92416823462528	0.92416823462528
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Cnot6	ENSMUSG00000020362	0.283930443883615	0.288654423610209	0.0148445652050919	0.0445336956152758	0.288654423610209	0.288654423610209
Cnot8	ENSMUSG00000020515	0.17750354896016	0.26625532344024	0.0566379395854602	0.169913818756381	0.57466664340579	0.57466664340579
Prelid1	ENSMUSG00000021486	0.113498953177704	0.120850531362929	0.120850531362929	0.120850531362929	0.0231661970063528	0.0694985910190584
A530054K11Rik	ENSMUSG00000021510	0.146141353215796	0.219212029823694	0.0101222094973346	0.0303666284920038	0.711034989117171	0.711034989117171
Nr1d2	ENSMUSG00000021775	0.926658283600152	0.926658283600152	0.0964252305385471	0.289275691615641	0.347639524025037	0.521459286037555
Bnip3l	ENSMUSG00000022051	0.0964252305385471	0.144637845807821	0.00943994294581103	0.0283198288374331	0.514300775319626	0.514300775319626
Atad2	ENSMUSG00000022360	0.576973746230334	0.576973746230334	0.0097403746490101	0.0292211239470303	0.342405296020881	0.513607944031322
Zfp263	ENSMUSG00000022529	0.515249728559994	0.642117186565222	0.096147151118103	0.288441453354309	0.642117186565222	0.642117186565222
Nr4a1	ENSMUSG00000023034	0.513026869856283	0.513026869856283	0.180293335960318	0.270440003940477	0.178901132102685	0.270440003940477
Zfp51	ENSMUSG00000023892	0.120850531362929	0.120850531362929	0.116265430850263	0.120850531362929	0.0969812105731563	0.120850531362929
Pdpk1	ENSMUSG00000024122	0.288654423610209	0.288654423610209	0.0334587898203824	0.100376369461147	0.091411676944639	0.137117515416958
Epc1	ENSMUSG00000024240	0.0969812105731562	0.145471815859734	0.0441715176243983	0.132514552873195	0.711854160331342	0.711854160331342
Zfp871	ENSMUSG00000024298	0.0766111619812295	0.114916742971844	0.0588232673880149	0.114916742971844	0.148115998140415	0.148115998140415
Lrdd	ENSMUSG00000025507	0.853480389728993	0.853480389728993	0.254414773803597	0.763244321410791	0.853372965654504	0.853480389728993
Psmd1	ENSMUSG00000026229	0.707899741868332	0.707899741868332	0.628654363853655	0.707899741868332	0.0847074989275803	0.254122496782741
Ccnt2	ENSMUSG00000026349	0.246861959455465	0.246861959455465	0.0334587898203823	0.100376369461147	0.243396309647536	0.246861959455465
Rbbp5	ENSMUSG00000026439	0.926333123228344	0.926333123228344	0.179945789077372	0.269918683616058	0.0553321944628786	0.165996583388636
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Tpx2	ENSMUSG00000027469	0.642366752097095	0.926333123228344	0.0592616003460512	0.177784801038154	0.926333123228344	0.926333123228344
Itch	ENSMUSG00000027598	0.455625354715449	0.455625354715449	0.348008842235184	0.455625354715449	0.454600801949284	0.455625354715449
Trp53inp1	ENSMUSG00000028211	0.147458757705095	0.268351698154027	0.782117202022501	0.782117202022501	0.178901132102685	0.268351698154027
Ccne2	ENSMUSG00000028212	0.180293335960318	0.270440003940478	0.0451153644990945	0.135346093497283	0.7802108304765	0.7802108304765
Nbn	ENSMUSG00000028224	0.216214347033994	0.324321520550991	0.0426702157436794	0.128010647231038	0.853801250889739	0.853801250889739
Ccnc	ENSMUSG00000028252	0.453570536021945	0.680355804032917	0.711034989117171	0.711034989117171	0.399548817627028	0.680355804032917
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Trp73	ENSMUSG00000029026	0.631140429608896	0.631140429608896	0.336273664439462	0.631140429608896	0.441110460794563	0.631140429608896
Polr2b	ENSMUSG00000029250	0.348008842235184	0.348008842235184	0.348008842235184	0.348008842235184	0.148115998140416	0.348008842235184
Gtf2h3	ENSMUSG00000029387	0.562539849036184	0.563799176258241	0.450444934184774	0.563799176258241	0.563799176258241	0.563799176258241
Zfp12	ENSMUSG00000029587	0.148115998140415	0.444347994421246	0.346527959006435	0.455625354715449	0.455625354715449	0.455625354715449
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Kras	ENSMUSG00000030265	0.120545895661628	0.180818843492441	0.00768144932639895	0.0230443479791968	0.926658283600152	0.926658283600152
Zfp606	ENSMUSG00000030386	0.513665062682276	0.711854160331342	0.711854160331342	0.711854160331342	0.514934023620345	0.711854160331342
Zfp583	ENSMUSG00000030443	0.0100452863122198	0.0301358589366594	0.778747761033626	0.778747761033626	0.0955908182073974	0.143386227311096
Zfp626	ENSMUSG00000030604	0.7048795965722	0.7048795965722	0.0451153644990944	0.135346093497283	0.342026805366747	0.51304020805012
Tead2	ENSMUSG00000030796	1	1	0.300095920620217	0.900287761860652	0.782117202022501	1
Wrn	ENSMUSG00000031583	0.92589277149125	0.92589277149125	0.004463251977831	0.013389755933493	0.023800255149993	0.0357003827249895
Cox4i1	ENSMUSG00000031818	0.148772260628989	0.223158390943484	0.00283103937188884	0.00849311811566651	0.344663224299303	0.344663224299303
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Chek1	ENSMUSG00000032113	0.9255572759333	0.9255572759333	0.451840588205062	0.9255572759333	0.777255087907932	0.9255572759333
Rnf111	ENSMUSG00000032217	0.343537039781257	0.450444934184774	0.399548817627028	0.450444934184774	0.450444934184774	0.450444934184774
Arid2	ENSMUSG00000033237	0.395562602091096	0.852723421673413	0.711854160331342	0.852723421673413	0.852723421673413	0.852723421673413
Mga	ENSMUSG00000033943	0.250285839267991	0.250285839267991	0.0953125666339397	0.250285839267991	0.211110344399808	0.250285839267991
Med13	ENSMUSG00000034297	0.120545895661627	0.180818843492441	0.00159435459956481	0.00478306379869444	0.926003599371282	0.926003599371282
Cnot6l	ENSMUSG00000034724	0.398108175780842	0.398108175780842	0.0230207752632622	0.0345311628948933	0.016682476544732	0.0345311628948933
Zfp661	ENSMUSG00000034800	0.0579478375430677	0.142133847148433	0.0947558980989551	0.142133847148433	0.852940894477647	0.852940894477647
Mbd3	ENSMUSG00000035478	0.00743512899358789	0.011336675467394	0.0075577836449293	0.011336675467394	1	1
Zfp157	ENSMUSG00000036898	0.348008842235184	0.522013263352776	0.0432318933800775	0.129695680140233	0.575824878403157	0.575824878403157
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Smurf1	ENSMUSG00000038780	0.298599969973533	0.447899954960299	0.0579478375430677	0.173843512629203	0.926550375688041	0.926550375688041
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
H2afv	ENSMUSG00000041126	0.0115535350288052	0.0173303025432078	0.00477055016690543	0.0143116505007163	0.45596561163947	0.45596561163947
Cdk13	ENSMUSG00000041297	0.450094379653806	0.570836132666921	0.115651627788147	0.346954883364442	0.570836132666921	0.570836132666921
Pbrm1	ENSMUSG00000042323	0.511742979522636	0.511742979522636	0.0575107614292585	0.172532284287776	0.400265374208515	0.511742979522636
Gatad2b	ENSMUSG00000042390	0.455625354715448	0.455625354715448	0.346527959006435	0.455625354715448	0.255901190956604	0.455625354715448
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Zfp445	ENSMUSG00000047036	0.171859370212435	0.171859370212435	0.0419238354397912	0.125771506319374	0.138156294413154	0.171859370212435
Slc38a9	ENSMUSG00000047789	0.300095920620218	0.450143880930327	0.298599969973533	0.450143880930327	0.578113371816017	0.578113371816017
Zfp473	ENSMUSG00000048012	0.180293335960318	0.540880007880954	0.643853282854191	0.643853282854191	0.578113371816017	0.643853282854191
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Zfp738	ENSMUSG00000048280	0.0171027900598199	0.0360931285010865	0.024062085667391	0.0360931285010865	0.345410946355104	0.345410946355104
Rictor	ENSMUSG00000050310	0.21549027811633	0.21549027811633	0.0592616003460512	0.177784801038154	0.146141353215796	0.21549027811633
Zfp61	ENSMUSG00000050605	0.200650219614881	0.601950658844642	0.777255087907932	0.777255087907932	0.639337105615664	0.777255087907932
Zfp169	ENSMUSG00000050954	0.456305241393103	0.456305241393103	0.00159435459956481	0.00478306379869442	0.300095920620218	0.450143880930327
Zfp11	ENSMUSG00000051034	1	1	0.392614583064079	0.588921874596118	0.119325847749354	0.357977543248062
Zfp455	ENSMUSG00000051037	0.577544706586058	0.926387617028817	0.926387617028817	0.926387617028817	0.853694531487825	0.926387617028817
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Zfp961	ENSMUSG00000052446	0.0763619660358786	0.114542949053818	0.124210209545128	0.124210209545128	0.0602750588006477	0.114542949053818
Zfp14	ENSMUSG00000053985	0.34837756124189	0.522566341862834	0.782117202022501	0.782117202022501	0.214764523938594	0.522566341862834
Mdm4	ENSMUSG00000054387	0.0436072256433733	0.0654108384650599	0.0113089139751576	0.0339267419254727	0.346899083932133	0.346899083932133
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Zfp101	ENSMUSG00000055240	0.392985378348026	0.746437832861452	0.497625221907634	0.746437832861452	0.852832278580641	0.852832278580641
Zfp458	ENSMUSG00000055480	0.513665062682276	0.770497594023414	0.0964252305385472	0.289275691615642	0.926441990075769	0.926441990075769
A430033K04Rik	ENSMUSG00000056014	0.348008842235185	0.522013263352777	0.0761127945805736	0.228338383741721	1	1
AI987944	ENSMUSG00000056383	0.0753654386865988	0.113048158029898	0.00468160475316412	0.0140448142594924	0.509144723230069	0.509144723230069
Zfp658	ENSMUSG00000056592	0.0236697127745138	0.0710091383235414	0.211110344399808	0.211110344399808	0.12085053136293	0.181275797044394
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
Zfp317	ENSMUSG00000057551	0.248769231421035	0.248769231421035	0.0592616003460512	0.166082403751097	0.110721602500731	0.166082403751097
Zfp595	ENSMUSG00000057842	0.0953125666339396	0.144637845807821	0.0964252305385474	0.144637845807821	0.5155648232968	0.5155648232968
Zfp420	ENSMUSG00000058402	0.576973746230334	0.865460619345501	0.926550375688041	0.926550375688041	0.0880615565264048	0.264184669579214
Rsl1	ENSMUSG00000058900	0.346527959006435	0.519791938509652	0.253294730253594	0.519791938509652	0.782117202022501	0.782117202022501
Zfp426	ENSMUSG00000059475	0.299349060054895	0.643359829732651	0.5155648232968	0.643359829732651	0.643359829732651	0.643359829732651
Zfp74	ENSMUSG00000059975	0.5155648232968	0.7733472349452	1	1	0.455625354715449	0.7733472349452
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Zfp937	ENSMUSG00000060336	0.119936171404379	0.262038348050444	0.45596561163947	0.45596561163947	0.174692232033629	0.262038348050444
Zfp229	ENSMUSG00000061544	0.711034989117171	0.711034989117171	0.455625354715448	0.683438032073173	0.252920381501207	0.683438032073173
Zfp27	ENSMUSG00000062040	0.454942951775341	0.682414427663012	0.0958690133561599	0.28760704006848	0.926003599371282	0.926003599371282
Zfp398	ENSMUSG00000062519	0.577829325134931	0.577829325134931	0.024062085667391	0.0721862570021729	0.299349060054895	0.449023590082343
Zfp677	ENSMUSG00000062743	0.711240436189781	0.711240436189781	0.299349060054895	0.679320738524319	0.452880492349546	0.679320738524319
Zkscan8	ENSMUSG00000063894	0.514934023620344	0.514934023620344	0.178901132102684	0.514934023620344	0.346527959006435	0.514934023620344
Med14	ENSMUSG00000064127	0.0523032931247596	0.0784549396871394	0.014844565205092	0.044533695615276	0.78180291566155	0.78180291566155
Cenpj	ENSMUSG00000064128	0.179597906187076	0.269396859280614	0.17855224077719	0.269396859280614	0.6976092207787	0.6976092207787
Zfp932	ENSMUSG00000066613	0.236337185850513	0.341647690705446	0.249907451332337	0.341647690705446	0.341647690705446	0.341647690705446
Zfp563	ENSMUSG00000067424	0.569937449249116	0.569937449249116	0.27173234335943	0.569937449249116	0.508488713161374	0.569937449249116
Zfp763	ENSMUSG00000067430	0.255901190956604	0.767703572869812	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739
Prkag1	ENSMUSG00000067713	0.00481536616919077	0.00722304925378615	0.000164597779190222	0.000493793337570666	0.711240436189781	0.711240436189781
Zfp442	ENSMUSG00000068130	0.0753654386865988	0.113048158029898	0.058823267388015	0.113048158029898	0.300095920620218	0.300095920620218
1700049G17Rik	ENSMUSG00000070709	0.254414773803597	0.381622160705395	0.236337185850513	0.381622160705395	0.575536202757516	0.575536202757516
Cited4	ENSMUSG00000070803	0.147458757705094	0.148772260628989	0.0164739112492867	0.0494217337478601	0.148772260628989	0.148772260628989
Zfp942	ENSMUSG00000071267	0.180293335960318	0.324321520550992	0.216214347033994	0.324321520550992	0.576973746230334	0.576973746230334
Zfp9	ENSMUSG00000072623	0.214037080764326	0.324321520550992	0.514300775319626	0.514300775319626	0.216214347033995	0.324321520550992
Etohi1	ENSMUSG00000074519	0.0171027900598199	0.0256541850897299	0.000373355180054072	0.00112006554016222	0.511742979522636	0.511742979522636
5830428H23Rik	ENSMUSG00000074733	0.0238002551499929	0.0357003827249894	5.62387620362729e-05	0.000168716286108819	0.346527959006435	0.346527959006435
Rslcan18	ENSMUSG00000074824	0.000387171985540247	0.00116151595662074	0.255901190956604	0.346899083932133	0.346899083932133	0.346899083932133
Ywhaq	ENSMUSG00000076432	0.342026805366747	0.853372965654504	0.853372965654504	0.853372965654504	0.576973746230334	0.853372965654504
Gm14420	ENSMUSG00000078866	0.000795094181770697	0.00238528254531209	0.058823267388015	0.0882349010820225	0.926550375688041	0.926550375688041
Gm14391	ENSMUSG00000078903	0.117185073436597	0.351555220309791	0.395928178642446	0.593892267963669	0.78180291566155	0.78180291566155
Med12	ENSMUSG00000079487	0.197598874030478	0.377126938563765	0.25141795904251	0.377126938563765	1	1
Zfp111	ENSMUSG00000087598	0.78180291566155	0.926550375688041	0.926550375688041	0.926550375688041	0.346527959006435	0.926550375688041
Zfp882	ENSMUSG00000089857	0.072378961026407	0.217136883079221	0.399548817627028	0.399548817627028	0.144820068500793	0.21723010275119
Gm14399	ENSMUSG00000090093	5.46967066778586e-05	0.000164090120033576	0.0449262652924809	0.0673893979387214	0.643359829732651	0.643359829732651
Gm5141	ENSMUSG00000091183	0.173632433887832	0.520897301663497	0.640861491578951	0.640861491578951	0.575536202757516	0.640861491578951
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
Zfp964	ENSMUSG00000091764	0.926550375688041	0.926550375688041	0.148115998140416	0.444347994421247	0.853372965654504	0.926550375688041
Sco2	ENSMUSG00000091780	0.513665062682276	0.573498913947369	0.0168921052924602	0.0506763158773805	0.573498913947369	0.573498913947369
Gm4767	ENSMUSG00000094076	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282
Zfp748	ENSMUSG00000095432	0.452880492349546	0.452880492349546	0.0168921052924602	0.0506763158773805	0.334715083204388	0.452880492349546
Gm10778	ENSMUSG00000096856	0.926003599371282	0.926003599371282	0.255530331334265	0.766590994002796	0.640355507848752	0.926003599371282

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SUMOylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Ikbkg	ENSMUSG00000004221	0.295581119060361	0.392985378348026	0.11810342389482	0.354310271684459	0.392985378348026	0.392985378348026
Top2b	ENSMUSG00000017485	0.144820068500793	0.21723010275119	0.142830916318171	0.21723010275119	0.710208797518812	0.710208797518812
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Smc6	ENSMUSG00000020608	0.253294730253594	0.379942095380391	0.144820068500793	0.379942095380391	0.926658283600152	0.926658283600152
Trim27	ENSMUSG00000021326	0.0303111090728679	0.0454666636093019	0.0168921052924601	0.0454666636093019	1	1
Senp5	ENSMUSG00000022772	0.452880492349546	0.452880492349546	0.0140567816599278	0.022266847807638	0.014844565205092	0.022266847807638
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Sp3	ENSMUSG00000027109	0.0432318933800775	0.0648478400701162	0.00070197224802139	0.00210591674406417	0.7802108304765	0.7802108304765
Casp8ap2	ENSMUSG00000028282	0.0241933715424142	0.0362900573136213	0.0171027900598199	0.0362900573136213	0.850721744111585	0.850721744111585
Park7	ENSMUSG00000028964	0.0579478375430677	0.146800541856249	0.118714930081337	0.146800541856249	0.146800541856249	0.146800541856249
Xpc	ENSMUSG00000030094	0.852723421673413	0.852723421673413	0.641616487517698	0.852723421673413	0.711445446052875	0.852723421673413
Rad52	ENSMUSG00000030166	0.78180291566155	0.853801250889739	0.853480389728993	0.853801250889739	0.853801250889739	0.853801250889739
Senp1	ENSMUSG00000033075	0.926441990075769	0.926441990075769	0.146800541856249	0.440401625568746	0.346527959006435	0.519791938509652
Topors	ENSMUSG00000036822	0.297848640636702	0.446772960955053	0.058823267388015	0.176469802164045	0.456305241393103	0.456305241393103
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Trp53bp1	ENSMUSG00000043909	0.214037080764325	0.321055621146488	0.0312459040565944	0.0937377121697832	0.398829756175299	0.398829756175299
Nrip1	ENSMUSG00000048490	0.456305241393103	0.684457862089655	0.214037080764326	0.642111242292977	0.926658283600152	0.926658283600152
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Nupl1	ENSMUSG00000063895	0.105759219123975	0.158638828685963	0.00644160009194374	0.0193248002758312	0.194519294776045	0.194519294776045
Top1	ENSMUSG00000070544	0.115651627788147	0.173477441682221	0.00768144932639892	0.0230443479791968	0.640861491578951	0.640861491578951
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
Zfp131	ENSMUSG00000094870	0.291756209988535	0.437634314982803	0.0241933715424143	0.0725801146272428	0.926003599371282	0.926003599371282

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SUMO E3 ligases SUMOylate target proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Ikbkg	ENSMUSG00000004221	0.295581119060361	0.392985378348026	0.11810342389482	0.354310271684459	0.392985378348026	0.392985378348026
Top2b	ENSMUSG00000017485	0.144820068500793	0.21723010275119	0.142830916318171	0.21723010275119	0.710208797518812	0.710208797518812
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Smc6	ENSMUSG00000020608	0.253294730253594	0.379942095380391	0.144820068500793	0.379942095380391	0.926658283600152	0.926658283600152
Trim27	ENSMUSG00000021326	0.0303111090728679	0.0454666636093019	0.0168921052924601	0.0454666636093019	1	1
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Sp3	ENSMUSG00000027109	0.0432318933800775	0.0648478400701162	0.00070197224802139	0.00210591674406417	0.7802108304765	0.7802108304765
Casp8ap2	ENSMUSG00000028282	0.0241933715424142	0.0362900573136213	0.0171027900598199	0.0362900573136213	0.850721744111585	0.850721744111585
Park7	ENSMUSG00000028964	0.0579478375430677	0.146800541856249	0.118714930081337	0.146800541856249	0.146800541856249	0.146800541856249
Xpc	ENSMUSG00000030094	0.852723421673413	0.852723421673413	0.641616487517698	0.852723421673413	0.711445446052875	0.852723421673413
Rad52	ENSMUSG00000030166	0.78180291566155	0.853801250889739	0.853480389728993	0.853801250889739	0.853801250889739	0.853801250889739
Topors	ENSMUSG00000036822	0.297848640636702	0.446772960955053	0.058823267388015	0.176469802164045	0.456305241393103	0.456305241393103
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Trp53bp1	ENSMUSG00000043909	0.214037080764325	0.321055621146488	0.0312459040565944	0.0937377121697832	0.398829756175299	0.398829756175299
Nrip1	ENSMUSG00000048490	0.456305241393103	0.684457862089655	0.214037080764326	0.642111242292977	0.926658283600152	0.926658283600152
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Nupl1	ENSMUSG00000063895	0.105759219123975	0.158638828685963	0.00644160009194374	0.0193248002758312	0.194519294776045	0.194519294776045
Top1	ENSMUSG00000070544	0.115651627788147	0.173477441682221	0.00768144932639892	0.0230443479791968	0.640861491578951	0.640861491578951
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
Zfp131	ENSMUSG00000094870	0.291756209988535	0.437634314982803	0.0241933715424143	0.0725801146272428	0.926003599371282	0.926003599371282

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Chromatin modifying enzymes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Ncoa2	ENSMUSG00000005886	0.780049698709835	0.780049698709835	0.178901132102685	0.448462191467151	0.298974794311434	0.448462191467151
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Chd3	ENSMUSG00000018474	0.0441715176243982	0.132514552873195	0.297848640636702	0.446772960955053	0.853694531487825	0.853694531487825
Kdm6b	ENSMUSG00000018476	0.852504981253341	0.852504981253341	0.399548817627028	0.852504981253341	0.643359829732651	0.852504981253341
Arid5b	ENSMUSG00000019947	0.711650020253571	0.711650020253571	0.044926265292481	0.134778795877443	0.399548817627028	0.599323226440542
Kat6b	ENSMUSG00000021767	0.342026805366747	0.593892267963669	0.395928178642446	0.593892267963669	0.853480389728993	0.853480389728993
Phf17	ENSMUSG00000025764	0.0441715176243983	0.132514552873195	0.514934023620345	0.577829325134931	0.577829325134931	0.577829325134931
Rbbp5	ENSMUSG00000026439	0.926333123228344	0.926333123228344	0.179945789077372	0.269918683616058	0.0553321944628786	0.165996583388636
Ash1l	ENSMUSG00000028053	0.643853282854191	0.643853282854191	0.175044824745981	0.323235417174495	0.21549027811633	0.323235417174495
Kdm4c	ENSMUSG00000028397	0.853801250889739	0.853801250889739	0.21549027811633	0.324321520550992	0.216214347033995	0.324321520550992
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Rest	ENSMUSG00000029249	0.779888212132595	0.779888212132595	0.399548817627028	0.599323226440542	0.297848640636703	0.599323226440542
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Kdm5a	ENSMUSG00000030180	0.508488713161374	0.762733069742061	0.0129100470219435	0.0387301410658306	0.852175490580835	0.852175490580835
Atf7ip	ENSMUSG00000030213	0.711034989117171	0.711034989117171	0.400265374208515	0.711034989117171	0.578113371816017	0.711034989117171
Msl3	ENSMUSG00000031358	0.178901132102685	0.268351698154027	0.01710279005982	0.0513083701794599	0.455625354715448	0.455625354715448
Coprs	ENSMUSG00000031458	0.21549027811633	0.323235417174495	0.0588232673880149	0.176469802164045	0.926658283600152	0.926658283600152
Arid2	ENSMUSG00000033237	0.395562602091096	0.852723421673413	0.711854160331342	0.852723421673413	0.852723421673413	0.852723421673413
Mbd3	ENSMUSG00000035478	0.00743512899358789	0.011336675467394	0.0075577836449293	0.011336675467394	1	1
Setd7	ENSMUSG00000037111	0.454600801949285	0.514300775319626	0.0579478375430678	0.173843512629203	0.514300775319626	0.514300775319626
Phf16	ENSMUSG00000037315	0.0766111619812296	0.114916742971844	0.00637724014320526	0.0191317204296158	0.642366752097095	0.642366752097095
Kdm6a	ENSMUSG00000037369	0.297848640636702	0.297848640636702	0.174692232033629	0.297848640636702	0.295581119060361	0.297848640636702
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Pbrm1	ENSMUSG00000042323	0.511742979522636	0.511742979522636	0.0575107614292585	0.172532284287776	0.400265374208515	0.511742979522636
Gatad2b	ENSMUSG00000042390	0.455625354715448	0.455625354715448	0.346527959006435	0.455625354715448	0.255901190956604	0.455625354715448
Jhdm1d	ENSMUSG00000042599	0.252920381501207	0.37938057225181	0.00247508107184991	0.00742524321554973	0.640861491578951	0.640861491578951
Rps2	ENSMUSG00000044533	0.252920381501207	0.37938057225181	0.0331400397096514	0.0994201191289543	0.57466664340579	0.57466664340579
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Kdm3a	ENSMUSG00000053470	0.0103546374915853	0.0310639124747558	0.711240436189781	0.711240436189781	0.511097249598474	0.711240436189781
Whsc1l1	ENSMUSG00000054823	0.348008842235184	0.522013263352777	0.180293335960318	0.522013263352777	0.710416009055326	0.710416009055326
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
Suv420h2	ENSMUSG00000059851	0.295581119060361	0.447621891168214	0.447621891168214	0.447621891168214	0.346899083932133	0.447621891168214
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Suds3	ENSMUSG00000066900	0.120850531362929	0.181275797044394	0.00731348855817121	0.0219404656745136	0.853372965654504	0.853372965654504
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404

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Chromatin organization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kmt2a	ENSMUSG00000002028	0.299349060054895	0.449023590082343	0.0575107614292585	0.172532284287776	0.7802108304765	0.7802108304765
Ncoa2	ENSMUSG00000005886	0.780049698709835	0.780049698709835	0.178901132102685	0.448462191467151	0.298974794311434	0.448462191467151
Kmt2b	ENSMUSG00000006307	0.148772260628989	0.223158390943484	0.00755778364492931	0.0226733509347879	0.926658283600152	0.926658283600152
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arid1a	ENSMUSG00000007880	0.853372965654504	0.853372965654504	0.346527959006435	0.853372965654504	0.578113371816017	0.853372965654504
Chd3	ENSMUSG00000018474	0.0441715176243982	0.132514552873195	0.297848640636702	0.446772960955053	0.853694531487825	0.853694531487825
Kdm6b	ENSMUSG00000018476	0.852504981253341	0.852504981253341	0.399548817627028	0.852504981253341	0.643359829732651	0.852504981253341
Arid5b	ENSMUSG00000019947	0.711650020253571	0.711650020253571	0.044926265292481	0.134778795877443	0.399548817627028	0.599323226440542
Kat6b	ENSMUSG00000021767	0.342026805366747	0.593892267963669	0.395928178642446	0.593892267963669	0.853480389728993	0.853480389728993
Phf17	ENSMUSG00000025764	0.0441715176243983	0.132514552873195	0.514934023620345	0.577829325134931	0.577829325134931	0.577829325134931
Rbbp5	ENSMUSG00000026439	0.926333123228344	0.926333123228344	0.179945789077372	0.269918683616058	0.0553321944628786	0.165996583388636
Ash1l	ENSMUSG00000028053	0.643853282854191	0.643853282854191	0.175044824745981	0.323235417174495	0.21549027811633	0.323235417174495
Kdm4c	ENSMUSG00000028397	0.853801250889739	0.853801250889739	0.21549027811633	0.324321520550992	0.216214347033995	0.324321520550992
Kmt2e	ENSMUSG00000029004	0.346899083932133	0.520348625898199	0.299349060054895	0.520348625898199	0.575824878403157	0.575824878403157
Rest	ENSMUSG00000029249	0.779888212132595	0.779888212132595	0.399548817627028	0.599323226440542	0.297848640636703	0.599323226440542
Ezh2	ENSMUSG00000029687	0.399548817627028	0.511097249598474	0.0964252305385473	0.289275691615642	0.511097249598474	0.511097249598474
Kdm5a	ENSMUSG00000030180	0.508488713161374	0.762733069742061	0.0129100470219435	0.0387301410658306	0.852175490580835	0.852175490580835
Atf7ip	ENSMUSG00000030213	0.711034989117171	0.711034989117171	0.400265374208515	0.711034989117171	0.578113371816017	0.711034989117171
Msl3	ENSMUSG00000031358	0.178901132102685	0.268351698154027	0.01710279005982	0.0513083701794599	0.455625354715448	0.455625354715448
Coprs	ENSMUSG00000031458	0.21549027811633	0.323235417174495	0.0588232673880149	0.176469802164045	0.926658283600152	0.926658283600152
Arid2	ENSMUSG00000033237	0.395562602091096	0.852723421673413	0.711854160331342	0.852723421673413	0.852723421673413	0.852723421673413
Mbd3	ENSMUSG00000035478	0.00743512899358789	0.011336675467394	0.0075577836449293	0.011336675467394	1	1
Setd7	ENSMUSG00000037111	0.454600801949285	0.514300775319626	0.0579478375430678	0.173843512629203	0.514300775319626	0.514300775319626
Phf16	ENSMUSG00000037315	0.0766111619812296	0.114916742971844	0.00637724014320526	0.0191317204296158	0.642366752097095	0.642366752097095
Kdm6a	ENSMUSG00000037369	0.297848640636702	0.297848640636702	0.174692232033629	0.297848640636702	0.295581119060361	0.297848640636702
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Setd1b	ENSMUSG00000038384	0.577259514257969	0.577259514257969	0.0947558980989551	0.284267694296865	0.345410946355104	0.518116419532656
Pbrm1	ENSMUSG00000042323	0.511742979522636	0.511742979522636	0.0575107614292585	0.172532284287776	0.400265374208515	0.511742979522636
Gatad2b	ENSMUSG00000042390	0.455625354715448	0.455625354715448	0.346527959006435	0.455625354715448	0.255901190956604	0.455625354715448
Jhdm1d	ENSMUSG00000042599	0.252920381501207	0.37938057225181	0.00247508107184991	0.00742524321554973	0.640861491578951	0.640861491578951
Rps2	ENSMUSG00000044533	0.252920381501207	0.37938057225181	0.0331400397096514	0.0994201191289543	0.57466664340579	0.57466664340579
Kmt2d	ENSMUSG00000048154	0.643853282854191	0.643853282854191	0.0753654386865988	0.226096316059796	0.254414773803597	0.381622160705395
Prdm9	ENSMUSG00000051977	0.180293335960318	0.180293335960318	0.120850531362929	0.180293335960318	0.120850531362929	0.180293335960318
Kdm3a	ENSMUSG00000053470	0.0103546374915853	0.0310639124747558	0.711240436189781	0.711240436189781	0.511097249598474	0.711240436189781
Whsc1l1	ENSMUSG00000054823	0.348008842235184	0.522013263352777	0.180293335960318	0.522013263352777	0.710416009055326	0.710416009055326
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
Suv420h2	ENSMUSG00000059851	0.295581119060361	0.447621891168214	0.447621891168214	0.447621891168214	0.346899083932133	0.447621891168214
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Suds3	ENSMUSG00000066900	0.120850531362929	0.181275797044394	0.00731348855817121	0.0219404656745136	0.853372965654504	0.853372965654504
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404

Download data as csv

Membrane Trafficking

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Galnt1	ENSMUSG00000000420	0.179945789077372	0.269918683616058	0.00283103937188883	0.0084931181156665	0.852940894477647	0.852940894477647
Snapin	ENSMUSG00000001018	0.454600801949285	0.681901202923927	0.0404400620842031	0.121320186252609	1	1
Ap4e1	ENSMUSG00000001998	0.509144723230069	0.509144723230069	0.211844580334808	0.317766870502212	0.0908536824179312	0.272561047253794
Trappc6a	ENSMUSG00000002043	0.00731348855817119	0.0109702328372568	0.00463747559282086	0.0109702328372568	0.78180291566155	0.78180291566155
Bicd1	ENSMUSG00000003452	0.00755778364492929	0.0226733509347879	0.0432318933800775	0.0648478400701162	0.926658283600152	0.926658283600152
Chmp2b	ENSMUSG00000004843	0.567513221841557	0.706831781264721	0.706831781264721	0.706831781264721	0.167929015438905	0.503787046316716
Eps15l1	ENSMUSG00000006276	0.453225835454266	0.643359829732651	0.643359829732651	0.643359829732651	0.640861491578951	0.643359829732651
Kif5b	ENSMUSG00000006740	0.0171377151716892	0.0257065727575338	0.00885267753477384	0.0257065727575338	0.563799176258241	0.563799176258241
Vps4b	ENSMUSG00000009907	0.17924968721805	0.268874530827074	0.000248110195592023	0.000744330586776069	0.774176834800231	0.774176834800231
Kif11	ENSMUSG00000012443	0.21549027811633	0.323235417174495	0.0566379395854604	0.169913818756381	0.34837756124189	0.34837756124189
Ankrd28	ENSMUSG00000014496	0.343537039781257	0.515305559671886	0.0243249029874198	0.0729747089622593	0.634645058916812	0.634645058916812
Capza2	ENSMUSG00000015733	0.144820068500793	0.21723010275119	0.0140567816599278	0.0421703449797833	0.294820734456232	0.294820734456232
Vps45	ENSMUSG00000015747	0.0936419271039906	0.140462890655986	0.093084640707941	0.140462890655986	0.640355507848752	0.640355507848752
Gabarap	ENSMUSG00000018567	0.853480389728993	0.853480389728993	0.576112968612194	0.853480389728993	0.708745765211584	0.853480389728993
Cops3	ENSMUSG00000019373	0.45596561163947	0.683948417459205	0.252920381501207	0.683948417459205	0.782117202022501	0.782117202022501
Rab4a	ENSMUSG00000019478	0.848872227545608	0.848872227545608	0.058823267388015	0.16283148250234	0.108554321668227	0.16283148250234
Vps54	ENSMUSG00000020128	0.118409250205154	0.17761387530773	0.004463251977831	0.013389755933493	0.711854160331342	0.711854160331342
Actr2	ENSMUSG00000020152	0.256271555563966	0.256271555563966	0.146800541856249	0.256271555563966	0.216214347033995	0.256271555563966
Sptbn1	ENSMUSG00000020315	0.0562022152993846	0.0843033229490769	0.00143725611474427	0.00431176834423281	1	1
Arf5	ENSMUSG00000020440	0.013478096231532	0.020217144347298	0.00416720419511757	0.0125016125853527	0.642864324224729	0.642864324224729
Vamp2	ENSMUSG00000020894	0.34837756124189	0.400265374208515	0.178901132102685	0.400265374208515	0.400265374208515	0.400265374208515
Sec23a	ENSMUSG00000020986	0.113498953177704	0.175777610154895	0.117185073436597	0.175777610154895	0.454600801949285	0.454600801949285
Trip11	ENSMUSG00000021188	0.0164739112492867	0.0494217337478602	0.0583853430099098	0.0875780145148646	0.254787123615605	0.254787123615605
Trappc13	ENSMUSG00000021711	0.563485358844814	0.704440461749122	0.132079352483269	0.396238057449806	0.704440461749122	0.704440461749122
Bnip1	ENSMUSG00000024191	0.0312459040565944	0.0869217563146018	0.0579478375430679	0.0869217563146018	0.578113371816017	0.578113371816017
Napg	ENSMUSG00000024581	0.179945789077372	0.179945789077372	0.0116356061791785	0.0349068185375355	0.0434194723707708	0.0651292085561563
Dctn4	ENSMUSG00000024603	0.0230207752632622	0.0690623257897866	0.400265374208515	0.400265374208515	0.0575107614292585	0.0862661421438878
Kif20b	ENSMUSG00000024795	0.0763619660358785	0.114542949053818	0.0236697127745139	0.0710091383235418	0.397384062266614	0.397384062266614
Agfg1	ENSMUSG00000026159	0.216214347033995	0.324321520550992	0.0312459040565944	0.093737712169783	0.344663224299303	0.344663224299303
Optn	ENSMUSG00000026672	0.78180291566155	0.78180291566155	0.208156293081417	0.62446887924425	0.643359829732651	0.78180291566155
Ppp6c	ENSMUSG00000026753	0.0321889748775513	0.096566924632654	0.452880492349546	0.452880492349546	0.346527959006435	0.452880492349546
Golga1	ENSMUSG00000026754	0.0241933715424143	0.0725801146272428	0.711034989117171	0.711034989117171	0.209636747299873	0.314455120949809
Dnm1	ENSMUSG00000026825	0.0592616003460512	0.0888924005190769	0.0116356061791785	0.0349068185375355	0.513665062682276	0.513665062682276
Gapvd1	ENSMUSG00000026867	0.853694531487825	0.853694531487825	0.178901132102685	0.536703396308054	0.853694531487825	0.853694531487825
Dync1i2	ENSMUSG00000027012	0.0230207752632622	0.0690623257897866	0.144157978128026	0.216236967192039	0.5155648232968	0.5155648232968
Kif18a	ENSMUSG00000027115	0.63250023504486	0.63250023504486	0.31685435697757	0.63250023504486	0.449391287230099	0.63250023504486
Cops2	ENSMUSG00000027206	0.0588232673880149	0.176469802164045	0.17924968721805	0.268874530827074	1	1
Snap23	ENSMUSG00000027287	0.0325051220296005	0.0487576830444007	0.00429270217529417	0.0128781065258825	1	1
Chmp4c	ENSMUSG00000027536	0.148772260628989	0.223158390943484	0.0947558980989551	0.223158390943484	0.78180291566155	0.78180291566155
Sgip1	ENSMUSG00000028524	0.294820734456232	0.5155648232968	0.449391287230099	0.5155648232968	0.5155648232968	0.5155648232968
Eps15	ENSMUSG00000028552	0.208897379073412	0.313346068610118	0.00530065988358761	0.0159019796507628	0.573791743469336	0.573791743469336
Arpc1a	ENSMUSG00000029621	0.0334587898203824	0.0888924005190768	0.0592616003460512	0.0888924005190768	0.643853282854191	0.643853282854191
Tmf1	ENSMUSG00000030059	0.0741204440774081	0.111180666116112	0.0666744853474974	0.111180666116112	0.924286968561133	0.924286968561133
Dennd5b	ENSMUSG00000030313	0.058823267388015	0.176469802164045	0.178901132102685	0.268351698154027	0.926550375688041	0.926550375688041
Ctsc	ENSMUSG00000030560	0.635703516568383	0.635703516568383	5.02570344982356e-05	0.000150771103494707	0.624108087819719	0.635703516568383
Arfip2	ENSMUSG00000030881	0.9255572759333	0.926003599371282	0.9255572759333	0.926003599371282	0.926003599371282	0.926003599371282
Mvb12a	ENSMUSG00000031813	0.180293335960318	0.270440003940477	0.00481536616919077	0.0144460985075723	0.577829325134931	0.577829325134931
Rab27a	ENSMUSG00000032202	0.29252580908486	0.29252580908486	0.148772260628989	0.223158390943484	0.0756145297453648	0.223158390943484
Copb2	ENSMUSG00000032458	0.0575107614292585	0.172532284287776	0.21549027811633	0.323235417174495	0.853372965654504	0.853372965654504
Tmed7	ENSMUSG00000033184	0.924987846321933	0.924987846321933	0.447265995733381	0.924987846321933	0.638310022345193	0.924987846321933
Trappc8	ENSMUSG00000033382	0.174692232033629	0.511742979522636	0.392243127063687	0.511742979522636	0.511742979522636	0.511742979522636
Ston1	ENSMUSG00000033855	0.216214347033995	0.600398061312773	0.711650020253571	0.711650020253571	0.400265374208515	0.600398061312773
Golgb1	ENSMUSG00000034243	0.0723789610264069	0.10856844153961	0.0117179415987428	0.0351538247962283	0.711034989117171	0.711034989117171
Cbl	ENSMUSG00000034342	0.454600801949285	0.454600801949285	0.453570536021945	0.454600801949285	0.347639524025037	0.454600801949285
Pip5k1c	ENSMUSG00000034902	1	1	0.926550375688041	1	0.575536202757516	1
Cops4	ENSMUSG00000035297	0.348008842235184	0.522013263352776	0.00768144932639892	0.0230443479791968	1	1
Rabgap1	ENSMUSG00000035437	0.0676641944946709	0.202992583484013	0.144820068500793	0.21723010275119	0.779888212132595	0.779888212132595
Dync1li2	ENSMUSG00000035770	0.148772260628989	0.446316781886968	0.513665062682276	0.513665062682276	0.453570536021945	0.513665062682276
Sec24a	ENSMUSG00000036391	0.091411676944639	0.274235030833917	0.453225835454266	0.509144723230069	0.509144723230069	0.509144723230069
Kif15	ENSMUSG00000036768	0.390750658104794	0.586125987157192	0.0115535350288052	0.0346606050864156	0.92589277149125	0.92589277149125
Bicd2	ENSMUSG00000037933	0.0741204440774081	0.222361332232224	0.348008842235184	0.522013263352776	0.643853282854191	0.643853282854191
Dennd4c	ENSMUSG00000038024	0.0104326641569827	0.0312979924709482	0.342405296020881	0.342405296020881	0.288654423610209	0.342405296020881
Sbf2	ENSMUSG00000038371	0.513665062682276	0.513665062682276	0.180293335960318	0.513665062682276	0.449391287230099	0.513665062682276
Dennd2a	ENSMUSG00000038456	0.249907451332337	0.346527959006435	0.147458757705094	0.346527959006435	0.346527959006435	0.346527959006435
Golga4	ENSMUSG00000038708	0.255530331334266	0.522013263352776	0.348008842235184	0.522013263352776	0.578113371816017	0.578113371816017
Picalm	ENSMUSG00000039361	0.0763619660358786	0.220200812784373	0.146800541856249	0.220200812784373	0.782117202022501	0.782117202022501
Dennd6a	ENSMUSG00000040818	0.299349060054895	0.592794569471192	0.7802108304765	0.7802108304765	0.395196379647461	0.592794569471192
Fcho2	ENSMUSG00000041685	0.110102998658251	0.165154497987376	0.0703913497478892	0.165154497987376	0.847921313356738	0.847921313356738
Tbc1d8b	ENSMUSG00000042473	0.0129100470219435	0.0387301410658306	0.171503747555202	0.257255621332803	0.6978446011211	0.6978446011211
Vps37d	ENSMUSG00000043614	0.0113089139751576	0.0169633709627363	0.000373355180054071	0.00112006554016221	0.399548817627028	0.399548817627028
Sys1	ENSMUSG00000045503	0.120545895661628	0.180818843492441	0.0168921052924601	0.0506763158773803	0.392985378348026	0.392985378348026
Cltc	ENSMUSG00000047126	0.0443599545252852	0.133079863575856	0.194519294776045	0.291778942164068	0.635703516568382	0.635703516568382
Yipf6	ENSMUSG00000047694	0.0763619660358787	0.114542949053818	0.00145633884669441	0.00436901654008323	0.711034989117171	0.711034989117171
Agtr1a	ENSMUSG00000049115	0.295581119060361	0.295581119060361	0.0441715176243983	0.114916742971844	0.0766111619812296	0.114916742971844
Stam2	ENSMUSG00000055371	0.0756145297453646	0.113421794618047	0.0113089139751576	0.0339267419254727	0.643359829732651	0.643359829732651
Pla2g4a	ENSMUSG00000056220	0.338976281569376	0.642366752097095	0.642366752097095	0.642366752097095	0.507830090867449	0.642366752097095
Dennd1b	ENSMUSG00000056268	0.45149265530335	0.572321560317547	0.450444934184774	0.572321560317547	0.572321560317547	0.572321560317547
Bloc1s4	ENSMUSG00000060708	0.641616487517698	0.641616487517698	0.255158975839805	0.42529928657056	0.283532857713707	0.42529928657056
Copz1	ENSMUSG00000060992	0.0443599545252853	0.066539931787928	0.00412583181225651	0.0123774954367695	0.509144723230069	0.509144723230069
Fnbp1	ENSMUSG00000075415	0.711034989117171	0.92622377157404	0.92622377157404	0.92622377157404	0.573791743469336	0.92622377157404

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Cohesin Loading onto Chromatin

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nipbl	ENSMUSG00000022141	0.0723789610264069	0.17715513584223	0.11810342389482	0.17715513584223	0.453570536021945	0.453570536021945
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Wapal	ENSMUSG00000041408	0.0211129141819613	0.063338742545884	0.445116333668945	0.667674500503417	0.710001140920767	0.710001140920767

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Dbf4	ENSMUSG00000002297	0.641867098978197	0.926550375688041	0.0953125666339396	0.285937699901819	0.926550375688041	0.926550375688041
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Chmp2b	ENSMUSG00000004843	0.567513221841557	0.706831781264721	0.706831781264721	0.706831781264721	0.167929015438905	0.503787046316716
Pola1	ENSMUSG00000006678	0.298224585822431	0.397021051130446	0.00966484516254635	0.0289945354876391	0.397021051130446	0.397021051130446
Cdk4	ENSMUSG00000006728	0.178901132102685	0.268351698154027	0.17610058307789	0.268351698154027	0.853372965654504	0.853372965654504
Arpp19	ENSMUSG00000007656	0.0544641512383264	0.163392453714979	0.511097249598474	0.766645874397711	0.853694531487825	0.853694531487825
Anapc1	ENSMUSG00000014355	0.00143725611474427	0.00431176834423281	0.0325051220296005	0.0487576830444007	0.78180291566155	0.78180291566155
Ankrd28	ENSMUSG00000014496	0.343537039781257	0.515305559671886	0.0243249029874198	0.0729747089622593	0.634645058916812	0.634645058916812
Ppp1cb	ENSMUSG00000014956	0.254414773803597	0.254414773803597	0.0761127945805735	0.11416919187086	0.0721303428592823	0.11416919187086
Taok1	ENSMUSG00000017291	0.146800541856248	0.220200812784373	0.0404400620842031	0.121320186252609	0.398108175780842	0.398108175780842
Ppp1r12a	ENSMUSG00000019907	0.072627622984314	0.108941434476471	0.0566379395854602	0.108941434476471	1	1
Cep290	ENSMUSG00000019971	0.178901132102685	0.322146785907891	0.214764523938594	0.322146785907891	0.926441990075769	0.926441990075769
Mdm2	ENSMUSG00000020184	0.851732715229127	0.851732715229127	0.338976281569376	0.515305559671886	0.343537039781257	0.515305559671886
Hmmr	ENSMUSG00000020330	0.575536202757516	0.863304304136274	0.0761127945805736	0.228338383741721	1	1
Pttg1	ENSMUSG00000020415	0.345037391052887	0.7802108304765	0.576973746230334	0.7802108304765	0.7802108304765	0.7802108304765
Cenpo	ENSMUSG00000020652	1	1	0.0426702157436794	0.128010647231038	0.178901132102685	0.268351698154027
Cdc27	ENSMUSG00000020687	0.454942951775342	0.513665062682276	0.0328221470541517	0.098466441162455	0.513665062682276	0.513665062682276
Pole2	ENSMUSG00000020974	0.299349060054895	0.449023590082343	0.45596561163947	0.45596561163947	0.148115998140415	0.444347994421246
Rb1	ENSMUSG00000022105	0.0588232673880148	0.142133847148432	0.094755898098955	0.142133847148432	0.576112968612194	0.576112968612194
Nipbl	ENSMUSG00000022141	0.0723789610264069	0.17715513584223	0.11810342389482	0.17715513584223	0.453570536021945	0.453570536021945
Mzt2	ENSMUSG00000022671	0.0579478375430679	0.0869217563146018	0.00768144932639892	0.0230443479791968	0.447265995733381	0.447265995733381
Sgol1	ENSMUSG00000023940	0.400265374208515	0.600398061312773	0.148772260628989	0.446316781886967	0.852504981253341	0.852504981253341
Banf1	ENSMUSG00000024844	0.0164739112492867	0.0355045691617709	0.0236697127745139	0.0355045691617709	0.575824878403157	0.575824878403157
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Psmd1	ENSMUSG00000026229	0.707899741868332	0.707899741868332	0.628654363853655	0.707899741868332	0.0847074989275803	0.254122496782741
Ahctf1	ENSMUSG00000026491	0.513665062682276	0.513665062682276	0.174692232033629	0.262038348050444	0.148115998140416	0.262038348050444
Sdccag8	ENSMUSG00000026504	0.0953125666339396	0.285937699901819	0.254787123615605	0.382180685423408	0.45596561163947	0.45596561163947
Blzf1	ENSMUSG00000026577	0.0439832496172286	0.0659748744258429	0.0041258318122565	0.0123774954367695	0.85326530496423	0.85326530496423
Optn	ENSMUSG00000026672	0.78180291566155	0.78180291566155	0.208156293081417	0.62446887924425	0.643359829732651	0.78180291566155
Ppp6c	ENSMUSG00000026753	0.0321889748775513	0.096566924632654	0.452880492349546	0.452880492349546	0.346527959006435	0.452880492349546
Mastl	ENSMUSG00000026779	0.399548817627028	0.399548817627028	0.146141353215796	0.268874530827074	0.17924968721805	0.268874530827074
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Dync1i2	ENSMUSG00000027012	0.0230207752632622	0.0690623257897866	0.144157978128026	0.216236967192039	0.5155648232968	0.5155648232968
Kif18a	ENSMUSG00000027115	0.63250023504486	0.63250023504486	0.31685435697757	0.63250023504486	0.449391287230099	0.63250023504486
Tubgcp4	ENSMUSG00000027263	0.640861491578951	0.640861491578951	0.299349060054895	0.449023590082343	0.291756209988535	0.449023590082343
Casc5	ENSMUSG00000027326	0.347639524025037	0.5155648232968	0.146141353215796	0.438424059647387	0.5155648232968	0.5155648232968
Tpx2	ENSMUSG00000027469	0.642366752097095	0.926333123228344	0.0592616003460512	0.177784801038154	0.926333123228344	0.926333123228344
Chmp4c	ENSMUSG00000027536	0.148772260628989	0.223158390943484	0.0947558980989551	0.223158390943484	0.78180291566155	0.78180291566155
Ccne2	ENSMUSG00000028212	0.180293335960318	0.270440003940478	0.0451153644990945	0.135346093497283	0.7802108304765	0.7802108304765
Nbn	ENSMUSG00000028224	0.216214347033994	0.324321520550991	0.0426702157436794	0.128010647231038	0.853801250889739	0.853801250889739
Smc2	ENSMUSG00000028312	0.641867098978198	0.711650020253571	0.0074351289935879	0.0223053869807637	0.711650020253571	0.711650020253571
Cenpc1	ENSMUSG00000029253	0.116265430850263	0.174398146275395	0.091411676944639	0.174398146275395	0.297848640636702	0.297848640636702
Cdc7	ENSMUSG00000029283	0.400265374208515	0.400265374208515	0.216214347033995	0.400265374208515	0.400265374208515	0.400265374208515
Ankle2	ENSMUSG00000029501	0.926658283600152	0.926658283600152	0.346527959006435	0.519791938509652	0.297848640636702	0.519791938509652
Pole4	ENSMUSG00000030042	0.853694531487825	0.853694531487825	0.023800255149993	0.0714007654499789	0.711854160331342	0.853694531487825
Brcc3	ENSMUSG00000031201	0.0592616003460512	0.0888924005190768	0.0447373296833729	0.0888924005190768	0.852504981253341	0.852504981253341
Atrx	ENSMUSG00000031229	0.113498953177704	0.170248429766555	0.0432318933800775	0.129695680140232	0.576973746230334	0.576973746230334
Dkc1	ENSMUSG00000031403	0.0766111619812295	0.114916742971844	0.0243249029874197	0.0729747089622591	0.708534948098331	0.708534948098331
Gins4	ENSMUSG00000031546	0.572616808177226	0.572616808177226	0.254414773803597	0.446772960955053	0.297848640636702	0.446772960955053
Wrn	ENSMUSG00000031583	0.92589277149125	0.92589277149125	0.004463251977831	0.013389755933493	0.023800255149993	0.0357003827249895
Pcm1	ENSMUSG00000031592	0.00468160475316412	0.0140448142594924	0.0451153644990945	0.0676730467486417	0.926441990075769	0.926441990075769
Rbl2	ENSMUSG00000031666	0.179945789077372	0.539837367232115	0.398829756175299	0.598244634262948	1	1
Cep57	ENSMUSG00000031922	0.454942951775341	0.682414427663012	0.0953125666339397	0.285937699901819	0.853480389728993	0.853480389728993
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Chek1	ENSMUSG00000032113	0.9255572759333	0.9255572759333	0.451840588205062	0.9255572759333	0.777255087907932	0.9255572759333
Tubgcp5	ENSMUSG00000033790	0.853801250889739	0.853801250889739	0.513665062682276	0.853801250889739	0.643359829732651	0.853801250889739
Smc4	ENSMUSG00000034349	0.400265374208515	0.600398061312773	0.117185073436597	0.351555220309791	0.780851835278818	0.780851835278818
Dync1li2	ENSMUSG00000035770	0.148772260628989	0.446316781886968	0.513665062682276	0.513665062682276	0.453570536021945	0.513665062682276
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Haus6	ENSMUSG00000038047	0.926658283600152	0.926658283600152	0.400265374208515	0.600398061312773	0.400265374208515	0.600398061312773
Phf20	ENSMUSG00000038116	0.578113371816017	0.578113371816017	0.17924968721805	0.383851786434906	0.255901190956604	0.383851786434906
Cep250	ENSMUSG00000038241	0.853801250889739	0.853801250889739	0.710001140920767	0.853801250889739	0.399548817627028	0.853801250889739
Azi1	ENSMUSG00000039781	0.0239310464924689	0.0358965697387034	0.013959603844423	0.0358965697387034	0.570836132666921	0.570836132666921
H2afv	ENSMUSG00000041126	0.0115535350288052	0.0173303025432078	0.00477055016690543	0.0143116505007163	0.45596561163947	0.45596561163947
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Wapal	ENSMUSG00000041408	0.0211129141819613	0.063338742545884	0.445116333668945	0.667674500503417	0.710001140920767	0.710001140920767
Cep78	ENSMUSG00000041491	0.50716883916608	0.706616781330066	0.453225835454266	0.706616781330066	0.706616781330066	0.706616781330066
Trp53bp1	ENSMUSG00000043909	0.214037080764325	0.321055621146488	0.0312459040565944	0.0937377121697832	0.398829756175299	0.398829756175299
Mis18bp1	ENSMUSG00000047534	0.34837756124189	0.522566341862834	0.0763619660358786	0.229085898107636	0.926658283600152	0.926658283600152
Ercc6l	ENSMUSG00000051220	0.399548817627028	0.45596561163947	0.0583853430099097	0.175156029029729	0.45596561163947	0.45596561163947
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Mdm4	ENSMUSG00000054387	0.0436072256433733	0.0654108384650599	0.0113089139751576	0.0339267419254727	0.346899083932133	0.346899083932133
Cep110	ENSMUSG00000057110	0.926441990075769	0.926441990075769	0.147458757705095	0.442376273115284	0.5155648232968	0.7733472349452
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Rbbp4	ENSMUSG00000057236	0.0662963799459479	0.198889139837844	0.167929015438905	0.251893523158358	0.628654363853655	0.628654363853655
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Nupl1	ENSMUSG00000063895	0.105759219123975	0.158638828685963	0.00644160009194374	0.0193248002758312	0.194519294776045	0.194519294776045
Cenpj	ENSMUSG00000064128	0.179597906187076	0.269396859280614	0.17855224077719	0.269396859280614	0.6976092207787	0.6976092207787
Spdl1	ENSMUSG00000069910	0.9255572759333	0.9255572759333	0.233945590464139	0.701836771392419	0.565047747060087	0.84757162059013
Ywhaq	ENSMUSG00000076432	0.342026805366747	0.853372965654504	0.853372965654504	0.853372965654504	0.576973746230334	0.853372965654504
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
RNF8	ENSMUSG00000098374	0.346527959006435	0.346527959006435	0.0231500557096833	0.06945016712905	0.295581119060361	0.346527959006435

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Mitotic Prometaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Taok1	ENSMUSG00000017291	0.146800541856248	0.220200812784373	0.0404400620842031	0.121320186252609	0.398108175780842	0.398108175780842
Cep290	ENSMUSG00000019971	0.178901132102685	0.322146785907891	0.214764523938594	0.322146785907891	0.926441990075769	0.926441990075769
Cenpo	ENSMUSG00000020652	1	1	0.0426702157436794	0.128010647231038	0.178901132102685	0.268351698154027
Mzt2	ENSMUSG00000022671	0.0579478375430679	0.0869217563146018	0.00768144932639892	0.0230443479791968	0.447265995733381	0.447265995733381
Sgol1	ENSMUSG00000023940	0.400265374208515	0.600398061312773	0.148772260628989	0.446316781886967	0.852504981253341	0.852504981253341
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Ahctf1	ENSMUSG00000026491	0.513665062682276	0.513665062682276	0.174692232033629	0.262038348050444	0.148115998140416	0.262038348050444
Sdccag8	ENSMUSG00000026504	0.0953125666339396	0.285937699901819	0.254787123615605	0.382180685423408	0.45596561163947	0.45596561163947
Dync1i2	ENSMUSG00000027012	0.0230207752632622	0.0690623257897866	0.144157978128026	0.216236967192039	0.5155648232968	0.5155648232968
Kif18a	ENSMUSG00000027115	0.63250023504486	0.63250023504486	0.31685435697757	0.63250023504486	0.449391287230099	0.63250023504486
Tubgcp4	ENSMUSG00000027263	0.640861491578951	0.640861491578951	0.299349060054895	0.449023590082343	0.291756209988535	0.449023590082343
Casc5	ENSMUSG00000027326	0.347639524025037	0.5155648232968	0.146141353215796	0.438424059647387	0.5155648232968	0.5155648232968
Smc2	ENSMUSG00000028312	0.641867098978198	0.711650020253571	0.0074351289935879	0.0223053869807637	0.711650020253571	0.711650020253571
Cenpc1	ENSMUSG00000029253	0.116265430850263	0.174398146275395	0.091411676944639	0.174398146275395	0.297848640636702	0.297848640636702
Pcm1	ENSMUSG00000031592	0.00468160475316412	0.0140448142594924	0.0451153644990945	0.0676730467486417	0.926441990075769	0.926441990075769
Cep57	ENSMUSG00000031922	0.454942951775341	0.682414427663012	0.0953125666339397	0.285937699901819	0.853480389728993	0.853480389728993
Tubgcp5	ENSMUSG00000033790	0.853801250889739	0.853801250889739	0.513665062682276	0.853801250889739	0.643359829732651	0.853801250889739
Smc4	ENSMUSG00000034349	0.400265374208515	0.600398061312773	0.117185073436597	0.351555220309791	0.780851835278818	0.780851835278818
Dync1li2	ENSMUSG00000035770	0.148772260628989	0.446316781886968	0.513665062682276	0.513665062682276	0.453570536021945	0.513665062682276
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Haus6	ENSMUSG00000038047	0.926658283600152	0.926658283600152	0.400265374208515	0.600398061312773	0.400265374208515	0.600398061312773
Cep250	ENSMUSG00000038241	0.853801250889739	0.853801250889739	0.710001140920767	0.853801250889739	0.399548817627028	0.853801250889739
Azi1	ENSMUSG00000039781	0.0239310464924689	0.0358965697387034	0.013959603844423	0.0358965697387034	0.570836132666921	0.570836132666921
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Wapal	ENSMUSG00000041408	0.0211129141819613	0.063338742545884	0.445116333668945	0.667674500503417	0.710001140920767	0.710001140920767
Cep78	ENSMUSG00000041491	0.50716883916608	0.706616781330066	0.453225835454266	0.706616781330066	0.706616781330066	0.706616781330066
Ercc6l	ENSMUSG00000051220	0.399548817627028	0.45596561163947	0.0583853430099097	0.175156029029729	0.45596561163947	0.45596561163947
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Cep110	ENSMUSG00000057110	0.926441990075769	0.926441990075769	0.147458757705095	0.442376273115284	0.5155648232968	0.7733472349452
Cenpj	ENSMUSG00000064128	0.179597906187076	0.269396859280614	0.17855224077719	0.269396859280614	0.6976092207787	0.6976092207787
Spdl1	ENSMUSG00000069910	0.9255572759333	0.9255572759333	0.233945590464139	0.701836771392419	0.565047747060087	0.84757162059013

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SUMOylation of transcription cofactors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Casp8ap2	ENSMUSG00000028282	0.0241933715424142	0.0362900573136213	0.0171027900598199	0.0362900573136213	0.850721744111585	0.850721744111585
Park7	ENSMUSG00000028964	0.0579478375430677	0.146800541856249	0.118714930081337	0.146800541856249	0.146800541856249	0.146800541856249
Topors	ENSMUSG00000036822	0.297848640636702	0.446772960955053	0.058823267388015	0.176469802164045	0.456305241393103	0.456305241393103
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
Sin3a	ENSMUSG00000042557	0.255530331334266	0.766590994002797	0.642864324224729	0.782117202022501	0.782117202022501	0.782117202022501
Nrip1	ENSMUSG00000048490	0.456305241393103	0.684457862089655	0.214037080764326	0.642111242292977	0.926658283600152	0.926658283600152
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
Npm1	ENSMUSG00000057113	0.214037080764326	0.321055621146488	0.0766111619812296	0.229833485943689	0.576973746230334	0.576973746230334
Zfp131	ENSMUSG00000094870	0.291756209988535	0.437634314982803	0.0241933715424143	0.0725801146272428	0.926003599371282	0.926003599371282

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SUMOylation of DNA damage response and repair proteins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nup214	ENSMUSG00000001855	0.178901132102685	0.37938057225181	0.252920381501207	0.37938057225181	0.577829325134931	0.577829325134931
Ranbp2	ENSMUSG00000003226	0.058823267388015	0.0882349010820225	0.00283103937188883	0.0084931181156665	0.348008842235184	0.348008842235184
Smc6	ENSMUSG00000020608	0.253294730253594	0.379942095380391	0.144820068500793	0.379942095380391	0.926658283600152	0.926658283600152
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Bmi1	ENSMUSG00000026739	0.0964252305385472	0.212250051274902	0.141500034183268	0.212250051274902	0.781170242226513	0.781170242226513
Nup35	ENSMUSG00000026999	0.177153312234059	0.265729968351089	0.0209878658739169	0.0629635976217507	0.451840588205062	0.451840588205062
Xpc	ENSMUSG00000030094	0.852723421673413	0.852723421673413	0.641616487517698	0.852723421673413	0.711445446052875	0.852723421673413
Rad52	ENSMUSG00000030166	0.78180291566155	0.853801250889739	0.853480389728993	0.853801250889739	0.853801250889739	0.853801250889739
Pml	ENSMUSG00000036986	0.298599969973533	0.447899954960299	0.0936419271039908	0.280925781311972	0.575824878403157	0.575824878403157
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Phc3	ENSMUSG00000037652	0.508488713161374	0.508488713161374	0.294820734456232	0.508488713161374	0.392985378348026	0.508488713161374
Cbx4	ENSMUSG00000039989	0.577829325134931	0.577829325134931	0.454258017332816	0.577829325134931	0.298974794311434	0.577829325134931
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Nup160	ENSMUSG00000051329	0.453225835454266	0.679838753181399	0.0566379395854602	0.169913818756381	0.926658283600152	0.926658283600152
Nup107	ENSMUSG00000052798	0.5155648232968	0.5155648232968	0.0222505050945548	0.0667515152836645	0.148115998140416	0.222173997210623
Nupl1	ENSMUSG00000063895	0.105759219123975	0.158638828685963	0.00644160009194374	0.0193248002758312	0.194519294776045	0.194519294776045

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Mitotic Telophase/Cytokinesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nipbl	ENSMUSG00000022141	0.0723789610264069	0.17715513584223	0.11810342389482	0.17715513584223	0.453570536021945	0.453570536021945
Smc3	ENSMUSG00000024974	0.216214347033995	0.324321520550992	0.180293335960318	0.324321520550992	0.455625354715449	0.455625354715449
Stag2	ENSMUSG00000025862	0.058823267388015	0.0882349010820225	0.0038031455224948	0.0114094365674844	0.294820734456232	0.294820734456232
Stag1	ENSMUSG00000037286	0.148772260628989	0.223158390943483	0.144157978128026	0.223158390943483	0.392985378348026	0.392985378348026
Smc1a	ENSMUSG00000041133	0.216214347033995	0.324321520550992	0.0231500557096833	0.06945016712905	0.706831781264722	0.706831781264722
Wapal	ENSMUSG00000041408	0.0211129141819613	0.063338742545884	0.445116333668945	0.667674500503417	0.710001140920767	0.710001140920767

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DNA Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Baz1b	ENSMUSG00000002748	0.853801250889739	0.853801250889739	0.782117202022501	0.853801250889739	0.781170242226513	0.853801250889739
Msh6	ENSMUSG00000005370	0.711034989117171	0.711034989117171	0.454942951775341	0.711034989117171	0.708745765211584	0.711034989117171
Cops3	ENSMUSG00000019373	0.45596561163947	0.683948417459205	0.252920381501207	0.683948417459205	0.782117202022501	0.782117202022501
Pole2	ENSMUSG00000020974	0.299349060054895	0.449023590082343	0.45596561163947	0.45596561163947	0.148115998140415	0.444347994421246
Ercc4	ENSMUSG00000022545	0.853372965654504	0.926333123228344	0.57466664340579	0.926333123228344	0.926333123228344	0.926333123228344
Prkdc	ENSMUSG00000022672	0.712057867818062	0.712057867818062	0.514934023620345	0.712057867818062	0.300095920620218	0.712057867818062
Nhej1	ENSMUSG00000026162	0.00153425095635555	0.00460275286906664	0.514300775319626	0.514300775319626	0.392985378348026	0.514300775319626
Dclre1c	ENSMUSG00000026648	0.449391287230099	0.449391287230099	0.0138627169035502	0.0415881507106506	0.161774914569557	0.242662371854336
Cops2	ENSMUSG00000027206	0.0588232673880149	0.176469802164045	0.17924968721805	0.268874530827074	1	1
Dclre1b	ENSMUSG00000027845	0.0933633081328486	0.140044962199273	0.255158975839805	0.255158975839805	0.0721303428592825	0.140044962199273
Nbn	ENSMUSG00000028224	0.216214347033994	0.324321520550991	0.0426702157436794	0.128010647231038	0.853801250889739	0.853801250889739
Usp1	ENSMUSG00000028560	0.119631084167592	0.180818843492441	0.120545895661628	0.180818843492441	0.513026869856283	0.513026869856283
Polr2b	ENSMUSG00000029250	0.348008842235184	0.348008842235184	0.348008842235184	0.348008842235184	0.148115998140416	0.348008842235184
Gtf2h3	ENSMUSG00000029387	0.562539849036184	0.563799176258241	0.450444934184774	0.563799176258241	0.563799176258241	0.563799176258241
Ung	ENSMUSG00000029591	0.0443599545252854	0.133079863575856	0.144157978128026	0.216236967192039	0.575536202757516	0.575536202757516
Pole4	ENSMUSG00000030042	0.853694531487825	0.853694531487825	0.023800255149993	0.0714007654499789	0.711854160331342	0.853694531487825
Xpc	ENSMUSG00000030094	0.852723421673413	0.852723421673413	0.641616487517698	0.852723421673413	0.711445446052875	0.852723421673413
Rad52	ENSMUSG00000030166	0.78180291566155	0.853801250889739	0.853480389728993	0.853801250889739	0.853801250889739	0.853801250889739
C230052I12Rik	ENSMUSG00000030493	0.0226344734406829	0.0339517101610243	0.0166824765447319	0.0339517101610243	0.511742979522636	0.511742979522636
Cul4b	ENSMUSG00000031095	0.297848640636702	0.446772960955053	0.246861959455465	0.446772960955053	0.447621891168215	0.447621891168215
Brcc3	ENSMUSG00000031201	0.0592616003460512	0.0888924005190768	0.0447373296833729	0.0888924005190768	0.852504981253341	0.852504981253341
Wrn	ENSMUSG00000031583	0.92589277149125	0.92589277149125	0.004463251977831	0.013389755933493	0.023800255149993	0.0357003827249895
Mre11a	ENSMUSG00000031928	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.29252580908486	0.877577427254581
Sprtn	ENSMUSG00000031986	0.456305241393103	0.456305241393103	0.0360673631509441	0.108202089452832	0.337435786255283	0.456305241393103
Chek1	ENSMUSG00000032113	0.9255572759333	0.9255572759333	0.451840588205062	0.9255572759333	0.777255087907932	0.9255572759333
Rnf111	ENSMUSG00000032217	0.343537039781257	0.450444934184774	0.399548817627028	0.450444934184774	0.450444934184774	0.450444934184774
Mlh1	ENSMUSG00000032498	0.643359829732651	0.643359829732651	0.142165951159432	0.213248926739148	0.0523032931247597	0.156909879374279
Wdr48	ENSMUSG00000032512	0.255901190956604	0.383851786434905	0.0441715176243983	0.132514552873195	0.5155648232968	0.5155648232968
Cops4	ENSMUSG00000035297	0.348008842235184	0.522013263352776	0.00768144932639892	0.0230443479791968	1	1
Parp2	ENSMUSG00000036023	1	1	0.642366752097095	1	0.926550375688041	1
Rif1	ENSMUSG00000036202	0.0674166595311035	0.202249978593311	0.141500034183268	0.212250051274902	0.451840588205062	0.451840588205062
Uvssa	ENSMUSG00000037355	0.211844580334808	0.317766870502212	0.00264953297731415	0.00794859893194244	0.33859211714199	0.33859211714199
Eme1	ENSMUSG00000039055	0.711034989117171	0.711034989117171	0.211844580334808	0.635533741004424	0.578113371816017	0.711034989117171
Slx4	ENSMUSG00000039738	1	1	0.578113371816017	1	0.711034989117171	1
2810417H13Rik	ENSMUSG00000040204	0.853372965654504	0.853372965654504	0.0592616003460512	0.177784801038154	0.576973746230334	0.853372965654504
Usp45	ENSMUSG00000040455	0.553073349941124	0.553073349941124	0.124554674051006	0.373664022153019	0.475975540129638	0.553073349941124
Hmgn1	ENSMUSG00000040681	0.572616808177226	0.781170242226513	0.0443599545252853	0.133079863575856	0.781170242226513	0.781170242226513
Ino80d	ENSMUSG00000040865	0.148115998140415	0.222173997210623	0.0575107614292585	0.172532284287776	0.514934023620344	0.514934023620344
H2afv	ENSMUSG00000041126	0.0115535350288052	0.0173303025432078	0.00477055016690543	0.0143116505007163	0.45596561163947	0.45596561163947
Spidr	ENSMUSG00000041974	0.573498913947369	0.860248370921054	0.117185073436597	0.351555220309791	0.924987846321933	0.924987846321933
Trp53bp1	ENSMUSG00000043909	0.214037080764325	0.321055621146488	0.0312459040565944	0.0937377121697832	0.398829756175299	0.398829756175299
Lig4	ENSMUSG00000049717	0.179249687218049	0.522013263352777	0.348008842235184	0.522013263352777	0.577829325134931	0.577829325134931
Gen1	ENSMUSG00000051235	0.514934023620345	0.514934023620345	0.010906560635693	0.032719681907079	0.400265374208515	0.514934023620345
Ercc6	ENSMUSG00000054051	0.21549027811633	0.346527959006435	0.255901190956604	0.346527959006435	0.346527959006435	0.346527959006435
Ep300	ENSMUSG00000055024	0.514934023620345	0.514934023620345	0.148772260628989	0.446316781886968	0.513665062682276	0.514934023620345
H2afj	ENSMUSG00000060032	0.710208797518812	0.711650020253571	0.0733738589968007	0.220121576990402	0.711650020253571	0.711650020253571
Hist2h4	ENSMUSG00000091405	0.0434194723707708	0.130258417112312	0.180293335960318	0.270440003940477	0.92622377157404	0.92622377157404
RNF8	ENSMUSG00000098374	0.346527959006435	0.346527959006435	0.0231500557096833	0.06945016712905	0.295581119060361	0.346527959006435

Download data as csv

darkgoldenrod4

[1] “No significantly overrepresented pathways reported”

deepskyblue

[1] “No significantly overrepresented pathways reported”

firebrick

TNF signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nfkbia	ENSMUSG00000021025	0.455625354715448	0.636229315311352	0.636229315311352	0.636229315311352	0.399548817627028	0.636229315311352
Ripk3	ENSMUSG00000022221	0.0743693776059065	0.223108132817719	0.712057867818062	0.712057867818062	0.577829325134931	0.712057867818062
Sele	ENSMUSG00000026582	0.318167910726899	0.318167910726901	0.3181679107269	0.318167910726901	0.318167910726901	0.318167910726901
Cxcl5	ENSMUSG00000029371	0.110625408309088	0.331876224927265	0.921139684946258	0.921139684946258	0.456692624137623	0.685038936206434
Cxcl1	ENSMUSG00000029380	0.703333998861023	0.703333998861023	0.635966700067775	0.703333998861023	0.0499430342679683	0.149829102803905
Ccl2	ENSMUSG00000035385	0.511097249598474	0.701310685803632	0.701310685803632	0.701310685803632	0.379996064861382	0.701310685803632
Socs3	ENSMUSG00000053113	0.154461962672854	0.231692944009282	0.0144581508376465	0.0433744525129396	0.5978759287475	0.5978759287475

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IL-17 signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Nfkbia	ENSMUSG00000021025	0.455625354715448	0.636229315311352	0.636229315311352	0.636229315311352	0.399548817627028	0.636229315311352
Cxcl5	ENSMUSG00000029371	0.110625408309088	0.331876224927265	0.921139684946258	0.921139684946258	0.456692624137623	0.685038936206434
Cxcl1	ENSMUSG00000029380	0.703333998861023	0.703333998861023	0.635966700067775	0.703333998861023	0.0499430342679683	0.149829102803905
Ccl7	ENSMUSG00000035373	0.379206615039809	0.505169133438821	0.446194239410717	0.505169133438821	0.505169133438821	0.505169133438821
Ccl2	ENSMUSG00000035385	0.511097249598474	0.701310685803632	0.701310685803632	0.701310685803632	0.379996064861382	0.701310685803632
S100a9	ENSMUSG00000056071	0.004593575623324	0.013780726869972	0.199890020375968	0.199890020375968	0.134113174211452	0.199890020375968

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firebrick3

[1] “No significantly overrepresented pathways reported”

green4

Antigen processing and presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa1l	ENSMUSG00000007033	0.287873078401389	0.431809617602084	0.041737700208629	0.125213100625887	0.701310685803632	0.701310685803632
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Ciita	ENSMUSG00000022504	0.0171027900598199	0.0513083701794598	0.575824878403157	0.575824878403157	0.342405296020881	0.513607944031322
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Cd74	ENSMUSG00000024610	5.46967066778586e-05	0.000164090120033576	0.513665062682276	0.711034989117171	0.711034989117171	0.711034989117171
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Th17 cell differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Ahr	ENSMUSG00000019256	0.148115998140416	0.299349060054896	0.254414773803597	0.299349060054896	0.299349060054896	0.299349060054896
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Runx1	ENSMUSG00000022952	0.452880492349546	0.575824878403157	0.575824878403157	0.575824878403157	0.242231702094921	0.575824878403157
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Tgfbr2	ENSMUSG00000032440	0.11993617140438	0.359808514213139	0.643853282854191	0.643853282854191	0.295581119060361	0.443371678590541
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Graft-versus-host disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gzmb	ENSMUSG00000015437	0.0733738589968007	0.140462890655986	0.0936419271039908	0.140462890655986	0.926550375688041	0.926550375688041
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Th1 and Th2 cell differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Notch1	ENSMUSG00000026923	0.0334587898203823	0.100376369461147	0.852832278580641	0.852832278580641	0.577259514257969	0.852832278580641
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Maml2	ENSMUSG00000031925	0.0230207752632623	0.0690623257897868	0.513026869856283	0.513026869856283	0.255530331334266	0.383295497001398
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Hematopoietic cell lineage

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd33	ENSMUSG00000004609	0.455625354715449	0.455625354715449	0.216214347033995	0.324321520550992	0.00486041086018214	0.0145812325805464
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Cr1l	ENSMUSG00000016481	0.00477055016690543	0.0143116505007163	0.0588232673880149	0.0882349010820223	0.578113371816017	0.578113371816017
Itgb3	ENSMUSG00000020689	0.253294730253594	0.253294730253594	0.0109864933352154	0.0329594800056461	0.120850531362929	0.181275797044394
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Cd7	ENSMUSG00000025163	0.148772260628989	0.223158390943484	0.0964252305385472	0.223158390943484	0.852940894477647	0.852940894477647
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Siglech	ENSMUSG00000051504	0.209636747299872	0.598244634262948	0.852832278580641	0.852832278580641	0.398829756175299	0.598244634262948
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Type I diabetes mellitus

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gzmb	ENSMUSG00000015437	0.0733738589968007	0.140462890655986	0.0936419271039908	0.140462890655986	0.926550375688041	0.926550375688041
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
Gad1	ENSMUSG00000070880	0.0447373296833729	0.134211989050119	0.454258017332816	0.454258017332816	0.146471068967595	0.219706603451393
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Cytokine-cytokine receptor interaction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Edar	ENSMUSG00000003227	0.0575107614292586	0.172532284287776	0.511742979522636	0.511742979522636	0.2847237933399	0.42708569000985
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il18rap	ENSMUSG00000026068	0.000701972248021392	0.00210591674406418	0.0449262652924809	0.0449262652924809	0.00768144932639892	0.0115221739895984
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Cxcl9	ENSMUSG00000029417	0.0315593554855452	0.0946780664566356	0.0964252305385472	0.144637845807821	0.926550375688041	0.926550375688041
Ccr9	ENSMUSG00000029530	0.0413659913978561	0.124097974193568	0.443306001726868	0.443306001726868	0.144820068500793	0.21723010275119
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
Ccl17	ENSMUSG00000031780	0.000844544805216504	0.00253363441564951	0.0334587898203823	0.0501881847305735	0.45596561163947	0.45596561163947
Tgfbr2	ENSMUSG00000032440	0.11993617140438	0.359808514213139	0.643853282854191	0.643853282854191	0.295581119060361	0.443371678590541
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Cxcr6	ENSMUSG00000048521	5.17062302895136e-05	0.000155118690868541	0.0969812105731562	0.119631084167592	0.119631084167592	0.119631084167592
Ccr2	ENSMUSG00000049103	0.000387171985540247	0.00116151595662074	0.453225835454266	0.453225835454266	0.118409250205154	0.17761387530773
Xcr1	ENSMUSG00000060509	0.120545895661628	0.263623500370558	0.504833499869711	0.504833499869711	0.175749000247038	0.263623500370558
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Csf2rb	ENSMUSG00000071713	0.058823267388015	0.176469802164045	1	1	0.118714930081337	0.178072395122005
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594
Cntf	ENSMUSG00000079415	0.255530331334266	0.255530331334266	0.216214347033995	0.255530331334266	0.148772260628989	0.255530331334266

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Phagosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
M6pr	ENSMUSG00000007458	0.120850531362929	0.362551594088788	0.711854160331342	0.853372965654504	0.853372965654504	0.853372965654504
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Itgb3	ENSMUSG00000020689	0.253294730253594	0.253294730253594	0.0109864933352154	0.0329594800056461	0.120850531362929	0.181275797044394
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Msr1	ENSMUSG00000025044	0.298599969973533	0.770497594023414	0.853801250889739	0.853801250889739	0.513665062682276	0.770497594023414
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Colec11	ENSMUSG00000036655	0.252170177483002	0.756510532449007	0.512386180848416	0.768579271272624	0.781170242226513	0.781170242226513
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Fcgr3	ENSMUSG00000059498	0.0451153644990945	0.135346093497283	0.709375484777034	0.709375484777034	0.299349060054895	0.449023590082343
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Cell adhesion molecules

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Cd274	ENSMUSG00000016496	0.00486041086018214	0.0145812325805464	0.254787123615605	0.300095920620218	0.300095920620218	0.300095920620218
Pvrl3	ENSMUSG00000022656	0.00463747559282087	0.0139124267784626	0.511097249598474	0.511097249598474	0.444394285043028	0.511097249598474
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Cd226	ENSMUSG00000034028	0.180293335960318	0.270440003940477	0.0756145297453648	0.226843589236094	0.299349060054896	0.299349060054896
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Mag	ENSMUSG00000036634	0.147787500009832	0.221681250014749	0.0741204440774081	0.221681250014749	0.709166031912266	0.709166031912266
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Selplg	ENSMUSG00000048163	0.0197526720827851	0.0592580162483554	0.710416009055326	0.710416009055326	0.0763619660358786	0.114542949053818
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
Nlgn1	ENSMUSG00000063887	0.00261996864020088	0.00785990592060265	0.711034989117171	0.711034989117171	0.327972855903273	0.49195928385491
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Allograft rejection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gzmb	ENSMUSG00000015437	0.0733738589968007	0.140462890655986	0.0936419271039908	0.140462890655986	0.926550375688041	0.926550375688041
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Viral myocarditis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Abl2	ENSMUSG00000026596	0.0741204440774082	0.111180666116112	0.926550375688041	0.926550375688041	0.0334587898203823	0.100376369461147
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Leishmaniasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Cr1l	ENSMUSG00000016481	0.00477055016690543	0.0143116505007163	0.0588232673880149	0.0882349010820223	0.578113371816017	0.578113371816017
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Fcgr3	ENSMUSG00000059498	0.0451153644990945	0.135346093497283	0.709375484777034	0.709375484777034	0.299349060054895	0.449023590082343
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Rheumatoid arthritis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Viral protein interaction with cytokine and cytokine receptor

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Il18rap	ENSMUSG00000026068	0.000701972248021392	0.00210591674406418	0.0449262652924809	0.0449262652924809	0.00768144932639892	0.0115221739895984
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Cxcl9	ENSMUSG00000029417	0.0315593554855452	0.0946780664566356	0.0964252305385472	0.144637845807821	0.926550375688041	0.926550375688041
Ccr9	ENSMUSG00000029530	0.0413659913978561	0.124097974193568	0.443306001726868	0.443306001726868	0.144820068500793	0.21723010275119
Ccl17	ENSMUSG00000031780	0.000844544805216504	0.00253363441564951	0.0334587898203823	0.0501881847305735	0.45596561163947	0.45596561163947
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Ccr2	ENSMUSG00000049103	0.000387171985540247	0.00116151595662074	0.453225835454266	0.453225835454266	0.118409250205154	0.17761387530773
Xcr1	ENSMUSG00000060509	0.120545895661628	0.263623500370558	0.504833499869711	0.504833499869711	0.175749000247038	0.263623500370558
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594

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Autoimmune thyroid disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gzmb	ENSMUSG00000015437	0.0733738589968007	0.140462890655986	0.0936419271039908	0.140462890655986	0.926550375688041	0.926550375688041
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Inflammatory bowel disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Il18rap	ENSMUSG00000026068	0.000701972248021392	0.00210591674406418	0.0449262652924809	0.0449262652924809	0.00768144932639892	0.0115221739895984
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Tuberculosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Cr1l	ENSMUSG00000016481	0.00477055016690543	0.0143116505007163	0.0588232673880149	0.0882349010820223	0.578113371816017	0.578113371816017
Ciita	ENSMUSG00000022504	0.0171027900598199	0.0513083701794598	0.575824878403157	0.575824878403157	0.342405296020881	0.513607944031322
Cd74	ENSMUSG00000024610	5.46967066778586e-05	0.000164090120033576	0.513665062682276	0.711034989117171	0.711034989117171	0.711034989117171
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Itgax	ENSMUSG00000030789	0.0331400397096515	0.0994201191289544	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Fcgr3	ENSMUSG00000059498	0.0451153644990945	0.135346093497283	0.709375484777034	0.709375484777034	0.299349060054895	0.449023590082343
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Toxoplasmosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa1l	ENSMUSG00000007033	0.287873078401389	0.431809617602084	0.041737700208629	0.125213100625887	0.701310685803632	0.701310685803632
Ciita	ENSMUSG00000022504	0.0171027900598199	0.0513083701794598	0.575824878403157	0.575824878403157	0.342405296020881	0.513607944031322
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Irgm1	ENSMUSG00000046879	0.00276975149305653	0.00830925447916959	0.0168921052924602	0.0253381579386902	0.711240436189781	0.711240436189781
Tlr11	ENSMUSG00000051969	0.145811394942709	0.218717092414064	0.711445446052875	0.711445446052875	0.11810342389482	0.218717092414064
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
Irgm2	ENSMUSG00000069874	0.000164597779190222	0.000493793337570667	0.0756145297453647	0.113421794618047	0.78180291566155	0.78180291566155
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
Igtp	ENSMUSG00000078853	0.000394209637342662	0.00118262891202798	0.0756145297453646	0.113421794618047	0.926550375688041	0.926550375688041
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Human T-cell leukemia virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Tgfbr2	ENSMUSG00000032440	0.11993617140438	0.359808514213139	0.643853282854191	0.643853282854191	0.295581119060361	0.443371678590541
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Epstein-Barr virus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Staphylococcus aureus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Selplg	ENSMUSG00000048163	0.0197526720827851	0.0592580162483554	0.710416009055326	0.710416009055326	0.0763619660358786	0.114542949053818
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Fcgr3	ENSMUSG00000059498	0.0451153644990945	0.135346093497283	0.709375484777034	0.709375484777034	0.299349060054895	0.449023590082343
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Asthma

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Chemokine signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Fgr	ENSMUSG00000028874	0.0449262652924809	0.0673893979387214	0.392243127063687	0.392243127063687	0.0443599545252853	0.0673893979387214
Cxcl9	ENSMUSG00000029417	0.0315593554855452	0.0946780664566356	0.0964252305385472	0.144637845807821	0.926550375688041	0.926550375688041
Ccr9	ENSMUSG00000029530	0.0413659913978561	0.124097974193568	0.443306001726868	0.443306001726868	0.144820068500793	0.21723010275119
Ccl17	ENSMUSG00000031780	0.000844544805216504	0.00253363441564951	0.0334587898203823	0.0501881847305735	0.45596561163947	0.45596561163947
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Cxcr6	ENSMUSG00000048521	5.17062302895136e-05	0.000155118690868541	0.0969812105731562	0.119631084167592	0.119631084167592	0.119631084167592
Ccr2	ENSMUSG00000049103	0.000387171985540247	0.00116151595662074	0.453225835454266	0.453225835454266	0.118409250205154	0.17761387530773
Xcr1	ENSMUSG00000060509	0.120545895661628	0.263623500370558	0.504833499869711	0.504833499869711	0.175749000247038	0.263623500370558
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594

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Primary immunodeficiency

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ciita	ENSMUSG00000022504	0.0171027900598199	0.0513083701794598	0.575824878403157	0.575824878403157	0.342405296020881	0.513607944031322
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318

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Natural killer cell mediated cytotoxicity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Gzmb	ENSMUSG00000015437	0.0733738589968007	0.140462890655986	0.0936419271039908	0.140462890655986	0.926550375688041	0.926550375688041
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Hcst	ENSMUSG00000064109	0.00477055016690543	0.0143116505007163	0.255530331334266	0.383295497001398	0.853801250889739	0.853801250889739
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103

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Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Zim1	ENSMUSG00000002266	0.00118646104989536	0.00355938314968607	0.133436131064877	0.200154196597315	0.37032580521798	0.37032580521798
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Itgb3	ENSMUSG00000020689	0.253294730253594	0.253294730253594	0.0109864933352154	0.0329594800056461	0.120850531362929	0.181275797044394
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Cd74	ENSMUSG00000024610	5.46967066778586e-05	0.000164090120033576	0.513665062682276	0.711034989117171	0.711034989117171	0.711034989117171
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Pilra	ENSMUSG00000046245	0.000161017133377609	0.000483051400132826	0.113190884633071	0.169786326949606	0.398469281729516	0.398469281729516
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
Zfp28	ENSMUSG00000062861	0.214037080764326	0.642111242292977	1	1	0.711650020253571	1
Pilrb2	ENSMUSG00000066682	0.0243249029874197	0.0729747089622591	0.712057867818062	0.712057867818062	0.391498225369151	0.587247338053727
Pilrb1	ENSMUSG00000066684	0.0588232673880149	0.114542949053818	0.180293335960318	0.180293335960318	0.0763619660358787	0.114542949053818
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Intestinal immune network for IgA production

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccr9	ENSMUSG00000029530	0.0413659913978561	0.124097974193568	0.443306001726868	0.443306001726868	0.144820068500793	0.21723010275119
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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TNF signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mlkl	ENSMUSG00000012519	0.0321889748775514	0.0482834623163271	0.0241933715424143	0.0482834623163271	0.286303237509397	0.286303237509397
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Irf1	ENSMUSG00000018899	0.00283103937188885	0.00849311811566654	0.113190884633071	0.169786326949606	0.852504981253341	0.852504981253341
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Ifi47	ENSMUSG00000078920	0.000394209637342662	0.00118262891202799	0.395928178642446	0.395928178642446	0.214764523938594	0.322146785907891

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Pertussis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Irf1	ENSMUSG00000018899	0.00283103937188885	0.00849311811566654	0.113190884633071	0.169786326949606	0.852504981253341	0.852504981253341
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
Irf8	ENSMUSG00000041515	0.000819575681707138	0.00245872704512142	0.711854160331342	0.711854160331342	0.711034989117171	0.711854160331342
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891

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Chagas disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Tgfbr2	ENSMUSG00000032440	0.11993617140438	0.359808514213139	0.643853282854191	0.643853282854191	0.295581119060361	0.443371678590541
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028

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Human immunodeficiency virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Samhd1	ENSMUSG00000027639	0.288654423610209	0.432981635415313	0.778911768167544	0.778911768167544	0.174692232033629	0.432981635415313
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594

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Osteoclast differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Itgb3	ENSMUSG00000020689	0.253294730253594	0.253294730253594	0.0109864933352154	0.0329594800056461	0.120850531362929	0.181275797044394
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
Tgfbr2	ENSMUSG00000032440	0.11993617140438	0.359808514213139	0.643853282854191	0.643853282854191	0.295581119060361	0.443371678590541
Pirb	ENSMUSG00000058818	0.0967032506702099	0.26625532344024	0.853587578053106	0.853587578053106	0.17750354896016	0.26625532344024
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
Fcgr3	ENSMUSG00000059498	0.0451153644990945	0.135346093497283	0.709375484777034	0.709375484777034	0.299349060054895	0.449023590082343

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Influenza A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ciita	ENSMUSG00000022504	0.0171027900598199	0.0513083701794598	0.575824878403157	0.575824878403157	0.342405296020881	0.513607944031322
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tpsb2	ENSMUSG00000033825	0.0741204440774084	0.144220726677154	0.096147151118103	0.144220726677154	0.926387617028817	0.926387617028817
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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Human cytomegalovirus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Itgb3	ENSMUSG00000020689	0.253294730253594	0.253294730253594	0.0109864933352154	0.0329594800056461	0.120850531362929	0.181275797044394
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
H2-D1	ENSMUSG00000073411	0.00159435459956481	0.00478306379869443	0.851954599472143	0.851954599472143	0.509144723230069	0.763717084845103
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594

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Toll-like receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Cxcl9	ENSMUSG00000029417	0.0315593554855452	0.0946780664566356	0.0964252305385472	0.144637845807821	0.926550375688041	0.926550375688041
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282

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Systemic lupus erythematosus

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hist1h2bc	ENSMUSG00000018102	0.00719286546902974	0.0073134885581712	0.0073134885581712	0.0073134885581712	0.00270924971713393	0.0073134885581712
H2-Aa	ENSMUSG00000036594	0.000844544805216505	0.00253363441564951	0.148115998140416	0.216214347033995	0.216214347033995	0.216214347033995
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
H2-DMa	ENSMUSG00000037649	3.51112183354995e-05	0.000105333655006499	0.174692232033629	0.262038348050444	0.708534948098331	0.708534948098331
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
H2-Eb1	ENSMUSG00000060586	5.17062302895138e-05	0.000155118690868541	0.926333123228344	0.926333123228344	0.213307944885796	0.319961917328694
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
H2-Ab1	ENSMUSG00000073421	0.000164597779190222	0.000493793337570665	0.853480389728993	0.853480389728993	0.78148726569172	0.853480389728993
H2-DMb1	ENSMUSG00000079547	5.46967066778587e-05	0.000164090120033576	0.0964252305385472	0.144637845807821	0.342026805366747	0.342026805366747

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JAK-STAT signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Socs7	ENSMUSG00000038485	0.0763619660358785	0.229085898107636	0.576973746230334	0.576973746230334	0.455625354715449	0.576973746230334
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Csf2rb	ENSMUSG00000071713	0.058823267388015	0.176469802164045	1	1	0.118714930081337	0.178072395122005
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569
Cntf	ENSMUSG00000079415	0.255530331334266	0.255530331334266	0.216214347033995	0.255530331334266	0.148772260628989	0.255530331334266

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PD-L1 expression and PD-1 checkpoint pathway in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd274	ENSMUSG00000016496	0.00486041086018214	0.0145812325805464	0.254787123615605	0.300095920620218	0.300095920620218	0.300095920620218
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Batf	ENSMUSG00000034266	0.0145470016597441	0.0436410049792323	0.45253450475104	0.45253450475104	0.0581665372625692	0.0872498058938538
Batf2	ENSMUSG00000039699	0.00442026986621116	0.0132608095986335	0.0303111090728679	0.0454666636093018	0.576973746230334	0.576973746230334

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Complement and coagulation cascades

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb2	ENSMUSG00000000290	0.144157978128026	0.324321520550992	0.852504981253341	0.852504981253341	0.216214347033995	0.324321520550992
Cr1l	ENSMUSG00000016481	0.00477055016690543	0.0143116505007163	0.0588232673880149	0.0882349010820223	0.578113371816017	0.578113371816017
Procr	ENSMUSG00000027611	0.000844544805216504	0.00253363441564951	0.346527959006435	0.519791938509652	0.643853282854191	0.643853282854191
Itgax	ENSMUSG00000030789	0.0331400397096515	0.0994201191289544	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891

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Measles

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Hspa1l	ENSMUSG00000007033	0.287873078401389	0.431809617602084	0.041737700208629	0.125213100625887	0.701310685803632	0.701310685803632
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Fas	ENSMUSG00000024778	0.121155015244363	0.181732522866545	0.0953125666339398	0.181732522866545	1	1
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tlr2	ENSMUSG00000027995	0.00689577866107721	0.0206873359832316	0.215127611919161	0.322691417878742	1	1
Jak3	ENSMUSG00000031805	0.177153312234059	0.211844580334808	0.211844580334808	0.211844580334808	0.146800541856249	0.211844580334808
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441

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Cytosolic DNA-sensing pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Zbp1	ENSMUSG00000027514	0.00153425095635555	0.00460275286906665	0.00743512899358789	0.0111526934903818	0.642366752097095	0.642366752097095
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282

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NF-kappa B signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Edar	ENSMUSG00000003227	0.0575107614292586	0.172532284287776	0.511742979522636	0.511742979522636	0.2847237933399	0.42708569000985
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Parp1	ENSMUSG00000026496	0.016163073542596	0.0484892206277881	0.348008842235184	0.397021051130447	0.397021051130447	0.397021051130447
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477

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NOD-like receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mefv	ENSMUSG00000022534	0.255530331334266	0.383295497001398	0.853587578053106	0.853587578053106	0.0671691953892782	0.201507586167835
Sharpin	ENSMUSG00000022552	0.0230207752632623	0.0690623257897868	0.711854160331342	0.711854160331342	0.177153312234059	0.265729968351089
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Gbp3	ENSMUSG00000028268	0.0328221470541517	0.098466441162455	1	1	0.295581119060361	0.443371678590541
Gbp2	ENSMUSG00000028270	0.0101222094973346	0.0303666284920038	0.141500034183268	0.212250051274902	0.710208797518812	0.710208797518812
P2rx7	ENSMUSG00000029468	0.0331400397096515	0.0994201191289544	0.782117202022501	0.782117202022501	0.397384062266614	0.596076093399921
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Gbp7	ENSMUSG00000040253	0.0334587898203823	0.100376369461147	0.392985378348026	0.392985378348026	0.388491809581663	0.392985378348026
Gbp5	ENSMUSG00000040264	0.058823267388015	0.176469802164045	0.853480389728993	0.853480389728993	0.641867098978198	0.853480389728993
Ifi204	ENSMUSG00000073489	0.0936419271039908	0.280925781311972	0.454600801949285	0.681901202923927	0.708323672944427	0.708323672944427

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Ether lipid metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pla2g7	ENSMUSG00000023913	0.0583853430099098	0.0888924005190769	0.0592616003460512	0.0888924005190769	0.148115998140416	0.148115998140416
Lpcat2	ENSMUSG00000033192	0.120850531362929	0.362551594088787	0.853801250889739	0.853801250889739	0.578113371816017	0.853801250889739
Pla2g2d	ENSMUSG00000041202	0.0756145297453648	0.113421794618047	0.0331400397096514	0.0994201191289543	0.148115998140416	0.148115998140416
Pld4	ENSMUSG00000052160	0.0217422311863571	0.0652266935590713	0.391498225369152	0.587247338053727	0.711240436189781	0.711240436189781
Pla2g16	ENSMUSG00000060675	0.00283103937188883	0.00849311811566648	1	1	0.852832278580641	1

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C-type lectin receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf1	ENSMUSG00000018899	0.00283103937188885	0.00849311811566654	0.113190884633071	0.169786326949606	0.852504981253341	0.852504981253341
Clec4n	ENSMUSG00000023349	0.0199974585097313	0.0599923755291938	0.455625354715449	0.683438032073173	1	1
Stat1	ENSMUSG00000026104	0.00463747559282087	0.0139124267784626	0.0953125666339397	0.142968849950909	0.853801250889739	0.853801250889739
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Ccl17	ENSMUSG00000031780	0.000844544805216504	0.00253363441564951	0.0334587898203823	0.0501881847305735	0.45596561163947	0.45596561163947
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777

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Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gm2a	ENSMUSG00000000594	0.010906560635693	0.0327196819070789	0.395928178642446	0.395928178642446	0.120545895661628	0.180818843492441
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Edar	ENSMUSG00000003227	0.0575107614292586	0.172532284287776	0.511742979522636	0.511742979522636	0.2847237933399	0.42708569000985
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Cd33	ENSMUSG00000004609	0.455625354715449	0.455625354715449	0.216214347033995	0.324321520550992	0.00486041086018214	0.0145812325805464
Klhl3	ENSMUSG00000014164	0.346156228791382	0.397746436553874	0.397746436553874	0.397746436553874	0.213672724643677	0.397746436553874
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Cd274	ENSMUSG00000016496	0.00486041086018214	0.0145812325805464	0.254787123615605	0.300095920620218	0.300095920620218	0.300095920620218
Cd68	ENSMUSG00000018774	0.12085053136293	0.362551594088789	0.255530331334266	0.383295497001398	0.577829325134931	0.577829325134931
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Ube2o	ENSMUSG00000020802	0.0761127945805735	0.228338383741721	0.568427079091759	0.568427079091759	0.395928178642446	0.568427079091759
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Mefv	ENSMUSG00000022534	0.255530331334266	0.383295497001398	0.853587578053106	0.853587578053106	0.0671691953892782	0.201507586167835
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Clec4n	ENSMUSG00000023349	0.0199974585097313	0.0599923755291938	0.455625354715449	0.683438032073173	1	1
Mmp25	ENSMUSG00000023903	0.058823267388015	0.0882349010820225	0.643853282854191	0.643853282854191	0.000844544805216504	0.00253363441564951
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Cd74	ENSMUSG00000024610	5.46967066778586e-05	0.000164090120033576	0.513665062682276	0.711034989117171	0.711034989117171	0.711034989117171
Rnf41	ENSMUSG00000025373	0.508817043656047	0.508817043656047	0.398469281729516	0.508817043656047	0.0751163767602349	0.225349130280705
Ifitm1	ENSMUSG00000025491	0.058823267388015	0.175777610154895	0.926658283600152	0.926658283600152	0.117185073436597	0.175777610154895
Hk3	ENSMUSG00000025877	0.0116356061791785	0.0349068185375355	0.216214347033995	0.324321520550992	0.397384062266614	0.397384062266614
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Dsn1	ENSMUSG00000027635	0.118714930081337	0.178072395122005	0.179945789077372	0.179945789077372	0.000844544805216505	0.00253363441564951
Sla2	ENSMUSG00000027636	0.0763619660358786	0.229085898107636	0.255530331334266	0.255530331334266	0.212942741031873	0.255530331334266
Dapp1	ENSMUSG00000028159	0.179945789077371	0.269918683616057	0.0763619660358786	0.229085898107636	0.346899083932133	0.346899083932133
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Fgr	ENSMUSG00000028874	0.0449262652924809	0.0673893979387214	0.392243127063687	0.392243127063687	0.0443599545252853	0.0673893979387214
Slc15a4	ENSMUSG00000029416	0.0964252305385472	0.17761387530773	0.177853449259986	0.177853449259986	0.118409250205154	0.17761387530773
P2rx7	ENSMUSG00000029468	0.0331400397096515	0.0994201191289544	0.782117202022501	0.782117202022501	0.397384062266614	0.596076093399921
Herc6	ENSMUSG00000029798	0.0236697127745139	0.0355045691617709	0.0116356061791785	0.0349068185375355	0.577829325134931	0.577829325134931
Lag3	ENSMUSG00000030124	5.46967066778586e-05	0.000164090120033576	0.514934023620345	0.514934023620345	0.000387171985540247	0.000580757978310371
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Itgax	ENSMUSG00000030789	0.0331400397096515	0.0994201191289544	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
Armc8	ENSMUSG00000032468	0.455625354715449	0.455625354715449	0.450444934184774	0.455625354715449	0.300095920620218	0.455625354715449
Uba7	ENSMUSG00000032596	0.0113901882503033	0.0341705647509098	0.78148726569172	0.78148726569172	0.110721602500731	0.166082403751097
Cd226	ENSMUSG00000034028	0.180293335960318	0.270440003940477	0.0756145297453648	0.226843589236094	0.299349060054896	0.299349060054896
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Rapgef1	ENSMUSG00000039844	0.0152452683068771	0.0457358049206313	0.577259514257969	0.643359829732651	0.643359829732651	0.643359829732651
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Pilra	ENSMUSG00000046245	0.000161017133377609	0.000483051400132826	0.113190884633071	0.169786326949606	0.398469281729516	0.398469281729516
Siglech	ENSMUSG00000051504	0.209636747299872	0.598244634262948	0.852832278580641	0.852832278580641	0.398829756175299	0.598244634262948
Pld4	ENSMUSG00000052160	0.0217422311863571	0.0652266935590713	0.391498225369152	0.587247338053727	0.711240436189781	0.711240436189781
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
Nfam1	ENSMUSG00000058099	0.0312459040565944	0.0937377121697832	0.454600801949285	0.578113371816017	0.578113371816017	0.578113371816017
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Pirb	ENSMUSG00000058818	0.0967032506702099	0.26625532344024	0.853587578053106	0.853587578053106	0.17750354896016	0.26625532344024
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
Hcst	ENSMUSG00000064109	0.00477055016690543	0.0143116505007163	0.255530331334266	0.383295497001398	0.853801250889739	0.853801250889739
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Rnf213	ENSMUSG00000070327	0.00153425095635555	0.00460275286906664	0.0964252305385472	0.144637845807821	0.399548817627028	0.399548817627028
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
Ifi204	ENSMUSG00000073489	0.0936419271039908	0.280925781311972	0.454600801949285	0.681901202923927	0.708323672944427	0.708323672944427
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777
Cntf	ENSMUSG00000079415	0.255530331334266	0.255530331334266	0.216214347033995	0.255530331334266	0.148772260628989	0.255530331334266

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Chemokine receptors bind chemokines

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ccl3	ENSMUSG00000000982	0.21549027811633	0.323235417174495	0.782117202022501	0.782117202022501	0.0583853430099098	0.175156029029729
Ccl4	ENSMUSG00000018930	0.000157492167861666	0.000472476503584999	0.058823267388015	0.0882349010820225	0.346899083932133	0.346899083932133
Cxcl9	ENSMUSG00000029417	0.0315593554855452	0.0946780664566356	0.0964252305385472	0.144637845807821	0.926550375688041	0.926550375688041
Ccr9	ENSMUSG00000029530	0.0413659913978561	0.124097974193568	0.443306001726868	0.443306001726868	0.144820068500793	0.21723010275119
Ccl17	ENSMUSG00000031780	0.000844544805216504	0.00253363441564951	0.0334587898203823	0.0501881847305735	0.45596561163947	0.45596561163947
Cxcl10	ENSMUSG00000034855	0.000346741672927651	0.00104022501878295	0.572616808177226	0.711034989117171	0.711034989117171	0.711034989117171
Ccl5	ENSMUSG00000035042	0.00719286546902974	0.0215785964070892	0.148772260628989	0.223158390943484	0.926003599371282	0.926003599371282
Cxcr6	ENSMUSG00000048521	5.17062302895136e-05	0.000155118690868541	0.0969812105731562	0.119631084167592	0.119631084167592	0.119631084167592
Xcr1	ENSMUSG00000060509	0.120545895661628	0.263623500370558	0.504833499869711	0.504833499869711	0.175749000247038	0.263623500370558
Ccr5	ENSMUSG00000079227	0.0434194723707708	0.0662572764365975	0.0441715176243983	0.0662572764365975	0.214764523938594	0.214764523938594

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Dectin-2 family

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Clec4n	ENSMUSG00000023349	0.0199974585097313	0.0599923755291938	0.455625354715449	0.683438032073173	1	1
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474

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Cytokine Signaling in Immune system

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Edar	ENSMUSG00000003227	0.0575107614292586	0.172532284287776	0.511742979522636	0.511742979522636	0.2847237933399	0.42708569000985
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Sla2	ENSMUSG00000027636	0.0763619660358786	0.229085898107636	0.255530331334266	0.255530331334266	0.212942741031873	0.255530331334266
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Tnfsf13b	ENSMUSG00000031497	0.852940894477647	0.852940894477647	0.781170242226513	0.852940894477647	0.0579478375430677	0.173843512629203
Uba7	ENSMUSG00000032596	0.0113901882503033	0.0341705647509098	0.78148726569172	0.78148726569172	0.110721602500731	0.166082403751097
Rapgef1	ENSMUSG00000039844	0.0152452683068771	0.0457358049206313	0.577259514257969	0.643359829732651	0.643359829732651	0.643359829732651
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569
Cntf	ENSMUSG00000079415	0.255530331334266	0.255530331334266	0.216214347033995	0.255530331334266	0.148772260628989	0.255530331334266

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ER-Phagosome pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Signaling by Interleukins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il12rb1	ENSMUSG00000000791	0.0236697127745139	0.0710091383235417	0.398108175780842	0.597162263671263	0.852065168704833	0.852065168704833
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Il1r2	ENSMUSG00000026073	0.00463747559282087	0.0139124267784626	0.578113371816017	0.578113371816017	0.400265374208515	0.578113371816017
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Csf3r	ENSMUSG00000028859	0.0947558980989551	0.284267694296865	0.643853282854191	0.643853282854191	0.293293089483362	0.439939634225043
Il4ra	ENSMUSG00000030748	0.0325051220296005	0.0975153660888013	0.568427079091759	0.568427079091759	0.11595859961889	0.173937899428335
Rapgef1	ENSMUSG00000039844	0.0152452683068771	0.0457358049206313	0.577259514257969	0.643359829732651	0.643359829732651	0.643359829732651
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569
Cntf	ENSMUSG00000079415	0.255530331334266	0.255530331334266	0.216214347033995	0.255530331334266	0.148772260628989	0.255530331334266

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Interleukin-3, Interleukin-5 and GM-CSF signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Rapgef1	ENSMUSG00000039844	0.0152452683068771	0.0457358049206313	0.577259514257969	0.643359829732651	0.643359829732651	0.643359829732651
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441
Csf2rb2	ENSMUSG00000071714	0.044737329683373	0.134211989050119	0.400265374208515	0.400265374208515	0.11993617140438	0.179904257106569

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DAP12 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd33	ENSMUSG00000004609	0.455625354715449	0.455625354715449	0.216214347033995	0.324321520550992	0.00486041086018214	0.0145812325805464
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Ifitm1	ENSMUSG00000025491	0.058823267388015	0.175777610154895	0.926658283600152	0.926658283600152	0.117185073436597	0.175777610154895
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Cd226	ENSMUSG00000034028	0.180293335960318	0.270440003940477	0.0756145297453648	0.226843589236094	0.299349060054896	0.299349060054896
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Pilra	ENSMUSG00000046245	0.000161017133377609	0.000483051400132826	0.113190884633071	0.169786326949606	0.398469281729516	0.398469281729516
Siglech	ENSMUSG00000051504	0.209636747299872	0.598244634262948	0.852832278580641	0.852832278580641	0.398829756175299	0.598244634262948
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
Hcst	ENSMUSG00000064109	0.00477055016690543	0.0143116505007163	0.255530331334266	0.383295497001398	0.853801250889739	0.853801250889739
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Antigen Presentation: Folding, assembly and peptide loading of class I MHC

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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DAP12 interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Antigen processing-Cross presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Adaptive Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd33	ENSMUSG00000004609	0.455625354715449	0.455625354715449	0.216214347033995	0.324321520550992	0.00486041086018214	0.0145812325805464
Klhl3	ENSMUSG00000014164	0.346156228791382	0.397746436553874	0.397746436553874	0.397746436553874	0.213672724643677	0.397746436553874
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Cd274	ENSMUSG00000016496	0.00486041086018214	0.0145812325805464	0.254787123615605	0.300095920620218	0.300095920620218	0.300095920620218
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Ube2o	ENSMUSG00000020802	0.0761127945805735	0.228338383741721	0.568427079091759	0.568427079091759	0.395928178642446	0.568427079091759
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Tap2	ENSMUSG00000024339	0.000844544805216502	0.00253363441564951	0.577829325134931	0.577829325134931	0.299349060054895	0.449023590082343
Cd74	ENSMUSG00000024610	5.46967066778586e-05	0.000164090120033576	0.513665062682276	0.711034989117171	0.711034989117171	0.711034989117171
Rnf41	ENSMUSG00000025373	0.508817043656047	0.508817043656047	0.398469281729516	0.508817043656047	0.0751163767602349	0.225349130280705
Ifitm1	ENSMUSG00000025491	0.058823267388015	0.175777610154895	0.926658283600152	0.926658283600152	0.117185073436597	0.175777610154895
Zap70	ENSMUSG00000026117	0.0751163767602349	0.225349130280705	0.576687400573867	0.576687400573867	0.215127611919161	0.322691417878742
Dapp1	ENSMUSG00000028159	0.179945789077371	0.269918683616057	0.0763619660358786	0.229085898107636	0.346899083932133	0.346899083932133
Herc6	ENSMUSG00000029798	0.0236697127745139	0.0355045691617709	0.0116356061791785	0.0349068185375355	0.577829325134931	0.577829325134931
Lag3	ENSMUSG00000030124	5.46967066778586e-05	0.000164090120033576	0.514934023620345	0.514934023620345	0.000387171985540247	0.000580757978310371
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Uba7	ENSMUSG00000032596	0.0113901882503033	0.0341705647509098	0.78148726569172	0.78148726569172	0.110721602500731	0.166082403751097
Cd226	ENSMUSG00000034028	0.180293335960318	0.270440003940477	0.0756145297453648	0.226843589236094	0.299349060054896	0.299349060054896
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
Tap1	ENSMUSG00000037321	5.78125466309114e-05	0.000173437639892734	0.643359829732651	0.643359829732651	0.121155015244363	0.181732522866545
Icam1	ENSMUSG00000037405	0.0329809855655598	0.0989429566966793	1	1	0.146471068967596	0.219706603451393
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Pilra	ENSMUSG00000046245	0.000161017133377609	0.000483051400132826	0.113190884633071	0.169786326949606	0.398469281729516	0.398469281729516
Siglech	ENSMUSG00000051504	0.209636747299872	0.598244634262948	0.852832278580641	0.852832278580641	0.398829756175299	0.598244634262948
Cd8a	ENSMUSG00000053977	0.044737329683373	0.134211989050119	0.0969812105731562	0.145471815859734	0.180293335960318	0.180293335960318
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
Hcst	ENSMUSG00000064109	0.00477055016690543	0.0143116505007163	0.255530331334266	0.383295497001398	0.853801250889739	0.853801250889739
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
Rnf213	ENSMUSG00000070327	0.00153425095635555	0.00460275286906664	0.0964252305385472	0.144637845807821	0.399548817627028	0.399548817627028

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Endosomal/Vacuolar pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283

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Innate Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gm2a	ENSMUSG00000000594	0.010906560635693	0.0327196819070789	0.395928178642446	0.395928178642446	0.120545895661628	0.180818843492441
H2-M3	ENSMUSG00000016206	0.0753654386865988	0.113048158029898	0.703556284613037	0.703556284613037	0.0585643824160222	0.113048158029898
Cd68	ENSMUSG00000018774	0.12085053136293	0.362551594088789	0.255530331334266	0.383295497001398	0.577829325134931	0.577829325134931
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Fos	ENSMUSG00000021250	0.00481536616919077	0.0144460985075723	0.453225835454266	0.453225835454266	0.453225835454266	0.453225835454266
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Mefv	ENSMUSG00000022534	0.255530331334266	0.383295497001398	0.853587578053106	0.853587578053106	0.0671691953892782	0.201507586167835
Cd4	ENSMUSG00000023274	0.044737329683373	0.134211989050119	0.576973746230334	0.576973746230334	0.11993617140438	0.179904257106569
Clec4n	ENSMUSG00000023349	0.0199974585097313	0.0599923755291938	0.455625354715449	0.683438032073173	1	1
Mmp25	ENSMUSG00000023903	0.058823267388015	0.0882349010820225	0.643853282854191	0.643853282854191	0.000844544805216504	0.00253363441564951
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Tmem173	ENSMUSG00000024349	0.0566379395854603	0.169913818756381	0.119631084167591	0.17433930265919	0.17433930265919	0.17433930265919
Hk3	ENSMUSG00000025877	0.0116356061791785	0.0349068185375355	0.216214347033995	0.324321520550992	0.397384062266614	0.397384062266614
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Dsn1	ENSMUSG00000027635	0.118714930081337	0.178072395122005	0.179945789077372	0.179945789077372	0.000844544805216505	0.00253363441564951
Tnfrsf1b	ENSMUSG00000028599	0.00280029710610443	0.00840089131831328	0.781645261743309	0.781645261743309	0.215127611919161	0.322691417878741
Fgr	ENSMUSG00000028874	0.0449262652924809	0.0673893979387214	0.392243127063687	0.392243127063687	0.0443599545252853	0.0673893979387214
Slc15a4	ENSMUSG00000029416	0.0964252305385472	0.17761387530773	0.177853449259986	0.177853449259986	0.118409250205154	0.17761387530773
P2rx7	ENSMUSG00000029468	0.0331400397096515	0.0994201191289544	0.782117202022501	0.782117202022501	0.397384062266614	0.596076093399921
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Klrd1	ENSMUSG00000030165	0.00247508107184991	0.00742524321554973	0.514934023620345	0.772401035430517	0.853694531487825	0.853694531487825
Tyrobp	ENSMUSG00000030579	0.0241933715424142	0.0725801146272426	0.78148726569172	0.78148726569172	0.45596561163947	0.683948417459205
Itgax	ENSMUSG00000030789	0.0331400397096515	0.0994201191289544	0.254414773803597	0.254414773803597	0.252920381501207	0.254414773803597
Armc8	ENSMUSG00000032468	0.455625354715449	0.455625354715449	0.450444934184774	0.455625354715449	0.300095920620218	0.455625354715449
H2-Q4	ENSMUSG00000035929	0.0162664168407234	0.0487992505221701	0.926658283600152	0.926658283600152	0.454600801949285	0.681901202923927
C1qa	ENSMUSG00000036887	0.000844544805216504	0.00253363441564951	0.642366752097095	0.642366752097095	0.398108175780842	0.597162263671263
C1qc	ENSMUSG00000036896	0.000387171985540247	0.00116151595662074	0.0443599545252852	0.0665399317879278	0.299349060054895	0.299349060054895
C1qb	ENSMUSG00000036905	0.000387171985540247	0.00116151595662074	0.0969812105731562	0.145471815859734	0.399548817627028	0.399548817627028
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Pld4	ENSMUSG00000052160	0.0217422311863571	0.0652266935590713	0.391498225369152	0.587247338053727	0.711240436189781	0.711240436189781
Nfam1	ENSMUSG00000058099	0.0312459040565944	0.0937377121697832	0.454600801949285	0.578113371816017	0.578113371816017	0.578113371816017
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Pirb	ENSMUSG00000058818	0.0967032506702099	0.26625532344024	0.853587578053106	0.853587578053106	0.17750354896016	0.26625532344024
Fcgr4	ENSMUSG00000059089	0.00477055016690543	0.0143116505007163	0.926003599371282	0.926003599371282	0.7802108304765	0.926003599371282
H2-Q7	ENSMUSG00000060550	0.0441715176243983	0.132514552873195	0.924405146515181	0.924405146515181	0.384672302267076	0.577008453400614
B2m	ENSMUSG00000060802	0.395928178642446	0.593892267963669	0.113190884633071	0.339572653899213	0.9255572759333	0.9255572759333
H2-Q10	ENSMUSG00000067235	0.117185073436597	0.175777610154895	0.096425230538547	0.175777610154895	0.513026869856283	0.513026869856283
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
Ifi204	ENSMUSG00000073489	0.0936419271039908	0.280925781311972	0.454600801949285	0.681901202923927	0.708323672944427	0.708323672944427
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777

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Interleukin-2 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441

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Post-translational protein phosphorylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoe	ENSMUSG00000002985	0.01710279005982	0.0513083701794599	0.120545895661628	0.180818843492441	0.454942951775341	0.454942951775341
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Apol7c	ENSMUSG00000044309	0.0171027900598199	0.0513083701794597	0.118714930081337	0.118714930081337	0.0969812105731562	0.118714930081337
Apol10b	ENSMUSG00000050014	0.0110666956860337	0.0332000870581011	1	1	0.853372965654504	1
Apol10a	ENSMUSG00000050982	0.000771096743445034	0.0023132902303351	0.178901132102685	0.268351698154027	0.782117202022501	0.782117202022501
Serpina10	ENSMUSG00000061947	0.0232795908282423	0.0349193862423635	0.0116356061791785	0.0349068185375355	0.0701431284016185	0.0701431284016185
Apol7e	ENSMUSG00000071716	0.0449262652924809	0.134778795877443	0.509144723230069	0.639337105615665	0.639337105615665	0.639337105615665
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
Apol11b	ENSMUSG00000091694	0.0969812105731563	0.290943631719469	0.57113445032749	0.852504981253341	0.852504981253341	0.852504981253341

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Platelet Adhesion to exposed collagen

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474

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C-type lectin receptors (CLRs)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Psme1	ENSMUSG00000022216	0.000394209637342661	0.00118262891202798	0.782117202022501	1	1	1
Clec4n	ENSMUSG00000023349	0.0199974585097313	0.0599923755291938	0.455625354715449	0.683438032073173	1	1
Psmb8	ENSMUSG00000024338	0.000164597779190222	0.000493793337570666	0.397384062266614	0.596076093399921	0.853480389728993	0.853480389728993
Il1b	ENSMUSG00000027398	0.0751163767602349	0.112674565140352	0.347639524025037	0.347639524025037	0.00577209637898295	0.0173162891369488
Clec4e	ENSMUSG00000030142	0.184313766520423	0.294093936691129	0.447265995733381	0.447265995733381	0.196062624460753	0.294093936691129
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Fcer1g	ENSMUSG00000058715	0.000143939694472871	0.000431819083418612	0.345410946355104	0.511097249598474	0.511097249598474	0.511097249598474
Clec7a	ENSMUSG00000079293	0.0116356061791785	0.0349068185375355	0.578113371816017	0.578113371816017	0.348008842235184	0.522013263352777

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Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Apoe	ENSMUSG00000002985	0.01710279005982	0.0513083701794599	0.120545895661628	0.180818843492441	0.454942951775341	0.454942951775341
Csf1	ENSMUSG00000014599	0.024062085667391	0.0721862570021729	0.345037391052887	0.5155648232968	0.5155648232968	0.5155648232968
Apol7c	ENSMUSG00000044309	0.0171027900598199	0.0513083701794597	0.118714930081337	0.118714930081337	0.0969812105731562	0.118714930081337
Apol10b	ENSMUSG00000050014	0.0110666956860337	0.0332000870581011	1	1	0.853372965654504	1
Apol10a	ENSMUSG00000050982	0.000771096743445034	0.0023132902303351	0.178901132102685	0.268351698154027	0.782117202022501	0.782117202022501
Serpina10	ENSMUSG00000061947	0.0232795908282423	0.0349193862423635	0.0116356061791785	0.0349068185375355	0.0701431284016185	0.0701431284016185
Apol7e	ENSMUSG00000071716	0.0449262652924809	0.134778795877443	0.509144723230069	0.639337105615665	0.639337105615665	0.639337105615665
C4b	ENSMUSG00000073418	0.00163522353631957	0.0049056706089587	0.577829325134931	0.577829325134931	0.214764523938594	0.322146785907891
Apol11b	ENSMUSG00000091694	0.0969812105731563	0.290943631719469	0.57113445032749	0.852504981253341	0.852504981253341	0.852504981253341

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Interleukin-15 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Il2rb	ENSMUSG00000068227	0.0436072256433733	0.13082167693012	0.782117202022501	0.782117202022501	0.120545895661628	0.180818843492441

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Signaling by SCF-KIT

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Fyn	ENSMUSG00000019843	0.00376384688812124	0.0112915406643637	0.346527959006435	0.346527959006435	0.0171027900598199	0.0256541850897299
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477
Fes	ENSMUSG00000053158	0.146141353215796	0.255530331334266	0.255530331334266	0.255530331334266	0.179945789077372	0.255530331334266

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Proton/oligopeptide cotransporters

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Slc15a3	ENSMUSG00000024737	0.0226344734406829	0.0679034203220487	0.298599969973533	0.298599969973533	0.0953125666339397	0.14296884995091
Slc15a4	ENSMUSG00000029416	0.0964252305385472	0.17761387530773	0.177853449259986	0.177853449259986	0.118409250205154	0.17761387530773

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Growth hormone receptor signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat5a	ENSMUSG00000004043	0.0964252305385474	0.181732522866545	1	1	0.121155015244363	0.181732522866545
Stat5b	ENSMUSG00000020919	0.215852522998048	0.323778784497071	0.346156228791382	0.346156228791382	0.215127611919161	0.323778784497071
Lyn	ENSMUSG00000042228	0.0579478375430677	0.173843512629203	0.92589277149125	0.92589277149125	0.180293335960318	0.270440003940477

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grey

[1] “No significantly overrepresented pathways reported”

hotpink4

Axon guidance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ntn4	ENSMUSG00000020019	0.173632433887832	0.173632433887832	0.11993617140438	0.173632433887832	0.0575107614292585	0.172532284287776
Sema4a	ENSMUSG00000028064	0.180293335960318	0.540880007880955	0.452880492349546	0.642366752097095	0.642366752097095	0.642366752097095
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Farp2	ENSMUSG00000034066	0.455625354715449	0.683438032073173	0.925948247631505	0.925948247631505	0.215127611919161	0.645382835757484
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948
Arhgef11	ENSMUSG00000041977	0.455625354715448	1	1	1	0.92589277149125	1
Dock1	ENSMUSG00000058325	0.572616808177226	0.85892521226584	0.925444427431699	0.925444427431699	0.392243127063687	0.85892521226584
Erbb2	ENSMUSG00000062312	0.438889219142351	0.658333828713526	0.119631084167592	0.358893252502775	0.922189155665787	0.922189155665787

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Developmental Biology

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rxra	ENSMUSG00000015846	0.213307944885796	0.639923834657389	0.57466664340579	0.851061028660105	0.851061028660105	0.851061028660105
Ntn4	ENSMUSG00000020019	0.173632433887832	0.173632433887832	0.11993617140438	0.173632433887832	0.0575107614292585	0.172532284287776
Sema4a	ENSMUSG00000028064	0.180293335960318	0.540880007880955	0.452880492349546	0.642366752097095	0.642366752097095	0.642366752097095
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Smad3	ENSMUSG00000032402	1	1	0.853801250889739	1	0.514300775319626	1
Farp2	ENSMUSG00000034066	0.455625354715449	0.683438032073173	0.925948247631505	0.925948247631505	0.215127611919161	0.645382835757484
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948
Arhgef11	ENSMUSG00000041977	0.455625354715448	1	1	1	0.92589277149125	1
Foxo3	ENSMUSG00000048756	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041	0.782117202022501	0.926550375688041
Dsp	ENSMUSG00000054889	0.5155648232968	0.853694531487825	0.853694531487825	0.853694531487825	0.78148726569172	0.853694531487825
Dock1	ENSMUSG00000058325	0.572616808177226	0.85892521226584	0.925444427431699	0.925444427431699	0.392243127063687	0.85892521226584
Erbb2	ENSMUSG00000062312	0.438889219142351	0.658333828713526	0.119631084167592	0.358893252502775	0.922189155665787	0.922189155665787

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GAB1 signalosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pxn	ENSMUSG00000029528	0.347639524025037	0.924639851733043	0.84992097596507	0.924639851733043	0.924639851733043	0.924639851733043
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948

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MET activates PI3K/AKT signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948

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Nervous system development

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ntn4	ENSMUSG00000020019	0.173632433887832	0.173632433887832	0.11993617140438	0.173632433887832	0.0575107614292585	0.172532284287776
Sema4a	ENSMUSG00000028064	0.180293335960318	0.540880007880955	0.452880492349546	0.642366752097095	0.642366752097095	0.642366752097095
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Farp2	ENSMUSG00000034066	0.455625354715449	0.683438032073173	0.925948247631505	0.925948247631505	0.215127611919161	0.645382835757484
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948
Arhgef11	ENSMUSG00000041977	0.455625354715448	1	1	1	0.92589277149125	1
Dock1	ENSMUSG00000058325	0.572616808177226	0.85892521226584	0.925444427431699	0.925444427431699	0.392243127063687	0.85892521226584
Erbb2	ENSMUSG00000062312	0.438889219142351	0.658333828713526	0.119631084167592	0.358893252502775	0.922189155665787	0.922189155665787

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Nuclear Receptor transcription pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppard	ENSMUSG00000002250	0.255530331334265	0.766590994002796	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501
Nr2c1	ENSMUSG00000005897	0.450094379653806	0.675141569480709	0.179945789077371	0.539837367232114	0.925948247631505	0.925948247631505
Rxra	ENSMUSG00000015846	0.213307944885796	0.639923834657389	0.57466664340579	0.851061028660105	0.851061028660105	0.851061028660105
Vdr	ENSMUSG00000022479	1	1	0.926658283600152	1	0.926658283600152	1

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PI3K events in ERBB2 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gab1	ENSMUSG00000031714	0.711854160331342	0.711854160331342	0.573498913947369	0.711854160331342	0.254787123615605	0.711854160331342
Pik3r1	ENSMUSG00000041417	0.398829756175299	0.598244634262948	0.642366752097095	0.642366752097095	0.397384062266614	0.598244634262948
Erbb2	ENSMUSG00000062312	0.438889219142351	0.658333828713526	0.119631084167592	0.358893252502775	0.922189155665787	0.922189155665787

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Regulation of pyruvate dehydrogenase (PDH) complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppard	ENSMUSG00000002250	0.255530331334265	0.766590994002796	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501
Rxra	ENSMUSG00000015846	0.213307944885796	0.639923834657389	0.57466664340579	0.851061028660105	0.851061028660105	0.851061028660105
Pdhb	ENSMUSG00000021748	0.640101714462795	0.707687082601868	0.640101714462795	0.707687082601868	0.707687082601868	0.707687082601868

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Semaphorin interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sema4a	ENSMUSG00000028064	0.180293335960318	0.540880007880955	0.452880492349546	0.642366752097095	0.642366752097095	0.642366752097095
Farp2	ENSMUSG00000034066	0.455625354715449	0.683438032073173	0.925948247631505	0.925948247631505	0.215127611919161	0.645382835757484
Arhgef11	ENSMUSG00000041977	0.455625354715448	1	1	1	0.92589277149125	1
Erbb2	ENSMUSG00000062312	0.438889219142351	0.658333828713526	0.119631084167592	0.358893252502775	0.922189155665787	0.922189155665787

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Signaling by NODAL

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Smad3	ENSMUSG00000032402	1	1	0.853801250889739	1	0.514300775319626	1
Foxo3	ENSMUSG00000048756	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041	0.782117202022501	0.926550375688041

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Pyruvate metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppard	ENSMUSG00000002250	0.255530331334265	0.766590994002796	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501
Rxra	ENSMUSG00000015846	0.213307944885796	0.639923834657389	0.57466664340579	0.851061028660105	0.851061028660105	0.851061028660105
Pdhb	ENSMUSG00000021748	0.640101714462795	0.707687082601868	0.640101714462795	0.707687082601868	0.707687082601868	0.707687082601868

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The citric acid (TCA) cycle and respiratory electron transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ppard	ENSMUSG00000002250	0.255530331334265	0.766590994002796	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501
Rxra	ENSMUSG00000015846	0.213307944885796	0.639923834657389	0.57466664340579	0.851061028660105	0.851061028660105	0.851061028660105
Pdhb	ENSMUSG00000021748	0.640101714462795	0.707687082601868	0.640101714462795	0.707687082601868	0.707687082601868	0.707687082601868
Ndufa6	ENSMUSG00000022450	0.0964252305385472	0.289275691615642	0.85117361048289	0.85117361048289	0.778911768167544	0.85117361048289
Pm20d1	ENSMUSG00000042251	0.57466664340579	0.853480389728993	0.852175490580835	0.853480389728993	0.853480389728993	0.853480389728993
Cycs	ENSMUSG00000063694	0.390750658104794	0.851732715229127	0.706616781330066	0.851732715229127	0.851732715229127	0.851732715229127

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FOXO-mediated transcription of cell cycle genes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Smad3	ENSMUSG00000032402	1	1	0.853801250889739	1	0.514300775319626	1
Foxo3	ENSMUSG00000048756	0.853694531487825	0.926550375688041	0.926550375688041	0.926550375688041	0.782117202022501	0.926550375688041

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indianred

NOD-like receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441
Rnf31	ENSMUSG00000047098	0.926658283600152	0.926658283600152	0.0331400397096515	0.0994201191289544	0.399548817627028	0.599323226440542

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Measles

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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Hepatitis C

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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Influenza A

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Tnfsf10	ENSMUSG00000039304	0.180293335960318	0.323235417174495	0.21549027811633	0.323235417174495	0.853694531487825	0.853694531487825
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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Epstein-Barr virus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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Coronavirus disease - COVID-19

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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Necroptosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
Tnfsf10	ENSMUSG00000039304	0.180293335960318	0.323235417174495	0.21549027811633	0.323235417174495	0.853694531487825	0.853694531487825
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441
Rnf31	ENSMUSG00000047098	0.926658283600152	0.926658283600152	0.0331400397096515	0.0994201191289544	0.399548817627028	0.599323226440542

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PD-L1 expression and PD-1 checkpoint pathway in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hif1a	ENSMUSG00000021109	0.780851835278818	0.780851835278818	0.514934023620345	0.772401035430517	0.146141353215796	0.438424059647387
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Tirap	ENSMUSG00000032041	0.710208797518812	0.710208797518812	0.0761127945805736	0.228338383741721	0.174692232033629	0.262038348050444

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Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Irf9	ENSMUSG00000002325	0.18064054691103	0.254414773803597	0.0334587898203824	0.100376369461147	0.254414773803597	0.254414773803597
2810021J22Rik	ENSMUSG00000020491	0.344663224299303	0.344663224299303	0.216214347033995	0.324321520550992	0.120850531362929	0.324321520550992
Traf6	ENSMUSG00000027164	0.778911768167544	0.778911768167544	0.0113089139751576	0.0339267419254727	0.214037080764326	0.321055621146488
Oas3	ENSMUSG00000032661	0.514934023620345	0.514934023620345	0.120850531362929	0.362551594088788	0.397384062266614	0.514934023620345
Oas2	ENSMUSG00000032690	0.346899083932133	0.346899083932133	0.010906560635693	0.032719681907079	0.0741204440774084	0.111180666116113
Stat2	ENSMUSG00000040033	0.643853282854191	0.643853282854191	0.0443599545252853	0.133079863575856	0.120545895661628	0.180818843492441

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lightblue

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Mitotic Metaphase and Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Mitotic Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Amplification of signal from the kinetochores

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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EML4 and NUDC in mitotic spindle formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Mitotic Spindle Checkpoint

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Resolution of Sister Chromatid Cohesion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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RHO GTPases Activate Formins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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M Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Separation of Sister Chromatids

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Mitotic Prometaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Kinesins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Cell Cycle, Mitotic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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RHO GTPase Effectors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Classical Kir channels

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kcnj14	ENSMUSG00000058743	0.51398322803049	0.711240436189781	0.453570536021945	0.711240436189781	0.711240436189781	0.711240436189781

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Cell Cycle Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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COPI-dependent Golgi-to-ER retrograde traffic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Signaling by Rho GTPases, Miro GTPases and RHOBTB3

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Regulation of FOXO transcriptional activity by acetylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kat2b	ENSMUSG00000000708	0.514934023620345	0.772401035430517	0.255901190956604	0.767703572869811	0.781170242226513	0.781170242226513

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Regulation of cholesterol biosynthesis by SREBP (SREBF)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kpnb1	ENSMUSG00000001440	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721	0.511742979522636	0.511742979522636

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Factors involved in megakaryocyte development and platelet production

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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Signaling by Rho GTPases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Mapre1	ENSMUSG00000027479	0.496922356453102	0.745383534679652	0.058823267388015	0.176469802164045	0.769866760519794	0.769866760519794
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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YAP1- and WWTR1 (TAZ)-stimulated gene expression

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kat2b	ENSMUSG00000000708	0.514934023620345	0.772401035430517	0.255901190956604	0.767703572869811	0.781170242226513	0.781170242226513

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Golgi-to-ER retrograde transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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MHC class II antigen presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif2a	ENSMUSG00000021693	0.21549027811633	0.323235417174495	0.0763619660358787	0.229085898107636	1	1
Kif2c	ENSMUSG00000028678	1	1	0.923011676492635	1	0.399189600887034	1

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NOTCH1 Intracellular Domain Regulates Transcription

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kat2b	ENSMUSG00000000708	0.514934023620345	0.772401035430517	0.255901190956604	0.767703572869811	0.781170242226513	0.781170242226513

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HDL remodeling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lipg	ENSMUSG00000053846	0.252545530864481	0.378818296296722	0.0958690133561599	0.28760704006848	0.9255572759333	0.9255572759333

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RUNX3 regulates NOTCH signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kat2b	ENSMUSG00000000708	0.514934023620345	0.772401035430517	0.255901190956604	0.767703572869811	0.781170242226513	0.781170242226513

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lightblue2

Endometrial cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Ctnna1	ENSMUSG00000037815	0.5155648232968	0.853801250889739	0.710001140920767	0.853801250889739	0.853801250889739	0.853801250889739
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Hepatocellular carcinoma

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Gstm5	ENSMUSG00000004032	0.711240436189781	0.853801250889739	0.511742979522636	0.853801250889739	0.853801250889739	0.853801250889739
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321

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Colorectal cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Glioma

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Gastric cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Ctnna1	ENSMUSG00000037815	0.5155648232968	0.853801250889739	0.710001140920767	0.853801250889739	0.853801250889739	0.853801250889739
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Chronic myeloid leukemia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Thyroid cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Tpm3	ENSMUSG00000027940	0.343537039781257	0.515305559671886	0.0693988029824257	0.208196408947277	0.57466664340579	0.57466664340579
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Cellular senescence

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Mcu	ENSMUSG00000009647	0.85117361048289	0.85117361048289	0.643359829732651	0.85117361048289	0.573498913947369	0.85117361048289
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Capn1	ENSMUSG00000024942	0.575536202757516	0.708745765211584	0.708745765211584	0.708745765211584	0.453225835454266	0.708745765211584
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Hipk4	ENSMUSG00000040424	0.0969812105731562	0.290943631719469	0.299349060054895	0.449023590082343	0.926003599371282	0.926003599371282
Zfp36l2	ENSMUSG00000045817	0.400265374208515	0.513026869856283	0.513026869856283	0.513026869856283	0.058823267388015	0.176469802164045
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Spliceosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sf3a1	ENSMUSG00000002129	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Sf3a2	ENSMUSG00000020211	0.180293335960318	0.540880007880954	0.852065168704833	0.852065168704833	0.575824878403157	0.852065168704833
Snw1	ENSMUSG00000021039	0.395196379647461	0.514934023620345	0.514934023620345	0.514934023620345	0.398829756175299	0.514934023620345
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Cdc5l	ENSMUSG00000023932	0.344663224299303	0.638824656785692	0.509798138101151	0.638824656785692	0.638824656785692	0.638824656785692
Rbm22	ENSMUSG00000024604	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	1	1
Sf3b2	ENSMUSG00000024853	0.400265374208515	0.853480389728993	0.643359829732651	0.853480389728993	0.853480389728993	0.853480389728993
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Wbp11	ENSMUSG00000030216	0.297848640636702	0.893545921910107	0.926333123228344	0.926333123228344	0.7802108304765	0.926333123228344
Pqbp1	ENSMUSG00000031157	0.134789313526392	0.202183970289588	0.093084640707941	0.202183970289588	0.926441990075769	0.926441990075769

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Hippo signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Lats2	ENSMUSG00000021959	0.57466664340579	0.57466664340579	0.447265995733381	0.57466664340579	0.344663224299303	0.57466664340579
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Trp53bp2	ENSMUSG00000026510	0.453225835454266	0.704220158648919	0.573498913947369	0.704220158648919	0.704220158648919	0.704220158648919
Ctnna1	ENSMUSG00000037815	0.5155648232968	0.853801250889739	0.710001140920767	0.853801250889739	0.853801250889739	0.853801250889739
Ppp2r2d	ENSMUSG00000041769	0.513665062682276	0.770497594023414	0.853694531487825	0.853694531487825	0.254787123615605	0.764361370846816

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Adherens junction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Ptpn1	ENSMUSG00000027540	0.711854160331342	0.853694531487825	0.710001140920767	0.853694531487825	0.853694531487825	0.853694531487825
Wasf2	ENSMUSG00000028868	0.779238691542963	0.779238691542963	0.214764523938594	0.644293571815781	0.575536202757516	0.779238691542963
Ssx2ip	ENSMUSG00000036825	0.781645261743309	0.781645261743309	0.344288444541856	0.516432666812784	0.297472133192261	0.516432666812784
Ctnna1	ENSMUSG00000037815	0.5155648232968	0.853801250889739	0.710001140920767	0.853801250889739	0.853801250889739	0.853801250889739
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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ErbB signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Endocytosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rab5b	ENSMUSG00000000711	0.642864324224729	0.925669613555092	0.852504981253341	0.925669613555092	0.925669613555092	0.925669613555092
Git1	ENSMUSG00000011877	0.851061028660105	0.851061028660105	0.77858338846904	0.851061028660105	0.7802108304765	0.851061028660105
Snx3	ENSMUSG00000019804	0.451840588205062	0.677760882307593	0.118409250205154	0.355227750615461	0.78180291566155	0.78180291566155
Rufy1	ENSMUSG00000020375	0.572616808177226	0.572616808177226	0.509798138101151	0.572616808177226	0.508488713161374	0.572616808177226
Asap1	ENSMUSG00000022377	0.297848640636702	0.711034989117171	0.575536202757516	0.711034989117171	0.711034989117171	0.711034989117171
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Nedd4l	ENSMUSG00000024589	0.847921313356738	0.847921313356738	0.236337185850514	0.378818296296721	0.252545530864481	0.378818296296721
Hgs	ENSMUSG00000025793	0.297095062262363	0.891285186787088	0.85117361048289	1	1	1
Clta	ENSMUSG00000028478	0.853480389728993	0.853480389728993	0.255901190956604	0.383851786434906	0.249907451332337	0.383851786434906
Capzb	ENSMUSG00000028745	0.399548817627028	0.578113371816017	0.513026869856283	0.578113371816017	0.578113371816017	0.578113371816017
Sh3gl3	ENSMUSG00000030638	0.643359829732651	1	1	1	0.853372965654504	1
Pdcd6ip	ENSMUSG00000032504	0.92622377157404	0.92622377157404	0.711854160331342	0.92622377157404	0.640355507848752	0.92622377157404
Smap2	ENSMUSG00000032870	0.211844580334808	0.635533741004424	0.853372965654504	0.853372965654504	0.711034989117171	0.853372965654504
Wipf2	ENSMUSG00000038013	0.454600801949285	0.509798138101151	0.499022251664193	0.509798138101151	0.509798138101151	0.509798138101151
Chmp4b	ENSMUSG00000038467	0.299349060054895	0.522013263352777	0.643853282854191	0.643853282854191	0.348008842235184	0.522013263352777
Arf6	ENSMUSG00000044147	0.711854160331342	0.926550375688041	0.926550375688041	0.926550375688041	0.118714930081337	0.35614479024401

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Viral carcinogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Srf	ENSMUSG00000015605	0.395928178642446	0.777255087907932	0.573498913947369	0.777255087907932	0.777255087907932	0.777255087907932
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Snw1	ENSMUSG00000021039	0.395196379647461	0.514934023620345	0.514934023620345	0.514934023620345	0.398829756175299	0.514934023620345
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Ubr4	ENSMUSG00000066036	0.578113371816017	0.962800648467296	0.641867098978198	0.962800648467296	1	1
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421

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Non-small cell lung cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Gastric acid secretion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Atp4a	ENSMUSG00000005553	0.778911768167544	0.852065168704833	0.852065168704833	0.852065168704833	0.706616781330066	0.852065168704833
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Atp1b1	ENSMUSG00000026576	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041	0.513665062682276	0.926550375688041
Gnai2	ENSMUSG00000032562	0.577829325134931	0.926333123228344	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344
Kcnj10	ENSMUSG00000044708	0.178901132102684	0.268351698154027	0.17433930265919	0.268351698154027	0.775044679571913	0.775044679571913
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1

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Hepatitis B

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Tab2	ENSMUSG00000015755	1	1	0.147458757705095	0.442376273115284	0.776919261684345	1
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Pathways in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axin2	ENSMUSG00000000142	0.175044824745981	0.179945789077372	0.0441715176243983	0.132514552873195	0.179945789077372	0.179945789077372
Cdh1	ENSMUSG00000000303	0.707899741868332	0.708534948098332	0.45596561163947	0.708534948098332	0.708534948098332	0.708534948098332
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Gstm5	ENSMUSG00000004032	0.711240436189781	0.853801250889739	0.511742979522636	0.853801250889739	0.853801250889739	0.853801250889739
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Epas1	ENSMUSG00000024140	1	1	0.853372965654504	1	0.710208797518812	1
Axin1	ENSMUSG00000024182	1	1	0.253294730253594	0.379942095380391	0.21549027811633	0.379942095380391
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Tpm3	ENSMUSG00000027940	0.343537039781257	0.515305559671886	0.0693988029824257	0.208196408947277	0.57466664340579	0.57466664340579
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Il15	ENSMUSG00000031712	0.254414773803597	0.381622160705395	0.576973746230334	0.576973746230334	0.211844580334808	0.381622160705395
Gnai2	ENSMUSG00000032562	0.577829325134931	0.926333123228344	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344
Ctnna1	ENSMUSG00000037815	0.5155648232968	0.853801250889739	0.710001140920767	0.853801250889739	0.853801250889739	0.853801250889739
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Max	ENSMUSG00000059436	0.577829325134931	0.853694531487825	0.853694531487825	0.853694531487825	0.300095920620218	0.853694531487825
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Pancreatic cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Human cytomegalovirus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Calr	ENSMUSG00000003814	0.78148726569172	0.852940894477647	0.577829325134931	0.852940894477647	0.852940894477647	0.852940894477647
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Elk1	ENSMUSG00000009406	0.505169133438821	0.513665062682276	0.511742979522636	0.513665062682276	0.513665062682276	0.513665062682276
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Sos1	ENSMUSG00000024241	0.253294730253594	0.642366752097095	0.572616808177226	0.642366752097095	0.642366752097095	0.642366752097095
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Pdia3	ENSMUSG00000027248	0.570836132666921	0.848872227545608	0.848872227545608	0.848872227545608	0.148115998140416	0.444347994421247
Bcar1	ENSMUSG00000031955	0.779238691542963	0.9255572759333	0.9255572759333	0.9255572759333	0.449391287230099	0.9255572759333
Gnai2	ENSMUSG00000032562	0.577829325134931	0.926333123228344	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Protein processing in endoplasmic reticulum

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calr	ENSMUSG00000003814	0.78148726569172	0.852940894477647	0.577829325134931	0.852940894477647	0.852940894477647	0.852940894477647
Dnajb11	ENSMUSG00000004460	0.926658283600152	0.926658283600152	0.710416009055326	0.926658283600152	0.514300775319626	0.926658283600152
Ufd1l	ENSMUSG00000005262	0.853372965654504	0.853372965654504	0.34837756124189	0.522566341862834	0.00637724014320526	0.0191317204296158
Erlec1	ENSMUSG00000020311	0.568123100704554	0.780049698709835	0.780049698709835	0.780049698709835	0.296717426617604	0.780049698709835
Capn1	ENSMUSG00000024942	0.575536202757516	0.708745765211584	0.708745765211584	0.708745765211584	0.453225835454266	0.708745765211584
Sec61a2	ENSMUSG00000025816	1	1	0.924872384323463	1	1	1
Pdia3	ENSMUSG00000027248	0.570836132666921	0.848872227545608	0.848872227545608	0.848872227545608	0.148115998140416	0.444347994421247
Hyou1	ENSMUSG00000032115	0.78148726569172	0.78148726569172	0.578113371816017	0.78148726569172	0.399548817627028	0.78148726569172
Stt3b	ENSMUSG00000032437	0.299349060054895	0.853907737111068	0.853907737111068	0.853907737111068	0.643853282854191	0.853907737111068
Ckap4	ENSMUSG00000046841	0.0766111619812296	0.229833485943689	0.710416009055326	0.710416009055326	0.638824656785692	0.710416009055326
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152

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Epstein-Barr virus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ddb2	ENSMUSG00000002109	0.926003599371281	0.926003599371281	0.7802108304765	0.926003599371281	0.5155648232968	0.926003599371281
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Calr	ENSMUSG00000003814	0.78148726569172	0.852940894477647	0.577829325134931	0.852940894477647	0.852940894477647	0.852940894477647
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Tab2	ENSMUSG00000015755	1	1	0.147458757705095	0.442376273115284	0.776919261684345	1
Snw1	ENSMUSG00000021039	0.395196379647461	0.514934023620345	0.514934023620345	0.514934023620345	0.398829756175299	0.514934023620345
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Pdia3	ENSMUSG00000027248	0.570836132666921	0.848872227545608	0.848872227545608	0.848872227545608	0.148115998140416	0.444347994421247
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Entpd8	ENSMUSG00000036813	0.708534948098331	0.708534948098331	0.177153312234059	0.531459936702178	0.643359829732651	0.708534948098331
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152

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Cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Rad21	ENSMUSG00000022314	0.505838378028518	0.9255572759333	0.778911768167544	0.9255572759333	0.9255572759333	0.9255572759333
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993

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AGE-RAGE signaling pathway in diabetic complications

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Diap1	ENSMUSG00000024456	0.781170242226513	0.781170242226513	0.781170242226513	0.781170242226513	0.400265374208515	0.781170242226513
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Prkce	ENSMUSG00000045038	0.514934023620345	0.78148726569172	0.78148726569172	0.78148726569172	0.638824656785692	0.78148726569172
Prkca	ENSMUSG00000050965	1	1	0.636229315311352	1	1	1
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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mRNA surveillance pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pabpc1	ENSMUSG00000022283	0.926003599371282	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Etf1	ENSMUSG00000024360	0.700855417205622	0.773122046545957	0.773122046545957	0.773122046545957	0.346899083932133	0.773122046545957
Srrm1	ENSMUSG00000028809	0.45596561163947	0.683948417459205	0.0766111619812296	0.229833485943689	0.853372965654504	0.853372965654504
Smg6	ENSMUSG00000038290	0.299349060054895	0.898047180164686	0.853907737111068	0.926441990075769	0.926441990075769	0.926441990075769
Ppp2r2d	ENSMUSG00000041769	0.513665062682276	0.770497594023414	0.853694531487825	0.853694531487825	0.254787123615605	0.764361370846816
Smg7	ENSMUSG00000042772	0.78180291566155	0.78180291566155	0.299349060054895	0.770497594023414	0.513665062682276	0.770497594023414
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125

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RNA degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
C1d	ENSMUSG00000000581	0.577829325134931	0.866743987702397	0.926658283600152	0.926658283600152	0.454942951775342	0.866743987702397
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Pabpc1	ENSMUSG00000022283	0.926003599371282	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404
Hspd1	ENSMUSG00000025980	0.446194239410717	0.562855697645602	0.562855697645602	0.562855697645602	0.249528554620971	0.562855697645602
Dcp1b	ENSMUSG00000041477	0.148772260628989	0.223158390943484	0.0936419271039908	0.223158390943484	0.853372965654504	0.853372965654504
Patl1	ENSMUSG00000046139	0.643853282854191	0.708323672944427	0.708323672944427	0.708323672944427	0.342026805366747	0.708323672944427
Tob2	ENSMUSG00000048546	0.781170242226513	0.781170242226513	0.514934023620345	0.772401035430517	0.299349060054895	0.772401035430517

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Gene expression (Transcription)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Supt6	ENSMUSG00000002052	0.300095920620218	0.900287761860654	0.926333123228344	0.926333123228344	0.78148726569172	0.926333123228344
Med6	ENSMUSG00000002679	0.851061028660105	0.925837170483845	0.925837170483845	0.925837170483845	0.709166031912266	0.925837170483845
Med25	ENSMUSG00000002968	0.254041925545275	0.679838753181399	0.705098431925329	0.705098431925329	0.453225835454266	0.679838753181399
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Stk11	ENSMUSG00000003068	0.781170242226513	1	0.347639524025037	1	1	1
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Ctr9	ENSMUSG00000005609	0.29252580908486	0.853480389728993	0.640355507848752	0.853480389728993	0.853480389728993	0.853480389728993
Med15	ENSMUSG00000012114	0.780851835278817	0.780851835278817	0.398108175780842	0.780851835278817	0.640861491578951	0.780851835278817
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Surf1	ENSMUSG00000015790	0.926333123228344	0.926333123228344	0.514934023620344	0.926333123228344	0.640861491578951	0.926333123228344
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ppm1d	ENSMUSG00000020525	0.514934023620344	0.577829325134931	0.300095920620217	0.577829325134931	0.577829325134931	0.577829325134931
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Mta1	ENSMUSG00000021144	0.641867098978198	1	1	1	0.926550375688041	1
Ppp1r13b	ENSMUSG00000021285	0.706831781264721	0.7802108304765	0.778253541606068	0.7802108304765	0.7802108304765	0.7802108304765
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Brd2	ENSMUSG00000024335	0.711854160331342	1	1	1	0.78180291566155	1
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Nedd4l	ENSMUSG00000024589	0.847921313356738	0.847921313356738	0.236337185850514	0.378818296296721	0.252545530864481	0.378818296296721
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Nabp2	ENSMUSG00000025374	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041	0.782117202022501	0.926550375688041
Gls	ENSMUSG00000026103	0.853372965654504	0.853372965654504	0.643359829732651	0.853372965654504	0.5155648232968	0.853372965654504
Rtf1	ENSMUSG00000027304	0.293293089483362	0.848280005680805	0.769496350735448	0.848280005680805	0.848280005680805	0.848280005680805
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Polr3c	ENSMUSG00000028099	0.148772260628989	0.446316781886968	0.9255572759333	0.9255572759333	0.575536202757516	0.863304304136274
Rprd2	ENSMUSG00000028106	0.926550375688041	0.926550375688041	0.454600801949285	0.926550375688041	0.853372965654504	0.926550375688041
Tceb3	ENSMUSG00000028668	0.300095920620218	0.450143880930327	0.290984282074805	0.450143880930327	0.852065168704833	0.852065168704833
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Nelfa	ENSMUSG00000029111	0.642366752097095	0.926333123228344	0.926333123228344	0.926333123228344	0.643359829732651	0.926333123228344
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Cox7b	ENSMUSG00000031231	0.514300775319626	0.771451162979439	0.246478961478169	0.739436884434508	0.7802108304765	0.7802108304765
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
9630033F20Rik	ENSMUSG00000038028	0.926333123228344	0.926333123228344	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773
Ppp1r13l	ENSMUSG00000040734	0.290984282074805	0.299349060054896	0.299349060054896	0.299349060054896	0.120545895661628	0.299349060054896
Setd1a	ENSMUSG00000042308	0.711854160331342	0.711854160331342	0.211844580334808	0.635533741004424	0.711240436189781	0.711854160331342
Ago4	ENSMUSG00000042500	0.511742979522636	0.643853282854191	0.513665062682276	0.643853282854191	0.643853282854191	0.643853282854191
Zfp354c	ENSMUSG00000044807	0.449391287230099	0.851843781957086	0.577544706586058	0.851843781957086	0.851843781957086	0.851843781957086
E2f8	ENSMUSG00000046179	0.578113371816017	0.578113371816017	0.450444934184774	0.578113371816017	0.514300775319626	0.578113371816017
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Zfp710	ENSMUSG00000048897	0.7802108304765	0.851732715229127	0.575824878403157	0.851732715229127	0.851732715229127	0.851732715229127
Foxo6	ENSMUSG00000052135	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.643853282854191	0.781170242226513
Pom121	ENSMUSG00000053293	0.255530331334266	0.383295497001398	0.209636747299872	0.383295497001398	0.705968934865368	0.705968934865368
Zfp457	ENSMUSG00000055341	1	1	0.21549027811633	0.64647083434899	0.455284468727762	0.682926703091643
Mta3	ENSMUSG00000055817	0.853480389728993	0.853480389728993	0.780851835278818	0.853480389728993	0.578396848531894	0.853480389728993
Max	ENSMUSG00000059436	0.577829325134931	0.853694531487825	0.853694531487825	0.853694531487825	0.300095920620218	0.853694531487825
Tmem219	ENSMUSG00000060538	0.0236697127745139	0.0355045691617709	0.0201177688382032	0.0355045691617709	0.629211154902385	0.629211154902385
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421
Sco1	ENSMUSG00000069844	0.400265374208515	0.400265374208515	0.214037080764325	0.321055621146488	0.148115998140416	0.321055621146488
Nrbf2	ENSMUSG00000075000	0.576973746230334	0.78148726569172	0.211844580334808	0.635533741004424	0.78148726569172	0.78148726569172
AU041133	ENSMUSG00000078435	0.853480389728993	0.853480389728993	0.148115998140416	0.442231101684348	0.294820734456232	0.442231101684348
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125
Zfp703	ENSMUSG00000085795	0.642864324224729	0.926333123228344	0.926333123228344	0.926333123228344	0.45596561163947	0.926333123228344
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517
Med20	ENSMUSG00000092558	0.451840588205062	0.575824878403157	0.454942951775341	0.575824878403157	0.575824878403157	0.575824878403157
Zfp433	ENSMUSG00000096795	0.782117202022501	0.853480389728993	0.254414773803597	0.763244321410791	0.853480389728993	0.853480389728993

Download data as csv

RNA Polymerase II Transcription

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Supt6	ENSMUSG00000002052	0.300095920620218	0.900287761860654	0.926333123228344	0.926333123228344	0.78148726569172	0.926333123228344
Med6	ENSMUSG00000002679	0.851061028660105	0.925837170483845	0.925837170483845	0.925837170483845	0.709166031912266	0.925837170483845
Med25	ENSMUSG00000002968	0.254041925545275	0.679838753181399	0.705098431925329	0.705098431925329	0.453225835454266	0.679838753181399
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Stk11	ENSMUSG00000003068	0.781170242226513	1	0.347639524025037	1	1	1
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Ctr9	ENSMUSG00000005609	0.29252580908486	0.853480389728993	0.640355507848752	0.853480389728993	0.853480389728993	0.853480389728993
Med15	ENSMUSG00000012114	0.780851835278817	0.780851835278817	0.398108175780842	0.780851835278817	0.640861491578951	0.780851835278817
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Surf1	ENSMUSG00000015790	0.926333123228344	0.926333123228344	0.514934023620344	0.926333123228344	0.640861491578951	0.926333123228344
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ppm1d	ENSMUSG00000020525	0.514934023620344	0.577829325134931	0.300095920620217	0.577829325134931	0.577829325134931	0.577829325134931
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ppp1r13b	ENSMUSG00000021285	0.706831781264721	0.7802108304765	0.778253541606068	0.7802108304765	0.7802108304765	0.7802108304765
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Brd2	ENSMUSG00000024335	0.711854160331342	1	1	1	0.78180291566155	1
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Nedd4l	ENSMUSG00000024589	0.847921313356738	0.847921313356738	0.236337185850514	0.378818296296721	0.252545530864481	0.378818296296721
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Nabp2	ENSMUSG00000025374	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041	0.782117202022501	0.926550375688041
Gls	ENSMUSG00000026103	0.853372965654504	0.853372965654504	0.643359829732651	0.853372965654504	0.5155648232968	0.853372965654504
Rtf1	ENSMUSG00000027304	0.293293089483362	0.848280005680805	0.769496350735448	0.848280005680805	0.848280005680805	0.848280005680805
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Rprd2	ENSMUSG00000028106	0.926550375688041	0.926550375688041	0.454600801949285	0.926550375688041	0.853372965654504	0.926550375688041
Tceb3	ENSMUSG00000028668	0.300095920620218	0.450143880930327	0.290984282074805	0.450143880930327	0.852065168704833	0.852065168704833
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Nelfa	ENSMUSG00000029111	0.642366752097095	0.926333123228344	0.926333123228344	0.926333123228344	0.643359829732651	0.926333123228344
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Cox7b	ENSMUSG00000031231	0.514300775319626	0.771451162979439	0.246478961478169	0.739436884434508	0.7802108304765	0.7802108304765
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
9630033F20Rik	ENSMUSG00000038028	0.926333123228344	0.926333123228344	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773
Ppp1r13l	ENSMUSG00000040734	0.290984282074805	0.299349060054896	0.299349060054896	0.299349060054896	0.120545895661628	0.299349060054896
Setd1a	ENSMUSG00000042308	0.711854160331342	0.711854160331342	0.211844580334808	0.635533741004424	0.711240436189781	0.711854160331342
Zfp354c	ENSMUSG00000044807	0.449391287230099	0.851843781957086	0.577544706586058	0.851843781957086	0.851843781957086	0.851843781957086
E2f8	ENSMUSG00000046179	0.578113371816017	0.578113371816017	0.450444934184774	0.578113371816017	0.514300775319626	0.578113371816017
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Zfp710	ENSMUSG00000048897	0.7802108304765	0.851732715229127	0.575824878403157	0.851732715229127	0.851732715229127	0.851732715229127
Foxo6	ENSMUSG00000052135	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.643853282854191	0.781170242226513
Zfp457	ENSMUSG00000055341	1	1	0.21549027811633	0.64647083434899	0.455284468727762	0.682926703091643
Max	ENSMUSG00000059436	0.577829325134931	0.853694531487825	0.853694531487825	0.853694531487825	0.300095920620218	0.853694531487825
Tmem219	ENSMUSG00000060538	0.0236697127745139	0.0355045691617709	0.0201177688382032	0.0355045691617709	0.629211154902385	0.629211154902385
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421
Sco1	ENSMUSG00000069844	0.400265374208515	0.400265374208515	0.214037080764325	0.321055621146488	0.148115998140416	0.321055621146488
Nrbf2	ENSMUSG00000075000	0.576973746230334	0.78148726569172	0.211844580334808	0.635533741004424	0.78148726569172	0.78148726569172
AU041133	ENSMUSG00000078435	0.853480389728993	0.853480389728993	0.148115998140416	0.442231101684348	0.294820734456232	0.442231101684348
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125
Zfp703	ENSMUSG00000085795	0.642864324224729	0.926333123228344	0.926333123228344	0.926333123228344	0.45596561163947	0.926333123228344
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517
Med20	ENSMUSG00000092558	0.451840588205062	0.575824878403157	0.454942951775341	0.575824878403157	0.575824878403157	0.575824878403157
Zfp433	ENSMUSG00000096795	0.782117202022501	0.853480389728993	0.254414773803597	0.763244321410791	0.853480389728993	0.853480389728993

Download data as csv

Transcriptional Regulation by TP53

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Stk11	ENSMUSG00000003068	0.781170242226513	1	0.347639524025037	1	1	1
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Surf1	ENSMUSG00000015790	0.926333123228344	0.926333123228344	0.514934023620344	0.926333123228344	0.640861491578951	0.926333123228344
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ppp1r13b	ENSMUSG00000021285	0.706831781264721	0.7802108304765	0.778253541606068	0.7802108304765	0.7802108304765	0.7802108304765
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Gls	ENSMUSG00000026103	0.853372965654504	0.853372965654504	0.643359829732651	0.853372965654504	0.5155648232968	0.853372965654504
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Tceb3	ENSMUSG00000028668	0.300095920620218	0.450143880930327	0.290984282074805	0.450143880930327	0.852065168704833	0.852065168704833
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Nelfa	ENSMUSG00000029111	0.642366752097095	0.926333123228344	0.926333123228344	0.926333123228344	0.643359829732651	0.926333123228344
Cox7b	ENSMUSG00000031231	0.514300775319626	0.771451162979439	0.246478961478169	0.739436884434508	0.7802108304765	0.7802108304765
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012
9630033F20Rik	ENSMUSG00000038028	0.926333123228344	0.926333123228344	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773
Ppp1r13l	ENSMUSG00000040734	0.290984282074805	0.299349060054896	0.299349060054896	0.299349060054896	0.120545895661628	0.299349060054896
E2f8	ENSMUSG00000046179	0.578113371816017	0.578113371816017	0.450444934184774	0.578113371816017	0.514300775319626	0.578113371816017
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Tmem219	ENSMUSG00000060538	0.0236697127745139	0.0355045691617709	0.0201177688382032	0.0355045691617709	0.629211154902385	0.629211154902385
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Sco1	ENSMUSG00000069844	0.400265374208515	0.400265374208515	0.214037080764325	0.321055621146488	0.148115998140416	0.321055621146488
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517

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Generic Transcription Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Med6	ENSMUSG00000002679	0.851061028660105	0.925837170483845	0.925837170483845	0.925837170483845	0.709166031912266	0.925837170483845
Med25	ENSMUSG00000002968	0.254041925545275	0.679838753181399	0.705098431925329	0.705098431925329	0.453225835454266	0.679838753181399
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Stk11	ENSMUSG00000003068	0.781170242226513	1	0.347639524025037	1	1	1
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Med15	ENSMUSG00000012114	0.780851835278817	0.780851835278817	0.398108175780842	0.780851835278817	0.640861491578951	0.780851835278817
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Surf1	ENSMUSG00000015790	0.926333123228344	0.926333123228344	0.514934023620344	0.926333123228344	0.640861491578951	0.926333123228344
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ppm1d	ENSMUSG00000020525	0.514934023620344	0.577829325134931	0.300095920620217	0.577829325134931	0.577829325134931	0.577829325134931
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ppp1r13b	ENSMUSG00000021285	0.706831781264721	0.7802108304765	0.778253541606068	0.7802108304765	0.7802108304765	0.7802108304765
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Brd2	ENSMUSG00000024335	0.711854160331342	1	1	1	0.78180291566155	1
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Nedd4l	ENSMUSG00000024589	0.847921313356738	0.847921313356738	0.236337185850514	0.378818296296721	0.252545530864481	0.378818296296721
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Gls	ENSMUSG00000026103	0.853372965654504	0.853372965654504	0.643359829732651	0.853372965654504	0.5155648232968	0.853372965654504
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Tceb3	ENSMUSG00000028668	0.300095920620218	0.450143880930327	0.290984282074805	0.450143880930327	0.852065168704833	0.852065168704833
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Nelfa	ENSMUSG00000029111	0.642366752097095	0.926333123228344	0.926333123228344	0.926333123228344	0.643359829732651	0.926333123228344
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Cox7b	ENSMUSG00000031231	0.514300775319626	0.771451162979439	0.246478961478169	0.739436884434508	0.7802108304765	0.7802108304765
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012
9630033F20Rik	ENSMUSG00000038028	0.926333123228344	0.926333123228344	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773
Ppp1r13l	ENSMUSG00000040734	0.290984282074805	0.299349060054896	0.299349060054896	0.299349060054896	0.120545895661628	0.299349060054896
Setd1a	ENSMUSG00000042308	0.711854160331342	0.711854160331342	0.211844580334808	0.635533741004424	0.711240436189781	0.711854160331342
Zfp354c	ENSMUSG00000044807	0.449391287230099	0.851843781957086	0.577544706586058	0.851843781957086	0.851843781957086	0.851843781957086
E2f8	ENSMUSG00000046179	0.578113371816017	0.578113371816017	0.450444934184774	0.578113371816017	0.514300775319626	0.578113371816017
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Zfp710	ENSMUSG00000048897	0.7802108304765	0.851732715229127	0.575824878403157	0.851732715229127	0.851732715229127	0.851732715229127
Foxo6	ENSMUSG00000052135	0.578113371816017	0.781170242226513	0.781170242226513	0.781170242226513	0.643853282854191	0.781170242226513
Zfp457	ENSMUSG00000055341	1	1	0.21549027811633	0.64647083434899	0.455284468727762	0.682926703091643
Max	ENSMUSG00000059436	0.577829325134931	0.853694531487825	0.853694531487825	0.853694531487825	0.300095920620218	0.853694531487825
Tmem219	ENSMUSG00000060538	0.0236697127745139	0.0355045691617709	0.0201177688382032	0.0355045691617709	0.629211154902385	0.629211154902385
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421
Sco1	ENSMUSG00000069844	0.400265374208515	0.400265374208515	0.214037080764325	0.321055621146488	0.148115998140416	0.321055621146488
Nrbf2	ENSMUSG00000075000	0.576973746230334	0.78148726569172	0.211844580334808	0.635533741004424	0.78148726569172	0.78148726569172
AU041133	ENSMUSG00000078435	0.853480389728993	0.853480389728993	0.148115998140416	0.442231101684348	0.294820734456232	0.442231101684348
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321
Zfp703	ENSMUSG00000085795	0.642864324224729	0.926333123228344	0.926333123228344	0.926333123228344	0.45596561163947	0.926333123228344
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517
Med20	ENSMUSG00000092558	0.451840588205062	0.575824878403157	0.454942951775341	0.575824878403157	0.575824878403157	0.575824878403157
Zfp433	ENSMUSG00000096795	0.782117202022501	0.853480389728993	0.254414773803597	0.763244321410791	0.853480389728993	0.853480389728993

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mRNA Splicing - Major Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hnrnpd	ENSMUSG00000000568	0.5155648232968	0.712057867818062	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062
Sf3a1	ENSMUSG00000002129	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Elavl2	ENSMUSG00000008489	0.34578389175364	0.51867583763046	0.640355507848752	0.640355507848752	0.0669218035111213	0.200765410533364
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Cdc5l	ENSMUSG00000023932	0.344663224299303	0.638824656785692	0.509798138101151	0.638824656785692	0.638824656785692	0.638824656785692
Rbm22	ENSMUSG00000024604	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	1	1
Sf3b2	ENSMUSG00000024853	0.400265374208515	0.853480389728993	0.643359829732651	0.853480389728993	0.853480389728993	0.853480389728993
Ybx1	ENSMUSG00000028639	0.852832278580641	0.852832278580641	0.577829325134931	0.852832278580641	0.256271555563967	0.7688146666919
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Wbp11	ENSMUSG00000030216	0.297848640636702	0.893545921910107	0.926333123228344	0.926333123228344	0.7802108304765	0.926333123228344
Pqbp1	ENSMUSG00000031157	0.134789313526392	0.202183970289588	0.093084640707941	0.202183970289588	0.926441990075769	0.926441990075769
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
Hnrnpul1	ENSMUSG00000040725	0.853694531487825	0.853801250889739	0.578396848531894	0.853801250889739	0.853801250889739	0.853801250889739
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125

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mRNA Splicing

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hnrnpd	ENSMUSG00000000568	0.5155648232968	0.712057867818062	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062
Sf3a1	ENSMUSG00000002129	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Elavl2	ENSMUSG00000008489	0.34578389175364	0.51867583763046	0.640355507848752	0.640355507848752	0.0669218035111213	0.200765410533364
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Cdc5l	ENSMUSG00000023932	0.344663224299303	0.638824656785692	0.509798138101151	0.638824656785692	0.638824656785692	0.638824656785692
Rbm22	ENSMUSG00000024604	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	1	1
Sf3b2	ENSMUSG00000024853	0.400265374208515	0.853480389728993	0.643359829732651	0.853480389728993	0.853480389728993	0.853480389728993
Ybx1	ENSMUSG00000028639	0.852832278580641	0.852832278580641	0.577829325134931	0.852832278580641	0.256271555563967	0.7688146666919
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Wbp11	ENSMUSG00000030216	0.297848640636702	0.893545921910107	0.926333123228344	0.926333123228344	0.7802108304765	0.926333123228344
Pqbp1	ENSMUSG00000031157	0.134789313526392	0.202183970289588	0.093084640707941	0.202183970289588	0.926441990075769	0.926441990075769
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
Hnrnpul1	ENSMUSG00000040725	0.853694531487825	0.853801250889739	0.578396848531894	0.853801250889739	0.853801250889739	0.853801250889739
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125

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Metabolism of RNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hnrnpd	ENSMUSG00000000568	0.5155648232968	0.712057867818062	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062
C1d	ENSMUSG00000000581	0.577829325134931	0.866743987702397	0.926658283600152	0.926658283600152	0.454942951775342	0.866743987702397
Sf3a1	ENSMUSG00000002129	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Khsrp	ENSMUSG00000007670	0.25141795904251	0.754253877127531	0.567513221841557	0.778911768167544	0.778911768167544	0.778911768167544
Elavl2	ENSMUSG00000008489	0.34578389175364	0.51867583763046	0.640355507848752	0.640355507848752	0.0669218035111213	0.200765410533364
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Smn1	ENSMUSG00000021645	0.777922216623952	0.777922216623952	0.253294730253594	0.757753700158231	0.505169133438821	0.757753700158231
Pabpc1	ENSMUSG00000022283	0.926003599371282	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404	0.92622377157404
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Cdc5l	ENSMUSG00000023932	0.344663224299303	0.638824656785692	0.509798138101151	0.638824656785692	0.638824656785692	0.638824656785692
Etf1	ENSMUSG00000024360	0.700855417205622	0.773122046545957	0.773122046545957	0.773122046545957	0.346899083932133	0.773122046545957
Riok3	ENSMUSG00000024404	0.342405296020881	0.522566341862834	0.853801250889739	0.853801250889739	0.34837756124189	0.522566341862834
Rbm22	ENSMUSG00000024604	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	1	1
Sf3b2	ENSMUSG00000024853	0.400265374208515	0.853480389728993	0.643359829732651	0.853480389728993	0.853480389728993	0.853480389728993
Ybx1	ENSMUSG00000028639	0.852832278580641	0.852832278580641	0.577829325134931	0.852832278580641	0.256271555563967	0.7688146666919
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Wbp11	ENSMUSG00000030216	0.297848640636702	0.893545921910107	0.926333123228344	0.926333123228344	0.7802108304765	0.926333123228344
Pqbp1	ENSMUSG00000031157	0.134789313526392	0.202183970289588	0.093084640707941	0.202183970289588	0.926441990075769	0.926441990075769
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
Rps16	ENSMUSG00000037563	0.455625354715449	0.683438032073173	0.78148726569172	0.78148726569172	0.454600801949285	0.683438032073173
Smg6	ENSMUSG00000038290	0.299349060054895	0.898047180164686	0.853907737111068	0.926441990075769	0.926441990075769	0.926441990075769
Hnrnpul1	ENSMUSG00000040725	0.853694531487825	0.853801250889739	0.578396848531894	0.853801250889739	0.853801250889739	0.853801250889739
Dcp1b	ENSMUSG00000041477	0.148772260628989	0.223158390943484	0.0936419271039908	0.223158390943484	0.853372965654504	0.853372965654504
Smg7	ENSMUSG00000042772	0.78180291566155	0.78180291566155	0.299349060054895	0.770497594023414	0.513665062682276	0.770497594023414
Patl1	ENSMUSG00000046139	0.643853282854191	0.708323672944427	0.708323672944427	0.708323672944427	0.342026805366747	0.708323672944427
Pom121	ENSMUSG00000053293	0.255530331334266	0.383295497001398	0.209636747299872	0.383295497001398	0.705968934865368	0.705968934865368
Set	ENSMUSG00000054766	0.710208797518812	1	1	1	0.214764523938593	0.64429357181578
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517

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Processing of Capped Intron-Containing Pre-mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hnrnpd	ENSMUSG00000000568	0.5155648232968	0.712057867818062	0.643359829732651	0.712057867818062	0.712057867818062	0.712057867818062
Sf3a1	ENSMUSG00000002129	0.299349060054895	0.593892267963669	0.395928178642446	0.593892267963669	1	1
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Lsm2	ENSMUSG00000007050	0.643853282854191	0.853480389728993	0.400265374208515	0.853480389728993	0.853480389728993	0.853480389728993
Elavl2	ENSMUSG00000008489	0.34578389175364	0.51867583763046	0.640355507848752	0.640355507848752	0.0669218035111213	0.200765410533364
Hnrnpk	ENSMUSG00000021546	0.924987846321933	0.924987846321933	0.294820734456232	0.442231101684348	0.254787123615605	0.442231101684348
Sympk	ENSMUSG00000023118	0.853480389728993	0.926658283600152	0.926658283600152	0.926658283600152	0.780851835278818	0.926658283600152
Cdc5l	ENSMUSG00000023932	0.344663224299303	0.638824656785692	0.509798138101151	0.638824656785692	0.638824656785692	0.638824656785692
Rbm22	ENSMUSG00000024604	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	1	1
Sf3b2	ENSMUSG00000024853	0.400265374208515	0.853480389728993	0.643359829732651	0.853480389728993	0.853480389728993	0.853480389728993
Ybx1	ENSMUSG00000028639	0.852832278580641	0.852832278580641	0.577829325134931	0.852832278580641	0.256271555563967	0.7688146666919
Srsf9	ENSMUSG00000029538	0.926550375688041	0.926550375688041	0.113498953177704	0.34049685953311	0.45596561163947	0.683948417459205
Wbp11	ENSMUSG00000030216	0.297848640636702	0.893545921910107	0.926333123228344	0.926333123228344	0.7802108304765	0.926333123228344
Pqbp1	ENSMUSG00000031157	0.134789313526392	0.202183970289588	0.093084640707941	0.202183970289588	0.926441990075769	0.926441990075769
Srrt	ENSMUSG00000037364	0.345410946355104	0.642366752097095	0.642366752097095	0.642366752097095	0.513026869856283	0.642366752097095
Hnrnpul1	ENSMUSG00000040725	0.853694531487825	0.853801250889739	0.578396848531894	0.853801250889739	0.853801250889739	0.853801250889739
Pom121	ENSMUSG00000053293	0.255530331334266	0.383295497001398	0.209636747299872	0.383295497001398	0.705968934865368	0.705968934865368
Casc3	ENSMUSG00000078676	0.924872384323464	0.92589277149125	0.7048795965722	0.92589277149125	0.92589277149125	0.92589277149125

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Signaling by Nuclear Receptors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Fkbp4	ENSMUSG00000030357	0.342405296020881	0.519791938509652	0.572616808177226	0.572616808177226	0.346527959006435	0.519791938509652
Carm1	ENSMUSG00000032185	0.346527959006435	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Tle3	ENSMUSG00000032280	0.78180291566155	1	0.254787123615605	0.764361370846816	1	1
Gnai2	ENSMUSG00000032562	0.577829325134931	0.926333123228344	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344
Pdk3	ENSMUSG00000035232	0.640355507848752	0.640355507848752	0.297095062262362	0.445642593393544	0.0761127945805735	0.228338383741721
Aldh8a1	ENSMUSG00000037542	0.442941842468822	0.664412763703233	0.167210034333791	0.501630103001373	0.771149274768683	0.771149274768683
Usf2	ENSMUSG00000058239	0.850151080737202	1	0.347639524025037	1	1	1
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421

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Regulation of TP53 Activity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stk11	ENSMUSG00000003068	0.781170242226513	1	0.347639524025037	1	1	1
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Ppp1r13b	ENSMUSG00000021285	0.706831781264721	0.7802108304765	0.778253541606068	0.7802108304765	0.7802108304765	0.7802108304765
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Ccna2	ENSMUSG00000027715	0.782117202022501	0.853480389728993	0.853480389728993	0.853480389728993	0.575536202757516	0.853480389728993
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Brd7	ENSMUSG00000031660	0.710001140920767	0.711034989117171	0.454942951775342	0.711034989117171	0.711034989117171	0.711034989117171
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012
Ppp1r13l	ENSMUSG00000040734	0.290984282074805	0.299349060054896	0.299349060054896	0.299349060054896	0.120545895661628	0.299349060054896
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517

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TP53 Regulates Metabolic Genes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Surf1	ENSMUSG00000015790	0.926333123228344	0.926333123228344	0.514934023620344	0.926333123228344	0.640861491578951	0.926333123228344
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Gls	ENSMUSG00000026103	0.853372965654504	0.853372965654504	0.643359829732651	0.853372965654504	0.5155648232968	0.853372965654504
Cox7b	ENSMUSG00000031231	0.514300775319626	0.771451162979439	0.246478961478169	0.739436884434508	0.7802108304765	0.7802108304765
9630033F20Rik	ENSMUSG00000038028	0.926333123228344	0.926333123228344	0.300095920620218	0.600398061312773	0.400265374208515	0.600398061312773
Sco1	ENSMUSG00000069844	0.400265374208515	0.400265374208515	0.214037080764325	0.321055621146488	0.148115998140416	0.321055621146488

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ESR-mediated signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Calm1	ENSMUSG00000001175	0.706831781264721	0.707899741868332	0.707899741868332	0.707899741868332	0.572616808177226	0.707899741868332
Cdkn1b	ENSMUSG00000003031	0.455625354715449	0.643359829732651	0.638310022345193	0.643359829732651	0.643359829732651	0.643359829732651
Akt2	ENSMUSG00000004056	0.297848640636702	0.853480389728993	0.853480389728993	0.853480389728993	0.853372965654504	0.853480389728993
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Calm3	ENSMUSG00000019370	0.924872384323463	0.924872384323463	0.447621891168214	0.671432836752321	0.120850531362929	0.362551594088787
Myc	ENSMUSG00000022346	0.926550375688041	0.926550375688041	0.926003599371282	0.926550375688041	0.642366752097095	0.926550375688041
Tgfa	ENSMUSG00000029999	0.710001140920767	0.92622377157404	0.92622377157404	0.92622377157404	0.708534948098331	0.92622377157404
Fkbp4	ENSMUSG00000030357	0.342405296020881	0.519791938509652	0.572616808177226	0.572616808177226	0.346527959006435	0.519791938509652
Carm1	ENSMUSG00000032185	0.346527959006435	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Tle3	ENSMUSG00000032280	0.78180291566155	1	0.254787123615605	0.764361370846816	1	1
Gnai2	ENSMUSG00000032562	0.577829325134931	0.926333123228344	0.853694531487825	0.926333123228344	0.926333123228344	0.926333123228344
Usf2	ENSMUSG00000058239	0.850151080737202	1	0.347639524025037	1	1	1
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421

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Chromatin organization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mta1	ENSMUSG00000021144	0.641867098978198	1	1	1	0.926550375688041	1
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Carm1	ENSMUSG00000032185	0.346527959006435	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Phf8	ENSMUSG00000041229	1	1	0.926278508226733	1	0.781645261743309	1
Setd1a	ENSMUSG00000042308	0.711854160331342	0.711854160331342	0.211844580334808	0.635533741004424	0.711240436189781	0.711854160331342
Arid4a	ENSMUSG00000048118	0.347639524025037	0.521459286037555	0.0928059258606269	0.278417777581881	0.852723421673413	0.852723421673413
Msl1	ENSMUSG00000052915	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571	0.642864324224729	0.711650020253571
Mta3	ENSMUSG00000055817	0.853480389728993	0.853480389728993	0.780851835278818	0.853480389728993	0.578396848531894	0.853480389728993
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321

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Chromatin modifying enzymes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mta1	ENSMUSG00000021144	0.641867098978198	1	1	1	0.926550375688041	1
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Rela	ENSMUSG00000024927	0.216214347033995	0.648643041101984	0.853907737111068	0.853907737111068	0.782117202022501	0.853907737111068
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Meaf6	ENSMUSG00000028863	0.852940894477647	1	1	1	0.453225835454267	1
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Carm1	ENSMUSG00000032185	0.346527959006435	0.926550375688041	0.781170242226513	0.926550375688041	0.926550375688041	0.926550375688041
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Phf8	ENSMUSG00000041229	1	1	0.926278508226733	1	0.781645261743309	1
Setd1a	ENSMUSG00000042308	0.711854160331342	0.711854160331342	0.211844580334808	0.635533741004424	0.711240436189781	0.711854160331342
Arid4a	ENSMUSG00000048118	0.347639524025037	0.521459286037555	0.0928059258606269	0.278417777581881	0.852723421673413	0.852723421673413
Msl1	ENSMUSG00000052915	0.577829325134931	0.711650020253571	0.711650020253571	0.711650020253571	0.642864324224729	0.711650020253571
Mta3	ENSMUSG00000055817	0.853480389728993	0.853480389728993	0.780851835278818	0.853480389728993	0.578396848531894	0.853480389728993
Chd4	ENSMUSG00000063870	0.347639524025037	0.771451162979439	0.514300775319626	0.771451162979439	0.926658283600152	0.926658283600152
Hist1h4j	ENSMUSG00000067455	0.564736604446421	0.564736604446421	0.249528554620971	0.564736604446421	0.39335551479284	0.564736604446421
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321

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RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Smarcd1	ENSMUSG00000023018	0.779238691542963	0.926333123228344	0.926333123228344	0.926333123228344	0.711240436189781	0.926333123228344
Csnk2b	ENSMUSG00000024387	0.398829756175299	0.577829325134931	0.294820734456232	0.577829325134931	0.577829325134931	0.577829325134931
Smarcc2	ENSMUSG00000025369	0.779238691542963	0.779238691542963	0.252545530864481	0.757636592593443	0.514934023620344	0.772401035430517
Smarca4	ENSMUSG00000032187	0.295581119060361	0.852065168704833	0.852065168704833	0.852065168704833	0.710416009055326	0.852065168704833
Csnk2a2	ENSMUSG00000046707	0.399548817627028	0.511742979522636	0.511742979522636	0.511742979522636	0.348008842235184	0.511742979522636
Smarcd2	ENSMUSG00000078619	0.120850531362929	0.362551594088788	0.77205234322561	0.846584006881321	0.846584006881321	0.846584006881321

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Intrinsic Pathway for Apoptosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Aven	ENSMUSG00000003604	0.254414773803597	0.381622160705395	0.711034989117171	0.711034989117171	0.180293335960318	0.381622160705395
Ywhah	ENSMUSG00000018965	0.853480389728993	0.853480389728993	0.711240436189781	0.853480389728993	0.400265374208515	0.853480389728993
Ywhae	ENSMUSG00000020849	0.578113371816017	0.710208797518812	0.642366752097095	0.710208797518812	0.710208797518812	0.710208797518812
Ywhaz	ENSMUSG00000022285	0.252545530864481	0.597162263671263	0.638824656785692	0.638824656785692	0.398108175780842	0.597162263671263
Bak1	ENSMUSG00000057789	0.926658283600152	0.926658283600152	0.926550375688041	0.926658283600152	0.926550375688041	0.926658283600152
Mapk3	ENSMUSG00000063065	0.256271555563966	0.384407333345949	0.398829756175299	0.398829756175299	0.25141795904251	0.384407333345949

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Signaling by TGF-beta Receptor Complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ube2m	ENSMUSG00000005575	0.712057867818062	0.926550375688041	0.926550375688041	0.926550375688041	0.21549027811633	0.646470834348991
E2f4	ENSMUSG00000014859	0.578113371816017	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041	0.926550375688041
Smad2	ENSMUSG00000024563	0.573791743469336	0.853049270252403	0.120850531362929	0.362551594088788	0.853049270252403	0.853049270252403
Nedd4l	ENSMUSG00000024589	0.847921313356738	0.847921313356738	0.236337185850514	0.378818296296721	0.252545530864481	0.378818296296721
Ncor2	ENSMUSG00000029478	0.577259514257969	0.782117202022501	0.299349060054895	0.782117202022501	0.782117202022501	0.782117202022501
Fkbp1a	ENSMUSG00000032966	0.577829325134931	0.577829325134931	0.255901190956604	0.577829325134931	0.456305241393103	0.577829325134931
Uba52	ENSMUSG00000090137	1	1	0.346527959006435	0.772401035430517	0.514934023620345	0.772401035430517

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RNA Polymerase II Pre-transcription Events

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Supt6	ENSMUSG00000002052	0.300095920620218	0.900287761860654	0.926333123228344	0.926333123228344	0.78148726569172	0.926333123228344
Polr2a	ENSMUSG00000005198	0.780851835278817	1	0.926550375688041	1	1	1
Ctr9	ENSMUSG00000005609	0.29252580908486	0.853480389728993	0.640355507848752	0.853480389728993	0.853480389728993	0.853480389728993
Taf15	ENSMUSG00000020680	0.299349060054895	0.454600801949285	0.454600801949285	0.454600801949285	0.398829756175299	0.454600801949285
Rtf1	ENSMUSG00000027304	0.293293089483362	0.848280005680805	0.769496350735448	0.848280005680805	0.848280005680805	0.848280005680805
Tceb3	ENSMUSG00000028668	0.300095920620218	0.450143880930327	0.290984282074805	0.450143880930327	0.852065168704833	0.852065168704833
Nelfa	ENSMUSG00000029111	0.642366752097095	0.926333123228344	0.926333123228344	0.926333123228344	0.643359829732651	0.926333123228344
Taf6	ENSMUSG00000036980	0.255901190956604	0.51304020805012	1	1	0.342026805366747	0.51304020805012

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lightblue4

[1] “No significantly overrepresented pathways reported”

lightgreen

PPAR signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Plin4	ENSMUSG00000002831	0.575824878403157	0.643359829732651	0.643359829732651	0.643359829732651	0.146800541856249	0.440401625568746
Plin5	ENSMUSG00000011305	0.000373355180054072	0.00112006554016222	0.576973746230334	0.576973746230334	0.00468160475316412	0.00702240712974618
Lpl	ENSMUSG00000015568	0.00270924971713393	0.00812774915140177	0.0716332429957515	0.0716332429957515	0.0321889748775514	0.0482834623163271
Rxrg	ENSMUSG00000015843	0.214401013708445	0.586687163827674	0.925160045487646	0.925160045487646	0.391124775885116	0.586687163827674
Adipoq	ENSMUSG00000022878	0.177153312234059	0.265729968351088	0.57113445032749	0.57113445032749	0.0331400397096515	0.0994201191289545
Scd1	ENSMUSG00000037071	0.00768144932639892	0.0230443479791968	0.29252580908486	0.29252580908486	0.0325051220296005	0.0487576830444007
Fabp4	ENSMUSG00000062515	0.115651627788147	0.173477441682221	0.781170242226513	0.781170242226513	0.0238002551499929	0.0714007654499788

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Regulation of lipolysis in adipocytes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tshr	ENSMUSG00000020963	0.024062085667391	0.0360931285010865	0.0439832496172286	0.0439832496172286	0.0108268982515581	0.0324806947546744
Adrb3	ENSMUSG00000031489	0.0761127945805736	0.144637845807821	0.252545530864481	0.252545530864481	0.096425230538547	0.144637845807821
Irs3	ENSMUSG00000047182	0.0027394024069996	0.00821820722099879	0.51270683838022	0.51270683838022	0.0222505050945549	0.0333757576418323
Fabp4	ENSMUSG00000062515	0.115651627788147	0.173477441682221	0.781170242226513	0.781170242226513	0.0238002551499929	0.0714007654499788

Download data as csv

Metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pemt	ENSMUSG00000000301	0.256271555563966	0.384407333345949	0.513665062682276	0.513665062682276	0.146141353215796	0.384407333345949
Prkar2b	ENSMUSG00000002997	0.18064054691103	0.18064054691103	0.0761127945805735	0.11416919187086	0.0241933715424143	0.0725801146272428
Cav1	ENSMUSG00000007655	0.643853282854191	0.643853282854191	0.213307944885796	0.324321520550991	0.216214347033994	0.324321520550991
Lpl	ENSMUSG00000015568	0.00270924971713393	0.00812774915140177	0.0716332429957515	0.0716332429957515	0.0321889748775514	0.0482834623163271
Adipoq	ENSMUSG00000022878	0.177153312234059	0.265729968351088	0.57113445032749	0.57113445032749	0.0331400397096515	0.0994201191289545
Rbp4	ENSMUSG00000024990	0.0331400397096515	0.0497100595644772	0.0331400397096515	0.0497100595644772	0.399548817627028	0.399548817627028
Cyp2e1	ENSMUSG00000025479	0.0969812105731562	0.0969812105731562	0.0964252305385473	0.0969812105731562	0.0328221470541517	0.0969812105731562
Adhfe1	ENSMUSG00000025911	0.148115998140416	0.321055621146488	0.511742979522636	0.511742979522636	0.214037080764326	0.321055621146488
Marc1	ENSMUSG00000026621	0.0417377002086289	0.0885635751539413	0.0967032506702096	0.0967032506702096	0.0590423834359609	0.0885635751539413
Adal	ENSMUSG00000027259	0.00477055016690543	0.0143116505007163	0.711650020253571	0.711650020253571	0.0763619660358786	0.114542949053818
Car3	ENSMUSG00000027559	0.298599969973533	0.447899954960299	0.709375484777034	0.709375484777034	0.094755898098955	0.284267694296865
Fah	ENSMUSG00000030630	5.46967066778584e-05	0.000164090120033575	0.0113089139751576	0.0169633709627364	0.51270683838022	0.51270683838022
Car5b	ENSMUSG00000031373	0.0075577836449293	0.0226733509347879	0.119631084167592	0.119631084167592	0.0436072256433733	0.06541083846506
Nnmt	ENSMUSG00000032271	0.11810342389482	0.11810342389482	0.0104326641569827	0.0312979924709482	0.0321889748775514	0.0482834623163271
Folr2	ENSMUSG00000032725	0.120850531362929	0.178901132102685	0.118714930081337	0.178901132102685	0.178901132102685	0.178901132102685
Cdo1	ENSMUSG00000033022	0.0592616003460513	0.0888924005190769	0.398829756175299	0.398829756175299	0.024062085667391	0.0721862570021729
B3galt2	ENSMUSG00000033849	0.0163700297194362	0.0491100891583087	0.179945789077372	0.179945789077372	0.0441715176243983	0.0662572764365975
Thrsp	ENSMUSG00000035686	0.0238002551499929	0.0357003827249894	0.146800541856249	0.146800541856249	0.0073134885581712	0.0219404656745136
Scd1	ENSMUSG00000037071	0.00768144932639892	0.0230443479791968	0.29252580908486	0.29252580908486	0.0325051220296005	0.0487576830444007
Hs3st6	ENSMUSG00000039628	0.0236697127745139	0.0355045691617709	0.00737418180192506	0.0221225454057752	0.0950342596054052	0.0950342596054052
Rimklb	ENSMUSG00000040649	0.391124775885116	0.51270683838022	0.51270683838022	0.51270683838022	0.212211059210313	0.51270683838022
Pcca	ENSMUSG00000041650	0.148772260628989	0.223158390943484	0.392985378348026	0.392985378348026	0.0969812105731562	0.223158390943484
Fabp4	ENSMUSG00000062515	0.115651627788147	0.173477441682221	0.781170242226513	0.781170242226513	0.0238002551499929	0.0714007654499788
Glyat	ENSMUSG00000063683	0.213672724643677	0.64101817393103	0.643606811957488	0.643606811957488	0.643606811957488	0.643606811957488
Aldh3b2	ENSMUSG00000075296	0.148772260628989	0.383851786434906	0.455625354715449	0.455625354715449	0.255901190956604	0.383851786434906

Download data as csv

lightskyblue2

[1] “No significantly overrepresented pathways reported”

linen

[1] “No significantly overrepresented pathways reported”

magenta2

[1] “No significantly overrepresented pathways reported”

magenta3

EGFR tyrosine kinase inhibitor resistance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Axl	ENSMUSG00000002602	0.211844580334808	0.507888175712984	0.338592117141989	0.507888175712984	0.853801250889739	0.853801250889739
Stat3	ENSMUSG00000004040	0.148115998140415	0.257789055318653	0.171859370212435	0.257789055318653	0.395196379647461	0.395196379647461
Erbb3	ENSMUSG00000018166	0.7802108304765	1	0.575824878403157	1	1	1
Egfr	ENSMUSG00000020122	0.397384062266614	0.7733472349452	0.5155648232968	0.7733472349452	0.926550375688041	0.926550375688041
Nf1	ENSMUSG00000020716	0.853694531487825	0.853694531487825	0.711240436189781	0.853694531487825	0.299349060054895	0.853694531487825
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Il6ra	ENSMUSG00000027947	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769	0.514934023620344	0.926441990075769
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Pdgfd	ENSMUSG00000032006	0.853694531487825	0.853694531487825	0.781645261743309	0.853694531487825	0.853694531487825	0.853694531487825
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Shc1	ENSMUSG00000042626	0.213307944885796	0.578396848531894	0.578396848531894	0.578396848531894	0.514934023620345	0.578396848531894

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Insulin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tsc2	ENSMUSG00000002496	0.454600801949285	0.772401035430517	0.853801250889739	0.853801250889739	0.514934023620345	0.772401035430517
Crkl	ENSMUSG00000006134	0.643359829732651	0.926550375688041	0.926550375688041	0.926550375688041	0.643853282854191	0.926550375688041
Mapk9	ENSMUSG00000020366	0.575824878403157	0.852065168704833	0.852065168704833	0.852065168704833	0.576112968612194	0.852065168704833
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Rptor	ENSMUSG00000025583	0.853372965654504	0.92622377157404	0.92622377157404	0.92622377157404	0.297848640636702	0.893545921910107
Tsc1	ENSMUSG00000026812	0.570836132666921	0.852832278580641	0.852832278580641	0.852832278580641	0.293293089483362	0.852832278580641
Mknk1	ENSMUSG00000028708	0.853049270252403	0.853049270252403	0.400265374208515	0.600398061312773	0.115037265385284	0.345111796155853
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Phka2	ENSMUSG00000031295	0.0588232673880149	0.176469802164045	0.514934023620344	0.772401035430517	0.78180291566155	0.78180291566155
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Prkar2a	ENSMUSG00000032601	0.779238691542963	0.779238691542963	0.708323672944427	0.779238691542963	0.514934023620345	0.779238691542963
Inppl1	ENSMUSG00000032737	1	1	0.643359829732651	1	0.710208797518812	1
Ptprf	ENSMUSG00000033295	0.782117202022501	0.782117202022501	0.344663224299303	0.782117202022501	0.782117202022501	0.782117202022501
Shc1	ENSMUSG00000042626	0.213307944885796	0.578396848531894	0.578396848531894	0.578396848531894	0.514934023620345	0.578396848531894
Ppp1r3a	ENSMUSG00000042717	0.111648556719408	0.167472835079113	0.705534647520136	0.705534647520136	0.0376925291244404	0.113077587373321

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Thermogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tsc2	ENSMUSG00000002496	0.454600801949285	0.772401035430517	0.853801250889739	0.853801250889739	0.514934023620345	0.772401035430517
Adcy9	ENSMUSG00000005580	0.852065168704833	0.926550375688041	0.926550375688041	0.926550375688041	0.511097249598474	0.926550375688041
Acsl6	ENSMUSG00000020333	0.216214347033995	0.648643041101984	0.712057867818062	0.712057867818062	0.712057867818062	0.712057867818062
Adcy3	ENSMUSG00000020654	0.0763619660358786	0.21549027811633	0.17924968721805	0.21549027811633	0.21549027811633	0.21549027811633
Uqcrb	ENSMUSG00000021520	0.058823267388015	0.176469802164045	0.926658283600152	0.926658283600152	0.120545895661627	0.180818843492441
Ndufs6	ENSMUSG00000021606	0.450794830295118	0.450794830295118	0.161774914569557	0.383851786434906	0.255901190956604	0.383851786434906
Ndufb4	ENSMUSG00000022820	0.78180291566155	0.78180291566155	0.346527959006435	0.519791938509652	0.300095920620218	0.519791938509652
Ndufv2	ENSMUSG00000024099	0.926658283600152	0.926658283600152	0.253294730253594	0.759884190760783	0.5155648232968	0.7733472349452
Rptor	ENSMUSG00000025583	0.853372965654504	0.92622377157404	0.92622377157404	0.92622377157404	0.297848640636702	0.893545921910107
Cox20	ENSMUSG00000026500	0.711034989117171	0.711034989117171	0.710416009055326	0.711034989117171	0.118714930081337	0.35614479024401
Tsc1	ENSMUSG00000026812	0.570836132666921	0.852832278580641	0.852832278580641	0.852832278580641	0.293293089483362	0.852832278580641
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Atp5h	ENSMUSG00000034566	0.57466664340579	0.57466664340579	0.388491809581663	0.57466664340579	0.300095920620218	0.57466664340579
Cox17	ENSMUSG00000046516	0.779238691542963	0.779238691542963	0.338592117141989	0.519791938509652	0.346527959006435	0.519791938509652
Mapk14	ENSMUSG00000053436	0.92622377157404	0.92622377157404	0.782117202022501	0.92622377157404	0.213307944885796	0.639923834657388
Zfp516	ENSMUSG00000058881	0.342026805366747	0.767614469283954	0.777922216623952	0.777922216623952	0.511742979522636	0.767614469283954
Uqcrh	ENSMUSG00000063882	0.440372926628091	0.440372926628091	0.0642056836831393	0.192617051049418	0.338592117141989	0.440372926628091
mt-Co2	ENSMUSG00000064354	0.577259514257969	0.926441990075769	0.926441990075769	0.926441990075769	0.642366752097095	0.926441990075769
Arid1b	ENSMUSG00000069729	0.454942951775341	0.454942951775341	0.452880492349546	0.454942951775341	0.398108175780842	0.454942951775341

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Axon guidance

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sema6a	ENSMUSG00000019647	0.782117202022501	0.782117202022501	0.297095062262363	0.782117202022501	0.782117202022501	0.782117202022501
Ptch1	ENSMUSG00000021466	0.57466664340579	0.853049270252403	0.853049270252403	0.853049270252403	0.211844580334808	0.635533741004424
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Abl1	ENSMUSG00000026842	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501	0.643359829732651	0.782117202022501
Ephb2	ENSMUSG00000028664	0.299349060054895	0.599323226440542	0.399548817627028	0.599323226440542	0.852832278580641	0.852832278580641
Plxna4	ENSMUSG00000029765	0.515249728559994	0.772874592839992	0.515249728559994	0.772874592839992	0.853694531487825	0.853694531487825
Plxna1	ENSMUSG00000030084	0.342026805366747	0.51304020805012	0.926550375688041	0.926550375688041	0.179945789077372	0.51304020805012
Plxna3	ENSMUSG00000031398	0.7802108304765	0.926658283600152	0.926658283600152	0.926658283600152	0.57466664340579	0.926658283600152
Nfatc3	ENSMUSG00000031902	0.575536202757516	0.78180291566155	0.78180291566155	0.78180291566155	0.300095920620218	0.78180291566155
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Ptpn11	ENSMUSG00000043733	0.256271555563966	0.384407333345949	0.25141795904251	0.384407333345949	0.7802108304765	0.7802108304765
Epha3	ENSMUSG00000052504	0.853694531487825	0.853694531487825	0.643359829732651	0.853694531487825	0.513026869856283	0.853694531487825
Slit3	ENSMUSG00000056427	0.454942951775341	0.577259514257969	0.514934023620345	0.577259514257969	0.577259514257969	0.577259514257969
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1
Bmpr2	ENSMUSG00000067336	0.216214347033995	0.255901190956604	0.0328221470541517	0.0984664411624552	0.255901190956604	0.255901190956604

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Ubiquitin mediated proteolysis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Keap1	ENSMUSG00000003308	0.0967032506702098	0.220694657318384	0.14712977154559	0.220694657318384	0.708534948098331	0.708534948098331
Ube2i	ENSMUSG00000015120	0.346899083932133	0.781170242226513	0.781170242226513	0.781170242226513	0.781170242226513	0.781170242226513
Rhobtb1	ENSMUSG00000019944	0.178901132102685	0.346527959006435	0.338592117141989	0.346527959006435	0.346527959006435	0.346527959006435
Btrc	ENSMUSG00000025217	0.216214347033995	0.648643041101984	1	1	0.926658283600152	1
Huwe1	ENSMUSG00000025261	0.779238691542963	0.853801250889739	0.853801250889739	0.853801250889739	0.204424977646738	0.613274932940215
Anapc2	ENSMUSG00000026965	0.926003599371281	0.926003599371281	0.343537039781257	0.515305559671886	0.11993617140438	0.359808514213139
Ubox5	ENSMUSG00000027300	0.297472133192261	0.446208199788392	0.92550091578426	0.92550091578426	0.0292313579578282	0.0876940738734845
Anapc4	ENSMUSG00000029176	0.643853282854191	0.926333123228344	0.0969812105731562	0.290943631719469	0.926333123228344	0.926333123228344
Herc3	ENSMUSG00000029804	0.640861491578951	0.926441990075769	0.926441990075769	0.926441990075769	0.643359829732651	0.926441990075769
Herc2	ENSMUSG00000030451	0.300095920620218	0.450143880930327	0.926333123228344	0.926333123228344	0.255901190956604	0.450143880930327
Nedd4	ENSMUSG00000032216	1	1	0.926003599371282	1	0.511742979522636	1
Pias1	ENSMUSG00000032405	0.180293335960318	0.256271555563966	0.256271555563966	0.256271555563966	0.119631084167592	0.256271555563966
Ubr5	ENSMUSG00000037487	0.577829325134931	0.577829325134931	0.178901132102685	0.319961917328694	0.213307944885796	0.319961917328694

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Non-alcoholic fatty liver disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mapk9	ENSMUSG00000020366	0.575824878403157	0.852065168704833	0.852065168704833	0.852065168704833	0.576112968612194	0.852065168704833
Ern1	ENSMUSG00000020715	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152	0.642864324224729	0.926658283600152
Uqcrb	ENSMUSG00000021520	0.058823267388015	0.176469802164045	0.926658283600152	0.926658283600152	0.120545895661627	0.180818843492441
Ndufs6	ENSMUSG00000021606	0.450794830295118	0.450794830295118	0.161774914569557	0.383851786434906	0.255901190956604	0.383851786434906
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Ndufb4	ENSMUSG00000022820	0.78180291566155	0.78180291566155	0.346527959006435	0.519791938509652	0.300095920620218	0.519791938509652
Ndufv2	ENSMUSG00000024099	0.926658283600152	0.926658283600152	0.253294730253594	0.759884190760783	0.5155648232968	0.7733472349452
Il6ra	ENSMUSG00000027947	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769	0.514934023620344	0.926441990075769
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Mlxip	ENSMUSG00000038342	0.775217051297351	0.775217051297351	0.213307944885796	0.593892267963669	0.395928178642446	0.593892267963669
Lepr	ENSMUSG00000057722	0.216214347033995	0.324321520550992	0.781170242226513	0.781170242226513	0.177853449259986	0.324321520550992
Uqcrh	ENSMUSG00000063882	0.440372926628091	0.440372926628091	0.0642056836831393	0.192617051049418	0.338592117141989	0.440372926628091
mt-Co2	ENSMUSG00000064354	0.577259514257969	0.926441990075769	0.926441990075769	0.926441990075769	0.642366752097095	0.926441990075769

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Growth hormone synthesis, secretion and action

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat3	ENSMUSG00000004040	0.148115998140415	0.257789055318653	0.171859370212435	0.257789055318653	0.395196379647461	0.395196379647461
Adcy9	ENSMUSG00000005580	0.852065168704833	0.926550375688041	0.926550375688041	0.926550375688041	0.511097249598474	0.926550375688041
Crkl	ENSMUSG00000006134	0.643359829732651	0.926550375688041	0.926550375688041	0.926550375688041	0.643853282854191	0.926550375688041
Mapk9	ENSMUSG00000020366	0.575824878403157	0.852065168704833	0.852065168704833	0.852065168704833	0.576112968612194	0.852065168704833
Adcy3	ENSMUSG00000020654	0.0763619660358786	0.21549027811633	0.17924968721805	0.21549027811633	0.21549027811633	0.21549027811633
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Shc1	ENSMUSG00000042626	0.213307944885796	0.578396848531894	0.578396848531894	0.578396848531894	0.514934023620345	0.578396848531894
Itpr3	ENSMUSG00000042644	0.294820734456232	0.442231101684348	0.5155648232968	0.5155648232968	0.17924968721805	0.442231101684348
Mapk14	ENSMUSG00000053436	0.92622377157404	0.92622377157404	0.782117202022501	0.92622377157404	0.213307944885796	0.639923834657388

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Autophagy - animal

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tsc2	ENSMUSG00000002496	0.454600801949285	0.772401035430517	0.853801250889739	0.853801250889739	0.514934023620345	0.772401035430517
Ulk2	ENSMUSG00000004798	0.926658283600152	0.926658283600152	0.711034989117171	0.926658283600152	0.399548817627028	0.926658283600152
Eif2ak4	ENSMUSG00000005102	0.255530331334266	0.383295497001398	1	1	0.252920381501206	0.383295497001398
Mapk9	ENSMUSG00000020366	0.575824878403157	0.852065168704833	0.852065168704833	0.852065168704833	0.576112968612194	0.852065168704833
Ern1	ENSMUSG00000020715	0.926658283600152	0.926658283600152	0.853907737111068	0.926658283600152	0.642864324224729	0.926658283600152
Rptor	ENSMUSG00000025583	0.853372965654504	0.92622377157404	0.92622377157404	0.92622377157404	0.297848640636702	0.893545921910107
Tsc1	ENSMUSG00000026812	0.570836132666921	0.852832278580641	0.852832278580641	0.852832278580641	0.293293089483362	0.852832278580641
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Pik3c3	ENSMUSG00000033628	0.640861491578951	0.778911768167544	0.778911768167544	0.778911768167544	0.640861491578951	0.778911768167544
Ambra1	ENSMUSG00000040506	0.641867098978198	0.926658283600152	0.926658283600152	0.926658283600152	0.298599969973533	0.895799909920599
5430435G22Rik	ENSMUSG00000052688	0.044926265292481	0.107449864493627	0.346899083932133	0.346899083932133	0.0716332429957516	0.107449864493627

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ErbB signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Crkl	ENSMUSG00000006134	0.643359829732651	0.926550375688041	0.926550375688041	0.926550375688041	0.643853282854191	0.926550375688041
Erbb3	ENSMUSG00000018166	0.7802108304765	1	0.575824878403157	1	1	1
Egfr	ENSMUSG00000020122	0.397384062266614	0.7733472349452	0.5155648232968	0.7733472349452	0.926550375688041	0.926550375688041
Mapk9	ENSMUSG00000020366	0.575824878403157	0.852065168704833	0.852065168704833	0.852065168704833	0.576112968612194	0.852065168704833
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Abl1	ENSMUSG00000026842	0.575824878403157	0.782117202022501	0.782117202022501	0.782117202022501	0.643359829732651	0.782117202022501
Mtor	ENSMUSG00000028991	0.343537039781257	0.515305559671886	0.853907737111068	0.853907737111068	0.253294730253595	0.515305559671886
Pik3cb	ENSMUSG00000032462	1	1	0.853907737111068	1	0.853694531487825	1
Shc1	ENSMUSG00000042626	0.213307944885796	0.578396848531894	0.578396848531894	0.578396848531894	0.514934023620345	0.578396848531894

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Interleukin-6 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Stat3	ENSMUSG00000004040	0.148115998140415	0.257789055318653	0.171859370212435	0.257789055318653	0.395196379647461	0.395196379647461
Il6st	ENSMUSG00000021756	0.578113371816017	0.867170057724026	0.926658283600152	0.926658283600152	0.348008842235184	0.867170057724026
Il6ra	ENSMUSG00000027947	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769	0.514934023620344	0.926441990075769
Tyk2	ENSMUSG00000032175	0.453225835454266	0.45596561163947	0.45596561163947	0.45596561163947	0.297095062262362	0.45596561163947
Ptpn11	ENSMUSG00000043733	0.256271555563966	0.384407333345949	0.25141795904251	0.384407333345949	0.7802108304765	0.7802108304765

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NRAGE signals death through JNK

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Arhgef18	ENSMUSG00000004568	0.635703516568382	0.635703516568382	0.514934023620345	0.635703516568382	0.0969812105731563	0.290943631719469
Abr	ENSMUSG00000017631	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Rasgrf2	ENSMUSG00000021708	0.711445446052875	0.781011212316137	0.347639524025037	0.781011212316137	0.781011212316137	0.781011212316137
Arhgef2	ENSMUSG00000028059	0.710416009055326	0.710416009055326	0.146141353215796	0.219212029823694	0.144820068500793	0.219212029823694
Arhgef19	ENSMUSG00000028919	0.57113445032749	0.706831781264722	0.142165951159432	0.426497853478296	0.706831781264722	0.706831781264722
Arhgef16	ENSMUSG00000029032	0.711650020253571	0.853480389728993	0.514934023620345	0.853480389728993	0.853480389728993	0.853480389728993
Arhgef7	ENSMUSG00000031511	0.214764523938594	0.644293571815781	1	1	0.511742979522636	0.767614469283954
Arhgef5	ENSMUSG00000033542	0.92550091578426	0.92550091578426	0.780049698709835	0.92550091578426	0.709793037667153	0.92550091578426
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1

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MAPK1 (ERK2) activation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il6st	ENSMUSG00000021756	0.578113371816017	0.867170057724026	0.926658283600152	0.926658283600152	0.348008842235184	0.867170057724026
Il6ra	ENSMUSG00000027947	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769	0.514934023620344	0.926441990075769
Tyk2	ENSMUSG00000032175	0.453225835454266	0.45596561163947	0.45596561163947	0.45596561163947	0.297095062262362	0.45596561163947
Ptpn11	ENSMUSG00000043733	0.256271555563966	0.384407333345949	0.25141795904251	0.384407333345949	0.7802108304765	0.7802108304765

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MAPK3 (ERK1) activation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il6st	ENSMUSG00000021756	0.578113371816017	0.867170057724026	0.926658283600152	0.926658283600152	0.348008842235184	0.867170057724026
Il6ra	ENSMUSG00000027947	0.782117202022501	0.926441990075769	0.926441990075769	0.926441990075769	0.514934023620344	0.926441990075769
Tyk2	ENSMUSG00000032175	0.453225835454266	0.45596561163947	0.45596561163947	0.45596561163947	0.297095062262362	0.45596561163947
Ptpn11	ENSMUSG00000043733	0.256271555563966	0.384407333345949	0.25141795904251	0.384407333345949	0.7802108304765	0.7802108304765

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Cell death signalling via NRAGE, NRIF and NADE

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Arhgef18	ENSMUSG00000004568	0.635703516568382	0.635703516568382	0.514934023620345	0.635703516568382	0.0969812105731563	0.290943631719469
Abr	ENSMUSG00000017631	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Psen1	ENSMUSG00000019969	0.398108175780843	0.597162263671265	0.776919261684345	0.776919261684345	0.17924968721805	0.537749061654149
Rasgrf2	ENSMUSG00000021708	0.711445446052875	0.781011212316137	0.347639524025037	0.781011212316137	0.781011212316137	0.781011212316137
Arhgef2	ENSMUSG00000028059	0.710416009055326	0.710416009055326	0.146141353215796	0.219212029823694	0.144820068500793	0.219212029823694
Arhgef19	ENSMUSG00000028919	0.57113445032749	0.706831781264722	0.142165951159432	0.426497853478296	0.706831781264722	0.706831781264722
Arhgef16	ENSMUSG00000029032	0.711650020253571	0.853480389728993	0.514934023620345	0.853480389728993	0.853480389728993	0.853480389728993
Arhgef7	ENSMUSG00000031511	0.214764523938594	0.644293571815781	1	1	0.511742979522636	0.767614469283954
Arhgef5	ENSMUSG00000033542	0.92550091578426	0.92550091578426	0.780049698709835	0.92550091578426	0.709793037667153	0.92550091578426
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1

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CRMPs in Sema3A signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gsk3b	ENSMUSG00000022812	0.92589277149125	0.92589277149125	0.852832278580641	0.92589277149125	0.344663224299303	0.92589277149125
Dpysl3	ENSMUSG00000024501	0.575246939700399	0.850608132982798	0.850608132982798	0.850608132982798	0.343160411648939	0.850608132982798
Plxna4	ENSMUSG00000029765	0.515249728559994	0.772874592839992	0.515249728559994	0.772874592839992	0.853694531487825	0.853694531487825
Plxna1	ENSMUSG00000030084	0.342026805366747	0.51304020805012	0.926550375688041	0.926550375688041	0.179945789077372	0.51304020805012
Plxna3	ENSMUSG00000031398	0.7802108304765	0.926658283600152	0.926658283600152	0.926658283600152	0.57466664340579	0.926658283600152

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G alpha (12/13) signalling events

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Arhgef18	ENSMUSG00000004568	0.635703516568382	0.635703516568382	0.514934023620345	0.635703516568382	0.0969812105731563	0.290943631719469
Abr	ENSMUSG00000017631	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Rasgrf2	ENSMUSG00000021708	0.711445446052875	0.781011212316137	0.347639524025037	0.781011212316137	0.781011212316137	0.781011212316137
Arhgef2	ENSMUSG00000028059	0.710416009055326	0.710416009055326	0.146141353215796	0.219212029823694	0.144820068500793	0.219212029823694
Arhgef19	ENSMUSG00000028919	0.57113445032749	0.706831781264722	0.142165951159432	0.426497853478296	0.706831781264722	0.706831781264722
Arhgef16	ENSMUSG00000029032	0.711650020253571	0.853480389728993	0.514934023620345	0.853480389728993	0.853480389728993	0.853480389728993
Gnb1	ENSMUSG00000029064	0.514934023620345	0.514934023620345	0.347639524025037	0.514934023620345	0.455625354715449	0.514934023620345
Arhgef7	ENSMUSG00000031511	0.214764523938594	0.644293571815781	1	1	0.511742979522636	0.767614469283954
Arhgef5	ENSMUSG00000033542	0.92550091578426	0.92550091578426	0.780049698709835	0.92550091578426	0.709793037667153	0.92550091578426
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1

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SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tln1	ENSMUSG00000028465	0.397384062266614	0.7733472349452	0.853372965654504	0.853372965654504	0.5155648232968	0.7733472349452
Plxna4	ENSMUSG00000029765	0.515249728559994	0.772874592839992	0.515249728559994	0.772874592839992	0.853694531487825	0.853694531487825
Plxna1	ENSMUSG00000030084	0.342026805366747	0.51304020805012	0.926550375688041	0.926550375688041	0.179945789077372	0.51304020805012
Plxna3	ENSMUSG00000031398	0.7802108304765	0.926658283600152	0.926658283600152	0.926658283600152	0.57466664340579	0.926658283600152

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Death Receptor Signalling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Arhgef18	ENSMUSG00000004568	0.635703516568382	0.635703516568382	0.514934023620345	0.635703516568382	0.0969812105731563	0.290943631719469
Abr	ENSMUSG00000017631	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Psen1	ENSMUSG00000019969	0.398108175780843	0.597162263671265	0.776919261684345	0.776919261684345	0.17924968721805	0.537749061654149
Rasgrf2	ENSMUSG00000021708	0.711445446052875	0.781011212316137	0.347639524025037	0.781011212316137	0.781011212316137	0.781011212316137
Rbck1	ENSMUSG00000027466	0.255901190956604	0.453570536021945	0.452880492349546	0.453570536021945	0.453570536021945	0.453570536021945
Arhgef2	ENSMUSG00000028059	0.710416009055326	0.710416009055326	0.146141353215796	0.219212029823694	0.144820068500793	0.219212029823694
Arhgef19	ENSMUSG00000028919	0.57113445032749	0.706831781264722	0.142165951159432	0.426497853478296	0.706831781264722	0.706831781264722
Arhgef16	ENSMUSG00000029032	0.711650020253571	0.853480389728993	0.514934023620345	0.853480389728993	0.853480389728993	0.853480389728993
Arhgef7	ENSMUSG00000031511	0.214764523938594	0.644293571815781	1	1	0.511742979522636	0.767614469283954
Smpd3	ENSMUSG00000031906	0.118409250205154	0.355227750615461	0.391498225369152	0.587247338053727	0.926003599371282	0.926003599371282
Arhgef5	ENSMUSG00000033542	0.92550091578426	0.92550091578426	0.780049698709835	0.92550091578426	0.709793037667153	0.92550091578426
Otud7b	ENSMUSG00000038495	0.400265374208515	0.578113371816017	0.578113371816017	0.578113371816017	0.514934023620345	0.578113371816017
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1

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p75 NTR receptor-mediated signalling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Arhgef18	ENSMUSG00000004568	0.635703516568382	0.635703516568382	0.514934023620345	0.635703516568382	0.0969812105731563	0.290943631719469
Abr	ENSMUSG00000017631	0.513665062682276	0.926441990075769	0.926441990075769	0.926441990075769	0.92622377157404	0.926441990075769
Psen1	ENSMUSG00000019969	0.398108175780843	0.597162263671265	0.776919261684345	0.776919261684345	0.17924968721805	0.537749061654149
Rasgrf2	ENSMUSG00000021708	0.711445446052875	0.781011212316137	0.347639524025037	0.781011212316137	0.781011212316137	0.781011212316137
Arhgef2	ENSMUSG00000028059	0.710416009055326	0.710416009055326	0.146141353215796	0.219212029823694	0.144820068500793	0.219212029823694
Arhgef19	ENSMUSG00000028919	0.57113445032749	0.706831781264722	0.142165951159432	0.426497853478296	0.706831781264722	0.706831781264722
Arhgef16	ENSMUSG00000029032	0.711650020253571	0.853480389728993	0.514934023620345	0.853480389728993	0.853480389728993	0.853480389728993
Arhgef7	ENSMUSG00000031511	0.214764523938594	0.644293571815781	1	1	0.511742979522636	0.767614469283954
Arhgef5	ENSMUSG00000033542	0.92550091578426	0.92550091578426	0.780049698709835	0.92550091578426	0.709793037667153	0.92550091578426
Arhgef12	ENSMUSG00000059495	1	1	0.853480389728993	1	0.5155648232968	1

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mediumpurple1

[1] “No significantly overrepresented pathways reported”

mediumpurple3

[1] “No significantly overrepresented pathways reported”

mistyrose

Assembly of collagen fibrils and other multimeric structures

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a3	ENSMUSG00000004098	0.578396848531894	0.712057867818062	0.179945789077372	0.539837367232115	0.712057867818062	0.712057867818062
Lox	ENSMUSG00000024529	0.295581119060361	0.295581119060361	0.178901132102684	0.268351698154027	0.177153312234059	0.268351698154027
Col27a1	ENSMUSG00000045672	0.399548817627028	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Cardiac conduction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Npr2	ENSMUSG00000028469	0.853694531487825	0.853694531487825	0.0443599545252853	0.133079863575856	0.576973746230334	0.853694531487825
Scn7a	ENSMUSG00000034810	0.576112968612194	0.92622377157404	0.643359829732651	0.92622377157404	0.92622377157404	0.92622377157404
Scn9a	ENSMUSG00000075316	1	1	0.513346277289108	0.770019415933663	0.254041925545275	0.762125776635824

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Collagen formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a3	ENSMUSG00000004098	0.578396848531894	0.712057867818062	0.179945789077372	0.539837367232115	0.712057867818062	0.712057867818062
Lox	ENSMUSG00000024529	0.295581119060361	0.295581119060361	0.178901132102684	0.268351698154027	0.177153312234059	0.268351698154027
Col27a1	ENSMUSG00000045672	0.399548817627028	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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MET activates PTK2 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a3	ENSMUSG00000004098	0.578396848531894	0.712057867818062	0.179945789077372	0.539837367232115	0.712057867818062	0.712057867818062
Col27a1	ENSMUSG00000045672	0.399548817627028	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Phase 0 - rapid depolarisation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Scn7a	ENSMUSG00000034810	0.576112968612194	0.92622377157404	0.643359829732651	0.92622377157404	0.92622377157404	0.92622377157404
Scn9a	ENSMUSG00000075316	1	1	0.513346277289108	0.770019415933663	0.254041925545275	0.762125776635824

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Collagen chain trimerization

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a3	ENSMUSG00000004098	0.578396848531894	0.712057867818062	0.179945789077372	0.539837367232115	0.712057867818062	0.712057867818062
Col27a1	ENSMUSG00000045672	0.399548817627028	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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MET promotes cell motility

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Col5a3	ENSMUSG00000004098	0.578396848531894	0.712057867818062	0.179945789077372	0.539837367232115	0.712057867818062	0.712057867818062
Col27a1	ENSMUSG00000045672	0.399548817627028	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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moccasin

Wnt signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lgr5	ENSMUSG00000020140	0.711240436189781	0.711240436189781	0.177853449259986	0.533560347779958	0.704220158648919	0.711240436189781
Csnk1e	ENSMUSG00000022433	0.853694531487825	0.853694531487825	0.78148726569172	0.853694531487825	0.576112968612194	0.853694531487825
Tle2	ENSMUSG00000034771	0.643359829732651	0.926003599371281	0.926003599371281	0.926003599371281	0.852504981253341	0.926003599371281
Znrf3	ENSMUSG00000041961	0.346527959006435	0.577829325134931	0.399548817627028	0.577829325134931	0.577829325134931	0.577829325134931

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ATP sensitive Potassium channels

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Abcc8	ENSMUSG00000040136	0.926550375688041	0.926550375688041	0.712057867818062	0.926550375688041	0.853372965654504	0.926550375688041
Kcnj11	ENSMUSG00000096146	0.926333123228344	0.926333123228344	0.853372965654504	0.926333123228344	0.399548817627028	0.926333123228344

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oldlace

Protein processing in endoplasmic reticulum

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hsph1	ENSMUSG00000029657	0.0325051220296005	0.0975153660888015	1	1	1	1
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Longevity regulating pathway - multiple species

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Legionellosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Antigen processing and presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Toxoplasmosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Spliceosome

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Estrogen signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Measles

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Lipid and atherosclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Prion disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Endocytosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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MAPK signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Attenuation phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Regulation of HSF1-mediated heat shock response

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hsph1	ENSMUSG00000029657	0.0325051220296005	0.0975153660888015	1	1	1	1
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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HSF1-dependent transactivation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Cellular response to heat stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hsph1	ENSMUSG00000029657	0.0325051220296005	0.0975153660888015	1	1	1	1
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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HSP90 chaperone cycle for steroid hormone receptors (SHR)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Cellular responses to external stimuli

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hsph1	ENSMUSG00000029657	0.0325051220296005	0.0975153660888015	1	1	1	1
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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Cellular responses to stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Hspa8	ENSMUSG00000015656	0.0230207752632622	0.0690623257897865	0.925444427431699	0.925444427431699	0.850721744111585	0.925444427431699
Hsph1	ENSMUSG00000029657	0.0325051220296005	0.0975153660888015	1	1	1	1
Hspa1b	ENSMUSG00000090877	0.514934023620344	0.6978446011211	0.635703516568382	0.6978446011211	0.6978446011211	0.6978446011211
Hspa1a	ENSMUSG00000091971	0.208897379073412	0.575536202757516	0.573498913947369	0.575536202757516	0.575536202757516	0.575536202757516

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orange

[1] “No significantly overrepresented pathways reported”

pink2

Apoptosis - multiple species

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bcl2l1	ENSMUSG00000007659	0.299349060054895	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152

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Osteoclast differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rac1	ENSMUSG00000001847	0.34837756124189	0.926441990075769	0.926441990075769	0.926441990075769	0.643359829732651	0.926441990075769
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Junb	ENSMUSG00000052837	0.398108175780842	0.852175490580835	0.710001140920767	0.852175490580835	0.852175490580835	0.852175490580835

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Toxoplasmosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bcl2l1	ENSMUSG00000007659	0.299349060054895	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Nfkbib	ENSMUSG00000030595	0.643359829732651	0.852832278580641	0.852832278580641	0.852832278580641	0.710208797518812	0.852832278580641

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Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Bcl2l1	ENSMUSG00000007659	0.299349060054895	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Zfp874b	ENSMUSG00000059839	0.120850531362929	0.362551594088788	0.853801250889739	0.853801250889739	0.78180291566155	0.853801250889739
Zfp120	ENSMUSG00000068134	0.149930038858385	0.449790116575155	0.848041159969572	0.848041159969572	0.505838378028518	0.758757567042777
Zfp874a	ENSMUSG00000069206	0.0763619660358786	0.229085898107636	0.454942951775341	0.454942951775341	0.454942951775341	0.454942951775341

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Human immunodeficiency virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rac1	ENSMUSG00000001847	0.34837756124189	0.926441990075769	0.926441990075769	0.926441990075769	0.643359829732651	0.926441990075769
Bcl2l1	ENSMUSG00000007659	0.299349060054895	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152
Pak4	ENSMUSG00000030602	0.34837756124189	1	0.926658283600152	1	1	1

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Lipid and atherosclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rac1	ENSMUSG00000001847	0.34837756124189	0.926441990075769	0.926441990075769	0.926441990075769	0.643359829732651	0.926441990075769
Bcl2l1	ENSMUSG00000007659	0.299349060054895	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Mib1	ENSMUSG00000024294	0.399548817627028	0.5155648232968	0.299349060054895	0.5155648232968	0.5155648232968	0.5155648232968
Tnfrsf1a	ENSMUSG00000030341	0.17924968721805	0.537749061654149	0.926658283600152	0.926658283600152	0.711854160331342	0.926658283600152

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red4

Fatty acid degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Echs1	ENSMUSG00000025465	0.209636747299872	0.506153679382925	0.926003599371282	0.926003599371282	0.337435786255283	0.506153679382925
Adh5	ENSMUSG00000028138	0.319786844594194	0.42013209553641	0.0932392199682756	0.279717659904827	0.42013209553641	0.42013209553641

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rosybrown3

B cell receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd79a	ENSMUSG00000003379	0.43283647035887	0.852832278580641	0.624685493301961	0.852832278580641	0.852832278580641	0.852832278580641
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Cr2	ENSMUSG00000026616	0.755951227598167	0.851954599472143	0.467427375670912	0.851954599472143	0.851954599472143	0.851954599472143
Fcgr2b	ENSMUSG00000026656	0.338976281569376	0.755733790684098	0.503822527122732	0.755733790684098	0.781170242226513	0.781170242226513
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Cd72	ENSMUSG00000028459	0.157372722062346	0.472118166187038	0.841947457210824	0.925217182211634	0.925217182211634	0.925217182211634
Lilra6	ENSMUSG00000030427	0.168646652367078	0.252969978550618	0.437393870295853	0.437393870295853	0.000333936947699979	0.00100181084309994
Cd22	ENSMUSG00000030577	0.416405862125981	1	0.758766047369853	1	1	1
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Cd79b	ENSMUSG00000040592	0.189061599254104	0.567184797762312	0.607438359373598	0.849805525376199	0.849805525376199	0.849805525376199
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887
Gm14548	ENSMUSG00000074417	0.686149754455511	0.686149754455511	0.247825081352574	0.371737622028861	0.00814448596985833	0.024433457909575
Gm15922	ENSMUSG00000081665	0.836417291431822	0.919553827300497	0.919553827300497	0.919553827300497	0.0108345665755802	0.0325036997267405
Pira2	ENSMUSG00000089942	0.553410011703054	0.553410011703054	0.388491809581663	0.553410011703054	0.511742979522636	0.553410011703054

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T cell receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Ctla4	ENSMUSG00000026011	0.200650219614881	0.450143880930327	1	1	0.300095920620218	0.450143880930327
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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NF-kappa B signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Tnfaip3	ENSMUSG00000019850	0.400265374208515	0.400265374208515	0.400265374208515	0.400265374208515	0.211110344399808	0.400265374208515
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Traf1	ENSMUSG00000026875	0.0103546374915853	0.0155319562373779	1	1	0.00236268169165983	0.0070880450749795
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Cyld	ENSMUSG00000036712	0.852940894477647	0.852940894477647	0.447265995733381	0.675667401277161	0.450444934184774	0.675667401277161
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Ccl19	ENSMUSG00000071005	0.266267359102332	0.366585264720911	0.366585264720911	0.366585264720911	0.207785104847071	0.366585264720911
Bcl2a1b	ENSMUSG00000089929	0.0315593554855452	0.0946780664566357	0.633039971999413	0.633039971999413	0.17924968721805	0.268874530827074
Ccl21a	ENSMUSG00000094686	0.146800541856249	0.440401625568746	1	1	0.853480389728993	1
Edaradd	ENSMUSG00000095105	0.85117361048289	0.85117361048289	0.449391287230099	0.674086930845148	0.346527959006435	0.674086930845148

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Leukocyte transendothelial migration

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Rassf5	ENSMUSG00000026430	0.105448082875634	0.178988771624031	0.923868938547269	0.923868938547269	0.119325847749354	0.178988771624031
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Rhoh	ENSMUSG00000029204	0.250984986203665	0.752954958610994	0.840166843916795	0.840166843916795	0.638824656785692	0.840166843916795
Mylpf	ENSMUSG00000030672	0.397384062266614	0.596076093399921	0.214037080764326	0.596076093399921	0.707899741868332	0.707899741868332
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Msn	ENSMUSG00000031207	0.283930443883615	0.342405296020882	0.342405296020882	0.342405296020882	0.245326864841171	0.342405296020882
Jam3	ENSMUSG00000031990	0.5155648232968	0.7733472349452	0.348008842235184	0.7733472349452	0.78180291566155	0.78180291566155
Thy1	ENSMUSG00000032011	0.246478961478169	0.739436884434508	0.92622377157404	0.92622377157404	0.78180291566155	0.92622377157404
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Txk	ENSMUSG00000054892	0.0897372356882883	0.269211707064865	0.852832278580641	0.852832278580641	0.399548817627028	0.599323226440542
Cldn23	ENSMUSG00000055976	0.454600801949285	0.781170242226513	0.780851835278818	0.781170242226513	0.781170242226513	0.781170242226513
Sipa1	ENSMUSG00000056917	0.250984986203665	0.597162263671263	1	1	0.398108175780842	0.597162263671263
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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Osteoclast differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Spi1	ENSMUSG00000002111	0.338976281569376	0.508464422354065	0.177853449259986	0.508464422354065	0.642366752097095	0.642366752097095
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Fcgr2b	ENSMUSG00000026656	0.338976281569376	0.755733790684098	0.503822527122732	0.755733790684098	0.781170242226513	0.781170242226513
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lilra6	ENSMUSG00000030427	0.168646652367078	0.252969978550618	0.437393870295853	0.437393870295853	0.000333936947699979	0.00100181084309994
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Cyld	ENSMUSG00000036712	0.852940894477647	0.852940894477647	0.447265995733381	0.675667401277161	0.450444934184774	0.675667401277161
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Camk4	ENSMUSG00000038128	0.680744598257505	0.680744598257505	0.178692663513448	0.380498235572952	0.253665490381968	0.380498235572952
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492
Gm14548	ENSMUSG00000074417	0.686149754455511	0.686149754455511	0.247825081352574	0.371737622028861	0.00814448596985833	0.024433457909575
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062
Gm15922	ENSMUSG00000081665	0.836417291431822	0.919553827300497	0.919553827300497	0.919553827300497	0.0108345665755802	0.0325036997267405
Pira2	ENSMUSG00000089942	0.553410011703054	0.553410011703054	0.388491809581663	0.553410011703054	0.511742979522636	0.553410011703054

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Primary immunodeficiency

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Aire	ENSMUSG00000000731	0.922635307646004	0.922635307646004	0.695706182905486	0.922635307646004	0.513346277289108	0.922635307646004
Cd79a	ENSMUSG00000003379	0.43283647035887	0.852832278580641	0.624685493301961	0.852832278580641	0.852832278580641	0.852832278580641
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Rfx5	ENSMUSG00000005774	0.851954599472143	0.851954599472143	0.851732715229127	0.851954599472143	0.297848640636702	0.851954599472143
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1

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Th1 and Th2 cell differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Tbx21	ENSMUSG00000001444	0.142165951159432	0.213248926739148	0.119631084167592	0.213248926739148	0.454942951775341	0.454942951775341
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Notch2	ENSMUSG00000027878	0.560950328333967	0.710416009055326	0.63250023504486	0.710416009055326	0.710416009055326	0.710416009055326
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Stat4	ENSMUSG00000062939	0.920461794456068	0.920461794456068	0.764115430291227	0.920461794456068	0.157741398767132	0.473224196301396
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Runx3	ENSMUSG00000070691	0.497625221907634	0.924987846321933	0.633039971999413	0.924987846321933	0.924987846321933	0.924987846321933

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Th17 cell differentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Tbx21	ENSMUSG00000001444	0.142165951159432	0.213248926739148	0.119631084167592	0.213248926739148	0.454942951775341	0.454942951775341
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Il27ra	ENSMUSG00000005465	0.108244222162358	0.324732666487074	1	1	0.455625354715449	0.683438032073173
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Irf4	ENSMUSG00000021356	0.12935516793705	0.12935516793705	0.0880615565264046	0.12935516793705	0.0226344734406829	0.0679034203220487
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Rara	ENSMUSG00000037992	0.179249687218049	0.537749061654148	0.92622377157404	0.92622377157404	0.78148726569172	0.92622377157404
Foxp3	ENSMUSG00000039521	0.752117204139398	0.752117204139398	0.377618925251014	0.752117204139398	0.669349543523297	0.752117204139398
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133

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Chemokine signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Dock2	ENSMUSG00000020143	0.27871391172685	0.675141569480709	0.692783110017144	0.692783110017144	0.450094379653806	0.675141569480709
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Cxcl13	ENSMUSG00000023078	0.607438359373598	0.607438359373598	0.0963817845133188	0.289145353539956	0.505838378028518	0.607438359373598
Adrbk1	ENSMUSG00000024858	0.0162664168407233	0.0333757576418323	0.0701431284016184	0.0701431284016184	0.0222505050945549	0.0333757576418323
Ccr1	ENSMUSG00000025804	0.254414773803597	0.340887582990546	0.340887582990546	0.340887582990546	0.00289311433957183	0.0086793430187155
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Was	ENSMUSG00000031165	0.437018196691686	0.703999362653679	0.700398062529209	0.703999362653679	0.703999362653679	0.703999362653679
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Ccl22	ENSMUSG00000031779	0.0115535350288052	0.0346606050864156	0.453225835454266	0.513665062682276	0.513665062682276	0.513665062682276
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Ccr7	ENSMUSG00000037944	0.348695725789392	0.406993622340116	0.406993622340116	0.406993622340116	0.0947558980989551	0.284267694296865
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Prex1	ENSMUSG00000039621	0.0566379395854604	0.0849569093781906	0.636229315311352	0.636229315311352	0.0421101560083839	0.0849569093781906
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Elmo1	ENSMUSG00000041112	0.179945789077372	0.51755608657933	0.926550375688041	0.926550375688041	0.345037391052887	0.51755608657933
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Cxcr5	ENSMUSG00000047880	0.679629711532125	0.83686344227219	0.83686344227219	0.83686344227219	0.689008130685424	0.83686344227219
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Arrb2	ENSMUSG00000060216	1	1	0.5155648232968	0.7733472349452	0.17750354896016	0.53251064688048
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Ccl19	ENSMUSG00000071005	0.266267359102332	0.366585264720911	0.366585264720911	0.366585264720911	0.207785104847071	0.366585264720911
Grk6	ENSMUSG00000074886	0.0113089139751576	0.0169633709627363	0.92380865295296	0.92380865295296	0.0101222094973346	0.0169633709627363
Ccl21a	ENSMUSG00000094686	0.146800541856249	0.440401625568746	1	1	0.853480389728993	1

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Intestinal immune network for IgA production

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Icosl	ENSMUSG00000000732	1	1	0.922317414627388	1	0.0743693776059063	0.223108132817719
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Hematopoietic cell lineage

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Fcer2a	ENSMUSG00000005540	0.676790649123307	0.851061028660105	0.68129770017266	0.851061028660105	0.851061028660105	0.851061028660105
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Cd5	ENSMUSG00000024669	0.0476022526559757	0.142806757967927	0.758766047369853	0.758766047369853	0.511097249598474	0.758766047369853
Ms4a1	ENSMUSG00000024673	0.469500032898643	0.606113826568149	0.606113826568149	0.606113826568149	0.513665062682276	0.606113826568149
Cr2	ENSMUSG00000026616	0.755951227598167	0.851954599472143	0.467427375670912	0.851954599472143	0.851954599472143	0.851954599472143
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Cd2	ENSMUSG00000027863	1	1	0.222938437045269	0.668815311135807	0.701310685803632	1
Cd1d1	ENSMUSG00000028076	0.0315593554855452	0.0946780664566356	0.852504981253341	0.853372965654504	0.853372965654504	0.853372965654504
Cd22	ENSMUSG00000030577	0.416405862125981	1	0.758766047369853	1	1	1
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Cd37	ENSMUSG00000030798	0.361925120061097	0.782117202022501	0.607438359373598	0.782117202022501	0.782117202022501	0.782117202022501
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Csf2ra	ENSMUSG00000059326	0.577829325134931	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Il3ra	ENSMUSG00000068758	0.00749632974009822	0.0224889892202947	0.643112334413352	0.643112334413352	0.1168786685029	0.17531800275435

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PD-L1 expression and PD-1 checkpoint pathway in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991

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Natural killer cell mediated cytotoxicity

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Cd48	ENSMUSG00000015355	0.118409250205154	0.355227750615461	0.773651283337324	0.773651283337324	0.292141300005423	0.438211950008134
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
Klrb1c	ENSMUSG00000030325	0.514934023620345	0.7802108304765	0.57466664340579	0.7802108304765	0.7802108304765	0.7802108304765
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Ulbp1	ENSMUSG00000079685	0.782117202022501	0.782117202022501	0.5155648232968	0.7733472349452	0.0936419271039908	0.280925781311972

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Cell adhesion molecules

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Icosl	ENSMUSG00000000732	1	1	0.922317414627388	1	0.0743693776059063	0.223108132817719
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Cd6	ENSMUSG00000024670	0.123175587755902	0.369526763267706	0.842349984490669	0.847921313356738	0.847921313356738	0.847921313356738
Itgb8	ENSMUSG00000025321	0.686937109830067	1	0.412182162844325	1	1	1
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Ctla4	ENSMUSG00000026011	0.200650219614881	0.450143880930327	1	1	0.300095920620218	0.450143880930327
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Sell	ENSMUSG00000026581	0.605780600170041	0.627251366276275	0.469087410349614	0.627251366276275	0.627251366276275	0.627251366276275
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Cd2	ENSMUSG00000027863	1	1	0.222938437045269	0.668815311135807	0.701310685803632	1
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Cd22	ENSMUSG00000030577	0.416405862125981	1	0.758766047369853	1	1	1
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Jam3	ENSMUSG00000031990	0.5155648232968	0.7733472349452	0.348008842235184	0.7733472349452	0.78180291566155	0.78180291566155
Ntng2	ENSMUSG00000035513	0.058823267388015	0.176469802164045	0.643359829732651	0.781170242226513	0.781170242226513	0.781170242226513
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Spn	ENSMUSG00000051457	0.109793509122179	0.31112022882692	0.710416009055326	0.710416009055326	0.207413485884614	0.31112022882692
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Cldn23	ENSMUSG00000055976	0.454600801949285	0.781170242226513	0.780851835278818	0.781170242226513	0.781170242226513	0.781170242226513
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Leishmaniasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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Epstein-Barr virus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Fcer2a	ENSMUSG00000005540	0.676790649123307	0.851061028660105	0.68129770017266	0.851061028660105	0.851061028660105	0.851061028660105
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Tnfaip3	ENSMUSG00000019850	0.400265374208515	0.400265374208515	0.400265374208515	0.400265374208515	0.211110344399808	0.400265374208515
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Cr2	ENSMUSG00000026616	0.755951227598167	0.851954599472143	0.467427375670912	0.851954599472143	0.851954599472143	0.851954599472143
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Oas1b	ENSMUSG00000029605	0.0756145297453648	0.113421794618047	0.638824656785692	0.638824656785692	0.024062085667391	0.072186257002173
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Runx3	ENSMUSG00000070691	0.497625221907634	0.924987846321933	0.633039971999413	0.924987846321933	0.924987846321933	0.924987846321933
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

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Cytokine-cytokine receptor interaction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il16	ENSMUSG00000001741	0.270898788519615	0.6275332346787	0.6275332346787	0.6275332346787	0.573791743469336	0.6275332346787
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Il17ra	ENSMUSG00000002897	0.17750354896016	0.53251064688048	0.390375870115423	0.585563805173135	0.852065168704833	0.852065168704833
Ebi3	ENSMUSG00000003206	0.147458757705094	0.221188136557642	0.00768144932639892	0.0230443479791968	0.85117361048289	0.85117361048289
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Il27ra	ENSMUSG00000005465	0.108244222162358	0.324732666487074	1	1	0.455625354715449	0.683438032073173
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Relt	ENSMUSG00000008318	0.703333998861023	0.703333998861023	0.624685493301961	0.703333998861023	0.0432318933800774	0.129695680140232
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
Cxcl13	ENSMUSG00000023078	0.607438359373598	0.607438359373598	0.0963817845133188	0.289145353539956	0.505838378028518	0.607438359373598
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Gdf11	ENSMUSG00000025352	0.686937109830067	0.686937109830067	0.533305492606139	0.686937109830067	0.68129770017266	0.686937109830067
Ccr1	ENSMUSG00000025804	0.254414773803597	0.340887582990546	0.340887582990546	0.340887582990546	0.00289311433957183	0.0086793430187155
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Tnfsf8	ENSMUSG00000028362	0.307838294631065	0.354081512249118	0.354081512249118	0.354081512249118	0.264135602004534	0.354081512249118
Cntfr	ENSMUSG00000028444	0.776750778128093	0.776750778128093	0.776750778128093	0.776750778128093	0.450444934184774	0.776750778128093
Tnfrsf8	ENSMUSG00000028602	0.253668577981715	0.253668577981715	0.176451829330851	0.253668577981715	0.00468160475316412	0.0140448142594924
Tnfrsf9	ENSMUSG00000028965	0.329576740674783	0.504410496659194	0.843929879174112	0.843929879174112	0.336273664439462	0.504410496659194
Tnfrsf4	ENSMUSG00000029075	0.454600801949285	0.782117202022501	0.711854160331342	0.782117202022501	0.782117202022501	0.782117202022501
Cd27	ENSMUSG00000030336	0.328374849423202	0.642864324224729	0.615734841980377	0.642864324224729	0.642864324224729	0.642864324224729
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Ccl22	ENSMUSG00000031779	0.0115535350288052	0.0346606050864156	0.453225835454266	0.513665062682276	0.513665062682276	0.513665062682276
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Ccr7	ENSMUSG00000037944	0.348695725789392	0.406993622340116	0.406993622340116	0.406993622340116	0.0947558980989551	0.284267694296865
Clcf1	ENSMUSG00000040663	0.769866760519794	0.769866760519794	0.566285712787375	0.769866760519794	0.300095920620218	0.769866760519794
Tnfrsf18	ENSMUSG00000041954	0.109793509122179	0.329380527366537	0.776919261684345	0.776919261684345	0.5155648232968	0.7733472349452
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Cxcr5	ENSMUSG00000047880	0.679629711532125	0.83686344227219	0.83686344227219	0.83686344227219	0.689008130685424	0.83686344227219
Osm	ENSMUSG00000058755	0.210374401237615	0.210374401237615	0.0164739112492867	0.0247108668739301	0.0160600007544847	0.0247108668739301
Csf2ra	ENSMUSG00000059326	0.577829325134931	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Il3ra	ENSMUSG00000068758	0.00749632974009822	0.0224889892202947	0.643112334413352	0.643112334413352	0.1168786685029	0.17531800275435
Ccl19	ENSMUSG00000071005	0.266267359102332	0.366585264720911	0.366585264720911	0.366585264720911	0.207785104847071	0.366585264720911
Ccl21a	ENSMUSG00000094686	0.146800541856249	0.440401625568746	1	1	0.853480389728993	1

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Human immunodeficiency virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Ap1m1	ENSMUSG00000003033	1	1	1	1	0.0753654386865989	0.226096316059797
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Apobec3	ENSMUSG00000009585	0.0741204440774083	0.175777610154895	0.502464977245519	0.502464977245519	0.117185073436597	0.175777610154895
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Ap1s2	ENSMUSG00000031367	0.853049270252403	0.853049270252403	0.177853449259986	0.533560347779959	0.643853282854191	0.853049270252403
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Mb21d1	ENSMUSG00000032344	0.577259514257969	0.577259514257969	0.507168839166081	0.577259514257969	0.299349060054895	0.577259514257969
Atr	ENSMUSG00000032409	0.45596561163947	0.5155648232968	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Ap1s3	ENSMUSG00000054702	0.400265374208515	0.769540304784424	1	1	0.513026869856283	0.769540304784424
Trim12c	ENSMUSG00000057143	0.501782052576058	0.705968934865368	0.0402554607499039	0.120766382249712	0.705968934865368	0.705968934865368
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Trim5	ENSMUSG00000060441	0.398108175780842	0.454942951775342	0.242231702094921	0.454942951775342	0.454942951775342	0.454942951775342
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

Download data as csv

Platelet activation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Fermt3	ENSMUSG00000024965	0.130037529335642	0.390112588006927	0.494796118234289	0.494796118234289	0.390750658104794	0.494796118234289
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Tbxa2r	ENSMUSG00000034881	0.0426702157436794	0.128010647231038	0.211844580334808	0.317766870502212	0.514934023620344	0.514934023620344
P2ry12	ENSMUSG00000036353	0.449743164679353	0.67461474701903	0.853372965654504	0.853372965654504	0.0219958379984644	0.0659875139953931
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Ptgs1	ENSMUSG00000047250	0.290210015182478	0.435315022773717	0.177153312234059	0.435315022773717	1	1
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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Yersinia infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Arpc5l	ENSMUSG00000026755	1	1	0.255530331334266	0.766590994002797	0.853372965654504	1
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Was	ENSMUSG00000031165	0.437018196691686	0.703999362653679	0.700398062529209	0.703999362653679	0.703999362653679	0.703999362653679
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Elmo1	ENSMUSG00000041112	0.179945789077372	0.51755608657933	0.926550375688041	0.926550375688041	0.345037391052887	0.51755608657933
Git2	ENSMUSG00000041890	0.92622377157404	0.92622377157404	0.395928178642446	0.92622377157404	0.709375484777034	0.92622377157404
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Wipf1	ENSMUSG00000075284	0.55205880554923	0.55205880554923	0.505169133438821	0.55205880554923	0.371967876858695	0.55205880554923

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Human T-cell leukemia virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Spi1	ENSMUSG00000002111	0.338976281569376	0.508464422354065	0.177853449259986	0.508464422354065	0.642366752097095	0.642366752097095
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Elk4	ENSMUSG00000026436	0.0743693776059064	0.223108132817719	0.848280005680805	0.848280005680805	0.846460676830692	0.848280005680805
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Ets1	ENSMUSG00000032035	0.0869438727002335	0.2608316181007	0.921139684946258	0.921139684946258	0.334323804341914	0.501485706512871
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Atr	ENSMUSG00000032409	0.45596561163947	0.5155648232968	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Egr2	ENSMUSG00000037868	0.923321156062851	0.923321156062851	0.84992097596507	0.923321156062851	0.15994648990251	0.47983946970753
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

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Rap1 signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Efna2	ENSMUSG00000003070	0.781645261743309	0.781645261743309	0.45253450475104	0.781645261743309	0.780692109850228	0.781645261743309
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Adora2a	ENSMUSG00000020178	0.639337105615665	0.639337105615665	0.290210015182478	0.516994836448955	0.344663224299303	0.516994836448955
Evl	ENSMUSG00000021262	0.769496350735448	0.769496350735448	0.291756209988535	0.769496350735448	0.567513221841557	0.769496350735448
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Rassf5	ENSMUSG00000026430	0.105448082875634	0.178988771624031	0.923868938547269	0.923868938547269	0.119325847749354	0.178988771624031
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Lpar2	ENSMUSG00000031861	0.513026869856283	0.513026869856283	0.297095062262363	0.445642593393545	0.0741204440774084	0.222361332232225
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Prkd2	ENSMUSG00000041187	0.633039971999413	0.926003599371282	0.700627001620904	0.926003599371282	0.926003599371282	0.926003599371282
Id1	ENSMUSG00000042745	0.926658283600152	0.926658283600152	0.712057867818062	0.926658283600152	0.400265374208515	0.926658283600152
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Rgs14	ENSMUSG00000052087	0.305641867748933	0.305641867748933	0.105136836521283	0.244301947115094	0.162867964743396	0.244301947115094
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Sipa1	ENSMUSG00000056917	0.250984986203665	0.597162263671263	1	1	0.398108175780842	0.597162263671263
Skap1	ENSMUSG00000057058	0.342405296020881	0.702439833942814	0.576973746230334	0.702439833942814	0.702439833942814	0.702439833942814
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887

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Chagas disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Ppp2r2c	ENSMUSG00000029120	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.34837756124189	0.853372965654504
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Gna15	ENSMUSG00000034792	0.78180291566155	1	1	1	0.347639524025037	1
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Kng2	ENSMUSG00000060459	0.92550091578426	0.92550091578426	0.568730419752528	0.92550091578426	0.63908115343663	0.92550091578426

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C-type lectin receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lsp1	ENSMUSG00000018819	0.277495194111025	0.638824656785692	0.638824656785692	0.638824656785692	0.505838378028518	0.638824656785692
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Clec4d	ENSMUSG00000030144	0.444032220827359	0.666048331241038	0.775389027507362	0.775389027507362	0.246095446958788	0.666048331241038
Ccl22	ENSMUSG00000031779	0.0115535350288052	0.0346606050864156	0.453225835454266	0.513665062682276	0.513665062682276	0.513665062682276
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Egr3	ENSMUSG00000033730	0.595734710730475	0.595734710730475	0.533305492606139	0.595734710730475	0.334647501634712	0.595734710730475
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Cyld	ENSMUSG00000036712	0.852940894477647	0.852940894477647	0.447265995733381	0.675667401277161	0.450444934184774	0.675667401277161
Egr2	ENSMUSG00000037868	0.923321156062851	0.923321156062851	0.84992097596507	0.923321156062851	0.15994648990251	0.47983946970753
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1

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Lipid and atherosclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pou2f2	ENSMUSG00000008496	0.598933903427089	0.598933903427089	0.458890710010385	0.598933903427089	0.425792187518042	0.598933903427089
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ager	ENSMUSG00000015452	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.400265374208515	0.600398061312773
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Abcg1	ENSMUSG00000024030	0.115651627788147	0.346954883364442	0.568730419752528	0.780692109850228	0.780692109850228	0.780692109850228
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Vldlr	ENSMUSG00000024924	0.285514721052844	0.756745783696498	0.92622377157404	0.92622377157404	0.504497189130999	0.756745783696498
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Cyp1a1	ENSMUSG00000032315	0.776750778128093	0.776750778128093	0.087782173751782	0.263346521255346	0.711650020253571	0.776750778128093
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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MAPK signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Efna2	ENSMUSG00000003070	0.781645261743309	0.781645261743309	0.45253450475104	0.781645261743309	0.780692109850228	0.781645261743309
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Mef2c	ENSMUSG00000005583	0.749775747200219	0.752577660361457	0.679629711532125	0.752577660361457	0.752577660361457	0.752577660361457
Cacna1d	ENSMUSG00000015968	0.642864324224729	0.711650020253571	0.711650020253571	0.711650020253571	0.399548817627028	0.711650020253571
Stk4	ENSMUSG00000018209	0.781170242226513	0.78180291566155	0.78180291566155	0.78180291566155	0.207413485884613	0.62224045765384
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Cacna1i	ENSMUSG00000022416	0.829928232630808	0.831255031223636	0.829928232630808	0.831255031223636	0.831255031223636	0.831255031223636
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Map4k2	ENSMUSG00000024948	0.338592117141989	0.507888175712984	1	1	0.120850531362929	0.362551594088788
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Map4k4	ENSMUSG00000026074	0.5155648232968	0.7733472349452	0.514934023620345	0.7733472349452	0.926550375688041	0.926550375688041
Elk4	ENSMUSG00000026436	0.0743693776059064	0.223108132817719	0.848280005680805	0.848280005680805	0.846460676830692	0.848280005680805
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Dusp2	ENSMUSG00000027368	0.535966800473837	0.681847941017729	0.681847941017729	0.681847941017729	0.57113445032749	0.681847941017729
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Rasgrp4	ENSMUSG00000030589	0.5155648232968	0.5155648232968	0.148772260628989	0.223158390943484	0.119631084167592	0.223158390943484
Ptpn7	ENSMUSG00000031506	0.0387859097571856	0.116357729271557	0.565047747060087	0.565047747060087	0.0969812105731562	0.145471815859734
Dusp4	ENSMUSG00000031530	0.781011212316137	0.781011212316137	0.576687400573867	0.781011212316137	0.145811394942709	0.437434184828127
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Map4k1	ENSMUSG00000037337	0.201008592962987	0.603025778888962	0.68129770017266	0.841812594759375	0.841812594759375	0.841812594759375
Cacna2d4	ENSMUSG00000041460	0.332776743239854	0.334617324970328	0.334617324970328	0.334617324970328	0.332776743239854	0.334617324970328
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Dusp7	ENSMUSG00000053716	0.45596561163947	0.683948417459205	1	1	0.298974794311434	0.683948417459205
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Arrb2	ENSMUSG00000060216	1	1	0.5155648232968	0.7733472349452	0.17750354896016	0.53251064688048
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887

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Inflammatory bowel disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tbx21	ENSMUSG00000001444	0.142165951159432	0.213248926739148	0.119631084167592	0.213248926739148	0.454942951775341	0.454942951775341
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Foxp3	ENSMUSG00000039521	0.752117204139398	0.752117204139398	0.377618925251014	0.752117204139398	0.669349543523297	0.752117204139398
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Stat4	ENSMUSG00000062939	0.920461794456068	0.920461794456068	0.764115430291227	0.920461794456068	0.157741398767132	0.473224196301396
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133

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Malaria

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrb1f	ENSMUSG00000030154	0.0855462683080095	0.221681250014749	0.92212478749186	0.92212478749186	0.147787500009832	0.221681250014749
Klrb1c	ENSMUSG00000030325	0.514934023620345	0.7802108304765	0.57466664340579	0.7802108304765	0.7802108304765	0.7802108304765
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Klrb1b	ENSMUSG00000079298	0.0226344734406829	0.0679034203220487	0.55205880554923	0.55205880554923	0.0588232673880149	0.0882349010820223
Gypc	ENSMUSG00000090523	0.0073134885581712	0.0219404656745136	0.853480389728993	0.853480389728993	0.852940894477647	0.853480389728993

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Toll-like receptor signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Irf5	ENSMUSG00000029771	0.365324073403582	0.751644504901775	0.501096336601183	0.751644504901775	0.772767153280156	0.772767153280156
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Tlr7	ENSMUSG00000044583	0.705752031336119	0.781011212316137	0.706401308111632	0.781011212316137	0.781011212316137	0.781011212316137
Tlr1	ENSMUSG00000044827	0.17610058307789	0.264150874616835	0.0331400397096515	0.0994201191289544	0.781170242226513	0.781170242226513
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Fc epsilon RI signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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Tuberculosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Rfx5	ENSMUSG00000005774	0.851954599472143	0.851954599472143	0.851732715229127	0.851954599472143	0.297848640636702	0.851954599472143
Lsp1	ENSMUSG00000018819	0.277495194111025	0.638824656785692	0.638824656785692	0.638824656785692	0.505838378028518	0.638824656785692
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Fcgr2b	ENSMUSG00000026656	0.338976281569376	0.755733790684098	0.503822527122732	0.755733790684098	0.781170242226513	0.781170242226513
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Atp6v0d2	ENSMUSG00000028238	0.753035561236083	0.754842077504805	0.754842077504805	0.754842077504805	0.133883564214237	0.401650692642711
Coro1a	ENSMUSG00000030707	0.038420593013914	0.115261779041742	0.563485358844814	0.563485358844814	0.250285839267991	0.375428758901986
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Tlr1	ENSMUSG00000044827	0.17610058307789	0.264150874616835	0.0331400397096515	0.0994201191289544	0.781170242226513	0.781170242226513
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133

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Pathways in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tcf7	ENSMUSG00000000782	1	1	0.61878896230102	0.928183443451529	0.553410011703054	0.928183443451529
Spi1	ENSMUSG00000002111	0.338976281569376	0.508464422354065	0.177853449259986	0.508464422354065	0.642366752097095	0.642366752097095
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Wnt11	ENSMUSG00000015957	1	1	0.852175490580835	1	0.044737329683373	0.134211989050119
Stk4	ENSMUSG00000018209	0.781170242226513	0.78180291566155	0.78180291566155	0.78180291566155	0.207413485884613	0.62224045765384
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Dvl2	ENSMUSG00000020888	0.093084640707941	0.279253922123823	0.643853282854191	0.643853282854191	0.643359829732651	0.643853282854191
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Pmaip1	ENSMUSG00000024521	0.78180291566155	0.78180291566155	0.213307944885796	0.639923834657388	0.711240436189781	0.78180291566155
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Sufu	ENSMUSG00000025231	0.706831781264721	0.706831781264721	0.295581119060361	0.443371678590541	0.27173234335943	0.443371678590541
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Wnt10a	ENSMUSG00000026167	0.565283772038808	0.847925658058212	0.565283772038808	0.847925658058212	1	1
Rassf5	ENSMUSG00000026430	0.105448082875634	0.178988771624031	0.923868938547269	0.923868938547269	0.119325847749354	0.178988771624031
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Traf1	ENSMUSG00000026875	0.0103546374915853	0.0155319562373779	1	1	0.00236268169165983	0.0070880450749795
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Notch2	ENSMUSG00000027878	0.560950328333967	0.710416009055326	0.63250023504486	0.710416009055326	0.710416009055326	0.710416009055326
Lef1	ENSMUSG00000027985	0.659704394429487	0.659704394429487	0.658353668475243	0.659704394429487	0.24361318058863	0.659704394429487
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Wnt7a	ENSMUSG00000030093	0.275387266314552	0.275387266314552	0.275387266314552	0.275387266314552	0.275387266314551	0.275387266314552
Rasgrp4	ENSMUSG00000030589	0.5155648232968	0.5155648232968	0.148772260628989	0.223158390943484	0.119631084167592	0.223158390943484
Pim2	ENSMUSG00000031155	0.0763619660358786	0.229085898107636	0.45596561163947	0.45596561163947	0.254787123615605	0.382180685423408
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Lpar2	ENSMUSG00000031861	0.513026869856283	0.513026869856283	0.297095062262363	0.445642593393545	0.0741204440774084	0.222361332232225
Ets1	ENSMUSG00000032035	0.0869438727002335	0.2608316181007	0.921139684946258	0.921139684946258	0.334323804341914	0.501485706512871
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Rara	ENSMUSG00000037992	0.179249687218049	0.537749061654148	0.92622377157404	0.92622377157404	0.78148726569172	0.92622377157404
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Foxo1	ENSMUSG00000044167	0.769866760519794	0.846460676830692	0.297848640636702	0.846460676830692	0.846460676830692	0.846460676830692
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Csf2ra	ENSMUSG00000059326	0.577829325134931	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Kng2	ENSMUSG00000060459	0.92550091578426	0.92550091578426	0.568730419752528	0.92550091578426	0.63908115343663	0.92550091578426
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Stat4	ENSMUSG00000062939	0.920461794456068	0.920461794456068	0.764115430291227	0.920461794456068	0.157741398767132	0.473224196301396
Il3ra	ENSMUSG00000068758	0.00749632974009822	0.0224889892202947	0.643112334413352	0.643112334413352	0.1168786685029	0.17531800275435
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887

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Type I diabetes mellitus

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Ica1	ENSMUSG00000062995	0.514934023620345	0.710416009055326	0.710416009055326	0.710416009055326	0.514934023620345	0.710416009055326
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Allograft rejection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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AGE-RAGE signaling pathway in diabetic complications

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ager	ENSMUSG00000015452	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.400265374208515	0.600398061312773
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Foxo1	ENSMUSG00000044167	0.769866760519794	0.846460676830692	0.297848640636702	0.846460676830692	0.846460676830692	0.846460676830692
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296

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Fc gamma R-mediated phagocytosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Bin1	ENSMUSG00000024381	0.766080166042519	0.926003599371282	0.201408665602973	0.604225996808919	0.926003599371282	0.926003599371282
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Fcgr2b	ENSMUSG00000026656	0.338976281569376	0.755733790684098	0.503822527122732	0.755733790684098	0.781170242226513	0.781170242226513
Arpc5l	ENSMUSG00000026755	1	1	0.255530331334266	0.766590994002797	0.853372965654504	1
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Was	ENSMUSG00000031165	0.437018196691686	0.703999362653679	0.700398062529209	0.703999362653679	0.703999362653679	0.703999362653679
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219

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Human cytomegalovirus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Ccr1	ENSMUSG00000025804	0.254414773803597	0.340887582990546	0.340887582990546	0.340887582990546	0.00289311433957183	0.0086793430187155
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Eif4ebp1	ENSMUSG00000031490	0.342405296020881	0.450444934184774	0.450444934184774	0.450444934184774	0.146800541856249	0.440401625568746
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Mb21d1	ENSMUSG00000032344	0.577259514257969	0.577259514257969	0.507168839166081	0.577259514257969	0.299349060054895	0.577259514257969
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

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Sphingolipid signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Nsmaf	ENSMUSG00000028245	0.146800541856249	0.440401625568746	0.452880492349546	0.514934023620345	0.514934023620345	0.514934023620345
Ppp2r2c	ENSMUSG00000029120	0.643359829732651	0.853372965654504	0.853372965654504	0.853372965654504	0.34837756124189	0.853372965654504
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
S1pr2	ENSMUSG00000043895	0.0241933715424143	0.0725801146272429	0.852504981253341	0.852504981253341	0.513026869856283	0.769540304784424
S1pr4	ENSMUSG00000044199	0.178287767933578	0.534863303800733	0.424592967853335	0.636889451780002	0.781011212316137	0.781011212316137
S1pr1	ENSMUSG00000045092	0.628654363853655	0.628654363853655	0.384672302267076	0.577008453400614	0.293293089483362	0.577008453400614
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Kng2	ENSMUSG00000060459	0.92550091578426	0.92550091578426	0.568730419752528	0.92550091578426	0.63908115343663	0.92550091578426
S1pr3	ENSMUSG00000067586	0.00731348855817121	0.0219404656745136	0.392243127063687	0.505169133438821	0.505169133438821	0.505169133438821

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Inositol phosphate metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Inpp5k	ENSMUSG00000006127	0.643853282854191	0.7802108304765	0.511742979522636	0.7802108304765	0.7802108304765	0.7802108304765
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Pip4k2b	ENSMUSG00000018547	0.393724994268831	0.590587491403246	0.642366752097095	0.642366752097095	0.246861959455465	0.590587491403246
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Pip4k2a	ENSMUSG00000026737	0.283930443883615	0.751644504901775	0.501096336601183	0.751644504901775	1	1
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Inpp4b	ENSMUSG00000037940	0.633039971999413	0.633039971999413	0.141500034183268	0.222173997210624	0.148115998140416	0.222173997210624
Itpkb	ENSMUSG00000038855	0.348008842235184	0.767614469283954	0.511742979522636	0.767614469283954	0.852504981253341	0.852504981253341
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Inpp5f	ENSMUSG00000042105	0.400265374208515	0.600398061312773	0.925444427431699	0.925444427431699	0.343537039781257	0.600398061312773

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Graft-versus-host disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Viral protein interaction with cytokine and cytokine receptor

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Cxcl13	ENSMUSG00000023078	0.607438359373598	0.607438359373598	0.0963817845133188	0.289145353539956	0.505838378028518	0.607438359373598
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Ccr1	ENSMUSG00000025804	0.254414773803597	0.340887582990546	0.340887582990546	0.340887582990546	0.00289311433957183	0.0086793430187155
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Ccl22	ENSMUSG00000031779	0.0115535350288052	0.0346606050864156	0.453225835454266	0.513665062682276	0.513665062682276	0.513665062682276
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Ccr7	ENSMUSG00000037944	0.348695725789392	0.406993622340116	0.406993622340116	0.406993622340116	0.0947558980989551	0.284267694296865
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Cxcr5	ENSMUSG00000047880	0.679629711532125	0.83686344227219	0.83686344227219	0.83686344227219	0.689008130685424	0.83686344227219
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
Ccl19	ENSMUSG00000071005	0.266267359102332	0.366585264720911	0.366585264720911	0.366585264720911	0.207785104847071	0.366585264720911
Ccl21a	ENSMUSG00000094686	0.146800541856249	0.440401625568746	1	1	0.853480389728993	1

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Neurotrophin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sh2b2	ENSMUSG00000005057	0.49228148038523	0.770019415933663	0.92350506192425	0.92350506192425	0.513346277289108	0.770019415933663
Psen2	ENSMUSG00000010609	0.325546457901448	0.493164240322614	0.328776160215076	0.493164240322614	0.768937368234818	0.768937368234818
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Irak3	ENSMUSG00000020227	0.926003599371282	0.926003599371282	0.78180291566155	0.926003599371282	0.246478961478169	0.739436884434508
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Arhgdib	ENSMUSG00000030220	0.0796737817624351	0.239021345287305	0.764907246611494	0.764907246611494	0.505169133438821	0.757753700158231
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Camk4	ENSMUSG00000038128	0.680744598257505	0.680744598257505	0.178692663513448	0.380498235572952	0.253665490381968	0.380498235572952
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Ntrk3	ENSMUSG00000059146	0.51398322803049	0.770974842045735	0.14712977154559	0.441389314636769	0.781645261743309	0.781645261743309
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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Cellular senescence

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Cacna1d	ENSMUSG00000015968	0.642864324224729	0.711650020253571	0.711650020253571	0.711650020253571	0.399548817627028	0.711650020253571
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Zfp36l1	ENSMUSG00000021127	0.254787123615605	0.764361370846816	0.853480389728993	0.853480389728993	0.849457568495547	0.853480389728993
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Rad9a	ENSMUSG00000024824	0.0441715176243983	0.132514552873195	0.924872384323463	0.924872384323463	0.0969812105731562	0.145471815859734
Rassf5	ENSMUSG00000026430	0.105448082875634	0.178988771624031	0.923868938547269	0.923868938547269	0.119325847749354	0.178988771624031
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Eif4ebp1	ENSMUSG00000031490	0.342405296020881	0.450444934184774	0.450444934184774	0.450444934184774	0.146800541856249	0.440401625568746
Ets1	ENSMUSG00000032035	0.0869438727002335	0.2608316181007	0.921139684946258	0.921139684946258	0.334323804341914	0.501485706512871
Atr	ENSMUSG00000032409	0.45596561163947	0.5155648232968	0.5155648232968	0.5155648232968	0.398108175780842	0.5155648232968
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Foxo1	ENSMUSG00000044167	0.769866760519794	0.846460676830692	0.297848640636702	0.846460676830692	0.846460676830692	0.846460676830692
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

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VEGF signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Sh2d2a	ENSMUSG00000028071	0.0886202385494146	0.132930357824122	0.486765503970733	0.486765503970733	0.0535981760208404	0.132930357824122
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1

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Measles

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Slamf1	ENSMUSG00000015316	0.16467231040779	0.2590761028229	0.667172356041102	0.667172356041102	0.172717401881933	0.2590761028229
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Tnfaip3	ENSMUSG00000019850	0.400265374208515	0.400265374208515	0.400265374208515	0.400265374208515	0.211110344399808	0.400265374208515
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Fcgr2b	ENSMUSG00000026656	0.338976281569376	0.755733790684098	0.503822527122732	0.755733790684098	0.781170242226513	0.781170242226513
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Oas1b	ENSMUSG00000029605	0.0756145297453648	0.113421794618047	0.638824656785692	0.638824656785692	0.024062085667391	0.072186257002173
Msn	ENSMUSG00000031207	0.283930443883615	0.342405296020882	0.342405296020882	0.342405296020882	0.245326864841171	0.342405296020882
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Tlr7	ENSMUSG00000044583	0.705752031336119	0.781011212316137	0.706401308111632	0.781011212316137	0.781011212316137	0.781011212316137
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296

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Ras signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Efna2	ENSMUSG00000003070	0.781645261743309	0.781645261743309	0.45253450475104	0.781645261743309	0.780692109850228	0.781645261743309
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Stk4	ENSMUSG00000018209	0.781170242226513	0.78180291566155	0.78180291566155	0.78180291566155	0.207413485884613	0.62224045765384
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Htr7	ENSMUSG00000024798	0.119020462826154	0.357061388478463	0.706401308111632	0.706401308111632	0.245711415034162	0.368567122551243
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Rassf5	ENSMUSG00000026430	0.105448082875634	0.178988771624031	0.923868938547269	0.923868938547269	0.119325847749354	0.178988771624031
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Pla2g2f	ENSMUSG00000028749	0.255530331334266	0.766590994002797	0.703333998861023	0.776919261684345	0.776919261684345	0.776919261684345
Rasal1	ENSMUSG00000029602	0.104514017713484	0.313542053140452	0.560630351397847	0.560630351397847	0.384286524841344	0.560630351397847
Rasgrp4	ENSMUSG00000030589	0.5155648232968	0.5155648232968	0.148772260628989	0.223158390943484	0.119631084167592	0.223158390943484
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Ets1	ENSMUSG00000032035	0.0869438727002335	0.2608316181007	0.921139684946258	0.921139684946258	0.334323804341914	0.501485706512871
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Rasal3	ENSMUSG00000052142	0.566285712787375	0.577829325134931	0.441845139428191	0.577829325134931	0.577829325134931	0.577829325134931
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887

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Rheumatoid arthritis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Ctla4	ENSMUSG00000026011	0.200650219614881	0.450143880930327	1	1	0.300095920620218	0.450143880930327
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Atp6v0d2	ENSMUSG00000028238	0.753035561236083	0.754842077504805	0.754842077504805	0.754842077504805	0.133883564214237	0.401650692642711
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Transcriptional misregulation in cancer

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tmprss2	ENSMUSG00000000385	0.501782052576058	0.501782052576058	0.108554321668226	0.325662965004679	0.454942951775341	0.501782052576058
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Spi1	ENSMUSG00000002111	0.338976281569376	0.508464422354065	0.177853449259986	0.508464422354065	0.642366752097095	0.642366752097095
Mef2c	ENSMUSG00000005583	0.749775747200219	0.752577660361457	0.679629711532125	0.752577660361457	0.752577660361457	0.752577660361457
Pax5	ENSMUSG00000014030	0.916788914239206	0.916788914239206	0.756171257307523	0.916788914239206	0.841812594759375	0.916788914239206
Fli1	ENSMUSG00000016087	1	1	0.558695769640278	1	0.921273194899708	1
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Bcl6	ENSMUSG00000022508	0.393724994268831	0.774871910813158	0.553410011703054	0.774871910813158	0.774871910813158	0.774871910813158
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Hhex	ENSMUSG00000024986	0.847317797849051	0.847317797849051	0.6275332346787	0.847317797849051	0.452880492349546	0.847317797849051
Ldb1	ENSMUSG00000025223	0.398829756175299	0.867170057724026	0.926333123228344	0.926333123228344	0.578113371816017	0.867170057724026
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Eya1	ENSMUSG00000025932	0.297472133192261	0.446208199788392	0.711034989117171	0.711034989117171	0.292909738490495	0.446208199788392
Elk4	ENSMUSG00000026436	0.0743693776059064	0.223108132817719	0.848280005680805	0.848280005680805	0.846460676830692	0.848280005680805
Traf1	ENSMUSG00000026875	0.0103546374915853	0.0155319562373779	1	1	0.00236268169165983	0.0070880450749795
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Cdk14	ENSMUSG00000028926	0.578113371816017	0.578113371816017	0.452880492349546	0.578113371816017	0.398108175780842	0.578113371816017
Lmo2	ENSMUSG00000032698	0.316009922457324	0.474014883685985	0.560950328333967	0.560950328333967	0.254787123615605	0.474014883685985
Lyl1	ENSMUSG00000034041	0.467843823235957	0.851269832762335	0.918318180260075	0.918318180260075	0.567513221841557	0.851269832762335
Bmp2k	ENSMUSG00000034663	0.710208797518812	0.7802108304765	0.7802108304765	0.7802108304765	0.179945789077372	0.539837367232115
Rara	ENSMUSG00000037992	0.179249687218049	0.537749061654148	0.92622377157404	0.92622377157404	0.78148726569172	0.92622377157404
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Foxo1	ENSMUSG00000044167	0.769866760519794	0.846460676830692	0.297848640636702	0.846460676830692	0.846460676830692	0.846460676830692
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Bcl2a1b	ENSMUSG00000089929	0.0315593554855452	0.0946780664566357	0.633039971999413	0.633039971999413	0.17924968721805	0.268874530827074

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Acute myeloid leukemia

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tcf7	ENSMUSG00000000782	1	1	0.61878896230102	0.928183443451529	0.553410011703054	0.928183443451529
Spi1	ENSMUSG00000002111	0.338976281569376	0.508464422354065	0.177853449259986	0.508464422354065	0.642366752097095	0.642366752097095
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Lef1	ENSMUSG00000027985	0.659704394429487	0.659704394429487	0.658353668475243	0.659704394429487	0.24361318058863	0.659704394429487
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Pim2	ENSMUSG00000031155	0.0763619660358786	0.229085898107636	0.45596561163947	0.45596561163947	0.254787123615605	0.382180685423408
Eif4ebp1	ENSMUSG00000031490	0.342405296020881	0.450444934184774	0.450444934184774	0.450444934184774	0.146800541856249	0.440401625568746
Rara	ENSMUSG00000037992	0.179249687218049	0.537749061654148	0.92622377157404	0.92622377157404	0.78148726569172	0.92622377157404
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Flt3	ENSMUSG00000042817	0.0268096320107596	0.0804288960322787	0.92350506192425	0.92350506192425	0.0671691953892782	0.100753793083917
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Bcl2a1b	ENSMUSG00000089929	0.0315593554855452	0.0946780664566357	0.633039971999413	0.633039971999413	0.17924968721805	0.268874530827074

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Toxoplasmosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133

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Autoimmune thyroid disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Ctla4	ENSMUSG00000026011	0.200650219614881	0.450143880930327	1	1	0.300095920620218	0.450143880930327
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Tg	ENSMUSG00000053469	0.926550375688041	0.926550375688041	0.455625354715449	0.683438032073173	0.255901190956604	0.683438032073173
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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African trypanosomiasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Kng2	ENSMUSG00000060459	0.92550091578426	0.92550091578426	0.568730419752528	0.92550091578426	0.63908115343663	0.92550091578426

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Cholinergic synapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Cacna1d	ENSMUSG00000015968	0.642864324224729	0.711650020253571	0.711650020253571	0.711650020253571	0.399548817627028	0.711650020253571
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Ache	ENSMUSG00000023328	0.578113371816017	0.578113371816017	0.454600801949285	0.578113371816017	0.248769231421035	0.578113371816017
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Camk4	ENSMUSG00000038128	0.680744598257505	0.680744598257505	0.178692663513448	0.380498235572952	0.253665490381968	0.380498235572952
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Kcnj12	ENSMUSG00000042529	0.853372965654504	0.853372965654504	0.578113371816017	0.853372965654504	0.0964252305385471	0.289275691615641
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296

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Glutamatergic synapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Slc1a2	ENSMUSG00000005089	0.573498913947369	0.638310022345193	0.638310022345193	0.638310022345193	0.452880492349546	0.638310022345193
Cacna1d	ENSMUSG00000015968	0.642864324224729	0.711650020253571	0.711650020253571	0.711650020253571	0.399548817627028	0.711650020253571
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Slc38a1	ENSMUSG00000023169	0.852504981253341	0.852504981253341	0.400265374208515	0.600398061312773	0.179945789077372	0.539837367232115
Adrbk1	ENSMUSG00000024858	0.0162664168407233	0.0333757576418323	0.0701431284016184	0.0701431284016184	0.0222505050945549	0.0333757576418323
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Shank1	ENSMUSG00000038738	0.0964252305385471	0.289275691615641	0.334323804341914	0.501485706512871	0.505838378028518	0.505838378028518
Grin3a	ENSMUSG00000039579	0.709793037667153	0.925160045487646	0.925160045487646	0.925160045487646	0.0092175830666057	0.0276527491998171
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219

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JAK-STAT signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Il27ra	ENSMUSG00000005465	0.108244222162358	0.324732666487074	1	1	0.455625354715449	0.683438032073173
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Cntfr	ENSMUSG00000028444	0.776750778128093	0.776750778128093	0.776750778128093	0.776750778128093	0.450444934184774	0.776750778128093
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Il2rg	ENSMUSG00000031304	0.0150443553124284	0.0451330659372853	0.922189155665787	0.922189155665787	0.0964252305385472	0.144637845807821
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Ccnd3	ENSMUSG00000034165	0.513026869856283	0.513026869856283	0.398108175780842	0.513026869856283	0.400265374208515	0.513026869856283
Socs5	ENSMUSG00000037104	0.297095062262362	0.450143880930327	0.300095920620218	0.450143880930327	0.853049270252403	0.853049270252403
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Osm	ENSMUSG00000058755	0.210374401237615	0.210374401237615	0.0164739112492867	0.0247108668739301	0.0160600007544847	0.0247108668739301
Csf2ra	ENSMUSG00000059326	0.577829325134931	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152	0.926658283600152
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Stat4	ENSMUSG00000062939	0.920461794456068	0.920461794456068	0.764115430291227	0.920461794456068	0.157741398767132	0.473224196301396
Il3ra	ENSMUSG00000068758	0.00749632974009822	0.0224889892202947	0.643112334413352	0.643112334413352	0.1168786685029	0.17531800275435

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Herpes simplex virus 1 infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cfp	ENSMUSG00000001128	0.0331400397096515	0.0994201191289544	0.7802108304765	0.7802108304765	0.0746183450292888	0.111927517543933
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Pou2f2	ENSMUSG00000008496	0.598933903427089	0.598933903427089	0.458890710010385	0.598933903427089	0.425792187518042	0.598933903427089
Zfp334	ENSMUSG00000017667	0.514934023620345	0.704440461749122	0.565977207415963	0.704440461749122	0.704440461749122	0.704440461749122
Srsf1	ENSMUSG00000018379	0.643853282854191	0.643853282854191	0.511742979522636	0.643853282854191	0.643359829732651	0.643853282854191
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Sp100	ENSMUSG00000026222	0.344663224299303	0.516994836448954	0.852504981253341	0.852504981253341	0.216214347033995	0.516994836448954
Traf5	ENSMUSG00000026637	0.108864301062964	0.163296451594446	0.372784277071192	0.372784277071192	0.0117179415987427	0.0351538247962282
Il12a	ENSMUSG00000027776	0.490462404969451	0.849107182150815	0.849107182150815	0.849107182150815	0.572911448356892	0.849107182150815
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Oas1b	ENSMUSG00000029605	0.0756145297453648	0.113421794618047	0.638824656785692	0.638824656785692	0.024062085667391	0.072186257002173
Zik1	ENSMUSG00000030393	0.780851835278818	0.780851835278818	0.640355507848752	0.780851835278818	0.572616808177226	0.780851835278818
Zfp275	ENSMUSG00000031365	0.850380130396972	0.850380130396972	0.327972855903273	0.681901202923927	0.454600801949285	0.681901202923927
Eif4ebp1	ENSMUSG00000031490	0.342405296020881	0.450444934184774	0.450444934184774	0.450444934184774	0.146800541856249	0.440401625568746
Mb21d1	ENSMUSG00000032344	0.577259514257969	0.577259514257969	0.507168839166081	0.577259514257969	0.299349060054895	0.577259514257969
Zfp39	ENSMUSG00000037001	0.454600801949285	0.776919261684345	0.703556284613037	0.776919261684345	0.776919261684345	0.776919261684345
Zfp113	ENSMUSG00000037007	0.455625354715449	0.78180291566155	0.78180291566155	0.78180291566155	0.643853282854191	0.78180291566155
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Zfp597	ENSMUSG00000039789	0.782117202022501	1	1	1	0.45596561163947	1
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Zfp689	ENSMUSG00000048921	0.246861959455465	0.370292939183197	0.395928178642446	0.395928178642446	0.0497293992720784	0.149188197816235
Zfp623	ENSMUSG00000050846	0.707899741868332	0.7802108304765	0.7802108304765	0.7802108304765	0.642366752097095	0.7802108304765
Zfp940	ENSMUSG00000050855	0.347269605097055	0.520904407645582	0.850948190971883	0.850948190971883	0.292141300005423	0.520904407645582
Zfp52	ENSMUSG00000051341	1	1	0.364479238287877	0.958236985178538	0.638824656785692	0.958236985178538
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
Zfp811	ENSMUSG00000055202	0.708323672944427	0.708323672944427	0.337049057953584	0.59553157669567	0.397021051130447	0.59553157669567
Zfp709	ENSMUSG00000056019	0.926550375688041	0.926550375688041	0.0897372356882883	0.269211707064865	0.57466664340579	0.861999965108685
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Gm13051	ENSMUSG00000066009	0.643359829732651	0.78148726569172	0.449391287230099	0.78148726569172	0.78148726569172	0.78148726569172
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Zfp619	ENSMUSG00000068959	0.926550375688041	0.926550375688041	0.78180291566155	0.926550375688041	0.514934023620345	0.926550375688041
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Zfp382	ENSMUSG00000074220	0.710001140920767	1	1	1	0.925948247631505	1
Gm13152	ENSMUSG00000078496	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643359829732651	0.853694531487825
Gm13212	ENSMUSG00000078502	0.776919261684345	0.776919261684345	0.00376384688812124	0.0112915406643637	0.346527959006435	0.519791938509652

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Asthma

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133

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Calcium signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
P2rx5	ENSMUSG00000005950	0.111957284180537	0.169324023937537	0.112882682625025	0.169324023937537	0.204049463366727	0.204049463366727
Cacna1d	ENSMUSG00000015968	0.642864324224729	0.711650020253571	0.711650020253571	0.711650020253571	0.399548817627028	0.711650020253571
Adora2a	ENSMUSG00000020178	0.639337105615665	0.639337105615665	0.290210015182478	0.516994836448955	0.344663224299303	0.516994836448955
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Cacna1i	ENSMUSG00000022416	0.829928232630808	0.831255031223636	0.829928232630808	0.831255031223636	0.831255031223636	0.831255031223636
Htr7	ENSMUSG00000024798	0.119020462826154	0.357061388478463	0.706401308111632	0.706401308111632	0.245711415034162	0.368567122551243
Phkg1	ENSMUSG00000025537	0.575824878403157	0.576112968612194	0.576112968612194	0.576112968612194	0.29252580908486	0.576112968612194
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Ryr1	ENSMUSG00000030592	0.924227671363131	0.924227671363131	0.702215027772976	0.924227671363131	0.568123100704554	0.924227671363131
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Phka1	ENSMUSG00000034055	0.0325051220296005	0.0975153660888016	0.283930443883615	0.283930443883615	0.134113174211452	0.201169761317178
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gna15	ENSMUSG00000034792	0.78180291566155	1	1	1	0.347639524025037	1
Tbxa2r	ENSMUSG00000034881	0.0426702157436794	0.128010647231038	0.211844580334808	0.317766870502212	0.514934023620344	0.514934023620344
Hrh2	ENSMUSG00000034987	0.0167871584516597	0.0503614753549791	0.776750778128093	0.776750778128093	0.707687082601868	0.776750778128093
Camk4	ENSMUSG00000038128	0.680744598257505	0.680744598257505	0.178692663513448	0.380498235572952	0.253665490381968	0.380498235572952
Itpkb	ENSMUSG00000038855	0.348008842235184	0.767614469283954	0.511742979522636	0.767614469283954	0.852504981253341	0.852504981253341
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Orai3	ENSMUSG00000043964	0.348008842235184	0.399548817627028	0.0753654386865988	0.226096316059796	0.399548817627028	0.399548817627028
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Adrb2	ENSMUSG00000045730	0.3147377288878	0.472106593331701	0.166129043871274	0.472106593331701	0.926550375688041	0.926550375688041
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Ntrk3	ENSMUSG00000059146	0.51398322803049	0.770974842045735	0.14712977154559	0.441389314636769	0.781645261743309	0.781645261743309
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904

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Kaposi sarcoma-associated herpesvirus infection

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tcf7	ENSMUSG00000000782	1	1	0.61878896230102	0.928183443451529	0.553410011703054	0.928183443451529
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Cd200r1	ENSMUSG00000022667	0.214037080764326	0.287873078401389	0.25141795904251	0.287873078401389	0.287873078401389	0.287873078401389
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Ccr1	ENSMUSG00000025804	0.254414773803597	0.340887582990546	0.340887582990546	0.340887582990546	0.00289311433957183	0.0086793430187155
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Lef1	ENSMUSG00000027985	0.659704394429487	0.659704394429487	0.658353668475243	0.659704394429487	0.24361318058863	0.659704394429487
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Nfatc1	ENSMUSG00000033016	0.766467256503162	0.766467256503162	0.488993143767491	0.766467256503162	0.765300177286193	0.766467256503162
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Prex1	ENSMUSG00000039621	0.0566379395854604	0.0849569093781906	0.636229315311352	0.636229315311352	0.0421101560083839	0.0849569093781906
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976

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Regulation of actin cytoskeleton

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Pip4k2b	ENSMUSG00000018547	0.393724994268831	0.590587491403246	0.642366752097095	0.642366752097095	0.246861959455465	0.590587491403246
Cyfip2	ENSMUSG00000020340	0.605446529449261	0.921139684946258	0.764115430291227	0.921139684946258	0.921139684946258	0.921139684946258
Nckap1l	ENSMUSG00000022488	0.0548979200435555	0.0823468800653333	1	1	0.0110666956860337	0.0332000870581011
Itgb8	ENSMUSG00000025321	0.686937109830067	1	0.412182162844325	1	1	1
Pdgfa	ENSMUSG00000025856	0.024062085667391	0.072186257002173	0.209636747299872	0.314455120949809	0.711034989117171	0.711034989117171
Pip4k2a	ENSMUSG00000026737	0.283930443883615	0.751644504901775	0.501096336601183	0.751644504901775	1	1
Arpc5l	ENSMUSG00000026755	1	1	0.255530331334266	0.766590994002797	0.853372965654504	1
Itga4	ENSMUSG00000027009	0.757910339741814	0.839747317770595	0.839747317770595	0.839747317770595	0.170434860179341	0.511304580538024
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Mylpf	ENSMUSG00000030672	0.397384062266614	0.596076093399921	0.214037080764326	0.596076093399921	0.707899741868332	0.707899741868332
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Arhgef6	ENSMUSG00000031133	0.43283647035887	0.638824656785692	0.505169133438821	0.638824656785692	0.638824656785692	0.638824656785692
Msn	ENSMUSG00000031207	0.283930443883615	0.342405296020882	0.342405296020882	0.342405296020882	0.245326864841171	0.342405296020882
Lpar2	ENSMUSG00000031861	0.513026869856283	0.513026869856283	0.297095062262363	0.445642593393545	0.0741204440774084	0.222361332232225
Rdx	ENSMUSG00000032050	0.5155648232968	0.576112968612194	0.252545530864481	0.576112968612194	0.576112968612194	0.576112968612194
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Arhgef4	ENSMUSG00000037509	0.508817043656047	0.632770400279953	0.632770400279953	0.632770400279953	0.209267277690899	0.627801833072696
Fgd3	ENSMUSG00000037946	0.0886202385494145	0.265860715648244	0.505169133438821	0.505169133438821	0.34837756124189	0.505169133438821
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Arhgef1	ENSMUSG00000040940	0.92392908126717	0.92392908126717	0.774176834800231	0.92392908126717	0.248769231421035	0.746307694263104
Cxcr4	ENSMUSG00000045382	0.69302991927204	0.69302991927204	0.623528016403391	0.69302991927204	0.450794830295118	0.69302991927204
Kng2	ENSMUSG00000060459	0.92550091578426	0.92550091578426	0.568730419752528	0.92550091578426	0.63908115343663	0.92550091578426
Cxcl12	ENSMUSG00000061353	0.455625354715448	0.683438032073173	0.453225835454266	0.683438032073173	0.853372965654504	0.853372965654504

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FoxO signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Stk4	ENSMUSG00000018209	0.781170242226513	0.78180291566155	0.78180291566155	0.78180291566155	0.207413485884613	0.62224045765384
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Gadd45g	ENSMUSG00000021453	0.924987846321933	0.925444427431699	0.925444427431699	0.925444427431699	0.640861491578951	0.925444427431699
Bcl6	ENSMUSG00000022508	0.393724994268831	0.774871910813158	0.553410011703054	0.774871910813158	0.774871910813158	0.774871910813158
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Agap2	ENSMUSG00000025422	0.31685435697757	0.475281535466355	1	1	0.0100680871404542	0.0302042614213625
Sgk3	ENSMUSG00000025915	0.926658283600152	0.926658283600152	0.21549027811633	0.64647083434899	0.452880492349546	0.679320738524319
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Foxo1	ENSMUSG00000044167	0.769866760519794	0.846460676830692	0.297848640636702	0.846460676830692	0.846460676830692	0.846460676830692
S1pr4	ENSMUSG00000044199	0.178287767933578	0.534863303800733	0.424592967853335	0.636889451780002	0.781011212316137	0.781011212316137
S1pr1	ENSMUSG00000045092	0.628654363853655	0.628654363853655	0.384672302267076	0.577008453400614	0.293293089483362	0.577008453400614
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Klf2	ENSMUSG00000055148	0.776243028387552	0.776919261684345	0.43283647035887	0.776919261684345	0.776919261684345	0.776919261684345
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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Viral myocarditis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
H2-T24	ENSMUSG00000053835	0.162867964743396	0.488603894230187	0.501096336601183	0.501096336601183	0.342026805366747	0.501096336601183
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Chst15	ENSMUSG00000030930	0.298974794311434	0.640101714462795	0.45596561163947	0.640101714462795	0.640101714462795	0.640101714462795
Chsy1	ENSMUSG00000032640	0.21494612068098	0.644838362042941	0.690028363829288	1	1	1
Chst11	ENSMUSG00000034612	0.0953125666339396	0.252969978550618	0.850721744111585	0.850721744111585	0.168646652367079	0.252969978550618
Csgalnact2	ENSMUSG00000042042	0.926550375688041	0.926550375688041	0.712057867818062	0.926550375688041	0.0579478375430677	0.173843512629203
Chst3	ENSMUSG00000057337	0.755951227598167	1	0.836715131145005	1	1	1

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Phosphatidylinositol signaling system

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Pip4k2b	ENSMUSG00000018547	0.393724994268831	0.590587491403246	0.642366752097095	0.642366752097095	0.246861959455465	0.590587491403246
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Pip4k2a	ENSMUSG00000026737	0.283930443883615	0.751644504901775	0.501096336601183	0.751644504901775	1	1
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Inpp4b	ENSMUSG00000037940	0.633039971999413	0.633039971999413	0.141500034183268	0.222173997210624	0.148115998140416	0.222173997210624
Itpkb	ENSMUSG00000038855	0.348008842235184	0.767614469283954	0.511742979522636	0.767614469283954	0.852504981253341	0.852504981253341
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Inpp5f	ENSMUSG00000042105	0.400265374208515	0.600398061312773	0.925444427431699	0.925444427431699	0.343537039781257	0.600398061312773
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Dgkk	ENSMUSG00000062393	1	1	0.18271676270485	0.54815028811455	1	1

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Relaxin signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Adcy7	ENSMUSG00000031659	0.294820734456232	0.442231101684348	0.84934104438081	0.84934104438081	0.0701431284016185	0.210429385204856
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Gna15	ENSMUSG00000034792	0.78180291566155	1	1	1	0.347639524025037	1
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Arrb2	ENSMUSG00000060216	1	1	0.5155648232968	0.7733472349452	0.17750354896016	0.53251064688048

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Long-term potentiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Ppp3cc	ENSMUSG00000022092	0.629211154902385	0.923321156062851	0.923321156062851	0.923321156062851	0.57113445032749	0.923321156062851
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Camk4	ENSMUSG00000038128	0.680744598257505	0.680744598257505	0.178692663513448	0.380498235572952	0.253665490381968	0.380498235572952
Plcb4	ENSMUSG00000039943	0.346899083932133	1	0.782117202022501	1	1	1
Plcb2	ENSMUSG00000040061	0.711034989117171	0.711034989117171	0.255530331334266	0.383295497001398	0.00468160475316414	0.0140448142594924
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Icosl	ENSMUSG00000000732	1	1	0.922317414627388	1	0.0743693776059063	0.223108132817719
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Cfp	ENSMUSG00000001128	0.0331400397096515	0.0994201191289544	0.7802108304765	0.7802108304765	0.0746183450292888	0.111927517543933
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Il16	ENSMUSG00000001741	0.270898788519615	0.6275332346787	0.6275332346787	0.6275332346787	0.573791743469336	0.6275332346787
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ap1m1	ENSMUSG00000003033	1	1	1	1	0.0753654386865989	0.226096316059797
Slc2a3	ENSMUSG00000003153	0.148115998140416	0.444347994421247	0.578113371816017	0.578113371816017	0.514934023620345	0.578113371816017
Ebi3	ENSMUSG00000003206	0.147458757705094	0.221188136557642	0.00768144932639892	0.0230443479791968	0.85117361048289	0.85117361048289
Cd79a	ENSMUSG00000003379	0.43283647035887	0.852832278580641	0.624685493301961	0.852832278580641	0.852832278580641	0.852832278580641
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Hmox2	ENSMUSG00000004070	0.78148726569172	0.926658283600152	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Ctse	ENSMUSG00000004552	0.213307944885796	0.319961917328694	0.711034989117171	0.711034989117171	0.0575107614292586	0.172532284287776
Cnn2	ENSMUSG00000004665	0.269223850346639	0.443306001726868	0.443306001726868	0.443306001726868	0.43283647035887	0.443306001726868
Abca13	ENSMUSG00000004668	0.39335551479284	0.51270683838022	0.247244441753849	0.51270683838022	0.51270683838022	0.51270683838022
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Il27ra	ENSMUSG00000005465	0.108244222162358	0.324732666487074	1	1	0.455625354715449	0.683438032073173
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Trpm2	ENSMUSG00000009292	0.0880615565264046	0.132092334789607	0.7802108304765	0.7802108304765	0.0763619660358787	0.132092334789607
Lpo	ENSMUSG00000009356	1	1	0.826290760660065	1	0.826290760660065	1
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
1810033B17Rik	ENSMUSG00000013974	0.123175587755902	0.255438305988142	0.255438305988142	0.255438305988142	0.189061599254104	0.255438305988142
Slamf6	ENSMUSG00000015314	0.458890710010385	0.603084091822085	0.603084091822085	0.603084091822085	0.117975613258695	0.353926839776085
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ager	ENSMUSG00000015452	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.400265374208515	0.600398061312773
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Myo1c	ENSMUSG00000017774	0.216214347033995	0.324321520550992	0.926441990075769	0.926441990075769	0.21549027811633	0.324321520550992
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Tnfaip3	ENSMUSG00000019850	0.400265374208515	0.400265374208515	0.400265374208515	0.400265374208515	0.211110344399808	0.400265374208515
Dock2	ENSMUSG00000020143	0.27871391172685	0.675141569480709	0.692783110017144	0.692783110017144	0.450094379653806	0.675141569480709
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
Cyfip2	ENSMUSG00000020340	0.605446529449261	0.921139684946258	0.764115430291227	0.921139684946258	0.921139684946258	0.921139684946258
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Ly86	ENSMUSG00000021423	0.0982637960387657	0.294791388116297	0.535589379512136	0.803384069268203	0.926604389137101	0.926604389137101
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Lpcat1	ENSMUSG00000021608	0.144820068500793	0.21723010275119	0.246861959455465	0.246861959455465	0.0548979200435556	0.164693760130667
Cd180	ENSMUSG00000021624	0.529816072081339	1	1	1	0.766467256503162	1
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Clu	ENSMUSG00000022037	0.279118898313835	0.710416009055326	0.486016534591995	0.710416009055326	0.710416009055326	0.710416009055326
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Sla	ENSMUSG00000022372	0.195291845935736	0.292937768903604	0.920461794456068	0.920461794456068	0.0434194723707709	0.130258417112313
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Nckap1l	ENSMUSG00000022488	0.0548979200435555	0.0823468800653333	1	1	0.0110666956860337	0.0332000870581011
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Cd96	ENSMUSG00000022657	0.113498953177704	0.340496859533111	0.291756209988535	0.437634314982803	0.452880492349546	0.452880492349546
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Adam8	ENSMUSG00000025473	0.179945789077372	0.269918683616058	0.712057867818062	0.712057867818062	0.0753654386865988	0.226096316059796
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Fcna	ENSMUSG00000026938	0.926658283600152	0.926658283600152	0.514934023620345	0.772401035430517	0.299349060054895	0.772401035430517
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Pag1	ENSMUSG00000027508	0.502464977245519	0.502464977245519	0.236337185850513	0.35450577877577	0.214037080764325	0.35450577877577
Fabp5	ENSMUSG00000027533	0.378414240914692	0.450794830295118	0.388491809581663	0.450794830295118	0.450794830295118	0.450794830295118
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Dhx36	ENSMUSG00000027770	0.347639524025037	0.521459286037555	0.643853282854191	0.643853282854191	0.345410946355104	0.521459286037555
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Fbxw7	ENSMUSG00000028086	0.392985378348026	0.567513221841557	0.393724994268831	0.567513221841557	0.567513221841557	0.567513221841557
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Atp6v0d2	ENSMUSG00000028238	0.753035561236083	0.754842077504805	0.754842077504805	0.754842077504805	0.133883564214237	0.401650692642711
Tnfsf8	ENSMUSG00000028362	0.307838294631065	0.354081512249118	0.354081512249118	0.354081512249118	0.264135602004534	0.354081512249118
Cntfr	ENSMUSG00000028444	0.776750778128093	0.776750778128093	0.776750778128093	0.776750778128093	0.450444934184774	0.776750778128093
Tnfrsf8	ENSMUSG00000028602	0.253668577981715	0.253668577981715	0.176451829330851	0.253668577981715	0.00468160475316412	0.0140448142594924
Padi2	ENSMUSG00000028927	0.845337155620795	0.845337155620795	0.497625221907634	0.746437832861452	0.0232795908282423	0.0698387724847269
Kcnab2	ENSMUSG00000028931	0.329176790045262	0.493765185067894	0.707899741868332	0.707899741868332	0.297848640636703	0.493765185067894
Tnfrsf9	ENSMUSG00000028965	0.329576740674783	0.504410496659194	0.843929879174112	0.843929879174112	0.336273664439462	0.504410496659194
Masp2	ENSMUSG00000028979	0.641113685658649	0.641113685658649	0.25141795904251	0.377126938563765	0.0211129141819614	0.0633387425458841
Rhof	ENSMUSG00000029449	0.0964252305385474	0.144637845807821	0.643853282854191	0.643853282854191	0.0958690133561599	0.144637845807821
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Clec5a	ENSMUSG00000029915	0.249907451332337	0.643853282854191	0.509144723230069	0.643853282854191	0.643853282854191	0.643853282854191
Clec4d	ENSMUSG00000030144	0.444032220827359	0.666048331241038	0.775389027507362	0.775389027507362	0.246095446958788	0.666048331241038
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
Cd27	ENSMUSG00000030336	0.328374849423202	0.642864324224729	0.615734841980377	0.642864324224729	0.642864324224729	0.642864324224729
Lilra6	ENSMUSG00000030427	0.168646652367078	0.252969978550618	0.437393870295853	0.437393870295853	0.000333936947699979	0.00100181084309994
Siglecg	ENSMUSG00000030468	0.68129770017266	0.777922216623952	0.758766047369853	0.777922216623952	0.777922216623952	0.777922216623952
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Ap1s2	ENSMUSG00000031367	0.853049270252403	0.853049270252403	0.177853449259986	0.533560347779959	0.643853282854191	0.853049270252403
Dusp4	ENSMUSG00000031530	0.781011212316137	0.781011212316137	0.576687400573867	0.781011212316137	0.145811394942709	0.437434184828127
Crtam	ENSMUSG00000032021	0.0226344734406829	0.0679034203220487	0.343537039781257	0.515305559671886	0.926658283600152	0.926658283600152
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Icam5	ENSMUSG00000032174	0.71082910328023	0.78132892626786	0.78132892626786	0.78132892626786	0.578113371816017	0.78132892626786
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Kif9	ENSMUSG00000032489	0.853694531487825	0.853694531487825	0.853694531487825	0.853694531487825	0.144157978128026	0.432473934384077
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Myo5a	ENSMUSG00000034593	0.851732715229127	0.852175490580835	0.852175490580835	0.852175490580835	0.77858338846904	0.852175490580835
Fbxl21	ENSMUSG00000035509	0.0334587898203823	0.100376369461147	0.252920381501207	0.37938057225181	0.511097249598474	0.511097249598474
Hmha1	ENSMUSG00000035697	0.1540397616999	0.462119285099701	0.920735042422376	0.920735042422376	0.454942951775341	0.682414427663012
Dok3	ENSMUSG00000035711	0.610047953449801	0.610047953449801	0.542246307846122	0.610047953449801	0.395928178642446	0.610047953449801
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Cyld	ENSMUSG00000036712	0.852940894477647	0.852940894477647	0.447265995733381	0.675667401277161	0.450444934184774	0.675667401277161
Socs5	ENSMUSG00000037104	0.297095062262362	0.450143880930327	0.300095920620218	0.450143880930327	0.853049270252403	0.853049270252403
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Mylip	ENSMUSG00000038175	0.71082910328023	0.71082910328023	0.287481513930451	0.71082910328023	0.640608766263372	0.71082910328023
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Klhl42	ENSMUSG00000040102	0.344288444541856	0.861125960300578	0.574083973533718	0.861125960300578	0.92589277149125	0.92589277149125
Tbc1d10c	ENSMUSG00000040247	0.187486171644953	0.449023590082343	0.762100360299702	0.762100360299702	0.299349060054895	0.449023590082343
Arhgap9	ENSMUSG00000040345	0.0109864933352154	0.0329594800056461	0.6275332346787	0.78180291566155	0.78180291566155	0.78180291566155
Cd79b	ENSMUSG00000040592	0.189061599254104	0.567184797762312	0.607438359373598	0.849805525376199	0.849805525376199	0.849805525376199
Clcf1	ENSMUSG00000040663	0.769866760519794	0.769866760519794	0.566285712787375	0.769866760519794	0.300095920620218	0.769866760519794
Cd53	ENSMUSG00000040747	0.119713811475365	0.179570717213048	0.91861403840811	0.91861403840811	0.0746183450292887	0.179570717213048
Lat2	ENSMUSG00000040751	0.364479238287877	0.670898993600072	1	1	0.447265995733381	0.670898993600072
Sh3kbp1	ENSMUSG00000040990	0.443306001726868	0.568427079091759	0.568427079091759	0.568427079091759	0.501782052576058	0.568427079091759
Elmo1	ENSMUSG00000041112	0.179945789077372	0.51755608657933	0.926550375688041	0.926550375688041	0.345037391052887	0.51755608657933
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Tnfrsf18	ENSMUSG00000041954	0.109793509122179	0.329380527366537	0.776919261684345	0.776919261684345	0.5155648232968	0.7733472349452
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Hecw2	ENSMUSG00000042807	0.696899768923163	0.696899768923163	0.0196307077218453	0.0588921231655358	0.0599532724680346	0.0899299087020519
Tlr7	ENSMUSG00000044583	0.705752031336119	0.781011212316137	0.706401308111632	0.781011212316137	0.781011212316137	0.781011212316137
Tlr1	ENSMUSG00000044827	0.17610058307789	0.264150874616835	0.0331400397096515	0.0994201191289544	0.781170242226513	0.781170242226513
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Plaur	ENSMUSG00000046223	0.17750354896016	0.256271555563966	0.256271555563966	0.256271555563966	0.148115998140416	0.256271555563966
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Plekho2	ENSMUSG00000050721	0.0928059258606269	0.278417777581881	0.924814453025535	0.924814453025535	0.332752104054419	0.499128156081629
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Treml4	ENSMUSG00000051682	0.398469281729516	0.640608766263372	0.640608766263372	0.640608766263372	0.574375606171923	0.640608766263372
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Tnfaip6	ENSMUSG00000053475	0.169362944517671	0.508088833553014	0.641867098978197	0.641867098978197	0.398108175780842	0.597162263671263
Dusp7	ENSMUSG00000053716	0.45596561163947	0.683948417459205	1	1	0.298974794311434	0.683948417459205
Ap1s3	ENSMUSG00000054702	0.400265374208515	0.769540304784424	1	1	0.513026869856283	0.769540304784424
Defb42	ENSMUSG00000054763	0.288759723436367	0.288759723436367	0.0655239237496977	0.196571771249093	0.197878158231863	0.288759723436367
Txk	ENSMUSG00000054892	0.0897372356882883	0.269211707064865	0.852832278580641	0.852832278580641	0.399548817627028	0.599323226440542
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Glipr1	ENSMUSG00000056888	1	1	0.575536202757516	0.863304304136274	0.214037080764326	0.642111242292977
Slc44a2	ENSMUSG00000057193	0.0637129576330108	0.191138872899032	0.479905817228256	0.479905817228256	0.241062360270009	0.361593540405014
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Unc13d	ENSMUSG00000057948	0.781170242226513	0.781170242226513	0.25141795904251	0.754253877127531	0.514300775319626	0.771451162979439
Osm	ENSMUSG00000058755	0.210374401237615	0.210374401237615	0.0164739112492867	0.0247108668739301	0.0160600007544847	0.0247108668739301
Ifitm6	ENSMUSG00000059108	0.0367873939579746	0.110362181873924	0.57113445032749	0.856701675491234	0.9255572759333	0.9255572759333
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Atp8b4	ENSMUSG00000060131	0.091132699670031	0.136699049505046	0.574375606171923	0.574375606171923	0.0758636487647837	0.136699049505046
Ifitm2	ENSMUSG00000060591	0.29558111906036	0.708534948098331	0.633577343537212	0.708534948098331	0.708534948098331	0.708534948098331
Gmfg	ENSMUSG00000060791	0.777255087907932	0.924872384323463	0.924872384323463	0.924872384323463	0.338976281569376	0.924872384323463
Prcp	ENSMUSG00000061119	0.167929015438905	0.503787046316716	0.778253541606068	0.778253541606068	0.346527959006435	0.519791938509652
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
Chi3l1	ENSMUSG00000064246	0.45596561163947	0.45596561163947	0.252545530864481	0.450143880930327	0.300095920620218	0.450143880930327
Hvcn1	ENSMUSG00000064267	0.1811125429711	0.431809617602084	0.689264132039392	0.689264132039392	0.287873078401389	0.431809617602084
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Lyz2	ENSMUSG00000069516	0.0328221470541517	0.098466441162455	0.6978446011211	0.707899741868332	0.707899741868332	0.707899741868332
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887
Treml2	ENSMUSG00000071068	0.45713435082887	0.685701526243305	0.757262551816799	0.757262551816799	0.150680196006792	0.452040588020377
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
C5ar2	ENSMUSG00000074361	0.119631084167592	0.358893252502775	0.707687082601868	0.707687082601868	0.632770400279953	0.707687082601868
Gm14548	ENSMUSG00000074417	0.686149754455511	0.686149754455511	0.247825081352574	0.371737622028861	0.00814448596985833	0.024433457909575
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934
Wipf1	ENSMUSG00000075284	0.55205880554923	0.55205880554923	0.505169133438821	0.55205880554923	0.371967876858695	0.55205880554923
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Ighg2c	ENSMUSG00000076612	0.275861418394615	0.413792127591923	0.766080166042519	0.766080166042519	0.0897372356882884	0.269211707064865
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972
Gm5077	ENSMUSG00000079343	0.626117476225324	0.774351207035292	0.479516713772622	0.774351207035292	0.774351207035292	0.774351207035292
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667
Pglyrp2	ENSMUSG00000079563	0.112265881554681	0.168398822332022	0.566593564630738	0.566593564630738	0.0158546704257247	0.047564011277174
Cd101	ENSMUSG00000086564	0.0331400397096515	0.0994201191289545	0.148115998140415	0.21549027811633	0.21549027811633	0.21549027811633
Pira2	ENSMUSG00000089942	0.553410011703054	0.553410011703054	0.388491809581663	0.553410011703054	0.511742979522636	0.553410011703054

Download data as csv

Generation of second messenger molecules

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
Cd101	ENSMUSG00000086564	0.0331400397096515	0.0994201191289545	0.148115998140415	0.21549027811633	0.21549027811633	0.21549027811633

Download data as csv

Phosphorylation of CD3 and TCR zeta chains

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Pag1	ENSMUSG00000027508	0.502464977245519	0.502464977245519	0.236337185850513	0.35450577877577	0.214037080764325	0.35450577877577
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Costimulation by the CD28 family

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Icosl	ENSMUSG00000000732	1	1	0.922317414627388	1	0.0743693776059063	0.223108132817719
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Innate Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Cfp	ENSMUSG00000001128	0.0331400397096515	0.0994201191289544	0.7802108304765	0.7802108304765	0.0746183450292888	0.111927517543933
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ap1m1	ENSMUSG00000003033	1	1	1	1	0.0753654386865989	0.226096316059797
Slc2a3	ENSMUSG00000003153	0.148115998140416	0.444347994421247	0.578113371816017	0.578113371816017	0.514934023620345	0.578113371816017
Hmox2	ENSMUSG00000004070	0.78148726569172	0.926658283600152	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cnn2	ENSMUSG00000004665	0.269223850346639	0.443306001726868	0.443306001726868	0.443306001726868	0.43283647035887	0.443306001726868
Abca13	ENSMUSG00000004668	0.39335551479284	0.51270683838022	0.247244441753849	0.51270683838022	0.51270683838022	0.51270683838022
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Trpm2	ENSMUSG00000009292	0.0880615565264046	0.132092334789607	0.7802108304765	0.7802108304765	0.0763619660358787	0.132092334789607
Lpo	ENSMUSG00000009356	1	1	0.826290760660065	1	0.826290760660065	1
1810033B17Rik	ENSMUSG00000013974	0.123175587755902	0.255438305988142	0.255438305988142	0.255438305988142	0.189061599254104	0.255438305988142
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ager	ENSMUSG00000015452	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.400265374208515	0.600398061312773
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Myo1c	ENSMUSG00000017774	0.216214347033995	0.324321520550992	0.926441990075769	0.926441990075769	0.21549027811633	0.324321520550992
Tnfaip3	ENSMUSG00000019850	0.400265374208515	0.400265374208515	0.400265374208515	0.400265374208515	0.211110344399808	0.400265374208515
Dock2	ENSMUSG00000020143	0.27871391172685	0.675141569480709	0.692783110017144	0.692783110017144	0.450094379653806	0.675141569480709
Cyfip2	ENSMUSG00000020340	0.605446529449261	0.921139684946258	0.764115430291227	0.921139684946258	0.921139684946258	0.921139684946258
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Ly86	ENSMUSG00000021423	0.0982637960387657	0.294791388116297	0.535589379512136	0.803384069268203	0.926604389137101	0.926604389137101
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Lpcat1	ENSMUSG00000021608	0.144820068500793	0.21723010275119	0.246861959455465	0.246861959455465	0.0548979200435556	0.164693760130667
Cd180	ENSMUSG00000021624	0.529816072081339	1	1	1	0.766467256503162	1
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Clu	ENSMUSG00000022037	0.279118898313835	0.710416009055326	0.486016534591995	0.710416009055326	0.710416009055326	0.710416009055326
Nckap1l	ENSMUSG00000022488	0.0548979200435555	0.0823468800653333	1	1	0.0110666956860337	0.0332000870581011
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Adam8	ENSMUSG00000025473	0.179945789077372	0.269918683616058	0.712057867818062	0.712057867818062	0.0753654386865988	0.226096316059796
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Fcna	ENSMUSG00000026938	0.926658283600152	0.926658283600152	0.514934023620345	0.772401035430517	0.299349060054895	0.772401035430517
Fabp5	ENSMUSG00000027533	0.378414240914692	0.450794830295118	0.388491809581663	0.450794830295118	0.450794830295118	0.450794830295118
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Dhx36	ENSMUSG00000027770	0.347639524025037	0.521459286037555	0.643853282854191	0.643853282854191	0.345410946355104	0.521459286037555
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Atp6v0d2	ENSMUSG00000028238	0.753035561236083	0.754842077504805	0.754842077504805	0.754842077504805	0.133883564214237	0.401650692642711
Padi2	ENSMUSG00000028927	0.845337155620795	0.845337155620795	0.497625221907634	0.746437832861452	0.0232795908282423	0.0698387724847269
Kcnab2	ENSMUSG00000028931	0.329176790045262	0.493765185067894	0.707899741868332	0.707899741868332	0.297848640636703	0.493765185067894
Masp2	ENSMUSG00000028979	0.641113685658649	0.641113685658649	0.25141795904251	0.377126938563765	0.0211129141819614	0.0633387425458841
Rhof	ENSMUSG00000029449	0.0964252305385474	0.144637845807821	0.643853282854191	0.643853282854191	0.0958690133561599	0.144637845807821
Limk1	ENSMUSG00000029674	0.569937449249116	0.709375484777034	0.709375484777034	0.709375484777034	0.058823267388015	0.176469802164045
Clec5a	ENSMUSG00000029915	0.249907451332337	0.643853282854191	0.509144723230069	0.643853282854191	0.643853282854191	0.643853282854191
Clec4d	ENSMUSG00000030144	0.444032220827359	0.666048331241038	0.775389027507362	0.775389027507362	0.246095446958788	0.666048331241038
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
Lilra6	ENSMUSG00000030427	0.168646652367078	0.252969978550618	0.437393870295853	0.437393870295853	0.000333936947699979	0.00100181084309994
Siglecg	ENSMUSG00000030468	0.68129770017266	0.777922216623952	0.758766047369853	0.777922216623952	0.777922216623952	0.777922216623952
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Dusp4	ENSMUSG00000031530	0.781011212316137	0.781011212316137	0.576687400573867	0.781011212316137	0.145811394942709	0.437434184828127
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Myo5a	ENSMUSG00000034593	0.851732715229127	0.852175490580835	0.852175490580835	0.852175490580835	0.77858338846904	0.852175490580835
Hmha1	ENSMUSG00000035697	0.1540397616999	0.462119285099701	0.920735042422376	0.920735042422376	0.454942951775341	0.682414427663012
Dok3	ENSMUSG00000035711	0.610047953449801	0.610047953449801	0.542246307846122	0.610047953449801	0.395928178642446	0.610047953449801
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Cyld	ENSMUSG00000036712	0.852940894477647	0.852940894477647	0.447265995733381	0.675667401277161	0.450444934184774	0.675667401277161
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Tbc1d10c	ENSMUSG00000040247	0.187486171644953	0.449023590082343	0.762100360299702	0.762100360299702	0.299349060054895	0.449023590082343
Arhgap9	ENSMUSG00000040345	0.0109864933352154	0.0329594800056461	0.6275332346787	0.78180291566155	0.78180291566155	0.78180291566155
Cd53	ENSMUSG00000040747	0.119713811475365	0.179570717213048	0.91861403840811	0.91861403840811	0.0746183450292887	0.179570717213048
Lat2	ENSMUSG00000040751	0.364479238287877	0.670898993600072	1	1	0.447265995733381	0.670898993600072
Elmo1	ENSMUSG00000041112	0.179945789077372	0.51755608657933	0.926550375688041	0.926550375688041	0.345037391052887	0.51755608657933
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Tlr7	ENSMUSG00000044583	0.705752031336119	0.781011212316137	0.706401308111632	0.781011212316137	0.781011212316137	0.781011212316137
Tlr1	ENSMUSG00000044827	0.17610058307789	0.264150874616835	0.0331400397096515	0.0994201191289544	0.781170242226513	0.781170242226513
Tlr9	ENSMUSG00000045322	0.537840295680835	0.818204825744981	0.843277382648068	0.843277382648068	0.545469883829987	0.818204825744981
Plaur	ENSMUSG00000046223	0.17750354896016	0.256271555563966	0.256271555563966	0.256271555563966	0.148115998140416	0.256271555563966
Plekho2	ENSMUSG00000050721	0.0928059258606269	0.278417777581881	0.924814453025535	0.924814453025535	0.332752104054419	0.499128156081629
Tlr6	ENSMUSG00000051498	0.147458757705094	0.221188136557642	0.451144069999285	0.451144069999285	0.0540308994052097	0.162092698215629
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Tnfaip6	ENSMUSG00000053475	0.169362944517671	0.508088833553014	0.641867098978197	0.641867098978197	0.398108175780842	0.597162263671263
Dusp7	ENSMUSG00000053716	0.45596561163947	0.683948417459205	1	1	0.298974794311434	0.683948417459205
Defb42	ENSMUSG00000054763	0.288759723436367	0.288759723436367	0.0655239237496977	0.196571771249093	0.197878158231863	0.288759723436367
Txk	ENSMUSG00000054892	0.0897372356882883	0.269211707064865	0.852832278580641	0.852832278580641	0.399548817627028	0.599323226440542
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Glipr1	ENSMUSG00000056888	1	1	0.575536202757516	0.863304304136274	0.214037080764326	0.642111242292977
Slc44a2	ENSMUSG00000057193	0.0637129576330108	0.191138872899032	0.479905817228256	0.479905817228256	0.241062360270009	0.361593540405014
Bcl2	ENSMUSG00000057329	0.92380865295296	0.92380865295296	0.637274134311157	0.92380865295296	0.635703516568382	0.92380865295296
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Unc13d	ENSMUSG00000057948	0.781170242226513	0.781170242226513	0.25141795904251	0.754253877127531	0.514300775319626	0.771451162979439
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Atp8b4	ENSMUSG00000060131	0.091132699670031	0.136699049505046	0.574375606171923	0.574375606171923	0.0758636487647837	0.136699049505046
Gmfg	ENSMUSG00000060791	0.777255087907932	0.924872384323463	0.924872384323463	0.924872384323463	0.338976281569376	0.924872384323463
Prcp	ENSMUSG00000061119	0.167929015438905	0.503787046316716	0.778253541606068	0.778253541606068	0.346527959006435	0.519791938509652
Chi3l1	ENSMUSG00000064246	0.45596561163947	0.45596561163947	0.252545530864481	0.450143880930327	0.300095920620218	0.450143880930327
Hvcn1	ENSMUSG00000064267	0.1811125429711	0.431809617602084	0.689264132039392	0.689264132039392	0.287873078401389	0.431809617602084
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Lyz2	ENSMUSG00000069516	0.0328221470541517	0.098466441162455	0.6978446011211	0.707899741868332	0.707899741868332	0.707899741868332
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
C5ar2	ENSMUSG00000074361	0.119631084167592	0.358893252502775	0.707687082601868	0.707687082601868	0.632770400279953	0.707687082601868
Gm14548	ENSMUSG00000074417	0.686149754455511	0.686149754455511	0.247825081352574	0.371737622028861	0.00814448596985833	0.024433457909575
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062
Wipf1	ENSMUSG00000075284	0.55205880554923	0.55205880554923	0.505169133438821	0.55205880554923	0.371967876858695	0.55205880554923
Ighg2c	ENSMUSG00000076612	0.275861418394615	0.413792127591923	0.766080166042519	0.766080166042519	0.0897372356882884	0.269211707064865
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972
Gm5077	ENSMUSG00000079343	0.626117476225324	0.774351207035292	0.479516713772622	0.774351207035292	0.774351207035292	0.774351207035292
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667
Pglyrp2	ENSMUSG00000079563	0.112265881554681	0.168398822332022	0.566593564630738	0.566593564630738	0.0158546704257247	0.047564011277174
Pira2	ENSMUSG00000089942	0.553410011703054	0.553410011703054	0.388491809581663	0.553410011703054	0.511742979522636	0.553410011703054

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PD-1 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Pag1	ENSMUSG00000027508	0.502464977245519	0.502464977245519	0.236337185850513	0.35450577877577	0.214037080764325	0.35450577877577
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972
Cd101	ENSMUSG00000086564	0.0331400397096515	0.0994201191289545	0.148115998140415	0.21549027811633	0.21549027811633	0.21549027811633

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Adaptive Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Icosl	ENSMUSG00000000732	1	1	0.922317414627388	1	0.0743693776059063	0.223108132817719
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ap1m1	ENSMUSG00000003033	1	1	1	1	0.0753654386865989	0.226096316059797
Cd79a	ENSMUSG00000003379	0.43283647035887	0.852832278580641	0.624685493301961	0.852832278580641	0.852832278580641	0.852832278580641
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Ctse	ENSMUSG00000004552	0.213307944885796	0.319961917328694	0.711034989117171	0.711034989117171	0.0575107614292586	0.172532284287776
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Slamf6	ENSMUSG00000015314	0.458890710010385	0.603084091822085	0.603084091822085	0.603084091822085	0.117975613258695	0.353926839776085
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Itk	ENSMUSG00000020395	0.364479238287877	0.624108087819719	0.624108087819719	0.624108087819719	0.563485358844814	0.624108087819719
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Ppp3cb	ENSMUSG00000021816	0.147458757705094	0.442376273115283	0.397384062266614	0.596076093399921	0.641867098978197	0.641867098978197
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Cd96	ENSMUSG00000022657	0.113498953177704	0.340496859533111	0.291756209988535	0.437634314982803	0.452880492349546	0.452880492349546
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Nfkbie	ENSMUSG00000023947	0.0852666932085726	0.255800079625718	0.770602256086003	0.770602256086003	0.216214347033995	0.324321520550992
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
H2-Oa	ENSMUSG00000024334	0.203668289658219	0.40611577256979	0.40611577256979	0.40611577256979	0.388491809581663	0.40611577256979
Icos	ENSMUSG00000026009	0.179097106824913	0.268645660237369	0.309146821891444	0.309146821891444	0.119325847749354	0.268645660237369
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Pag1	ENSMUSG00000027508	0.502464977245519	0.502464977245519	0.236337185850513	0.35450577877577	0.214037080764325	0.35450577877577
Nfatc2	ENSMUSG00000027544	0.558695769640278	0.622945258536671	0.622945258536671	0.622945258536671	0.162867964743396	0.488603894230187
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Fbxw7	ENSMUSG00000028086	0.392985378348026	0.567513221841557	0.393724994268831	0.567513221841557	0.567513221841557	0.567513221841557
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Siglecg	ENSMUSG00000030468	0.68129770017266	0.777922216623952	0.758766047369853	0.777922216623952	0.777922216623952	0.777922216623952
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Ap1s2	ENSMUSG00000031367	0.853049270252403	0.853049270252403	0.177853449259986	0.533560347779959	0.643853282854191	0.853049270252403
Crtam	ENSMUSG00000032021	0.0226344734406829	0.0679034203220487	0.343537039781257	0.515305559671886	0.926658283600152	0.926658283600152
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Icam5	ENSMUSG00000032174	0.71082910328023	0.78132892626786	0.78132892626786	0.78132892626786	0.578113371816017	0.78132892626786
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Kif9	ENSMUSG00000032489	0.853694531487825	0.853694531487825	0.853694531487825	0.853694531487825	0.144157978128026	0.432473934384077
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Fbxl21	ENSMUSG00000035509	0.0334587898203823	0.100376369461147	0.252920381501207	0.37938057225181	0.511097249598474	0.511097249598474
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
H2-DMb2	ENSMUSG00000037548	0.050156830152886	0.150470490458658	0.606113826568149	0.606113826568149	0.453225835454267	0.606113826568149
Mylip	ENSMUSG00000038175	0.71082910328023	0.71082910328023	0.287481513930451	0.71082910328023	0.640608766263372	0.71082910328023
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Klhl42	ENSMUSG00000040102	0.344288444541856	0.861125960300578	0.574083973533718	0.861125960300578	0.92589277149125	0.92589277149125
Cd79b	ENSMUSG00000040592	0.189061599254104	0.567184797762312	0.607438359373598	0.849805525376199	0.849805525376199	0.849805525376199
Sh3kbp1	ENSMUSG00000040990	0.443306001726868	0.568427079091759	0.568427079091759	0.568427079091759	0.501782052576058	0.568427079091759
H2-Ob	ENSMUSG00000041538	0.222938437045269	0.668815311135807	1	1	0.774176834800231	1
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Hecw2	ENSMUSG00000042807	0.696899768923163	0.696899768923163	0.0196307077218453	0.0588921231655358	0.0599532724680346	0.0899299087020519
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Treml4	ENSMUSG00000051682	0.398469281729516	0.640608766263372	0.640608766263372	0.640608766263372	0.574375606171923	0.640608766263372
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Ap1s3	ENSMUSG00000054702	0.400265374208515	0.769540304784424	1	1	0.513026869856283	0.769540304784424
Ifitm6	ENSMUSG00000059108	0.0367873939579746	0.110362181873924	0.57113445032749	0.856701675491234	0.9255572759333	0.9255572759333
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Ifitm2	ENSMUSG00000060591	0.29558111906036	0.708534948098331	0.633577343537212	0.708534948098331	0.708534948098331	0.708534948098331
Blnk	ENSMUSG00000061132	0.708534948098331	0.853694531487825	0.853694531487825	0.853694531487825	0.642366752097095	0.853694531487825
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Rasgrp3	ENSMUSG00000071042	0.35584851444916	0.43283647035887	0.43283647035887	0.43283647035887	0.288654423610209	0.43283647035887
Treml2	ENSMUSG00000071068	0.45713435082887	0.685701526243305	0.757262551816799	0.757262551816799	0.150680196006792	0.452040588020377
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667
Cd101	ENSMUSG00000086564	0.0331400397096515	0.0994201191289545	0.148115998140415	0.21549027811633	0.21549027811633	0.21549027811633

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Platelet activation, signaling and aggregation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Itih3	ENSMUSG00000006522	0.853694531487825	0.853694531487825	0.0331400397096515	0.0849569093781905	0.0566379395854603	0.0849569093781905
Srgn	ENSMUSG00000020077	0.384672302267076	0.577008453400614	0.84992097596507	0.84992097596507	0.342405296020881	0.577008453400614
Plek	ENSMUSG00000020120	0.611013261098418	0.916519891647627	1	1	0.00130806497567845	0.00392419492703534
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Prkch	ENSMUSG00000021108	0.0434033576198681	0.130210072859604	0.57113445032749	0.57113445032749	0.392985378348026	0.57113445032749
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Clu	ENSMUSG00000022037	0.279118898313835	0.710416009055326	0.486016534591995	0.710416009055326	0.710416009055326	0.710416009055326
Fam49b	ENSMUSG00000022378	0.490462404969451	1	0.849805525376199	1	1	1
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Fermt3	ENSMUSG00000024965	0.130037529335642	0.390112588006927	0.494796118234289	0.494796118234289	0.390750658104794	0.494796118234289
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Anxa5	ENSMUSG00000027712	0.334323804341914	0.852175490580835	0.7802108304765	0.852175490580835	0.852175490580835	0.852175490580835
A2m	ENSMUSG00000030111	0.652428537343768	0.652428537343768	0.652428537343768	0.652428537343768	0.3181679107269	0.652428537343768
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gna15	ENSMUSG00000034792	0.78180291566155	1	1	1	0.347639524025037	1
Tbxa2r	ENSMUSG00000034881	0.0426702157436794	0.128010647231038	0.211844580334808	0.317766870502212	0.514934023620344	0.514934023620344
P2ry12	ENSMUSG00000036353	0.449743164679353	0.67461474701903	0.853372965654504	0.853372965654504	0.0219958379984644	0.0659875139953931
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Ttn	ENSMUSG00000051747	0.428954561529433	0.846637195024074	0.564424796682716	0.846637195024074	0.91779257176357	0.91779257176357
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Tor4a	ENSMUSG00000059555	0.346899083932133	0.454942951775341	0.299349060054895	0.454942951775341	0.454942951775341	0.454942951775341
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Arrb2	ENSMUSG00000060216	1	1	0.5155648232968	0.7733472349452	0.17750354896016	0.53251064688048
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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Translocation of ZAP-70 to Immunological synapse

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342

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Integrin signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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Rap1 signalling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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DAP12 interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Clec5a	ENSMUSG00000029915	0.249907451332337	0.643853282854191	0.509144723230069	0.643853282854191	0.643853282854191	0.643853282854191
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
Siglecg	ENSMUSG00000030468	0.68129770017266	0.777922216623952	0.758766047369853	0.777922216623952	0.777922216623952	0.777922216623952
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667

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Cytokine Signaling in Immune system

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Il16	ENSMUSG00000001741	0.270898788519615	0.6275332346787	0.6275332346787	0.6275332346787	0.573791743469336	0.6275332346787
Ebi3	ENSMUSG00000003206	0.147458757705094	0.221188136557642	0.00768144932639892	0.0230443479791968	0.85117361048289	0.85117361048289
Il7r	ENSMUSG00000003882	0.335105706965705	0.560630351397847	0.560630351397847	0.560630351397847	0.397021051130447	0.560630351397847
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Il27ra	ENSMUSG00000005465	0.108244222162358	0.324732666487074	1	1	0.455625354715449	0.683438032073173
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Ager	ENSMUSG00000015452	0.400265374208515	0.600398061312773	0.853694531487825	0.853694531487825	0.400265374208515	0.600398061312773
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Sla	ENSMUSG00000022372	0.195291845935736	0.292937768903604	0.920461794456068	0.920461794456068	0.0434194723707709	0.130258417112313
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Tnfsf8	ENSMUSG00000028362	0.307838294631065	0.354081512249118	0.354081512249118	0.354081512249118	0.264135602004534	0.354081512249118
Cntfr	ENSMUSG00000028444	0.776750778128093	0.776750778128093	0.776750778128093	0.776750778128093	0.450444934184774	0.776750778128093
Tnfrsf8	ENSMUSG00000028602	0.253668577981715	0.253668577981715	0.176451829330851	0.253668577981715	0.00468160475316412	0.0140448142594924
Tnfrsf9	ENSMUSG00000028965	0.329576740674783	0.504410496659194	0.843929879174112	0.843929879174112	0.336273664439462	0.504410496659194
Cd27	ENSMUSG00000030336	0.328374849423202	0.642864324224729	0.615734841980377	0.642864324224729	0.642864324224729	0.642864324224729
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Dusp4	ENSMUSG00000031530	0.781011212316137	0.781011212316137	0.576687400573867	0.781011212316137	0.145811394942709	0.437434184828127
Il10ra	ENSMUSG00000032089	0.00677874009944962	0.0203362202983489	0.695465770969712	0.695465770969712	0.399189600887034	0.598784401330551
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Socs5	ENSMUSG00000037104	0.297095062262362	0.450143880930327	0.300095920620218	0.450143880930327	0.853049270252403	0.853049270252403
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Clcf1	ENSMUSG00000040663	0.769866760519794	0.769866760519794	0.566285712787375	0.769866760519794	0.300095920620218	0.769866760519794
Tnfrsf18	ENSMUSG00000041954	0.109793509122179	0.329380527366537	0.776919261684345	0.776919261684345	0.5155648232968	0.7733472349452
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Dusp7	ENSMUSG00000053716	0.45596561163947	0.683948417459205	1	1	0.298974794311434	0.683948417459205
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Osm	ENSMUSG00000058755	0.210374401237615	0.210374401237615	0.0164739112492867	0.0247108668739301	0.0160600007544847	0.0247108668739301
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972

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Interleukin-2 family signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Il9r	ENSMUSG00000020279	0.835361872536451	0.835361872536451	0.753490930300721	0.835361872536451	0.000995245646227929	0.00298573693868379
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Il21r	ENSMUSG00000030745	0.20056320244511	0.601689607335331	0.535589379512136	0.703333998861023	0.703333998861023	0.703333998861023
Pik3cd	ENSMUSG00000039936	0.0206143723118986	0.0565387936866606	0.924639851733043	0.924639851733043	0.0376925291244404	0.0565387936866606
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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CD28 dependent Vav1 pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Platelet Aggregation (Plug Formation)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709

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TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1

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Hemostasis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Vpreb3	ENSMUSG00000000903	0.222938437045269	0.435315022773717	0.838035561936097	0.838035561936097	0.290210015182478	0.435315022773717
Tgfb1	ENSMUSG00000002603	0.447621891168214	0.708534948098331	0.641867098978198	0.708534948098331	0.708534948098331	0.708534948098331
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Sh2b2	ENSMUSG00000005057	0.49228148038523	0.770019415933663	0.92350506192425	0.92350506192425	0.513346277289108	0.770019415933663
P2rx5	ENSMUSG00000005950	0.111957284180537	0.169324023937537	0.112882682625025	0.169324023937537	0.204049463366727	0.204049463366727
Itih3	ENSMUSG00000006522	0.853694531487825	0.853694531487825	0.0331400397096515	0.0849569093781905	0.0566379395854603	0.0849569093781905
Cd48	ENSMUSG00000015355	0.118409250205154	0.355227750615461	0.773651283337324	0.773651283337324	0.292141300005423	0.438211950008134
Srgn	ENSMUSG00000020077	0.384672302267076	0.577008453400614	0.84992097596507	0.84992097596507	0.342405296020881	0.577008453400614
Plek	ENSMUSG00000020120	0.611013261098418	0.916519891647627	1	1	0.00130806497567845	0.00392419492703534
Dock2	ENSMUSG00000020143	0.27871391172685	0.675141569480709	0.692783110017144	0.692783110017144	0.450094379653806	0.675141569480709
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Prkch	ENSMUSG00000021108	0.0434033576198681	0.130210072859604	0.57113445032749	0.57113445032749	0.392985378348026	0.57113445032749
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Clu	ENSMUSG00000022037	0.279118898313835	0.710416009055326	0.486016534591995	0.710416009055326	0.710416009055326	0.710416009055326
Dok2	ENSMUSG00000022102	0.78180291566155	0.926333123228344	0.926333123228344	0.926333123228344	0.295581119060361	0.886743357181082
Fam49b	ENSMUSG00000022378	0.490462404969451	1	0.849805525376199	1	1	1
Rapgef3	ENSMUSG00000022469	0.213672724643677	0.64101817393103	0.567513221841557	0.851269832762335	0.923011676492635	0.923011676492635
Ehd3	ENSMUSG00000024065	0.0434194723707708	0.130258417112313	0.513026869856283	0.769540304784424	0.78180291566155	0.78180291566155
Fermt3	ENSMUSG00000024965	0.130037529335642	0.390112588006927	0.494796118234289	0.494796118234289	0.390750658104794	0.494796118234289
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Fcamr	ENSMUSG00000026415	0.915419214029334	0.915419214029334	0.529423545289923	0.915419214029334	0.765885897846303	0.915419214029334
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Apbb1ip	ENSMUSG00000026786	0.424993524493889	0.922317414627388	0.922317414627388	0.922317414627388	0.701310685803632	0.922317414627388
Rasgrp1	ENSMUSG00000027347	0.101081106532696	0.303243319598088	1	1	0.575536202757516	0.863304304136274
Anxa5	ENSMUSG00000027712	0.334323804341914	0.852175490580835	0.7802108304765	0.852175490580835	0.852175490580835	0.852175490580835
Slc7a11	ENSMUSG00000027737	0.919624777448804	0.919624777448804	0.119713811475365	0.265729968351089	0.177153312234059	0.265729968351089
A2m	ENSMUSG00000030111	0.652428537343768	0.652428537343768	0.652428537343768	0.652428537343768	0.3181679107269	0.652428537343768
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Dock11	ENSMUSG00000031093	0.235939938845945	0.353909908268917	0.162867964743396	0.353909908268917	1	1
F9	ENSMUSG00000031138	0.843145898603248	0.843145898603248	0.556735553349253	0.835103330023879	0.160678859790996	0.482036579372987
Jam3	ENSMUSG00000031990	0.5155648232968	0.7733472349452	0.348008842235184	0.7733472349452	0.78180291566155	0.78180291566155
Gnb5	ENSMUSG00000032192	0.853801250889739	0.926658283600152	0.711854160331342	0.926658283600152	0.926658283600152	0.926658283600152
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Kif9	ENSMUSG00000032489	0.853694531487825	0.853694531487825	0.853694531487825	0.853694531487825	0.144157978128026	0.432473934384077
Rasgrp2	ENSMUSG00000032946	0.57113445032749	0.577829325134931	0.447621891168214	0.577829325134931	0.577829325134931	0.577829325134931
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Gna15	ENSMUSG00000034792	0.78180291566155	1	1	1	0.347639524025037	1
Tbxa2r	ENSMUSG00000034881	0.0426702157436794	0.128010647231038	0.211844580334808	0.317766870502212	0.514934023620344	0.514934023620344
P2ry12	ENSMUSG00000036353	0.449743164679353	0.67461474701903	0.853372965654504	0.853372965654504	0.0219958379984644	0.0659875139953931
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Gng10	ENSMUSG00000038607	0.391871008462511	0.587806512693766	0.24838880320704	0.587806512693766	0.777755996383525	0.777755996383525
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Gng2	ENSMUSG00000043004	0.0592616003460512	0.17761387530773	0.514934023620345	0.514934023620345	0.118409250205154	0.17761387530773
Epcam	ENSMUSG00000045394	0.78180291566155	0.782117202022501	0.782117202022501	0.782117202022501	0.015650433288145	0.0469512998644349
Plaur	ENSMUSG00000046223	0.17750354896016	0.256271555563966	0.256271555563966	0.256271555563966	0.148115998140416	0.256271555563966
Rapgef4	ENSMUSG00000049044	0.486765503970733	0.730148255956099	0.921669692601187	0.921669692601187	0.45596561163947	0.730148255956099
Spn	ENSMUSG00000051457	0.109793509122179	0.31112022882692	0.710416009055326	0.710416009055326	0.207413485884614	0.31112022882692
Ttn	ENSMUSG00000051747	0.428954561529433	0.846637195024074	0.564424796682716	0.846637195024074	0.91779257176357	0.91779257176357
Dock8	ENSMUSG00000052085	0.450094379653806	0.511097249598474	0.511097249598474	0.511097249598474	0.255901190956604	0.511097249598474
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Tor4a	ENSMUSG00000059555	0.346899083932133	0.454942951775341	0.299349060054895	0.454942951775341	0.454942951775341	0.454942951775341
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Arrb2	ENSMUSG00000060216	1	1	0.5155648232968	0.7733472349452	0.17750354896016	0.53251064688048
Prcp	ENSMUSG00000061119	0.167929015438905	0.503787046316716	0.778253541606068	0.778253541606068	0.346527959006435	0.519791938509652
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062

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DAP12 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Klrc1	ENSMUSG00000030167	0.392985378348026	0.392985378348026	0.195291845935736	0.300975329422321	0.200650219614881	0.300975329422321
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Btk	ENSMUSG00000031264	0.606777760525367	0.606777760525367	0.606113826568149	0.606777760525367	0.118323633568665	0.354970900705996
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667

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CD28 co-stimulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Cd86	ENSMUSG00000022901	0.113498953177704	0.340496859533111	0.639337105615665	0.711650020253571	0.711650020253571	0.711650020253571
Map3k8	ENSMUSG00000024235	0.5155648232968	0.5155648232968	0.5155648232968	0.5155648232968	0.514934023620344	0.5155648232968
Cd28	ENSMUSG00000026012	0.181112542971101	0.361593540405014	0.241062360270009	0.361593540405014	0.567513221841557	0.567513221841557
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Cd80	ENSMUSG00000075122	0.51077343128446	0.708323672944427	0.708323672944427	0.708323672944427	0.173278494483978	0.519835483451934

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Downstream TCR signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Pten	ENSMUSG00000013663	0.11810342389482	0.354310271684459	0.567818482366294	0.567818482366294	0.246861959455465	0.370292939183197
Inpp5d	ENSMUSG00000026288	0.545469883829987	0.818204825744981	1	1	0.00943994294581104	0.0283198288374331
Prkcq	ENSMUSG00000026778	0.297848640636702	0.517556086579331	0.710001140920767	0.710001140920767	0.345037391052887	0.517556086579331
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Malt1	ENSMUSG00000032688	0.241062360270009	0.361593540405014	0.0217422311863571	0.0652266935590714	0.708745765211584	0.708745765211584
Card11	ENSMUSG00000036526	0.208897379073412	0.382180685423407	0.850151080737202	0.850151080737202	0.254787123615605	0.382180685423407
H2-Eb2	ENSMUSG00000067341	0.469500032898643	0.924286968561133	0.68129770017266	0.924286968561133	0.924286968561133	0.924286968561133
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972

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FLT3 Signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Sla	ENSMUSG00000022372	0.195291845935736	0.292937768903604	0.920461794456068	0.920461794456068	0.0434194723707709	0.130258417112313
Csk	ENSMUSG00000032312	0.299349060054895	0.596076093399921	0.397384062266614	0.596076093399921	0.706831781264721	0.706831781264721
Grap2	ENSMUSG00000042351	0.301189778427735	0.379206615039809	0.356726814244713	0.379206615039809	0.379206615039809	0.379206615039809
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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GPVI-mediated activation cascade

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Lcp2	ENSMUSG00000002699	0.452880492349546	0.679320738524319	0.78180291566155	0.78180291566155	0.347639524025037	0.679320738524319
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Pik3cg	ENSMUSG00000020573	0.635703516568383	0.635703516568383	0.246478961478169	0.369718442217254	0.00153425095635555	0.00460275286906665
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Lat	ENSMUSG00000030742	0.102330841428063	0.30699252428419	0.376820650682115	0.565230976023172	0.641867098978198	0.641867098978198
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Plcg2	ENSMUSG00000034330	0.636229315311352	0.636229315311352	0.295581119060361	0.636229315311352	0.496922356453102	0.636229315311352

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TNFs bind their physiological receptors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Tnfsf8	ENSMUSG00000028362	0.307838294631065	0.354081512249118	0.354081512249118	0.354081512249118	0.264135602004534	0.354081512249118
Tnfrsf8	ENSMUSG00000028602	0.253668577981715	0.253668577981715	0.176451829330851	0.253668577981715	0.00468160475316412	0.0140448142594924
Tnfrsf9	ENSMUSG00000028965	0.329576740674783	0.504410496659194	0.843929879174112	0.843929879174112	0.336273664439462	0.504410496659194
Cd27	ENSMUSG00000030336	0.328374849423202	0.642864324224729	0.615734841980377	0.642864324224729	0.642864324224729	0.642864324224729
Tnfrsf18	ENSMUSG00000041954	0.109793509122179	0.329380527366537	0.776919261684345	0.776919261684345	0.5155648232968	0.7733472349452

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TNFR2 non-canonical NF-kB pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tnfsf14	ENSMUSG00000005824	0.0236697127745139	0.0710091383235417	0.346527959006434	0.519791938509652	0.853694531487825	0.853694531487825
Tnfrsf13b	ENSMUSG00000010142	0.562223318517824	0.562223318517824	0.287481513930451	0.431222270895677	0.13849172243875	0.415475167316251
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Traf3	ENSMUSG00000021277	0.925613508363027	0.925613508363027	0.925613508363027	0.925613508363027	0.179597906187076	0.538793718561229
Ltb	ENSMUSG00000024399	0.192968864514283	0.578906593542849	0.843408536616192	0.843408536616192	0.782117202022501	0.843408536616192
Tnf	ENSMUSG00000024401	0.072378961026407	0.217136883079221	0.297095062262362	0.297095062262362	0.21549027811633	0.297095062262362
Lta	ENSMUSG00000024402	0.340840580471473	0.51126087070721	0.294820734456232	0.51126087070721	0.926278508226733	0.926278508226733
Nfkb2	ENSMUSG00000025225	0.453225835454266	0.679838753181399	0.711240436189781	0.711240436189781	0.450444934184774	0.679838753181399
Tnfsf8	ENSMUSG00000028362	0.307838294631065	0.354081512249118	0.354081512249118	0.354081512249118	0.264135602004534	0.354081512249118
Tnfrsf8	ENSMUSG00000028602	0.253668577981715	0.253668577981715	0.176451829330851	0.253668577981715	0.00468160475316412	0.0140448142594924
Tnfrsf9	ENSMUSG00000028965	0.329576740674783	0.504410496659194	0.843929879174112	0.843929879174112	0.336273664439462	0.504410496659194
Cd27	ENSMUSG00000030336	0.328374849423202	0.642864324224729	0.615734841980377	0.642864324224729	0.642864324224729	0.642864324224729
Tnfrsf18	ENSMUSG00000041954	0.109793509122179	0.329380527366537	0.776919261684345	0.776919261684345	0.5155648232968	0.7733472349452
Birc2	ENSMUSG00000057367	0.711240436189781	0.926333123228344	0.926333123228344	0.926333123228344	0.346527959006435	0.926333123228344
Tnfrsf13c	ENSMUSG00000068105	0.606113826568149	1	1	1	0.766467256503162	1
Psme2b	ENSMUSG00000078153	0.925444427431699	0.925444427431699	0.710001140920767	0.925444427431699	0.250285839267991	0.750857517803972

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Cross-presentation of particulate exogenous antigens (phagosomes)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Icam2	ENSMUSG00000001029	0.119631084167592	0.358893252502775	0.568427079091759	0.568427079091759	0.297848640636702	0.446772960955053
Itgb7	ENSMUSG00000001281	0.0199974585097312	0.0599923755291937	0.438516479093275	0.57466664340579	0.57466664340579	0.57466664340579
Cd3g	ENSMUSG00000002033	0.0953125666339397	0.285937699901819	0.25141795904251	0.346899083932133	0.346899083932133	0.346899083932133
Cd247	ENSMUSG00000005763	0.157372722062346	0.472118166187038	0.364479238287877	0.546718857431816	0.563485358844814	0.563485358844814
Slamf6	ENSMUSG00000015314	0.458890710010385	0.603084091822085	0.603084091822085	0.603084091822085	0.117975613258695	0.353926839776085
Cd40	ENSMUSG00000017652	0.559988304776178	0.57113445032749	0.57113445032749	0.57113445032749	0.180293335960318	0.540880007880955
Cd96	ENSMUSG00000022657	0.113498953177704	0.340496859533111	0.291756209988535	0.437634314982803	0.452880492349546	0.452880492349546
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Vcam1	ENSMUSG00000027962	0.145022556567793	0.43506766970338	1	1	0.852395395941406	1
Klrk1	ENSMUSG00000030149	0.712057867818062	0.78180291566155	0.78180291566155	0.78180291566155	0.113190884633071	0.339572653899213
Siglecg	ENSMUSG00000030468	0.68129770017266	0.777922216623952	0.758766047369853	0.777922216623952	0.777922216623952	0.777922216623952
Cd19	ENSMUSG00000030724	0.302533785918098	0.575536202757516	0.40611577256979	0.575536202757516	0.575536202757516	0.575536202757516
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Crtam	ENSMUSG00000032021	0.0226344734406829	0.0679034203220487	0.343537039781257	0.515305559671886	0.926658283600152	0.926658283600152
Cd3e	ENSMUSG00000032093	0.195291845935736	0.585875537807208	0.569937449249116	0.854906173873675	0.9255572759333	0.9255572759333
Cd3d	ENSMUSG00000032094	0.0164739112492867	0.0494217337478602	1	1	0.643359829732651	0.965039744598977
Icam5	ENSMUSG00000032174	0.71082910328023	0.78132892626786	0.78132892626786	0.78132892626786	0.578113371816017	0.78132892626786
Treml4	ENSMUSG00000051682	0.398469281729516	0.640608766263372	0.640608766263372	0.640608766263372	0.574375606171923	0.640608766263372
Cd8b1	ENSMUSG00000053044	0.177070366725498	0.26327819155408	0.101081106532696	0.26327819155408	0.26327819155408	0.26327819155408
Ifitm6	ENSMUSG00000059108	0.0367873939579746	0.110362181873924	0.57113445032749	0.856701675491234	0.9255572759333	0.9255572759333
Ifitm2	ENSMUSG00000060591	0.29558111906036	0.708534948098331	0.633577343537212	0.708534948098331	0.708534948098331	0.708534948098331
Treml2	ENSMUSG00000071068	0.45713435082887	0.685701526243305	0.757262551816799	0.757262551816799	0.150680196006792	0.452040588020377
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Trbc1	ENSMUSG00000076490	0.206668954082487	0.373153847131552	0.706831781264722	0.706831781264722	0.248769231421035	0.373153847131552
Trbc2	ENSMUSG00000076498	0.0206143723118986	0.0618431169356959	0.68129770017266	0.68129770017266	0.345037391052887	0.51755608657933
Trac	ENSMUSG00000076928	0.395928178642446	0.711854160331342	0.514934023620345	0.711854160331342	0.711854160331342	0.711854160331342
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667

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RHO GTPases Activate NADPH Oxidases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Rac2	ENSMUSG00000033220	0.231130630776632	0.231130630776632	0.142498552923913	0.21374782938587	0.0320312337221707	0.096093701166512
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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Chondroitin sulfate biosynthesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Chst15	ENSMUSG00000030930	0.298974794311434	0.640101714462795	0.45596561163947	0.640101714462795	0.640101714462795	0.640101714462795
Chsy1	ENSMUSG00000032640	0.21494612068098	0.644838362042941	0.690028363829288	1	1	1
Chst11	ENSMUSG00000034612	0.0953125666339396	0.252969978550618	0.850721744111585	0.850721744111585	0.168646652367079	0.252969978550618
Csgalnact2	ENSMUSG00000042042	0.926550375688041	0.926550375688041	0.712057867818062	0.926550375688041	0.0579478375430677	0.173843512629203
Chst9	ENSMUSG00000047161	0.395928178642446	0.395928178642446	0.172569605656602	0.395928178642446	0.296339225025931	0.395928178642446
Chst3	ENSMUSG00000057337	0.755951227598167	1	0.836715131145005	1	1	1

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Interleukin-2 signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Syk	ENSMUSG00000021457	0.511742979522636	0.513665062682276	0.288654423610209	0.513665062682276	0.513665062682276	0.513665062682276
Il2ra	ENSMUSG00000026770	0.205174703261494	0.29252580908486	0.288654423610209	0.29252580908486	0.29252580908486	0.29252580908486
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904

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Lysosphingolipid and LPA receptors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
S1pr2	ENSMUSG00000043895	0.0241933715424143	0.0725801146272429	0.852504981253341	0.852504981253341	0.513026869856283	0.769540304784424
S1pr4	ENSMUSG00000044199	0.178287767933578	0.534863303800733	0.424592967853335	0.636889451780002	0.781011212316137	0.781011212316137
S1pr1	ENSMUSG00000045092	0.628654363853655	0.628654363853655	0.384672302267076	0.577008453400614	0.293293089483362	0.577008453400614
S1pr3	ENSMUSG00000067586	0.00731348855817121	0.0219404656745136	0.392243127063687	0.505169133438821	0.505169133438821	0.505169133438821

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DSCAM interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Dscaml1	ENSMUSG00000032087	0.841541831004442	0.91801907193707	0.91801907193707	0.91801907193707	0.529816072081339	0.91801907193707
Dscam	ENSMUSG00000050272	0.562223318517824	0.697136806831382	0.697136806831382	0.697136806831382	0.688236318022	0.697136806831382
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1

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Regulation of KIT signaling

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lck	ENSMUSG00000000409	0.140165358447409	0.420496075342227	0.780851835278818	0.780851835278818	0.641867098978198	0.780851835278818
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Sh2b2	ENSMUSG00000005057	0.49228148038523	0.770019415933663	0.92350506192425	0.92350506192425	0.513346277289108	0.770019415933663
Sh2b3	ENSMUSG00000042594	0.774176834800231	0.84934104438081	0.84934104438081	0.84934104438081	0.780851835278818	0.84934104438081
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463

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Signal regulatory protein family interactions

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fyb	ENSMUSG00000022148	0.398108175780842	0.597162263671263	1	1	0.177853449259986	0.533560347779958
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Grb2	ENSMUSG00000059923	0.254414773803597	0.763244321410791	0.638310022345193	0.924872384323463	0.924872384323463	0.924872384323463
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062

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VEGFA-VEGFR2 Pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Prkacb	ENSMUSG00000005034	0.573791743469336	0.573791743469336	0.393724994268831	0.573791743469336	0.388491809581663	0.573791743469336
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Ncf1	ENSMUSG00000015950	0.841812594759375	0.845463210524231	0.845463210524231	0.845463210524231	0.175044824745981	0.525134474237942
Akt3	ENSMUSG00000019699	0.704440461749122	0.706616781330066	0.705968934865368	0.706616781330066	0.706616781330066	0.706616781330066
Cyfip2	ENSMUSG00000020340	0.605446529449261	0.921139684946258	0.764115430291227	0.921139684946258	0.921139684946258	0.921139684946258
Nckap1l	ENSMUSG00000022488	0.0548979200435555	0.0823468800653333	1	1	0.0110666956860337	0.0332000870581011
Mapk12	ENSMUSG00000022610	0.180293335960318	0.540880007880955	0.397384062266614	0.596076093399921	0.641867098978198	0.641867098978198
Ncf2	ENSMUSG00000026480	0.0321889748775514	0.0482834623163272	0.348008842235184	0.348008842235184	0.00481536616919077	0.0144460985075723
Sh2d2a	ENSMUSG00000028071	0.0886202385494146	0.132930357824122	0.486765503970733	0.486765503970733	0.0535981760208404	0.132930357824122
Vav1	ENSMUSG00000034116	0.491192352323595	0.491192352323595	0.295581119060361	0.443371678590541	0.024062085667391	0.072186257002173
Elmo1	ENSMUSG00000041112	0.179945789077372	0.51755608657933	0.926550375688041	0.926550375688041	0.345037391052887	0.51755608657933
Prkcb	ENSMUSG00000052889	0.467843823235957	0.83686344227219	0.83686344227219	0.83686344227219	0.776919261684345	0.83686344227219
Mapk11	ENSMUSG00000053137	0.319786844594194	0.959360533782583	0.842349984490669	1	1	1
Ptk2b	ENSMUSG00000059456	0.573498913947369	0.77858338846904	0.77858338846904	0.77858338846904	0.634645058916812	0.77858338846904
Ncf4	ENSMUSG00000071715	0.41848462695615	0.772410589885492	0.772410589885492	0.772410589885492	0.704440461749122	0.772410589885492

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Neutrophil degranulation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cfp	ENSMUSG00000001128	0.0331400397096515	0.0994201191289544	0.7802108304765	0.7802108304765	0.0746183450292888	0.111927517543933
Ap1m1	ENSMUSG00000003033	1	1	1	1	0.0753654386865989	0.226096316059797
Slc2a3	ENSMUSG00000003153	0.148115998140416	0.444347994421247	0.578113371816017	0.578113371816017	0.514934023620345	0.578113371816017
Hmox2	ENSMUSG00000004070	0.78148726569172	0.926658283600152	0.926658283600152	0.926658283600152	0.853694531487825	0.926658283600152
Ptpn6	ENSMUSG00000004266	0.923321156062851	0.923321156062851	0.505838378028518	0.758757567042777	0.295581119060361	0.758757567042777
Cnn2	ENSMUSG00000004665	0.269223850346639	0.443306001726868	0.443306001726868	0.443306001726868	0.43283647035887	0.443306001726868
Abca13	ENSMUSG00000004668	0.39335551479284	0.51270683838022	0.247244441753849	0.51270683838022	0.51270683838022	0.51270683838022
Trpm2	ENSMUSG00000009292	0.0880615565264046	0.132092334789607	0.7802108304765	0.7802108304765	0.0763619660358787	0.132092334789607
1810033B17Rik	ENSMUSG00000013974	0.123175587755902	0.255438305988142	0.255438305988142	0.255438305988142	0.189061599254104	0.255438305988142
Cybb	ENSMUSG00000015340	0.0936419271039908	0.140462890655986	0.847921313356738	0.847921313356738	0.0241933715424143	0.0725801146272428
Dock2	ENSMUSG00000020143	0.27871391172685	0.675141569480709	0.692783110017144	0.692783110017144	0.450094379653806	0.675141569480709
Pecam1	ENSMUSG00000020717	0.211844580334808	0.514934023620345	0.514934023620345	0.514934023620345	0.346527959006435	0.514934023620345
Lpcat1	ENSMUSG00000021608	0.144820068500793	0.21723010275119	0.246861959455465	0.246861959455465	0.0548979200435556	0.164693760130667
Nckap1l	ENSMUSG00000022488	0.0548979200435555	0.0823468800653333	1	1	0.0110666956860337	0.0332000870581011
C3	ENSMUSG00000024164	0.575824878403157	0.575824878403157	0.398108175780842	0.575824878403157	0.17433930265919	0.523017907977569
Adam8	ENSMUSG00000025473	0.179945789077372	0.269918683616058	0.712057867818062	0.712057867818062	0.0753654386865988	0.226096316059796
Ptprc	ENSMUSG00000026395	0.489729342752048	0.734594014128071	1	1	0.091411676944639	0.274235030833917
Fcna	ENSMUSG00000026938	0.926658283600152	0.926658283600152	0.514934023620345	0.772401035430517	0.299349060054895	0.772401035430517
Fabp5	ENSMUSG00000027533	0.378414240914692	0.450794830295118	0.388491809581663	0.450794830295118	0.450794830295118	0.450794830295118
Nfkb1	ENSMUSG00000028163	0.254787123615605	0.382180685423408	0.578113371816017	0.578113371816017	0.211110344399808	0.382180685423408
Padi2	ENSMUSG00000028927	0.845337155620795	0.845337155620795	0.497625221907634	0.746437832861452	0.0232795908282423	0.0698387724847269
Kcnab2	ENSMUSG00000028931	0.329176790045262	0.493765185067894	0.707899741868332	0.707899741868332	0.297848640636703	0.493765185067894
Rhof	ENSMUSG00000029449	0.0964252305385474	0.144637845807821	0.643853282854191	0.643853282854191	0.0958690133561599	0.144637845807821
Clec5a	ENSMUSG00000029915	0.249907451332337	0.643853282854191	0.509144723230069	0.643853282854191	0.643853282854191	0.643853282854191
Clec4d	ENSMUSG00000030144	0.444032220827359	0.666048331241038	0.775389027507362	0.775389027507362	0.246095446958788	0.666048331241038
Lilra6	ENSMUSG00000030427	0.168646652367078	0.252969978550618	0.437393870295853	0.437393870295853	0.000333936947699979	0.00100181084309994
Itgal	ENSMUSG00000030830	0.269223850346639	0.403835775519958	0.922189155665787	0.922189155665787	0.0443599545252853	0.133079863575856
Hmha1	ENSMUSG00000035697	0.1540397616999	0.462119285099701	0.920735042422376	0.920735042422376	0.454942951775341	0.682414427663012
Dok3	ENSMUSG00000035711	0.610047953449801	0.610047953449801	0.542246307846122	0.610047953449801	0.395928178642446	0.610047953449801
Sirpa	ENSMUSG00000037902	0.211844580334808	0.317766870502212	0.180293335960318	0.317766870502212	0.710001140920767	0.710001140920767
Tbc1d10c	ENSMUSG00000040247	0.187486171644953	0.449023590082343	0.762100360299702	0.762100360299702	0.299349060054895	0.449023590082343
Arhgap9	ENSMUSG00000040345	0.0109864933352154	0.0329594800056461	0.6275332346787	0.78180291566155	0.78180291566155	0.78180291566155
Cd53	ENSMUSG00000040747	0.119713811475365	0.179570717213048	0.91861403840811	0.91861403840811	0.0746183450292887	0.179570717213048
Plaur	ENSMUSG00000046223	0.17750354896016	0.256271555563966	0.256271555563966	0.256271555563966	0.148115998140416	0.256271555563966
Plekho2	ENSMUSG00000050721	0.0928059258606269	0.278417777581881	0.924814453025535	0.924814453025535	0.332752104054419	0.499128156081629
Rap1b	ENSMUSG00000052681	0.447265995733381	0.670898993600072	0.852065168704833	0.852065168704833	0.399548817627028	0.670898993600072
Tnfaip6	ENSMUSG00000053475	0.169362944517671	0.508088833553014	0.641867098978197	0.641867098978197	0.398108175780842	0.597162263671263
Ticam2	ENSMUSG00000056130	0.00253244992826164	0.00759734978478491	0.0269590270291414	0.0404385405437121	0.250285839267991	0.250285839267991
Glipr1	ENSMUSG00000056888	1	1	0.575536202757516	0.863304304136274	0.214037080764326	0.642111242292977
Slc44a2	ENSMUSG00000057193	0.0637129576330108	0.191138872899032	0.479905817228256	0.479905817228256	0.241062360270009	0.361593540405014
Unc13d	ENSMUSG00000057948	0.781170242226513	0.781170242226513	0.25141795904251	0.754253877127531	0.514300775319626	0.771451162979439
Atp8b4	ENSMUSG00000060131	0.091132699670031	0.136699049505046	0.574375606171923	0.574375606171923	0.0758636487647837	0.136699049505046
Gmfg	ENSMUSG00000060791	0.777255087907932	0.924872384323463	0.924872384323463	0.924872384323463	0.338976281569376	0.924872384323463
Prcp	ENSMUSG00000061119	0.167929015438905	0.503787046316716	0.778253541606068	0.778253541606068	0.346527959006435	0.519791938509652
Chi3l1	ENSMUSG00000064246	0.45596561163947	0.45596561163947	0.252545530864481	0.450143880930327	0.300095920620218	0.450143880930327
Hvcn1	ENSMUSG00000064267	0.1811125429711	0.431809617602084	0.689264132039392	0.689264132039392	0.287873078401389	0.431809617602084
Rap1a	ENSMUSG00000068798	0.395928178642446	0.675141569480709	0.926441990075769	0.926441990075769	0.450094379653806	0.675141569480709
Lyz2	ENSMUSG00000069516	0.0328221470541517	0.098466441162455	0.6978446011211	0.707899741868332	0.707899741868332	0.707899741868332
H2-Q6	ENSMUSG00000073409	0.0109864933352154	0.0329594800056461	1	1	0.643359829732651	0.965039744598976
Gm14548	ENSMUSG00000074417	0.686149754455511	0.686149754455511	0.247825081352574	0.371737622028861	0.00814448596985833	0.024433457909575
Sirpb1c	ENSMUSG00000074677	0.0436072256433733	0.13082167693012	0.399548817627028	0.599323226440542	0.712057867818062	0.712057867818062
H2-T10	ENSMUSG00000079491	0.0108268982515582	0.0324806947546745	0.704660273783604	0.704660273783604	0.214401013708444	0.321601520562667
Pira2	ENSMUSG00000089942	0.553410011703054	0.553410011703054	0.388491809581663	0.553410011703054	0.511742979522636	0.553410011703054

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rosybrown4

Oxidative phosphorylation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Atp6v1g2	ENSMUSG00000024403	0.252545530864481	0.381622160705395	0.254414773803597	0.381622160705395	0.641867098978198	0.641867098978198
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Huntington disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sp1	ENSMUSG00000001280	0.392985378348026	0.392985378348026	0.000373355180054072	0.00112006554016222	0.120850531362929	0.181275797044394
Cacna1b	ENSMUSG00000004113	0.7802108304765	0.852832278580641	0.177153312234059	0.531459936702178	0.852832278580641	0.852832278580641
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Sod1	ENSMUSG00000022982	0.711240436189781	0.853801250889739	0.0523032931247597	0.156909879374279	0.853801250889739	0.853801250889739
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
Gpx1	ENSMUSG00000063856	0.216214347033995	0.324321520550992	0.0103546374915853	0.0310639124747558	0.776243028387552	0.776243028387552
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Diabetic cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sp1	ENSMUSG00000001280	0.392985378348026	0.392985378348026	0.000373355180054072	0.00112006554016222	0.120850531362929	0.181275797044394
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Gfpt1	ENSMUSG00000029992	0.148115998140416	0.222173997210623	0.000795094181770699	0.0023852825453121	0.639337105615665	0.639337105615665
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Non-alcoholic fatty liver disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Prkab1	ENSMUSG00000029513	0.388491809581663	0.505169133438821	0.0117179415987427	0.0351538247962282	0.505169133438821	0.505169133438821
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Cardiac muscle contraction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cacnb2	ENSMUSG00000057914	0.298599969973533	0.509798138101151	0.509798138101151	0.509798138101151	0.452880492349546	0.509798138101151
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Prion disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Cacna1b	ENSMUSG00000004113	0.7802108304765	0.852832278580641	0.177153312234059	0.531459936702178	0.852832278580641	0.852832278580641
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Sod1	ENSMUSG00000022982	0.711240436189781	0.853801250889739	0.0523032931247597	0.156909879374279	0.853801250889739	0.853801250889739
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Amyotrophic lateral sclerosis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Sod1	ENSMUSG00000022982	0.711240436189781	0.853801250889739	0.0523032931247597	0.156909879374279	0.853801250889739	0.853801250889739
Atf6	ENSMUSG00000026663	0.703556284613037	0.852065168704833	0.242231702094921	0.726695106284763	0.852065168704833	0.852065168704833
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
Gpx1	ENSMUSG00000063856	0.216214347033995	0.324321520550992	0.0103546374915853	0.0310639124747558	0.776243028387552	0.776243028387552
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Alzheimer disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Ncstn	ENSMUSG00000003458	0.709375484777034	0.709375484777034	0.140833168780851	0.422499506342554	0.575536202757516	0.709375484777034
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Atf6	ENSMUSG00000026663	0.703556284613037	0.852065168704833	0.242231702094921	0.726695106284763	0.852065168704833	0.852065168704833
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Adam10	ENSMUSG00000054693	0.852065168704833	0.852065168704833	0.0419238354397912	0.125771506319374	0.398829756175299	0.598244634262948
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Thermogenesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Prkab1	ENSMUSG00000029513	0.388491809581663	0.505169133438821	0.0117179415987427	0.0351538247962282	0.505169133438821	0.505169133438821
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Pathways of neurodegeneration - multiple diseases

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Cacna1b	ENSMUSG00000004113	0.7802108304765	0.852832278580641	0.177153312234059	0.531459936702178	0.852832278580641	0.852832278580641
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Sod1	ENSMUSG00000022982	0.711240436189781	0.853801250889739	0.0523032931247597	0.156909879374279	0.853801250889739	0.853801250889739
Atf6	ENSMUSG00000026663	0.703556284613037	0.852065168704833	0.242231702094921	0.726695106284763	0.852065168704833	0.852065168704833
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
Gpx1	ENSMUSG00000063856	0.216214347033995	0.324321520550992	0.0103546374915853	0.0310639124747558	0.776243028387552	0.776243028387552
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Adherens junction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Igf1r	ENSMUSG00000005533	0.399548817627028	0.643359829732651	0.454600801949285	0.643359829732651	0.643359829732651	0.643359829732651
Sorbs1	ENSMUSG00000025006	1	1	0.119631084167592	0.358893252502775	1	1
Ptprj	ENSMUSG00000025314	0.578113371816017	0.710416009055326	0.0206143723118986	0.0618431169356959	0.710416009055326	0.710416009055326
Tjp1	ENSMUSG00000030516	0.392985378348026	0.589478067522039	0.0544641512383264	0.163392453714979	0.643359829732651	0.643359829732651

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Parkinson disease

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sdhd	ENSMUSG00000000171	0.243396309647536	0.293293089483362	0.0103546374915853	0.0310639124747558	0.293293089483362	0.293293089483362
Sdhb	ENSMUSG00000009863	0.329176790045262	0.493765185067894	0.00885267753477384	0.0265580326043215	0.846952221585103	0.846952221585103
Atf6	ENSMUSG00000026663	0.703556284613037	0.852065168704833	0.242231702094921	0.726695106284763	0.852065168704833	0.852065168704833
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
Cox5b	ENSMUSG00000061518	0.711854160331342	0.711854160331342	0.0156504332881449	0.0469512998644348	0.398108175780842	0.597162263671263
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825
Cox7a1	ENSMUSG00000074218	0.926658283600152	0.926658283600152	0.0104326641569828	0.0312979924709483	0.926658283600152	0.926658283600152

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Synaptic vesicle cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cacna1b	ENSMUSG00000004113	0.7802108304765	0.852832278580641	0.177153312234059	0.531459936702178	0.852832278580641	0.852832278580641
Atp6v1g2	ENSMUSG00000024403	0.252545530864481	0.381622160705395	0.254414773803597	0.381622160705395	0.641867098978198	0.641867098978198
Dnm2	ENSMUSG00000033335	0.344663224299303	0.514934023620344	0.0241933715424143	0.0725801146272429	0.514934023620344	0.514934023620344
Cacna1a	ENSMUSG00000034656	0.177153312234059	0.531459936702178	0.643112334413352	0.926496242814507	0.926496242814507	0.926496242814507

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Hypertrophic cardiomyopathy

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Itgb4	ENSMUSG00000020758	0.400265374208515	0.600398061312773	0.253294730253595	0.600398061312773	0.926658283600152	0.926658283600152
Itga6	ENSMUSG00000027111	0.782117202022501	0.782117202022501	0.00486041086018214	0.0145812325805464	0.252920381501207	0.37938057225181
Prkab1	ENSMUSG00000029513	0.388491809581663	0.505169133438821	0.0117179415987427	0.0351538247962282	0.505169133438821	0.505169133438821
Cacnb2	ENSMUSG00000057914	0.298599969973533	0.509798138101151	0.509798138101151	0.509798138101151	0.452880492349546	0.509798138101151

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Presynaptic depolarization and calcium channel opening

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cacna1b	ENSMUSG00000004113	0.7802108304765	0.852832278580641	0.177153312234059	0.531459936702178	0.852832278580641	0.852832278580641
Cacna1a	ENSMUSG00000034656	0.177153312234059	0.531459936702178	0.643112334413352	0.926496242814507	0.926496242814507	0.926496242814507
Cacnb2	ENSMUSG00000057914	0.298599969973533	0.509798138101151	0.509798138101151	0.509798138101151	0.452880492349546	0.509798138101151

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TP53 Regulates Metabolic Genes

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Lamtor2	ENSMUSG00000028062	0.711854160331342	0.711854160331342	0.00450646370870541	0.0135193911261162	0.213307944885796	0.319961917328694
Prdx1	ENSMUSG00000028691	0.447265995733381	0.670898993600072	0.00675327520987522	0.0202598256296257	0.704220158648919	0.704220158648919
Prkab1	ENSMUSG00000029513	0.388491809581663	0.505169133438821	0.0117179415987427	0.0351538247962282	0.505169133438821	0.505169133438821
Cox8a	ENSMUSG00000035885	0.0958690133561599	0.11595859961889	0.0741204440774082	0.11595859961889	0.11595859961889	0.11595859961889
mt-Co3	ENSMUSG00000064358	0.577829325134931	0.853694531487825	0.577259514257969	0.853694531487825	0.853694531487825	0.853694531487825

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Synthesis of 15-eicosatetraenoic acid derivatives

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gpx1	ENSMUSG00000063856	0.216214347033995	0.324321520550992	0.0103546374915853	0.0310639124747558	0.776243028387552	0.776243028387552
Gpx4	ENSMUSG00000075706	0.853372965654504	0.853372965654504	0.0150443553124284	0.0451330659372853	0.643359829732651	0.853372965654504

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royalblue

Nicotine addiction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gabra1	ENSMUSG00000010803	0.10201855351568	0.306055660547039	0.704220158648919	0.704220158648919	0.432451767192269	0.648677650788403
Gria1	ENSMUSG00000020524	0.578113371816017	0.853907737111068	0.853907737111068	0.853907737111068	0.0847074989275801	0.25412249678274
Grin2b	ENSMUSG00000030209	0.822979901660618	0.822979901660618	0.822979901660618	0.822979901660618	0.822979901660618	0.822979901660618

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Striated Muscle Contraction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Actn3	ENSMUSG00000006457	0.252920381501207	0.577544706586058	0.577544706586058	0.577544706586058	0.45596561163947	0.577544706586058
Tnnc2	ENSMUSG00000017300	0.255530331334266	0.255530331334266	0.252545530864481	0.255530331334266	0.0325051220296005	0.0975153660888015
Tnni2	ENSMUSG00000031097	0.17924968721805	0.268874530827074	0.398829756175299	0.398829756175299	0.144820068500793	0.268874530827074
Mybpc2	ENSMUSG00000038670	0.503822527122732	0.640861491578951	0.640861491578951	0.640861491578951	0.327972855903273	0.640861491578951
Myl1	ENSMUSG00000061816	0.093641927103991	0.140462890655986	0.782117202022501	0.782117202022501	0.0575107614292585	0.140462890655986

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Muscle contraction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Actn3	ENSMUSG00000006457	0.252920381501207	0.577544706586058	0.577544706586058	0.577544706586058	0.45596561163947	0.577544706586058
Tnnc2	ENSMUSG00000017300	0.255530331334266	0.255530331334266	0.252545530864481	0.255530331334266	0.0325051220296005	0.0975153660888015
Tnni2	ENSMUSG00000031097	0.17924968721805	0.268874530827074	0.398829756175299	0.398829756175299	0.144820068500793	0.268874530827074
Mybpc2	ENSMUSG00000038670	0.503822527122732	0.640861491578951	0.640861491578951	0.640861491578951	0.327972855903273	0.640861491578951
Myl1	ENSMUSG00000061816	0.093641927103991	0.140462890655986	0.782117202022501	0.782117202022501	0.0575107614292585	0.140462890655986
Kcne1l	ENSMUSG00000090122	0.700168597929884	0.700168597929884	0.566285712787375	0.700168597929884	0.124210209545128	0.372630628635384

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sienna1

[1] “No significantly overrepresented pathways reported”

sienna3

[1] “No significantly overrepresented pathways reported”

slateblue2

[1] “No significantly overrepresented pathways reported”

thistle2

Neuroactive ligand-receptor interaction

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Gabrg1	ENSMUSG00000001260	0.759823034685568	0.759823034685568	0.694741105453749	0.759823034685568	0.590976010790092	0.759823034685568
Grm3	ENSMUSG00000003974	0.318952624781367	0.318952624781367	0.0620950549395545	0.186285164818664	0.318952624781367	0.318952624781367
Pomc	ENSMUSG00000020660	0.388869977560173	0.511420431658568	0.505504092080957	0.511420431658568	0.511420431658568	0.511420431658568
P2ry2	ENSMUSG00000032860	0.496922356453102	0.496922356453102	0.0579478375430677	0.173843512629203	0.451840588205062	0.496922356453102
Rxfp1	ENSMUSG00000034009	0.280002632651122	0.650262661949838	0.650262661949838	0.650262661949838	0.650262661949838	0.650262661949838
Htr2a	ENSMUSG00000034997	0.199128064946637	0.298692097419956	0.176451829330851	0.298692097419956	0.37032580521798	0.37032580521798
Grid1	ENSMUSG00000041078	1	1	0.425393263482293	1	1	1
Grm5	ENSMUSG00000049583	0.922060259310211	0.922060259310211	0.422982510357224	0.922060259310211	0.922060259310211	0.922060259310211

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white

Starch and sucrose metabolism

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Carbohydrate digestion and absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Salivary secretion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Pancreatic secretion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Metabolic pathways

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Alox8	ENSMUSG00000020891	0.920870614561017	0.920870614561017	0.77205234322561	0.920870614561017	0.566285712787375	0.920870614561017
Dpys	ENSMUSG00000022304	0.627814466256298	0.627814466256298	0.531764187487923	0.627814466256298	0.532150934397798	0.627814466256298
Hgd	ENSMUSG00000022821	0.926333123228344	0.926333123228344	0.853694531487825	0.926333123228344	0.454600801949285	0.926333123228344
Alas2	ENSMUSG00000025270	0.554415477279416	0.554415477279416	0.0723789610264069	0.217136883079221	0.554415477279416	0.554415477279416
Cyp24a1	ENSMUSG00000038567	0.68849422629413	0.770785031118676	0.770785031118676	0.770785031118676	0.770785031118676	0.770785031118676
Cyp2j5	ENSMUSG00000052520	0.705752031336119	0.705752031336119	0.507830090867449	0.705752031336119	0.240671523582595	0.705752031336119
Nt5c1a	ENSMUSG00000054958	0.707473958606095	0.707473958606095	0.0183083377354241	0.0549250132062725	0.265842347048319	0.398763520572479
Amd2	ENSMUSG00000063953	0.502464977245519	0.753697465868278	0.762507504068942	0.762507504068942	0.0183083377354242	0.0549250132062725
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Cyp4a12b	ENSMUSG00000078597	0.275387266314552	0.275387266314552	0.275387266314552	0.275387266314552	0.275387266314552	0.275387266314552
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Digestion of dietary carbohydrate

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Digestion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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Digestion and absorption

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Amy2a5	ENSMUSG00000074268	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a3	ENSMUSG00000093931	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a2	ENSMUSG00000096569	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867
Amy2a4	ENSMUSG00000096770	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867	0.0468363171026867

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yellow4

Fanconi anemia pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471
Fancd2	ENSMUSG00000034023	0.780851835278817	0.780851835278817	0.144820068500793	0.21723010275119	0.041737700208629	0.125213100625887

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Cell cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Tfdp1	ENSMUSG00000038482	0.511742979522636	0.641867098978198	0.288654423610209	0.641867098978198	0.641867098978198	0.641867098978198
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225

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Homologous recombination

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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mTOR signaling pathway

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Igf1	ENSMUSG00000020053	0.926658283600152	0.926658283600152	0.399548817627028	0.926658283600152	0.642366752097095	0.926658283600152
Rps6ka6	ENSMUSG00000025665	0.641616487517698	0.641616487517698	0.0741204440774082	0.222361332232225	0.296717426617604	0.445076139926407
Lamtor1	ENSMUSG00000030842	0.576973746230334	0.926441990075769	0.711650020253571	0.926441990075769	0.926441990075769	0.926441990075769
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Cell Cycle

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Fbxo5	ENSMUSG00000019773	0.576973746230334	0.643359829732651	0.576973746230334	0.643359829732651	0.643359829732651	0.643359829732651
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Cep41	ENSMUSG00000029790	0.643853282854191	0.926658283600152	0.578113371816017	0.926658283600152	0.926658283600152	0.926658283600152
Ruvbl1	ENSMUSG00000030079	0.926550375688041	0.926550375688041	0.513026869856283	0.769540304784424	0.299349060054895	0.769540304784424
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Tfdp1	ENSMUSG00000038482	0.511742979522636	0.641867098978198	0.288654423610209	0.641867098978198	0.641867098978198	0.641867098978198
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Cell Cycle, Mitotic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Fbxo5	ENSMUSG00000019773	0.576973746230334	0.643359829732651	0.576973746230334	0.643359829732651	0.643359829732651	0.643359829732651
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Cep41	ENSMUSG00000029790	0.643853282854191	0.926658283600152	0.578113371816017	0.926658283600152	0.926658283600152	0.926658283600152
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Tfdp1	ENSMUSG00000038482	0.511742979522636	0.641867098978198	0.288654423610209	0.641867098978198	0.641867098978198	0.641867098978198
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Kinesins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894

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M Phase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Fbxo5	ENSMUSG00000019773	0.576973746230334	0.643359829732651	0.576973746230334	0.643359829732651	0.643359829732651	0.643359829732651
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Cep41	ENSMUSG00000029790	0.643853282854191	0.926658283600152	0.578113371816017	0.926658283600152	0.926658283600152	0.926658283600152
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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MHC class II antigen presentation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sec24b	ENSMUSG00000001052	1	1	0.0113089139751576	0.0339267419254727	0.455625354715449	0.683438032073173
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894

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Resolution of D-loop Structures through Holliday Junction Intermediates

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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Factors involved in megakaryocyte development and platelet production

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894

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Cell Cycle Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Activation of the pre-replicative complex

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1

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Resolution of D-Loop Structures

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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Presynaptic phase of homologous DNA pairing and strand exchange

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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Activation of ATR in response to replication stress

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1

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Homologous DNA Pairing and Strand Exchange

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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COPI-dependent Golgi-to-ER retrograde traffic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894

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CS/DS degradation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Dcn	ENSMUSG00000019929	0.573205482926791	0.78180291566155	0.78180291566155	0.78180291566155	0.511742979522636	0.78180291566155
Hexb	ENSMUSG00000021665	0.513665062682276	0.5155648232968	0.11810342389482	0.354310271684459	0.5155648232968	0.5155648232968

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Intra-Golgi and retrograde Golgi-to-ER traffic

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894
Rabepk	ENSMUSG00000070953	0.926658283600152	0.926658283600152	0.0328221470541517	0.098466441162455	0.643359829732651	0.926658283600152

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EML4 and NUDC in mitotic spindle formation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Mitotic Prometaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Cep41	ENSMUSG00000029790	0.643853282854191	0.926658283600152	0.578113371816017	0.926658283600152	0.926658283600152	0.926658283600152
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Mitotic Telophase/Cytokinesis

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765

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Resolution of Sister Chromatid Cohesion

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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DNA Repair

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Ruvbl1	ENSMUSG00000030079	0.926550375688041	0.926550375688041	0.513026869856283	0.769540304784424	0.299349060054895	0.769540304784424
Rad18	ENSMUSG00000030254	0.575824878403157	0.575824878403157	0.058823267388015	0.0882349010820225	0.0113901882503033	0.0341705647509098
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471
Fancd2	ENSMUSG00000034023	0.780851835278817	0.780851835278817	0.144820068500793	0.21723010275119	0.041737700208629	0.125213100625887

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HDR through Homologous Recombination (HRR)

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Rad51c	ENSMUSG00000007646	0.643359829732651	0.853694531487825	0.853694531487825	0.853694531487825	0.643853282854191	0.853694531487825
Rad51	ENSMUSG00000027323	0.344663224299303	0.577829325134931	0.577829325134931	0.577829325134931	0.513665062682276	0.577829325134931
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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Golgi-to-ER retrograde transport

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894

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Mitotic G1 phase and G1/S transition

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Tfdp1	ENSMUSG00000038482	0.511742979522636	0.641867098978198	0.288654423610209	0.641867098978198	0.641867098978198	0.641867098978198

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RHO GTPases Activate Formins

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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Mitotic Metaphase and Anaphase

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Fbxo5	ENSMUSG00000019773	0.576973746230334	0.643359829732651	0.576973746230334	0.643359829732651	0.643359829732651	0.643359829732651
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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RHO GTPase Effectors

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Prc1	ENSMUSG00000038943	0.397384062266614	0.596076093399921	0.643359829732651	0.643359829732651	0.297095062262362	0.596076093399921
Bub1b	ENSMUSG00000040084	0.171859370212435	0.171859370212435	0.0158546704257247	0.047564011277174	0.058823267388015	0.0882349010820225
Cenpm	ENSMUSG00000068101	0.926658283600152	0.926658283600152	0.346527959006435	0.683438032073173	0.455625354715448	0.683438032073173
Seh1l	ENSMUSG00000079614	0.926658283600152	0.926658283600152	0.147458757705094	0.221188136557642	0.0592616003460512	0.177784801038154

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DNA Replication Pre-Initiation

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1

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Adaptive Immune System

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Sec24b	ENSMUSG00000001052	1	1	0.0113089139751576	0.0339267419254727	0.455625354715449	0.683438032073173
Kif20a	ENSMUSG00000003779	0.347639524025037	0.347639524025037	0.144820068500793	0.347639524025037	0.344663224299303	0.347639524025037
Kctd6	ENSMUSG00000021752	0.926550375688041	0.926550375688041	0.211844580334808	0.317766870502212	0.0553321944628787	0.165996583388636
Tuba1b	ENSMUSG00000023004	0.348008842235184	0.711854160331342	0.711854160331342	0.711854160331342	0.576973746230334	0.711854160331342
Kbtbd8	ENSMUSG00000030031	0.633577343537212	0.9255572759333	0.9255572759333	0.9255572759333	0.178901132102685	0.536703396308055
Kif23	ENSMUSG00000032254	0.777922216623952	0.7802108304765	0.0168921052924602	0.0506763158773805	0.7802108304765	0.7802108304765
Traip	ENSMUSG00000032586	0.298599969973533	0.863304304136274	0.575536202757516	0.863304304136274	0.926333123228344	0.926333123228344
Kif4	ENSMUSG00000034311	0.578396848531894	0.578396848531894	0.178901132102685	0.536703396308054	0.390750658104794	0.578396848531894
Klhl13	ENSMUSG00000036782	0.706831781264722	1	1	1	0.297095062262362	0.891285186787087

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G2/M Checkpoints

External Gene Name	Gene ID	Treatment	BH Treatment	Time	BH Time	Treatment by time	BH Treatment by time
Cdc45	ENSMUSG00000000028	0.780851835278818	0.92622377157404	0.25141795904251	0.754253877127531	0.92622377157404	0.92622377157404
Mcm5	ENSMUSG00000005410	0.024062085667391	0.0721862570021729	0.501782052576058	0.501782052576058	0.299349060054895	0.449023590082343
Orc1	ENSMUSG00000028587	0.117797451854564	0.353392355563692	0.567207316884045	0.850810975326067	1	1
Blm	ENSMUSG00000030528	0.392985378348026	0.392985378348026	0.00768144932639892	0.0230443479791968	0.0726276229843141	0.108941434476471

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Analysis performed by Ann Wells

The Carter Lab The Jackson Laboratory 2023

ann.wells@jax.org