Introduction

This dataset contains nine tissues (heart, hippocampus, hypothalamus, kidney, liver, prefrontal cortex, skeletal muscle, small intestine, and spleen) from C57BL/6J mice that were fed 2-deoxyglucose (6g/L) through their drinking water for 96hrs or 4wks. 96hr mice were given their 2DG treatment 2 weeks after the other cohort started the 4 week treatment. The organs from the mice were harvested and processed for metabolomics and transcriptomics. The data in this document pertains to the transcriptomics data only. The counts that were used were FPKM normalized before being log transformed. It was determined that sample A113 had low RNAseq quality and through further analyses with PCA, MA plots, and clustering was an outlier and will be removed for the rest of the analyses performed. This document will the significance of the main effects and their interaction for each gene in each module.

needed.packages <- c("tidyverse", "here", "functional", "gplots", "dplyr", "GeneOverlap", "R.utils", "reshape2","magrittr","data.table", "RColorBrewer","preprocessCore", "ARTool","emmeans", "phia", "gprofiler2","rlist", "plotly","kableExtra","foreach","doParallel","doFuture","downloadthis")
for(i in 1:length(needed.packages)){library(needed.packages[i], character.only = TRUE)}

source(here("source_files","WGCNA_source.R"))
WGCNA.pathway <-readRDS(here("Data","Prefrontal Cortex","Chang_B6_96hr_4wk_gprofiler_pathway_annotation_list_prefrontal_cortex_WGCNA.RData"))

WGCNA.gene <-readRDS(here("Data","Prefrontal Cortex","Chang_B6_96hr_4wk_gprofiler_gene_annotation_list_prefrontal_cortex_WGCNA.RData"))

tdata.FPKM.sample.info <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_phenotypes.RData"))

tdata.FPKM <- readRDS(here("Data","20190406_RNAseq_B6_4wk_2DG_counts_numeric.RData"))

log.tdata.FPKM <- log(tdata.FPKM + 1)
log.tdata.FPKM <- as.data.frame(log.tdata.FPKM)

log.tdata.FPKM.sample.info <- cbind(log.tdata.FPKM, tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()

log.tdata.FPKM.subset <- log.tdata.FPKM[,colMeans(log.tdata.FPKM != 0) > 0.5] 

log.tdata.FPKM.sample.info.subset <- cbind(log.tdata.FPKM.subset,tdata.FPKM.sample.info[,27238:27240])  

log.tdata.FPKM.sample.info <- log.tdata.FPKM.sample.info %>% rownames_to_column() %>% filter(rowname != "A113") %>% column_to_rownames()

log.tdata.FPKM.sample.info.subset.prefrontal.cortex <- log.tdata.FPKM.sample.info.subset %>% rownames_to_column() %>% filter(Tissue == "Pre-frontal Cortex") %>% column_to_rownames()

ensembl.location <- readRDS(here("Data","Ensembl_gene_id_and_location.RData"))

Matched<-readRDS(here("Data","Prefrontal Cortex","Annotated_genes_in_prefrontal_cortex_WGCNA_Chang_B6_96hr_4wk.RData"))


module.names <- Matched$X..Module.
name <- str_split(module.names,"_")
samples <-c()
for(i in 1:length(name)){
samples[[i]] <- name[[i]][2]
}  
name2 <- stringr::str_split(samples,"\"")
mod.names <- c()
for(i in 1:length(name2)){
   mod.names[[i]] <- name2[[i]][1]
}
name2 <- unlist(mod.names)
modules <- unique(mod.names)
modules <- unlist(modules)

ANOVA

log.tdata.FPKM.sample.info.subset.prefrontal.cortex$Time <- as.factor(log.tdata.FPKM.sample.info.subset.prefrontal.cortex$Time)
log.tdata.FPKM.sample.info.subset.prefrontal.cortex$Treatment <- as.factor(log.tdata.FPKM.sample.info.subset.prefrontal.cortex$Treatment)

ANOVA.gene.pathways(WGCNA.gene, log.tdata.FPKM.sample.info.subset.prefrontal.cortex)

antiquewhite

[1] “No significantly overrepresented pathways reported”

aquamarine

Lysine degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kmt2a ENSMUSG00000002028 0.0763619660358785 0.220200812784373 0.146800541856249 0.220200812784373 0.926550375688041 0.926550375688041
Kmt2b ENSMUSG00000006307 0.853372965654504 0.853372965654504 0.0221230395928304 0.0663691187784912 0.514934023620345 0.772401035430518
Nsd1 ENSMUSG00000021488 0.0579478375430678 0.0869217563146017 0.0566379395854602 0.0869217563146017 0.926550375688041 0.926550375688041
Kmt2e ENSMUSG00000029004 0.255530331334265 0.383295497001398 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513
Plod2 ENSMUSG00000032374 0.093084640707941 0.179904257106569 0.11993617140438 0.179904257106569 0.641867098978198 0.641867098978198
Kmt2c ENSMUSG00000038056 0.177153312234059 0.317766870502212 0.211844580334808 0.317766870502212 0.926658283600152 0.926658283600152
Setd1b ENSMUSG00000038384 0.0969812105731562 0.290943631719469 0.211110344399808 0.316665516599712 0.577829325134931 0.577829325134931
Setd2 ENSMUSG00000044791 0.294820734456232 0.450143880930327 0.300095920620218 0.450143880930327 0.926550375688041 0.926550375688041
Suv420h1 ENSMUSG00000045098 0.148772260628989 0.223158390943484 0.113498953177704 0.223158390943484 0.926003599371282 0.926003599371282
Kmt2d ENSMUSG00000048154 0.0919695072173337 0.181275797044394 0.120850531362929 0.181275797044394 0.578396848531894 0.578396848531894
Whsc1l1 ENSMUSG00000054823 0.0451153644990944 0.135346093497283 0.575824878403157 0.711240436189781 0.711240436189781 0.711240436189781
Acat3 ENSMUSG00000062480 0.00755778364492931 0.0226733509347879 0.577829325134931 0.866743987702397 0.926658283600152 0.926658283600152

mRNA surveillance pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Acin1 ENSMUSG00000022185 0.254414773803597 0.381622160705395 0.0583853430099097 0.175156029029729 0.5155648232968 0.5155648232968
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Pabpc5 ENSMUSG00000034732 0.00159435459956481 0.00478306379869444 0.779075411222437 0.779075411222437 0.255158975839805 0.382738463759707
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Ppp2r3a ENSMUSG00000043154 0.0548979200435554 0.0823468800653331 0.0331400397096515 0.0823468800653331 0.926550375688041 0.926550375688041
Cpsf6 ENSMUSG00000055531 0.0312459040565944 0.093737712169783 0.576973746230334 0.711034989117171 0.711034989117171 0.711034989117171
Dazap1 ENSMUSG00000069565 0.5155648232968 0.7733472349452 0.0315593554855452 0.0946780664566356 0.926550375688041 0.926550375688041
Msi2 ENSMUSG00000069769 0.295581119060361 0.443371678590541 0.180293335960318 0.443371678590541 0.643359829732651 0.643359829732651
Gspt2 ENSMUSG00000071723 0.148115998140416 0.444347994421247 0.782117202022501 0.782117202022501 0.711650020253571 0.782117202022501
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf9 ENSMUSG00000002325 0.0328221470541517 0.098466441162455 0.853372965654504 0.853372965654504 0.21549027811633 0.323235417174495
Ikbkg ENSMUSG00000004221 0.0073134885581712 0.0219404656745136 0.146141353215796 0.219212029823693 0.641867098978198 0.641867098978198
Tab2 ENSMUSG00000015755 0.711240436189781 0.924987846321933 0.11595859961889 0.347875798856669 0.924987846321933 0.924987846321933
A530054K11Rik ENSMUSG00000021510 0.00768144932639892 0.0230443479791968 0.105759219123976 0.158638828685963 0.297848640636702 0.297848640636702
Eif2ak2 ENSMUSG00000024079 0.0763619660358786 0.114542949053818 0.044737329683373 0.114542949053818 0.853801250889739 0.853801250889739
Zfp871 ENSMUSG00000024298 0.0104326641569827 0.0312979924709482 0.0741204440774082 0.111180666116112 1 1
Pou2f1 ENSMUSG00000026565 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.643359829732651 0.643359829732651
Il1b ENSMUSG00000027398 0.255530331334266 0.383295497001398 0.254414773803597 0.383295497001398 0.450444934184774 0.450444934184774
Zfp108 ENSMUSG00000030486 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026 0.255530331334266 0.766590994002797
Irak1 ENSMUSG00000031392 0.782117202022501 0.782117202022501 0.118714930081337 0.35614479024401 0.643359829732651 0.782117202022501
Zfp551 ENSMUSG00000034071 0.45596561163947 0.45596561163947 0.254414773803596 0.450143880930327 0.300095920620218 0.450143880930327
Zfp39 ENSMUSG00000037001 0.179249687218049 0.268874530827074 0.0958690133561599 0.268874530827074 0.638310022345193 0.638310022345193
Ddx58 ENSMUSG00000040296 0.0964252305385471 0.144637845807821 0.0331400397096515 0.0994201191289544 1 1
Tnfrsf14 ENSMUSG00000042333 0.120850531362929 0.148115998140416 0.117185073436597 0.148115998140416 0.148115998140416 0.148115998140416
Ikbke ENSMUSG00000042349 0.212942741031873 0.254041925545275 0.254041925545275 0.254041925545275 0.109793509122179 0.254041925545275
Zfp623 ENSMUSG00000050846 0.456305241393103 0.456305241393103 0.345037391052887 0.456305241393103 0.216214347033995 0.456305241393103
Zfp961 ENSMUSG00000052446 0.18064054691103 0.447899954960299 0.298599969973533 0.447899954960299 0.578396848531894 0.578396848531894
Zfp78 ENSMUSG00000055150 0.17924968721805 0.537749061654149 0.926333123228344 0.926333123228344 0.455625354715449 0.683438032073173
Bak1 ENSMUSG00000057789 0.638824656785692 0.78148726569172 0.0592616003460512 0.177784801038154 0.78148726569172 0.78148726569172
Zfp809 ENSMUSG00000057982 0.347639524025037 0.712057867818062 0.712057867818062 0.712057867818062 0.641867098978198 0.712057867818062
Rsl1 ENSMUSG00000058900 0.0315593554855452 0.0946780664566356 0.5155648232968 0.5155648232968 0.455625354715449 0.5155648232968
Zfp74 ENSMUSG00000059975 0.12935516793705 0.213248926739148 0.142165951159432 0.213248926739148 0.438516479093275 0.438516479093275
B2m ENSMUSG00000060802 0.0241933715424143 0.0725801146272428 0.120545895661628 0.180818843492441 0.853480389728993 0.853480389728993
Zfp27 ENSMUSG00000062040 0.0447373296833729 0.0671059945250594 0.0445485589872461 0.0671059945250594 0.778747761033626 0.778747761033626
Zfp442 ENSMUSG00000068130 0.256271555563966 0.509798138101151 0.509798138101151 0.509798138101151 0.454600801949285 0.509798138101151
Zfp946 ENSMUSG00000071266 0.0447373296833729 0.134211989050119 0.638310022345193 0.638310022345193 0.452880492349546 0.638310022345193
H2-Q6 ENSMUSG00000073409 0.7802108304765 0.78180291566155 0.78180291566155 0.78180291566155 0.643359829732651 0.78180291566155
Zfp558 ENSMUSG00000074500 0.174692232033629 0.443371678590541 0.295581119060361 0.443371678590541 0.926550375688041 0.926550375688041
5830428H23Rik ENSMUSG00000074733 0.578396848531894 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Gm13157 ENSMUSG00000078495 0.710416009055326 0.710416009055326 0.0579478375430677 0.173843512629203 0.300095920620218 0.450143880930327
Gm14434 ENSMUSG00000078881 0.710416009055326 0.710416009055326 0.300095920620218 0.710416009055326 0.640355507848752 0.710416009055326

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sp1 ENSMUSG00000001280 0.211110344399808 0.316665516599712 0.144820068500793 0.316665516599712 0.338592117141989 0.338592117141989
Kmt2a ENSMUSG00000002028 0.0763619660358785 0.220200812784373 0.146800541856249 0.220200812784373 0.926550375688041 0.926550375688041
Tfam ENSMUSG00000003923 0.0240620856673909 0.0721862570021727 0.926658283600152 0.926658283600152 0.300095920620218 0.450143880930327
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Ctcf ENSMUSG00000005698 0.345037391052887 0.51755608657933 0.0964252305385472 0.289275691615642 1 1
Nr2c1 ENSMUSG00000005897 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191 0.642864324224729 0.643853282854191
Kmt2b ENSMUSG00000006307 0.853372965654504 0.853372965654504 0.0221230395928304 0.0663691187784912 0.514934023620345 0.772401035430518
Arid1a ENSMUSG00000007880 0.511097249598474 0.514934023620345 0.0753654386865988 0.226096316059796 0.514934023620345 0.514934023620345
Smurf2 ENSMUSG00000018363 0.253294730253594 0.759884190760783 0.853801250889739 0.853801250889739 0.711240436189781 0.853801250889739
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Psmc5 ENSMUSG00000020708 0.399548817627028 0.399548817627028 0.29252580908486 0.399548817627028 0.399548817627028 0.399548817627028
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Mta1 ENSMUSG00000021144 0.255901190956604 0.383851786434906 0.058823267388015 0.176469802164045 0.578113371816017 0.578113371816017
A530054K11Rik ENSMUSG00000021510 0.00768144932639892 0.0230443479791968 0.105759219123976 0.158638828685963 0.297848640636702 0.297848640636702
Plk2 ENSMUSG00000021701 0.78180291566155 0.78180291566155 0.513665062682276 0.770497594023414 0.398108175780842 0.770497594023414
Nup155 ENSMUSG00000022142 0.00683713071940991 0.0205113921582297 0.392243127063687 0.588364690595531 0.643359829732651 0.643359829732651
Fyttd1 ENSMUSG00000022800 0.0741204440774081 0.222361332232224 0.711650020253571 0.711650020253571 0.398108175780842 0.597162263671263
Eaf2 ENSMUSG00000022838 0.711650020253571 0.926550375688041 0.299349060054895 0.898047180164686 0.926550375688041 0.926550375688041
Zfp871 ENSMUSG00000024298 0.0104326641569827 0.0312979924709482 0.0741204440774082 0.111180666116112 1 1
Iws1 ENSMUSG00000024384 0.455965611639469 0.683948417459204 0.144820068500793 0.43446020550238 0.78148726569172 0.78148726569172
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Banp ENSMUSG00000025316 0.400265374208515 0.600398061312773 0.0969812105731562 0.290943631719469 0.782117202022501 0.782117202022501
Tfap2b ENSMUSG00000025927 0.45149265530335 0.45149265530335 0.023931046492469 0.071793139477407 0.298974794311434 0.448462191467151
Pou2f1 ENSMUSG00000026565 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.643359829732651 0.643359829732651
Esrrg ENSMUSG00000026610 0.0766111619812296 0.229833485943689 0.21549027811633 0.323235417174495 0.853480389728993 0.853480389728993
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Nup35 ENSMUSG00000026999 0.0566379395854603 0.169913818756381 0.400265374208515 0.400265374208515 0.398108175780842 0.400265374208515
Polr3gl ENSMUSG00000028104 1 1 0.0113089139751576 0.0339267419254727 0.926550375688041 1
Ccne2 ENSMUSG00000028212 0.171859370212435 0.399548817627028 0.399548817627028 0.399548817627028 0.299349060054895 0.399548817627028
Kmt2e ENSMUSG00000029004 0.255530331334265 0.383295497001398 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513
Nelfa ENSMUSG00000029111 0.455625354715449 0.710416009055326 0.710416009055326 0.710416009055326 0.578113371816017 0.710416009055326
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Zkscan1 ENSMUSG00000029729 0.000747579742686132 0.00224273922805839 0.455625354715449 0.643853282854191 0.643853282854191 0.643853282854191
Zfp108 ENSMUSG00000030486 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026 0.255530331334266 0.766590994002797
Blm ENSMUSG00000030528 0.180293335960318 0.270440003940477 0.096425230538547 0.270440003940477 0.711650020253571 0.711650020253571
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Wrn ENSMUSG00000031583 0.214037080764326 0.445642593393544 0.297095062262363 0.445642593393544 0.513026869856283 0.513026869856283
Brd7 ENSMUSG00000031660 0.511742979522635 0.643359829732651 0.174692232033629 0.524076696100888 0.643359829732651 0.643359829732651
Psmb10 ENSMUSG00000031897 0.511742979522636 0.771451162979439 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501
Maml2 ENSMUSG00000031925 0.343160411648939 0.514740617473408 0.0323469380768478 0.0970408142305435 0.853587578053106 0.853587578053106
Taf1d ENSMUSG00000031939 0.216214347033994 0.597162263671263 0.398108175780842 0.597162263671263 0.853801250889739 0.853801250889739
Pin1 ENSMUSG00000032171 0.779238691542963 0.779238691542963 0.0761127945805736 0.228338383741721 0.454600801949285 0.681901202923927
Rnf111 ENSMUSG00000032217 0.0238002551499929 0.0714007654499788 0.254414773803597 0.381622160705395 0.711854160331342 0.711854160331342
Tcf12 ENSMUSG00000032228 0.853801250889739 0.853801250889739 0.0592616003460512 0.177784801038154 0.852940894477647 0.853801250889739
Zfp551 ENSMUSG00000034071 0.45596561163947 0.45596561163947 0.254414773803596 0.450143880930327 0.300095920620218 0.450143880930327
Med13 ENSMUSG00000034297 0.0306217702495172 0.0654108384650599 0.0436072256433733 0.0654108384650599 0.399548817627028 0.399548817627028
Cnot6l ENSMUSG00000034724 0.0969812105731562 0.290943631719469 0.642366752097095 0.642366752097095 0.640861491578951 0.642366752097095
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Ints6 ENSMUSG00000035161 0.010906560635693 0.032719681907079 0.214037080764326 0.214037080764326 0.174692232033629 0.214037080764326
Cnot3 ENSMUSG00000035632 0.578113371816017 0.853694531487825 0.256271555563966 0.768814666691898 0.853694531487825 0.853694531487825
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Rmi2 ENSMUSG00000037991 0.85326530496423 0.85326530496423 0.00683713071940993 0.0205113921582298 0.576687400573867 0.85326530496423
Setd1b ENSMUSG00000038384 0.0969812105731562 0.290943631719469 0.211110344399808 0.316665516599712 0.577829325134931 0.577829325134931
Taf4a ENSMUSG00000039117 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.643853282854191 0.643853282854191
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Cdk6 ENSMUSG00000040274 0.711034989117171 0.711034989117171 0.0577292451600847 0.173187735480254 0.643112334413352 0.711034989117171
Cdk13 ENSMUSG00000041297 0.00463747559282086 0.0139124267784626 0.343537039781257 0.515305559671886 0.781170242226513 0.781170242226513
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Pbrm1 ENSMUSG00000042323 0.347639524025037 0.782117202022501 0.782117202022501 0.782117202022501 0.78180291566155 0.782117202022501
Nr1h4 ENSMUSG00000047638 0.148115998140416 0.222173997210623 0.294820734456232 0.294820734456232 0.091411676944639 0.222173997210623
Tnrc6b ENSMUSG00000047888 0.0232795908282423 0.0698387724847269 0.11595859961889 0.173937899428335 0.78180291566155 0.78180291566155
Kmt2d ENSMUSG00000048154 0.0919695072173337 0.181275797044394 0.120850531362929 0.181275797044394 0.578396848531894 0.578396848531894
Aff4 ENSMUSG00000049470 0.0334587898203823 0.100376369461147 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152
Maml1 ENSMUSG00000050567 0.395928178642446 0.395928178642446 0.346527959006435 0.395928178642446 0.346899083932133 0.395928178642446
Prkaa1 ENSMUSG00000050697 0.0753654386865988 0.226096316059796 0.711650020253571 0.926658283600152 0.926658283600152 0.926658283600152
Taf7 ENSMUSG00000051316 0.0168921052924602 0.0506763158773805 0.455625354715449 0.455625354715449 0.454942951775342 0.455625354715449
Zfp961 ENSMUSG00000052446 0.18064054691103 0.447899954960299 0.298599969973533 0.447899954960299 0.578396848531894 0.578396848531894
Tnrc6a ENSMUSG00000052707 0.178901132102685 0.536703396308054 1 1 0.852832278580641 1
Ercc6 ENSMUSG00000054051 0.0441715176243982 0.0763619660358786 0.0763619660358786 0.0763619660358786 0.0761127945805735 0.0763619660358786
Mdm4 ENSMUSG00000054387 0.00463747559282086 0.0139124267784626 0.116265430850263 0.174398146275395 0.926333123228344 0.926333123228344
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Zfp78 ENSMUSG00000055150 0.17924968721805 0.537749061654149 0.926333123228344 0.926333123228344 0.455625354715449 0.683438032073173
Tsnax ENSMUSG00000056820 0.300095920620218 0.300095920620218 0.0763619660358787 0.229085898107636 0.255901190956604 0.300095920620218
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Rsl1 ENSMUSG00000058900 0.0315593554855452 0.0946780664566356 0.5155648232968 0.5155648232968 0.455625354715449 0.5155648232968
Zfp74 ENSMUSG00000059975 0.12935516793705 0.213248926739148 0.142165951159432 0.213248926739148 0.438516479093275 0.438516479093275
Zfp27 ENSMUSG00000062040 0.0447373296833729 0.0671059945250594 0.0445485589872461 0.0671059945250594 0.778747761033626 0.778747761033626
Brpf3 ENSMUSG00000063952 0.511097249598474 0.766645874397711 0.0321889748775514 0.0965669246326542 0.85117361048289 0.85117361048289
Zfp442 ENSMUSG00000068130 0.256271555563966 0.509798138101151 0.509798138101151 0.509798138101151 0.454600801949285 0.509798138101151
Taf1a ENSMUSG00000072258 0.146800541856249 0.440401625568746 0.578396848531894 0.853372965654504 0.853372965654504 0.853372965654504
Zfp558 ENSMUSG00000074500 0.174692232033629 0.443371678590541 0.295581119060361 0.443371678590541 0.926550375688041 0.926550375688041
5830428H23Rik ENSMUSG00000074733 0.578396848531894 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951
Med12 ENSMUSG00000079487 0.514934023620345 0.5155648232968 0.0753654386865988 0.226096316059796 0.5155648232968 0.5155648232968
Zfp882 ENSMUSG00000089857 0.0168921052924602 0.0506763158773805 0.148115998140416 0.222173997210623 0.347639524025037 0.347639524025037
Hist2h4 ENSMUSG00000091405 0.642366752097095 0.853694531487825 0.450794830295118 0.853694531487825 0.853694531487825 0.853694531487825

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sp1 ENSMUSG00000001280 0.211110344399808 0.316665516599712 0.144820068500793 0.316665516599712 0.338592117141989 0.338592117141989
Kmt2a ENSMUSG00000002028 0.0763619660358785 0.220200812784373 0.146800541856249 0.220200812784373 0.926550375688041 0.926550375688041
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Ctcf ENSMUSG00000005698 0.345037391052887 0.51755608657933 0.0964252305385472 0.289275691615642 1 1
Nr2c1 ENSMUSG00000005897 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191 0.642864324224729 0.643853282854191
Kmt2b ENSMUSG00000006307 0.853372965654504 0.853372965654504 0.0221230395928304 0.0663691187784912 0.514934023620345 0.772401035430518
Arid1a ENSMUSG00000007880 0.511097249598474 0.514934023620345 0.0753654386865988 0.226096316059796 0.514934023620345 0.514934023620345
Smurf2 ENSMUSG00000018363 0.253294730253594 0.759884190760783 0.853801250889739 0.853801250889739 0.711240436189781 0.853801250889739
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Psmc5 ENSMUSG00000020708 0.399548817627028 0.399548817627028 0.29252580908486 0.399548817627028 0.399548817627028 0.399548817627028
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
A530054K11Rik ENSMUSG00000021510 0.00768144932639892 0.0230443479791968 0.105759219123976 0.158638828685963 0.297848640636702 0.297848640636702
Plk2 ENSMUSG00000021701 0.78180291566155 0.78180291566155 0.513665062682276 0.770497594023414 0.398108175780842 0.770497594023414
Fyttd1 ENSMUSG00000022800 0.0741204440774081 0.222361332232224 0.711650020253571 0.711650020253571 0.398108175780842 0.597162263671263
Eaf2 ENSMUSG00000022838 0.711650020253571 0.926550375688041 0.299349060054895 0.898047180164686 0.926550375688041 0.926550375688041
Zfp871 ENSMUSG00000024298 0.0104326641569827 0.0312979924709482 0.0741204440774082 0.111180666116112 1 1
Iws1 ENSMUSG00000024384 0.455965611639469 0.683948417459204 0.144820068500793 0.43446020550238 0.78148726569172 0.78148726569172
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Banp ENSMUSG00000025316 0.400265374208515 0.600398061312773 0.0969812105731562 0.290943631719469 0.782117202022501 0.782117202022501
Tfap2b ENSMUSG00000025927 0.45149265530335 0.45149265530335 0.023931046492469 0.071793139477407 0.298974794311434 0.448462191467151
Pou2f1 ENSMUSG00000026565 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.643359829732651 0.643359829732651
Esrrg ENSMUSG00000026610 0.0766111619812296 0.229833485943689 0.21549027811633 0.323235417174495 0.853480389728993 0.853480389728993
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Ccne2 ENSMUSG00000028212 0.171859370212435 0.399548817627028 0.399548817627028 0.399548817627028 0.299349060054895 0.399548817627028
Kmt2e ENSMUSG00000029004 0.255530331334265 0.383295497001398 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513
Nelfa ENSMUSG00000029111 0.455625354715449 0.710416009055326 0.710416009055326 0.710416009055326 0.578113371816017 0.710416009055326
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Zkscan1 ENSMUSG00000029729 0.000747579742686132 0.00224273922805839 0.455625354715449 0.643853282854191 0.643853282854191 0.643853282854191
Zfp108 ENSMUSG00000030486 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026 0.255530331334266 0.766590994002797
Blm ENSMUSG00000030528 0.180293335960318 0.270440003940477 0.096425230538547 0.270440003940477 0.711650020253571 0.711650020253571
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Wrn ENSMUSG00000031583 0.214037080764326 0.445642593393544 0.297095062262363 0.445642593393544 0.513026869856283 0.513026869856283
Brd7 ENSMUSG00000031660 0.511742979522635 0.643359829732651 0.174692232033629 0.524076696100888 0.643359829732651 0.643359829732651
Psmb10 ENSMUSG00000031897 0.511742979522636 0.771451162979439 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501
Maml2 ENSMUSG00000031925 0.343160411648939 0.514740617473408 0.0323469380768478 0.0970408142305435 0.853587578053106 0.853587578053106
Pin1 ENSMUSG00000032171 0.779238691542963 0.779238691542963 0.0761127945805736 0.228338383741721 0.454600801949285 0.681901202923927
Rnf111 ENSMUSG00000032217 0.0238002551499929 0.0714007654499788 0.254414773803597 0.381622160705395 0.711854160331342 0.711854160331342
Tcf12 ENSMUSG00000032228 0.853801250889739 0.853801250889739 0.0592616003460512 0.177784801038154 0.852940894477647 0.853801250889739
Zfp551 ENSMUSG00000034071 0.45596561163947 0.45596561163947 0.254414773803596 0.450143880930327 0.300095920620218 0.450143880930327
Med13 ENSMUSG00000034297 0.0306217702495172 0.0654108384650599 0.0436072256433733 0.0654108384650599 0.399548817627028 0.399548817627028
Cnot6l ENSMUSG00000034724 0.0969812105731562 0.290943631719469 0.642366752097095 0.642366752097095 0.640861491578951 0.642366752097095
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Ints6 ENSMUSG00000035161 0.010906560635693 0.032719681907079 0.214037080764326 0.214037080764326 0.174692232033629 0.214037080764326
Cnot3 ENSMUSG00000035632 0.578113371816017 0.853694531487825 0.256271555563966 0.768814666691898 0.853694531487825 0.853694531487825
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Rmi2 ENSMUSG00000037991 0.85326530496423 0.85326530496423 0.00683713071940993 0.0205113921582298 0.576687400573867 0.85326530496423
Setd1b ENSMUSG00000038384 0.0969812105731562 0.290943631719469 0.211110344399808 0.316665516599712 0.577829325134931 0.577829325134931
Taf4a ENSMUSG00000039117 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.643853282854191 0.643853282854191
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Cdk6 ENSMUSG00000040274 0.711034989117171 0.711034989117171 0.0577292451600847 0.173187735480254 0.643112334413352 0.711034989117171
Cdk13 ENSMUSG00000041297 0.00463747559282086 0.0139124267784626 0.343537039781257 0.515305559671886 0.781170242226513 0.781170242226513
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Pbrm1 ENSMUSG00000042323 0.347639524025037 0.782117202022501 0.782117202022501 0.782117202022501 0.78180291566155 0.782117202022501
Nr1h4 ENSMUSG00000047638 0.148115998140416 0.222173997210623 0.294820734456232 0.294820734456232 0.091411676944639 0.222173997210623
Kmt2d ENSMUSG00000048154 0.0919695072173337 0.181275797044394 0.120850531362929 0.181275797044394 0.578396848531894 0.578396848531894
Aff4 ENSMUSG00000049470 0.0334587898203823 0.100376369461147 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152
Maml1 ENSMUSG00000050567 0.395928178642446 0.395928178642446 0.346527959006435 0.395928178642446 0.346899083932133 0.395928178642446
Prkaa1 ENSMUSG00000050697 0.0753654386865988 0.226096316059796 0.711650020253571 0.926658283600152 0.926658283600152 0.926658283600152
Taf7 ENSMUSG00000051316 0.0168921052924602 0.0506763158773805 0.455625354715449 0.455625354715449 0.454942951775342 0.455625354715449
Zfp961 ENSMUSG00000052446 0.18064054691103 0.447899954960299 0.298599969973533 0.447899954960299 0.578396848531894 0.578396848531894
Mdm4 ENSMUSG00000054387 0.00463747559282086 0.0139124267784626 0.116265430850263 0.174398146275395 0.926333123228344 0.926333123228344
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Zfp78 ENSMUSG00000055150 0.17924968721805 0.537749061654149 0.926333123228344 0.926333123228344 0.455625354715449 0.683438032073173
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Rsl1 ENSMUSG00000058900 0.0315593554855452 0.0946780664566356 0.5155648232968 0.5155648232968 0.455625354715449 0.5155648232968
Zfp74 ENSMUSG00000059975 0.12935516793705 0.213248926739148 0.142165951159432 0.213248926739148 0.438516479093275 0.438516479093275
Zfp27 ENSMUSG00000062040 0.0447373296833729 0.0671059945250594 0.0445485589872461 0.0671059945250594 0.778747761033626 0.778747761033626
Brpf3 ENSMUSG00000063952 0.511097249598474 0.766645874397711 0.0321889748775514 0.0965669246326542 0.85117361048289 0.85117361048289
Zfp442 ENSMUSG00000068130 0.256271555563966 0.509798138101151 0.509798138101151 0.509798138101151 0.454600801949285 0.509798138101151
Zfp558 ENSMUSG00000074500 0.174692232033629 0.443371678590541 0.295581119060361 0.443371678590541 0.926550375688041 0.926550375688041
5830428H23Rik ENSMUSG00000074733 0.578396848531894 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951
Med12 ENSMUSG00000079487 0.514934023620345 0.5155648232968 0.0753654386865988 0.226096316059796 0.5155648232968 0.5155648232968
Zfp882 ENSMUSG00000089857 0.0168921052924602 0.0506763158773805 0.148115998140416 0.222173997210623 0.347639524025037 0.347639524025037
Hist2h4 ENSMUSG00000091405 0.642366752097095 0.853694531487825 0.450794830295118 0.853694531487825 0.853694531487825 0.853694531487825

mRNA Splicing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.342026805366747 0.589478067522039 0.392985378348026 0.589478067522039 0.642864324224729 0.642864324224729
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Ddx42 ENSMUSG00000020705 0.0761127945805735 0.228338383741721 0.211844580334808 0.317766870502212 0.513026869856283 0.513026869856283
Eftud2 ENSMUSG00000020929 0.0953125666339397 0.285937699901819 0.852940894477647 0.852940894477647 0.779888212132595 0.852940894477647
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Ddx46 ENSMUSG00000021500 0.00412583181225651 0.0123774954367695 0.041737700208629 0.0626065503129434 0.252545530864481 0.252545530864481
Cwc27 ENSMUSG00000021715 0.0592616003460512 0.0888924005190768 0.000819575681707138 0.00245872704512142 0.297095062262363 0.297095062262363
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Sf1 ENSMUSG00000024949 0.578113371816017 0.643359829732651 0.0756145297453648 0.226843589236094 0.643359829732651 0.643359829732651
Cwc22 ENSMUSG00000027014 0.214764523938594 0.322146785907891 0.0763619660358787 0.229085898107636 0.454942951775341 0.454942951775341
Ybx1 ENSMUSG00000028639 0.852940894477647 0.852940894477647 0.0953125666339397 0.285937699901819 0.5155648232968 0.7733472349452
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Gpkow ENSMUSG00000031148 0.0761127945805736 0.228338383741721 0.453225835454266 0.45596561163947 0.45596561163947 0.45596561163947
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Rbmxl1 ENSMUSG00000037070 0.0241933715424143 0.0725801146272428 0.120545895661627 0.180818843492441 0.576973746230334 0.576973746230334
Srrm2 ENSMUSG00000039218 0.254414773803597 0.381622160705395 0.00768144932639892 0.0230443479791968 0.514934023620345 0.514934023620345
Hnrnpu ENSMUSG00000039630 0.299349060054895 0.449023590082343 0.0723789610264069 0.217136883079221 0.711650020253571 0.711650020253571
Elavl1 ENSMUSG00000040028 0.00289311433957183 0.00867934301871548 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Hnrnph2 ENSMUSG00000045427 0.0325051220296005 0.0501881847305735 0.0334587898203823 0.0501881847305735 0.853801250889739 0.853801250889739
Prpf40a ENSMUSG00000061136 0.0075577836449293 0.0226733509347879 0.142165951159432 0.213248926739148 0.710208797518812 0.710208797518812
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951

mRNA Splicing - Major Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.342026805366747 0.589478067522039 0.392985378348026 0.589478067522039 0.642864324224729 0.642864324224729
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Ddx42 ENSMUSG00000020705 0.0761127945805735 0.228338383741721 0.211844580334808 0.317766870502212 0.513026869856283 0.513026869856283
Eftud2 ENSMUSG00000020929 0.0953125666339397 0.285937699901819 0.852940894477647 0.852940894477647 0.779888212132595 0.852940894477647
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Ddx46 ENSMUSG00000021500 0.00412583181225651 0.0123774954367695 0.041737700208629 0.0626065503129434 0.252545530864481 0.252545530864481
Cwc27 ENSMUSG00000021715 0.0592616003460512 0.0888924005190768 0.000819575681707138 0.00245872704512142 0.297095062262363 0.297095062262363
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Sf1 ENSMUSG00000024949 0.578113371816017 0.643359829732651 0.0756145297453648 0.226843589236094 0.643359829732651 0.643359829732651
Cwc22 ENSMUSG00000027014 0.214764523938594 0.322146785907891 0.0763619660358787 0.229085898107636 0.454942951775341 0.454942951775341
Ybx1 ENSMUSG00000028639 0.852940894477647 0.852940894477647 0.0953125666339397 0.285937699901819 0.5155648232968 0.7733472349452
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Gpkow ENSMUSG00000031148 0.0761127945805736 0.228338383741721 0.453225835454266 0.45596561163947 0.45596561163947 0.45596561163947
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Rbmxl1 ENSMUSG00000037070 0.0241933715424143 0.0725801146272428 0.120545895661627 0.180818843492441 0.576973746230334 0.576973746230334
Srrm2 ENSMUSG00000039218 0.254414773803597 0.381622160705395 0.00768144932639892 0.0230443479791968 0.514934023620345 0.514934023620345
Hnrnpu ENSMUSG00000039630 0.299349060054895 0.449023590082343 0.0723789610264069 0.217136883079221 0.711650020253571 0.711650020253571
Elavl1 ENSMUSG00000040028 0.00289311433957183 0.00867934301871548 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Hnrnph2 ENSMUSG00000045427 0.0325051220296005 0.0501881847305735 0.0334587898203823 0.0501881847305735 0.853801250889739 0.853801250889739
Prpf40a ENSMUSG00000061136 0.0075577836449293 0.0226733509347879 0.142165951159432 0.213248926739148 0.710208797518812 0.710208797518812
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.342026805366747 0.589478067522039 0.392985378348026 0.589478067522039 0.642864324224729 0.642864324224729
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Ddx42 ENSMUSG00000020705 0.0761127945805735 0.228338383741721 0.211844580334808 0.317766870502212 0.513026869856283 0.513026869856283
Eftud2 ENSMUSG00000020929 0.0953125666339397 0.285937699901819 0.852940894477647 0.852940894477647 0.779888212132595 0.852940894477647
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Ddx46 ENSMUSG00000021500 0.00412583181225651 0.0123774954367695 0.041737700208629 0.0626065503129434 0.252545530864481 0.252545530864481
Cwc27 ENSMUSG00000021715 0.0592616003460512 0.0888924005190768 0.000819575681707138 0.00245872704512142 0.297095062262363 0.297095062262363
Nup155 ENSMUSG00000022142 0.00683713071940991 0.0205113921582297 0.392243127063687 0.588364690595531 0.643359829732651 0.643359829732651
Fyttd1 ENSMUSG00000022800 0.0741204440774081 0.222361332232224 0.711650020253571 0.711650020253571 0.398108175780842 0.597162263671263
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Sf1 ENSMUSG00000024949 0.578113371816017 0.643359829732651 0.0756145297453648 0.226843589236094 0.643359829732651 0.643359829732651
Nup35 ENSMUSG00000026999 0.0566379395854603 0.169913818756381 0.400265374208515 0.400265374208515 0.398108175780842 0.400265374208515
Cwc22 ENSMUSG00000027014 0.214764523938594 0.322146785907891 0.0763619660358787 0.229085898107636 0.454942951775341 0.454942951775341
Ybx1 ENSMUSG00000028639 0.852940894477647 0.852940894477647 0.0953125666339397 0.285937699901819 0.5155648232968 0.7733472349452
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Gpkow ENSMUSG00000031148 0.0761127945805736 0.228338383741721 0.453225835454266 0.45596561163947 0.45596561163947 0.45596561163947
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Rbmxl1 ENSMUSG00000037070 0.0241933715424143 0.0725801146272428 0.120545895661627 0.180818843492441 0.576973746230334 0.576973746230334
Srrm2 ENSMUSG00000039218 0.254414773803597 0.381622160705395 0.00768144932639892 0.0230443479791968 0.514934023620345 0.514934023620345
Hnrnpu ENSMUSG00000039630 0.299349060054895 0.449023590082343 0.0723789610264069 0.217136883079221 0.711650020253571 0.711650020253571
Elavl1 ENSMUSG00000040028 0.00289311433957183 0.00867934301871548 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Hnrnph2 ENSMUSG00000045427 0.0325051220296005 0.0501881847305735 0.0334587898203823 0.0501881847305735 0.853801250889739 0.853801250889739
Prpf40a ENSMUSG00000061136 0.0075577836449293 0.0226733509347879 0.142165951159432 0.213248926739148 0.710208797518812 0.710208797518812
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951

SUMO E3 ligases SUMOylate target proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ikbkg ENSMUSG00000004221 0.0073134885581712 0.0219404656745136 0.146141353215796 0.219212029823693 0.641867098978198 0.641867098978198
Mta1 ENSMUSG00000021144 0.255901190956604 0.383851786434906 0.058823267388015 0.176469802164045 0.578113371816017 0.578113371816017
Nup155 ENSMUSG00000022142 0.00683713071940991 0.0205113921582297 0.392243127063687 0.588364690595531 0.643359829732651 0.643359829732651
Smc3 ENSMUSG00000024974 0.0575107614292585 0.0862661421438878 0.0436072256433733 0.0862661421438878 0.711854160331342 0.711854160331342
Stag2 ENSMUSG00000025862 0.255901190956604 0.383851786434905 0.214764523938594 0.383851786434905 0.926333123228344 0.926333123228344
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Nup35 ENSMUSG00000026999 0.0566379395854603 0.169913818756381 0.400265374208515 0.400265374208515 0.398108175780842 0.400265374208515
Casp8ap2 ENSMUSG00000028282 0.211844580334808 0.513026869856283 0.348008842235184 0.513026869856283 0.513026869856283 0.513026869856283
Blm ENSMUSG00000030528 0.180293335960318 0.270440003940477 0.096425230538547 0.270440003940477 0.711650020253571 0.711650020253571
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Smc1a ENSMUSG00000041133 0.058823267388015 0.0882349010820225 0.0588232673880149 0.0882349010820225 0.711240436189781 0.711240436189781
Mkl1 ENSMUSG00000042292 0.254414773803597 0.348008842235184 0.0741204440774082 0.222361332232225 0.348008842235184 0.348008842235184
Ikbke ENSMUSG00000042349 0.212942741031873 0.254041925545275 0.254041925545275 0.254041925545275 0.109793509122179 0.254041925545275
Nr1h4 ENSMUSG00000047638 0.148115998140416 0.222173997210623 0.294820734456232 0.294820734456232 0.091411676944639 0.222173997210623
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Top1 ENSMUSG00000070544 0.0334587898203823 0.100376369461147 0.209636747299872 0.314455120949809 0.711650020253571 0.711650020253571
Hist2h4 ENSMUSG00000091405 0.642366752097095 0.853694531487825 0.450794830295118 0.853694531487825 0.853694531487825 0.853694531487825
Zfp131 ENSMUSG00000094870 0.0315593554855452 0.0946780664566355 0.174692232033629 0.174692232033629 0.148772260628989 0.174692232033629

SUMOylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ikbkg ENSMUSG00000004221 0.0073134885581712 0.0219404656745136 0.146141353215796 0.219212029823693 0.641867098978198 0.641867098978198
Mta1 ENSMUSG00000021144 0.255901190956604 0.383851786434906 0.058823267388015 0.176469802164045 0.578113371816017 0.578113371816017
Nup155 ENSMUSG00000022142 0.00683713071940991 0.0205113921582297 0.392243127063687 0.588364690595531 0.643359829732651 0.643359829732651
Smc3 ENSMUSG00000024974 0.0575107614292585 0.0862661421438878 0.0436072256433733 0.0862661421438878 0.711854160331342 0.711854160331342
Stag2 ENSMUSG00000025862 0.255901190956604 0.383851786434905 0.214764523938594 0.383851786434905 0.926333123228344 0.926333123228344
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Nup35 ENSMUSG00000026999 0.0566379395854603 0.169913818756381 0.400265374208515 0.400265374208515 0.398108175780842 0.400265374208515
Casp8ap2 ENSMUSG00000028282 0.211844580334808 0.513026869856283 0.348008842235184 0.513026869856283 0.513026869856283 0.513026869856283
Blm ENSMUSG00000030528 0.180293335960318 0.270440003940477 0.096425230538547 0.270440003940477 0.711650020253571 0.711650020253571
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Smc1a ENSMUSG00000041133 0.058823267388015 0.0882349010820225 0.0588232673880149 0.0882349010820225 0.711240436189781 0.711240436189781
Mkl1 ENSMUSG00000042292 0.254414773803597 0.348008842235184 0.0741204440774082 0.222361332232225 0.348008842235184 0.348008842235184
Ikbke ENSMUSG00000042349 0.212942741031873 0.254041925545275 0.254041925545275 0.254041925545275 0.109793509122179 0.254041925545275
Nr1h4 ENSMUSG00000047638 0.148115998140416 0.222173997210623 0.294820734456232 0.294820734456232 0.091411676944639 0.222173997210623
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Top1 ENSMUSG00000070544 0.0334587898203823 0.100376369461147 0.209636747299872 0.314455120949809 0.711650020253571 0.711650020253571
Hist2h4 ENSMUSG00000091405 0.642366752097095 0.853694531487825 0.450794830295118 0.853694531487825 0.853694531487825 0.853694531487825
Zfp131 ENSMUSG00000094870 0.0315593554855452 0.0946780664566355 0.174692232033629 0.174692232033629 0.148772260628989 0.174692232033629

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnrnpd ENSMUSG00000000568 0.342026805366747 0.589478067522039 0.392985378348026 0.589478067522039 0.642864324224729 0.642864324224729
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Khsrp ENSMUSG00000007670 0.338976281569376 0.455625354715448 0.0432318933800775 0.129695680140232 0.455625354715448 0.455625354715448
Snrpd3 ENSMUSG00000020180 0.254787123615605 0.400265374208515 0.346899083932133 0.400265374208515 0.400265374208515 0.400265374208515
Ddx42 ENSMUSG00000020705 0.0761127945805735 0.228338383741721 0.211844580334808 0.317766870502212 0.513026869856283 0.513026869856283
Psmc5 ENSMUSG00000020708 0.399548817627028 0.399548817627028 0.29252580908486 0.399548817627028 0.399548817627028 0.399548817627028
Eftud2 ENSMUSG00000020929 0.0953125666339397 0.285937699901819 0.852940894477647 0.852940894477647 0.779888212132595 0.852940894477647
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Ddx46 ENSMUSG00000021500 0.00412583181225651 0.0123774954367695 0.041737700208629 0.0626065503129434 0.252545530864481 0.252545530864481
Cwc27 ENSMUSG00000021715 0.0592616003460512 0.0888924005190768 0.000819575681707138 0.00245872704512142 0.297095062262363 0.297095062262363
Nup155 ENSMUSG00000022142 0.00683713071940991 0.0205113921582297 0.392243127063687 0.588364690595531 0.643359829732651 0.643359829732651
Fyttd1 ENSMUSG00000022800 0.0741204440774081 0.222361332232224 0.711650020253571 0.711650020253571 0.398108175780842 0.597162263671263
Wdr33 ENSMUSG00000024400 0.00719286546902974 0.0215785964070892 0.0436072256433733 0.0654108384650599 0.255530331334266 0.255530331334266
Sf1 ENSMUSG00000024949 0.578113371816017 0.643359829732651 0.0756145297453648 0.226843589236094 0.643359829732651 0.643359829732651
Ncl ENSMUSG00000026234 0.0451153644990944 0.0882349010820225 0.058823267388015 0.0882349010820225 0.853801250889739 0.853801250889739
Nup35 ENSMUSG00000026999 0.0566379395854603 0.169913818756381 0.400265374208515 0.400265374208515 0.398108175780842 0.400265374208515
Cwc22 ENSMUSG00000027014 0.214764523938594 0.322146785907891 0.0763619660358787 0.229085898107636 0.454942951775341 0.454942951775341
Ybx1 ENSMUSG00000028639 0.852940894477647 0.852940894477647 0.0953125666339397 0.285937699901819 0.5155648232968 0.7733472349452
Fip1l1 ENSMUSG00000029227 0.171503747555202 0.378818296296722 0.252545530864481 0.378818296296722 0.711240436189781 0.711240436189781
Gpkow ENSMUSG00000031148 0.0761127945805736 0.228338383741721 0.453225835454266 0.45596561163947 0.45596561163947 0.45596561163947
Cstf2 ENSMUSG00000031256 0.0166824765447319 0.0500474296341957 0.853372965654504 0.853694531487825 0.853694531487825 0.853694531487825
Psmb10 ENSMUSG00000031897 0.511742979522636 0.771451162979439 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501
Anp32a ENSMUSG00000032249 0.0958690133561599 0.223158390943484 0.148772260628989 0.223158390943484 0.92622377157404 0.92622377157404
Dis3 ENSMUSG00000033166 0.253294730253594 0.597162263671263 0.398108175780842 0.597162263671263 0.711240436189781 0.711240436189781
Exosc4 ENSMUSG00000034259 0.058823267388015 0.176469802164045 0.214764523938594 0.322146785907891 0.853801250889739 0.853801250889739
Exosc1 ENSMUSG00000034321 0.255530331334266 0.383295497001398 0.216214347033995 0.383295497001398 0.643853282854191 0.643853282854191
Zcchc11 ENSMUSG00000034610 0.179945789077371 0.269918683616057 0.178901132102685 0.269918683616057 0.642366752097095 0.642366752097095
Cnot6l ENSMUSG00000034724 0.0969812105731562 0.290943631719469 0.642366752097095 0.642366752097095 0.640861491578951 0.642366752097095
Cpsf7 ENSMUSG00000034820 0.578113371816017 0.867170057724026 0.346527959006435 0.867170057724026 0.926658283600152 0.926658283600152
Utp6 ENSMUSG00000035575 0.0164739112492867 0.0494217337478602 0.119936171404379 0.119936171404379 0.0579478375430679 0.0869217563146018
Cnot3 ENSMUSG00000035632 0.578113371816017 0.853694531487825 0.256271555563966 0.768814666691898 0.853694531487825 0.853694531487825
Rbmxl1 ENSMUSG00000037070 0.0241933715424143 0.0725801146272428 0.120545895661627 0.180818843492441 0.576973746230334 0.576973746230334
Tsr1 ENSMUSG00000038335 0.044926265292481 0.0888924005190769 0.0592616003460512 0.0888924005190769 1 1
Srrm2 ENSMUSG00000039218 0.254414773803597 0.381622160705395 0.00768144932639892 0.0230443479791968 0.514934023620345 0.514934023620345
Hnrnpu ENSMUSG00000039630 0.299349060054895 0.449023590082343 0.0723789610264069 0.217136883079221 0.711650020253571 0.711650020253571
Elavl1 ENSMUSG00000040028 0.00289311433957183 0.00867934301871548 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152
Pcf11 ENSMUSG00000041328 0.00283103937188883 0.00849311811566649 0.211844580334808 0.317766870502212 0.511097249598474 0.511097249598474
Dcp1b ENSMUSG00000041477 0.577259514257969 0.78148726569172 0.78148726569172 0.78148726569172 0.513026869856283 0.78148726569172
Hnrnph2 ENSMUSG00000045427 0.0325051220296005 0.0501881847305735 0.0334587898203823 0.0501881847305735 0.853801250889739 0.853801250889739
Gemin6 ENSMUSG00000055760 0.452880492349546 0.7733472349452 0.5155648232968 0.7733472349452 0.852832278580641 0.852832278580641
Prpf40a ENSMUSG00000061136 0.0075577836449293 0.0226733509347879 0.142165951159432 0.213248926739148 0.710208797518812 0.710208797518812
Utp14a ENSMUSG00000063785 0.0753654386865987 0.132930357824122 0.0886202385494147 0.132930357824122 0.21549027811633 0.21549027811633
Utp3 ENSMUSG00000070697 0.0334587898203823 0.100376369461147 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Gspt2 ENSMUSG00000071723 0.148115998140416 0.444347994421247 0.782117202022501 0.782117202022501 0.711650020253571 0.782117202022501
Casc3 ENSMUSG00000078676 0.573498913947369 0.640861491578951 0.446194239410717 0.640861491578951 0.640861491578951 0.640861491578951

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sp1 ENSMUSG00000001280 0.211110344399808 0.316665516599712 0.144820068500793 0.316665516599712 0.338592117141989 0.338592117141989
Kmt2a ENSMUSG00000002028 0.0763619660358785 0.220200812784373 0.146800541856249 0.220200812784373 0.926550375688041 0.926550375688041
Polr2e ENSMUSG00000004667 0.643853282854191 0.710416009055326 0.144820068500793 0.43446020550238 0.710416009055326 0.710416009055326
Ctcf ENSMUSG00000005698 0.345037391052887 0.51755608657933 0.0964252305385472 0.289275691615642 1 1
Nr2c1 ENSMUSG00000005897 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191 0.642864324224729 0.643853282854191
Kmt2b ENSMUSG00000006307 0.853372965654504 0.853372965654504 0.0221230395928304 0.0663691187784912 0.514934023620345 0.772401035430518
Arid1a ENSMUSG00000007880 0.511097249598474 0.514934023620345 0.0753654386865988 0.226096316059796 0.514934023620345 0.514934023620345
Smurf2 ENSMUSG00000018363 0.253294730253594 0.759884190760783 0.853801250889739 0.853801250889739 0.711240436189781 0.853801250889739
Psmc5 ENSMUSG00000020708 0.399548817627028 0.399548817627028 0.29252580908486 0.399548817627028 0.399548817627028 0.399548817627028
Polr2h ENSMUSG00000021018 0.779888212132595 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
A530054K11Rik ENSMUSG00000021510 0.00768144932639892 0.0230443479791968 0.105759219123976 0.158638828685963 0.297848640636702 0.297848640636702
Plk2 ENSMUSG00000021701 0.78180291566155 0.78180291566155 0.513665062682276 0.770497594023414 0.398108175780842 0.770497594023414
Zfp871 ENSMUSG00000024298 0.0104326641569827 0.0312979924709482 0.0741204440774082 0.111180666116112 1 1
Banp ENSMUSG00000025316 0.400265374208515 0.600398061312773 0.0969812105731562 0.290943631719469 0.782117202022501 0.782117202022501
Tfap2b ENSMUSG00000025927 0.45149265530335 0.45149265530335 0.023931046492469 0.071793139477407 0.298974794311434 0.448462191467151
Esrrg ENSMUSG00000026610 0.0766111619812296 0.229833485943689 0.21549027811633 0.323235417174495 0.853480389728993 0.853480389728993
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Ccne2 ENSMUSG00000028212 0.171859370212435 0.399548817627028 0.399548817627028 0.399548817627028 0.299349060054895 0.399548817627028
Kmt2e ENSMUSG00000029004 0.255530331334265 0.383295497001398 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513
Nelfa ENSMUSG00000029111 0.455625354715449 0.710416009055326 0.710416009055326 0.710416009055326 0.578113371816017 0.710416009055326
Zkscan1 ENSMUSG00000029729 0.000747579742686132 0.00224273922805839 0.455625354715449 0.643853282854191 0.643853282854191 0.643853282854191
Zfp108 ENSMUSG00000030486 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026 0.255530331334266 0.766590994002797
Blm ENSMUSG00000030528 0.180293335960318 0.270440003940477 0.096425230538547 0.270440003940477 0.711650020253571 0.711650020253571
Wrn ENSMUSG00000031583 0.214037080764326 0.445642593393544 0.297095062262363 0.445642593393544 0.513026869856283 0.513026869856283
Brd7 ENSMUSG00000031660 0.511742979522635 0.643359829732651 0.174692232033629 0.524076696100888 0.643359829732651 0.643359829732651
Psmb10 ENSMUSG00000031897 0.511742979522636 0.771451162979439 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501
Maml2 ENSMUSG00000031925 0.343160411648939 0.514740617473408 0.0323469380768478 0.0970408142305435 0.853587578053106 0.853587578053106
Pin1 ENSMUSG00000032171 0.779238691542963 0.779238691542963 0.0761127945805736 0.228338383741721 0.454600801949285 0.681901202923927
Rnf111 ENSMUSG00000032217 0.0238002551499929 0.0714007654499788 0.254414773803597 0.381622160705395 0.711854160331342 0.711854160331342
Tcf12 ENSMUSG00000032228 0.853801250889739 0.853801250889739 0.0592616003460512 0.177784801038154 0.852940894477647 0.853801250889739
Zfp551 ENSMUSG00000034071 0.45596561163947 0.45596561163947 0.254414773803596 0.450143880930327 0.300095920620218 0.450143880930327
Med13 ENSMUSG00000034297 0.0306217702495172 0.0654108384650599 0.0436072256433733 0.0654108384650599 0.399548817627028 0.399548817627028
Cnot6l ENSMUSG00000034724 0.0969812105731562 0.290943631719469 0.642366752097095 0.642366752097095 0.640861491578951 0.642366752097095
Cnot3 ENSMUSG00000035632 0.578113371816017 0.853694531487825 0.256271555563966 0.768814666691898 0.853694531487825 0.853694531487825
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Rmi2 ENSMUSG00000037991 0.85326530496423 0.85326530496423 0.00683713071940993 0.0205113921582298 0.576687400573867 0.85326530496423
Setd1b ENSMUSG00000038384 0.0969812105731562 0.290943631719469 0.211110344399808 0.316665516599712 0.577829325134931 0.577829325134931
Taf4a ENSMUSG00000039117 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.643853282854191 0.643853282854191
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Cdk6 ENSMUSG00000040274 0.711034989117171 0.711034989117171 0.0577292451600847 0.173187735480254 0.643112334413352 0.711034989117171
Cdk13 ENSMUSG00000041297 0.00463747559282086 0.0139124267784626 0.343537039781257 0.515305559671886 0.781170242226513 0.781170242226513
Pbrm1 ENSMUSG00000042323 0.347639524025037 0.782117202022501 0.782117202022501 0.782117202022501 0.78180291566155 0.782117202022501
Nr1h4 ENSMUSG00000047638 0.148115998140416 0.222173997210623 0.294820734456232 0.294820734456232 0.091411676944639 0.222173997210623
Kmt2d ENSMUSG00000048154 0.0919695072173337 0.181275797044394 0.120850531362929 0.181275797044394 0.578396848531894 0.578396848531894
Maml1 ENSMUSG00000050567 0.395928178642446 0.395928178642446 0.346527959006435 0.395928178642446 0.346899083932133 0.395928178642446
Prkaa1 ENSMUSG00000050697 0.0753654386865988 0.226096316059796 0.711650020253571 0.926658283600152 0.926658283600152 0.926658283600152
Taf7 ENSMUSG00000051316 0.0168921052924602 0.0506763158773805 0.455625354715449 0.455625354715449 0.454942951775342 0.455625354715449
Zfp961 ENSMUSG00000052446 0.18064054691103 0.447899954960299 0.298599969973533 0.447899954960299 0.578396848531894 0.578396848531894
Mdm4 ENSMUSG00000054387 0.00463747559282086 0.0139124267784626 0.116265430850263 0.174398146275395 0.926333123228344 0.926333123228344
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Zfp78 ENSMUSG00000055150 0.17924968721805 0.537749061654149 0.926333123228344 0.926333123228344 0.455625354715449 0.683438032073173
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Rsl1 ENSMUSG00000058900 0.0315593554855452 0.0946780664566356 0.5155648232968 0.5155648232968 0.455625354715449 0.5155648232968
Zfp74 ENSMUSG00000059975 0.12935516793705 0.213248926739148 0.142165951159432 0.213248926739148 0.438516479093275 0.438516479093275
Zfp27 ENSMUSG00000062040 0.0447373296833729 0.0671059945250594 0.0445485589872461 0.0671059945250594 0.778747761033626 0.778747761033626
Brpf3 ENSMUSG00000063952 0.511097249598474 0.766645874397711 0.0321889748775514 0.0965669246326542 0.85117361048289 0.85117361048289
Zfp442 ENSMUSG00000068130 0.256271555563966 0.509798138101151 0.509798138101151 0.509798138101151 0.454600801949285 0.509798138101151
Zfp558 ENSMUSG00000074500 0.174692232033629 0.443371678590541 0.295581119060361 0.443371678590541 0.926550375688041 0.926550375688041
5830428H23Rik ENSMUSG00000074733 0.578396848531894 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Med12 ENSMUSG00000079487 0.514934023620345 0.5155648232968 0.0753654386865988 0.226096316059796 0.5155648232968 0.5155648232968
Zfp882 ENSMUSG00000089857 0.0168921052924602 0.0506763158773805 0.148115998140416 0.222173997210623 0.347639524025037 0.347639524025037
Hist2h4 ENSMUSG00000091405 0.642366752097095 0.853694531487825 0.450794830295118 0.853694531487825 0.853694531487825 0.853694531487825

SUMOylation of transcription cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmi1 ENSMUSG00000026739 0.0211129141819614 0.0316693712729421 0.0158546704257246 0.0316693712729421 0.643359829732651 0.643359829732651
Casp8ap2 ENSMUSG00000028282 0.211844580334808 0.513026869856283 0.348008842235184 0.513026869856283 0.513026869856283 0.513026869856283
Phc3 ENSMUSG00000037652 0.0315593554855452 0.0946780664566356 0.343537039781257 0.515305559671886 0.853801250889739 0.853801250889739
Cbx4 ENSMUSG00000039989 0.708534948098331 0.711034989117171 0.148115998140416 0.444347994421247 0.711034989117171 0.711034989117171
Mkl1 ENSMUSG00000042292 0.254414773803597 0.348008842235184 0.0741204440774082 0.222361332232225 0.348008842235184 0.348008842235184
Ep300 ENSMUSG00000055024 0.118409250205154 0.222173997210623 0.148115998140416 0.222173997210623 0.926333123228344 0.926333123228344
Npm1 ENSMUSG00000057113 0.148115998140416 0.444347994421247 0.576112968612194 0.707899741868332 0.707899741868332 0.707899741868332
Zfp131 ENSMUSG00000094870 0.0315593554855452 0.0946780664566355 0.174692232033629 0.174692232033629 0.148772260628989 0.174692232033629

Cohesin Loading onto Chromatin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nipbl ENSMUSG00000022141 0.0232795908282424 0.0698387724847271 0.0763619660358786 0.114542949053818 0.853907737111068 0.853907737111068
Smc3 ENSMUSG00000024974 0.0575107614292585 0.0862661421438878 0.0436072256433733 0.0862661421438878 0.711854160331342 0.711854160331342
Stag2 ENSMUSG00000025862 0.255901190956604 0.383851786434905 0.214764523938594 0.383851786434905 0.926333123228344 0.926333123228344
Smc1a ENSMUSG00000041133 0.058823267388015 0.0882349010820225 0.0588232673880149 0.0882349010820225 0.711240436189781 0.711240436189781

bisque2

RNA transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ranbp2 ENSMUSG00000003226 0.00286197841113335 0.00858593523340005 0.177153312234059 0.265729968351089 0.455625354715449 0.455625354715449
Eif2b2 ENSMUSG00000004788 0.711650020253571 0.78180291566155 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155
Phax ENSMUSG00000008301 0.0103546374915853 0.0310639124747558 0.180293335960318 0.270440003940477 1 1
Trnt1 ENSMUSG00000013736 0.711854160331342 0.926658283600152 0.853694531487825 0.926658283600152 0.926658283600152 0.926658283600152
Eif2s1 ENSMUSG00000021116 0.00276975149305653 0.00830925447916958 1 1 0.5155648232968 0.7733472349452
Eif3e ENSMUSG00000022336 0.5155648232968 0.711240436189781 0.643359829732651 0.711240436189781 0.711240436189781 0.711240436189781
Eif4a2 ENSMUSG00000022884 0.345037391052887 0.772401035430517 0.514934023620345 0.772401035430517 0.926550375688041 0.926550375688041
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Eif5b ENSMUSG00000026083 5.46967066778586e-05 0.000164090120033576 1 1 0.148115998140415 0.222173997210623
Eif3j1 ENSMUSG00000027236 0.446194239410717 0.669291359116075 0.852940894477647 0.852940894477647 0.338976281569376 0.669291359116075
Fxr1 ENSMUSG00000027680 0.0115535350288052 0.0346606050864155 0.7802108304765 0.926441990075769 0.926441990075769 0.926441990075769
Nmd3 ENSMUSG00000027787 0.0443599545252852 0.133079863575856 0.297095062262362 0.445642593393544 0.514300775319626 0.514300775319626
Eif4e ENSMUSG00000028156 0.0109864933352154 0.0329594800056461 1 1 0.643853282854191 0.965779924281287
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Magohb ENSMUSG00000030188 0.118714930081337 0.35614479024401 0.92622377157404 0.926333123228344 0.926333123228344 0.926333123228344
Eif2s3x ENSMUSG00000035150 5.62387620362729e-05 0.000168716286108819 0.121155015244363 0.181732522866545 0.513026869856283 0.513026869856283
Eif2s2 ENSMUSG00000074656 0.0451153644990945 0.135346093497283 0.7802108304765 0.7802108304765 0.710208797518812 0.7802108304765
Rasl2-9 ENSMUSG00000083649 0.255530331334266 0.521459286037555 0.577544706586058 0.577544706586058 0.347639524025037 0.521459286037555

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Eif2b2 ENSMUSG00000004788 0.711650020253571 0.78180291566155 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155
Zfp790 ENSMUSG00000011427 0.000844544805216502 0.00253363441564951 0.513665062682276 0.770497594023414 0.853480389728993 0.853480389728993
Ppp1cb ENSMUSG00000014956 0.00683713071940992 0.0205113921582298 0.642366752097095 0.642366752097095 0.297848640636702 0.446772960955053
Tbk1 ENSMUSG00000020115 0.0166824765447319 0.0500474296341958 0.577259514257969 0.577259514257969 0.255901190956604 0.383851786434906
Zfp354b ENSMUSG00000020335 0.249528554620971 0.374292831931456 0.0693988029824256 0.208196408947277 0.514300775319626 0.514300775319626
Eif2s1 ENSMUSG00000021116 0.00276975149305653 0.00830925447916958 1 1 0.5155648232968 0.7733472349452
Tmem173 ENSMUSG00000024349 5.78125466309114e-05 0.000173437639892734 0.0334587898203823 0.0501881847305735 0.853907737111068 0.853907737111068
Pik3ca ENSMUSG00000027665 0.00463747559282087 0.0139124267784626 0.283134662157423 0.424701993236134 1 1
Zfp37 ENSMUSG00000028389 0.0449262652924809 0.134778795877443 0.641867098978198 0.641867098978198 0.345037391052887 0.51755608657933
Zfp719 ENSMUSG00000030469 0.0150443553124285 0.0451330659372855 0.7802108304765 0.7802108304765 0.711034989117171 0.7802108304765
D3Ertd254e ENSMUSG00000033883 0.0331400397096515 0.0994201191289544 0.850380130396972 0.850380130396972 0.575536202757516 0.850380130396972
Zfp707 ENSMUSG00000034429 0.00755778364492931 0.0226733509347879 1 1 0.78180291566155 1
Zfp597 ENSMUSG00000039789 0.000387171985540247 0.00116151595662074 0.643853282854191 0.643853282854191 0.297095062262363 0.445642593393545
Zfp688 ENSMUSG00000045251 0.398108175780842 0.925669613555092 0.643853282854191 0.925669613555092 0.925669613555092 0.925669613555092
Zfp235 ENSMUSG00000047603 0.0741204440774081 0.222361332232224 0.926658283600152 0.926658283600152 0.513665062682276 0.770497594023414
Zfp52 ENSMUSG00000051341 0.0241933715424143 0.0725801146272428 0.85117361048289 0.924987846321933 0.924987846321933 0.924987846321933
Zfp667 ENSMUSG00000054893 0.043419472370771 0.130258417112313 0.393724994268831 0.590587491403246 0.853372965654504 0.853372965654504
Zfp458 ENSMUSG00000055480 0.00743512899358789 0.0223053869807637 0.214764523938594 0.299349060054895 0.299349060054895 0.299349060054895
A430033K04Rik ENSMUSG00000056014 0.010906560635693 0.032719681907079 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739
Zfp709 ENSMUSG00000056019 0.215127611919161 0.643606811957488 0.642117186565222 0.643606811957488 0.643606811957488 0.643606811957488
Zfp426 ENSMUSG00000059475 0.0109864933352154 0.0329594800056461 0.852940894477647 0.926441990075769 0.926441990075769 0.926441990075769
Zfp874b ENSMUSG00000059839 0.120850531362929 0.362551594088788 0.7802108304765 0.781170242226513 0.781170242226513 0.781170242226513
Zfp941 ENSMUSG00000060314 0.0334587898203824 0.100376369461147 0.180293335960318 0.270440003940477 0.643359829732651 0.643359829732651
Zfp868 ENSMUSG00000060427 0.347639524025037 0.853372965654504 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Cycs ENSMUSG00000063694 0.0746183450292887 0.223855035087866 0.711854160331342 0.711854160331342 0.643359829732651 0.711854160331342
Zfp763 ENSMUSG00000067430 0.0592616003460512 0.177784801038154 0.297848640636702 0.446772960955053 0.710208797518812 0.710208797518812
Zfp948 ENSMUSG00000067931 0.148115998140415 0.444347994421246 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Zfp874a ENSMUSG00000069206 0.0328221470541517 0.098466441162455 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Zfp712 ENSMUSG00000090641 0.0331400397096515 0.0994201191289544 0.392985378348026 0.573498913947369 0.573498913947369 0.573498913947369
Gm4767 ENSMUSG00000094076 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Gm10778 ENSMUSG00000096856 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593

Protein processing in endoplasmic reticulum

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Derl2 ENSMUSG00000018442 0.0753654386865987 0.226096316059796 0.926550375688041 0.926550375688041 0.852940894477647 0.926550375688041
Hsp90b1 ENSMUSG00000020048 0.0325051220296004 0.0975153660888012 0.346527959006435 0.519791938509652 0.640355507848752 0.640355507848752
Pdia6 ENSMUSG00000020571 0.0115535350288052 0.0346606050864156 0.710208797518812 0.710208797518812 0.452880492349546 0.679320738524319
Eif2s1 ENSMUSG00000021116 0.00276975149305653 0.00830925447916958 1 1 0.5155648232968 0.7733472349452
Hsp90aa1 ENSMUSG00000021270 0.0964252305385472 0.289275691615642 0.853372965654504 1 1 1
Ero1l ENSMUSG00000021831 0.000819575681707138 0.00245872704512142 0.0969812105731562 0.145471815859734 1 1
Dnajc3 ENSMUSG00000022136 0.00264953297731414 0.00794859893194242 0.707899741868332 0.710001140920767 0.710001140920767 0.710001140920767
Hspa5 ENSMUSG00000026864 0.00283103937188884 0.00849311811566652 0.399548817627028 0.599323226440542 1 1
Dnajc10 ENSMUSG00000027006 0.211110344399808 0.633331033199424 0.452880492349546 0.679320738524319 0.711854160331342 0.711854160331342
Sec62 ENSMUSG00000027706 0.0449262652924809 0.134778795877443 0.642366752097095 0.642366752097095 0.513026869856283 0.642366752097095
Dnaja1 ENSMUSG00000028410 0.00481536616919078 0.0144460985075723 1 1 0.643359829732651 0.965039744598977
Plaa ENSMUSG00000028577 0.0441715176243983 0.132514552873195 0.200270339336752 0.297472133192261 0.297472133192261 0.297472133192261
Stt3a ENSMUSG00000032116 0.00159435459956481 0.00478306379869443 0.340887582990546 0.45596561163947 0.45596561163947 0.45596561163947
Ssr2 ENSMUSG00000041355 0.214037080764326 0.374861176998506 0.514300775319626 0.514300775319626 0.249907451332337 0.374861176998506
Yod1 ENSMUSG00000046404 0.00396264524680381 0.0118879357404114 0.513346277289108 0.770019415933663 0.781960228679124 0.781960228679124
Ube2d3 ENSMUSG00000078578 0.000164597779190222 0.000493793337570665 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ranbp2 ENSMUSG00000003226 0.00286197841113335 0.00858593523340005 0.177153312234059 0.265729968351089 0.455625354715449 0.455625354715449
Zfp655 ENSMUSG00000007812 0.0008445448052165 0.0025336344156495 0.455625354715448 0.683438032073173 0.781170242226513 0.781170242226513
Phax ENSMUSG00000008301 0.0103546374915853 0.0310639124747558 0.180293335960318 0.270440003940477 1 1
Rnmt ENSMUSG00000009535 0.00768144932639892 0.0230443479791968 1 1 0.45596561163947 0.683948417459205
Zfp790 ENSMUSG00000011427 0.000844544805216502 0.00253363441564951 0.513665062682276 0.770497594023414 0.853480389728993 0.853480389728993
Cnot2 ENSMUSG00000020166 0.0109864933352154 0.0329594800056461 0.158747568220452 0.238121352330678 0.249528554620971 0.249528554620971
Zfp354b ENSMUSG00000020335 0.249528554620971 0.374292831931456 0.0693988029824256 0.208196408947277 0.514300775319626 0.514300775319626
Psmd12 ENSMUSG00000020720 0.0436072256433733 0.13082167693012 1 1 0.7802108304765 1
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Zfp839 ENSMUSG00000021271 0.119631084167592 0.358893252502775 0.78132892626786 0.78132892626786 0.78132892626786 0.78132892626786
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Psmc6 ENSMUSG00000021832 0.0449262652924809 0.134778795877443 0.852832278580641 0.852832278580641 0.577259514257969 0.852832278580641
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Nabp1 ENSMUSG00000026107 0.709375484777034 0.926003599371281 0.926003599371281 0.926003599371281 0.711650020253571 0.926003599371281
Cdc73 ENSMUSG00000026361 0.00283103937188883 0.0084931181156665 0.577829325134931 0.78180291566155 0.78180291566155 0.78180291566155
Rbbp5 ENSMUSG00000026439 0.00283103937188883 0.0084931181156665 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155
Ints12 ENSMUSG00000028016 0.0436072256433734 0.13082167693012 0.704440461749122 0.704440461749122 0.450444934184774 0.675667401277161
Nbn ENSMUSG00000028224 0.0419238354397911 0.125771506319373 1 1 0.926333123228344 1
Ccnc ENSMUSG00000028252 0.00477055016690543 0.0143116505007163 0.216214347033995 0.324321520550992 0.577829325134931 0.577829325134931
Gtf2b ENSMUSG00000028271 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Rngtt ENSMUSG00000028274 0.00481536616919075 0.0144460985075723 0.711240436189781 0.711240436189781 0.5155648232968 0.711240436189781
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Zfp37 ENSMUSG00000028389 0.0449262652924809 0.134778795877443 0.641867098978198 0.641867098978198 0.345037391052887 0.51755608657933
Snapc3 ENSMUSG00000028483 0.0228917506363373 0.068675251909012 0.575246939700399 0.575246939700399 0.452880492349546 0.575246939700399
Ago3 ENSMUSG00000028842 0.0562022152993845 0.168606645898153 0.711650020253571 0.711650020253571 0.398108175780842 0.597162263671263
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Kras ENSMUSG00000030265 0.00468160475316412 0.0140448142594924 0.345037391052887 0.514934023620344 0.514934023620344 0.514934023620344
Psmd8 ENSMUSG00000030591 0.09586901335616 0.28760704006848 0.926658283600152 0.926658283600152 0.455625354715448 0.683438032073173
Psma1 ENSMUSG00000030751 0.400265374208516 0.853801250889739 0.853480389728993 0.853801250889739 0.853801250889739 0.853801250889739
Smarca5 ENSMUSG00000031715 0.000771096743445033 0.0023132902303351 0.5155648232968 0.642864324224729 0.642864324224729 0.642864324224729
Nudt21 ENSMUSG00000031754 0.00481536616919077 0.0144460985075723 0.706616781330066 0.706616781330066 0.453570536021945 0.680355804032917
Psma4 ENSMUSG00000032301 0.255530331334266 0.766590994002797 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Tcea1 ENSMUSG00000033813 0.0236697127745139 0.0710091383235417 1 1 0.577829325134931 0.866743987702397
D3Ertd254e ENSMUSG00000033883 0.0331400397096515 0.0994201191289544 0.850380130396972 0.850380130396972 0.575536202757516 0.850380130396972
Rmi1 ENSMUSG00000035367 0.00481536616919075 0.0144460985075723 0.641867098978197 0.853801250889739 0.853801250889739 0.853801250889739
Cnot1 ENSMUSG00000036550 0.0117179415987427 0.0351538247962282 0.211110344399808 0.316665516599712 0.513026869856283 0.513026869856283
Med30 ENSMUSG00000038622 0.297848640636703 0.599323226440542 1 1 0.399548817627028 0.599323226440542
Polr3k ENSMUSG00000038628 0.216214347033995 0.648643041101984 0.514934023620345 0.711034989117171 0.711034989117171 0.711034989117171
Rabggtb ENSMUSG00000038975 0.297095062262362 0.521459286037555 0.642864324224729 0.642864324224729 0.347639524025037 0.521459286037555
Zfp770 ENSMUSG00000040321 0.0241933715424143 0.0725801146272428 0.711240436189781 1 1 1
Ints8 ENSMUSG00000040738 0.0579478375430679 0.173843512629204 0.578113371816017 0.578113371816017 0.578113371816017 0.578113371816017
Gtf3c3 ENSMUSG00000041303 0.11810342389482 0.354310271684459 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Rragb ENSMUSG00000041658 0.00283103937188882 0.00849311811566647 0.299349060054896 0.449023590082344 0.782117202022501 0.782117202022501
Zfp688 ENSMUSG00000045251 0.398108175780842 0.925669613555092 0.643853282854191 0.925669613555092 0.925669613555092 0.925669613555092
Zfp235 ENSMUSG00000047603 0.0741204440774081 0.222361332232224 0.926658283600152 0.926658283600152 0.513665062682276 0.770497594023414
Zfp738 ENSMUSG00000048280 0.0763619660358784 0.229085898107635 0.255901190956604 0.383851786434906 0.926333123228344 0.926333123228344
Bdp1 ENSMUSG00000049658 0.0746183450292888 0.138156294413154 0.138156294413154 0.138156294413154 0.110721602500731 0.138156294413154
Zfp52 ENSMUSG00000051341 0.0241933715424143 0.0725801146272428 0.85117361048289 0.924987846321933 0.924987846321933 0.924987846321933
Taf9 ENSMUSG00000052293 0.0241933715424143 0.0725801146272428 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155
Yap1 ENSMUSG00000053110 0.0761127945805735 0.22833838374172 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041
Zfp667 ENSMUSG00000054893 0.043419472370771 0.130258417112313 0.393724994268831 0.590587491403246 0.853372965654504 0.853372965654504
Zfp458 ENSMUSG00000055480 0.00743512899358789 0.0223053869807637 0.214764523938594 0.299349060054895 0.299349060054895 0.299349060054895
A430033K04Rik ENSMUSG00000056014 0.010906560635693 0.032719681907079 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739
Zfp709 ENSMUSG00000056019 0.215127611919161 0.643606811957488 0.642117186565222 0.643606811957488 0.643606811957488 0.643606811957488
Zfp426 ENSMUSG00000059475 0.0109864933352154 0.0329594800056461 0.852940894477647 0.926441990075769 0.926441990075769 0.926441990075769
Zfp874b ENSMUSG00000059839 0.120850531362929 0.362551594088788 0.7802108304765 0.781170242226513 0.781170242226513 0.781170242226513
Zfp35 ENSMUSG00000063281 0.0588232673880149 0.176469802164045 0.926550375688041 0.926550375688041 0.254414773803597 0.381622160705395
Cycs ENSMUSG00000063694 0.0746183450292887 0.223855035087866 0.711854160331342 0.711854160331342 0.643359829732651 0.711854160331342
Nupl1 ENSMUSG00000063895 0.00270924971713393 0.00812774915140178 0.146800541856249 0.220200812784373 0.92589277149125 0.92589277149125
Nr6a1 ENSMUSG00000063972 0.0743693776059065 0.223108132817719 0.78180291566155 0.78180291566155 0.7802108304765 0.78180291566155
Polr1c ENSMUSG00000067148 0.0162664168407233 0.0487992505221699 0.255530331334266 0.255530331334266 0.0331400397096515 0.0497100595644773
Zfp763 ENSMUSG00000067430 0.0592616003460512 0.177784801038154 0.297848640636702 0.446772960955053 0.710208797518812 0.710208797518812
Zfp948 ENSMUSG00000067931 0.148115998140415 0.444347994421246 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961
Zfp874a ENSMUSG00000069206 0.0328221470541517 0.098466441162455 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Rslcan18 ENSMUSG00000074824 0.0766111619812293 0.229833485943688 0.455625354715449 0.683438032073173 0.853694531487825 0.853694531487825
Ube2d3 ENSMUSG00000078578 0.000164597779190222 0.000493793337570665 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501
Taf9 ENSMUSG00000078941 0.299349060054895 0.709375484777034 0.709375484777034 0.709375484777034 0.642366752097095 0.709375484777034
Gm14399 ENSMUSG00000090093 0.345410946355104 0.521459286037555 0.576973746230334 0.576973746230334 0.347639524025037 0.521459286037555
2610021A01Rik ENSMUSG00000091474 0.0969812105731561 0.290943631719468 0.779888212132595 0.779888212132595 0.712057867818062 0.779888212132595
Gm4767 ENSMUSG00000094076 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Gm10778 ENSMUSG00000096856 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Zfp955b ENSMUSG00000096910 0.00153425095635555 0.00460275286906664 0.514934023620345 0.5155648232968 0.5155648232968 0.5155648232968

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp655 ENSMUSG00000007812 0.0008445448052165 0.0025336344156495 0.455625354715448 0.683438032073173 0.781170242226513 0.781170242226513
Phax ENSMUSG00000008301 0.0103546374915853 0.0310639124747558 0.180293335960318 0.270440003940477 1 1
Rnmt ENSMUSG00000009535 0.00768144932639892 0.0230443479791968 1 1 0.45596561163947 0.683948417459205
Zfp790 ENSMUSG00000011427 0.000844544805216502 0.00253363441564951 0.513665062682276 0.770497594023414 0.853480389728993 0.853480389728993
Cnot2 ENSMUSG00000020166 0.0109864933352154 0.0329594800056461 0.158747568220452 0.238121352330678 0.249528554620971 0.249528554620971
Zfp354b ENSMUSG00000020335 0.249528554620971 0.374292831931456 0.0693988029824256 0.208196408947277 0.514300775319626 0.514300775319626
Psmd12 ENSMUSG00000020720 0.0436072256433733 0.13082167693012 1 1 0.7802108304765 1
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Zfp839 ENSMUSG00000021271 0.119631084167592 0.358893252502775 0.78132892626786 0.78132892626786 0.78132892626786 0.78132892626786
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Psmc6 ENSMUSG00000021832 0.0449262652924809 0.134778795877443 0.852832278580641 0.852832278580641 0.577259514257969 0.852832278580641
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Nabp1 ENSMUSG00000026107 0.709375484777034 0.926003599371281 0.926003599371281 0.926003599371281 0.711650020253571 0.926003599371281
Cdc73 ENSMUSG00000026361 0.00283103937188883 0.0084931181156665 0.577829325134931 0.78180291566155 0.78180291566155 0.78180291566155
Rbbp5 ENSMUSG00000026439 0.00283103937188883 0.0084931181156665 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155
Ints12 ENSMUSG00000028016 0.0436072256433734 0.13082167693012 0.704440461749122 0.704440461749122 0.450444934184774 0.675667401277161
Nbn ENSMUSG00000028224 0.0419238354397911 0.125771506319373 1 1 0.926333123228344 1
Ccnc ENSMUSG00000028252 0.00477055016690543 0.0143116505007163 0.216214347033995 0.324321520550992 0.577829325134931 0.577829325134931
Gtf2b ENSMUSG00000028271 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Rngtt ENSMUSG00000028274 0.00481536616919075 0.0144460985075723 0.711240436189781 0.711240436189781 0.5155648232968 0.711240436189781
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Zfp37 ENSMUSG00000028389 0.0449262652924809 0.134778795877443 0.641867098978198 0.641867098978198 0.345037391052887 0.51755608657933
Snapc3 ENSMUSG00000028483 0.0228917506363373 0.068675251909012 0.575246939700399 0.575246939700399 0.452880492349546 0.575246939700399
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Kras ENSMUSG00000030265 0.00468160475316412 0.0140448142594924 0.345037391052887 0.514934023620344 0.514934023620344 0.514934023620344
Psmd8 ENSMUSG00000030591 0.09586901335616 0.28760704006848 0.926658283600152 0.926658283600152 0.455625354715448 0.683438032073173
Psma1 ENSMUSG00000030751 0.400265374208516 0.853801250889739 0.853480389728993 0.853801250889739 0.853801250889739 0.853801250889739
Nudt21 ENSMUSG00000031754 0.00481536616919077 0.0144460985075723 0.706616781330066 0.706616781330066 0.453570536021945 0.680355804032917
Psma4 ENSMUSG00000032301 0.255530331334266 0.766590994002797 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Tcea1 ENSMUSG00000033813 0.0236697127745139 0.0710091383235417 1 1 0.577829325134931 0.866743987702397
D3Ertd254e ENSMUSG00000033883 0.0331400397096515 0.0994201191289544 0.850380130396972 0.850380130396972 0.575536202757516 0.850380130396972
Rmi1 ENSMUSG00000035367 0.00481536616919075 0.0144460985075723 0.641867098978197 0.853801250889739 0.853801250889739 0.853801250889739
Cnot1 ENSMUSG00000036550 0.0117179415987427 0.0351538247962282 0.211110344399808 0.316665516599712 0.513026869856283 0.513026869856283
Med30 ENSMUSG00000038622 0.297848640636703 0.599323226440542 1 1 0.399548817627028 0.599323226440542
Rabggtb ENSMUSG00000038975 0.297095062262362 0.521459286037555 0.642864324224729 0.642864324224729 0.347639524025037 0.521459286037555
Zfp770 ENSMUSG00000040321 0.0241933715424143 0.0725801146272428 0.711240436189781 1 1 1
Ints8 ENSMUSG00000040738 0.0579478375430679 0.173843512629204 0.578113371816017 0.578113371816017 0.578113371816017 0.578113371816017
Rragb ENSMUSG00000041658 0.00283103937188882 0.00849311811566647 0.299349060054896 0.449023590082344 0.782117202022501 0.782117202022501
Zfp688 ENSMUSG00000045251 0.398108175780842 0.925669613555092 0.643853282854191 0.925669613555092 0.925669613555092 0.925669613555092
Zfp235 ENSMUSG00000047603 0.0741204440774081 0.222361332232224 0.926658283600152 0.926658283600152 0.513665062682276 0.770497594023414
Zfp738 ENSMUSG00000048280 0.0763619660358784 0.229085898107635 0.255901190956604 0.383851786434906 0.926333123228344 0.926333123228344
Zfp52 ENSMUSG00000051341 0.0241933715424143 0.0725801146272428 0.85117361048289 0.924987846321933 0.924987846321933 0.924987846321933
Taf9 ENSMUSG00000052293 0.0241933715424143 0.0725801146272428 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155
Yap1 ENSMUSG00000053110 0.0761127945805735 0.22833838374172 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041
Zfp667 ENSMUSG00000054893 0.043419472370771 0.130258417112313 0.393724994268831 0.590587491403246 0.853372965654504 0.853372965654504
Zfp458 ENSMUSG00000055480 0.00743512899358789 0.0223053869807637 0.214764523938594 0.299349060054895 0.299349060054895 0.299349060054895
A430033K04Rik ENSMUSG00000056014 0.010906560635693 0.032719681907079 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739
Zfp709 ENSMUSG00000056019 0.215127611919161 0.643606811957488 0.642117186565222 0.643606811957488 0.643606811957488 0.643606811957488
Zfp426 ENSMUSG00000059475 0.0109864933352154 0.0329594800056461 0.852940894477647 0.926441990075769 0.926441990075769 0.926441990075769
Zfp874b ENSMUSG00000059839 0.120850531362929 0.362551594088788 0.7802108304765 0.781170242226513 0.781170242226513 0.781170242226513
Zfp35 ENSMUSG00000063281 0.0588232673880149 0.176469802164045 0.926550375688041 0.926550375688041 0.254414773803597 0.381622160705395
Cycs ENSMUSG00000063694 0.0746183450292887 0.223855035087866 0.711854160331342 0.711854160331342 0.643359829732651 0.711854160331342
Nr6a1 ENSMUSG00000063972 0.0743693776059065 0.223108132817719 0.78180291566155 0.78180291566155 0.7802108304765 0.78180291566155
Zfp763 ENSMUSG00000067430 0.0592616003460512 0.177784801038154 0.297848640636702 0.446772960955053 0.710208797518812 0.710208797518812
Zfp948 ENSMUSG00000067931 0.148115998140415 0.444347994421246 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961
Zfp874a ENSMUSG00000069206 0.0328221470541517 0.098466441162455 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Rslcan18 ENSMUSG00000074824 0.0766111619812293 0.229833485943688 0.455625354715449 0.683438032073173 0.853694531487825 0.853694531487825
Ube2d3 ENSMUSG00000078578 0.000164597779190222 0.000493793337570665 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501
Taf9 ENSMUSG00000078941 0.299349060054895 0.709375484777034 0.709375484777034 0.709375484777034 0.642366752097095 0.709375484777034
Gm14399 ENSMUSG00000090093 0.345410946355104 0.521459286037555 0.576973746230334 0.576973746230334 0.347639524025037 0.521459286037555
2610021A01Rik ENSMUSG00000091474 0.0969812105731561 0.290943631719468 0.779888212132595 0.779888212132595 0.712057867818062 0.779888212132595
Gm4767 ENSMUSG00000094076 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Gm10778 ENSMUSG00000096856 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Zfp955b ENSMUSG00000096910 0.00153425095635555 0.00460275286906664 0.514934023620345 0.5155648232968 0.5155648232968 0.5155648232968

PERK regulates gene expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Eif2s1 ENSMUSG00000021116 0.00276975149305653 0.00830925447916958 1 1 0.5155648232968 0.7733472349452
Eif2s3x ENSMUSG00000035150 5.62387620362729e-05 0.000168716286108819 0.121155015244363 0.181732522866545 0.513026869856283 0.513026869856283
Eif2s2 ENSMUSG00000074656 0.0451153644990945 0.135346093497283 0.7802108304765 0.7802108304765 0.710208797518812 0.7802108304765

RNA polymerase II transcribes snRNA genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Phax ENSMUSG00000008301 0.0103546374915853 0.0310639124747558 0.180293335960318 0.270440003940477 1 1
Nabp1 ENSMUSG00000026107 0.709375484777034 0.926003599371281 0.926003599371281 0.926003599371281 0.711650020253571 0.926003599371281
Ints12 ENSMUSG00000028016 0.0436072256433734 0.13082167693012 0.704440461749122 0.704440461749122 0.450444934184774 0.675667401277161
Gtf2b ENSMUSG00000028271 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Snapc3 ENSMUSG00000028483 0.0228917506363373 0.068675251909012 0.575246939700399 0.575246939700399 0.452880492349546 0.575246939700399
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Ints8 ENSMUSG00000040738 0.0579478375430679 0.173843512629204 0.578113371816017 0.578113371816017 0.578113371816017 0.578113371816017
Taf9 ENSMUSG00000052293 0.0241933715424143 0.0725801146272428 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961
Taf9 ENSMUSG00000078941 0.299349060054895 0.709375484777034 0.709375484777034 0.709375484777034 0.642366752097095 0.709375484777034

mRNA Capping

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rnmt ENSMUSG00000009535 0.00768144932639892 0.0230443479791968 1 1 0.45596561163947 0.683948417459205
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Rngtt ENSMUSG00000028274 0.00481536616919075 0.0144460985075723 0.711240436189781 0.711240436189781 0.5155648232968 0.711240436189781
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961

Global Genome Nucleotide Excision Repair (GG-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Polk ENSMUSG00000021668 0.0592616003460513 0.177784801038154 0.636229315311352 0.636229315311352 0.450794830295118 0.636229315311352
Ube2v2 ENSMUSG00000022674 0.0240620856673909 0.0721862570021727 0.781170242226513 0.781170242226513 0.640861491578951 0.781170242226513
Cops5 ENSMUSG00000025917 0.255530331334266 0.766590994002797 0.708534948098331 0.778911768167544 0.778911768167544 0.778911768167544
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Cops2 ENSMUSG00000027206 0.0287722902807988 0.0863168708423963 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Cetn2 ENSMUSG00000031347 0.213307944885796 0.513026869856283 0.513026869856283 0.513026869856283 0.399548817627028 0.513026869856283
Pias1 ENSMUSG00000032405 5.46967066778586e-05 0.000164090120033576 0.853907737111068 0.853907737111068 0.299349060054895 0.449023590082343
Cops4 ENSMUSG00000035297 0.0113089139751576 0.0339267419254727 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041
Usp45 ENSMUSG00000040455 0.0566379395854603 0.169913818756381 0.926658283600152 0.926658283600152 0.454942951775341 0.682414427663012

Nucleotide Excision Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Polk ENSMUSG00000021668 0.0592616003460513 0.177784801038154 0.636229315311352 0.636229315311352 0.450794830295118 0.636229315311352
Ube2v2 ENSMUSG00000022674 0.0240620856673909 0.0721862570021727 0.781170242226513 0.781170242226513 0.640861491578951 0.781170242226513
Cops5 ENSMUSG00000025917 0.255530331334266 0.766590994002797 0.708534948098331 0.778911768167544 0.778911768167544 0.778911768167544
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Cops2 ENSMUSG00000027206 0.0287722902807988 0.0863168708423963 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Cetn2 ENSMUSG00000031347 0.213307944885796 0.513026869856283 0.513026869856283 0.513026869856283 0.399548817627028 0.513026869856283
Pias1 ENSMUSG00000032405 5.46967066778586e-05 0.000164090120033576 0.853907737111068 0.853907737111068 0.299349060054895 0.449023590082343
Tcea1 ENSMUSG00000033813 0.0236697127745139 0.0710091383235417 1 1 0.577829325134931 0.866743987702397
Cops4 ENSMUSG00000035297 0.0113089139751576 0.0339267419254727 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041
Usp45 ENSMUSG00000040455 0.0566379395854603 0.169913818756381 0.926658283600152 0.926658283600152 0.454942951775341 0.682414427663012

Recycling of eIF2:GDP

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Eif2b2 ENSMUSG00000004788 0.711650020253571 0.78180291566155 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155
Eif2s1 ENSMUSG00000021116 0.00276975149305653 0.00830925447916958 1 1 0.5155648232968 0.7733472349452
Eif2s3x ENSMUSG00000035150 5.62387620362729e-05 0.000168716286108819 0.121155015244363 0.181732522866545 0.513026869856283 0.513026869856283
Eif2s2 ENSMUSG00000074656 0.0451153644990945 0.135346093497283 0.7802108304765 0.7802108304765 0.710208797518812 0.7802108304765

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp655 ENSMUSG00000007812 0.0008445448052165 0.0025336344156495 0.455625354715448 0.683438032073173 0.781170242226513 0.781170242226513
Zfp790 ENSMUSG00000011427 0.000844544805216502 0.00253363441564951 0.513665062682276 0.770497594023414 0.853480389728993 0.853480389728993
Cnot2 ENSMUSG00000020166 0.0109864933352154 0.0329594800056461 0.158747568220452 0.238121352330678 0.249528554620971 0.249528554620971
Zfp354b ENSMUSG00000020335 0.249528554620971 0.374292831931456 0.0693988029824256 0.208196408947277 0.514300775319626 0.514300775319626
Psmd12 ENSMUSG00000020720 0.0436072256433733 0.13082167693012 1 1 0.7802108304765 1
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Zfp839 ENSMUSG00000021271 0.119631084167592 0.358893252502775 0.78132892626786 0.78132892626786 0.78132892626786 0.78132892626786
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Psmc6 ENSMUSG00000021832 0.0449262652924809 0.134778795877443 0.852832278580641 0.852832278580641 0.577259514257969 0.852832278580641
Sumo1 ENSMUSG00000026021 0.400265374208516 0.643853282854191 0.643359829732651 0.643853282854191 0.643853282854191 0.643853282854191
Rbbp5 ENSMUSG00000026439 0.00283103937188883 0.0084931181156665 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155
Nbn ENSMUSG00000028224 0.0419238354397911 0.125771506319373 1 1 0.926333123228344 1
Ccnc ENSMUSG00000028252 0.00477055016690543 0.0143116505007163 0.216214347033995 0.324321520550992 0.577829325134931 0.577829325134931
Zfp37 ENSMUSG00000028389 0.0449262652924809 0.134778795877443 0.641867098978198 0.641867098978198 0.345037391052887 0.51755608657933
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Kras ENSMUSG00000030265 0.00468160475316412 0.0140448142594924 0.345037391052887 0.514934023620344 0.514934023620344 0.514934023620344
Psmd8 ENSMUSG00000030591 0.09586901335616 0.28760704006848 0.926658283600152 0.926658283600152 0.455625354715448 0.683438032073173
Psma1 ENSMUSG00000030751 0.400265374208516 0.853801250889739 0.853480389728993 0.853801250889739 0.853801250889739 0.853801250889739
Psma4 ENSMUSG00000032301 0.255530331334266 0.766590994002797 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Tcea1 ENSMUSG00000033813 0.0236697127745139 0.0710091383235417 1 1 0.577829325134931 0.866743987702397
D3Ertd254e ENSMUSG00000033883 0.0331400397096515 0.0994201191289544 0.850380130396972 0.850380130396972 0.575536202757516 0.850380130396972
Rmi1 ENSMUSG00000035367 0.00481536616919075 0.0144460985075723 0.641867098978197 0.853801250889739 0.853801250889739 0.853801250889739
Cnot1 ENSMUSG00000036550 0.0117179415987427 0.0351538247962282 0.211110344399808 0.316665516599712 0.513026869856283 0.513026869856283
Med30 ENSMUSG00000038622 0.297848640636703 0.599323226440542 1 1 0.399548817627028 0.599323226440542
Rabggtb ENSMUSG00000038975 0.297095062262362 0.521459286037555 0.642864324224729 0.642864324224729 0.347639524025037 0.521459286037555
Zfp770 ENSMUSG00000040321 0.0241933715424143 0.0725801146272428 0.711240436189781 1 1 1
Rragb ENSMUSG00000041658 0.00283103937188882 0.00849311811566647 0.299349060054896 0.449023590082344 0.782117202022501 0.782117202022501
Zfp688 ENSMUSG00000045251 0.398108175780842 0.925669613555092 0.643853282854191 0.925669613555092 0.925669613555092 0.925669613555092
Zfp235 ENSMUSG00000047603 0.0741204440774081 0.222361332232224 0.926658283600152 0.926658283600152 0.513665062682276 0.770497594023414
Zfp738 ENSMUSG00000048280 0.0763619660358784 0.229085898107635 0.255901190956604 0.383851786434906 0.926333123228344 0.926333123228344
Zfp52 ENSMUSG00000051341 0.0241933715424143 0.0725801146272428 0.85117361048289 0.924987846321933 0.924987846321933 0.924987846321933
Taf9 ENSMUSG00000052293 0.0241933715424143 0.0725801146272428 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155
Yap1 ENSMUSG00000053110 0.0761127945805735 0.22833838374172 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041
Zfp667 ENSMUSG00000054893 0.043419472370771 0.130258417112313 0.393724994268831 0.590587491403246 0.853372965654504 0.853372965654504
Zfp458 ENSMUSG00000055480 0.00743512899358789 0.0223053869807637 0.214764523938594 0.299349060054895 0.299349060054895 0.299349060054895
A430033K04Rik ENSMUSG00000056014 0.010906560635693 0.032719681907079 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739
Zfp709 ENSMUSG00000056019 0.215127611919161 0.643606811957488 0.642117186565222 0.643606811957488 0.643606811957488 0.643606811957488
Zfp426 ENSMUSG00000059475 0.0109864933352154 0.0329594800056461 0.852940894477647 0.926441990075769 0.926441990075769 0.926441990075769
Zfp874b ENSMUSG00000059839 0.120850531362929 0.362551594088788 0.7802108304765 0.781170242226513 0.781170242226513 0.781170242226513
Zfp35 ENSMUSG00000063281 0.0588232673880149 0.176469802164045 0.926550375688041 0.926550375688041 0.254414773803597 0.381622160705395
Cycs ENSMUSG00000063694 0.0746183450292887 0.223855035087866 0.711854160331342 0.711854160331342 0.643359829732651 0.711854160331342
Nr6a1 ENSMUSG00000063972 0.0743693776059065 0.223108132817719 0.78180291566155 0.78180291566155 0.7802108304765 0.78180291566155
Zfp763 ENSMUSG00000067430 0.0592616003460512 0.177784801038154 0.297848640636702 0.446772960955053 0.710208797518812 0.710208797518812
Zfp948 ENSMUSG00000067931 0.148115998140415 0.444347994421246 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961
Zfp874a ENSMUSG00000069206 0.0328221470541517 0.098466441162455 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Rslcan18 ENSMUSG00000074824 0.0766111619812293 0.229833485943688 0.455625354715449 0.683438032073173 0.853694531487825 0.853694531487825
Ube2d3 ENSMUSG00000078578 0.000164597779190222 0.000493793337570665 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501
Taf9 ENSMUSG00000078941 0.299349060054895 0.709375484777034 0.709375484777034 0.709375484777034 0.642366752097095 0.709375484777034
Gm14399 ENSMUSG00000090093 0.345410946355104 0.521459286037555 0.576973746230334 0.576973746230334 0.347639524025037 0.521459286037555
2610021A01Rik ENSMUSG00000091474 0.0969812105731561 0.290943631719468 0.779888212132595 0.779888212132595 0.712057867818062 0.779888212132595
Gm4767 ENSMUSG00000094076 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Gm10778 ENSMUSG00000096856 0.121155015244363 0.363465045733089 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593
Zfp955b ENSMUSG00000096910 0.00153425095635555 0.00460275286906664 0.514934023620345 0.5155648232968 0.5155648232968 0.5155648232968

RNA Pol II CTD phosphorylation and interaction with CE

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rnmt ENSMUSG00000009535 0.00768144932639892 0.0230443479791968 1 1 0.45596561163947 0.683948417459205
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Rngtt ENSMUSG00000028274 0.00481536616919075 0.0144460985075723 0.711240436189781 0.711240436189781 0.5155648232968 0.711240436189781
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961

Class I peroxisomal membrane protein import

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pxmp4 ENSMUSG00000000876 0.255530331334265 0.643853282854191 0.514934023620345 0.643853282854191 0.643853282854191 0.643853282854191
Atad1 ENSMUSG00000013662 0.096981210573156 0.290943631719468 0.926441990075769 0.926441990075769 0.712057867818062 0.926441990075769
Pex3 ENSMUSG00000019809 0.298974794311434 0.448462191467151 0.120545895661628 0.361637686984883 0.709166031912266 0.709166031912266
Pex13 ENSMUSG00000020283 0.0449262652924809 0.134778795877443 0.177153312234059 0.265729968351089 0.290984282074805 0.290984282074805
Gdap1 ENSMUSG00000025777 0.00283103937188884 0.00849311811566651 0.346527959006435 0.519791938509652 1 1

RNA Polymerase II Pre-transcription Events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mnat1 ENSMUSG00000021103 0.0936419271039906 0.280925781311972 0.452880492349546 0.452880492349546 0.398108175780842 0.452880492349546
Ccnh ENSMUSG00000021548 0.00289311433957183 0.00867934301871549 0.397384062266614 0.596076093399921 1 1
Cdc73 ENSMUSG00000026361 0.00283103937188883 0.0084931181156665 0.577829325134931 0.78180291566155 0.78180291566155 0.78180291566155
Gtf2b ENSMUSG00000028271 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Ncbp1 ENSMUSG00000028330 0.0101222094973346 0.0303666284920038 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803
Polr2b ENSMUSG00000029250 0.120545895661627 0.361637686984882 0.255901190956604 0.383851786434906 0.576973746230334 0.576973746230334
Tcea1 ENSMUSG00000033813 0.0236697127745139 0.0710091383235417 1 1 0.577829325134931 0.866743987702397
Taf9 ENSMUSG00000052293 0.0241933715424143 0.0725801146272428 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155
Gtf2f2 ENSMUSG00000067995 0.197598874030478 0.592796622091434 0.624685493301961 0.624685493301961 0.578113371816017 0.624685493301961
Taf9 ENSMUSG00000078941 0.299349060054895 0.709375484777034 0.709375484777034 0.709375484777034 0.642366752097095 0.709375484777034

black

Ribosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rps5 ENSMUSG00000012848 0.514934023620344 0.772401035430517 0.347639524025037 0.772401035430517 0.853372965654504 0.853372965654504
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rsl24d1 ENSMUSG00000032215 0.17750354896016 0.26625532344024 0.0103546374915853 0.0310639124747558 0.853694531487825 0.853694531487825
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Fau ENSMUSG00000038274 0.455625354715449 0.863737317604735 0.575824878403157 0.863737317604735 0.926333123228344 0.926333123228344
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl21 ENSMUSG00000041453 0.455965611639471 0.78180291566155 0.78180291566155 0.78180291566155 0.576973746230334 0.78180291566155
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl36 ENSMUSG00000057863 0.179945789077372 0.382180685423408 0.254787123615605 0.382180685423408 0.853801250889739 0.853801250889739
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps12 ENSMUSG00000061983 0.148115998140416 0.444347994421247 0.708323672944427 0.852065168704833 0.852065168704833 0.852065168704833
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl17 ENSMUSG00000062328 0.255901190956604 0.383851786434906 0.21549027811633 0.383851786434906 0.853694531487825 0.853694531487825
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Rpl41 ENSMUSG00000093674 0.390750658104795 0.600398061312773 0.400265374208515 0.600398061312773 0.711034989117171 0.711034989117171
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Coronavirus disease - COVID-19

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Irf3 ENSMUSG00000003184 0.853694531487825 0.853694531487825 0.853480389728993 0.853694531487825 0.456305241393103 0.853694531487825
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rps5 ENSMUSG00000012848 0.514934023620344 0.772401035430517 0.347639524025037 0.772401035430517 0.853372965654504 0.853372965654504
C4a ENSMUSG00000015451 0.706831781264721 0.7802108304765 0.7802108304765 0.7802108304765 0.348008842235184 0.7802108304765
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Masp2 ENSMUSG00000028979 0.45596561163947 0.45596561163947 0.45596561163947 0.45596561163947 0.255530331334266 0.45596561163947
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Ikbkb ENSMUSG00000031537 0.711240436189781 0.853801250889739 0.853801250889739 0.853801250889739 0.294820734456232 0.853801250889739
Tyk2 ENSMUSG00000032175 0.642864324224729 0.78180291566155 0.578113371816017 0.78180291566155 0.78180291566155 0.78180291566155
Rsl24d1 ENSMUSG00000032215 0.17750354896016 0.26625532344024 0.0103546374915853 0.0310639124747558 0.853694531487825 0.853694531487825
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Oas3 ENSMUSG00000032661 0.255158975839805 0.382738463759707 0.926278508226733 0.926278508226733 0.0577292451600847 0.173187735480254
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
C1qb ENSMUSG00000036905 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501 0.453570536021945 0.782117202022501
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Fau ENSMUSG00000038274 0.455625354715449 0.863737317604735 0.575824878403157 0.863737317604735 0.926333123228344 0.926333123228344
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl21 ENSMUSG00000041453 0.455965611639471 0.78180291566155 0.78180291566155 0.78180291566155 0.576973746230334 0.78180291566155
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl36 ENSMUSG00000057863 0.179945789077372 0.382180685423408 0.254787123615605 0.382180685423408 0.853801250889739 0.853801250889739
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps12 ENSMUSG00000061983 0.148115998140416 0.444347994421247 0.708323672944427 0.852065168704833 0.852065168704833 0.852065168704833
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl17 ENSMUSG00000062328 0.255901190956604 0.383851786434906 0.21549027811633 0.383851786434906 0.853694531487825 0.853694531487825
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Prkcg ENSMUSG00000078816 0.926333123228344 0.926333123228344 0.853372965654504 0.926333123228344 0.782117202022501 0.926333123228344
Gm5077 ENSMUSG00000079343 0.344663224299303 0.853801250889739 0.853801250889739 0.853801250889739 0.710208797518812 0.853801250889739
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Rpl41 ENSMUSG00000093674 0.390750658104795 0.600398061312773 0.400265374208515 0.600398061312773 0.711034989117171 0.711034989117171
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Oxidative phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Tcirg1 ENSMUSG00000001750 0.255530331334266 0.596076093399921 0.397384062266614 0.596076093399921 0.924872384323463 0.924872384323463
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Atp6v0e ENSMUSG00000015575 0.577829325134931 0.866743987702397 0.92589277149125 0.92589277149125 0.577259514257969 0.866743987702397
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Atp6v0a1 ENSMUSG00000019302 0.711650020253571 0.711854160331342 0.711034989117171 0.711854160331342 0.711854160331342 0.711854160331342
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Atp6v1g2 ENSMUSG00000024403 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501 0.5155648232968 0.782117202022501
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Cox17 ENSMUSG00000046516 0.643359829732651 0.710001140920767 0.299349060054895 0.710001140920767 0.710001140920767 0.710001140920767
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285

Huntington disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Dnah2 ENSMUSG00000005237 0.640861491578951 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Crebbp ENSMUSG00000022521 0.0969812105731562 0.175777610154895 0.117185073436597 0.175777610154895 0.712057867818062 0.712057867818062
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Sod1 ENSMUSG00000022982 0.398108175780842 0.597162263671263 0.120545895661627 0.361637686984882 0.780851835278818 0.780851835278818
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Creb3 ENSMUSG00000028466 0.85117361048289 0.85117361048289 0.18064054691103 0.541921640733091 0.778911768167544 0.85117361048289
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atg14 ENSMUSG00000037526 0.926333123228344 0.926333123228344 0.45596561163947 0.926333123228344 0.78148726569172 0.926333123228344
Polr2j ENSMUSG00000039771 0.575536202757516 0.865889271386954 0.926441990075769 0.926441990075769 0.577259514257969 0.865889271386954
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Dnah7b ENSMUSG00000041144 0.11810342389482 0.354310271684459 0.852940894477647 0.852940894477647 0.710416009055326 0.852940894477647
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Bdnf ENSMUSG00000048482 0.347639524025037 0.926658283600152 0.926658283600152 0.926658283600152 0.642366752097095 0.926658283600152
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Creb5 ENSMUSG00000053007 0.853694531487825 0.853694531487825 0.398469281729516 0.853694531487825 0.780049698709835 0.853694531487825
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Dnaic1 ENSMUSG00000061322 0.511742979522636 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285

Prion disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Hspa1l ENSMUSG00000007033 0.345410946355104 0.518116419532656 1 1 0.044737329683373 0.134211989050119
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Sod1 ENSMUSG00000022982 0.398108175780842 0.597162263671263 0.120545895661627 0.361637686984882 0.780851835278818 0.780851835278818
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cacna1s ENSMUSG00000026407 0.926333123228344 0.926333123228344 0.782117202022501 0.926333123228344 0.455625354715449 0.926333123228344
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Creb3 ENSMUSG00000028466 0.85117361048289 0.85117361048289 0.18064054691103 0.541921640733091 0.778911768167544 0.85117361048289
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cacna1f ENSMUSG00000031142 0.455625354715448 0.711034989117171 0.514934023620345 0.711034989117171 0.711034989117171 0.711034989117171
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
C1qb ENSMUSG00000036905 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501 0.453570536021945 0.782117202022501
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Creb5 ENSMUSG00000053007 0.853694531487825 0.853694531487825 0.398469281729516 0.853694531487825 0.780049698709835 0.853694531487825
Grin2a ENSMUSG00000059003 0.297095062262362 0.445642593393544 0.072627622984314 0.217882868952942 0.642366752097095 0.642366752097095
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
Hspa1b ENSMUSG00000090877 0.214037080764326 0.642111242292977 0.852832278580641 0.852832278580641 0.643853282854191 0.852832278580641

Parkinson disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Trap1 ENSMUSG00000005981 0.255901190956604 0.676192245442677 0.853372965654504 0.853372965654504 0.450794830295118 0.676192245442677
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Camk2a ENSMUSG00000024617 0.711854160331342 0.712057867818062 0.712057867818062 0.712057867818062 0.456305241393103 0.712057867818062
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Amyotrophic lateral sclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Rab8a ENSMUSG00000003037 0.447265995733381 0.563485358844814 0.255901190956604 0.563485358844814 0.563485358844814 0.563485358844814
Dnah2 ENSMUSG00000005237 0.640861491578951 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Ubqln4 ENSMUSG00000008604 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781 0.711034989117171 0.711240436189781
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Nxf1 ENSMUSG00000010097 0.455625354715448 0.683438032073173 0.711650020253571 0.711650020253571 0.346527959006435 0.683438032073173
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Sod1 ENSMUSG00000022982 0.398108175780842 0.597162263671263 0.120545895661627 0.361637686984882 0.780851835278818 0.780851835278818
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Srsf7 ENSMUSG00000024097 0.712057867818062 0.78180291566155 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
3110043O21Rik ENSMUSG00000028300 1 1 0.142830916318171 0.428492748954512 1 1
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Sec13 ENSMUSG00000030298 0.782117202022501 0.853372965654504 0.643853282854191 0.853372965654504 0.853372965654504 0.853372965654504
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Hdac6 ENSMUSG00000031161 0.573498913947369 0.578113371816017 0.344663224299303 0.578113371816017 0.578113371816017 0.578113371816017
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Nup37 ENSMUSG00000035351 0.853801250889739 0.853801250889739 0.511742979522636 0.853801250889739 0.853372965654504 0.853801250889739
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Sigmar1 ENSMUSG00000036078 0.926658283600152 0.926658283600152 0.853694531487825 0.926658283600152 0.400265374208515 0.926658283600152
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Nxt1 ENSMUSG00000036992 0.926333123228344 0.926333123228344 0.710416009055326 0.926333123228344 0.57466664340579 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atg14 ENSMUSG00000037526 0.926333123228344 0.926333123228344 0.45596561163947 0.926333123228344 0.78148726569172 0.926333123228344
Nup205 ENSMUSG00000038759 0.214037080764326 0.642111242292977 0.712057867818062 0.853694531487825 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Dnah7b ENSMUSG00000041144 0.11810342389482 0.354310271684459 0.852940894477647 0.852940894477647 0.710416009055326 0.852940894477647
Tardbp ENSMUSG00000041459 1 1 0.34837756124189 1 1 1
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Atxn2 ENSMUSG00000042605 0.0331400397096515 0.0994201191289545 0.454942951775341 0.682414427663012 0.926550375688041 0.926550375688041
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Hnrnpa1 ENSMUSG00000046434 0.514300775319626 0.577829325134931 0.456305241393103 0.577829325134931 0.577829325134931 0.577829325134931
Pom121 ENSMUSG00000053293 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Grin2a ENSMUSG00000059003 0.297095062262362 0.445642593393544 0.072627622984314 0.217882868952942 0.642366752097095 0.642366752097095
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Dnaic1 ENSMUSG00000061322 0.511742979522636 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Nrg1 ENSMUSG00000062991 0.0947558980989549 0.222173997210623 0.148115998140416 0.222173997210623 0.576112968612194 0.576112968612194
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Srsf3 ENSMUSG00000071172 0.926658283600152 0.926658283600152 0.780851835278818 0.926658283600152 0.710416009055326 0.926658283600152
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Galnt1 ENSMUSG00000000420 0.853372965654504 0.926550375688041 0.926550375688041 0.926550375688041 0.254414773803597 0.763244321410791
Srr ENSMUSG00000001323 0.514300775319626 0.771451162979439 0.348008842235184 0.771451162979439 0.926658283600152 0.926658283600152
Akr1b3 ENSMUSG00000001642 0.853372965654504 0.853801250889739 0.392985378348026 0.853801250889739 0.853801250889739 0.853801250889739
Tcirg1 ENSMUSG00000001750 0.255530331334266 0.596076093399921 0.397384062266614 0.596076093399921 0.924872384323463 0.924872384323463
Gmpr2 ENSMUSG00000002326 0.505169133438821 0.757753700158231 0.179945789077372 0.539837367232116 1 1
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Gnmt ENSMUSG00000002769 0.775217051297351 0.92356607045265 0.197598874030478 0.592796622091434 0.92356607045265 0.92356607045265
Prodh ENSMUSG00000003526 0.0763619660358786 0.229085898107636 0.456305241393103 0.514300775319626 0.514300775319626 0.514300775319626
Gstm5 ENSMUSG00000004032 0.0953125666339397 0.285937699901819 0.643359829732651 0.643359829732651 0.578113371816017 0.643359829732651
Sgsh ENSMUSG00000005043 0.849457568495547 0.849457568495547 0.213307944885796 0.639923834657388 0.562539849036184 0.843809773554277
Hmox1 ENSMUSG00000005413 0.00253244992826164 0.00759734978478493 0.447621891168214 0.67143283675232 0.926333123228344 0.926333123228344
Inpp5k ENSMUSG00000006127 0.513026869856283 0.578113371816017 0.29252580908486 0.578113371816017 0.578113371816017 0.578113371816017
Elovl1 ENSMUSG00000006390 0.640861491578951 0.853372965654504 0.853372965654504 0.853372965654504 0.295581119060361 0.853372965654504
Mgst1 ENSMUSG00000008540 0.573498913947369 0.964296486337094 0.642864324224729 0.964296486337094 1 1
Fpgs ENSMUSG00000009566 0.024062085667391 0.0721862570021729 0.300095920620218 0.450143880930327 0.711854160331342 0.711854160331342
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Kdsr ENSMUSG00000009905 0.643359829732651 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Pigyl ENSMUSG00000010607 0.148115998140415 0.444347994421246 0.572616808177226 0.85117361048289 0.85117361048289 0.85117361048289
Acaa1b ENSMUSG00000010651 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.573205482926791 0.711034989117171
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Dguok ENSMUSG00000014554 0.505169133438821 0.757753700158231 0.853801250889739 0.853801250889739 0.398829756175299 0.757753700158231
Atp6v0e ENSMUSG00000015575 0.577829325134931 0.866743987702397 0.92589277149125 0.92589277149125 0.577259514257969 0.866743987702397
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Atp6v0a1 ENSMUSG00000019302 0.711650020253571 0.711854160331342 0.711034989117171 0.711854160331342 0.711854160331342 0.711854160331342
Smpd2 ENSMUSG00000019822 0.0763619660358787 0.229085898107636 0.514934023620345 0.772401035430517 1 1
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Phykpl ENSMUSG00000020359 0.853801250889739 0.853801250889739 0.147458757705094 0.442376273115283 0.576973746230334 0.853801250889739
Aspa ENSMUSG00000020774 0.146141353215795 0.438424059647386 0.298599969973533 0.4478999549603 0.926658283600152 0.926658283600152
Nme2 ENSMUSG00000020857 0.213307944885796 0.639923834657388 0.706616781330066 0.706616781330066 0.453225835454266 0.679838753181399
Adprm ENSMUSG00000020910 0.711650020253571 0.711650020253571 0.347639524025037 0.711650020253571 0.711240436189781 0.711650020253571
Gstz1 ENSMUSG00000021033 0.455625354715448 0.851061028660105 0.851061028660105 0.851061028660105 0.7802108304765 0.851061028660105
Ippk ENSMUSG00000021385 0.575536202757516 0.863304304136274 0.45596561163947 0.863304304136274 1 1
Fbp2 ENSMUSG00000021456 0.92622377157404 0.92622377157404 0.639337105615665 0.92622377157404 0.639337105615665 0.92622377157404
Sptlc1 ENSMUSG00000021468 0.852832278580641 0.852832278580641 0.147458757705095 0.442376273115284 0.780851835278818 0.852832278580641
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Tgds ENSMUSG00000022130 0.513665062682276 0.710001140920767 0.399548817627028 0.710001140920767 0.710001140920767 0.710001140920767
Dhrs4 ENSMUSG00000022210 0.347639524025037 0.711854160331342 0.711034989117171 0.711854160331342 0.711854160331342 0.711854160331342
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Dgat1 ENSMUSG00000022555 0.513665062682276 0.772401035430517 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501
Tsta3 ENSMUSG00000022570 0.447621891168214 0.67143283675232 0.17750354896016 0.532510646880481 1 1
Pycrl ENSMUSG00000022571 0.926441990075769 0.926441990075769 0.29252580908486 0.438788713627291 0.29252580908486 0.438788713627291
St3gal6 ENSMUSG00000022747 0.456305241393104 0.684457862089656 0.252920381501207 0.684457862089656 0.707899741868332 0.707899741868332
Nit2 ENSMUSG00000022751 0.782117202022501 0.782117202022501 0.5155648232968 0.782117202022501 0.7802108304765 0.782117202022501
Umps ENSMUSG00000022814 0.853480389728993 0.853480389728993 0.0761127945805736 0.114542949053818 0.0763619660358785 0.114542949053818
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Pigp ENSMUSG00000022940 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Cbr3 ENSMUSG00000022947 0.171503747555202 0.514511242665607 0.514934023620345 0.570836132666921 0.570836132666921 0.570836132666921
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Rpp14 ENSMUSG00000023156 0.710416009055326 0.776243028387552 0.118714930081337 0.35614479024401 0.776243028387552 0.776243028387552
Acy1 ENSMUSG00000023262 0.17750354896016 0.255530331334266 0.216214347033995 0.255530331334266 0.255530331334266 0.255530331334266
Pisd ENSMUSG00000023452 1 1 0.298599969973533 0.895799909920599 0.926550375688041 1
Pigx ENSMUSG00000023791 0.853480389728993 0.853480389728993 0.708745765211584 0.853480389728993 0.21549027811633 0.64647083434899
Synj2 ENSMUSG00000023805 0.853372965654504 0.853372965654504 0.78180291566155 0.853372965654504 0.514934023620345 0.853372965654504
Enpp4 ENSMUSG00000023961 0.852065168704833 0.852065168704833 0.21549027811633 0.64647083434899 0.641867098978198 0.852065168704833
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Pigf ENSMUSG00000024145 0.45596561163947 0.683948417459205 0.853801250889739 0.853801250889739 0.0443599545252853 0.133079863575856
Atp6v1g2 ENSMUSG00000024403 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501 0.5155648232968 0.782117202022501
Psat1 ENSMUSG00000024640 0.120850531362929 0.362551594088788 0.456305241393103 0.5155648232968 0.5155648232968 0.5155648232968
Tm7sf2 ENSMUSG00000024799 0.120850531362929 0.362551594088788 0.454942951775342 0.682414427663012 0.708745765211584 0.708745765211584
Pcyt2 ENSMUSG00000025137 0.255530331334266 0.383295497001398 0.255530331334266 0.383295497001398 0.780851835278818 0.780851835278818
Sirt7 ENSMUSG00000025138 0.21549027811633 0.323235417174495 0.120850531362929 0.323235417174495 0.334323804341915 0.334323804341915
Hsd17b10 ENSMUSG00000025260 0.254414773803597 0.763244321410791 0.780851835278818 1 1 1
Sat1 ENSMUSG00000025283 0.7802108304765 0.7802108304765 0.513665062682276 0.770497594023414 0.511097249598474 0.770497594023414
Nnt ENSMUSG00000025453 0.400265374208515 0.57466664340579 0.348008842235185 0.57466664340579 0.57466664340579 0.57466664340579
Echs1 ENSMUSG00000025465 0.216214347033995 0.648643041101984 0.926441990075769 0.926441990075769 0.573498913947369 0.860248370921054
Gusb ENSMUSG00000025534 0.455965611639469 0.455965611639469 0.298599969973533 0.450143880930327 0.300095920620218 0.450143880930327
Tyms ENSMUSG00000025747 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.254787123615605 0.764361370846816
Nudt5 ENSMUSG00000025817 0.45596561163947 0.577829325134931 0.399548817627028 0.577829325134931 0.577829325134931 0.577829325134931
Rdh10 ENSMUSG00000025921 1 1 0.443669460449296 0.665504190673943 0.295581119060361 0.665504190673943
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Dtymk ENSMUSG00000026281 0.926550375688041 0.926550375688041 0.710208797518812 0.926550375688041 0.299349060054895 0.898047180164686
Pfkfb2 ENSMUSG00000026409 0.853801250889739 0.853801250889739 0.454942951775341 0.682414427663012 0.338976281569377 0.682414427663012
Fh1 ENSMUSG00000026526 0.853372965654504 0.853372965654504 0.643359829732651 0.853372965654504 0.641867098978198 0.853372965654504
Uck2 ENSMUSG00000026558 0.256271555563966 0.768814666691898 0.642366752097095 0.852832278580641 0.852832278580641 0.852832278580641
Hsd17b7 ENSMUSG00000026675 0.0763619660358786 0.229085898107636 0.577829325134931 0.866743987702397 1 1
Pigc ENSMUSG00000026698 0.853694531487825 0.853694531487825 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Dpm2 ENSMUSG00000026810 0.148772260628989 0.446316781886968 0.45596561163947 0.683948417459205 0.78148726569172 0.78148726569172
Lpcat4 ENSMUSG00000027134 0.300095920620218 0.852504981253341 0.852504981253341 0.852504981253341 0.578113371816017 0.852504981253341
Dut ENSMUSG00000027203 0.578113371816017 0.712057867818062 0.712057867818062 0.712057867818062 0.711854160331342 0.712057867818062
Ivd ENSMUSG00000027332 0.780851835278818 0.853801250889739 0.853801250889739 0.853801250889739 0.252545530864481 0.757636592593443
Idh3b ENSMUSG00000027406 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.399548817627028 0.781170242226513
Ggt7 ENSMUSG00000027603 0.781170242226513 0.926333123228344 0.148115998140416 0.444347994421247 0.926333123228344 0.926333123228344
Nfs1 ENSMUSG00000027618 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152 0.711854160331342 0.926658283600152
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndst3 ENSMUSG00000027977 0.5155648232968 1 0.853907737111068 1 1 1
Pip5k1a ENSMUSG00000028126 0.782117202022501 0.782117202022501 0.398829756175299 0.681901202923927 0.454600801949285 0.681901202923927
Adh5 ENSMUSG00000028138 0.178901132102685 0.268874530827074 0.17924968721805 0.268874530827074 0.852504981253341 0.852504981253341
Cth ENSMUSG00000028179 0.144820068500793 0.268351698154027 0.178901132102685 0.268351698154027 0.924872384323464 0.924872384323464
Coq3 ENSMUSG00000028247 0.643359829732651 0.643359829732651 0.45596561163947 0.643359829732651 0.400265374208515 0.643359829732651
Nudt2 ENSMUSG00000028443 0.711650020253571 0.711854160331342 0.0761127945805735 0.228338383741721 0.711854160331342 0.711854160331342
Npr2 ENSMUSG00000028469 0.21549027811633 0.323235417174495 0.0753654386865988 0.226096316059796 0.398829756175299 0.398829756175299
Scp2 ENSMUSG00000028603 0.45596561163947 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Ppcs ENSMUSG00000028636 0.926441990075769 0.926441990075769 0.514934023620345 0.772401035430517 0.146141353215796 0.438424059647387
Trit1 ENSMUSG00000028653 0.640861491578951 0.640861491578951 0.213307944885796 0.593892267963669 0.395928178642446 0.593892267963669
Ppt1 ENSMUSG00000028657 0.0240620856673909 0.0721862570021727 0.853907737111068 0.853907737111068 0.782117202022501 0.853907737111068
Urod ENSMUSG00000028684 0.926658283600152 0.926658283600152 0.397384062266614 0.926658283600152 0.926550375688041 0.926658283600152
Cda ENSMUSG00000028755 0.577259514257969 0.577259514257969 0.119631084167592 0.358893252502775 0.399548817627028 0.577259514257969
Mecr ENSMUSG00000028910 0.215852522998048 0.637013771824329 0.513346277289108 0.637013771824329 0.637013771824329 0.637013771824329
Khk ENSMUSG00000029162 0.642366752097095 0.853694531487825 0.348008842235184 0.853694531487825 0.853694531487825 0.853694531487825
Paics ENSMUSG00000029247 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.511097249598474 0.511097249598474
Agpat9 ENSMUSG00000029314 0.5155648232968 0.711034989117171 0.0964252305385472 0.289275691615642 0.711034989117171 0.711034989117171
Psph ENSMUSG00000029446 0.00660511570760555 0.0198153471228166 0.572616808177226 0.572616808177226 0.454600801949285 0.572616808177226
Sirt4 ENSMUSG00000029524 0.21549027811633 0.64647083434899 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Gstk1 ENSMUSG00000029864 0.0331400397096515 0.0994201191289544 0.852832278580641 0.852832278580641 0.578113371816017 0.852832278580641
Nat8 ENSMUSG00000030004 0.0168921052924601 0.0506763158773803 0.300095920620218 0.300095920620218 0.216214347033995 0.300095920620218
Etnk1 ENSMUSG00000030275 0.781170242226513 0.852832278580641 0.0426702157436794 0.128010647231038 0.852832278580641 0.852832278580641
Slc27a5 ENSMUSG00000030382 0.0726276229843141 0.181275797044394 0.92622377157404 0.92622377157404 0.120850531362929 0.181275797044394
Cyp2r1 ENSMUSG00000030670 0.13849172243875 0.415475167316251 0.851061028660105 0.924930181917758 0.924930181917758 0.924930181917758
Acadsb ENSMUSG00000030861 0.0592616003460511 0.177784801038153 0.25141795904251 0.377126938563765 0.926333123228344 0.926333123228344
Oat ENSMUSG00000030934 0.509798138101151 0.703556284613037 0.633039971999413 0.703556284613037 0.703556284613037 0.703556284613037
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Mtm1 ENSMUSG00000031337 0.853694531487825 0.853694531487825 0.853587578053106 0.853694531487825 0.254041925545275 0.762125776635825
Agpat5 ENSMUSG00000031467 0.346527959006435 0.926003599371282 0.641867098978198 0.926003599371282 0.926003599371282 0.926003599371282
Pgls ENSMUSG00000031807 0.0847074989275803 0.12706124839137 0.443306001726868 0.443306001726868 0.0241933715424143 0.0725801146272428
Hsd17b2 ENSMUSG00000031844 0.446552171959625 0.702664132234038 0.622066039218108 0.702664132234038 0.702664132234038 0.702664132234038
Pts ENSMUSG00000032067 0.782117202022501 0.782117202022501 0.299349060054895 0.521459286037555 0.347639524025037 0.521459286037555
Glce ENSMUSG00000032252 0.211110344399808 0.323235417174495 0.21549027811633 0.323235417174495 0.853801250889739 0.853801250889739
Bckdhb ENSMUSG00000032263 0.852832278580641 0.926278508226733 0.926278508226733 0.926278508226733 0.852832278580641 0.926278508226733
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Nme6 ENSMUSG00000032478 0.255530331334266 0.56903312490074 0.56903312490074 0.56903312490074 0.384672302267076 0.56903312490074
Mcee ENSMUSG00000033429 0.926441990075769 0.926441990075769 0.0592616003460512 0.177784801038154 0.711240436189781 0.926441990075769
Idua ENSMUSG00000033540 0.578113371816017 0.643853282854191 0.5155648232968 0.643853282854191 0.643853282854191 0.643853282854191
Ptplad1 ENSMUSG00000033629 0.853372965654504 0.926550375688041 0.0721303428592824 0.216391028577847 0.926550375688041 0.926550375688041
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Tmem5 ENSMUSG00000034620 0.577259514257969 0.642366752097095 0.642366752097095 0.642366752097095 0.252920381501207 0.642366752097095
Dgkh ENSMUSG00000034731 0.148115998140416 0.314455120949809 0.209636747299872 0.314455120949809 0.925331064166297 0.925331064166297
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Mgat5 ENSMUSG00000036155 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.455625354715448 0.5155648232968
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Alg5 ENSMUSG00000036632 0.853694531487825 0.853694531487825 0.709375484777034 0.853694531487825 0.252545530864481 0.757636592593443
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Amdhd2 ENSMUSG00000036820 0.0753654386865988 0.226096316059796 0.578113371816017 0.711034989117171 0.711034989117171 0.711034989117171
Ehmt1 ENSMUSG00000036893 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.514934023620344 0.853801250889739
Hk1 ENSMUSG00000037012 0.642864324224729 0.852940894477647 0.852940894477647 0.852940894477647 0.400265374208515 0.852940894477647
Setd7 ENSMUSG00000037111 0.256271555563966 0.514934023620345 0.45596561163947 0.514934023620345 0.514934023620345 0.514934023620345
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Man1c1 ENSMUSG00000037306 0.926658283600152 0.926658283600152 0.711650020253571 0.926658283600152 0.781170242226513 0.926658283600152
Pank2 ENSMUSG00000037514 0.710001140920767 0.710001140920767 0.576973746230334 0.710001140920767 0.578113371816017 0.710001140920767
Gnpnat1 ENSMUSG00000037722 0.21549027811633 0.323235417174495 0.0936419271039908 0.280925781311972 0.643359829732651 0.643359829732651
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Pigk ENSMUSG00000039047 0.0964252305385471 0.16283148250234 0.108554321668226 0.16283148250234 0.381566259882379 0.381566259882379
Adk ENSMUSG00000039197 0.78148726569172 0.853801250889739 0.853801250889739 0.853801250889739 0.643359829732651 0.853801250889739
Hexdc ENSMUSG00000039307 0.514300775319626 0.514300775319626 0.347639524025037 0.514300775319626 0.395196379647461 0.514300775319626
Ccbl1 ENSMUSG00000039648 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152 0.853907737111068 0.926658283600152
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Mars ENSMUSG00000040354 0.514934023620345 0.7733472349452 0.853801250889739 0.853801250889739 0.5155648232968 0.7733472349452
Blvrb ENSMUSG00000040466 0.399548817627028 0.599323226440542 0.341647690705446 0.599323226440542 0.924286968561133 0.924286968561133
Hibch ENSMUSG00000041426 0.453225835454266 0.679838753181399 0.146141353215796 0.438424059647387 0.776919261684345 0.776919261684345
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Csgalnact2 ENSMUSG00000042042 0.782117202022501 0.853694531487825 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825
Bhmt2 ENSMUSG00000042118 0.255530331334266 0.766590994002797 0.712057867818062 1 1 1
Dctpp1 ENSMUSG00000042462 0.283134662157423 0.424701993236134 0.148772260628989 0.424701993236134 0.777255087907932 0.777255087907932
Dpm3 ENSMUSG00000042737 0.348008842235184 0.522013263352776 0.347639524025037 0.522013263352776 0.926550375688041 0.926550375688041
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Pigw ENSMUSG00000045140 0.706616781330066 0.706616781330066 0.178901132102685 0.441659526834679 0.294439684556453 0.441659526834679
Fahd1 ENSMUSG00000045316 0.926003599371281 0.926003599371281 0.708534948098331 0.926003599371281 0.640861491578951 0.926003599371281
Cox17 ENSMUSG00000046516 0.643359829732651 0.710001140920767 0.299349060054895 0.710001140920767 0.710001140920767 0.710001140920767
Setd8 ENSMUSG00000049327 0.577829325134931 0.780851835278818 0.177153312234059 0.531459936702178 0.780851835278818 0.780851835278818
Ptges ENSMUSG00000050737 0.78180291566155 0.78180291566155 0.148115998140416 0.444347994421247 0.399548817627028 0.599323226440542
B3galt6 ENSMUSG00000050796 0.853694531487825 0.853907737111068 0.0168921052924602 0.0506763158773805 0.853907737111068 0.853907737111068
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Suclg1 ENSMUSG00000052738 0.643359829732651 0.643359829732651 0.511742979522636 0.643359829732651 0.642864324224729 0.643359829732651
Ggcx ENSMUSG00000053460 1 1 0.781170242226513 1 0.852940894477647 1
Rpia ENSMUSG00000053604 0.926604389137101 0.926604389137101 0.515249728559995 0.772874592839992 0.514617706526787 0.772874592839992
Mat2a ENSMUSG00000053907 0.256271555563967 0.577259514257969 0.400265374208515 0.577259514257969 0.577259514257969 0.577259514257969
Lclat1 ENSMUSG00000054469 0.400265374208515 0.576973746230334 0.45596561163947 0.576973746230334 0.576973746230334 0.576973746230334
Gadl1 ENSMUSG00000056880 0.577259514257969 0.779238691542963 0.640861491578951 0.779238691542963 0.779238691542963 0.779238691542963
Cml1 ENSMUSG00000057103 0.255901190956604 0.383851786434906 0.398829756175299 0.398829756175299 0.255530331334266 0.383851786434906
Aadat ENSMUSG00000057228 0.926333123228344 0.926333123228344 0.0969812105731562 0.290943631719469 0.853694531487825 0.926333123228344
Hadhb ENSMUSG00000059447 0.514934023620345 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Pla2g16 ENSMUSG00000060675 0.299349060054895 0.643853282854191 0.577829325134931 0.643853282854191 0.643853282854191 0.643853282854191
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Akr1b10 ENSMUSG00000061758 0.511742979522636 0.7733472349452 0.5155648232968 0.7733472349452 0.853049270252403 0.853049270252403
Mppe1 ENSMUSG00000062526 0.0117179415987428 0.0351538247962283 0.0753654386865987 0.113048158029898 0.926658283600152 0.926658283600152
Cyp26b1 ENSMUSG00000063415 0.252545530864481 0.392243127063687 0.392243127063687 0.392243127063687 0.346899083932133 0.392243127063687
Hsd3b2 ENSMUSG00000063730 0.455625354715449 0.683438032073173 0.926658283600152 0.926658283600152 0.146141353215796 0.438424059647387
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Rdh11 ENSMUSG00000066441 0.926333123228344 0.926333123228344 0.925331064166297 0.926333123228344 0.567513221841557 0.926333123228344
Mthfs ENSMUSG00000066442 0.578113371816017 0.711034989117171 0.146141353215796 0.438424059647387 0.711034989117171 0.711034989117171
Ugt2b36 ENSMUSG00000070704 0.54332839150188 0.691038632946509 0.691038632946509 0.691038632946509 0.617271014427057 0.691038632946509
Pgap1 ENSMUSG00000073678 0.0315593554855452 0.0946780664566357 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Alg6 ENSMUSG00000073792 0.298224585822431 0.753185793980836 0.850036160745954 0.850036160745954 0.502123862653891 0.753185793980836
Il4i1 ENSMUSG00000074141 0.578113371816017 0.710001140920767 0.392985378348026 0.710001140920767 0.710001140920767 0.710001140920767
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
Amy1 ENSMUSG00000074264 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041
Itpa ENSMUSG00000074797 0.924639851733043 0.925217182211634 0.0969812105731562 0.290943631719469 0.925217182211634 0.925217182211634
B3galt5 ENSMUSG00000074892 0.782117202022501 0.782117202022501 0.643359829732651 0.782117202022501 0.711240436189781 0.782117202022501
Amd1 ENSMUSG00000075232 0.711854160331342 0.711854160331342 0.255530331334266 0.711854160331342 0.711034989117171 0.711854160331342
Gpx4 ENSMUSG00000075706 0.171859370212435 0.515578110637306 0.400265374208515 0.600398061312773 0.852504981253341 0.852504981253341
Gm2382 ENSMUSG00000079427 0.397384062266614 0.397384062266614 0.254414773803597 0.397384062266614 0.395928178642446 0.397384062266614
Cers1 ENSMUSG00000087408 0.514934023620345 0.772401035430517 0.455625354715449 0.772401035430517 0.926333123228344 0.926333123228344
Uckl1 ENSMUSG00000089917 0.255901190956604 0.383851786434906 0.214037080764326 0.383851786434906 0.78180291566155 0.78180291566155
Car15 ENSMUSG00000090236 0.180293335960318 0.511097249598474 0.447621891168214 0.511097249598474 0.511097249598474 0.511097249598474

Thermogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Creb3 ENSMUSG00000028466 0.85117361048289 0.85117361048289 0.18064054691103 0.541921640733091 0.778911768167544 0.85117361048289
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Sos2 ENSMUSG00000034801 0.179945789077372 0.539837367232115 0.577829325134931 0.577829325134931 0.455625354715449 0.577829325134931
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Cox17 ENSMUSG00000046516 0.643359829732651 0.710001140920767 0.299349060054895 0.710001140920767 0.710001140920767 0.710001140920767
Selrc1 ENSMUSG00000048351 0.511742979522636 0.767614469283954 0.511097249598474 0.767614469283954 0.926658283600152 0.926658283600152
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Creb5 ENSMUSG00000053007 0.853694531487825 0.853694531487825 0.398469281729516 0.853694531487825 0.780049698709835 0.853694531487825
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
1810043H04Rik ENSMUSG00000078572 0.513026869856283 0.513665062682276 0.395928178642446 0.513665062682276 0.513665062682276 0.513665062682276
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Non-alcoholic fatty liver disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Ikbkb ENSMUSG00000031537 0.711240436189781 0.853801250889739 0.853801250889739 0.853801250889739 0.294820734456232 0.853801250889739
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Gsk3a ENSMUSG00000057177 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342 0.348008842235184 0.711854160331342
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Ager ENSMUSG00000015452 0.578113371816017 0.641867098978198 0.641867098978198 0.641867098978198 0.514300775319626 0.641867098978198
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Camk2a ENSMUSG00000024617 0.711854160331342 0.712057867818062 0.712057867818062 0.712057867818062 0.456305241393103 0.712057867818062
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
Prkcg ENSMUSG00000078816 0.926333123228344 0.926333123228344 0.853372965654504 0.926333123228344 0.782117202022501 0.926333123228344

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.397384062266614 0.577829325134931 0.577829325134931 0.577829325134931 0.348008842235184 0.577829325134931
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Araf ENSMUSG00000001127 0.513026869856283 0.635703516568382 0.635703516568382 0.635703516568382 0.577259514257969 0.635703516568382
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Rab8a ENSMUSG00000003037 0.447265995733381 0.563485358844814 0.255901190956604 0.563485358844814 0.563485358844814 0.563485358844814
Dnah2 ENSMUSG00000005237 0.640861491578951 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Trap1 ENSMUSG00000005981 0.255901190956604 0.676192245442677 0.853372965654504 0.853372965654504 0.450794830295118 0.676192245442677
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Csf1 ENSMUSG00000014599 0.853372965654504 0.853372965654504 0.346527959006435 0.519791938509652 0.297848640636702 0.519791938509652
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Ager ENSMUSG00000015452 0.578113371816017 0.641867098978198 0.641867098978198 0.641867098978198 0.514300775319626 0.641867098978198
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Sod1 ENSMUSG00000022982 0.398108175780842 0.597162263671263 0.120545895661627 0.361637686984882 0.780851835278818 0.780851835278818
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Camk2a ENSMUSG00000024617 0.711854160331342 0.712057867818062 0.712057867818062 0.712057867818062 0.456305241393103 0.712057867818062
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Hsd17b10 ENSMUSG00000025260 0.254414773803597 0.763244321410791 0.780851835278818 1 1 1
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cacna1s ENSMUSG00000026407 0.926333123228344 0.926333123228344 0.782117202022501 0.926333123228344 0.455625354715449 0.926333123228344
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
3110043O21Rik ENSMUSG00000028300 1 1 0.142830916318171 0.428492748954512 1 1
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cacna1f ENSMUSG00000031142 0.455625354715448 0.711034989117171 0.514934023620345 0.711034989117171 0.711034989117171 0.711034989117171
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Sigmar1 ENSMUSG00000036078 0.926658283600152 0.926658283600152 0.853694531487825 0.926658283600152 0.400265374208515 0.926658283600152
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atg14 ENSMUSG00000037526 0.926333123228344 0.926333123228344 0.45596561163947 0.926333123228344 0.78148726569172 0.926333123228344
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Dnah7b ENSMUSG00000041144 0.11810342389482 0.354310271684459 0.852940894477647 0.852940894477647 0.710416009055326 0.852940894477647
Tardbp ENSMUSG00000041459 1 1 0.34837756124189 1 1 1
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Atxn2 ENSMUSG00000042605 0.0331400397096515 0.0994201191289545 0.454942951775341 0.682414427663012 0.926550375688041 0.926550375688041
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Bdnf ENSMUSG00000048482 0.347639524025037 0.926658283600152 0.926658283600152 0.926658283600152 0.642366752097095 0.926658283600152
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Grin2a ENSMUSG00000059003 0.297095062262362 0.445642593393544 0.072627622984314 0.217882868952942 0.642366752097095 0.642366752097095
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Dnaic1 ENSMUSG00000061322 0.511742979522636 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157 0.637274134311157
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285
Prkcg ENSMUSG00000078816 0.926333123228344 0.926333123228344 0.853372965654504 0.926333123228344 0.782117202022501 0.926333123228344
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.397384062266614 0.577829325134931 0.577829325134931 0.577829325134931 0.348008842235184 0.577829325134931
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Araf ENSMUSG00000001127 0.513026869856283 0.635703516568382 0.635703516568382 0.635703516568382 0.577259514257969 0.635703516568382
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Csf1 ENSMUSG00000014599 0.853372965654504 0.853372965654504 0.346527959006435 0.519791938509652 0.297848640636702 0.519791938509652
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Ager ENSMUSG00000015452 0.578113371816017 0.641867098978198 0.641867098978198 0.641867098978198 0.514300775319626 0.641867098978198
Slc25a5 ENSMUSG00000016319 0.926550375688041 0.926550375688041 0.710416009055326 0.926550375688041 0.853372965654504 0.926550375688041
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Uqcr11 ENSMUSG00000020163 0.254787123615605 0.516994836448954 0.344663224299303 0.516994836448954 0.852504981253341 0.852504981253341
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Klc2 ENSMUSG00000024862 0.926658283600152 0.926658283600152 0.578113371816017 0.926658283600152 0.853694531487825 0.926658283600152
Hsd17b10 ENSMUSG00000025260 0.254414773803597 0.763244321410791 0.780851835278818 1 1 1
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cacna1s ENSMUSG00000026407 0.926333123228344 0.926333123228344 0.782117202022501 0.926333123228344 0.455625354715449 0.926333123228344
Kif5c ENSMUSG00000026764 0.297095062262363 0.766645874397711 0.511097249598474 0.766645874397711 0.924987846321933 0.924987846321933
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cacna1f ENSMUSG00000031142 0.455625354715448 0.711034989117171 0.514934023620345 0.711034989117171 0.711034989117171 0.711034989117171
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Ikbkb ENSMUSG00000031537 0.711240436189781 0.853801250889739 0.853801250889739 0.853801250889739 0.294820734456232 0.853801250889739
Cox7a2 ENSMUSG00000032330 0.575824878403157 0.863737317604735 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atg14 ENSMUSG00000037526 0.926333123228344 0.926333123228344 0.45596561163947 0.926333123228344 0.78148726569172 0.926333123228344
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Shfm1 ENSMUSG00000042541 0.398829756175299 0.643359829732651 0.643359829732651 0.643359829732651 0.513026869856283 0.643359829732651
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Grin2a ENSMUSG00000059003 0.297095062262362 0.445642593393544 0.072627622984314 0.217882868952942 0.642366752097095 0.642366752097095
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cox5b ENSMUSG00000061518 0.853801250889739 0.853801250889739 0.397384062266614 0.679838753181399 0.453225835454266 0.679838753181399
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Cox7a1 ENSMUSG00000074218 0.395196379647461 0.454600801949285 0.454600801949285 0.454600801949285 0.180640546911031 0.454600801949285

Retrograde endocannabinoid signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufa11 ENSMUSG00000002379 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344 0.853049270252403 0.926333123228344
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufs4 ENSMUSG00000021764 0.853694531487825 0.853907737111068 0.853907737111068 0.853907737111068 0.395928178642446 0.853907737111068
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cacna1s ENSMUSG00000026407 0.926333123228344 0.926333123228344 0.782117202022501 0.926333123228344 0.455625354715449 0.926333123228344
Gnb4 ENSMUSG00000027669 0.300095920620218 0.852504981253341 0.852504981253341 0.852504981253341 0.778911768167544 0.852504981253341
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cacna1f ENSMUSG00000031142 0.455625354715448 0.711034989117171 0.514934023620345 0.711034989117171 0.711034989117171 0.711034989117171
Gnao1 ENSMUSG00000031748 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Gng11 ENSMUSG00000032766 0.0766111619812296 0.229833485943689 0.711034989117171 1 1 1
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Dagla ENSMUSG00000035735 1 1 1 1 1 1
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa4l2 ENSMUSG00000040280 0.782117202022501 0.782117202022501 0.216214347033995 0.324321520550992 0.148115998140416 0.324321520550992
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Prkcg ENSMUSG00000078816 0.926333123228344 0.926333123228344 0.853372965654504 0.926333123228344 0.782117202022501 0.926333123228344

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pigyl ENSMUSG00000010607 0.148115998140415 0.444347994421246 0.572616808177226 0.85117361048289 0.85117361048289 0.85117361048289
Pigp ENSMUSG00000022940 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Pigx ENSMUSG00000023791 0.853480389728993 0.853480389728993 0.708745765211584 0.853480389728993 0.21549027811633 0.64647083434899
Pigf ENSMUSG00000024145 0.45596561163947 0.683948417459205 0.853801250889739 0.853801250889739 0.0443599545252853 0.133079863575856
Pigc ENSMUSG00000026698 0.853694531487825 0.853694531487825 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Dpm2 ENSMUSG00000026810 0.148772260628989 0.446316781886968 0.45596561163947 0.683948417459205 0.78148726569172 0.78148726569172
Pigk ENSMUSG00000039047 0.0964252305385471 0.16283148250234 0.108554321668226 0.16283148250234 0.381566259882379 0.381566259882379
Pigw ENSMUSG00000045140 0.706616781330066 0.706616781330066 0.178901132102685 0.441659526834679 0.294439684556453 0.441659526834679
Mppe1 ENSMUSG00000062526 0.0117179415987428 0.0351538247962283 0.0753654386865987 0.113048158029898 0.926658283600152 0.926658283600152
Pgap1 ENSMUSG00000073678 0.0315593554855452 0.0946780664566357 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041

Base excision repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mpg ENSMUSG00000020287 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.643853282854191 0.643853282854191
Lig3 ENSMUSG00000020697 0.454600801949285 0.681901202923927 0.711034989117171 0.711034989117171 0.180293335960318 0.540880007880955
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Pole3 ENSMUSG00000028394 0.216214347033995 0.648643041101984 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Mutyh ENSMUSG00000028687 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152 0.926550375688041 0.926658283600152
Ogg1 ENSMUSG00000030271 0.213307944885796 0.639923834657388 0.706831781264721 0.706831781264721 0.509144723230069 0.706831781264721
Smug1 ENSMUSG00000036061 0.447265995733381 0.641867098978197 0.641867098978197 0.641867098978197 0.395196379647461 0.641867098978197
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Neil3 ENSMUSG00000039396 0.782117202022501 1 1 1 0.255901190956604 0.767703572869812
Nthl1 ENSMUSG00000041429 0.78148726569172 1 0.643853282854191 1 1 1
Hmgb1 ENSMUSG00000066551 0.120545895661627 0.180818843492441 0.010906560635693 0.032719681907079 0.295581119060361 0.295581119060361

Ubiquitin mediated proteolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Aire ENSMUSG00000000731 0.383124961266744 0.774871910813158 0.774871910813158 0.774871910813158 0.704879596572201 0.774871910813158
Fancl ENSMUSG00000004018 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.148772260628989 0.446316781886968
Ube2m ENSMUSG00000005575 0.456305241393103 0.456305241393103 0.180293335960318 0.449023590082343 0.299349060054895 0.449023590082343
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Fbxo4 ENSMUSG00000022184 0.252920381501207 0.598244634262948 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Birc6 ENSMUSG00000024073 0.119631084167592 0.358893252502775 0.853801250889739 0.926441990075769 0.926441990075769 0.926441990075769
Cul2 ENSMUSG00000024231 0.711650020253571 0.711650020253571 0.177853449259986 0.533560347779958 0.643853282854191 0.711650020253571
Nedd4l ENSMUSG00000024589 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155 0.21549027811633 0.64647083434899
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Ube2k ENSMUSG00000029203 0.0168921052924601 0.0506763158773803 0.578113371816017 0.867170057724026 0.926550375688041 0.926550375688041
Rchy1 ENSMUSG00000029397 0.454942951775341 1 0.711854160331342 1 1 1
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Anapc13 ENSMUSG00000035048 0.0451153644990945 0.135346093497283 0.577829325134931 0.643853282854191 0.643853282854191 0.643853282854191
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Rnf7 ENSMUSG00000051234 0.575536202757516 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Uba2 ENSMUSG00000052997 0.514934023620344 1 1 1 0.926333123228344 1
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Birc2 ENSMUSG00000057367 0.853801250889739 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Ube2e2 ENSMUSG00000058317 0.399548817627028 0.577829325134931 0.577829325134931 0.577829325134931 0.399548817627028 0.577829325134931
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Nucleotide excision repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Pole3 ENSMUSG00000028394 0.216214347033995 0.648643041101984 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Rad23b ENSMUSG00000028426 0.0743693776059063 0.223108132817719 0.455625354715449 0.576973746230334 0.576973746230334 0.576973746230334
Rpa2 ENSMUSG00000028884 0.120545895661628 0.361637686984883 0.711240436189781 0.711240436189781 0.300095920620218 0.450143880930327
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1

Mismatch repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Rpa2 ENSMUSG00000028884 0.120545895661628 0.361637686984883 0.711240436189781 0.711240436189781 0.300095920620218 0.450143880930327
Ssbp1 ENSMUSG00000029911 0.853480389728993 0.853480389728993 0.710208797518812 0.853480389728993 0.711650020253571 0.853480389728993
Mlh1 ENSMUSG00000032498 0.0413659913978561 0.124097974193568 0.297848640636702 0.446772960955053 1 1
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582

Cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Myc ENSMUSG00000022346 0.34837756124189 0.769540304784424 0.513026869856283 0.769540304784424 0.853801250889739 0.853801250889739
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Crebbp ENSMUSG00000022521 0.0969812105731562 0.175777610154895 0.117185073436597 0.175777610154895 0.712057867818062 0.712057867818062
Prkdc ENSMUSG00000022672 0.853801250889739 0.853801250889739 0.572616808177226 0.853801250889739 0.347639524025037 0.853801250889739
Pkmyt1 ENSMUSG00000023908 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.148772260628989 0.446316781886968
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Cdc7 ENSMUSG00000029283 0.853694531487825 0.853694531487825 0.398829756175299 0.598244634262948 0.347639524025037 0.598244634262948
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Orc6 ENSMUSG00000031697 0.575824878403157 0.575824878403157 0.450444934184774 0.575824878403157 0.295581119060361 0.575824878403157
Atr ENSMUSG00000032409 0.449391287230098 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Cdc14b ENSMUSG00000033102 0.177153312234059 0.531459936702178 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Anapc13 ENSMUSG00000035048 0.0451153644990945 0.135346093497283 0.577829325134931 0.643853282854191 0.643853282854191 0.643853282854191
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544

DNA replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Rnaseh1 ENSMUSG00000020630 0.299349060054895 0.643853282854191 0.643853282854191 0.643853282854191 0.638310022345193 0.643853282854191
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Pole3 ENSMUSG00000028394 0.216214347033995 0.648643041101984 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Rpa2 ENSMUSG00000028884 0.120545895661628 0.361637686984883 0.711240436189781 0.711240436189781 0.300095920620218 0.450143880930327
Ssbp1 ENSMUSG00000029911 0.853480389728993 0.853480389728993 0.710208797518812 0.853480389728993 0.711650020253571 0.853480389728993
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Rnaseh2a ENSMUSG00000052926 0.926658283600152 1 0.514934023620345 1 1 1

Fanconi anemia pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Fancl ENSMUSG00000004018 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.148772260628989 0.446316781886968
Fancc ENSMUSG00000021461 0.455965611639471 0.576973746230334 0.340887582990546 0.576973746230334 0.576973746230334 0.576973746230334
Top3b ENSMUSG00000022779 0.216214347033995 0.648643041101985 0.711650020253571 0.926658283600152 0.926658283600152 0.926658283600152
Telo2 ENSMUSG00000024170 0.706616781330066 1 1 1 0.779888212132595 1
Mus81 ENSMUSG00000024906 0.0936419271039908 0.280925781311972 0.711034989117171 0.711034989117171 0.710208797518812 0.711034989117171
Fancg ENSMUSG00000028453 0.511742979522636 0.710208797518812 0.710208797518812 0.710208797518812 0.072378961026407 0.217136883079221
Rpa2 ENSMUSG00000028884 0.120545895661628 0.361637686984883 0.711240436189781 0.711240436189781 0.300095920620218 0.450143880930327
Atr ENSMUSG00000032409 0.449391287230098 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Mlh1 ENSMUSG00000032498 0.0413659913978561 0.124097974193568 0.297848640636702 0.446772960955053 1 1
Slx4 ENSMUSG00000039738 0.45596561163947 0.45596561163947 0.0743693776059065 0.223108132817719 0.345037391052887 0.45596561163947
Palb2 ENSMUSG00000044702 0.853801250889739 1 0.926550375688041 1 1 1

RNA polymerase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Polr1b ENSMUSG00000027395 0.01710279005982 0.0513083701794599 0.293293089483362 0.439939634225043 0.852832278580641 0.852832278580641
Polr3e ENSMUSG00000030880 0.575536202757516 0.643359829732651 0.299349060054895 0.643359829732651 0.643359829732651 0.643359829732651
Znrd1 ENSMUSG00000036315 0.578113371816017 0.711854160331342 0.577829325134931 0.711854160331342 0.711854160331342 0.711854160331342
Polr2j ENSMUSG00000039771 0.575536202757516 0.865889271386954 0.926441990075769 0.926441990075769 0.577259514257969 0.865889271386954
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781

SRP-dependent cotranslational protein targeting to membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Srp14 ENSMUSG00000009549 0.7802108304765 0.852832278580641 0.454600801949285 0.852832278580641 0.852832278580641 0.852832278580641
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Formation of a pool of free 40S subunits

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

L13a-mediated translational silencing of Ceruloplasmin expression

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Eukaryotic Translation Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Eif2b1 ENSMUSG00000029388 0.711854160331342 0.711854160331342 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Cap-dependent Translation Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Eif2b1 ENSMUSG00000029388 0.711854160331342 0.711854160331342 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

GTP hydrolysis and joining of the 60S ribosomal subunit

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Magoh ENSMUSG00000028609 0.92622377157404 0.92622377157404 0.710208797518812 0.92622377157404 0.710208797518812 0.92622377157404
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Smg6 ENSMUSG00000038290 0.575536202757516 1 1 1 0.848399006995053 1
Upf3a ENSMUSG00000038398 0.0284675001636595 0.0427012502454892 0.00153425095635555 0.00460275286906665 0.711240436189781 0.711240436189781
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Smg7 ENSMUSG00000042772 0.255901190956604 0.383851786434905 0.216214347033995 0.383851786434905 0.78180291566155 0.78180291566155
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Nonsense-Mediated Decay (NMD)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Magoh ENSMUSG00000028609 0.92622377157404 0.92622377157404 0.710208797518812 0.92622377157404 0.710208797518812 0.92622377157404
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Smg6 ENSMUSG00000038290 0.575536202757516 1 1 1 0.848399006995053 1
Upf3a ENSMUSG00000038398 0.0284675001636595 0.0427012502454892 0.00153425095635555 0.00460275286906665 0.711240436189781 0.711240436189781
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Smg7 ENSMUSG00000042772 0.255901190956604 0.383851786434905 0.216214347033995 0.383851786434905 0.78180291566155 0.78180291566155
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Mrpl49 ENSMUSG00000007338 0.853049270252403 0.853049270252403 0.0575107614292585 0.172532284287776 0.576973746230334 0.853049270252403
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Srp14 ENSMUSG00000009549 0.7802108304765 0.852832278580641 0.454600801949285 0.852832278580641 0.852832278580641 0.852832278580641
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Mrpl52 ENSMUSG00000010406 0.147458757705095 0.442376273115284 1 1 0.572616808177226 0.85892521226584
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Ict1 ENSMUSG00000018858 0.454942951775341 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Mrpl39 ENSMUSG00000022889 0.00289311433957183 0.00867934301871548 0.452880492349546 0.452880492349546 0.299349060054895 0.449023590082343
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Eef1b2 ENSMUSG00000025967 0.256271555563967 0.38440733334595 0.17924968721805 0.38440733334595 0.514934023620345 0.514934023620345
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Eif2b1 ENSMUSG00000029388 0.711854160331342 0.711854160331342 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773
Mrpl51 ENSMUSG00000030335 0.575824878403157 0.863737317604735 0.216214347033995 0.648643041101984 1 1
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Eef1a1 ENSMUSG00000037742 0.926550375688041 0.926550375688041 0.395928178642446 0.926550375688041 0.853801250889739 0.926550375688041
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Mrps28 ENSMUSG00000040269 0.454942951775341 0.924405146515181 0.924405146515181 0.924405146515181 0.635703516568382 0.924405146515181
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Chchd1 ENSMUSG00000063787 0.78180291566155 0.926333123228344 0.400265374208515 0.926333123228344 0.926333123228344 0.926333123228344
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Dap3 ENSMUSG00000068921 1 1 0.0930846407079412 0.279253922123823 0.514934023620345 0.772401035430517
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

rRNA processing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C1d ENSMUSG00000000581 1 1 0.115651627788147 0.346954883364442 0.455625354715448 0.683438032073173
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Nob1 ENSMUSG00000003848 0.711240436189781 0.853694531487825 0.852832278580641 0.853694531487825 0.853694531487825 0.853694531487825
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Emg1 ENSMUSG00000004268 0.576973746230334 0.865460619345501 1 1 0.454600801949285 0.865460619345501
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Nol11 ENSMUSG00000018433 0.453225835454266 0.9255572759333 0.9255572759333 0.9255572759333 0.853801250889739 0.9255572759333
Pes1 ENSMUSG00000020430 0.454600801949285 0.454600801949285 0.214037080764326 0.321055621146488 0.0334587898203823 0.100376369461147
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Fcf1 ENSMUSG00000021243 0.78180291566155 1 1 1 0.852940894477647 1
Riok3 ENSMUSG00000024404 0.926604389137101 0.926604389137101 0.398469281729516 0.679838753181399 0.453225835454266 0.679838753181399
Rpp21 ENSMUSG00000024446 0.926003599371282 0.926003599371282 0.845463210524231 0.926003599371282 0.384672302267076 0.926003599371282
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rcl1 ENSMUSG00000024785 0.926333123228344 0.926333123228344 0.513665062682276 0.926333123228344 0.852832278580641 0.926333123228344
Exosc7 ENSMUSG00000025785 0.78180291566155 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Exosc8 ENSMUSG00000027752 1 1 0.926658283600152 1 0.297848640636702 0.893545921910107
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Imp3 ENSMUSG00000032288 0.456305241393103 0.640355507848752 0.214037080764326 0.640355507848752 0.640355507848752 0.640355507848752
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rrp9 ENSMUSG00000041506 0.705968934865368 0.705968934865368 0.452880492349546 0.679320738524319 0.0969812105731562 0.290943631719469
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Gnl3 ENSMUSG00000042354 0.641867098978198 0.926441990075769 0.348377561241889 0.926441990075769 0.926441990075769 0.926441990075769
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Ddx49 ENSMUSG00000057788 0.781170242226513 0.853372965654504 0.399548817627028 0.853372965654504 0.853372965654504 0.853372965654504
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Nhp2l1 ENSMUSG00000063480 0.711854160331342 0.926658283600152 0.342026805366747 0.926658283600152 0.926658283600152 0.926658283600152
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

rRNA processing in the nucleus and cytosol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C1d ENSMUSG00000000581 1 1 0.115651627788147 0.346954883364442 0.455625354715448 0.683438032073173
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Nob1 ENSMUSG00000003848 0.711240436189781 0.853694531487825 0.852832278580641 0.853694531487825 0.853694531487825 0.853694531487825
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Emg1 ENSMUSG00000004268 0.576973746230334 0.865460619345501 1 1 0.454600801949285 0.865460619345501
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Nol11 ENSMUSG00000018433 0.453225835454266 0.9255572759333 0.9255572759333 0.9255572759333 0.853801250889739 0.9255572759333
Pes1 ENSMUSG00000020430 0.454600801949285 0.454600801949285 0.214037080764326 0.321055621146488 0.0334587898203823 0.100376369461147
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Fcf1 ENSMUSG00000021243 0.78180291566155 1 1 1 0.852940894477647 1
Riok3 ENSMUSG00000024404 0.926604389137101 0.926604389137101 0.398469281729516 0.679838753181399 0.453225835454266 0.679838753181399
Rpp21 ENSMUSG00000024446 0.926003599371282 0.926003599371282 0.845463210524231 0.926003599371282 0.384672302267076 0.926003599371282
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rcl1 ENSMUSG00000024785 0.926333123228344 0.926333123228344 0.513665062682276 0.926333123228344 0.852832278580641 0.926333123228344
Exosc7 ENSMUSG00000025785 0.78180291566155 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Exosc8 ENSMUSG00000027752 1 1 0.926658283600152 1 0.297848640636702 0.893545921910107
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Imp3 ENSMUSG00000032288 0.456305241393103 0.640355507848752 0.214037080764326 0.640355507848752 0.640355507848752 0.640355507848752
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rrp9 ENSMUSG00000041506 0.705968934865368 0.705968934865368 0.452880492349546 0.679320738524319 0.0969812105731562 0.290943631719469
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Gnl3 ENSMUSG00000042354 0.641867098978198 0.926441990075769 0.348377561241889 0.926441990075769 0.926441990075769 0.926441990075769
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Ddx49 ENSMUSG00000057788 0.781170242226513 0.853372965654504 0.399548817627028 0.853372965654504 0.853372965654504 0.853372965654504
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Nhp2l1 ENSMUSG00000063480 0.711854160331342 0.926658283600152 0.342026805366747 0.926658283600152 0.926658283600152 0.926658283600152
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Major pathway of rRNA processing in the nucleolus and cytosol

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C1d ENSMUSG00000000581 1 1 0.115651627788147 0.346954883364442 0.455625354715448 0.683438032073173
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Nob1 ENSMUSG00000003848 0.711240436189781 0.853694531487825 0.852832278580641 0.853694531487825 0.853694531487825 0.853694531487825
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Emg1 ENSMUSG00000004268 0.576973746230334 0.865460619345501 1 1 0.454600801949285 0.865460619345501
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Nol11 ENSMUSG00000018433 0.453225835454266 0.9255572759333 0.9255572759333 0.9255572759333 0.853801250889739 0.9255572759333
Pes1 ENSMUSG00000020430 0.454600801949285 0.454600801949285 0.214037080764326 0.321055621146488 0.0334587898203823 0.100376369461147
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Fcf1 ENSMUSG00000021243 0.78180291566155 1 1 1 0.852940894477647 1
Riok3 ENSMUSG00000024404 0.926604389137101 0.926604389137101 0.398469281729516 0.679838753181399 0.453225835454266 0.679838753181399
Rpp21 ENSMUSG00000024446 0.926003599371282 0.926003599371282 0.845463210524231 0.926003599371282 0.384672302267076 0.926003599371282
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rcl1 ENSMUSG00000024785 0.926333123228344 0.926333123228344 0.513665062682276 0.926333123228344 0.852832278580641 0.926333123228344
Exosc7 ENSMUSG00000025785 0.78180291566155 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Exosc8 ENSMUSG00000027752 1 1 0.926658283600152 1 0.297848640636702 0.893545921910107
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Imp3 ENSMUSG00000032288 0.456305241393103 0.640355507848752 0.214037080764326 0.640355507848752 0.640355507848752 0.640355507848752
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rrp9 ENSMUSG00000041506 0.705968934865368 0.705968934865368 0.452880492349546 0.679320738524319 0.0969812105731562 0.290943631719469
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Gnl3 ENSMUSG00000042354 0.641867098978198 0.926441990075769 0.348377561241889 0.926441990075769 0.926441990075769 0.926441990075769
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Ddx49 ENSMUSG00000057788 0.781170242226513 0.853372965654504 0.399548817627028 0.853372965654504 0.853372965654504 0.853372965654504
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Nhp2l1 ENSMUSG00000063480 0.711854160331342 0.926658283600152 0.342026805366747 0.926658283600152 0.926658283600152 0.926658283600152
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
C1d ENSMUSG00000000581 1 1 0.115651627788147 0.346954883364442 0.455625354715448 0.683438032073173
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Nob1 ENSMUSG00000003848 0.711240436189781 0.853694531487825 0.852832278580641 0.853694531487825 0.853694531487825 0.853694531487825
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Emg1 ENSMUSG00000004268 0.576973746230334 0.865460619345501 1 1 0.454600801949285 0.865460619345501
Ddx39 ENSMUSG00000005481 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.578113371816017 0.853801250889739
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Nxf1 ENSMUSG00000010097 0.455625354715448 0.683438032073173 0.711650020253571 0.711650020253571 0.346527959006435 0.683438032073173
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Nol11 ENSMUSG00000018433 0.453225835454266 0.9255572759333 0.9255572759333 0.9255572759333 0.853801250889739 0.9255572759333
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Hbs1l ENSMUSG00000019977 0.249907451332337 0.374861176998506 0.171503747555202 0.374861176998506 0.78180291566155 0.78180291566155
Pes1 ENSMUSG00000020430 0.454600801949285 0.454600801949285 0.214037080764326 0.321055621146488 0.0334587898203823 0.100376369461147
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Zfp36l1 ENSMUSG00000021127 0.511097249598474 0.57113445032749 0.45596561163947 0.57113445032749 0.57113445032749 0.57113445032749
Fcf1 ENSMUSG00000021243 0.78180291566155 1 1 1 0.852940894477647 1
Smn1 ENSMUSG00000021645 0.643359829732651 0.926550375688041 0.454600801949285 0.926550375688041 0.926550375688041 0.926550375688041
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Riok3 ENSMUSG00000024404 0.926604389137101 0.926604389137101 0.398469281729516 0.679838753181399 0.453225835454266 0.679838753181399
Rpp21 ENSMUSG00000024446 0.926003599371282 0.926003599371282 0.845463210524231 0.926003599371282 0.384672302267076 0.926003599371282
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Rcl1 ENSMUSG00000024785 0.926333123228344 0.926333123228344 0.513665062682276 0.926333123228344 0.852832278580641 0.926333123228344
Exosc7 ENSMUSG00000025785 0.78180291566155 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Ppil3 ENSMUSG00000026035 1 1 0.400265374208515 1 0.712057867818062 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Clp1 ENSMUSG00000027079 0.577259514257969 0.865889271386954 0.577259514257969 0.865889271386954 0.92622377157404 0.92622377157404
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Exosc8 ENSMUSG00000027752 1 1 0.926658283600152 1 0.297848640636702 0.893545921910107
Plrg1 ENSMUSG00000027998 0.712057867818062 0.779888212132595 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Magoh ENSMUSG00000028609 0.92622377157404 0.92622377157404 0.710208797518812 0.92622377157404 0.710208797518812 0.92622377157404
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Syf2 ENSMUSG00000028821 0.21549027811633 0.593892267963669 0.395928178642446 0.593892267963669 0.706831781264721 0.706831781264721
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Srsf9 ENSMUSG00000029538 0.214764523938594 0.644293571815781 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Sec13 ENSMUSG00000030298 0.782117202022501 0.853372965654504 0.643853282854191 0.853372965654504 0.853372965654504 0.853372965654504
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Snrpa1 ENSMUSG00000030512 0.453225835454266 0.679838753181399 0.293293089483362 0.679838753181399 0.926550375688041 0.926550375688041
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Dcps ENSMUSG00000032040 0.449391287230099 0.926003599371282 0.926003599371282 0.926003599371282 0.708534948098331 0.926003599371282
Imp3 ENSMUSG00000032288 0.456305241393103 0.640355507848752 0.214037080764326 0.640355507848752 0.640355507848752 0.640355507848752
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Nup37 ENSMUSG00000035351 0.853801250889739 0.853801250889739 0.511742979522636 0.853801250889739 0.853372965654504 0.853801250889739
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Nxt1 ENSMUSG00000036992 0.926333123228344 0.926333123228344 0.710416009055326 0.926333123228344 0.57466664340579 0.926333123228344
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Smg6 ENSMUSG00000038290 0.575536202757516 1 1 1 0.848399006995053 1
Upf3a ENSMUSG00000038398 0.0284675001636595 0.0427012502454892 0.00153425095635555 0.00460275286906665 0.711240436189781 0.711240436189781
Nup205 ENSMUSG00000038759 0.214037080764326 0.642111242292977 0.712057867818062 0.853694531487825 0.853694531487825 0.853694531487825
Cnot4 ENSMUSG00000038784 0.0579478375430677 0.173843512629203 0.782117202022501 0.782117202022501 0.398829756175299 0.598244634262948
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Hnrnpul1 ENSMUSG00000040725 0.852940894477647 0.926333123228344 0.17924968721805 0.537749061654149 0.926333123228344 0.926333123228344
Snrnp25 ENSMUSG00000040767 0.643853282854191 0.853372965654504 0.211110344399808 0.633331033199424 0.853372965654504 0.853372965654504
Snrpd2 ENSMUSG00000040824 0.299349060054895 0.683948417459205 0.45596561163947 0.683948417459205 0.926550375688041 0.926550375688041
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rrp9 ENSMUSG00000041506 0.705968934865368 0.705968934865368 0.452880492349546 0.679320738524319 0.0969812105731562 0.290943631719469
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Gnl3 ENSMUSG00000042354 0.641867098978198 0.926441990075769 0.348377561241889 0.926441990075769 0.926441990075769 0.926441990075769
Smg7 ENSMUSG00000042772 0.255901190956604 0.383851786434905 0.216214347033995 0.383851786434905 0.78180291566155 0.78180291566155
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Hnrnpa1 ENSMUSG00000046434 0.514300775319626 0.577829325134931 0.456305241393103 0.577829325134931 0.577829325134931 0.577829325134931
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Pom121 ENSMUSG00000053293 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Thoc7 ENSMUSG00000053453 0.514300775319626 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Cnot10 ENSMUSG00000056167 0.400265374208515 0.667674500503417 0.445116333668945 0.667674500503417 0.850151080737202 0.850151080737202
Snrpg ENSMUSG00000057278 0.294820734456232 0.512471536058169 0.341647690705446 0.512471536058169 0.513026869856283 0.513026869856283
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Ddx49 ENSMUSG00000057788 0.781170242226513 0.853372965654504 0.399548817627028 0.853372965654504 0.853372965654504 0.853372965654504
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Nhp2l1 ENSMUSG00000063480 0.711854160331342 0.926658283600152 0.342026805366747 0.926658283600152 0.926658283600152 0.926658283600152
Prpf38a ENSMUSG00000063800 0.577829325134931 0.577829325134931 0.395928178642446 0.577829325134931 0.452880492349546 0.577829325134931
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Srsf3 ENSMUSG00000071172 0.926658283600152 0.926658283600152 0.780851835278818 0.926658283600152 0.710416009055326 0.926658283600152
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
U2af1l4 ENSMUSG00000078765 0.0566379395854602 0.169913818756381 0.148772260628989 0.223158390943483 0.781170242226513 0.781170242226513
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Snrpe ENSMUSG00000090553 0.78180291566155 0.78180291566155 0.399548817627028 0.78180291566155 0.78180291566155 0.78180291566155
Hspa1b ENSMUSG00000090877 0.214037080764326 0.642111242292977 0.852832278580641 0.852832278580641 0.643853282854191 0.852832278580641
Lsm5 ENSMUSG00000091625 0.926550375688041 0.926550375688041 0.78148726569172 0.926550375688041 0.926441990075769 0.926550375688041
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Timmdc1 ENSMUSG00000002846 0.852832278580641 0.852832278580641 0.119631084167591 0.358893252502774 0.852832278580641 0.852832278580641
Etfb ENSMUSG00000004610 0.214037080764326 0.518116419532656 0.345410946355104 0.518116419532656 0.711650020253571 0.711650020253571
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Slc25a27 ENSMUSG00000023912 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342 0.347639524025037 0.711854160331342
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Acad9 ENSMUSG00000027710 0.711034989117171 0.782117202022501 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Etfa ENSMUSG00000032314 0.346156228791382 0.850036160745954 0.780049698709835 0.850036160745954 0.850036160745954 0.850036160745954
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Nubpl ENSMUSG00000035142 0.710208797518812 0.710208797518812 0.511742979522636 0.710208797518812 0.710001140920767 0.710208797518812
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Timmdc1 ENSMUSG00000002846 0.852832278580641 0.852832278580641 0.119631084167591 0.358893252502774 0.852832278580641 0.852832278580641
Etfb ENSMUSG00000004610 0.214037080764326 0.518116419532656 0.345410946355104 0.518116419532656 0.711650020253571 0.711650020253571
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Acad9 ENSMUSG00000027710 0.711034989117171 0.782117202022501 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Etfa ENSMUSG00000032314 0.346156228791382 0.850036160745954 0.780049698709835 0.850036160745954 0.850036160745954 0.850036160745954
Nubpl ENSMUSG00000035142 0.710208797518812 0.710208797518812 0.511742979522636 0.710208797518812 0.710001140920767 0.710208797518812
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Translation initiation complex formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034

Formation of the ternary complex, and subsequently, the 43S complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034

The citric acid (TCA) cycle and respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Timmdc1 ENSMUSG00000002846 0.852832278580641 0.852832278580641 0.119631084167591 0.358893252502774 0.852832278580641 0.852832278580641
Etfb ENSMUSG00000004610 0.214037080764326 0.518116419532656 0.345410946355104 0.518116419532656 0.711650020253571 0.711650020253571
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Gstz1 ENSMUSG00000021033 0.455625354715448 0.851061028660105 0.851061028660105 0.851061028660105 0.7802108304765 0.851061028660105
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Slc25a27 ENSMUSG00000023912 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342 0.347639524025037 0.711854160331342
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Fh1 ENSMUSG00000026526 0.853372965654504 0.853372965654504 0.643359829732651 0.853372965654504 0.641867098978198 0.853372965654504
Idh3b ENSMUSG00000027406 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.399548817627028 0.781170242226513
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Acad9 ENSMUSG00000027710 0.711034989117171 0.782117202022501 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Etfa ENSMUSG00000032314 0.346156228791382 0.850036160745954 0.780049698709835 0.850036160745954 0.850036160745954 0.850036160745954
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Nubpl ENSMUSG00000035142 0.710208797518812 0.710208797518812 0.511742979522636 0.710208797518812 0.710001140920767 0.710208797518812
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Fahd1 ENSMUSG00000045316 0.926003599371281 0.926003599371281 0.708534948098331 0.926003599371281 0.640861491578951 0.926003599371281
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Suclg1 ENSMUSG00000052738 0.643359829732651 0.643359829732651 0.511742979522636 0.643359829732651 0.642864324224729 0.643359829732651
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034

Ribosomal scanning and start codon recognition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034

Complex I biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Timmdc1 ENSMUSG00000002846 0.852832278580641 0.852832278580641 0.119631084167591 0.358893252502774 0.852832278580641 0.852832278580641
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Acad9 ENSMUSG00000027710 0.711034989117171 0.782117202022501 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Nubpl ENSMUSG00000035142 0.710208797518812 0.710208797518812 0.511742979522636 0.710208797518812 0.710001140920767 0.710208797518812
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894

Metabolism of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.397384062266614 0.577829325134931 0.577829325134931 0.577829325134931 0.348008842235184 0.577829325134931
Galnt1 ENSMUSG00000000420 0.853372965654504 0.926550375688041 0.926550375688041 0.926550375688041 0.254414773803597 0.763244321410791
Cct3 ENSMUSG00000001416 0.346899083932133 0.513026869856283 0.453225835454266 0.513026869856283 0.513026869856283 0.513026869856283
Rab8a ENSMUSG00000003037 0.447265995733381 0.563485358844814 0.255901190956604 0.563485358844814 0.563485358844814 0.563485358844814
Rps11 ENSMUSG00000003429 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343 0.853801250889739 0.853801250889739
Rpl8 ENSMUSG00000003970 0.249907451332337 0.51304020805012 0.342026805366747 0.51304020805012 0.852504981253341 0.852504981253341
Etfb ENSMUSG00000004610 0.214037080764326 0.518116419532656 0.345410946355104 0.518116419532656 0.711650020253571 0.711650020253571
Ube2m ENSMUSG00000005575 0.456305241393103 0.456305241393103 0.180293335960318 0.449023590082343 0.299349060054895 0.449023590082343
Apoa2 ENSMUSG00000005681 0.0936419271039908 0.280925781311972 0.7802108304765 0.7802108304765 0.643359829732651 0.7802108304765
Mrpl49 ENSMUSG00000007338 0.853049270252403 0.853049270252403 0.0575107614292585 0.172532284287776 0.576973746230334 0.853049270252403
Rplp1 ENSMUSG00000007892 0.299349060054895 0.449023590082343 0.148115998140416 0.444347994421247 1 1
Fbxw9 ENSMUSG00000008167 0.926003599371281 0.926003599371281 0.926003599371281 0.926003599371281 0.399548817627028 0.926003599371281
Rps18 ENSMUSG00000008668 0.397384062266614 0.596076093399921 0.299349060054895 0.596076093399921 1 1
Rpl10 ENSMUSG00000008682 0.0936419271039908 0.280925781311972 0.513665062682276 0.641867098978197 0.641867098978197 0.641867098978197
Rps15a ENSMUSG00000008683 0.514934023620345 0.772401035430517 0.295581119060361 0.772401035430517 0.926003599371281 0.926003599371281
Vdac3 ENSMUSG00000008892 1 1 0.174692232033629 0.524076696100888 0.711854160331342 1
Srp14 ENSMUSG00000009549 0.7802108304765 0.852832278580641 0.454600801949285 0.852832278580641 0.852832278580641 0.852832278580641
Rps25 ENSMUSG00000009927 0.177853449259986 0.533560347779958 0.398108175780842 0.597162263671263 0.853372965654504 0.853372965654504
Nedd8 ENSMUSG00000010376 0.926003599371282 0.926003599371282 0.0953125666339397 0.285937699901819 0.640861491578951 0.926003599371282
Mrpl52 ENSMUSG00000010406 0.147458757705095 0.442376273115284 1 1 0.572616808177226 0.85892521226584
Pigyl ENSMUSG00000010607 0.148115998140415 0.444347994421246 0.572616808177226 0.85117361048289 0.85117361048289 0.85117361048289
Rpl15 ENSMUSG00000012405 0.643359829732651 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Csf1 ENSMUSG00000014599 0.853372965654504 0.853372965654504 0.346527959006435 0.519791938509652 0.297848640636702 0.519791938509652
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Trappc2l ENSMUSG00000015013 0.348008842235184 0.522013263352777 0.179945789077372 0.522013263352777 0.642366752097095 0.642366752097095
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Rpl19 ENSMUSG00000017404 0.299349060054895 0.781170242226513 0.711650020253571 0.781170242226513 0.781170242226513 0.781170242226513
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Adora2b ENSMUSG00000018500 0.0958690133561599 0.211844580334808 0.17610058307789 0.211844580334808 0.211844580334808 0.211844580334808
Cog1 ENSMUSG00000018661 0.01710279005982 0.0513083701794599 0.513665062682276 0.770497594023414 1 1
Ict1 ENSMUSG00000018858 0.454942951775341 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Sar1b ENSMUSG00000020386 0.711240436189781 0.711240436189781 0.254787123615605 0.711240436189781 0.638824656785692 0.711240436189781
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Slc30a5 ENSMUSG00000021629 0.398829756175299 0.711034989117171 0.577829325134931 0.711034989117171 0.711034989117171 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Ngly1 ENSMUSG00000021785 0.711650020253571 0.926333123228344 0.452880492349546 0.926333123228344 0.926333123228344 0.926333123228344
Dph3 ENSMUSG00000021905 0.853694531487825 0.926333123228344 0.643853282854191 0.926333123228344 0.926333123228344 0.926333123228344
N6amt2 ENSMUSG00000021951 0.774176834800231 0.846584006881321 0.144157978128026 0.432473934384078 0.846584006881321 0.846584006881321
Fbxo4 ENSMUSG00000022184 0.252920381501207 0.598244634262948 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Dcaf11 ENSMUSG00000022214 0.926333123228344 1 1 1 0.780851835278817 1
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Myc ENSMUSG00000022346 0.34837756124189 0.769540304784424 0.513026869856283 0.769540304784424 0.853801250889739 0.853801250889739
Ttll8 ENSMUSG00000022388 0.926496242814507 0.926496242814507 0.397021051130447 0.681901202923927 0.454600801949285 0.681901202923927
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Tsta3 ENSMUSG00000022570 0.447621891168214 0.67143283675232 0.17750354896016 0.532510646880481 1 1
Prkdc ENSMUSG00000022672 0.853801250889739 0.853801250889739 0.572616808177226 0.853801250889739 0.347639524025037 0.853801250889739
St3gal6 ENSMUSG00000022747 0.456305241393104 0.684457862089656 0.252920381501207 0.684457862089656 0.707899741868332 0.707899741868332
Mrpl39 ENSMUSG00000022889 0.00289311433957183 0.00867934301871548 0.452880492349546 0.452880492349546 0.299349060054895 0.449023590082343
Pigp ENSMUSG00000022940 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Nus1 ENSMUSG00000023068 0.643853282854191 0.643853282854191 0.0441715176243983 0.132514552873195 0.454600801949285 0.643853282854191
Pigx ENSMUSG00000023791 0.853480389728993 0.853480389728993 0.708745765211584 0.853480389728993 0.21549027811633 0.64647083434899
Pigf ENSMUSG00000024145 0.45596561163947 0.683948417459205 0.853801250889739 0.853801250889739 0.0443599545252853 0.133079863575856
Mcfd2 ENSMUSG00000024150 0.216214347033995 0.324321520550992 0.209636747299872 0.324321520550992 0.514300775319626 0.514300775319626
Cul2 ENSMUSG00000024231 0.711650020253571 0.711650020253571 0.177853449259986 0.533560347779958 0.643853282854191 0.711650020253571
Wac ENSMUSG00000024283 0.00755778364492931 0.0226733509347879 0.121155015244363 0.181732522866545 0.514300775319626 0.514300775319626
Ring1 ENSMUSG00000024325 0.342026805366747 0.51304020805012 0.776243028387552 0.776243028387552 0.118714930081337 0.35614479024401
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Rps14 ENSMUSG00000024608 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.853801250889739 0.853801250889739
Uhrf2 ENSMUSG00000024817 0.453225835454266 0.576973746230334 0.576973746230334 0.576973746230334 0.453570536021945 0.576973746230334
Rce1 ENSMUSG00000024889 0.711240436189781 0.853694531487825 0.346527959006435 0.853694531487825 0.853694531487825 0.853694531487825
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Gbf1 ENSMUSG00000025224 0.711034989117171 0.711034989117171 0.243396309647536 0.442231101684348 0.294820734456232 0.442231101684348
Fuom ENSMUSG00000025466 0.299349060054895 0.7733472349452 0.782117202022501 0.782117202022501 0.5155648232968 0.7733472349452
Cbx8 ENSMUSG00000025578 0.0331400397096515 0.0497100595644772 0.00247508107184991 0.00742524321554974 0.782117202022501 0.782117202022501
Copg2 ENSMUSG00000025607 0.300095920620218 0.640355507848752 0.5155648232968 0.640355507848752 0.640355507848752 0.640355507848752
Shisa5 ENSMUSG00000025647 0.513665062682276 0.965779924281287 1 1 0.643853282854191 0.965779924281287
Fbxl16 ENSMUSG00000025738 0.926658283600152 0.926658283600152 0.852940894477647 0.926658283600152 0.852832278580641 0.926658283600152
Rpl14 ENSMUSG00000025794 0.578113371816017 0.78180291566155 0.177853449259986 0.533560347779959 0.78180291566155 0.78180291566155
Mettl21a ENSMUSG00000025956 0.00289311433957183 0.0086793430187155 0.346527959006435 0.519791938509652 0.853049270252403 0.853049270252403
Eef1b2 ENSMUSG00000025967 0.256271555563967 0.38440733334595 0.17924968721805 0.38440733334595 0.514934023620345 0.514934023620345
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Pigc ENSMUSG00000026698 0.853694531487825 0.853694531487825 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Dpm2 ENSMUSG00000026810 0.148772260628989 0.446316781886968 0.45596561163947 0.683948417459205 0.78148726569172 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Eif3m ENSMUSG00000027170 0.853694531487825 0.926550375688041 0.345037391052887 0.926550375688041 0.926550375688041 0.926550375688041
Fbn1 ENSMUSG00000027204 0.0389688840169855 0.116906652050956 0.502123862653891 0.502123862653891 0.255530331334266 0.383295497001398
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Chgb ENSMUSG00000027350 0.853372965654504 0.853372965654504 0.782117202022501 0.853372965654504 0.710416009055326 0.853372965654504
Cst3 ENSMUSG00000027447 0.01710279005982 0.0513083701794599 0.926658283600152 0.926658283600152 0.643853282854191 0.926658283600152
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Gnb4 ENSMUSG00000027669 0.300095920620218 0.852504981253341 0.852504981253341 0.852504981253341 0.778911768167544 0.852504981253341
Rps3a1 ENSMUSG00000028081 0.347639524025037 0.683948417459205 0.853372965654504 0.853372965654504 0.45596561163947 0.683948417459205
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Rps20 ENSMUSG00000028234 0.254414773803597 0.381622160705395 0.11993617140438 0.359808514213139 0.78180291566155 0.78180291566155
Slc35a1 ENSMUSG00000028293 1 1 0.400265374208515 0.600398061312773 0.348008842235184 0.600398061312773
Rad23b ENSMUSG00000028426 0.0743693776059063 0.223108132817719 0.455625354715449 0.576973746230334 0.576973746230334 0.576973746230334
Ptp4a2 ENSMUSG00000028788 0.511742979522636 0.640861491578951 0.17750354896016 0.53251064688048 0.640861491578951 0.640861491578951
Eif3i ENSMUSG00000028798 0.573498913947369 0.853694531487825 0.216214347033995 0.648643041101984 0.853694531487825 0.853694531487825
Rpl22 ENSMUSG00000028936 0.575536202757516 0.575536202757516 0.398108175780842 0.575536202757516 0.514300775319626 0.575536202757516
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Ube2k ENSMUSG00000029203 0.0168921052924601 0.0506763158773803 0.578113371816017 0.867170057724026 0.926550375688041 0.926550375688041
Sparcl1 ENSMUSG00000029309 0.643359829732651 0.643359829732651 0.345037391052887 0.599323226440542 0.399548817627028 0.599323226440542
Eif2b1 ENSMUSG00000029388 0.711854160331342 0.711854160331342 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773
Rab35 ENSMUSG00000029518 0.514934023620345 0.772401035430517 0.926550375688041 0.926550375688041 0.348008842235184 0.772401035430517
Usp12 ENSMUSG00000029640 0.399548817627028 0.599323226440542 0.255530331334266 0.599323226440542 0.710416009055326 0.710416009055326
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Rad52 ENSMUSG00000030166 0.0958690133561599 0.28760704006848 0.642864324224729 0.642864324224729 0.299349060054895 0.449023590082343
Ttll3 ENSMUSG00000030276 0.711240436189781 0.711240436189781 0.578113371816017 0.711240436189781 0.711034989117171 0.711240436189781
Sec13 ENSMUSG00000030298 0.782117202022501 0.853372965654504 0.643853282854191 0.853372965654504 0.853372965654504 0.853372965654504
Mrpl51 ENSMUSG00000030335 0.575824878403157 0.863737317604735 0.216214347033995 0.648643041101984 1 1
Rps3 ENSMUSG00000030744 0.179945789077372 0.539837367232116 0.398108175780842 0.597162263671263 0.926658283600152 0.926658283600152
Rps4x ENSMUSG00000031320 0.299349060054895 0.597162263671263 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gnao1 ENSMUSG00000031748 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Cog4 ENSMUSG00000031753 0.78148726569172 1 1 1 0.399548817627028 1
Cog2 ENSMUSG00000031979 1 1 0.926550375688041 1 0.455625354715449 1
Apoa1 ENSMUSG00000032083 0.50075242599667 0.751128638995005 1 1 0.291370537767947 0.751128638995005
Commd4 ENSMUSG00000032299 0.514300775319626 0.771451162979439 0.293293089483362 0.771451162979439 0.926333123228344 0.926333123228344
Rpsa ENSMUSG00000032518 0.348008842235184 0.7733472349452 0.852832278580641 0.852832278580641 0.5155648232968 0.7733472349452
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Gng11 ENSMUSG00000032766 0.0766111619812296 0.229833485943689 0.711034989117171 1 1 1
Fbxl8 ENSMUSG00000033313 0.178901132102685 0.268351698154027 0.175749000247038 0.268351698154027 0.926604389137101 0.926604389137101
Tpst1 ENSMUSG00000034118 0.148772260628989 0.223158390943484 0.148115998140416 0.223158390943484 0.853907737111068 0.853907737111068
Sec22a ENSMUSG00000034473 0.567513221841557 0.780851835278818 0.178901132102684 0.536703396308053 0.780851835278818 0.780851835278818
Rps29 ENSMUSG00000034892 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652 0.711650020253571 0.711650020253571
Sec31a ENSMUSG00000035325 0.399548817627028 0.573791743469336 0.120545895661628 0.361637686984883 0.573791743469336 0.573791743469336
Nup37 ENSMUSG00000035351 0.853801250889739 0.853801250889739 0.511742979522636 0.853801250889739 0.853372965654504 0.853801250889739
Mgat5 ENSMUSG00000036155 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.455625354715448 0.5155648232968
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Exoc1 ENSMUSG00000036435 0.926550375688041 0.926550375688041 0.78180291566155 0.926550375688041 0.142165951159432 0.426497853478296
Commd2 ENSMUSG00000036513 0.92589277149125 0.92589277149125 0.852504981253341 0.92589277149125 0.453225835454266 0.92589277149125
Alg5 ENSMUSG00000036632 0.853694531487825 0.853694531487825 0.709375484777034 0.853694531487825 0.252545530864481 0.757636592593443
Rps27l ENSMUSG00000036781 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.782117202022501 0.92622377157404
Amdhd2 ENSMUSG00000036820 0.0753654386865988 0.226096316059796 0.578113371816017 0.711034989117171 0.711034989117171 0.711034989117171
Man1c1 ENSMUSG00000037306 0.926658283600152 0.926658283600152 0.711650020253571 0.926658283600152 0.781170242226513 0.926658283600152
Rps16 ENSMUSG00000037563 0.148115998140416 0.378818296296721 0.252545530864481 0.378818296296721 0.926441990075769 0.926441990075769
Gnpnat1 ENSMUSG00000037722 0.21549027811633 0.323235417174495 0.0936419271039908 0.280925781311972 0.643359829732651 0.643359829732651
Eef1a1 ENSMUSG00000037742 0.926550375688041 0.926550375688041 0.395928178642446 0.926550375688041 0.853801250889739 0.926550375688041
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Kdm1b ENSMUSG00000038080 0.711854160331342 0.92622377157404 0.254414773803597 0.763244321410791 0.92622377157404 0.92622377157404
Nup205 ENSMUSG00000038759 0.214037080764326 0.642111242292977 0.712057867818062 0.853694531487825 0.853694531487825 0.853694531487825
Rpl12 ENSMUSG00000038900 0.853049270252403 0.926658283600152 0.780851835278818 0.926658283600152 0.926658283600152 0.926658283600152
Rps21 ENSMUSG00000039001 0.178901132102685 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Pigk ENSMUSG00000039047 0.0964252305385471 0.16283148250234 0.108554321668226 0.16283148250234 0.381566259882379 0.381566259882379
Rpl22l1 ENSMUSG00000039221 0.853907737111068 1 0.119936171404379 0.359808514213138 1 1
Mrps28 ENSMUSG00000040269 0.454942951775341 0.924405146515181 0.924405146515181 0.924405146515181 0.635703516568382 0.924405146515181
St8sia4 ENSMUSG00000040710 0.0936419271039908 0.280925781311972 0.781170242226513 0.781170242226513 0.710001140920767 0.781170242226513
Rps19 ENSMUSG00000040952 0.400265374208515 0.600398061312773 0.298599969973533 0.600398061312773 0.782117202022501 0.782117202022501
Rpl37 ENSMUSG00000041841 0.144820068500793 0.43446020550238 0.346899083932133 0.520348625898199 1 1
Dpm3 ENSMUSG00000042737 0.348008842235184 0.522013263352776 0.347639524025037 0.522013263352776 0.926550375688041 0.926550375688041
Eif3j2 ENSMUSG00000043424 0.00768144932639892 0.0230443479791968 0.18064054691103 0.270960820366546 0.926658283600152 0.926658283600152
Rpl7 ENSMUSG00000043716 0.711650020253571 0.711650020253571 0.641867098978198 0.711650020253571 0.643359829732651 0.711650020253571
Nrn1l ENSMUSG00000044287 0.0575107614292584 0.172532284287775 0.343537039781257 0.515305559671886 0.781170242226513 0.781170242226513
Rpl18a ENSMUSG00000045128 0.399548817627028 0.781170242226513 0.709375484777034 0.781170242226513 0.781170242226513 0.781170242226513
Pigw ENSMUSG00000045140 0.706616781330066 0.706616781330066 0.178901132102685 0.441659526834679 0.294439684556453 0.441659526834679
Ttll13 ENSMUSG00000045467 0.0439832496172287 0.131949748851686 0.347269605097055 0.347269605097055 0.173986036612497 0.260979054918745
Rpl37a ENSMUSG00000046330 0.255901190956604 0.383851786434906 0.254414773803597 0.383851786434906 0.92622377157404 0.92622377157404
Rpl27a ENSMUSG00000046364 0.640861491578951 0.640861491578951 0.348008842235184 0.640861491578951 0.578396848531894 0.640861491578951
Arsj ENSMUSG00000046561 0.0076814493263989 0.0230443479791967 0.116265430850263 0.174398146275395 0.711034989117171 0.711034989117171
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Rpl9 ENSMUSG00000047215 0.147458757705094 0.269918683616058 0.179945789077372 0.269918683616058 1 1
Hist1h2be ENSMUSG00000047246 0.711854160331342 0.711854160331342 0.148772260628989 0.446316781886968 0.711854160331342 0.711854160331342
Rps8 ENSMUSG00000047675 0.346899083932133 0.520348625898199 0.178901132102685 0.520348625898199 0.853801250889739 0.853801250889739
Dcun1d3 ENSMUSG00000048787 0.643853282854191 0.643853282854191 0.390750658104794 0.586125987157192 0.0741204440774082 0.222361332232225
Trappc1 ENSMUSG00000049299 0.450794830295118 0.643359829732651 0.643359829732651 0.643359829732651 0.456305241393103 0.643359829732651
Rps23 ENSMUSG00000049517 0.299349060054895 0.771451162979439 0.926333123228344 0.926333123228344 0.514300775319626 0.771451162979439
Rpl36al ENSMUSG00000049751 0.575824878403157 0.852832278580641 0.347639524025037 0.852832278580641 0.852832278580641 0.852832278580641
Mettl21d ENSMUSG00000049882 0.643853282854191 0.780851835278818 0.513665062682276 0.780851835278818 0.780851835278818 0.780851835278818
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Gm9846 ENSMUSG00000050621 0.256271555563966 0.384407333345949 0.255530331334266 0.384407333345949 0.853801250889739 0.853801250889739
Rnf7 ENSMUSG00000051234 0.575536202757516 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Commd1 ENSMUSG00000051355 0.297848640636702 0.521459286037555 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555
Rps10 ENSMUSG00000052146 0.0579478375430679 0.173843512629204 0.853694531487825 1 1 1
Gan ENSMUSG00000052557 0.0969812105731562 0.290943631719469 0.399548817627028 0.5155648232968 0.5155648232968 0.5155648232968
Uba2 ENSMUSG00000052997 0.514934023620344 1 1 1 0.926333123228344 1
Pom121 ENSMUSG00000053293 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Ggcx ENSMUSG00000053460 1 1 0.781170242226513 1 0.852940894477647 1
Eif3k ENSMUSG00000053565 0.78180291566155 0.926658283600152 0.346899083932133 0.926658283600152 0.926658283600152 0.926658283600152
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Rnf181 ENSMUSG00000055850 0.926003599371282 0.926003599371282 0.058823267388015 0.176469802164045 0.577829325134931 0.866743987702397
Tgoln1 ENSMUSG00000056429 0.0007950941817707 0.0023852825453121 0.175044824745981 0.262567237118971 0.297095062262362 0.297095062262362
Foxk1 ENSMUSG00000056493 0.643359829732651 0.852832278580641 0.852832278580641 0.852832278580641 0.577829325134931 0.852832278580641
Rpl38 ENSMUSG00000057322 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Birc2 ENSMUSG00000057367 0.853801250889739 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Rpl32 ENSMUSG00000057841 0.343537039781257 0.596076093399921 0.397384062266614 0.596076093399921 0.710416009055326 0.710416009055326
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Rpl10-ps3 ENSMUSG00000058443 0.342026805366747 0.51304020805012 0.255530331334266 0.51304020805012 0.926658283600152 0.926658283600152
Rpl23a ENSMUSG00000058546 0.254414773803597 0.711240436189781 0.711240436189781 0.711240436189781 0.643359829732651 0.711240436189781
Rpl30 ENSMUSG00000058600 0.455625354715449 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620345 0.772401035430517
Rpl18 ENSMUSG00000059070 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917 0.782117202022501 0.782117202022501
Rpl11 ENSMUSG00000059291 0.346527959006435 0.520348625898199 0.7802108304765 0.7802108304765 0.346899083932133 0.520348625898199
Eif4a1 ENSMUSG00000059796 0.575536202757516 0.924987846321933 0.851061028660105 0.924987846321933 0.924987846321933 0.924987846321933
Tnip2 ENSMUSG00000059866 0.118714930081337 0.35614479024401 0.456305241393103 0.643359829732651 0.643359829732651 0.643359829732651
Rpl3 ENSMUSG00000060036 0.347639524025037 0.763717084845103 0.509144723230069 0.763717084845103 0.852832278580641 0.852832278580641
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Rpl35a ENSMUSG00000060636 0.21549027811633 0.64647083434899 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Rpl26 ENSMUSG00000060938 0.295581119060361 0.522013263352776 0.348008842235184 0.522013263352776 0.926333123228344 0.926333123228344
Rps17 ENSMUSG00000061787 0.0761127945805736 0.228338383741721 0.711240436189781 0.711240436189781 0.577829325134931 0.711240436189781
Rpl34 ENSMUSG00000062006 0.514300775319626 0.771451162979439 0.300095920620218 0.771451162979439 0.926333123228344 0.926333123228344
Rpl7a ENSMUSG00000062647 0.711034989117171 1 0.711034989117171 1 1 1
Rps15 ENSMUSG00000063457 0.0953125666339397 0.285937699901819 0.21549027811633 0.323235417174495 0.643853282854191 0.643853282854191
Chchd1 ENSMUSG00000063787 0.78180291566155 0.926333123228344 0.400265374208515 0.926333123228344 0.926333123228344 0.926333123228344
Rab44 ENSMUSG00000064147 0.853372965654504 0.853372965654504 0.504160198969763 0.853372965654504 0.776750778128093 0.853372965654504
Rplp0 ENSMUSG00000067274 0.640861491578951 0.961292237368426 0.640355507848752 0.961292237368426 1 1
Rps28 ENSMUSG00000067288 0.300095920620218 0.450143880930327 0.253294730253594 0.450143880930327 0.709375484777034 0.709375484777034
Tcp1 ENSMUSG00000068039 0.782117202022501 0.782117202022501 0.216214347033995 0.648643041101984 0.78180291566155 0.782117202022501
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Hist2h2be ENSMUSG00000068854 0.5155648232968 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620345 0.576973746230334
Dap3 ENSMUSG00000068921 1 1 0.0930846407079412 0.279253922123823 0.514934023620345 0.772401035430517
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Rpl23 ENSMUSG00000071415 0.643853282854191 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Ptrh2 ENSMUSG00000072582 0.5155648232968 0.7733472349452 0.0763619660358786 0.229085898107636 0.78148726569172 0.78148726569172
Pgap1 ENSMUSG00000073678 0.0315593554855452 0.0946780664566357 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Rpl31 ENSMUSG00000073702 0.214764523938594 0.598244634262948 1 1 0.398829756175299 0.598244634262948
Alg6 ENSMUSG00000073792 0.298224585822431 0.753185793980836 0.850036160745954 0.850036160745954 0.502123862653891 0.753185793980836
Rpl13a ENSMUSG00000074129 0.298599969973533 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Rpl36a ENSMUSG00000079435 0.447621891168214 0.67143283675232 0.347639524025037 0.67143283675232 0.710416009055326 0.710416009055326
Rpl39 ENSMUSG00000079641 0.300095920620218 0.450143880930327 0.255530331334266 0.450143880930327 0.92622377157404 0.92622377157404
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Gm20716 ENSMUSG00000093752 0.711854160331342 0.711854160331342 0.297848640636702 0.599323226440542 0.399548817627028 0.599323226440542
RPL24 ENSMUSG00000098274 0.252545530864481 0.598244634262948 0.398829756175299 0.598244634262948 0.926441990075769 0.926441990075769

DNA Replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Gmnn ENSMUSG00000006715 0.926550375688041 0.926550375688041 0.397384062266614 0.596076093399921 0.0583853430099098 0.175156029029729
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Cdc7 ENSMUSG00000029283 0.853694531487825 0.853694531487825 0.398829756175299 0.598244634262948 0.347639524025037 0.598244634262948
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Gins3 ENSMUSG00000031669 0.386972299618399 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Synthesis of DNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Gins3 ENSMUSG00000031669 0.386972299618399 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdhd ENSMUSG00000000171 0.926441990075769 0.926441990075769 0.45596561163947 0.926441990075769 0.926333123228344 0.926441990075769
Ndufa9 ENSMUSG00000000399 0.711240436189781 0.852832278580641 0.297095062262362 0.852832278580641 0.852832278580641 0.852832278580641
Srr ENSMUSG00000001323 0.514300775319626 0.771451162979439 0.348008842235184 0.771451162979439 0.926658283600152 0.926658283600152
Akr1b3 ENSMUSG00000001642 0.853372965654504 0.853801250889739 0.392985378348026 0.853801250889739 0.853801250889739 0.853801250889739
Cd320 ENSMUSG00000002308 0.78148726569172 0.78148726569172 0.711854160331342 0.78148726569172 0.167569692867574 0.502709078602721
Gmpr2 ENSMUSG00000002326 0.505169133438821 0.757753700158231 0.179945789077372 0.539837367232116 1 1
Ndufb2 ENSMUSG00000002416 0.853694531487825 0.853694531487825 0.250285839267991 0.750857517803972 0.572616808177226 0.853694531487825
Abhd3 ENSMUSG00000002475 0.578113371816017 0.853372965654504 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Pon1 ENSMUSG00000002588 0.847439075718677 1 1 1 0.0963817845133186 0.289145353539956
Gnmt ENSMUSG00000002769 0.775217051297351 0.92356607045265 0.197598874030478 0.592796622091434 0.92356607045265 0.92356607045265
Timmdc1 ENSMUSG00000002846 0.852832278580641 0.852832278580641 0.119631084167591 0.358893252502774 0.852832278580641 0.852832278580641
Cyp4f18 ENSMUSG00000003484 0.852065168704833 0.926658283600152 0.454600801949285 0.926658283600152 0.926658283600152 0.926658283600152
Prodh ENSMUSG00000003526 0.0763619660358786 0.229085898107636 0.456305241393103 0.514300775319626 0.514300775319626 0.514300775319626
As3mt ENSMUSG00000003559 1 1 0.577829325134931 1 0.782117202022501 1
Gstm5 ENSMUSG00000004032 0.0953125666339397 0.285937699901819 0.643359829732651 0.643359829732651 0.578113371816017 0.643359829732651
Etfb ENSMUSG00000004610 0.214037080764326 0.518116419532656 0.345410946355104 0.518116419532656 0.711650020253571 0.711650020253571
Sgsh ENSMUSG00000005043 0.849457568495547 0.849457568495547 0.213307944885796 0.639923834657388 0.562539849036184 0.843809773554277
Hmox1 ENSMUSG00000005413 0.00253244992826164 0.00759734978478493 0.447621891168214 0.67143283675232 0.926333123228344 0.926333123228344
Apoa2 ENSMUSG00000005681 0.0936419271039908 0.280925781311972 0.7802108304765 0.7802108304765 0.643359829732651 0.7802108304765
Inpp5k ENSMUSG00000006127 0.513026869856283 0.578113371816017 0.29252580908486 0.578113371816017 0.578113371816017 0.578113371816017
Elovl1 ENSMUSG00000006390 0.640861491578951 0.853372965654504 0.853372965654504 0.853372965654504 0.295581119060361 0.853372965654504
Mgst1 ENSMUSG00000008540 0.573498913947369 0.964296486337094 0.642864324224729 0.964296486337094 1 1
Fpgs ENSMUSG00000009566 0.024062085667391 0.0721862570021729 0.300095920620218 0.450143880930327 0.711854160331342 0.711854160331342
Sdhb ENSMUSG00000009863 1 1 0.643359829732651 1 0.853049270252403 1
Kdsr ENSMUSG00000009905 0.643359829732651 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Taz ENSMUSG00000009995 0.455625354715449 0.780851835278817 0.780851835278817 0.780851835278817 0.711034989117171 0.780851835278817
Acaa1b ENSMUSG00000010651 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.573205482926791 0.711034989117171
Mogat1 ENSMUSG00000012187 0.0430444900328089 0.129133470098427 0.926441990075769 0.926441990075769 0.925331064166297 0.926441990075769
Ndufa2 ENSMUSG00000014294 0.513026869856283 0.769540304784424 0.17924968721805 0.537749061654149 0.926003599371282 0.926003599371282
Dguok ENSMUSG00000014554 0.505169133438821 0.757753700158231 0.853801250889739 0.853801250889739 0.398829756175299 0.757753700158231
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ndufa1 ENSMUSG00000016427 0.346899083932133 0.711650020253571 0.514934023620345 0.711650020253571 0.711650020253571 0.711650020253571
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Smpd2 ENSMUSG00000019822 0.0763619660358787 0.229085898107636 0.514934023620345 0.772401035430517 1 1
Phykpl ENSMUSG00000020359 0.853801250889739 0.853801250889739 0.147458757705094 0.442376273115283 0.576973746230334 0.853801250889739
Aspa ENSMUSG00000020774 0.146141353215795 0.438424059647386 0.298599969973533 0.4478999549603 0.926658283600152 0.926658283600152
Nme2 ENSMUSG00000020857 0.213307944885796 0.639923834657388 0.706616781330066 0.706616781330066 0.453225835454266 0.679838753181399
Adprm ENSMUSG00000020910 0.711650020253571 0.711650020253571 0.347639524025037 0.711650020253571 0.711240436189781 0.711650020253571
Gstz1 ENSMUSG00000021033 0.455625354715448 0.851061028660105 0.851061028660105 0.851061028660105 0.7802108304765 0.851061028660105
Ippk ENSMUSG00000021385 0.575536202757516 0.863304304136274 0.45596561163947 0.863304304136274 1 1
Slc35b3 ENSMUSG00000021432 0.642366752097095 0.642366752097095 0.445116333668945 0.642366752097095 0.0644521829047255 0.193356548714177
Fbp2 ENSMUSG00000021456 0.92622377157404 0.92622377157404 0.639337105615665 0.92622377157404 0.639337105615665 0.92622377157404
Sptlc1 ENSMUSG00000021468 0.852832278580641 0.852832278580641 0.147458757705095 0.442376273115284 0.780851835278818 0.852832278580641
Ndufs6 ENSMUSG00000021606 0.299349060054895 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Nudt13 ENSMUSG00000021809 0.454942951775341 0.682414427663012 0.853801250889739 0.853801250889739 0.0763619660358786 0.229085898107636
Hrsp12 ENSMUSG00000022323 0.643359829732651 0.643359829732651 0.578396848531894 0.643359829732651 0.299349060054895 0.643359829732651
Ndufb9 ENSMUSG00000022354 0.118714930081337 0.35614479024401 0.345410946355104 0.518116419532656 0.709375484777034 0.709375484777034
Ndufa6 ENSMUSG00000022450 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Dgat1 ENSMUSG00000022555 0.513665062682276 0.772401035430517 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501
Pycrl ENSMUSG00000022571 0.926441990075769 0.926441990075769 0.29252580908486 0.438788713627291 0.29252580908486 0.438788713627291
St3gal6 ENSMUSG00000022747 0.456305241393104 0.684457862089656 0.252920381501207 0.684457862089656 0.707899741868332 0.707899741868332
Umps ENSMUSG00000022814 0.853480389728993 0.853480389728993 0.0761127945805736 0.114542949053818 0.0763619660358785 0.114542949053818
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Cbr3 ENSMUSG00000022947 0.171503747555202 0.514511242665607 0.514934023620345 0.570836132666921 0.570836132666921 0.570836132666921
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Ndufa5 ENSMUSG00000023089 0.576973746230334 0.643853282854191 0.397384062266614 0.643853282854191 0.643853282854191 0.643853282854191
Synj2 ENSMUSG00000023805 0.853372965654504 0.853372965654504 0.78180291566155 0.853372965654504 0.514934023620345 0.853372965654504
Slc25a27 ENSMUSG00000023912 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342 0.347639524025037 0.711854160331342
Ndufaf7 ENSMUSG00000024082 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026 1 1
Ndufv2 ENSMUSG00000024099 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.456305241393103 0.642366752097095
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Psat1 ENSMUSG00000024640 0.120850531362929 0.362551594088788 0.456305241393103 0.5155648232968 0.5155648232968 0.5155648232968
Gna14 ENSMUSG00000024697 0.576973746230334 0.781645261743309 0.0967032506702098 0.290109752010629 0.781645261743309 0.781645261743309
Tm7sf2 ENSMUSG00000024799 0.120850531362929 0.362551594088788 0.454942951775342 0.682414427663012 0.708745765211584 0.708745765211584
Pcyt2 ENSMUSG00000025137 0.255530331334266 0.383295497001398 0.255530331334266 0.383295497001398 0.780851835278818 0.780851835278818
Sat1 ENSMUSG00000025283 0.7802108304765 0.7802108304765 0.513665062682276 0.770497594023414 0.511097249598474 0.770497594023414
Ormdl2 ENSMUSG00000025353 0.78180291566155 0.78180291566155 0.455625354715449 0.683438032073173 0.147458757705094 0.442376273115283
Echs1 ENSMUSG00000025465 0.216214347033995 0.648643041101984 0.926441990075769 0.926441990075769 0.573498913947369 0.860248370921054
Gusb ENSMUSG00000025534 0.455965611639469 0.455965611639469 0.298599969973533 0.450143880930327 0.300095920620218 0.450143880930327
Phkg1 ENSMUSG00000025537 0.0328221470541517 0.098466441162455 0.926550375688041 0.926550375688041 0.926441990075769 0.926550375688041
Tyms ENSMUSG00000025747 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.254787123615605 0.764361370846816
Nudt5 ENSMUSG00000025817 0.45596561163947 0.577829325134931 0.399548817627028 0.577829325134931 0.577829325134931 0.577829325134931
Iscu ENSMUSG00000025825 0.058823267388015 0.0882349010820225 0.0426702157436794 0.0882349010820225 0.25141795904251 0.25141795904251
Aasdhppt ENSMUSG00000025894 0.455625354715449 0.683438032073173 0.299349060054895 0.683438032073173 0.782117202022501 0.782117202022501
Ndufb3 ENSMUSG00000026032 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739
Ormdl1 ENSMUSG00000026097 0.578396848531894 1 1 1 0.712057867818062 1
Dtymk ENSMUSG00000026281 0.926550375688041 0.926550375688041 0.710208797518812 0.926550375688041 0.299349060054895 0.898047180164686
Dbi ENSMUSG00000026385 0.254787123615605 0.764361370846816 0.640861491578951 0.7802108304765 0.7802108304765 0.7802108304765
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Fh1 ENSMUSG00000026526 0.853372965654504 0.853372965654504 0.643359829732651 0.853372965654504 0.641867098978198 0.853372965654504
Uck2 ENSMUSG00000026558 0.256271555563966 0.768814666691898 0.642366752097095 0.852832278580641 0.852832278580641 0.852832278580641
Hsd17b7 ENSMUSG00000026675 0.0763619660358786 0.229085898107636 0.577829325134931 0.866743987702397 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Lpcat4 ENSMUSG00000027134 0.300095920620218 0.852504981253341 0.852504981253341 0.852504981253341 0.578113371816017 0.852504981253341
Dut ENSMUSG00000027203 0.578113371816017 0.712057867818062 0.712057867818062 0.712057867818062 0.711854160331342 0.712057867818062
Ivd ENSMUSG00000027332 0.780851835278818 0.853801250889739 0.853801250889739 0.853801250889739 0.252545530864481 0.757636592593443
Idh3b ENSMUSG00000027406 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.399548817627028 0.781170242226513
Fabp5 ENSMUSG00000027533 0.0953125666339397 0.285937699901819 0.255901190956604 0.383851786434905 1 1
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Ggt7 ENSMUSG00000027603 0.781170242226513 0.926333123228344 0.148115998140416 0.444347994421247 0.926333123228344 0.926333123228344
Nfs1 ENSMUSG00000027618 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152 0.711854160331342 0.926658283600152
Gnb4 ENSMUSG00000027669 0.300095920620218 0.852504981253341 0.852504981253341 0.852504981253341 0.778911768167544 0.852504981253341
Ndufb5 ENSMUSG00000027673 0.640861491578951 0.711854160331342 0.45596561163947 0.711854160331342 0.711854160331342 0.711854160331342
Acad9 ENSMUSG00000027710 0.711034989117171 0.782117202022501 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501
Ndst3 ENSMUSG00000027977 0.5155648232968 1 0.853907737111068 1 1 1
Pip5k1a ENSMUSG00000028126 0.782117202022501 0.782117202022501 0.398829756175299 0.681901202923927 0.454600801949285 0.681901202923927
Adh5 ENSMUSG00000028138 0.178901132102685 0.268874530827074 0.17924968721805 0.268874530827074 0.852504981253341 0.852504981253341
Them4 ENSMUSG00000028145 0.577829325134931 0.711650020253571 0.5155648232968 0.711650020253571 0.711650020253571 0.711650020253571
Cth ENSMUSG00000028179 0.144820068500793 0.268351698154027 0.178901132102685 0.268351698154027 0.924872384323464 0.924872384323464
Decr1 ENSMUSG00000028223 0.297848640636702 0.893545921910107 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Coq3 ENSMUSG00000028247 0.643359829732651 0.643359829732651 0.45596561163947 0.643359829732651 0.400265374208515 0.643359829732651
Slc44a5 ENSMUSG00000028360 0.120545895661628 0.361637686984883 0.508488713161374 0.762733069742061 0.853694531487825 0.853694531487825
Ppcs ENSMUSG00000028636 0.926441990075769 0.926441990075769 0.514934023620345 0.772401035430517 0.146141353215796 0.438424059647387
Ppt1 ENSMUSG00000028657 0.0240620856673909 0.0721862570021727 0.853907737111068 0.853907737111068 0.782117202022501 0.853907737111068
Urod ENSMUSG00000028684 0.926658283600152 0.926658283600152 0.397384062266614 0.926658283600152 0.926550375688041 0.926658283600152
Cda ENSMUSG00000028755 0.577259514257969 0.577259514257969 0.119631084167592 0.358893252502775 0.399548817627028 0.577259514257969
Mecr ENSMUSG00000028910 0.215852522998048 0.637013771824329 0.513346277289108 0.637013771824329 0.637013771824329 0.637013771824329
Pank4 ENSMUSG00000029056 0.711034989117171 0.711034989117171 0.709375484777034 0.711034989117171 0.511742979522636 0.711034989117171
Man2b2 ENSMUSG00000029119 0.853372965654504 0.926003599371282 0.577259514257969 0.926003599371282 0.926003599371282 0.926003599371282
Paics ENSMUSG00000029247 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.511097249598474 0.511097249598474
Agpat9 ENSMUSG00000029314 0.5155648232968 0.711034989117171 0.0964252305385472 0.289275691615642 0.711034989117171 0.711034989117171
Psph ENSMUSG00000029446 0.00660511570760555 0.0198153471228166 0.572616808177226 0.572616808177226 0.454600801949285 0.572616808177226
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Wasl ENSMUSG00000029684 0.0158546704257247 0.047564011277174 0.643853282854191 0.853907737111068 0.853907737111068 0.853907737111068
Gstk1 ENSMUSG00000029864 0.0331400397096515 0.0994201191289544 0.852832278580641 0.852832278580641 0.578113371816017 0.852832278580641
Etnk1 ENSMUSG00000030275 0.781170242226513 0.852832278580641 0.0426702157436794 0.128010647231038 0.852832278580641 0.852832278580641
Sec13 ENSMUSG00000030298 0.782117202022501 0.853372965654504 0.643853282854191 0.853372965654504 0.853372965654504 0.853372965654504
Slc27a5 ENSMUSG00000030382 0.0726276229843141 0.181275797044394 0.92622377157404 0.92622377157404 0.120850531362929 0.181275797044394
Cyp2r1 ENSMUSG00000030670 0.13849172243875 0.415475167316251 0.851061028660105 0.924930181917758 0.924930181917758 0.924930181917758
Lyve1 ENSMUSG00000030787 0.346899083932133 0.520348625898199 0.180293335960318 0.520348625898199 0.78180291566155 0.78180291566155
Acadsb ENSMUSG00000030861 0.0592616003460511 0.177784801038153 0.25141795904251 0.377126938563765 0.926333123228344 0.926333123228344
Crym ENSMUSG00000030905 0.643853282854191 0.965779924281287 0.058823267388015 0.176469802164045 1 1
Oat ENSMUSG00000030934 0.509798138101151 0.703556284613037 0.633039971999413 0.703556284613037 0.703556284613037 0.703556284613037
Ndufb11 ENSMUSG00000031059 0.643359829732651 0.643359829732651 0.577259514257969 0.643359829732651 0.398829756175299 0.643359829732651
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Phka2 ENSMUSG00000031295 0.782117202022501 0.782117202022501 0.00270924971713393 0.00812774915140177 0.214764523938594 0.322146785907891
Mtm1 ENSMUSG00000031337 0.853694531487825 0.853694531487825 0.853587578053106 0.853694531487825 0.254041925545275 0.762125776635825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Agpat5 ENSMUSG00000031467 0.346527959006435 0.926003599371282 0.641867098978198 0.926003599371282 0.926003599371282 0.926003599371282
Pgls ENSMUSG00000031807 0.0847074989275803 0.12706124839137 0.443306001726868 0.443306001726868 0.0241933715424143 0.0725801146272428
Hsd17b2 ENSMUSG00000031844 0.446552171959625 0.702664132234038 0.622066039218108 0.702664132234038 0.702664132234038 0.702664132234038
Arv1 ENSMUSG00000031982 0.29252580908486 0.399548817627028 0.21549027811633 0.399548817627028 0.399548817627028 0.399548817627028
Pts ENSMUSG00000032067 0.782117202022501 0.782117202022501 0.299349060054895 0.521459286037555 0.347639524025037 0.521459286037555
Apoa1 ENSMUSG00000032083 0.50075242599667 0.751128638995005 1 1 0.291370537767947 0.751128638995005
Carm1 ENSMUSG00000032185 0.640861491578951 0.640861491578951 0.0936419271039908 0.280925781311972 0.398829756175299 0.598244634262948
Bckdhb ENSMUSG00000032263 0.852832278580641 0.926278508226733 0.926278508226733 0.926278508226733 0.852832278580641 0.926278508226733
Man2c1 ENSMUSG00000032295 0.348008842235184 0.455625354715449 0.455625354715449 0.455625354715449 0.297095062262362 0.455625354715449
Etfa ENSMUSG00000032314 0.346156228791382 0.850036160745954 0.780049698709835 0.850036160745954 0.850036160745954 0.850036160745954
Gng11 ENSMUSG00000032766 0.0766111619812296 0.229833485943689 0.711034989117171 1 1 1
Mcee ENSMUSG00000033429 0.926441990075769 0.926441990075769 0.0592616003460512 0.177784801038154 0.711240436189781 0.926441990075769
Ptplad1 ENSMUSG00000033629 0.853372965654504 0.926550375688041 0.0721303428592824 0.216391028577847 0.926550375688041 0.926550375688041
Phka1 ENSMUSG00000034055 0.711650020253571 0.926333123228344 0.452880492349546 0.926333123228344 0.926333123228344 0.926333123228344
Tpst1 ENSMUSG00000034118 0.148772260628989 0.223158390943484 0.148115998140416 0.223158390943484 0.853907737111068 0.853907737111068
Parp14 ENSMUSG00000034422 0.0168921052924601 0.0506763158773803 0.144820068500793 0.21723010275119 0.641867098978198 0.641867098978198
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Nudt19 ENSMUSG00000034875 0.782117202022501 0.926550375688041 0.926550375688041 0.926550375688041 0.853049270252403 0.926550375688041
Nubpl ENSMUSG00000035142 0.710208797518812 0.710208797518812 0.511742979522636 0.710208797518812 0.710001140920767 0.710208797518812
Nup37 ENSMUSG00000035351 0.853801250889739 0.853801250889739 0.511742979522636 0.853801250889739 0.853372965654504 0.853801250889739
Ndufa3 ENSMUSG00000035674 0.711034989117171 0.92622377157404 0.398829756175299 0.92622377157404 0.92622377157404 0.92622377157404
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Ndufa13 ENSMUSG00000036199 0.507830090867449 0.761745136301173 0.455625354715449 0.761745136301173 0.780851835278818 0.780851835278818
Nudt1 ENSMUSG00000036639 0.216214347033995 0.382180685423408 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Phkb ENSMUSG00000036879 1 1 0.243396309647536 0.521459286037555 0.347639524025037 0.521459286037555
Hk1 ENSMUSG00000037012 0.642864324224729 0.852940894477647 0.852940894477647 0.852940894477647 0.400265374208515 0.852940894477647
Slc35b2 ENSMUSG00000037089 0.255901190956604 0.59607609339992 0.397384062266613 0.59607609339992 0.926550375688041 0.926550375688041
Ndufc1 ENSMUSG00000037152 0.576973746230334 0.853694531487825 0.252920381501207 0.75876114450362 0.853694531487825 0.853694531487825
Pank2 ENSMUSG00000037514 0.710001140920767 0.710001140920767 0.576973746230334 0.710001140920767 0.578113371816017 0.710001140920767
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Nup205 ENSMUSG00000038759 0.214037080764326 0.642111242292977 0.712057867818062 0.853694531487825 0.853694531487825 0.853694531487825
Adk ENSMUSG00000039197 0.78148726569172 0.853801250889739 0.853801250889739 0.853801250889739 0.643359829732651 0.853801250889739
Ccbl1 ENSMUSG00000039648 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152 0.853907737111068 0.926658283600152
Ndufb10 ENSMUSG00000040048 0.577829325134931 0.853480389728993 0.853480389728993 0.853480389728993 0.456305241393103 0.853480389728993
Ppapdc2 ENSMUSG00000040105 0.300095920620218 0.853694531487825 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825
Blvrb ENSMUSG00000040466 0.399548817627028 0.599323226440542 0.341647690705446 0.599323226440542 0.924286968561133 0.924286968561133
Dnph1 ENSMUSG00000040658 0.0579478375430677 0.173843512629203 0.782117202022501 1 1 1
Prkd2 ENSMUSG00000041187 0.0947558980989551 0.284267694296865 0.926658283600152 1 1 1
Hibch ENSMUSG00000041426 0.453225835454266 0.679838753181399 0.146141353215796 0.438424059647387 0.776919261684345 0.776919261684345
Prelp ENSMUSG00000041577 0.395928178642446 0.593892267963669 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054
Ndufa7 ENSMUSG00000041881 0.853801250889739 1 0.25141795904251 0.754253877127531 1 1
Agrn ENSMUSG00000041936 0.0969812105731562 0.290943631719469 0.711650020253571 0.78180291566155 0.78180291566155 0.78180291566155
Csgalnact2 ENSMUSG00000042042 0.782117202022501 0.853694531487825 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825
Bhmt2 ENSMUSG00000042118 0.255530331334266 0.766590994002797 0.712057867818062 1 1 1
Dhrs7b ENSMUSG00000042569 0.78180291566155 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Hilpda ENSMUSG00000043421 0.0741204440774082 0.222361332232225 0.397384062266614 0.397384062266614 0.344663224299303 0.397384062266614
Sptssa ENSMUSG00000044408 0.348008842235184 1 0.852832278580641 1 1 1
Uqcrq ENSMUSG00000044894 0.255901190956604 0.383851786434905 0.254414773803597 0.383851786434905 0.708745765211584 0.708745765211584
Hs6st1 ENSMUSG00000045216 0.454600801949285 0.850380130396972 0.850380130396972 0.850380130396972 0.706831781264721 0.850380130396972
Fahd1 ENSMUSG00000045316 0.926003599371281 0.926003599371281 0.708534948098331 0.926003599371281 0.640861491578951 0.926003599371281
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Arsj ENSMUSG00000046561 0.0076814493263989 0.0230443479791967 0.116265430850263 0.174398146275395 0.711034989117171 0.711034989117171
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Slc25a2 ENSMUSG00000050304 0.342026805366746 0.51304020805012 0.641616487517698 0.641616487517698 0.212942741031873 0.51304020805012
Ptges ENSMUSG00000050737 0.78180291566155 0.78180291566155 0.148115998140416 0.444347994421247 0.399548817627028 0.599323226440542
B3galt6 ENSMUSG00000050796 0.853694531487825 0.853907737111068 0.0168921052924602 0.0506763158773805 0.853907737111068 0.853907737111068
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Plcb1 ENSMUSG00000051177 0.17750354896016 0.26625532344024 0.0914116769446391 0.26625532344024 0.852065168704833 0.852065168704833
Suclg1 ENSMUSG00000052738 0.643359829732651 0.643359829732651 0.511742979522636 0.643359829732651 0.642864324224729 0.643359829732651
Pom121 ENSMUSG00000053293 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Rpia ENSMUSG00000053604 0.926604389137101 0.926604389137101 0.515249728559995 0.772874592839992 0.514617706526787 0.772874592839992
Mat2a ENSMUSG00000053907 0.256271555563967 0.577259514257969 0.400265374208515 0.577259514257969 0.577259514257969 0.577259514257969
Lclat1 ENSMUSG00000054469 0.400265374208515 0.576973746230334 0.45596561163947 0.576973746230334 0.576973746230334 0.576973746230334
Aadat ENSMUSG00000057228 0.926333123228344 0.926333123228344 0.0969812105731562 0.290943631719469 0.853694531487825 0.926333123228344
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Hadhb ENSMUSG00000059447 0.514934023620345 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Uqcr10 ENSMUSG00000059534 0.454942951775342 0.682414427663012 0.254787123615605 0.682414427663012 0.851061028660105 0.851061028660105
Ndufs8 ENSMUSG00000059734 0.851732715229127 0.851732715229127 0.514934023620345 0.851732715229127 0.851732715229127 0.851732715229127
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Pla2g16 ENSMUSG00000060675 0.299349060054895 0.643853282854191 0.577829325134931 0.643853282854191 0.643853282854191 0.643853282854191
Akr1b10 ENSMUSG00000061758 0.511742979522636 0.7733472349452 0.5155648232968 0.7733472349452 0.853049270252403 0.853049270252403
Cyp26b1 ENSMUSG00000063415 0.252545530864481 0.392243127063687 0.392243127063687 0.392243127063687 0.346899083932133 0.392243127063687
Nmral1 ENSMUSG00000063445 0.513026869856283 0.851954599472143 0.851954599472143 0.851954599472143 0.577829325134931 0.851954599472143
Hsd3b2 ENSMUSG00000063730 0.455625354715449 0.683438032073173 0.926658283600152 0.926658283600152 0.146141353215796 0.438424059647387
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Uqcrh ENSMUSG00000063882 0.514934023620345 0.642864324224729 0.642864324224729 0.642864324224729 0.577259514257969 0.642864324224729
mt-Nd3 ENSMUSG00000064360 0.214037080764326 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Rdh11 ENSMUSG00000066441 0.926333123228344 0.926333123228344 0.925331064166297 0.926333123228344 0.567513221841557 0.926333123228344
Mthfs ENSMUSG00000066442 0.578113371816017 0.711034989117171 0.146141353215796 0.438424059647387 0.711034989117171 0.711034989117171
Mfsd7b ENSMUSG00000066595 0.17924968721805 0.537749061654149 0.781170242226513 1 1 1
Marcks ENSMUSG00000069662 1 1 0.711034989117171 1 0.78148726569172 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Ces3a ENSMUSG00000069922 0.252920381501207 0.395562602091096 0.395562602091096 0.395562602091096 0.34578389175364 0.395562602091096
Ugt2b36 ENSMUSG00000070704 0.54332839150188 0.691038632946509 0.691038632946509 0.691038632946509 0.617271014427057 0.691038632946509
Cpne1 ENSMUSG00000074643 0.925217182211634 0.925217182211634 0.77858338846904 0.925217182211634 0.575824878403157 0.925217182211634
Itpa ENSMUSG00000074797 0.924639851733043 0.925217182211634 0.0969812105731562 0.290943631719469 0.925217182211634 0.925217182211634
B3galt5 ENSMUSG00000074892 0.782117202022501 0.782117202022501 0.643359829732651 0.782117202022501 0.711240436189781 0.782117202022501
Amd1 ENSMUSG00000075232 0.711854160331342 0.711854160331342 0.255530331334266 0.711854160331342 0.711034989117171 0.711854160331342
Gpx4 ENSMUSG00000075706 0.171859370212435 0.515578110637306 0.400265374208515 0.600398061312773 0.852504981253341 0.852504981253341
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Cers1 ENSMUSG00000087408 0.514934023620345 0.772401035430517 0.455625354715449 0.772401035430517 0.926333123228344 0.926333123228344
Uckl1 ENSMUSG00000089917 0.255901190956604 0.383851786434906 0.214037080764326 0.383851786434906 0.78180291566155 0.78180291566155
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Switching of origins to a post-replicative state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Dual incision in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Orc1 removal from chromatin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

S Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Esco1 ENSMUSG00000024293 0.576973746230333 0.853801250889739 0.853801250889739 0.853801250889739 0.297095062262362 0.853801250889739
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Gins3 ENSMUSG00000031669 0.386972299618399 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Transcriptional Regulation by TP53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp385a ENSMUSG00000000552 0.92416823462528 0.92416823462528 0.398108175780842 0.763717084845103 0.509144723230069 0.763717084845103
Prdx2 ENSMUSG00000005161 0.712057867818062 1 0.45596561163947 1 1 1
Ttc5 ENSMUSG00000006288 0.710001140920767 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Supt4a ENSMUSG00000020485 0.295581119060361 0.443371678590541 0.120850531362929 0.362551594088788 0.508488713161374 0.508488713161374
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Slmo1 ENSMUSG00000024530 0.11993617140438 0.359808514213139 0.780851835278818 0.78148726569172 0.78148726569172 0.78148726569172
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Ssrp1 ENSMUSG00000027067 0.78180291566155 0.78180291566155 0.0116356061791785 0.0349068185375355 0.575536202757516 0.78180291566155
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Lamtor2 ENSMUSG00000028062 0.453570536021945 0.454600801949285 0.0766111619812296 0.229833485943689 0.454600801949285 0.454600801949285
Prdx1 ENSMUSG00000028691 0.926658283600152 0.926658283600152 0.78148726569172 0.926658283600152 0.710208797518812 0.926658283600152
Taf12 ENSMUSG00000028899 0.0238002551499929 0.0714007654499788 0.576973746230334 0.576973746230334 0.453225835454266 0.576973746230334
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Casp2 ENSMUSG00000029863 0.926333123228344 0.926333123228344 0.348008842235184 0.867170057724026 0.578113371816017 0.867170057724026
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ehmt1 ENSMUSG00000036893 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.514934023620344 0.853801250889739
Sesn1 ENSMUSG00000038332 0.347639524025037 0.853587578053106 0.852395395941406 0.853587578053106 0.853587578053106 0.853587578053106
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Cnot4 ENSMUSG00000038784 0.0579478375430677 0.173843512629203 0.782117202022501 0.782117202022501 0.398829756175299 0.598244634262948
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Lamtor4 ENSMUSG00000050552 0.177153312234059 0.531459936702178 0.393724994268831 0.590587491403246 0.708323672944427 0.708323672944427
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Cnot10 ENSMUSG00000056167 0.400265374208515 0.667674500503417 0.445116333668945 0.667674500503417 0.850151080737202 0.850151080737202
Rbbp4 ENSMUSG00000057236 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.710001140920767 0.926333123228344
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Tmem219 ENSMUSG00000060538 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.926003599371281 0.92622377157404
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Lamtor5 ENSMUSG00000087260 0.514934023620345 0.772401035430517 0.34837756124189 0.772401035430517 0.926658283600152 0.926658283600152
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

Degradation of GLI1 by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Numb ENSMUSG00000021224 0.577259514257969 0.640355507848752 0.142830916318171 0.428492748954512 0.640355507848752 0.640355507848752
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Gap-filling DNA repair synthesis and ligation in TC-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Dual Incision in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Regulation of RUNX2 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Transcriptional regulation by RUNX2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sox9 ENSMUSG00000000567 0.254414773803597 0.707899741868332 0.511097249598474 0.707899741868332 0.707899741868332 0.707899741868332
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

TP53 Regulates Metabolic Genes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prdx2 ENSMUSG00000005161 0.712057867818062 1 0.45596561163947 1 1 1
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Lamtor2 ENSMUSG00000028062 0.453570536021945 0.454600801949285 0.0766111619812296 0.229833485943689 0.454600801949285 0.454600801949285
Prdx1 ENSMUSG00000028691 0.926658283600152 0.926658283600152 0.78148726569172 0.926658283600152 0.710208797518812 0.926658283600152
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Sesn1 ENSMUSG00000038332 0.347639524025037 0.853587578053106 0.852395395941406 0.853587578053106 0.853587578053106 0.853587578053106
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Lamtor4 ENSMUSG00000050552 0.177153312234059 0.531459936702178 0.393724994268831 0.590587491403246 0.708323672944427 0.708323672944427
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544
Lamtor5 ENSMUSG00000087260 0.514934023620345 0.772401035430517 0.34837756124189 0.772401035430517 0.926658283600152 0.926658283600152
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1

CDT1 association with the CDC6:ORC:origin complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gmnn ENSMUSG00000006715 0.926550375688041 0.926550375688041 0.397384062266614 0.596076093399921 0.0583853430099098 0.175156029029729
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Cul2 ENSMUSG00000024231 0.711650020253571 0.711650020253571 0.177853449259986 0.533560347779958 0.643853282854191 0.711650020253571
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Wtip ENSMUSG00000036459 0.926441990075769 0.926441990075769 0.578396848531894 0.926441990075769 0.711854160331342 0.926441990075769
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Regulation of RAS by GAPs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Dab2ip ENSMUSG00000026883 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.577829325134931 0.853907737111068
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Spred2 ENSMUSG00000045671 0.300095920620218 0.781170242226513 0.781170242226513 0.781170242226513 0.573791743469336 0.781170242226513
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Syngap1 ENSMUSG00000067629 0.300095920620218 0.450143880930327 0.211844580334808 0.450143880930327 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Rasal2 ENSMUSG00000070565 0.0763619660358786 0.144637845807821 0.096425230538547 0.144637845807821 0.926441990075769 0.926441990075769
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Assembly of the pre-replicative complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Gmnn ENSMUSG00000006715 0.926550375688041 0.926550375688041 0.397384062266614 0.596076093399921 0.0583853430099098 0.175156029029729
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

APC/C:Cdc20 mediated degradation of Securin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

APC/C:Cdc20 mediated degradation of Cyclin B

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp385a ENSMUSG00000000552 0.92416823462528 0.92416823462528 0.398108175780842 0.763717084845103 0.509144723230069 0.763717084845103
Sox9 ENSMUSG00000000567 0.254414773803597 0.707899741868332 0.511097249598474 0.707899741868332 0.707899741868332 0.707899741868332
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Med6 ENSMUSG00000002679 0.853372965654504 1 1 1 0.575824878403157 1
Prdx2 ENSMUSG00000005161 0.712057867818062 1 0.45596561163947 1 1 1
Ddx39 ENSMUSG00000005481 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.578113371816017 0.853801250889739
Ttc5 ENSMUSG00000006288 0.710001140920767 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Med8 ENSMUSG00000006392 0.5155648232968 0.643853282854191 0.514300775319626 0.643853282854191 0.643853282854191 0.643853282854191
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ints2 ENSMUSG00000018068 0.578113371816017 0.781170242226513 0.148115998140415 0.444347994421246 0.781170242226513 0.781170242226513
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Supt4a ENSMUSG00000020485 0.295581119060361 0.443371678590541 0.120850531362929 0.362551594088788 0.508488713161374 0.508488713161374
Med31 ENSMUSG00000020801 0.147458757705094 0.442376273115283 0.711240436189781 0.926658283600152 0.926658283600152 0.926658283600152
Nr1d1 ENSMUSG00000020889 0.643853282854191 0.965779924281287 0.255901190956604 0.767703572869811 1 1
Esr2 ENSMUSG00000021055 0.21549027811633 0.64647083434899 0.450094379653806 0.675141569480709 0.85326530496423 0.85326530496423
Ppm1a ENSMUSG00000021096 0.120850531362929 0.362551594088788 0.643359829732651 0.711240436189781 0.711240436189781 0.711240436189781
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Myc ENSMUSG00000022346 0.34837756124189 0.769540304784424 0.513026869856283 0.769540304784424 0.853801250889739 0.853801250889739
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Ring1 ENSMUSG00000024325 0.342026805366747 0.51304020805012 0.776243028387552 0.776243028387552 0.118714930081337 0.35614479024401
Slmo1 ENSMUSG00000024530 0.11993617140438 0.359808514213139 0.780851835278818 0.78148726569172 0.78148726569172 0.78148726569172
Nedd4l ENSMUSG00000024589 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155 0.21549027811633 0.64647083434899
Pcgf6 ENSMUSG00000025050 0.852504981253341 0.852504981253341 0.641867098978198 0.852504981253341 0.514934023620345 0.852504981253341
Ints4 ENSMUSG00000025133 0.173632433887832 0.520897301663497 0.78180291566155 0.78180291566155 0.573791743469336 0.78180291566155
Cbx8 ENSMUSG00000025578 0.0331400397096515 0.0497100595644772 0.00247508107184991 0.00742524321554974 0.782117202022501 0.782117202022501
Zfp202 ENSMUSG00000025602 0.643359829732651 0.852832278580641 0.514934023620345 0.852832278580641 0.852832278580641 0.852832278580641
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Ssrp1 ENSMUSG00000027067 0.78180291566155 0.78180291566155 0.0116356061791785 0.0349068185375355 0.575536202757516 0.78180291566155
Clp1 ENSMUSG00000027079 0.577259514257969 0.865889271386954 0.577259514257969 0.865889271386954 0.92622377157404 0.92622377157404
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Lef1 ENSMUSG00000027985 0.711034989117171 0.711034989117171 0.347639524025037 0.683438032073173 0.455625354715448 0.683438032073173
Lamtor2 ENSMUSG00000028062 0.453570536021945 0.454600801949285 0.0766111619812296 0.229833485943689 0.454600801949285 0.454600801949285
Magoh ENSMUSG00000028609 0.92622377157404 0.92622377157404 0.710208797518812 0.92622377157404 0.710208797518812 0.92622377157404
Prdx1 ENSMUSG00000028691 0.926658283600152 0.926658283600152 0.78148726569172 0.926658283600152 0.710208797518812 0.926658283600152
Taf12 ENSMUSG00000028899 0.0238002551499929 0.0714007654499788 0.576973746230334 0.576973746230334 0.453225835454266 0.576973746230334
Cpsf3l ENSMUSG00000029034 0.395928178642446 0.593892267963669 0.0763619660358787 0.229085898107636 0.926333123228344 0.926333123228344
Srsf9 ENSMUSG00000029538 0.214764523938594 0.644293571815781 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Zkscan14 ENSMUSG00000029627 0.398108175780842 0.575536202757516 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Auts2 ENSMUSG00000029673 0.452880492349546 0.679320738524319 0.146141353215796 0.438424059647387 0.92589277149125 0.92589277149125
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Casp2 ENSMUSG00000029863 0.926333123228344 0.926333123228344 0.348008842235184 0.867170057724026 0.578113371816017 0.867170057724026
Zfp248 ENSMUSG00000030145 0.214764523938594 0.21549027811633 0.0321889748775514 0.0965669246326542 0.21549027811633 0.21549027811633
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Zfp626 ENSMUSG00000030604 0.511742979522636 0.710001140920767 0.710001140920767 0.710001140920767 0.211844580334808 0.635533741004424
Hdac6 ENSMUSG00000031161 0.573498913947369 0.578113371816017 0.344663224299303 0.578113371816017 0.578113371816017 0.578113371816017
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Gtf2a2 ENSMUSG00000033543 0.514934023620345 0.643359829732651 0.643359829732651 0.643359829732651 0.178901132102685 0.536703396308054
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Snapc4 ENSMUSG00000036281 0.180293335960318 0.540880007880955 0.711650020253571 0.711650020253571 0.45596561163947 0.683948417459205
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ehmt1 ENSMUSG00000036893 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.514934023620344 0.853801250889739
H2afz ENSMUSG00000037894 0.852832278580641 1 0.454942951775342 1 1 1
Sesn1 ENSMUSG00000038332 0.347639524025037 0.853587578053106 0.852395395941406 0.853587578053106 0.853587578053106 0.853587578053106
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Cnot4 ENSMUSG00000038784 0.0579478375430677 0.173843512629203 0.782117202022501 0.782117202022501 0.398829756175299 0.598244634262948
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Rprd1a ENSMUSG00000040446 0.399548817627028 0.599323226440542 0.148115998140416 0.444347994421247 0.712057867818062 0.712057867818062
Krba1 ENSMUSG00000042810 0.216214347033995 0.648643041101985 0.926658283600152 0.926658283600152 0.853907737111068 0.926658283600152
Zfp784 ENSMUSG00000043290 0.0969812105731562 0.290943631719469 0.926658283600152 1 1 1
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Hist1h2be ENSMUSG00000047246 0.711854160331342 0.711854160331342 0.148772260628989 0.446316781886968 0.711854160331342 0.711854160331342
Tgif1 ENSMUSG00000047407 0.255901190956604 0.383851786434905 0.00768144932639892 0.0230443479791968 0.782117202022501 0.782117202022501
Lamtor4 ENSMUSG00000050552 0.177153312234059 0.531459936702178 0.393724994268831 0.590587491403246 0.708323672944427 0.708323672944427
Zfp169 ENSMUSG00000050954 0.0743693776059065 0.223108132817719 0.852832278580641 0.852832278580641 0.453570536021945 0.680355804032917
Zfp11 ENSMUSG00000051034 0.0958690133561599 0.220200812784373 0.643359829732651 0.643359829732651 0.146800541856249 0.220200812784373
Thoc7 ENSMUSG00000053453 0.514300775319626 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Zfp472 ENSMUSG00000053600 1 1 0.853801250889739 1 0.780851835278818 1
Zfp867 ENSMUSG00000054519 0.254414773803597 0.450143880930327 0.514934023620345 0.514934023620345 0.300095920620218 0.450143880930327
Zfp93 ENSMUSG00000055305 0.78148726569172 0.782117202022501 0.782117202022501 0.782117202022501 0.148115998140416 0.444347994421247
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Cnot10 ENSMUSG00000056167 0.400265374208515 0.667674500503417 0.445116333668945 0.667674500503417 0.850151080737202 0.850151080737202
Rbbp4 ENSMUSG00000057236 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.710001140920767 0.926333123228344
Snrpg ENSMUSG00000057278 0.294820734456232 0.512471536058169 0.341647690705446 0.512471536058169 0.513026869856283 0.513026869856283
Zfp53 ENSMUSG00000057409 0.926550375688041 0.926550375688041 0.92622377157404 0.926550375688041 0.573498913947369 0.926550375688041
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Mamld1 ENSMUSG00000059401 0.148772260628989 0.268874530827074 0.17924968721805 0.268874530827074 0.78180291566155 0.78180291566155
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Tmem219 ENSMUSG00000060538 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.926003599371281 0.92622377157404
Zfp873 ENSMUSG00000061371 0.578113371816017 0.926550375688041 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Zfp28 ENSMUSG00000062861 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Zfp938 ENSMUSG00000062931 0.451840588205062 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Med14 ENSMUSG00000064127 0.0746183450292887 0.223855035087866 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152
Zfp69 ENSMUSG00000064141 0.346527959006435 0.346527959006435 0.294820734456232 0.346527959006435 0.214037080764326 0.346527959006435
Zfp772 ENSMUSG00000066838 0.853480389728993 0.853480389728993 0.514934023620345 0.772401035430517 0.514934023620345 0.772401035430517
Hdac8 ENSMUSG00000067567 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041 0.78180291566155 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Hist2h2be ENSMUSG00000068854 0.5155648232968 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620345 0.576973746230334
Hist1h3e ENSMUSG00000069273 1 1 0.425393263482292 1 0.922060259310211 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Srsf3 ENSMUSG00000071172 0.926658283600152 0.926658283600152 0.780851835278818 0.926658283600152 0.710416009055326 0.926658283600152
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Zfp791 ENSMUSG00000074194 0.0449262652924809 0.134778795877443 0.78180291566155 0.78180291566155 0.346899083932133 0.520348625898199
Zfp382 ENSMUSG00000074220 0.456305241393103 0.684457862089655 0.399548817627028 0.684457862089655 0.853801250889739 0.853801250889739
Zfp94 ENSMUSG00000074282 0.514934023620345 0.772401035430517 0.0763619660358786 0.229085898107636 1 1
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544
U2af1l4 ENSMUSG00000078765 0.0566379395854602 0.169913818756381 0.148772260628989 0.223158390943483 0.781170242226513 0.781170242226513
Gm14322 ENSMUSG00000078864 0.711240436189781 0.711650020253571 0.711650020253571 0.711650020253571 0.577259514257969 0.711650020253571
Gm6710 ENSMUSG00000078887 0.925669613555092 0.925669613555092 0.21549027811633 0.64647083434899 0.851061028660105 0.925669613555092
Gm14391 ENSMUSG00000078903 0.214037080764326 0.642111242292977 0.577259514257969 0.711240436189781 0.711240436189781 0.711240436189781
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Zfp703 ENSMUSG00000085795 0.455625354715449 0.57466664340579 0.295581119060361 0.57466664340579 0.57466664340579 0.57466664340579
Lamtor5 ENSMUSG00000087260 0.514934023620345 0.772401035430517 0.34837756124189 0.772401035430517 0.926658283600152 0.926658283600152
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Snrpe ENSMUSG00000090553 0.78180291566155 0.78180291566155 0.399548817627028 0.78180291566155 0.78180291566155 0.78180291566155
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1
Gm20422 ENSMUSG00000092544 0.643606811957488 0.643606811957488 0.0955908182073974 0.286772454622192 0.577829325134931 0.643606811957488
Med20 ENSMUSG00000092558 0.642366752097095 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Gm14325 ENSMUSG00000095362 0.926550375688041 0.926550375688041 0.344663224299303 0.926550375688041 0.643853282854191 0.926550375688041
Zfp433 ENSMUSG00000096795 0.711854160331342 0.78148726569172 0.78148726569172 0.78148726569172 0.45596561163947 0.78148726569172
Zfp87 ENSMUSG00000097333 0.454600801949285 0.681901202923927 0.345410946355104 0.681901202923927 0.853694531487825 0.853694531487825

APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2m ENSMUSG00000005575 0.456305241393103 0.456305241393103 0.180293335960318 0.449023590082343 0.299349060054895 0.449023590082343
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

NIK–>noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2m ENSMUSG00000005575 0.456305241393103 0.456305241393103 0.180293335960318 0.449023590082343 0.299349060054895 0.449023590082343
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Cellular response to hypoxia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Cul2 ENSMUSG00000024231 0.711650020253571 0.711650020253571 0.177853449259986 0.533560347779958 0.643853282854191 0.711650020253571
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Wtip ENSMUSG00000036459 0.926441990075769 0.926441990075769 0.578396848531894 0.926441990075769 0.711854160331342 0.926441990075769
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Displacement of DNA glycosylase by APEX1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mpg ENSMUSG00000020287 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.643853282854191 0.643853282854191
Mutyh ENSMUSG00000028687 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152 0.926550375688041 0.926658283600152
Ogg1 ENSMUSG00000030271 0.213307944885796 0.639923834657388 0.706831781264721 0.706831781264721 0.509144723230069 0.706831781264721
Smug1 ENSMUSG00000036061 0.447265995733381 0.641867098978197 0.641867098978197 0.641867098978197 0.395196379647461 0.641867098978197
Nthl1 ENSMUSG00000041429 0.78148726569172 1 0.643853282854191 1 1 1

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

GLI3 is processed to GLI3R by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Synthesis of glycosylphosphatidylinositol (GPI)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pigyl ENSMUSG00000010607 0.148115998140415 0.444347994421246 0.572616808177226 0.85117361048289 0.85117361048289 0.85117361048289
Pigp ENSMUSG00000022940 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Pigx ENSMUSG00000023791 0.853480389728993 0.853480389728993 0.708745765211584 0.853480389728993 0.21549027811633 0.64647083434899
Pigf ENSMUSG00000024145 0.45596561163947 0.683948417459205 0.853801250889739 0.853801250889739 0.0443599545252853 0.133079863575856
Pigc ENSMUSG00000026698 0.853694531487825 0.853694531487825 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Dpm2 ENSMUSG00000026810 0.148772260628989 0.446316781886968 0.45596561163947 0.683948417459205 0.78148726569172 0.78148726569172
Pigw ENSMUSG00000045140 0.706616781330066 0.706616781330066 0.178901132102685 0.441659526834679 0.294439684556453 0.441659526834679

MAP3K8 (TPL2)-dependent MAPK1/3 activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Tnip2 ENSMUSG00000059866 0.118714930081337 0.35614479024401 0.456305241393103 0.643359829732651 0.643359829732651 0.643359829732651
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp385a ENSMUSG00000000552 0.92416823462528 0.92416823462528 0.398108175780842 0.763717084845103 0.509144723230069 0.763717084845103
Sox9 ENSMUSG00000000567 0.254414773803597 0.707899741868332 0.511097249598474 0.707899741868332 0.707899741868332 0.707899741868332
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Med6 ENSMUSG00000002679 0.853372965654504 1 1 1 0.575824878403157 1
Prdx2 ENSMUSG00000005161 0.712057867818062 1 0.45596561163947 1 1 1
Ttc5 ENSMUSG00000006288 0.710001140920767 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Med8 ENSMUSG00000006392 0.5155648232968 0.643853282854191 0.514300775319626 0.643853282854191 0.643853282854191 0.643853282854191
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Supt4a ENSMUSG00000020485 0.295581119060361 0.443371678590541 0.120850531362929 0.362551594088788 0.508488713161374 0.508488713161374
Med31 ENSMUSG00000020801 0.147458757705094 0.442376273115283 0.711240436189781 0.926658283600152 0.926658283600152 0.926658283600152
Nr1d1 ENSMUSG00000020889 0.643853282854191 0.965779924281287 0.255901190956604 0.767703572869811 1 1
Esr2 ENSMUSG00000021055 0.21549027811633 0.64647083434899 0.450094379653806 0.675141569480709 0.85326530496423 0.85326530496423
Ppm1a ENSMUSG00000021096 0.120850531362929 0.362551594088788 0.643359829732651 0.711240436189781 0.711240436189781 0.711240436189781
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Myc ENSMUSG00000022346 0.34837756124189 0.769540304784424 0.513026869856283 0.769540304784424 0.853801250889739 0.853801250889739
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Ring1 ENSMUSG00000024325 0.342026805366747 0.51304020805012 0.776243028387552 0.776243028387552 0.118714930081337 0.35614479024401
Slmo1 ENSMUSG00000024530 0.11993617140438 0.359808514213139 0.780851835278818 0.78148726569172 0.78148726569172 0.78148726569172
Nedd4l ENSMUSG00000024589 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155 0.21549027811633 0.64647083434899
Pcgf6 ENSMUSG00000025050 0.852504981253341 0.852504981253341 0.641867098978198 0.852504981253341 0.514934023620345 0.852504981253341
Cbx8 ENSMUSG00000025578 0.0331400397096515 0.0497100595644772 0.00247508107184991 0.00742524321554974 0.782117202022501 0.782117202022501
Zfp202 ENSMUSG00000025602 0.643359829732651 0.852832278580641 0.514934023620345 0.852832278580641 0.852832278580641 0.852832278580641
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Ssrp1 ENSMUSG00000027067 0.78180291566155 0.78180291566155 0.0116356061791785 0.0349068185375355 0.575536202757516 0.78180291566155
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Lef1 ENSMUSG00000027985 0.711034989117171 0.711034989117171 0.347639524025037 0.683438032073173 0.455625354715448 0.683438032073173
Lamtor2 ENSMUSG00000028062 0.453570536021945 0.454600801949285 0.0766111619812296 0.229833485943689 0.454600801949285 0.454600801949285
Prdx1 ENSMUSG00000028691 0.926658283600152 0.926658283600152 0.78148726569172 0.926658283600152 0.710208797518812 0.926658283600152
Taf12 ENSMUSG00000028899 0.0238002551499929 0.0714007654499788 0.576973746230334 0.576973746230334 0.453225835454266 0.576973746230334
Zkscan14 ENSMUSG00000029627 0.398108175780842 0.575536202757516 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Auts2 ENSMUSG00000029673 0.452880492349546 0.679320738524319 0.146141353215796 0.438424059647387 0.92589277149125 0.92589277149125
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Casp2 ENSMUSG00000029863 0.926333123228344 0.926333123228344 0.348008842235184 0.867170057724026 0.578113371816017 0.867170057724026
Zfp248 ENSMUSG00000030145 0.214764523938594 0.21549027811633 0.0321889748775514 0.0965669246326542 0.21549027811633 0.21549027811633
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Zfp626 ENSMUSG00000030604 0.511742979522636 0.710001140920767 0.710001140920767 0.710001140920767 0.211844580334808 0.635533741004424
Hdac6 ENSMUSG00000031161 0.573498913947369 0.578113371816017 0.344663224299303 0.578113371816017 0.578113371816017 0.578113371816017
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ehmt1 ENSMUSG00000036893 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.514934023620344 0.853801250889739
H2afz ENSMUSG00000037894 0.852832278580641 1 0.454942951775342 1 1 1
Sesn1 ENSMUSG00000038332 0.347639524025037 0.853587578053106 0.852395395941406 0.853587578053106 0.853587578053106 0.853587578053106
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Cnot4 ENSMUSG00000038784 0.0579478375430677 0.173843512629203 0.782117202022501 0.782117202022501 0.398829756175299 0.598244634262948
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Krba1 ENSMUSG00000042810 0.216214347033995 0.648643041101985 0.926658283600152 0.926658283600152 0.853907737111068 0.926658283600152
Zfp784 ENSMUSG00000043290 0.0969812105731562 0.290943631719469 0.926658283600152 1 1 1
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Hist1h2be ENSMUSG00000047246 0.711854160331342 0.711854160331342 0.148772260628989 0.446316781886968 0.711854160331342 0.711854160331342
Tgif1 ENSMUSG00000047407 0.255901190956604 0.383851786434905 0.00768144932639892 0.0230443479791968 0.782117202022501 0.782117202022501
Lamtor4 ENSMUSG00000050552 0.177153312234059 0.531459936702178 0.393724994268831 0.590587491403246 0.708323672944427 0.708323672944427
Zfp169 ENSMUSG00000050954 0.0743693776059065 0.223108132817719 0.852832278580641 0.852832278580641 0.453570536021945 0.680355804032917
Zfp11 ENSMUSG00000051034 0.0958690133561599 0.220200812784373 0.643359829732651 0.643359829732651 0.146800541856249 0.220200812784373
Zfp472 ENSMUSG00000053600 1 1 0.853801250889739 1 0.780851835278818 1
Zfp867 ENSMUSG00000054519 0.254414773803597 0.450143880930327 0.514934023620345 0.514934023620345 0.300095920620218 0.450143880930327
Zfp93 ENSMUSG00000055305 0.78148726569172 0.782117202022501 0.782117202022501 0.782117202022501 0.148115998140416 0.444347994421247
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Cnot10 ENSMUSG00000056167 0.400265374208515 0.667674500503417 0.445116333668945 0.667674500503417 0.850151080737202 0.850151080737202
Rbbp4 ENSMUSG00000057236 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.710001140920767 0.926333123228344
Zfp53 ENSMUSG00000057409 0.926550375688041 0.926550375688041 0.92622377157404 0.926550375688041 0.573498913947369 0.926550375688041
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Mamld1 ENSMUSG00000059401 0.148772260628989 0.268874530827074 0.17924968721805 0.268874530827074 0.78180291566155 0.78180291566155
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Tmem219 ENSMUSG00000060538 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.926003599371281 0.92622377157404
Zfp873 ENSMUSG00000061371 0.578113371816017 0.926550375688041 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Zfp28 ENSMUSG00000062861 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Zfp938 ENSMUSG00000062931 0.451840588205062 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Med14 ENSMUSG00000064127 0.0746183450292887 0.223855035087866 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152
Zfp69 ENSMUSG00000064141 0.346527959006435 0.346527959006435 0.294820734456232 0.346527959006435 0.214037080764326 0.346527959006435
Zfp772 ENSMUSG00000066838 0.853480389728993 0.853480389728993 0.514934023620345 0.772401035430517 0.514934023620345 0.772401035430517
Hdac8 ENSMUSG00000067567 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041 0.78180291566155 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Hist2h2be ENSMUSG00000068854 0.5155648232968 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620345 0.576973746230334
Hist1h3e ENSMUSG00000069273 1 1 0.425393263482292 1 0.922060259310211 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Zfp791 ENSMUSG00000074194 0.0449262652924809 0.134778795877443 0.78180291566155 0.78180291566155 0.346899083932133 0.520348625898199
Zfp382 ENSMUSG00000074220 0.456305241393103 0.684457862089655 0.399548817627028 0.684457862089655 0.853801250889739 0.853801250889739
Zfp94 ENSMUSG00000074282 0.514934023620345 0.772401035430517 0.0763619660358786 0.229085898107636 1 1
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544
Gm14322 ENSMUSG00000078864 0.711240436189781 0.711650020253571 0.711650020253571 0.711650020253571 0.577259514257969 0.711650020253571
Gm6710 ENSMUSG00000078887 0.925669613555092 0.925669613555092 0.21549027811633 0.64647083434899 0.851061028660105 0.925669613555092
Gm14391 ENSMUSG00000078903 0.214037080764326 0.642111242292977 0.577259514257969 0.711240436189781 0.711240436189781 0.711240436189781
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Zfp703 ENSMUSG00000085795 0.455625354715449 0.57466664340579 0.295581119060361 0.57466664340579 0.57466664340579 0.57466664340579
Lamtor5 ENSMUSG00000087260 0.514934023620345 0.772401035430517 0.34837756124189 0.772401035430517 0.926658283600152 0.926658283600152
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1
Gm20422 ENSMUSG00000092544 0.643606811957488 0.643606811957488 0.0955908182073974 0.286772454622192 0.577829325134931 0.643606811957488
Med20 ENSMUSG00000092558 0.642366752097095 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Gm14325 ENSMUSG00000095362 0.926550375688041 0.926550375688041 0.344663224299303 0.926550375688041 0.643853282854191 0.926550375688041
Zfp433 ENSMUSG00000096795 0.711854160331342 0.78148726569172 0.78148726569172 0.78148726569172 0.45596561163947 0.78148726569172
Zfp87 ENSMUSG00000097333 0.454600801949285 0.681901202923927 0.345410946355104 0.681901202923927 0.853694531487825 0.853694531487825

CDK-mediated phosphorylation and removal of Cdc6

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp385a ENSMUSG00000000552 0.92416823462528 0.92416823462528 0.398108175780842 0.763717084845103 0.509144723230069 0.763717084845103
Sox9 ENSMUSG00000000567 0.254414773803597 0.707899741868332 0.511097249598474 0.707899741868332 0.707899741868332 0.707899741868332
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Med6 ENSMUSG00000002679 0.853372965654504 1 1 1 0.575824878403157 1
Prkra ENSMUSG00000002731 0.177153312234059 0.531459936702178 0.501096336601183 0.573205482926791 0.573205482926791 0.573205482926791
Prdx2 ENSMUSG00000005161 0.712057867818062 1 0.45596561163947 1 1 1
Ddx39 ENSMUSG00000005481 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.578113371816017 0.853801250889739
Ttc5 ENSMUSG00000006288 0.710001140920767 0.926333123228344 0.34837756124189 0.926333123228344 0.926333123228344 0.926333123228344
Med8 ENSMUSG00000006392 0.5155648232968 0.643853282854191 0.514300775319626 0.643853282854191 0.643853282854191 0.643853282854191
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Surf1 ENSMUSG00000015790 0.398829756175299 0.926441990075769 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Ints2 ENSMUSG00000018068 0.578113371816017 0.781170242226513 0.148115998140415 0.444347994421246 0.781170242226513 0.781170242226513
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Supt4a ENSMUSG00000020485 0.295581119060361 0.443371678590541 0.120850531362929 0.362551594088788 0.508488713161374 0.508488713161374
Med31 ENSMUSG00000020801 0.147458757705094 0.442376273115283 0.711240436189781 0.926658283600152 0.926658283600152 0.926658283600152
Nr1d1 ENSMUSG00000020889 0.643853282854191 0.965779924281287 0.255901190956604 0.767703572869811 1 1
Esr2 ENSMUSG00000021055 0.21549027811633 0.64647083434899 0.450094379653806 0.675141569480709 0.85326530496423 0.85326530496423
Ppm1a ENSMUSG00000021096 0.120850531362929 0.362551594088788 0.643359829732651 0.711240436189781 0.711240436189781 0.711240436189781
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Myc ENSMUSG00000022346 0.34837756124189 0.769540304784424 0.513026869856283 0.769540304784424 0.853801250889739 0.853801250889739
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Cox14 ENSMUSG00000023020 0.779888212132595 0.779888212132595 0.509144723230069 0.779888212132595 0.779238691542963 0.779888212132595
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Lrpprc ENSMUSG00000024120 0.710001140920767 0.710001140920767 0.0523032931247597 0.156909879374279 0.573498913947369 0.710001140920767
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Ring1 ENSMUSG00000024325 0.342026805366747 0.51304020805012 0.776243028387552 0.776243028387552 0.118714930081337 0.35614479024401
Slmo1 ENSMUSG00000024530 0.11993617140438 0.359808514213139 0.780851835278818 0.78148726569172 0.78148726569172 0.78148726569172
Nedd4l ENSMUSG00000024589 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155 0.21549027811633 0.64647083434899
Pcgf6 ENSMUSG00000025050 0.852504981253341 0.852504981253341 0.641867098978198 0.852504981253341 0.514934023620345 0.852504981253341
Ints4 ENSMUSG00000025133 0.173632433887832 0.520897301663497 0.78180291566155 0.78180291566155 0.573791743469336 0.78180291566155
Cbx8 ENSMUSG00000025578 0.0331400397096515 0.0497100595644772 0.00247508107184991 0.00742524321554974 0.782117202022501 0.782117202022501
Zfp202 ENSMUSG00000025602 0.643359829732651 0.852832278580641 0.514934023620345 0.852832278580641 0.852832278580641 0.852832278580641
Cox20 ENSMUSG00000026500 0.78180291566155 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Ssrp1 ENSMUSG00000027067 0.78180291566155 0.78180291566155 0.0116356061791785 0.0349068185375355 0.575536202757516 0.78180291566155
Clp1 ENSMUSG00000027079 0.577259514257969 0.865889271386954 0.577259514257969 0.865889271386954 0.92622377157404 0.92622377157404
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Polr1b ENSMUSG00000027395 0.01710279005982 0.0513083701794599 0.293293089483362 0.439939634225043 0.852832278580641 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Lef1 ENSMUSG00000027985 0.711034989117171 0.711034989117171 0.347639524025037 0.683438032073173 0.455625354715448 0.683438032073173
Lamtor2 ENSMUSG00000028062 0.453570536021945 0.454600801949285 0.0766111619812296 0.229833485943689 0.454600801949285 0.454600801949285
Magoh ENSMUSG00000028609 0.92622377157404 0.92622377157404 0.710208797518812 0.92622377157404 0.710208797518812 0.92622377157404
Prdx1 ENSMUSG00000028691 0.926658283600152 0.926658283600152 0.78148726569172 0.926658283600152 0.710208797518812 0.926658283600152
Taf12 ENSMUSG00000028899 0.0238002551499929 0.0714007654499788 0.576973746230334 0.576973746230334 0.453225835454266 0.576973746230334
Cpsf3l ENSMUSG00000029034 0.395928178642446 0.593892267963669 0.0763619660358787 0.229085898107636 0.926333123228344 0.926333123228344
Srsf9 ENSMUSG00000029538 0.214764523938594 0.644293571815781 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Zkscan14 ENSMUSG00000029627 0.398108175780842 0.575536202757516 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516
Ndufa4 ENSMUSG00000029632 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898 0.926333123228344 0.926550375688041
Auts2 ENSMUSG00000029673 0.452880492349546 0.679320738524319 0.146141353215796 0.438424059647387 0.92589277149125 0.92589277149125
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Casp2 ENSMUSG00000029863 0.926333123228344 0.926333123228344 0.348008842235184 0.867170057724026 0.578113371816017 0.867170057724026
Zfp248 ENSMUSG00000030145 0.214764523938594 0.21549027811633 0.0321889748775514 0.0965669246326542 0.21549027811633 0.21549027811633
Sec13 ENSMUSG00000030298 0.782117202022501 0.853372965654504 0.643853282854191 0.853372965654504 0.853372965654504 0.853372965654504
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Zfp626 ENSMUSG00000030604 0.511742979522636 0.710001140920767 0.710001140920767 0.710001140920767 0.211844580334808 0.635533741004424
Polr3e ENSMUSG00000030880 0.575536202757516 0.643359829732651 0.299349060054895 0.643359829732651 0.643359829732651 0.643359829732651
Hdac6 ENSMUSG00000031161 0.573498913947369 0.578113371816017 0.344663224299303 0.578113371816017 0.578113371816017 0.578113371816017
Cox7b ENSMUSG00000031231 0.7802108304765 0.7802108304765 0.254414773803597 0.592794569471191 0.395196379647461 0.592794569471191
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Taf1c ENSMUSG00000031832 0.300095920620218 0.450143880930327 0.148115998140416 0.444347994421247 0.782117202022501 0.782117202022501
Gtf2a2 ENSMUSG00000033543 0.514934023620345 0.643359829732651 0.643359829732651 0.643359829732651 0.178901132102685 0.536703396308054
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Nup37 ENSMUSG00000035351 0.853801250889739 0.853801250889739 0.511742979522636 0.853801250889739 0.853372965654504 0.853801250889739
Cox8a ENSMUSG00000035885 0.628654363853655 0.628654363853655 0.283930443883615 0.425895665825422 0.0419238354397911 0.125771506319373
Snapc4 ENSMUSG00000036281 0.180293335960318 0.540880007880955 0.711650020253571 0.711650020253571 0.45596561163947 0.683948417459205
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Znrd1 ENSMUSG00000036315 0.578113371816017 0.711854160331342 0.577829325134931 0.711854160331342 0.711854160331342 0.711854160331342
Cox6b1 ENSMUSG00000036751 0.454600801949285 0.681901202923927 0.255901190956604 0.681901202923927 0.926333123228344 0.926333123228344
Ehmt1 ENSMUSG00000036893 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.514934023620344 0.853801250889739
H2afz ENSMUSG00000037894 0.852832278580641 1 0.454942951775342 1 1 1
Sesn1 ENSMUSG00000038332 0.347639524025037 0.853587578053106 0.852395395941406 0.853587578053106 0.853587578053106 0.853587578053106
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Nup205 ENSMUSG00000038759 0.214037080764326 0.642111242292977 0.712057867818062 0.853694531487825 0.853694531487825 0.853694531487825
Cnot4 ENSMUSG00000038784 0.0579478375430677 0.173843512629203 0.782117202022501 0.782117202022501 0.398829756175299 0.598244634262948
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Rprd1a ENSMUSG00000040446 0.399548817627028 0.599323226440542 0.148115998140416 0.444347994421247 0.712057867818062 0.712057867818062
Krba1 ENSMUSG00000042810 0.216214347033995 0.648643041101985 0.926658283600152 0.926658283600152 0.853907737111068 0.926658283600152
Zfp784 ENSMUSG00000043290 0.0969812105731562 0.290943631719469 0.926658283600152 1 1 1
Cox19 ENSMUSG00000045438 0.853480389728993 0.853480389728993 0.511742979522636 0.853480389728993 0.709375484777034 0.853480389728993
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Csnk2a2 ENSMUSG00000046707 0.513026869856283 0.769540304784424 0.513026869856283 0.769540304784424 0.7802108304765 0.7802108304765
Hist1h2be ENSMUSG00000047246 0.711854160331342 0.711854160331342 0.148772260628989 0.446316781886968 0.711854160331342 0.711854160331342
Tgif1 ENSMUSG00000047407 0.255901190956604 0.383851786434905 0.00768144932639892 0.0230443479791968 0.782117202022501 0.782117202022501
Lamtor4 ENSMUSG00000050552 0.177153312234059 0.531459936702178 0.393724994268831 0.590587491403246 0.708323672944427 0.708323672944427
Zfp169 ENSMUSG00000050954 0.0743693776059065 0.223108132817719 0.852832278580641 0.852832278580641 0.453570536021945 0.680355804032917
Zfp11 ENSMUSG00000051034 0.0958690133561599 0.220200812784373 0.643359829732651 0.643359829732651 0.146800541856249 0.220200812784373
Pom121 ENSMUSG00000053293 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Thoc7 ENSMUSG00000053453 0.514300775319626 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Zfp472 ENSMUSG00000053600 1 1 0.853801250889739 1 0.780851835278818 1
Zfp867 ENSMUSG00000054519 0.254414773803597 0.450143880930327 0.514934023620345 0.514934023620345 0.300095920620218 0.450143880930327
Zfp93 ENSMUSG00000055305 0.78148726569172 0.782117202022501 0.782117202022501 0.782117202022501 0.148115998140416 0.444347994421247
Tceb2 ENSMUSG00000055839 0.454600801949285 0.681901202923927 0.348008842235184 0.681901202923927 0.92622377157404 0.92622377157404
Cnot10 ENSMUSG00000056167 0.400265374208515 0.667674500503417 0.445116333668945 0.667674500503417 0.850151080737202 0.850151080737202
Rbbp4 ENSMUSG00000057236 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344 0.710001140920767 0.926333123228344
Snrpg ENSMUSG00000057278 0.294820734456232 0.512471536058169 0.341647690705446 0.512471536058169 0.513026869856283 0.513026869856283
Zfp53 ENSMUSG00000057409 0.926550375688041 0.926550375688041 0.92622377157404 0.926550375688041 0.573498913947369 0.926550375688041
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Mamld1 ENSMUSG00000059401 0.148772260628989 0.268874530827074 0.17924968721805 0.268874530827074 0.78180291566155 0.78180291566155
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Tmem219 ENSMUSG00000060538 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.926003599371281 0.92622377157404
Zfp873 ENSMUSG00000061371 0.578113371816017 0.926550375688041 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Zfp28 ENSMUSG00000062861 0.347639524025037 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Zfp938 ENSMUSG00000062931 0.451840588205062 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Med14 ENSMUSG00000064127 0.0746183450292887 0.223855035087866 0.926658283600152 0.926658283600152 0.711854160331342 0.926658283600152
Zfp69 ENSMUSG00000064141 0.346527959006435 0.346527959006435 0.294820734456232 0.346527959006435 0.214037080764326 0.346527959006435
Zfp772 ENSMUSG00000066838 0.853480389728993 0.853480389728993 0.514934023620345 0.772401035430517 0.514934023620345 0.772401035430517
Hdac8 ENSMUSG00000067567 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041 0.78180291566155 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Hist2h2be ENSMUSG00000068854 0.5155648232968 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620345 0.576973746230334
Hist1h3e ENSMUSG00000069273 1 1 0.425393263482292 1 0.922060259310211 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Srsf3 ENSMUSG00000071172 0.926658283600152 0.926658283600152 0.780851835278818 0.926658283600152 0.710416009055326 0.926658283600152
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Zfp791 ENSMUSG00000074194 0.0449262652924809 0.134778795877443 0.78180291566155 0.78180291566155 0.346899083932133 0.520348625898199
Zfp382 ENSMUSG00000074220 0.456305241393103 0.684457862089655 0.399548817627028 0.684457862089655 0.853801250889739 0.853801250889739
Zfp94 ENSMUSG00000074282 0.514934023620345 0.772401035430517 0.0763619660358786 0.229085898107636 1 1
Ywhaq ENSMUSG00000076432 0.0315593554855452 0.0946780664566355 0.246861959455465 0.370292939183197 0.778911768167544 0.778911768167544
U2af1l4 ENSMUSG00000078765 0.0566379395854602 0.169913818756381 0.148772260628989 0.223158390943483 0.781170242226513 0.781170242226513
Gm14322 ENSMUSG00000078864 0.711240436189781 0.711650020253571 0.711650020253571 0.711650020253571 0.577259514257969 0.711650020253571
Gm6710 ENSMUSG00000078887 0.925669613555092 0.925669613555092 0.21549027811633 0.64647083434899 0.851061028660105 0.925669613555092
Gm14391 ENSMUSG00000078903 0.214037080764326 0.642111242292977 0.577259514257969 0.711240436189781 0.711240436189781 0.711240436189781
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Tceb1 ENSMUSG00000079658 0.454600801949285 0.681901202923927 0.297095062262362 0.681901202923927 0.852175490580835 0.852175490580835
Zfp703 ENSMUSG00000085795 0.455625354715449 0.57466664340579 0.295581119060361 0.57466664340579 0.57466664340579 0.57466664340579
Lamtor5 ENSMUSG00000087260 0.514934023620345 0.772401035430517 0.34837756124189 0.772401035430517 0.926658283600152 0.926658283600152
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Snrpe ENSMUSG00000090553 0.78180291566155 0.78180291566155 0.399548817627028 0.78180291566155 0.78180291566155 0.78180291566155
Cox16 ENSMUSG00000091803 0.926658283600152 1 0.643359829732651 1 1 1
Gm20422 ENSMUSG00000092544 0.643606811957488 0.643606811957488 0.0955908182073974 0.286772454622192 0.577829325134931 0.643606811957488
Med20 ENSMUSG00000092558 0.642366752097095 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Gm14325 ENSMUSG00000095362 0.926550375688041 0.926550375688041 0.344663224299303 0.926550375688041 0.643853282854191 0.926550375688041
Zfp433 ENSMUSG00000096795 0.711854160331342 0.78148726569172 0.78148726569172 0.78148726569172 0.45596561163947 0.78148726569172
Zfp87 ENSMUSG00000097333 0.454600801949285 0.681901202923927 0.345410946355104 0.681901202923927 0.853694531487825 0.853694531487825

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Mitochondrial translation elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl49 ENSMUSG00000007338 0.853049270252403 0.853049270252403 0.0575107614292585 0.172532284287776 0.576973746230334 0.853049270252403
Mrpl52 ENSMUSG00000010406 0.147458757705095 0.442376273115284 1 1 0.572616808177226 0.85892521226584
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Ict1 ENSMUSG00000018858 0.454942951775341 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Mrpl39 ENSMUSG00000022889 0.00289311433957183 0.00867934301871548 0.452880492349546 0.452880492349546 0.299349060054895 0.449023590082343
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Mrpl51 ENSMUSG00000030335 0.575824878403157 0.863737317604735 0.216214347033995 0.648643041101984 1 1
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Mrps28 ENSMUSG00000040269 0.454942951775341 0.924405146515181 0.924405146515181 0.924405146515181 0.635703516568382 0.924405146515181
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Chchd1 ENSMUSG00000063787 0.78180291566155 0.926333123228344 0.400265374208515 0.926333123228344 0.926333123228344 0.926333123228344
Dap3 ENSMUSG00000068921 1 1 0.0930846407079412 0.279253922123823 0.514934023620345 0.772401035430517

Iron uptake and transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tcirg1 ENSMUSG00000001750 0.255530331334266 0.596076093399921 0.397384062266614 0.596076093399921 0.924872384323463 0.924872384323463
Hmox1 ENSMUSG00000005413 0.00253244992826164 0.00759734978478493 0.447621891168214 0.67143283675232 0.926333123228344 0.926333123228344
Nedd8 ENSMUSG00000010376 0.926003599371282 0.926003599371282 0.0953125666339397 0.285937699901819 0.640861491578951 0.926003599371282
Atp6v0e ENSMUSG00000015575 0.577829325134931 0.866743987702397 0.92589277149125 0.92589277149125 0.577259514257969 0.866743987702397
Atp6v0a1 ENSMUSG00000019302 0.711650020253571 0.711854160331342 0.711034989117171 0.711854160331342 0.711854160331342 0.711854160331342
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Tfrc ENSMUSG00000022797 0.701310685803632 0.85117361048289 0.85117361048289 0.85117361048289 0.634645058916812 0.85117361048289
Slc11a2 ENSMUSG00000023030 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.642366752097095 0.926658283600152
Atp6v1g2 ENSMUSG00000024403 0.643853282854191 0.782117202022501 0.782117202022501 0.782117202022501 0.5155648232968 0.782117202022501
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Mfsd7b ENSMUSG00000066595 0.17924968721805 0.537749061654149 0.781170242226513 1 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Recognition of DNA damage by PCNA-containing replication complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

DNA Replication Pre-Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Gmnn ENSMUSG00000006715 0.926550375688041 0.926550375688041 0.397384062266614 0.596076093399921 0.0583853430099098 0.175156029029729
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Cdc7 ENSMUSG00000029283 0.853694531487825 0.853694531487825 0.398829756175299 0.598244634262948 0.347639524025037 0.598244634262948
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

HDR through Homologous Recombination (HRR)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Mus81 ENSMUSG00000024906 0.0936419271039908 0.280925781311972 0.711034989117171 0.711034989117171 0.710208797518812 0.711034989117171
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Xrcc2 ENSMUSG00000028933 0.78180291566155 1 0.926658283600152 1 1 1
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Slx4 ENSMUSG00000039738 0.45596561163947 0.45596561163947 0.0743693776059065 0.223108132817719 0.345037391052887 0.45596561163947
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Spidr ENSMUSG00000041974 0.642864324224729 0.642864324224729 0.514934023620345 0.642864324224729 0.57113445032749 0.642864324224729
Palb2 ENSMUSG00000044702 0.853801250889739 1 0.926550375688041 1 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Hspa1b ENSMUSG00000090877 0.214037080764326 0.642111242292977 0.852832278580641 0.852832278580641 0.643853282854191 0.852832278580641

DNA Damage Bypass

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Rchy1 ENSMUSG00000029397 0.454942951775341 1 0.711854160331342 1 1 1
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Resolution of Abasic Sites (AP sites)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mpg ENSMUSG00000020287 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.643853282854191 0.643853282854191
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Mutyh ENSMUSG00000028687 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152 0.926550375688041 0.926658283600152
Ogg1 ENSMUSG00000030271 0.213307944885796 0.639923834657388 0.706831781264721 0.706831781264721 0.509144723230069 0.706831781264721
Smug1 ENSMUSG00000036061 0.447265995733381 0.641867098978197 0.641867098978197 0.641867098978197 0.395196379647461 0.641867098978197
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Nthl1 ENSMUSG00000041429 0.78148726569172 1 0.643853282854191 1 1 1

Translesion Synthesis by POLH

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Rchy1 ENSMUSG00000029397 0.454942951775341 1 0.711854160331342 1 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Mitochondrial translation termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl49 ENSMUSG00000007338 0.853049270252403 0.853049270252403 0.0575107614292585 0.172532284287776 0.576973746230334 0.853049270252403
Mrpl52 ENSMUSG00000010406 0.147458757705095 0.442376273115284 1 1 0.572616808177226 0.85892521226584
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Ict1 ENSMUSG00000018858 0.454942951775341 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Mrpl39 ENSMUSG00000022889 0.00289311433957183 0.00867934301871548 0.452880492349546 0.452880492349546 0.299349060054895 0.449023590082343
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Mrpl51 ENSMUSG00000030335 0.575824878403157 0.863737317604735 0.216214347033995 0.648643041101984 1 1
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Mrps28 ENSMUSG00000040269 0.454942951775341 0.924405146515181 0.924405146515181 0.924405146515181 0.635703516568382 0.924405146515181
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Chchd1 ENSMUSG00000063787 0.78180291566155 0.926333123228344 0.400265374208515 0.926333123228344 0.926333123228344 0.926333123228344
Dap3 ENSMUSG00000068921 1 1 0.0930846407079412 0.279253922123823 0.514934023620345 0.772401035430517

Termination of translesion DNA synthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

DNA Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppp5c ENSMUSG00000003099 0.577829325134931 0.640861491578951 0.116265430850263 0.34879629255079 0.640861491578951 0.640861491578951
Ercc1 ENSMUSG00000003549 0.214037080764326 0.321055621146488 0.146800541856249 0.321055621146488 0.78180291566155 0.78180291566155
Fancl ENSMUSG00000004018 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.148772260628989 0.446316781886968
Eya4 ENSMUSG00000010461 0.926550375688041 0.926550375688041 0.11810342389482 0.354310271684459 0.642864324224729 0.926550375688041
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Mpg ENSMUSG00000020287 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.643853282854191 0.643853282854191
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Fancc ENSMUSG00000021461 0.455965611639471 0.576973746230334 0.340887582990546 0.576973746230334 0.576973746230334 0.576973746230334
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Prkdc ENSMUSG00000022672 0.853801250889739 0.853801250889739 0.572616808177226 0.853801250889739 0.347639524025037 0.853801250889739
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Mus81 ENSMUSG00000024906 0.0936419271039908 0.280925781311972 0.711034989117171 0.711034989117171 0.710208797518812 0.711034989117171
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Rad23b ENSMUSG00000028426 0.0743693776059063 0.223108132817719 0.455625354715449 0.576973746230334 0.576973746230334 0.576973746230334
Fancg ENSMUSG00000028453 0.511742979522636 0.710208797518812 0.710208797518812 0.710208797518812 0.072378961026407 0.217136883079221
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Mutyh ENSMUSG00000028687 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152 0.926550375688041 0.926658283600152
Xrcc2 ENSMUSG00000028933 0.78180291566155 1 0.926658283600152 1 1 1
Rchy1 ENSMUSG00000029397 0.454942951775341 1 0.711854160331342 1 1 1
Rad52 ENSMUSG00000030166 0.0958690133561599 0.28760704006848 0.642864324224729 0.642864324224729 0.299349060054895 0.449023590082343
Ogg1 ENSMUSG00000030271 0.213307944885796 0.639923834657388 0.706831781264721 0.706831781264721 0.509144723230069 0.706831781264721
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Terf2 ENSMUSG00000031921 0.706831781264721 0.852940894477647 0.0969812105731563 0.290943631719469 0.852940894477647 0.852940894477647
Mlh1 ENSMUSG00000032498 0.0413659913978561 0.124097974193568 0.297848640636702 0.446772960955053 1 1
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Smug1 ENSMUSG00000036061 0.447265995733381 0.641867098978197 0.641867098978197 0.641867098978197 0.395196379647461 0.641867098978197
H2afz ENSMUSG00000037894 0.852832278580641 1 0.454942951775342 1 1 1
Rad9b ENSMUSG00000038569 0.17610058307789 0.50716883916608 0.383900043565238 0.50716883916608 0.50716883916608 0.50716883916608
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Neil3 ENSMUSG00000039396 0.782117202022501 1 1 1 0.255901190956604 0.767703572869812
Slx4 ENSMUSG00000039738 0.45596561163947 0.45596561163947 0.0743693776059065 0.223108132817719 0.345037391052887 0.45596561163947
Exo1 ENSMUSG00000039748 0.851954599472143 0.851954599472143 0.514300775319626 0.771451162979439 0.248007862766527 0.744023588299582
Nthl1 ENSMUSG00000041429 0.78148726569172 1 0.643853282854191 1 1 1
Spidr ENSMUSG00000041974 0.642864324224729 0.642864324224729 0.514934023620345 0.642864324224729 0.57113445032749 0.642864324224729
Palb2 ENSMUSG00000044702 0.853801250889739 1 0.926550375688041 1 1 1
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Hist1h2be ENSMUSG00000047246 0.711854160331342 0.711854160331342 0.148772260628989 0.446316781886968 0.711854160331342 0.711854160331342
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Hist2h2be ENSMUSG00000068854 0.5155648232968 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620345 0.576973746230334
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Rnf8 ENSMUSG00000090083 0.21549027811633 0.45596561163947 0.45596561163947 0.45596561163947 0.398108175780842 0.45596561163947
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Mitochondrial translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl49 ENSMUSG00000007338 0.853049270252403 0.853049270252403 0.0575107614292585 0.172532284287776 0.576973746230334 0.853049270252403
Mrpl52 ENSMUSG00000010406 0.147458757705095 0.442376273115284 1 1 0.572616808177226 0.85892521226584
Mrps18c ENSMUSG00000016833 0.926333123228344 0.926333123228344 0.299349060054895 0.660559389942137 0.440372926628091 0.660559389942137
Ict1 ENSMUSG00000018858 0.454942951775341 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Mrpl39 ENSMUSG00000022889 0.00289311433957183 0.00867934301871548 0.452880492349546 0.452880492349546 0.299349060054895 0.449023590082343
Mrpl27 ENSMUSG00000024414 0.346899083932133 0.399548817627028 0.180293335960318 0.399548817627028 0.399548817627028 0.399548817627028
Mrpl11 ENSMUSG00000024902 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501
Mrpl30 ENSMUSG00000026087 0.392985378348026 0.589478067522039 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105
Mrpl9 ENSMUSG00000028140 0.643359829732651 0.965039744598977 0.177153312234059 0.531459936702178 1 1
Mrpl20 ENSMUSG00000029066 0.509144723230069 0.763717084845103 0.450794830295118 0.763717084845103 0.77858338846904 0.77858338846904
Mrpl51 ENSMUSG00000030335 0.575824878403157 0.863737317604735 0.216214347033995 0.648643041101984 1 1
Mrpl3 ENSMUSG00000032563 0.342405296020881 0.677760882307593 0.78180291566155 0.78180291566155 0.451840588205062 0.677760882307593
Mrpl23 ENSMUSG00000037772 0.642366752097095 0.642366752097095 0.0331400397096514 0.0994201191289543 0.297848640636702 0.446772960955053
Mrps28 ENSMUSG00000040269 0.454942951775341 0.924405146515181 0.924405146515181 0.924405146515181 0.635703516568382 0.924405146515181
Mrps16 ENSMUSG00000049960 0.399548817627028 0.599323226440542 0.299349060054895 0.599323226440542 0.782117202022501 0.782117202022501
Mrps14 ENSMUSG00000058267 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041 0.853801250889739 0.926550375688041
Chchd1 ENSMUSG00000063787 0.78180291566155 0.926333123228344 0.400265374208515 0.926333123228344 0.926333123228344 0.926333123228344
Dap3 ENSMUSG00000068921 1 1 0.0930846407079412 0.279253922123823 0.514934023620345 0.772401035430517

Retrograde transport at the Trans-Golgi-Network

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cog1 ENSMUSG00000018661 0.01710279005982 0.0513083701794599 0.513665062682276 0.770497594023414 1 1
Rhobtb3 ENSMUSG00000021589 0.853801250889739 0.853801250889739 0.514300775319626 0.853801250889739 0.78180291566155 0.853801250889739
Vps52 ENSMUSG00000024319 0.514934023620345 0.710416009055326 0.710416009055326 0.710416009055326 0.578113371816017 0.710416009055326
Vamp4 ENSMUSG00000026696 0.926550375688041 0.926550375688041 0.093084640707941 0.279253922123823 0.84934104438081 0.926550375688041
Stx16 ENSMUSG00000027522 0.851732715229127 0.851732715229127 0.173632433887832 0.520897301663497 0.85117361048289 0.851732715229127
Rgp1 ENSMUSG00000028468 0.780851835278818 0.853801250889739 0.853801250889739 0.853801250889739 0.300095920620218 0.853801250889739
Vamp3 ENSMUSG00000028955 0.453225835454266 0.853480389728993 0.853480389728993 0.853480389728993 0.7802108304765 0.853480389728993
Cog4 ENSMUSG00000031753 0.78148726569172 1 1 1 0.399548817627028 1
Cog2 ENSMUSG00000031979 1 1 0.926550375688041 1 0.455625354715449 1
Arfrp1 ENSMUSG00000038671 0.514934023620344 0.710208797518812 0.45596561163947 0.710208797518812 0.710208797518812 0.710208797518812
Tgoln1 ENSMUSG00000056429 0.0007950941817707 0.0023852825453121 0.175044824745981 0.262567237118971 0.297095062262362 0.297095062262362

Regulation of mitotic cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

APC/C-mediated degradation of cell cycle proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Metabolism of nucleotides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gmpr2 ENSMUSG00000002326 0.505169133438821 0.757753700158231 0.179945789077372 0.539837367232116 1 1
Dguok ENSMUSG00000014554 0.505169133438821 0.757753700158231 0.853801250889739 0.853801250889739 0.398829756175299 0.757753700158231
Nme2 ENSMUSG00000020857 0.213307944885796 0.639923834657388 0.706616781330066 0.706616781330066 0.453225835454266 0.679838753181399
Adprm ENSMUSG00000020910 0.711650020253571 0.711650020253571 0.347639524025037 0.711650020253571 0.711240436189781 0.711650020253571
Nudt13 ENSMUSG00000021809 0.454942951775341 0.682414427663012 0.853801250889739 0.853801250889739 0.0763619660358786 0.229085898107636
Umps ENSMUSG00000022814 0.853480389728993 0.853480389728993 0.0761127945805736 0.114542949053818 0.0763619660358785 0.114542949053818
Tyms ENSMUSG00000025747 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.254787123615605 0.764361370846816
Nudt5 ENSMUSG00000025817 0.45596561163947 0.577829325134931 0.399548817627028 0.577829325134931 0.577829325134931 0.577829325134931
Dtymk ENSMUSG00000026281 0.926550375688041 0.926550375688041 0.710208797518812 0.926550375688041 0.299349060054895 0.898047180164686
Uck2 ENSMUSG00000026558 0.256271555563966 0.768814666691898 0.642366752097095 0.852832278580641 0.852832278580641 0.852832278580641
Dut ENSMUSG00000027203 0.578113371816017 0.712057867818062 0.712057867818062 0.712057867818062 0.711854160331342 0.712057867818062
Cda ENSMUSG00000028755 0.577259514257969 0.577259514257969 0.119631084167592 0.358893252502775 0.399548817627028 0.577259514257969
Paics ENSMUSG00000029247 0.180293335960318 0.322146785907891 0.214764523938594 0.322146785907891 0.511097249598474 0.511097249598474
Nudt1 ENSMUSG00000036639 0.216214347033995 0.382180685423408 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Adk ENSMUSG00000039197 0.78148726569172 0.853801250889739 0.853801250889739 0.853801250889739 0.643359829732651 0.853801250889739
Dnph1 ENSMUSG00000040658 0.0579478375430677 0.173843512629203 0.782117202022501 1 1 1
Gpx1 ENSMUSG00000063856 0.256271555563966 0.384407333345949 0.21549027811633 0.384407333345949 0.578113371816017 0.578113371816017
Itpa ENSMUSG00000074797 0.924639851733043 0.925217182211634 0.0969812105731562 0.290943631719469 0.925217182211634 0.925217182211634
Uckl1 ENSMUSG00000089917 0.255901190956604 0.383851786434906 0.214037080764326 0.383851786434906 0.78180291566155 0.78180291566155

Gap-filling DNA repair synthesis and ligation in GG-NER

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Ube2l6 ENSMUSG00000027078 0.782117202022501 0.782117202022501 0.213307944885796 0.319961917328694 0.180293335960318 0.319961917328694
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Rchy1 ENSMUSG00000029397 0.454942951775341 1 0.711854160331342 1 1 1
Uba7 ENSMUSG00000032596 0.0919695072173338 0.275908521652001 0.711650020253571 0.711650020253571 0.514300775319626 0.711650020253571
Pold1 ENSMUSG00000038644 0.513665062682276 0.770497594023414 0.252920381501206 0.758761144503618 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Interleukin-1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Ager ENSMUSG00000015452 0.578113371816017 0.641867098978198 0.641867098978198 0.641867098978198 0.514300775319626 0.641867098978198
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Il1r1 ENSMUSG00000026072 0.00974037464901008 0.0292211239470303 0.393724994268831 0.590587491403246 0.711240436189781 0.711240436189781
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Tnip2 ENSMUSG00000059866 0.118714930081337 0.35614479024401 0.456305241393103 0.643359829732651 0.643359829732651 0.643359829732651
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Hmgb1 ENSMUSG00000066551 0.120545895661627 0.180818843492441 0.010906560635693 0.032719681907079 0.295581119060361 0.295581119060361
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Regulation of RUNX3 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfb1 ENSMUSG00000002603 0.0947558980989551 0.284267694296865 0.300095920620218 0.450143880930327 0.643359829732651 0.643359829732651
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Translesion synthesis by POLI

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Degradation of AXIN

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Axin2 ENSMUSG00000000142 0.397384062266614 0.577829325134931 0.577829325134931 0.577829325134931 0.348008842235184 0.577829325134931
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Translesion synthesis by REV1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

SCF(Skp2)-mediated degradation of p27/p21

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Zfp36l1 ENSMUSG00000021127 0.511097249598474 0.57113445032749 0.45596561163947 0.57113445032749 0.57113445032749 0.57113445032749
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Pabpc1 ENSMUSG00000022283 0.214037080764326 0.321055621146488 0.0441715176243983 0.132514552873195 0.643359829732651 0.643359829732651
Exosc7 ENSMUSG00000025785 0.78180291566155 0.853372965654504 0.853372965654504 0.853372965654504 0.578113371816017 0.853372965654504
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Exosc8 ENSMUSG00000027752 1 1 0.926658283600152 1 0.297848640636702 0.893545921910107
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488
Hspa1b ENSMUSG00000090877 0.214037080764326 0.642111242292977 0.852832278580641 0.852832278580641 0.643853282854191 0.852832278580641

Activation of NF-kappaB in B cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

APC-Cdc20 mediated degradation of Nek2A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Anapc16 ENSMUSG00000020107 0.347639524025037 1 0.926441990075769 1 1 1
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Anapc4 ENSMUSG00000029176 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Anapc15 ENSMUSG00000030649 0.926550375688041 0.926550375688041 0.853480389728993 0.926550375688041 0.640861491578951 0.926550375688041
Cdc16 ENSMUSG00000038416 0.781011212316137 0.85326530496423 0.85326530496423 0.85326530496423 0.45596561163947 0.85326530496423
Cdc26 ENSMUSG00000066149 0.299349060054895 0.449023590082343 0.0964252305385472 0.289275691615642 1 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

G1/S Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mcm5 ENSMUSG00000005410 0.452880492349546 0.452880492349546 0.0548979200435556 0.164693760130667 0.146141353215796 0.219212029823693
Gmnn ENSMUSG00000006715 0.926550375688041 0.926550375688041 0.397384062266614 0.596076093399921 0.0583853430099098 0.175156029029729
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Orc2 ENSMUSG00000026037 0.708323672944427 0.853587578053106 0.853587578053106 0.853587578053106 0.119325847749354 0.357977543248062
Orc4 ENSMUSG00000026761 0.0964252305385473 0.270440003940477 0.180293335960318 0.270440003940477 0.638824656785692 0.638824656785692
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Orc5 ENSMUSG00000029012 0.5155648232968 0.853372965654504 0.643359829732651 0.853372965654504 0.853372965654504 0.853372965654504
Cdc7 ENSMUSG00000029283 0.853694531487825 0.853694531487825 0.398829756175299 0.598244634262948 0.347639524025037 0.598244634262948
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Organelle biogenesis and maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B9d1 ENSMUSG00000001039 0.447621891168214 0.67143283675232 0.0766111619812296 0.229833485943689 0.709375484777034 0.709375484777034
Ift20 ENSMUSG00000001105 0.92622377157404 0.92622377157404 0.255901190956604 0.680355804032917 0.453570536021945 0.680355804032917
Cct3 ENSMUSG00000001416 0.346899083932133 0.513026869856283 0.453225835454266 0.513026869856283 0.513026869856283 0.513026869856283
Rab8a ENSMUSG00000003037 0.447265995733381 0.563485358844814 0.255901190956604 0.563485358844814 0.563485358844814 0.563485358844814
Ift43 ENSMUSG00000007867 0.0443599545252852 0.133079863575856 1 1 0.782117202022501 1
Cluap1 ENSMUSG00000014232 1 1 0.852940894477647 1 0.256271555563966 0.768814666691898
Cdk1 ENSMUSG00000019942 0.78180291566155 0.78180291566155 0.256271555563966 0.520348625898199 0.346899083932133 0.520348625898199
Fbf1 ENSMUSG00000020776 0.926003599371282 0.926003599371282 0.023800255149993 0.0714007654499789 0.636229315311352 0.926003599371282
Asap1 ENSMUSG00000022377 1 1 0.78148726569172 1 0.782117202022501 1
Iqcb1 ENSMUSG00000022837 0.853907737111068 0.926550375688041 0.17750354896016 0.53251064688048 0.926550375688041 0.926550375688041
Atp5j ENSMUSG00000022890 0.400265374208515 0.600398061312773 0.399548817627028 0.600398061312773 0.853801250889739 0.853801250889739
Arl13b ENSMUSG00000022911 0.780851835278818 0.780851835278818 0.214764523938594 0.449023590082343 0.299349060054895 0.449023590082343
Sfi1 ENSMUSG00000023764 0.853907737111068 0.853907737111068 0.348008842235184 0.853907737111068 0.78180291566155 0.853907737111068
Tmem216 ENSMUSG00000024667 0.344663224299303 0.642864324224729 0.575824878403157 0.642864324224729 0.642864324224729 0.642864324224729
Gbf1 ENSMUSG00000025224 0.711034989117171 0.711034989117171 0.243396309647536 0.442231101684348 0.294820734456232 0.442231101684348
Sdccag8 ENSMUSG00000026504 0.5155648232968 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Ssna1 ENSMUSG00000026966 0.214764523938594 0.42708569000985 0.2847237933399 0.42708569000985 0.638824656785692 0.638824656785692
Gabpb1 ENSMUSG00000027361 1 1 0.400265374208515 1 0.853372965654504 1
Sirt4 ENSMUSG00000029524 0.21549027811633 0.64647083434899 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769
Mark4 ENSMUSG00000030397 0.397384062266614 0.853480389728993 0.853480389728993 0.853480389728993 0.782117202022501 0.853480389728993
Hdac6 ENSMUSG00000031161 0.573498913947369 0.578113371816017 0.344663224299303 0.578113371816017 0.578113371816017 0.578113371816017
Haus7 ENSMUSG00000031371 0.643359829732651 0.643359829732651 0.342026805366747 0.51304020805012 0.300095920620218 0.51304020805012
Mks1 ENSMUSG00000034121 0.853694531487825 0.853801250889739 0.643359829732651 0.853801250889739 0.853801250889739 0.853801250889739
Atp5h ENSMUSG00000034566 0.78180291566155 0.852504981253341 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341
Ttc21b ENSMUSG00000034848 0.21549027811633 0.64647083434899 0.454600801949285 0.681901202923927 0.9255572759333 0.9255572759333
Bbs10 ENSMUSG00000035759 0.853587578053106 0.853587578053106 0.399189600887034 0.853587578053106 0.643112334413352 0.853587578053106
Exoc1 ENSMUSG00000036435 0.926550375688041 0.926550375688041 0.78180291566155 0.926550375688041 0.142165951159432 0.426497853478296
Atp5j2 ENSMUSG00000038690 0.568427079091759 0.780851835278818 0.255901190956604 0.767703572869811 0.780851835278818 0.780851835278818
Atp5l ENSMUSG00000038717 0.853049270252403 0.926003599371282 0.299349060054895 0.898047180164686 0.926003599371282 0.926003599371282
Cc2d2a ENSMUSG00000039765 0.0325051220296005 0.0882349010820225 0.058823267388015 0.0882349010820225 0.577829325134931 0.577829325134931
Haus1 ENSMUSG00000041840 0.514934023620344 0.78148726569172 0.711034989117171 0.78148726569172 0.78148726569172 0.78148726569172
Atp5k ENSMUSG00000050856 0.216214347033995 0.596076093399921 0.397384062266614 0.596076093399921 0.642366752097095 0.642366752097095
Gm10053 ENSMUSG00000058927 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.509798138101151 0.926550375688041
Tcp1 ENSMUSG00000068039 0.782117202022501 0.782117202022501 0.216214347033995 0.648643041101984 0.78180291566155 0.782117202022501
Fgfr1op ENSMUSG00000069135 0.399548817627028 0.712057867818062 0.712057867818062 0.712057867818062 0.712057867818062 0.712057867818062

Translesion synthesis by POLK

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rfc4 ENSMUSG00000022881 0.642615797383338 0.852832278580641 0.397746436553874 0.852832278580641 0.852832278580641 0.852832278580641
Rfc2 ENSMUSG00000023104 0.708534948098331 0.709375484777034 0.642864324224729 0.709375484777034 0.709375484777034 0.709375484777034
Pcna ENSMUSG00000027342 0.711240436189781 0.711240436189781 0.242620429494012 0.711240436189781 0.641867098978198 0.711240436189781
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Formation of TC-NER Pre-Incision Complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Polr2i ENSMUSG00000019738 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.78180291566155 0.852832278580641
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Polr2d ENSMUSG00000024258 0.252545530864481 0.755733790684098 0.503822527122732 0.755733790684098 1 1
Ppie ENSMUSG00000028651 0.348008842235184 0.780851835278817 0.642366752097095 0.780851835278817 0.780851835278817 0.780851835278817
Ercc2 ENSMUSG00000030400 0.0753654386865988 0.142968849950909 0.0953125666339397 0.142968849950909 0.454942951775342 0.454942951775342
Cul4a ENSMUSG00000031446 0.642366752097095 0.643359829732651 0.452880492349546 0.643359829732651 0.643359829732651 0.643359829732651
Gtf2h5 ENSMUSG00000034345 0.708745765211584 0.708745765211584 0.0763619660358786 0.229085898107636 0.635703516568383 0.708745765211584
Polr2k ENSMUSG00000045996 0.926550375688041 0.926550375688041 0.300095920620218 0.900287761860654 0.926333123228344 0.926550375688041
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Polr2g ENSMUSG00000071662 0.399548817627028 0.600398061312773 0.400265374208515 0.600398061312773 0.711240436189781 0.711240436189781
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Synthesis of dolichyl-phosphate mannose

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dpm2 ENSMUSG00000026810 0.148772260628989 0.446316781886968 0.45596561163947 0.683948417459205 0.78148726569172 0.78148726569172
Dpm3 ENSMUSG00000042737 0.348008842235184 0.522013263352776 0.347639524025037 0.522013263352776 0.926550375688041 0.926550375688041
Gm20716 ENSMUSG00000093752 0.711854160331342 0.711854160331342 0.297848640636702 0.599323226440542 0.399548817627028 0.599323226440542

Degradation of DVL

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

Degradation of beta-catenin by the destruction complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psmb1 ENSMUSG00000014769 0.455965611639469 0.683948417459204 0.300095920620218 0.683948417459204 0.851061028660105 0.851061028660105
Psmb6 ENSMUSG00000018286 0.782117202022501 0.853801250889739 0.578113371816017 0.853801250889739 0.853801250889739 0.853801250889739
Rps27a ENSMUSG00000020460 0.451840588205062 0.642864324224729 0.453225835454266 0.642864324224729 0.642864324224729 0.642864324224729
Psmd6 ENSMUSG00000021737 0.711240436189781 1 0.577259514257969 1 1 1
Rbx1 ENSMUSG00000022400 0.78148726569172 0.78148726569172 0.643359829732651 0.78148726569172 0.643359829732651 0.78148726569172
Psmd14 ENSMUSG00000026914 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641 0.575536202757516 0.852832278580641
Psma7 ENSMUSG00000027566 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.78148726569172 0.853694531487825
Lef1 ENSMUSG00000027985 0.711034989117171 0.711034989117171 0.347639524025037 0.683438032073173 0.455625354715448 0.683438032073173
Cul1 ENSMUSG00000029686 0.780851835278818 0.780851835278818 0.347639524025037 0.521459286037555 0.347639524025037 0.521459286037555
Psmd10 ENSMUSG00000031429 0.346527959006435 0.519791938509652 0.121155015244363 0.36346504573309 0.853372965654504 0.853372965654504
Skp1a ENSMUSG00000036309 0.708745765211584 0.708745765211584 0.214037080764326 0.642111242292977 0.575824878403157 0.708745765211584
Psma3 ENSMUSG00000060073 1 1 0.514934023620345 1 0.7802108304765 1
Gm11808 ENSMUSG00000068240 0.297848640636702 0.771451162979439 0.514300775319626 0.771451162979439 1 1
Psmb3 ENSMUSG00000069744 0.852940894477647 0.926333123228344 0.577829325134931 0.926333123228344 0.926333123228344 0.926333123228344
Psme2 ENSMUSG00000079197 0.513026869856283 0.513026869856283 0.508488713161374 0.513026869856283 0.338976281569376 0.513026869856283
Uba52 ENSMUSG00000090137 0.146800541856249 0.321055621146488 0.926658283600152 0.926658283600152 0.214037080764326 0.321055621146488

blanchedalmond

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.711034989117171 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Raf1 ENSMUSG00000000441 0.926441990075769 0.926441990075769 0.513665062682276 0.926441990075769 0.853372965654504 0.926441990075769
Tcf7 ENSMUSG00000000782 0.399548817627028 0.599323226440542 0.255901190956604 0.599323226440542 0.78180291566155 0.78180291566155
Calm1 ENSMUSG00000001175 0.643853282854191 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Smo ENSMUSG00000001761 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155 0.348008842235184 0.78180291566155
Ccne1 ENSMUSG00000002068 0.513665062682276 0.770497594023414 0.853372965654504 0.853372965654504 0.0331400397096515 0.0994201191289545
Stat5a ENSMUSG00000004043 0.924872384323464 0.924872384323464 0.11810342389482 0.354310271684459 0.45596561163947 0.683948417459205
Bid ENSMUSG00000004446 0.0936419271039908 0.280925781311972 0.576112968612194 0.704220158648919 0.704220158648919 0.704220158648919
Ralb ENSMUSG00000004451 0.395928178642446 0.497625221907634 0.0964252305385471 0.289275691615641 0.497625221907634 0.497625221907634
Msh6 ENSMUSG00000005370 0.148115998140415 0.370292939183197 0.246861959455465 0.370292939183197 0.643359829732651 0.643359829732651
Runx1t1 ENSMUSG00000006586 0.0964252305385471 0.289275691615641 0.926550375688041 0.926658283600152 0.926658283600152 0.926658283600152
Cdk4 ENSMUSG00000006728 0.926550375688041 0.926550375688041 0.711034989117171 0.926550375688041 0.853801250889739 0.926550375688041
Ctnnb1 ENSMUSG00000006932 0.295581119060361 0.63250023504486 0.63250023504486 0.63250023504486 0.63086665720673 0.63250023504486
Rassf1 ENSMUSG00000010067 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041 0.711854160331342 0.926550375688041
Dll1 ENSMUSG00000014773 0.643853282854191 0.643853282854191 0.11993617140438 0.359808514213139 0.642366752097095 0.643853282854191
Itga2 ENSMUSG00000015533 0.295581119060361 0.443371678590541 0.29558111906036 0.443371678590541 0.450444934184774 0.450444934184774
Nfe2l2 ENSMUSG00000015839 0.643853282854191 0.926550375688041 0.78180291566155 0.926550375688041 0.926550375688041 0.926550375688041
Il13ra1 ENSMUSG00000017057 0.513026869856283 0.863737317604735 1 1 0.575824878403157 0.863737317604735
Traf4 ENSMUSG00000017386 0.395928178642446 1 1 1 0.782117202022501 1
Mmp9 ENSMUSG00000017737 0.0756145297453646 0.226843589236094 0.926550375688041 0.926550375688041 0.399548817627028 0.599323226440542
Il12rb2 ENSMUSG00000018341 0.0728763274684321 0.126222381716745 0.0841482544778298 0.126222381716745 0.567818482366294 0.567818482366294
Hey2 ENSMUSG00000019789 0.254414773803597 0.381622160705395 0.148115998140415 0.381622160705395 0.925444427431699 0.925444427431699
Lama4 ENSMUSG00000019846 0.926333123228344 0.926333123228344 0.711854160331342 0.926333123228344 0.348008842235184 0.926333123228344
Apaf1 ENSMUSG00000019979 0.926550375688041 0.926550375688041 0.254414773803597 0.763244321410791 0.711854160331342 0.926550375688041
Ifngr1 ENSMUSG00000020009 0.454942951775341 0.682414427663012 0.453570536021945 0.682414427663012 0.853801250889739 0.853801250889739
Gna13 ENSMUSG00000020611 0.642366752097095 0.853694531487825 0.853049270252403 0.853694531487825 0.853694531487825 0.853694531487825
Stat5b ENSMUSG00000020919 0.398108175780842 0.599323226440542 0.638824656785692 0.638824656785692 0.399548817627028 0.599323226440542
Hif1a ENSMUSG00000021109 0.11595859961889 0.178072395122005 0.118714930081337 0.178072395122005 0.643853282854191 0.643853282854191
Ptch1 ENSMUSG00000021466 0.252545530864481 0.576973746230334 0.576973746230334 0.576973746230334 0.45596561163947 0.576973746230334
Bmp4 ENSMUSG00000021835 0.455625354715448 0.683438032073173 0.148115998140416 0.444347994421247 0.779888212132595 0.779888212132595
Wnt5a ENSMUSG00000021994 0.345037391052887 0.517556086579331 0.298599969973533 0.517556086579331 0.576973746230334 0.576973746230334
Fgf17 ENSMUSG00000022101 0.853801250889739 0.853801250889739 0.250285839267991 0.37938057225181 0.252920381501207 0.37938057225181
Ednrb ENSMUSG00000022122 0.5155648232968 0.711854160331342 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342
Runx1 ENSMUSG00000022952 0.000143939694472871 0.000431819083418612 0.0756145297453646 0.113421794618047 0.514300775319626 0.514300775319626
Ifnar2 ENSMUSG00000022971 0.146800541856249 0.440401625568746 1 1 0.711034989117171 1
Wnt10b ENSMUSG00000022996 0.454600801949285 0.513665062682276 0.014844565205092 0.0445336956152759 0.513665062682276 0.513665062682276
Gnb3 ENSMUSG00000023439 0.710622777116399 0.853157406788312 0.853157406788312 0.853157406788312 0.345410946355105 0.853157406788312
Pim1 ENSMUSG00000024014 0.711650020253571 0.782117202022501 0.782117202022501 0.782117202022501 0.78180291566155 0.782117202022501
Lama3 ENSMUSG00000024421 0.294820734456232 0.442231101684348 0.0592616003460512 0.177784801038154 0.926658283600152 0.926658283600152
Sufu ENSMUSG00000025231 0.348008842235184 0.641867098978198 0.451840588205062 0.641867098978198 0.641867098978198 0.641867098978198
Cdk2 ENSMUSG00000025358 0.781011212316137 0.781011212316137 0.346527959006435 0.781011212316137 0.643112334413352 0.781011212316137
Stat1 ENSMUSG00000026104 0.297848640636702 0.599323226440542 0.399548817627028 0.599323226440542 0.638310022345193 0.638310022345193
Lamc1 ENSMUSG00000026478 0.21549027811633 0.64647083434899 0.78148726569172 0.78148726569172 0.455625354715449 0.683438032073173
Traf1 ENSMUSG00000026875 0.782117202022501 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Itgav ENSMUSG00000027087 0.853480389728993 0.853480389728993 0.0162664168407233 0.04879925052217 0.120545895661628 0.180818843492441
Itga6 ENSMUSG00000027111 0.850721744111585 0.850721744111585 0.0241933715424143 0.0725801146272428 0.576112968612194 0.850721744111585
Traf6 ENSMUSG00000027164 0.711240436189781 0.926333123228344 0.513026869856283 0.926333123228344 0.926333123228344 0.926333123228344
Jag1 ENSMUSG00000027276 0.254414773803597 0.381622160705395 0.0964252305385472 0.289275691615642 0.710416009055326 0.710416009055326
Pld1 ENSMUSG00000027695 0.640861491578951 0.851061028660105 0.0756145297453648 0.226843589236094 0.851061028660105 0.851061028660105
Il12a ENSMUSG00000027776 0.576112968612194 0.853372965654504 0.853372965654504 0.853372965654504 0.45596561163947 0.853372965654504
Ccna1 ENSMUSG00000027793 0.252170177483002 0.287481513930451 0.209267277690899 0.287481513930451 0.287481513930451 0.287481513930451
Notch2 ENSMUSG00000027878 0.395928178642446 0.593892267963669 0.0733738589968006 0.220121576990402 0.924872384323463 0.924872384323463
Gstm4 ENSMUSG00000027890 0.400265374208515 0.600398061312773 0.024062085667391 0.072186257002173 0.711650020253571 0.711650020253571
Egf ENSMUSG00000028017 0.577259514257969 0.7802108304765 0.254787123615605 0.764361370846816 0.7802108304765 0.7802108304765
Cks1b ENSMUSG00000028044 0.926658283600152 0.926658283600152 0.179945789077372 0.269918683616058 0.179945789077372 0.269918683616058
Ntrk1 ENSMUSG00000028072 0.92622377157404 0.926333123228344 0.395196379647461 0.926333123228344 0.926333123228344 0.926333123228344
Nfkb1 ENSMUSG00000028163 0.710208797518812 0.853801250889739 0.853801250889739 0.853801250889739 0.298599969973533 0.853801250889739
Ptch2 ENSMUSG00000028681 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342 0.453225835454266 0.711854160331342
Hdac1 ENSMUSG00000028800 0.853480389728993 0.853480389728993 0.0964252305385471 0.289275691615641 0.78180291566155 0.853480389728993
Wnt16 ENSMUSG00000029671 0.514300775319626 0.853049270252403 0.853049270252403 0.853049270252403 0.711650020253571 0.853049270252403
Tgfa ENSMUSG00000029999 0.399548817627028 0.643359829732651 0.643359829732651 0.643359829732651 0.455965611639471 0.643359829732651
Wnt7a ENSMUSG00000030093 0.711240436189781 0.7802108304765 0.173632433887832 0.520897301663497 0.7802108304765 0.7802108304765
Ret ENSMUSG00000030110 0.345037391052887 0.517556086579331 0.780692109850228 0.780692109850228 0.294439684556453 0.517556086579331
Fgfr2 ENSMUSG00000030849 0.455625354715449 0.683438032073173 0.144820068500793 0.43446020550238 1 1
Ctbp2 ENSMUSG00000030970 0.044926265292481 0.134778795877443 0.214037080764326 0.255530331334266 0.255530331334266 0.255530331334266
Fgf16 ENSMUSG00000031230 0.851954599472143 0.851954599472143 0.174692232033629 0.524076696100887 0.776919261684345 0.851954599472143
Col4a2 ENSMUSG00000031503 0.779888212132595 0.779888212132595 0.643359829732651 0.779888212132595 0.706616781330066 0.779888212132595
Fgfr1 ENSMUSG00000031565 0.398108175780842 0.398108175780842 0.142830916318171 0.398108175780842 0.346527959006435 0.398108175780842
Casp3 ENSMUSG00000031628 0.398108175780842 0.597162263671263 0.0432318933800775 0.129695680140233 0.642366752097095 0.642366752097095
Agt ENSMUSG00000031980 0.642366752097095 0.643359829732651 0.577259514257969 0.643359829732651 0.643359829732651 0.643359829732651
Gsta4 ENSMUSG00000032348 0.640355507848752 0.853801250889739 0.853801250889739 0.853801250889739 0.0579478375430677 0.173843512629203
Dapk2 ENSMUSG00000032380 0.926333123228344 1 0.78180291566155 1 1 1
Ptgs2 ENSMUSG00000032487 0.578113371816017 0.78180291566155 0.711854160331342 0.78180291566155 0.78180291566155 0.78180291566155
Heyl ENSMUSG00000032744 0.780851835278818 0.926333123228344 0.214037080764326 0.642111242292978 0.926333123228344 0.926333123228344
Wnt6 ENSMUSG00000033227 0.711240436189781 0.853372965654504 0.455625354715448 0.853372965654504 0.853372965654504 0.853372965654504
Mitf ENSMUSG00000035158 0.455625354715449 0.683438032073173 0.148772260628989 0.446316781886968 0.782117202022501 0.782117202022501
Calm2 ENSMUSG00000036438 0.299349060054895 0.45596561163947 0.45596561163947 0.45596561163947 0.400265374208515 0.45596561163947
Lpar3 ENSMUSG00000036832 0.709793037667153 0.710001140920767 0.0577292451600846 0.173187735480254 0.710001140920767 0.710001140920767
Lpar1 ENSMUSG00000038668 0.214037080764326 0.321055621146488 0.0743693776059065 0.223108132817719 0.926550375688041 0.926550375688041
Plekhg5 ENSMUSG00000039713 0.926441990075769 0.926441990075769 0.78180291566155 0.926441990075769 0.514934023620345 0.926441990075769
Plcb2 ENSMUSG00000040061 0.853801250889739 0.926658283600152 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152
Gstm2 ENSMUSG00000040562 0.782117202022501 0.853907737111068 0.853907737111068 0.853907737111068 0.455625354715449 0.853907737111068
Arhgef1 ENSMUSG00000040940 0.642864324224729 0.711650020253571 0.147458757705094 0.442376273115283 0.711650020253571 0.711650020253571
Brca2 ENSMUSG00000041147 0.511742979522636 0.640861491578951 0.0104326641569827 0.0312979924709482 0.640861491578951 0.640861491578951
Foxo1 ENSMUSG00000044167 0.456305241393103 0.926658283600152 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Fzd5 ENSMUSG00000045005 0.853801250889739 0.853801250889739 0.455625354715449 0.853801250889739 0.711445446052875 0.853801250889739
Cxcr4 ENSMUSG00000045382 0.399548817627028 0.961292237368426 0.640861491578951 0.961292237368426 1 1
Hes5 ENSMUSG00000048001 0.456305241393103 0.456305241393103 0.454600801949285 0.456305241393103 0.398108175780842 0.456305241393103
F2r ENSMUSG00000048376 0.17750354896016 0.446772960955053 1 1 0.297848640636702 0.446772960955053
Kif7 ENSMUSG00000050382 0.853157406788312 0.853157406788312 0.0588232673880149 0.176469802164045 0.853157406788312 0.853157406788312
Prkcb ENSMUSG00000052889 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517 0.782117202022501 0.782117202022501
Alk ENSMUSG00000055471 0.637013771824329 0.849224249283192 0.849224249283192 0.849224249283192 0.780049698709835 0.849224249283192
Camk2b ENSMUSG00000057897 0.452880492349546 0.514934023620345 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Gng8 ENSMUSG00000063594 0.711240436189781 0.711240436189781 0.640861491578951 0.711240436189781 0.346527959006435 0.711240436189781
Gstm6 ENSMUSG00000068762 0.299349060054895 0.853801250889739 0.78148726569172 0.853801250889739 0.853801250889739 0.853801250889739

Wnt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.711034989117171 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Serpinf1 ENSMUSG00000000753 0.7802108304765 0.782117202022501 0.214037080764326 0.642111242292977 0.782117202022501 0.782117202022501
Tcf7 ENSMUSG00000000782 0.399548817627028 0.599323226440542 0.255901190956604 0.599323226440542 0.78180291566155 0.78180291566155
Ctnnb1 ENSMUSG00000006932 0.295581119060361 0.63250023504486 0.63250023504486 0.63250023504486 0.63086665720673 0.63250023504486
Sfrp5 ENSMUSG00000018822 0.45149265530335 0.766160146926689 0.926496242814507 0.926496242814507 0.51077343128446 0.766160146926689
Rspo3 ENSMUSG00000019880 0.120545895661628 0.180818843492441 0.0451153644990945 0.135346093497283 0.711240436189781 0.711240436189781
Lgr5 ENSMUSG00000020140 0.395928178642446 0.593892267963669 0.120545895661627 0.361637686984882 1 1
Wif1 ENSMUSG00000020218 0.706616781330066 0.706616781330066 0.178901132102685 0.536703396308054 0.573791743469336 0.706616781330066
Sfrp4 ENSMUSG00000021319 0.511742979522636 0.511742979522636 0.290984282074805 0.436476423112208 0.146800541856249 0.436476423112208
Nkd2 ENSMUSG00000021567 0.119631084167592 0.179446626251387 0.11595859961889 0.179446626251387 0.642366752097095 0.642366752097095
Wnt5a ENSMUSG00000021994 0.345037391052887 0.517556086579331 0.298599969973533 0.517556086579331 0.576973746230334 0.576973746230334
Senp2 ENSMUSG00000022855 0.211110344399808 0.633331033199424 0.456305241393103 0.642366752097095 0.642366752097095 0.642366752097095
Wnt10b ENSMUSG00000022996 0.454600801949285 0.513665062682276 0.014844565205092 0.0445336956152759 0.513665062682276 0.513665062682276
Bambi ENSMUSG00000024232 0.214037080764326 0.321055621146489 0.214037080764326 0.321055621146489 0.513026869856283 0.513026869856283
Tbl1x ENSMUSG00000025246 0.710208797518812 1 1 1 0.455625354715449 1
Sfrp2 ENSMUSG00000027996 0.17610058307789 0.528301749233671 0.392985378348026 0.589478067522039 0.643359829732651 0.643359829732651
Dkk2 ENSMUSG00000028031 0.577829325134931 0.866743987702397 0.0328221470541517 0.098466441162455 0.925217182211634 0.925217182211634
Rspo1 ENSMUSG00000028871 0.852175490580835 0.852175490580835 0.511097249598474 0.766645874397711 0.214037080764326 0.642111242292977
Wnt16 ENSMUSG00000029671 0.514300775319626 0.853049270252403 0.853049270252403 0.853049270252403 0.711650020253571 0.853049270252403
Wnt7a ENSMUSG00000030093 0.711240436189781 0.7802108304765 0.173632433887832 0.520897301663497 0.7802108304765 0.7802108304765
Ctbp2 ENSMUSG00000030970 0.044926265292481 0.134778795877443 0.214037080764326 0.255530331334266 0.255530331334266 0.255530331334266
Prickle3 ENSMUSG00000031145 0.5155648232968 0.7733472349452 0.92622377157404 0.92622377157404 0.299349060054895 0.7733472349452
Nfatc3 ENSMUSG00000031902 0.926604389137101 0.926604389137101 0.514617706526787 0.926604389137101 0.71082910328023 0.926604389137101
Ryk ENSMUSG00000032547 0.347639524025037 0.521459286037555 0.0763619660358786 0.229085898107636 0.710416009055326 0.710416009055326
Wnt6 ENSMUSG00000033227 0.711240436189781 0.853372965654504 0.455625354715448 0.853372965654504 0.853372965654504 0.853372965654504
Ppp3r1 ENSMUSG00000033953 0.853801250889739 0.853801250889739 0.348377561241889 0.853801250889739 0.712057867818062 0.853801250889739
Tle6 ENSMUSG00000034758 0.711854160331342 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Plcb2 ENSMUSG00000040061 0.853801250889739 0.926658283600152 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152
Lgr6 ENSMUSG00000042793 0.298599969973533 0.447899954960299 0.0115535350288052 0.0346606050864156 0.9255572759333 0.9255572759333
Fzd5 ENSMUSG00000045005 0.853801250889739 0.853801250889739 0.455625354715449 0.853801250889739 0.711445446052875 0.853801250889739
Lgr4 ENSMUSG00000050199 0.712057867818062 0.926441990075769 0.397384062266614 0.926441990075769 0.926441990075769 0.926441990075769
Prkcb ENSMUSG00000052889 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517 0.782117202022501 0.782117202022501
Chd8 ENSMUSG00000053754 0.216214347033995 0.324321520550992 0.179945789077372 0.324321520550992 0.776919261684345 0.776919261684345
Camk2b ENSMUSG00000057897 0.452880492349546 0.514934023620345 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Csnk2a1 ENSMUSG00000074698 0.11595859961889 0.173937899428335 0.0763619660358787 0.173937899428335 0.92589277149125 0.92589277149125
Prickle4 ENSMUSG00000096549 0.641616487517698 0.641616487517698 0.00151453507627585 0.00454360522882756 0.044926265292481 0.0673893979387216

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Raf1 ENSMUSG00000000441 0.926441990075769 0.926441990075769 0.513665062682276 0.926441990075769 0.853372965654504 0.926441990075769
Smo ENSMUSG00000001761 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155 0.348008842235184 0.78180291566155
Efnb3 ENSMUSG00000003934 0.7802108304765 1 1 1 0.711854160331342 1
Ephb3 ENSMUSG00000005958 0.514300775319626 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Ntn4 ENSMUSG00000020019 0.454600801949285 0.681901202923927 0.147458757705094 0.442376273115283 0.711240436189781 0.711240436189781
Srgap1 ENSMUSG00000020121 0.926658283600152 1 1 1 1 1
Ntn1 ENSMUSG00000020902 0.781170242226513 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Ptch1 ENSMUSG00000021466 0.252545530864481 0.576973746230334 0.576973746230334 0.576973746230334 0.45596561163947 0.576973746230334
Wnt5a ENSMUSG00000021994 0.345037391052887 0.517556086579331 0.298599969973533 0.517556086579331 0.576973746230334 0.576973746230334
Myl12a ENSMUSG00000024048 0.926333123228344 0.926333123228344 0.347639524025037 0.600398061312773 0.400265374208515 0.600398061312773
Sema4g ENSMUSG00000025207 0.514934023620345 0.772401035430517 1 1 0.513665062682276 0.772401035430517
Pard3 ENSMUSG00000025812 0.853801250889739 0.92589277149125 0.639337105615665 0.92589277149125 0.92589277149125 0.92589277149125
Sema6d ENSMUSG00000027200 0.399548817627028 0.853907737111068 0.853907737111068 0.853907737111068 0.711854160331342 0.853907737111068
Trpc4 ENSMUSG00000027748 0.120850531362929 0.268351698154027 0.578113371816017 0.578113371816017 0.178901132102685 0.268351698154027
Sema4a ENSMUSG00000028064 0.578113371816017 0.7802108304765 0.7802108304765 0.7802108304765 0.711854160331342 0.7802108304765
Epha7 ENSMUSG00000028289 0.254414773803597 0.381622160705395 0.17924968721805 0.381622160705395 0.853694531487825 0.853694531487825
Dpysl5 ENSMUSG00000029168 0.399548817627028 1 0.777922216623952 1 1 1
Epha5 ENSMUSG00000029245 0.146141353215796 0.438424059647387 0.638310022345193 0.638310022345193 0.575536202757516 0.638310022345193
Ephb6 ENSMUSG00000029869 0.710001140920767 0.710001140920767 0.254787123615606 0.519791938509652 0.346527959006435 0.519791938509652
Plxna3 ENSMUSG00000031398 0.0936419271039908 0.144637845807821 0.0964252305385472 0.144637845807821 0.345410946355104 0.345410946355104
Nfatc3 ENSMUSG00000031902 0.926604389137101 0.926604389137101 0.514617706526787 0.926604389137101 0.71082910328023 0.926604389137101
Trpc6 ENSMUSG00000031997 0.853694531487825 0.853694531487825 0.641616487517698 0.853694531487825 0.781011212316137 0.853694531487825
Robo3 ENSMUSG00000032128 0.711650020253571 0.782117202022501 0.711854160331342 0.782117202022501 0.782117202022501 0.782117202022501
Ryk ENSMUSG00000032547 0.347639524025037 0.521459286037555 0.0763619660358786 0.229085898107636 0.710416009055326 0.710416009055326
Ablim3 ENSMUSG00000032735 0.180293335960318 0.270440003940477 0.148115998140415 0.270440003940477 0.708323672944427 0.708323672944427
Ppp3r1 ENSMUSG00000033953 0.853801250889739 0.853801250889739 0.348377561241889 0.853801250889739 0.712057867818062 0.853801250889739
Sema6c ENSMUSG00000038777 0.214764523938594 0.322146785907891 0.0217422311863571 0.0652266935590713 0.395196379647461 0.395196379647461
Pak7 ENSMUSG00000039913 0.297848640636702 0.642366752097095 0.642366752097095 0.642366752097095 0.575536202757516 0.642366752097095
Cxcr4 ENSMUSG00000045382 0.399548817627028 0.961292237368426 0.640861491578951 0.961292237368426 1 1
Lrrc4c ENSMUSG00000050587 0.711034989117171 0.711034989117171 0.398108175780842 0.711034989117171 0.643853282854191 0.711034989117171
Bmpr1b ENSMUSG00000052430 0.643359829732651 0.926003599371282 0.514934023620345 0.926003599371282 0.926003599371282 0.926003599371282
Epha3 ENSMUSG00000052504 0.297848640636702 0.395928178642446 0.395928178642446 0.395928178642446 0.346527959006435 0.395928178642446
Pard6g ENSMUSG00000056214 0.711854160331342 0.926550375688041 0.926550375688041 0.926550375688041 0.454942951775341 0.926550375688041
Camk2b ENSMUSG00000057897 0.452880492349546 0.514934023620345 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Rgs3 ENSMUSG00000059810 0.853372965654504 0.92589277149125 0.348008842235184 0.92589277149125 0.92589277149125 0.92589277149125
Ntng1 ENSMUSG00000059857 0.643359829732651 0.711854160331342 0.710208797518812 0.711854160331342 0.711854160331342 0.711854160331342
Sema3e ENSMUSG00000063531 0.299349060054895 0.449023590082343 0.0761127945805735 0.228338383741721 0.640861491578951 0.640861491578951

Calcium signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Calm1 ENSMUSG00000001175 0.643853282854191 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Grin2d ENSMUSG00000002771 0.0930846407079409 0.279253922123823 0.853480389728993 0.853480389728993 0.643359829732651 0.853480389728993
Pde1c ENSMUSG00000004347 0.782117202022501 1 0.45596561163947 1 1 1
Mcu ENSMUSG00000009647 0.348008842235184 0.639337105615665 0.444394285043028 0.639337105615665 0.639337105615665 0.639337105615665
Plcd1 ENSMUSG00000010660 0.17924968721805 0.537749061654149 0.45596561163947 0.578396848531894 0.578396848531894 0.578396848531894
Cacna1d ENSMUSG00000015968 0.399548817627028 0.399548817627028 0.0384205930139141 0.115261779041742 0.397384062266614 0.399548817627028
Erbb3 ENSMUSG00000018166 0.178901132102685 0.268351698154027 0.144157978128026 0.268351698154027 0.643359829732651 0.643359829732651
Trdn ENSMUSG00000019787 0.454600801949285 0.454600801949285 0.058823267388015 0.176469802164045 0.454600801949285 0.454600801949285
Ppif ENSMUSG00000021868 0.453225835454266 0.863304304136274 0.575536202757516 0.863304304136274 1 1
Fgf17 ENSMUSG00000022101 0.853801250889739 0.853801250889739 0.250285839267991 0.37938057225181 0.252920381501207 0.37938057225181
Ednrb ENSMUSG00000022122 0.5155648232968 0.711854160331342 0.643359829732651 0.711854160331342 0.711854160331342 0.711854160331342
Gdnf ENSMUSG00000022144 0.642117186565222 0.710001140920767 0.710001140920767 0.710001140920767 0.514617706526787 0.710001140920767
Plce1 ENSMUSG00000024998 0.5155648232968 0.7733472349452 0.455625354715449 0.7733472349452 0.853907737111068 0.853907737111068
Plcd4 ENSMUSG00000026173 0.253294730253594 0.521459286037555 0.853801250889739 0.853801250889739 0.347639524025037 0.521459286037555
Ngf ENSMUSG00000027859 0.926333123228344 0.926333123228344 0.295581119060361 0.863304304136274 0.575536202757516 0.863304304136274
Egf ENSMUSG00000028017 0.577259514257969 0.7802108304765 0.254787123615605 0.764361370846816 0.7802108304765 0.7802108304765
Pdgfc ENSMUSG00000028019 0.392985378348026 0.589478067522039 0.144820068500793 0.43446020550238 0.636229315311352 0.636229315311352
Ntrk1 ENSMUSG00000028072 0.92622377157404 0.926333123228344 0.395196379647461 0.926333123228344 0.926333123228344 0.926333123228344
Tacr3 ENSMUSG00000028172 0.509798138101151 0.764697207151727 0.509798138101151 0.764697207151727 0.78180291566155 0.78180291566155
Asph ENSMUSG00000028207 0.781170242226513 0.781170242226513 0.144157978128026 0.432473934384077 0.45596561163947 0.683948417459205
Nos1 ENSMUSG00000029361 0.293293089483362 0.879879268450085 1 1 0.781170242226513 1
P2rx4 ENSMUSG00000029470 0.513665062682276 0.513665062682276 0.148772260628989 0.446316781886968 0.456305241393103 0.513665062682276
Tacr1 ENSMUSG00000030043 0.712057867818062 0.853907737111068 0.782117202022501 0.853907737111068 0.853907737111068 0.853907737111068
Ret ENSMUSG00000030110 0.345037391052887 0.517556086579331 0.780692109850228 0.780692109850228 0.294439684556453 0.517556086579331
Fgfr2 ENSMUSG00000030849 0.455625354715449 0.683438032073173 0.144820068500793 0.43446020550238 1 1
Fgf16 ENSMUSG00000031230 0.851954599472143 0.851954599472143 0.174692232033629 0.524076696100887 0.776919261684345 0.851954599472143
Fgfr1 ENSMUSG00000031565 0.398108175780842 0.398108175780842 0.142830916318171 0.398108175780842 0.346527959006435 0.398108175780842
Mylk3 ENSMUSG00000031698 0.926333123228344 0.926333123228344 0.78148726569172 0.926333123228344 0.399548817627028 0.926333123228344
Pdgfd ENSMUSG00000032006 0.254414773803597 0.578113371816017 0.578113371816017 0.578113371816017 0.577829325134931 0.578113371816017
Ppp3r1 ENSMUSG00000033953 0.853801250889739 0.853801250889739 0.348377561241889 0.853801250889739 0.712057867818062 0.853801250889739
Cacna1a ENSMUSG00000034656 1 1 0.711650020253571 1 0.780851835278817 1
Calm2 ENSMUSG00000036438 0.299349060054895 0.45596561163947 0.45596561163947 0.45596561163947 0.400265374208515 0.45596561163947
Camk4 ENSMUSG00000038128 0.577259514257969 0.642366752097095 0.642366752097095 0.642366752097095 0.252545530864481 0.642366752097095
Plcb2 ENSMUSG00000040061 0.853801250889739 0.926658283600152 0.399548817627028 0.926658283600152 0.926658283600152 0.926658283600152
Ltb4r2 ENSMUSG00000040432 0.502464977245519 0.635703516568382 0.440742051780531 0.635703516568382 0.635703516568382 0.635703516568382
Cxcr4 ENSMUSG00000045382 0.399548817627028 0.961292237368426 0.640861491578951 0.961292237368426 1 1
F2r ENSMUSG00000048376 0.17750354896016 0.446772960955053 1 1 0.297848640636702 0.446772960955053
Oxtr ENSMUSG00000049112 0.148115998140416 0.444347994421247 0.348008842235184 0.522013263352776 0.711650020253571 0.711650020253571
Cacna1c ENSMUSG00000051331 0.397384062266614 0.596076093399921 0.0106683870753909 0.0320051612261727 0.635703516568382 0.635703516568382
Prkcb ENSMUSG00000052889 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517 0.782117202022501 0.782117202022501
Camk2b ENSMUSG00000057897 0.452880492349546 0.514934023620345 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Sphk1 ENSMUSG00000061878 0.640861491578951 0.926441990075769 0.573498913947369 0.926441990075769 0.926441990075769 0.926441990075769
Slc8a3 ENSMUSG00000079055 0.926658283600152 0.926658283600152 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152
Tnnc1 ENSMUSG00000091898 0.926550375688041 0.926550375688041 0.348008842235184 0.926550375688041 0.7802108304765 0.926550375688041

Hippo signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.711034989117171 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Tcf7 ENSMUSG00000000782 0.399548817627028 0.599323226440542 0.255901190956604 0.599323226440542 0.78180291566155 0.78180291566155
Ppp1cc ENSMUSG00000004455 1 1 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Ctnnb1 ENSMUSG00000006932 0.295581119060361 0.63250023504486 0.63250023504486 0.63250023504486 0.63086665720673 0.63250023504486
Rassf1 ENSMUSG00000010067 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041 0.711854160331342 0.926550375688041
Ctgf ENSMUSG00000019997 0.852940894477647 0.852940894477647 0.214037080764326 0.642111242292977 0.710416009055326 0.852940894477647
Llgl1 ENSMUSG00000020536 0.0964252305385472 0.270960820366546 0.180640546911031 0.270960820366546 0.514300775319626 0.514300775319626
Nkd2 ENSMUSG00000021567 0.119631084167592 0.179446626251387 0.11595859961889 0.179446626251387 0.642366752097095 0.642366752097095
Dlg5 ENSMUSG00000021782 0.347639524025037 0.764697207151727 0.509798138101151 0.764697207151727 1 1
Bmp4 ENSMUSG00000021835 0.455625354715448 0.683438032073173 0.148115998140416 0.444347994421247 0.779888212132595 0.779888212132595
Wnt5a ENSMUSG00000021994 0.345037391052887 0.517556086579331 0.298599969973533 0.517556086579331 0.576973746230334 0.576973746230334
Wnt10b ENSMUSG00000022996 0.454600801949285 0.513665062682276 0.014844565205092 0.0445336956152759 0.513665062682276 0.513665062682276
Ppp2r2b ENSMUSG00000024500 0.148772260628989 0.446316781886968 1 1 0.643853282854191 0.965779924281287
Pard3 ENSMUSG00000025812 0.853801250889739 0.92589277149125 0.639337105615665 0.92589277149125 0.92589277149125 0.92589277149125
Trp53bp2 ENSMUSG00000026510 0.925669613555092 0.925669613555092 0.0331400397096515 0.0994201191289544 0.782117202022501 0.925669613555092
Wnt16 ENSMUSG00000029671 0.514300775319626 0.853049270252403 0.853049270252403 0.853049270252403 0.711650020253571 0.853049270252403
Wnt7a ENSMUSG00000030093 0.711240436189781 0.7802108304765 0.173632433887832 0.520897301663497 0.7802108304765 0.7802108304765
Bmp5 ENSMUSG00000032179 0.574375606171923 0.781645261743309 0.00477055016690542 0.0143116505007162 0.781645261743309 0.781645261743309
Bmp8a ENSMUSG00000032726 0.51077343128446 0.51206489523939 0.51077343128446 0.51206489523939 0.51206489523939 0.51206489523939
Wnt6 ENSMUSG00000033227 0.711240436189781 0.853372965654504 0.455625354715448 0.853372965654504 0.853372965654504 0.853372965654504
Amh ENSMUSG00000035262 0.643853282854191 0.643853282854191 0.454600801949285 0.643853282854191 0.300095920620218 0.643853282854191
Crb2 ENSMUSG00000035403 0.782117202022501 0.782117202022501 0.455965611639471 0.782117202022501 0.576112968612194 0.782117202022501
Serpine1 ENSMUSG00000037411 0.17924968721805 0.537749061654149 0.643853282854191 0.711650020253571 0.711650020253571 0.711650020253571
Amot ENSMUSG00000041688 0.711854160331342 0.92622377157404 0.710416009055326 0.92622377157404 0.92622377157404 0.92622377157404
Ppp2r2d ENSMUSG00000041769 0.0171027900598199 0.0513083701794597 0.578113371816017 0.867170057724026 1 1
Fzd5 ENSMUSG00000045005 0.853801250889739 0.853801250889739 0.455625354715449 0.853801250889739 0.711445446052875 0.853801250889739
Gdf6 ENSMUSG00000051279 0.396293111123657 0.594439666685485 0.295960456252635 0.594439666685485 0.925160045487646 0.925160045487646
Bmpr1b ENSMUSG00000052430 0.643359829732651 0.926003599371282 0.514934023620345 0.926003599371282 0.926003599371282 0.926003599371282
Tead1 ENSMUSG00000055320 0.640861491578951 0.640861491578951 0.297095062262362 0.640861491578951 0.578113371816017 0.640861491578951
Pard6g ENSMUSG00000056214 0.711854160331342 0.926550375688041 0.926550375688041 0.926550375688041 0.454942951775341 0.926550375688041
Inadl ENSMUSG00000061859 0.300095920620217 0.900287761860652 0.926658283600152 1 1 1

ECM-receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col6a1 ENSMUSG00000001119 0.853801250889739 0.853801250889739 0.174692232033629 0.524076696100887 0.513665062682276 0.770497594023414
Itga2 ENSMUSG00000015533 0.295581119060361 0.443371678590541 0.29558111906036 0.443371678590541 0.450444934184774 0.450444934184774
Vtn ENSMUSG00000017344 0.21549027811633 0.646470834348989 0.78180291566155 1 1 1
Lama4 ENSMUSG00000019846 0.926333123228344 0.926333123228344 0.711854160331342 0.926333123228344 0.348008842235184 0.926333123228344
Thbs2 ENSMUSG00000023885 0.453570536021945 0.680355804032917 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501
Lama3 ENSMUSG00000024421 0.294820734456232 0.442231101684348 0.0592616003460512 0.177784801038154 0.926658283600152 0.926658283600152
Col9a1 ENSMUSG00000026147 0.853801250889739 0.853801250889739 0.179945789077372 0.539837367232115 0.514934023620344 0.772401035430517
Lamc1 ENSMUSG00000026478 0.21549027811633 0.64647083434899 0.78148726569172 0.78148726569172 0.455625354715449 0.683438032073173
Itga8 ENSMUSG00000026768 0.573205482926791 0.573205482926791 0.509798138101151 0.573205482926791 0.45596561163947 0.573205482926791
Itgav ENSMUSG00000027087 0.853480389728993 0.853480389728993 0.0162664168407233 0.04879925052217 0.120545895661628 0.180818843492441
Itga6 ENSMUSG00000027111 0.850721744111585 0.850721744111585 0.0241933715424143 0.0725801146272428 0.576112968612194 0.850721744111585
Col9a2 ENSMUSG00000028626 0.853694531487825 0.853694531487825 0.511742979522636 0.767614469283954 0.18064054691103 0.541921640733091
Spp1 ENSMUSG00000029304 0.926441990075769 0.926441990075769 0.0969812105731563 0.290943631719469 0.577829325134931 0.866743987702397
Col4a2 ENSMUSG00000031503 0.779888212132595 0.779888212132595 0.643359829732651 0.779888212132595 0.706616781330066 0.779888212132595
Frem2 ENSMUSG00000037016 0.577829325134931 0.711445446052875 0.711445446052875 0.711445446052875 0.643606811957488 0.711445446052875
Reln ENSMUSG00000042453 0.455625354715449 0.455625354715449 0.254414773803597 0.455625354715449 0.398108175780842 0.455625354715449
Gp1bb ENSMUSG00000050761 0.0763619660358786 0.114542949053818 0.640861491578951 0.640861491578951 0.0168921052924601 0.0506763158773803
Sv2c ENSMUSG00000051111 0.454942951775341 0.683948417459205 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155
Sv2b ENSMUSG00000053025 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152 0.711240436189781 0.926658283600152
Frem1 ENSMUSG00000059049 0.782117202022501 0.782117202022501 0.455625354715449 0.7733472349452 0.5155648232968 0.7733472349452

Tight junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tiam1 ENSMUSG00000002489 0.853480389728993 0.853480389728993 0.399548817627028 0.599323226440542 0.399548817627028 0.599323226440542
Prkag3 ENSMUSG00000006542 0.630041677094388 0.630041677094388 0.0615004988748111 0.184501496624433 0.25676053529128 0.38514080293692
Cdk4 ENSMUSG00000006728 0.926550375688041 0.926550375688041 0.711034989117171 0.926550375688041 0.853801250889739 0.926550375688041
Amotl1 ENSMUSG00000013076 0.399548817627028 0.639337105615665 0.453570536021945 0.639337105615665 0.639337105615665 0.639337105615665
Actn1 ENSMUSG00000015143 0.254787123615605 0.395928178642446 0.390750658104794 0.395928178642446 0.395928178642446 0.395928178642446
Cacna1d ENSMUSG00000015968 0.399548817627028 0.399548817627028 0.0384205930139141 0.115261779041742 0.397384062266614 0.399548817627028
Llgl1 ENSMUSG00000020536 0.0964252305385472 0.270960820366546 0.180640546911031 0.270960820366546 0.514300775319626 0.514300775319626
Map3k1 ENSMUSG00000021754 0.642864324224729 0.926333123228344 0.0969812105731563 0.290943631719469 0.926333123228344 0.926333123228344
Runx1 ENSMUSG00000022952 0.000143939694472871 0.000431819083418612 0.0756145297453646 0.113421794618047 0.514300775319626 0.514300775319626
Myl12a ENSMUSG00000024048 0.926333123228344 0.926333123228344 0.347639524025037 0.600398061312773 0.400265374208515 0.600398061312773
Ppp2r2b ENSMUSG00000024500 0.148772260628989 0.446316781886968 1 1 0.643853282854191 0.965779924281287
Pard3 ENSMUSG00000025812 0.853801250889739 0.92589277149125 0.639337105615665 0.92589277149125 0.92589277149125 0.92589277149125
Cd1d1 ENSMUSG00000028076 1 1 0.0763619660358786 0.229085898107636 0.711854160331342 1
Prkaa2 ENSMUSG00000028518 0.455625354715449 1 0.78180291566155 1 1 1
Prkag2 ENSMUSG00000028944 1 1 0.300095920620218 0.900287761860654 0.853907737111068 1
Prkab1 ENSMUSG00000029513 0.447621891168214 0.642366752097095 0.148115998140415 0.444347994421246 0.642366752097095 0.642366752097095
Tuba8 ENSMUSG00000030137 0.395928178642446 0.593892267963669 0.0168921052924602 0.0506763158773805 0.640355507848752 0.640355507848752
Vasp ENSMUSG00000030403 1 1 0.514934023620345 1 0.711650020253571 1
Myh14 ENSMUSG00000030739 0.214764523938593 0.64429357181578 0.853372965654504 0.853372965654504 0.711650020253571 0.853372965654504
Rdx ENSMUSG00000032050 0.643853282854191 0.853372965654504 0.513026869856283 0.853372965654504 0.853372965654504 0.853372965654504
Amotl2 ENSMUSG00000032531 0.21549027811633 0.375428758901986 0.400265374208515 0.400265374208515 0.250285839267991 0.375428758901986
Prkab2 ENSMUSG00000038205 0.782117202022501 0.782117202022501 0.454942951775341 0.682414427663012 0.204424977646738 0.613274932940215
Amot ENSMUSG00000041688 0.711854160331342 0.92622377157404 0.710416009055326 0.92622377157404 0.92622377157404 0.92622377157404
Ppp2r2d ENSMUSG00000041769 0.0171027900598199 0.0513083701794597 0.578113371816017 0.867170057724026 1 1
Tuba1c ENSMUSG00000043091 0.348008842235185 0.348008842235185 0.298599969973533 0.348008842235185 0.346527959006435 0.348008842235185
Magi1 ENSMUSG00000045095 0.0325051220296005 0.0975153660888015 0.270898788519615 0.390750658104794 0.390750658104794 0.390750658104794
Cldn14 ENSMUSG00000047109 0.0763619660358786 0.229085898107636 0.300095920620218 0.300095920620218 0.18064054691103 0.270960820366546
Jam2 ENSMUSG00000053062 0.514934023620344 0.772401035430517 0.148772260628989 0.446316781886967 1 1
Pard6g ENSMUSG00000056214 0.711854160331342 0.926550375688041 0.926550375688041 0.926550375688041 0.454942951775341 0.926550375688041
Inadl ENSMUSG00000061859 0.300095920620217 0.900287761860652 0.926658283600152 1 1 1
Cldn19 ENSMUSG00000066058 0.295581119060361 0.443371678590541 0.205174703261494 0.443371678590541 0.615734841980377 0.615734841980377
Map3k5 ENSMUSG00000071369 0.456305241393103 0.511742979522636 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636

Amphetamine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Th ENSMUSG00000000214 0.400265374208515 0.600398061312773 0.17924968721805 0.537749061654149 0.92622377157404 0.92622377157404
Calm1 ENSMUSG00000001175 0.643853282854191 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Grin2d ENSMUSG00000002771 0.0930846407079409 0.279253922123823 0.853480389728993 0.853480389728993 0.643359829732651 0.853480389728993
Ppp1cc ENSMUSG00000004455 1 1 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Cacna1d ENSMUSG00000015968 0.399548817627028 0.399548817627028 0.0384205930139141 0.115261779041742 0.397384062266614 0.399548817627028
Sirt1 ENSMUSG00000020063 0.643853282854191 0.965779924281287 1 1 0.643853282854191 0.965779924281287
Ddc ENSMUSG00000020182 0.853907737111068 1 1 1 0.254414773803596 0.763244321410789
Gria1 ENSMUSG00000020524 0.399548817627028 0.852832278580641 0.852832278580641 0.852832278580641 0.578113371816017 0.852832278580641
Slc6a3 ENSMUSG00000021609 0.452880492349546 0.679320738524319 0.211844580334808 0.635533741004424 0.779888212132595 0.779888212132595
Slc18a2 ENSMUSG00000025094 0.513665062682276 0.853801250889739 0.853801250889739 0.853801250889739 0.577259514257969 0.853801250889739
Hdac1 ENSMUSG00000028800 0.853480389728993 0.853480389728993 0.0964252305385471 0.289275691615641 0.78180291566155 0.853480389728993
Ppp3r1 ENSMUSG00000033953 0.853801250889739 0.853801250889739 0.348377561241889 0.853801250889739 0.712057867818062 0.853801250889739
Calm2 ENSMUSG00000036438 0.299349060054895 0.45596561163947 0.45596561163947 0.45596561163947 0.400265374208515 0.45596561163947
Camk4 ENSMUSG00000038128 0.577259514257969 0.642366752097095 0.642366752097095 0.642366752097095 0.252545530864481 0.642366752097095
Cacna1c ENSMUSG00000051331 0.397384062266614 0.596076093399921 0.0106683870753909 0.0320051612261727 0.635703516568382 0.635703516568382
Prkcb ENSMUSG00000052889 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517 0.782117202022501 0.782117202022501
Camk2b ENSMUSG00000057897 0.452880492349546 0.514934023620345 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345

Human papillomavirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccnd2 ENSMUSG00000000184 0.711034989117171 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041
Raf1 ENSMUSG00000000441 0.926441990075769 0.926441990075769 0.513665062682276 0.926441990075769 0.853372965654504 0.926441990075769
Tcf7 ENSMUSG00000000782 0.399548817627028 0.599323226440542 0.255901190956604 0.599323226440542 0.78180291566155 0.78180291566155
Col6a1 ENSMUSG00000001119 0.853801250889739 0.853801250889739 0.174692232033629 0.524076696100887 0.513665062682276 0.770497594023414
Ccne1 ENSMUSG00000002068 0.513665062682276 0.770497594023414 0.853372965654504 0.853372965654504 0.0331400397096515 0.0994201191289545
Cdk4 ENSMUSG00000006728 0.926550375688041 0.926550375688041 0.711034989117171 0.926550375688041 0.853801250889739 0.926550375688041
Ctnnb1 ENSMUSG00000006932 0.295581119060361 0.63250023504486 0.63250023504486 0.63250023504486 0.63086665720673 0.63250023504486
Itga2 ENSMUSG00000015533 0.295581119060361 0.443371678590541 0.29558111906036 0.443371678590541 0.450444934184774 0.450444934184774
Vtn ENSMUSG00000017344 0.21549027811633 0.646470834348989 0.78180291566155 1 1 1
Mfng ENSMUSG00000018169 0.177153312234059 0.443371678590541 0.703556284613037 0.703556284613037 0.295581119060361 0.443371678590541
Hey2 ENSMUSG00000019789 0.254414773803597 0.381622160705395 0.148115998140415 0.381622160705395 0.925444427431699 0.925444427431699
Lama4 ENSMUSG00000019846 0.926333123228344 0.926333123228344 0.711854160331342 0.926333123228344 0.348008842235184 0.926333123228344
Llgl1 ENSMUSG00000020536 0.0964252305385472 0.270960820366546 0.180640546911031 0.270960820366546 0.514300775319626 0.514300775319626
Atp6v1d ENSMUSG00000021114 0.0964252305385472 0.289275691615642 0.926550375688041 0.926550375688041 0.643853282854191 0.926550375688041
Psmc1 ENSMUSG00000021178 0.21549027811633 0.64647083434899 0.511742979522636 0.767614469283954 1 1
Wnt5a ENSMUSG00000021994 0.345037391052887 0.517556086579331 0.298599969973533 0.517556086579331 0.576973746230334 0.576973746230334
Ifnar2 ENSMUSG00000022971 0.146800541856249 0.440401625568746 1 1 0.711034989117171 1
Wnt10b ENSMUSG00000022996 0.454600801949285 0.513665062682276 0.014844565205092 0.0445336956152759 0.513665062682276 0.513665062682276
Mx2 ENSMUSG00000023341 0.178901132102685 0.268351698154027 0.0211129141819613 0.063338742545884 0.514934023620345 0.514934023620345
Thbs2 ENSMUSG00000023885 0.453570536021945 0.680355804032917 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501
Lama3 ENSMUSG00000024421 0.294820734456232 0.442231101684348 0.0592616003460512 0.177784801038154 0.926658283600152 0.926658283600152
Ppp2r2b ENSMUSG00000024500 0.148772260628989 0.446316781886968 1 1 0.643853282854191 0.965779924281287
Cdk2 ENSMUSG00000025358 0.781011212316137 0.781011212316137 0.346527959006435 0.781011212316137 0.643112334413352 0.781011212316137
Pard3 ENSMUSG00000025812 0.853801250889739 0.92589277149125 0.639337105615665 0.92589277149125 0.92589277149125 0.92589277149125
Stat1 ENSMUSG00000026104 0.297848640636702 0.599323226440542 0.399548817627028 0.599323226440542 0.638310022345193 0.638310022345193
Col9a1 ENSMUSG00000026147 0.853801250889739 0.853801250889739 0.179945789077372 0.539837367232115 0.514934023620344 0.772401035430517
Lamc1 ENSMUSG00000026478 0.21549027811633 0.64647083434899 0.78148726569172 0.78148726569172 0.455625354715449 0.683438032073173
Itga8 ENSMUSG00000026768 0.573205482926791 0.573205482926791 0.509798138101151 0.573205482926791 0.45596561163947 0.573205482926791
Itgav ENSMUSG00000027087 0.853480389728993 0.853480389728993 0.0162664168407233 0.04879925052217 0.120545895661628 0.180818843492441
Itga6 ENSMUSG00000027111 0.850721744111585 0.850721744111585 0.0241933715424143 0.0725801146272428 0.576112968612194 0.850721744111585
Jag1 ENSMUSG00000027276 0.254414773803597 0.381622160705395 0.0964252305385472 0.289275691615642 0.710416009055326 0.710416009055326
Ccna1 ENSMUSG00000027793 0.252170177483002 0.287481513930451 0.209267277690899 0.287481513930451 0.287481513930451 0.287481513930451
Notch2 ENSMUSG00000027878 0.395928178642446 0.593892267963669 0.0733738589968006 0.220121576990402 0.924872384323463 0.924872384323463
Egf ENSMUSG00000028017 0.577259514257969 0.7802108304765 0.254787123615605 0.764361370846816 0.7802108304765 0.7802108304765
Nfkb1 ENSMUSG00000028163 0.710208797518812 0.853801250889739 0.853801250889739 0.853801250889739 0.298599969973533 0.853801250889739
Col9a2 ENSMUSG00000028626 0.853694531487825 0.853694531487825 0.511742979522636 0.767614469283954 0.18064054691103 0.541921640733091
Hdac1 ENSMUSG00000028800 0.853480389728993 0.853480389728993 0.0964252305385471 0.289275691615641 0.78180291566155 0.853480389728993
Spp1 ENSMUSG00000029304 0.926441990075769 0.926441990075769 0.0969812105731563 0.290943631719469 0.577829325134931 0.866743987702397
Oasl2 ENSMUSG00000029561 0.174692232033629 0.31941411154781 0.212942741031873 0.31941411154781 0.924227671363131 0.924227671363131
Wnt16 ENSMUSG00000029671 0.514300775319626 0.853049270252403 0.853049270252403 0.853049270252403 0.711650020253571 0.853049270252403
Wnt7a ENSMUSG00000030093 0.711240436189781 0.7802108304765 0.173632433887832 0.520897301663497 0.7802108304765 0.7802108304765
Col4a2 ENSMUSG00000031503 0.779888212132595 0.779888212132595 0.643359829732651 0.779888212132595 0.706616781330066 0.779888212132595
Casp3 ENSMUSG00000031628 0.398108175780842 0.597162263671263 0.0432318933800775 0.129695680140233 0.642366752097095 0.642366752097095
Ptgs2 ENSMUSG00000032487 0.578113371816017 0.78180291566155 0.711854160331342 0.78180291566155 0.78180291566155 0.78180291566155
Heyl ENSMUSG00000032744 0.780851835278818 0.926333123228344 0.214037080764326 0.642111242292978 0.926333123228344 0.926333123228344
Wnt6 ENSMUSG00000033227 0.711240436189781 0.853372965654504 0.455625354715448 0.853372965654504 0.853372965654504 0.853372965654504
Isg15 ENSMUSG00000035692 0.342405296020881 0.593892267963669 0.395928178642446 0.593892267963669 0.781170242226513 0.781170242226513
Ppp2r2d ENSMUSG00000041769 0.0171027900598199 0.0513083701794597 0.578113371816017 0.867170057724026 1 1
Reln ENSMUSG00000042453 0.455625354715449 0.455625354715449 0.254414773803597 0.455625354715449 0.398108175780842 0.455625354715449
Foxo1 ENSMUSG00000044167 0.456305241393103 0.926658283600152 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Fzd5 ENSMUSG00000045005 0.853801250889739 0.853801250889739 0.455625354715449 0.853801250889739 0.711445446052875 0.853801250889739
Magi1 ENSMUSG00000045095 0.0325051220296005 0.0975153660888015 0.270898788519615 0.390750658104794 0.390750658104794 0.390750658104794
Hes5 ENSMUSG00000048001 0.456305241393103 0.456305241393103 0.454600801949285 0.456305241393103 0.398108175780842 0.456305241393103
Pard6g ENSMUSG00000056214 0.711854160331342 0.926550375688041 0.926550375688041 0.926550375688041 0.454942951775341 0.926550375688041
H2-K1 ENSMUSG00000061232 0.577259514257969 0.710416009055326 0.710416009055326 0.710416009055326 0.255901190956604 0.710416009055326
Inadl ENSMUSG00000061859 0.300095920620217 0.900287761860652 0.926658283600152 1 1 1
Chd4 ENSMUSG00000063870 0.707899741868332 0.707899741868332 0.455625354715449 0.683438032073173 0.342026805366747 0.683438032073173
C920025E04Rik ENSMUSG00000073405 0.853907737111068 0.926658283600152 0.345410946355104 0.926658283600152 0.926658283600152 0.926658283600152

blue4

[1] “No significantly overrepresented pathways reported”

blueviolet

Assembly of collagen fibrils and other multimeric structures

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp1 ENSMUSG00000022098 0.399548817627028 0.399548817627028 0.214764523938593 0.323235417174495 0.21549027811633 0.323235417174495
Loxl4 ENSMUSG00000025185 0.239102873501137 0.358654310251706 0.925444427431699 0.925444427431699 0.148048977551831 0.358654310251706
Col15a1 ENSMUSG00000028339 1 1 0.00737418180192506 0.0110612727028876 0.00737418180192505 0.0110612727028876
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col8a2 ENSMUSG00000056174 0.780692109850228 0.780692109850228 0.711034989117171 0.780692109850228 0.0323469380768477 0.0970408142305433
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

NCAM1 interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
St8sia2 ENSMUSG00000025789 0.395928178642446 0.399548817627028 0.399548817627028 0.399548817627028 0.29252580908486 0.399548817627028
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

Collagen biosynthesis and modifying enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp1 ENSMUSG00000022098 0.399548817627028 0.399548817627028 0.214764523938593 0.323235417174495 0.21549027811633 0.323235417174495
Col15a1 ENSMUSG00000028339 1 1 0.00737418180192506 0.0110612727028876 0.00737418180192505 0.0110612727028876
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col8a2 ENSMUSG00000056174 0.780692109850228 0.780692109850228 0.711034989117171 0.780692109850228 0.0323469380768477 0.0970408142305433
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

Collagen chain trimerization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col15a1 ENSMUSG00000028339 1 1 0.00737418180192506 0.0110612727028876 0.00737418180192505 0.0110612727028876
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col8a2 ENSMUSG00000056174 0.780692109850228 0.780692109850228 0.711034989117171 0.780692109850228 0.0323469380768477 0.0970408142305433
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

Collagen degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ctsd ENSMUSG00000007891 0.0579478375430679 0.173843512629204 0.926550375688041 0.926550375688041 0.346527959006435 0.519791938509652
Col15a1 ENSMUSG00000028339 1 1 0.00737418180192506 0.0110612727028876 0.00737418180192505 0.0110612727028876
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col8a2 ENSMUSG00000056174 0.780692109850228 0.780692109850228 0.711034989117171 0.780692109850228 0.0323469380768477 0.0970408142305433
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

Collagen formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp1 ENSMUSG00000022098 0.399548817627028 0.399548817627028 0.214764523938593 0.323235417174495 0.21549027811633 0.323235417174495
Loxl4 ENSMUSG00000025185 0.239102873501137 0.358654310251706 0.925444427431699 0.925444427431699 0.148048977551831 0.358654310251706
Col15a1 ENSMUSG00000028339 1 1 0.00737418180192506 0.0110612727028876 0.00737418180192505 0.0110612727028876
Col6a6 ENSMUSG00000043719 0.926333123228344 0.926333123228344 0.71082910328023 0.926333123228344 0.068902881791088 0.206708645373264
Col6a3 ENSMUSG00000048126 0.852065168704833 0.852065168704833 0.383900043565238 0.575850065347857 0.167569692867574 0.502709078602721
Col8a2 ENSMUSG00000056174 0.780692109850228 0.780692109850228 0.711034989117171 0.780692109850228 0.0323469380768477 0.0970408142305433
Col4a3 ENSMUSG00000079465 0.851732715229127 0.851732715229127 0.449391287230099 0.674086930845148 0.254414773803597 0.674086930845148

burlywood

[1] “No significantly overrepresented pathways reported”

chocolate2

[1] “No significantly overrepresented pathways reported”

chocolate4

Endocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Epn2 ENSMUSG00000001036 0.454600801949285 0.853694531487825 0.853694531487825 0.853694531487825 0.643359829732651 0.853694531487825
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Sh3gl1 ENSMUSG00000003200 0.926003599371282 0.926003599371282 0.643853282854191 0.926003599371282 0.345410946355104 0.926003599371282
Grk5 ENSMUSG00000003228 0.299349060054895 0.299349060054895 0.118714930081337 0.178072395122005 0.0432318933800775 0.129695680140232
Cyth2 ENSMUSG00000003269 0.853801250889739 1 0.45596561163947 1 1 1
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Stambp ENSMUSG00000006906 0.0566379395854604 0.119631084167592 0.119631084167592 0.119631084167592 0.0969812105731562 0.119631084167592
Git1 ENSMUSG00000011877 0.853480389728993 0.853480389728993 0.345037391052887 0.770497594023414 0.513665062682276 0.770497594023414
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Rab11fip4 ENSMUSG00000017639 0.926550375688041 0.926550375688041 0.454942951775342 0.866743987702397 0.577829325134931 0.866743987702397
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Snx3 ENSMUSG00000019804 0.453225835454266 0.629211154902385 0.629211154902385 0.629211154902385 0.450444934184774 0.629211154902385
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Amph ENSMUSG00000021314 0.853694531487825 0.853694531487825 0.779238691542963 0.853694531487825 0.575536202757516 0.853694531487825
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Agap3 ENSMUSG00000023353 0.513026869856283 0.769540304784424 0.852175490580835 0.852175490580835 0.346527959006435 0.769540304784424
Ehd3 ENSMUSG00000024065 0.852065168704833 0.9255572759333 0.9255572759333 0.9255572759333 0.454600801949285 0.9255572759333
Psd2 ENSMUSG00000024347 0.578113371816017 0.78180291566155 0.78180291566155 0.78180291566155 0.254787123615605 0.764361370846816
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Chmp6 ENSMUSG00000025371 0.178901132102685 0.514934023620344 0.514934023620344 0.514934023620344 0.348008842235184 0.514934023620344
Rnf41 ENSMUSG00000025373 0.45596561163947 0.683948417459205 0.7802108304765 0.7802108304765 0.252920381501207 0.683948417459205
Agap2 ENSMUSG00000025422 0.576973746230334 0.865460619345501 0.17750354896016 0.53251064688048 0.926550375688041 0.926550375688041
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Dnajc6 ENSMUSG00000028528 0.577829325134931 0.866743987702397 1 1 0.299349060054895 0.866743987702397
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Acap3 ENSMUSG00000029033 0.348008842235184 0.782117202022501 0.782117202022501 0.782117202022501 0.78180291566155 0.782117202022501
Psd3 ENSMUSG00000030465 0.346527959006435 0.926658283600152 0.926658283600152 0.926658283600152 0.853694531487825 0.926658283600152
Vps26b ENSMUSG00000031988 0.853049270252403 0.853049270252403 0.779888212132595 0.853049270252403 0.400265374208515 0.853049270252403
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Epn1 ENSMUSG00000035203 0.578113371816017 0.926441990075769 0.926441990075769 0.926441990075769 0.78148726569172 0.926441990075769
Psd ENSMUSG00000037126 0.216214347033994 0.648643041101983 0.780851835278818 0.780851835278818 0.454600801949285 0.681901202923927
Prkci ENSMUSG00000037643 0.0432318933800775 0.129695680140233 0.92622377157404 0.92622377157404 0.29252580908486 0.438788713627291
Chmp4b ENSMUSG00000038467 0.57466664340579 0.861999965108685 0.925217182211634 0.925217182211634 0.343537039781257 0.861999965108685
Smurf1 ENSMUSG00000038780 0.515249728559994 0.643112334413352 0.643112334413352 0.643112334413352 0.515249728559994 0.643112334413352
Iqsec2 ENSMUSG00000041115 0.78180291566155 0.78180291566155 0.455625354715449 0.78180291566155 0.711854160331342 0.78180291566155
Acap2 ENSMUSG00000049076 0.92622377157404 0.92622377157404 0.21549027811633 0.323235417174495 0.0969812105731562 0.290943631719469
Rab11fip5 ENSMUSG00000051343 0.780851835278818 0.780851835278818 0.398108175780842 0.597162263671263 0.295581119060361 0.597162263671263
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Asap2 ENSMUSG00000052632 0.711854160331342 1 1 1 0.254787123615606 0.764361370846817
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
H2-T23 ENSMUSG00000067212 0.400265374208515 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345
Arfgef2 ENSMUSG00000074582 0.146141353215796 0.379942095380391 0.643853282854191 0.643853282854191 0.253294730253594 0.379942095380391
Rab11b ENSMUSG00000077450 0.447265995733381 0.447265995733381 0.447265995733381 0.447265995733381 0.178901132102685 0.447265995733381
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

Autophagy - animal

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ulk2 ENSMUSG00000004798 0.21549027811633 0.576973746230334 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Sqstm1 ENSMUSG00000015837 1 1 0.852940894477647 1 0.216214347033995 0.648643041101984
Lamp2 ENSMUSG00000016534 0.0168921052924601 0.0506763158773803 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Atg10 ENSMUSG00000021619 0.398829756175299 0.598244634262948 0.0243249029874198 0.0729747089622593 0.643853282854191 0.643853282854191
Ctsb ENSMUSG00000021939 0.291756209988535 0.437634314982803 0.776243028387552 0.776243028387552 0.254787123615605 0.437634314982803
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Atg13 ENSMUSG00000027244 0.509144723230069 0.509144723230069 0.294820734456232 0.449023590082343 0.299349060054895 0.449023590082343
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Rragc ENSMUSG00000028646 0.453225835454266 0.453225835454266 0.0331400397096515 0.0994201191289544 0.346899083932133 0.453225835454266
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Atg7 ENSMUSG00000030314 0.78180291566155 0.78180291566155 0.450444934184774 0.675667401277161 0.255901190956604 0.675667401277161
Igbp1 ENSMUSG00000031221 0.853372965654504 0.853372965654504 0.577259514257969 0.853372965654504 0.450794830295118 0.853372965654504
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Atg9a ENSMUSG00000033124 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.34837756124189 0.781170242226513
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Dapk3 ENSMUSG00000034974 0.346527959006435 0.519791938509652 0.92622377157404 0.92622377157404 0.21549027811633 0.519791938509652
Uvrag ENSMUSG00000035354 0.781170242226513 0.781170242226513 0.300095920620218 0.781170242226513 0.711854160331342 0.781170242226513
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Rraga ENSMUSG00000070934 0.566593564630738 0.566593564630738 0.291756209988535 0.521459286037555 0.347639524025037 0.521459286037555
Atg4a ENSMUSG00000079418 0.78180291566155 0.78180291566155 0.256271555563966 0.384407333345949 0.250285839267991 0.384407333345949
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

Vasopressin-regulated water reabsorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Aqp4 ENSMUSG00000024411 0.712057867818062 0.712057867818062 0.255901190956604 0.449023590082343 0.299349060054895 0.449023590082343
Arhgdia ENSMUSG00000025132 0.641867098978198 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Arhgdig ENSMUSG00000073433 0.399548817627028 0.455625354715448 0.178901132102685 0.455625354715448 0.455625354715448 0.455625354715448
Rab11b ENSMUSG00000077450 0.447265995733381 0.447265995733381 0.447265995733381 0.447265995733381 0.178901132102685 0.447265995733381

Yersinia infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Arhgef28 ENSMUSG00000021662 0.346527959006435 0.7802108304765 0.7802108304765 0.7802108304765 0.642366752097095 0.7802108304765
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Was ENSMUSG00000031165 0.215127611919162 0.645382835757485 0.926604389137101 0.926604389137101 0.514617706526787 0.77192655979018
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Skap2 ENSMUSG00000059182 0.044926265292481 0.134778795877443 0.34837756124189 0.398829756175299 0.398829756175299 0.398829756175299
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Growth hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Gh ENSMUSG00000020713 0.0329809855655598 0.0494714783483397 0.0112279066750831 0.0336837200252494 0.0944774830993426 0.0944774830993426
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Sstr1 ENSMUSG00000035431 0.514934023620345 0.514934023620345 0.513665062682276 0.514934023620345 0.21549027811633 0.514934023620345
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Sstr3 ENSMUSG00000044933 0.78148726569172 0.78148726569172 0.147458757705094 0.442376273115283 0.711240436189781 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Sstr2 ENSMUSG00000047904 0.21549027811633 0.64647083434899 0.578113371816017 0.867170057724026 1 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Adrenergic signaling in cardiomyocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Scn1b ENSMUSG00000019194 0.45596561163947 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Tnnt2 ENSMUSG00000026414 0.643359829732651 0.643359829732651 0.347639524025037 0.643359829732651 0.576973746230334 0.643359829732651
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Adra1d ENSMUSG00000027335 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Adra1b ENSMUSG00000050541 1 1 0.782117202022501 1 0.578396848531894 1
Cacng8 ENSMUSG00000053395 0.852504981253341 0.92589277149125 0.456305241393103 0.92589277149125 0.92589277149125 0.92589277149125
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Myl3 ENSMUSG00000059741 0.00958959630219563 0.0287687889065869 0.146141353215796 0.219212029823694 0.296339225025931 0.296339225025931
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155

Fc gamma R-mediated phagocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Scin ENSMUSG00000002565 0.572616808177226 0.572616808177226 0.345410946355104 0.572616808177226 0.513665062682276 0.572616808177226
Hck ENSMUSG00000003283 5.62387620362729e-05 0.000168716286108819 0.216214347033995 0.216214347033995 0.0964252305385472 0.144637845807821
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Amph ENSMUSG00000021314 0.853694531487825 0.853694531487825 0.779238691542963 0.853694531487825 0.575536202757516 0.853694531487825
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Fcgr2b ENSMUSG00000026656 0.643853282854191 0.643853282854191 0.178901132102685 0.536703396308054 0.578396848531894 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Was ENSMUSG00000031165 0.215127611919162 0.645382835757485 0.926604389137101 0.926604389137101 0.514617706526787 0.77192655979018
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Asap2 ENSMUSG00000052632 0.711854160331342 1 1 1 0.254787123615606 0.764361370846817
Cfl1 ENSMUSG00000056201 0.711854160331342 0.853694531487825 0.853694531487825 0.853694531487825 0.781170242226513 0.853694531487825
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sema4f ENSMUSG00000000627 0.5155648232968 0.5155648232968 0.0964252305385472 0.289275691615642 0.255901190956604 0.383851786434906
Sema6b ENSMUSG00000001227 0.78180291566155 1 0.853372965654504 1 1 1
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Sema4d ENSMUSG00000021451 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516 0.120545895661628 0.361637686984883
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Boc ENSMUSG00000022687 0.576973746230334 0.926333123228344 0.78148726569172 0.926333123228344 0.926333123228344 0.926333123228344
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Slit1 ENSMUSG00000025020 0.204424977646738 0.306637466470107 0.514934023620345 0.514934023620345 0.0467563094579324 0.140268928373797
Ablim1 ENSMUSG00000025085 0.853801250889739 0.853801250889739 0.395196379647461 0.592794569471191 0.252545530864481 0.592794569471191
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Unc5a ENSMUSG00000025876 0.578113371816017 0.643359829732651 0.577259514257969 0.643359829732651 0.643359829732651 0.643359829732651
Sema4c ENSMUSG00000026121 0.179249687218049 0.268874530827074 0.348008842235184 0.348008842235184 0.0334587898203823 0.100376369461147
Epha4 ENSMUSG00000026235 0.577829325134931 0.866743987702397 0.348008842235184 0.866743987702397 0.926550375688041 0.926550375688041
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Ephb2 ENSMUSG00000028664 0.78180291566155 0.78180291566155 0.297095062262362 0.445642593393543 0.216214347033995 0.445642593393543
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Plxna4 ENSMUSG00000029765 0.216214347033995 0.449023590082343 0.78180291566155 0.78180291566155 0.299349060054895 0.449023590082343
Plxna1 ENSMUSG00000030084 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.294820734456232 0.642864324224729
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Neo1 ENSMUSG00000032340 0.513665062682276 0.770497594023414 0.852175490580835 0.852175490580835 0.180293335960318 0.540880007880955
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Sema7a ENSMUSG00000038264 0.400265374208515 0.867170057724026 0.926441990075769 0.926441990075769 0.578113371816017 0.867170057724026
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Lrrc4 ENSMUSG00000049939 0.712057867818062 0.712057867818062 0.711034989117171 0.712057867818062 0.397384062266614 0.712057867818062
Sema5b ENSMUSG00000052133 0.395196379647461 0.592794569471191 0.706831781264721 0.706831781264721 0.348008842235184 0.592794569471191
Rnd1 ENSMUSG00000054855 0.643853282854191 0.710208797518812 0.710208797518812 0.710208797518812 0.0964252305385472 0.289275691615642
Cfl1 ENSMUSG00000056201 0.711854160331342 0.853694531487825 0.853694531487825 0.853694531487825 0.781170242226513 0.853694531487825
Unc5c ENSMUSG00000059921 0.148444251782951 0.445332755348852 0.852832278580641 0.852832278580641 0.643112334413352 0.852832278580641
Nck2 ENSMUSG00000066877 1 1 0.513665062682276 0.770497594023414 0.399548817627028 0.770497594023414

Chemokine signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Grk5 ENSMUSG00000003228 0.299349060054895 0.299349060054895 0.118714930081337 0.178072395122005 0.0432318933800775 0.129695680140232
Hck ENSMUSG00000003283 5.62387620362729e-05 0.000168716286108819 0.216214347033995 0.216214347033995 0.0964252305385472 0.144637845807821
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Ccl25 ENSMUSG00000023235 0.78148726569172 0.853801250889739 0.711650020253571 0.853801250889739 0.853801250889739 0.853801250889739
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Ppbp ENSMUSG00000029372 0.214037080764326 0.214037080764326 0.0449262652924809 0.134778795877443 0.0969812105731562 0.145471815859734
Pf4 ENSMUSG00000029373 0.399548817627028 0.454600801949285 0.454600801949285 0.454600801949285 0.0583853430099096 0.175156029029729
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Was ENSMUSG00000031165 0.215127611919162 0.645382835757485 0.926604389137101 0.926604389137101 0.514617706526787 0.77192655979018
Cx3cl1 ENSMUSG00000031778 0.57466664340579 0.711854160331342 0.711854160331342 0.711854160331342 0.5155648232968 0.711854160331342
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Ccl7 ENSMUSG00000035373 0.630317283210151 0.920598771064439 0.110721602500731 0.332164807502194 0.920598771064439 0.920598771064439
Ccr7 ENSMUSG00000037944 0.514617706526787 0.77192655979018 0.117185073436597 0.351555220309791 0.780692109850228 0.780692109850228
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Prex1 ENSMUSG00000039621 0.399548817627028 0.456305241393103 0.252920381501207 0.456305241393103 0.456305241393103 0.456305241393103
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Cxcr5 ENSMUSG00000047880 0.47755817949663 0.716337269244944 0.924639851733043 0.924639851733043 0.108511603960209 0.325534811880627
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Cholinergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Kcnq2 ENSMUSG00000016346 0.926658283600152 0.926658283600152 0.711034989117171 0.926658283600152 0.643853282854191 0.926658283600152
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Chrna4 ENSMUSG00000027577 0.781170242226513 0.852940894477647 0.852940894477647 0.852940894477647 0.513665062682276 0.852940894477647
Kcnq4 ENSMUSG00000028631 0.256271555563966 0.768814666691898 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Chrm1 ENSMUSG00000032773 0.643359829732651 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

AMPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Cpt1c ENSMUSG00000007783 0.0964252305385472 0.144637845807821 0.00561257135151671 0.0168377140545501 0.211110344399808 0.211110344399808
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Pfkfb1 ENSMUSG00000025271 0.711034989117171 0.711034989117171 0.299349060054895 0.599323226440542 0.399548817627028 0.599323226440542
Pfkfb3 ENSMUSG00000026773 0.044737329683373 0.134211989050119 0.852832278580641 0.852832278580641 0.300095920620218 0.450143880930327
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Eef2k ENSMUSG00000035064 0.853480389728993 0.853480389728993 0.395928178642446 0.853480389728993 0.782117202022501 0.853480389728993
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Lepr ENSMUSG00000057722 0.711034989117171 0.711034989117171 0.640355507848752 0.711034989117171 0.255530331334266 0.711034989117171
Strada ENSMUSG00000069631 0.643853282854191 0.643853282854191 0.0753654386865988 0.226096316059796 0.5155648232968 0.643853282854191
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Rab11b ENSMUSG00000077450 0.447265995733381 0.447265995733381 0.447265995733381 0.447265995733381 0.178901132102685 0.447265995733381

Human cytomegalovirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Ptger1 ENSMUSG00000019464 0.92589277149125 0.92589277149125 0.852832278580641 0.92589277149125 0.116572120727418 0.349716362182253
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Il10rb ENSMUSG00000022969 0.399548817627028 0.926658283600152 0.92589277149125 0.926658283600152 0.926658283600152 0.926658283600152
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Calr4 ENSMUSG00000028558 0.348008842235184 0.522013263352777 0.148115998140415 0.444347994421246 0.926658283600152 0.926658283600152
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Cx3cl1 ENSMUSG00000031778 0.57466664340579 0.711854160331342 0.711854160331342 0.711854160331342 0.5155648232968 0.711854160331342
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-T23 ENSMUSG00000067212 0.400265374208515 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Endocrine resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Cdkn2c ENSMUSG00000028551 0.643359829732651 0.643359829732651 0.177153312234059 0.265729968351089 0.0588232673880151 0.176469802164045
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Regulation of lipolysis in adipocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Mgll ENSMUSG00000033174 0.399548817627028 0.7733472349452 0.926333123228344 0.926333123228344 0.5155648232968 0.7733472349452
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Adora1 ENSMUSG00000042429 0.711854160331342 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Fabp4 ENSMUSG00000062515 0.92616891281798 0.92616891281798 0.506837221875456 0.760255832813184 0.0950342596054052 0.285102778816216

Insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnn1 ENSMUSG00000002908 0.5155648232968 0.853480389728993 0.853480389728993 0.853480389728993 0.643359829732651 0.853480389728993
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Cck ENSMUSG00000032532 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Kcnmb4 ENSMUSG00000054934 1 1 0.398108175780842 0.866743987702397 0.577829325134931 0.866743987702397
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Longevity regulating pathway - multiple species

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Clpb ENSMUSG00000001829 0.570836132666921 0.856254199000382 1 1 0.252545530864481 0.757636592593443
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127

Rap1 signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.570836132666921 0.570836132666921 0.127987847862014 0.191981771793021 0.0579478375430677 0.173843512629203
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Rassf5 ENSMUSG00000026430 0.578113371816017 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Ctnnd1 ENSMUSG00000034101 0.45596561163947 0.683948417459205 0.926003599371282 0.926003599371282 0.295581119060361 0.683948417459205
Prkci ENSMUSG00000037643 0.0432318933800775 0.129695680140233 0.92622377157404 0.92622377157404 0.29252580908486 0.438788713627291
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Lpar4 ENSMUSG00000049929 0.578113371816017 0.643853282854191 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Magi3 ENSMUSG00000052539 0.0413659913978561 0.124097974193568 0.852940894477647 0.852940894477647 0.256271555563966 0.384407333345949
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rapgef2 ENSMUSG00000062232 0.852832278580641 0.852832278580641 0.640355507848752 0.852832278580641 0.452880492349546 0.852832278580641

Ras signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Rasgrf2 ENSMUSG00000021708 0.513026869856283 0.513026869856283 0.45596561163947 0.513026869856283 0.45596561163947 0.513026869856283
Ets2 ENSMUSG00000022895 0.577259514257969 0.577259514257969 0.0964252305385473 0.289275691615642 0.454942951775342 0.577259514257969
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Ralbp1 ENSMUSG00000024096 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.348008842235184 0.781170242226513
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Rassf5 ENSMUSG00000026430 0.578113371816017 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Rgl1 ENSMUSG00000026482 0.926333123228344 0.926333123228344 0.853372965654504 0.926333123228344 0.454942951775341 0.926333123228344
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Pla2g2f ENSMUSG00000028749 0.512386180848416 0.512386180848416 0.0716332429957515 0.214899728987254 0.343160411648938 0.512386180848416
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Brap ENSMUSG00000029458 0.853801250889739 0.853801250889739 0.576112968612194 0.853801250889739 0.514934023620345 0.853801250889739
Rasal1 ENSMUSG00000029602 0.711034989117171 0.711034989117171 0.0964252305385471 0.289275691615641 0.513026869856283 0.711034989117171
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Rgl2 ENSMUSG00000041354 0.573205482926791 0.860248370921054 1 1 0.573498913947369 0.860248370921054
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Ksr2 ENSMUSG00000061578 0.514617706526787 0.514617706526787 0.254041925545275 0.514617706526787 0.51270683838022 0.514617706526787
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Pancreatic cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Ralbp1 ENSMUSG00000024096 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.348008842235184 0.781170242226513
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Neurotrophin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Arhgdia ENSMUSG00000025132 0.641867098978198 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ntrk3 ENSMUSG00000059146 0.925444427431699 0.925444427431699 0.925331064166297 0.925444427431699 0.345037391052887 0.925444427431699
Sort1 ENSMUSG00000068747 0.853372965654504 0.853372965654504 0.577829325134931 0.853372965654504 0.642366752097095 0.853372965654504
Arhgdig ENSMUSG00000073433 0.399548817627028 0.455625354715448 0.178901132102685 0.455625354715448 0.455625354715448 0.455625354715448

Longevity regulating pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Atg13 ENSMUSG00000027244 0.509144723230069 0.509144723230069 0.294820734456232 0.449023590082343 0.299349060054895 0.449023590082343
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127

Th17 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stat6 ENSMUSG00000002147 0.575536202757516 0.711034989117171 0.711034989117171 0.711034989117171 0.710001140920767 0.711034989117171
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Ahr ENSMUSG00000019256 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.399548817627028 0.5155648232968
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Il21r ENSMUSG00000030745 0.0025036679180571 0.00751100375417131 0.299722768420014 0.44958415263002 0.78132892626786 0.78132892626786
Il4ra ENSMUSG00000030748 0.146141353215796 0.219212029823693 0.643853282854191 0.643853282854191 0.0756145297453649 0.219212029823693
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Rara ENSMUSG00000037992 0.297848640636702 0.576973746230334 0.399548817627028 0.576973746230334 0.576973746230334 0.576973746230334
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-Eb2 ENSMUSG00000067341 0.318952624781367 0.318952624781367 0.0620950549395545 0.186285164818663 0.318952624781367 0.318952624781367

Dopaminergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Maoa ENSMUSG00000025037 1 1 0.705968934865368 1 0.7802108304765 1
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B4galt7 ENSMUSG00000021504 0.455625354715448 0.455625354715448 0.146800541856249 0.323235417174495 0.21549027811633 0.323235417174495
Extl3 ENSMUSG00000021978 0.454600801949285 0.771451162979439 0.78180291566155 0.78180291566155 0.514300775319626 0.771451162979439
Extl1 ENSMUSG00000028838 0.643359829732651 0.643359829732651 0.578113371816017 0.643359829732651 0.577829325134931 0.643359829732651
Xylt1 ENSMUSG00000030657 0.643853282854191 0.643853282854191 0.299349060054895 0.643853282854191 0.577259514257969 0.643853282854191
Hs2st1 ENSMUSG00000040151 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155 0.180293335960318 0.540880007880955
Hs3st2 ENSMUSG00000046321 0.853801250889739 0.853801250889739 0.454600801949285 0.853801250889739 0.782117202022501 0.853801250889739
Ndst1 ENSMUSG00000054008 0.709375484777034 0.853049270252403 0.853049270252403 0.853049270252403 0.454600801949285 0.853049270252403
Ext1 ENSMUSG00000061731 0.347639524025037 0.521459286037555 0.148115998140416 0.444347994421247 0.926658283600152 0.926658283600152
B3gat3 ENSMUSG00000071649 0.255901190956604 0.383851786434906 0.575536202757516 0.575536202757516 0.252920381501206 0.383851786434906

Glycosphingolipid biosynthesis - ganglio series

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B4galnt1 ENSMUSG00000006731 0.853801250889739 0.926658283600152 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152
St8sia5 ENSMUSG00000025425 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.711034989117171 0.78148726569172
St6galnac6 ENSMUSG00000026811 0.300095920620218 0.450143880930327 0.643853282854191 0.643853282854191 0.299349060054895 0.450143880930327
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
St6galnac5 ENSMUSG00000039037 0.45596561163947 0.45596561163947 0.120850531362929 0.362551594088787 0.399548817627028 0.45596561163947
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
St6galnac4 ENSMUSG00000079442 0.299349060054895 0.449023590082343 0.575536202757516 0.575536202757516 0.173632433887832 0.449023590082343

Salmonella infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Cyth2 ENSMUSG00000003269 0.853801250889739 1 0.45596561163947 1 1 1
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Fhod1 ENSMUSG00000014778 0.117491334795683 0.176237002193525 0.0953125666339396 0.176237002193525 0.512386180848416 0.512386180848416
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Fyco1 ENSMUSG00000025241 0.5155648232968 0.5155648232968 0.455625354715449 0.5155648232968 0.514300775319626 0.5155648232968
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Vps33a ENSMUSG00000029434 0.578113371816017 0.867170057724026 0.926550375688041 0.926550375688041 0.45596561163947 0.867170057724026
Arl8b ENSMUSG00000030105 0.178901132102685 0.268351698154027 0.0436072256433733 0.13082167693012 0.642864324224729 0.642864324224729
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Vps18 ENSMUSG00000034216 0.780851835278818 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Actr1b ENSMUSG00000037351 0.398829756175299 0.399548817627028 0.288654423610209 0.399548817627028 0.399548817627028 0.399548817627028
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Naip5 ENSMUSG00000071203 0.643853282854191 0.781170242226513 0.146800541856249 0.440401625568746 0.781170242226513 0.781170242226513
Naip6 ENSMUSG00000078942 0.255901190956604 0.298224585822431 0.298224585822431 0.298224585822431 0.254041925545275 0.298224585822431
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

Relaxin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Rxfp1 ENSMUSG00000034009 0.711854160331342 0.853372965654504 0.578396848531894 0.853372965654504 0.853372965654504 0.853372965654504
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Apelin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Egr1 ENSMUSG00000038418 0.120545895661628 0.323235417174495 0.21549027811633 0.323235417174495 0.926658283600152 0.926658283600152
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Klf2 ENSMUSG00000055148 0.214764523938594 0.644293571815781 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Myl3 ENSMUSG00000059741 0.00958959630219563 0.0287687889065869 0.146141353215796 0.219212029823694 0.296339225025931 0.296339225025931
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

VEGF signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Oxytocin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Camk1g ENSMUSG00000016179 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593 0.255901190956604 0.677760882307593
Ppp1r12c ENSMUSG00000019254 0.0432318933800775 0.129695680140232 0.509144723230069 0.509144723230069 0.105759219123976 0.158638828685963
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Rgs2 ENSMUSG00000026360 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Eef2k ENSMUSG00000035064 0.853480389728993 0.853480389728993 0.395928178642446 0.853480389728993 0.782117202022501 0.853480389728993
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Myl6b ENSMUSG00000039824 1 1 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Cacng8 ENSMUSG00000053395 0.852504981253341 0.92589277149125 0.456305241393103 0.92589277149125 0.92589277149125 0.92589277149125
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155

Adipocytokine signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Cpt1c ENSMUSG00000007783 0.0964252305385472 0.144637845807821 0.00561257135151671 0.0168377140545501 0.211110344399808 0.211110344399808
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Acsl1 ENSMUSG00000018796 0.398108175780842 0.597162263671263 0.851061028660105 0.851061028660105 0.0936419271039908 0.280925781311972
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Acsl3 ENSMUSG00000032883 0.299349060054895 0.898047180164685 1 1 0.78148726569172 1
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Lepr ENSMUSG00000057722 0.711034989117171 0.711034989117171 0.640355507848752 0.711034989117171 0.255530331334266 0.711034989117171

Inflammatory mediator regulation of TRP channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Cyp2j9 ENSMUSG00000015224 0.45596561163947 0.853907737111068 0.853801250889739 0.853907737111068 0.853907737111068 0.853907737111068
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Trpv2 ENSMUSG00000018507 0.345037391052887 0.345037391052887 0.148772260628989 0.345037391052887 0.254414773803597 0.345037391052887
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Asic2 ENSMUSG00000020704 0.711240436189781 0.781170242226513 0.781170242226513 0.781170242226513 0.346527959006435 0.781170242226513
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Cyp2j6 ENSMUSG00000052914 0.926550375688041 0.926550375688041 0.21549027811633 0.64647083434899 0.782117202022501 0.926550375688041
Hrh1 ENSMUSG00000053004 0.781170242226513 0.781170242226513 0.180293335960318 0.270440003940477 0.17750354896016 0.270440003940477
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

EGFR tyrosine kinase inhibitor resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Gas6 ENSMUSG00000031451 0.7802108304765 1 1 1 0.214037080764326 0.642111242292977
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127

Salivary secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Adra1d ENSMUSG00000027335 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Dmbt1 ENSMUSG00000047517 0.111339700035808 0.334019100107424 0.704660273783604 0.704660273783604 0.620289042001438 0.704660273783604
Adra1b ENSMUSG00000050541 1 1 0.782117202022501 1 0.578396848531894 1
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Lyz2 ENSMUSG00000069516 0.0733738589968007 0.220121576990402 0.346527959006435 0.397384062266614 0.397384062266614 0.397384062266614

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt9a ENSMUSG00000000126 0.398829756175299 0.575536202757516 0.575536202757516 0.575536202757516 0.346527959006435 0.575536202757516
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Stat6 ENSMUSG00000002147 0.575536202757516 0.711034989117171 0.711034989117171 0.711034989117171 0.710001140920767 0.711034989117171
Ppard ENSMUSG00000002250 1 1 0.0334587898203824 0.100376369461147 0.254414773803597 0.381622160705395
Keap1 ENSMUSG00000003308 0.342405296020881 0.600398061312773 0.642366752097095 0.642366752097095 0.400265374208515 0.600398061312773
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Tpr ENSMUSG00000006005 0.572911448356892 0.78132892626786 0.78132892626786 0.78132892626786 0.710208797518812 0.78132892626786
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Msh3 ENSMUSG00000014850 0.641867098978197 0.711034989117171 0.711034989117171 0.711034989117171 0.254787123615605 0.711034989117171
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Ptger1 ENSMUSG00000019464 0.92589277149125 0.92589277149125 0.852832278580641 0.92589277149125 0.116572120727418 0.349716362182253
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Wnt7b ENSMUSG00000022382 1 1 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Ralbp1 ENSMUSG00000024096 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.348008842235184 0.781170242226513
Pmaip1 ENSMUSG00000024521 0.400265374208515 0.514934023620345 0.0964252305385471 0.289275691615641 0.514934023620345 0.514934023620345
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Wnt10a ENSMUSG00000026167 0.454942951775341 0.711034989117171 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171
Rassf5 ENSMUSG00000026430 0.578113371816017 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Lamc2 ENSMUSG00000026479 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155 0.5155648232968 0.78180291566155
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Il4ra ENSMUSG00000030748 0.146141353215796 0.219212029823693 0.643853282854191 0.643853282854191 0.0756145297453649 0.219212029823693
Pim2 ENSMUSG00000031155 0.255901190956604 0.400265374208515 0.399548817627028 0.400265374208515 0.400265374208515 0.400265374208515
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Egln1 ENSMUSG00000031987 0.449391287230099 0.509798138101151 0.509798138101151 0.509798138101151 0.18064054691103 0.509798138101151
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Cebpa ENSMUSG00000034957 0.514934023620345 0.865889271386954 0.577259514257969 0.865889271386954 1 1
Dapk3 ENSMUSG00000034974 0.346527959006435 0.519791938509652 0.92622377157404 0.92622377157404 0.21549027811633 0.519791938509652
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Rara ENSMUSG00000037992 0.297848640636702 0.576973746230334 0.399548817627028 0.576973746230334 0.576973746230334 0.576973746230334
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Hey1 ENSMUSG00000040289 0.711854160331342 0.853801250889739 0.144820068500793 0.43446020550238 0.853801250889739 0.853801250889739
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Lpar4 ENSMUSG00000049929 0.578113371816017 0.643853282854191 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Egln2 ENSMUSG00000058709 0.640861491578951 0.853049270252403 0.853049270252403 0.853049270252403 0.398829756175299 0.853049270252403
Ctnna2 ENSMUSG00000063063 0.400265374208515 0.400265374208515 0.120545895661628 0.361637686984883 0.397384062266614 0.400265374208515
Zbtb16 ENSMUSG00000066687 0.299349060054895 0.771451162979439 0.514300775319626 0.771451162979439 0.853694531487825 0.853694531487825
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Glutamatergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlgap1 ENSMUSG00000003279 0.711240436189781 0.853694531487825 0.255901190956604 0.767703572869812 0.853694531487825 0.853694531487825
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Shank2 ENSMUSG00000037541 0.254414773803597 0.763244321410791 0.509798138101151 0.764697207151727 0.92589277149125 0.92589277149125
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Autophagy - other

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ulk2 ENSMUSG00000004798 0.21549027811633 0.576973746230334 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Atg10 ENSMUSG00000021619 0.398829756175299 0.598244634262948 0.0243249029874198 0.0729747089622593 0.643853282854191 0.643853282854191
Atg13 ENSMUSG00000027244 0.509144723230069 0.509144723230069 0.294820734456232 0.449023590082343 0.299349060054895 0.449023590082343
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Atg7 ENSMUSG00000030314 0.78180291566155 0.78180291566155 0.450444934184774 0.675667401277161 0.255901190956604 0.675667401277161
Igbp1 ENSMUSG00000031221 0.853372965654504 0.853372965654504 0.577259514257969 0.853372965654504 0.450794830295118 0.853372965654504
Atg9a ENSMUSG00000033124 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.34837756124189 0.781170242226513
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Atg4a ENSMUSG00000079418 0.78180291566155 0.78180291566155 0.256271555563966 0.384407333345949 0.250285839267991 0.384407333345949

Kaposi sarcoma-associated herpesvirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Hck ENSMUSG00000003283 5.62387620362729e-05 0.000168716286108819 0.216214347033995 0.216214347033995 0.0964252305385472 0.144637845807821
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Tlr3 ENSMUSG00000031639 0.641867098978197 0.641867098978197 0.058823267388015 0.176469802164045 0.11810342389482 0.17715513584223
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Prex1 ENSMUSG00000039621 0.399548817627028 0.456305241393103 0.252920381501207 0.456305241393103 0.456305241393103 0.456305241393103
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-T23 ENSMUSG00000067212 0.400265374208515 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Platelet activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Fermt3 ENSMUSG00000024965 0.0443599545252852 0.133079863575856 0.853372965654504 0.853372965654504 0.348008842235184 0.522013263352777
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Fgb ENSMUSG00000033831 0.640861491578951 0.640861491578951 0.255901190956604 0.640861491578951 0.511742979522636 0.640861491578951
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Prkci ENSMUSG00000037643 0.0432318933800775 0.129695680140233 0.92622377157404 0.92622377157404 0.29252580908486 0.438788713627291
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327

Insulin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mknk2 ENSMUSG00000020190 0.926333123228344 0.926333123228344 0.851061028660105 0.926333123228344 0.501782052576058 0.926333123228344
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Phkg2 ENSMUSG00000030815 0.347639524025037 0.7733472349452 0.853801250889739 0.853801250889739 0.5155648232968 0.7733472349452
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Prkci ENSMUSG00000037643 0.0432318933800775 0.129695680140233 0.92622377157404 0.92622377157404 0.29252580908486 0.438788713627291
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Ppp1r3f ENSMUSG00000039556 0.573791743469336 0.573791743469336 0.573498913947369 0.573791743469336 0.25141795904251 0.573791743469336
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Ppp1r3a ENSMUSG00000042717 0.850608132982798 0.850608132982798 0.380389698508559 0.579886054111789 0.386590702741193 0.579886054111789
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Ppp1r3d ENSMUSG00000049999 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.643359829732651 0.782117202022501
Flot1 ENSMUSG00000059714 0.853907737111068 0.853907737111068 0.300095920620218 0.450143880930327 0.299349060054895 0.450143880930327
Ppp1r3c ENSMUSG00000067279 0.642366752097095 0.852065168704833 0.852065168704833 0.852065168704833 0.392243127063687 0.852065168704833

T cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Nck2 ENSMUSG00000066877 1 1 0.513665062682276 0.770497594023414 0.399548817627028 0.770497594023414

FoxO signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Nlk ENSMUSG00000017376 0.578396848531894 0.712057867818062 0.712057867818062 0.712057867818062 0.45596561163947 0.712057867818062
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Csnk1e ENSMUSG00000022433 0.180293335960318 0.540880007880955 0.400265374208515 0.600398061312773 0.640355507848752 0.640355507848752
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Agap2 ENSMUSG00000025422 0.576973746230334 0.865460619345501 0.17750354896016 0.53251064688048 0.926550375688041 0.926550375688041
Sgk3 ENSMUSG00000025915 0.297848640636702 0.446772960955053 0.711034989117171 0.711034989117171 0.0156504332881449 0.0469512998644348
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Foxo6 ENSMUSG00000052135 0.246861959455465 0.740585878366394 0.514934023620345 0.772401035430517 1 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Klf2 ENSMUSG00000055148 0.214764523938594 0.644293571815781 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Progesterone-mediated oocyte maturation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pgr ENSMUSG00000031870 0.454600801949285 0.454600801949285 0.295581119060361 0.447899954960299 0.298599969973533 0.447899954960299
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

ErbB signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Nck2 ENSMUSG00000066877 1 1 0.513665062682276 0.770497594023414 0.399548817627028 0.770497594023414
Btc ENSMUSG00000082361 0.0964252305385472 0.144637845807821 0.21549027811633 0.21549027811633 0.00731348855817121 0.0219404656745136

C-type lectin receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Lsp1 ENSMUSG00000018819 0.711650020253571 0.853049270252403 0.853049270252403 0.853049270252403 0.211844580334808 0.635533741004424
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Clec4d ENSMUSG00000030144 0.844059403278257 0.920870614561017 0.686412865145405 0.920870614561017 0.920870614561017 0.920870614561017
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Egr3 ENSMUSG00000033730 0.578113371816017 0.853480389728993 0.711240436189781 0.853480389728993 0.853480389728993 0.853480389728993
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Cd209c ENSMUSG00000040165 0.712057867818062 0.712057867818062 0.643853282854191 0.712057867818062 0.45596561163947 0.712057867818062
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Circadian entrainment

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Nos1ap ENSMUSG00000038473 0.853372965654504 0.926550375688041 0.926550375688041 0.926550375688041 0.642366752097095 0.926550375688041
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

cGMP-PKG signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Nppc ENSMUSG00000026241 0.17924968721805 0.516994836448954 0.926550375688041 0.926550375688041 0.344663224299303 0.516994836448954
Rgs2 ENSMUSG00000026360 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Adra1d ENSMUSG00000027335 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Adora1 ENSMUSG00000042429 0.711854160331342 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Irs3 ENSMUSG00000047182 0.044548558987246 0.133645676961738 0.853480389728993 0.853480389728993 0.510448974649398 0.765673461974097
Oprd1 ENSMUSG00000050511 0.779238691542963 0.779238691542963 0.399548817627028 0.599323226440542 0.395196379647461 0.599323226440542
Adra1b ENSMUSG00000050541 1 1 0.782117202022501 1 0.578396848531894 1
Kcnmb4 ENSMUSG00000054934 1 1 0.398108175780842 0.866743987702397 0.577829325134931 0.866743987702397

Focal adhesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Ppp1r12c ENSMUSG00000019254 0.0432318933800775 0.129695680140232 0.509144723230069 0.509144723230069 0.105759219123976 0.158638828685963
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Col6a2 ENSMUSG00000020241 0.576112968612194 0.641867098978198 0.17924968721805 0.537749061654149 0.641867098978198 0.641867098978198
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Parvg ENSMUSG00000022439 0.298599969973533 0.399548817627028 0.399548817627028 0.399548817627028 0.0328221470541517 0.098466441162455
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Itgb8 ENSMUSG00000025321 0.454600801949285 0.578396848531894 0.578396848531894 0.578396848531894 0.454600801949285 0.578396848531894
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Lamc2 ENSMUSG00000026479 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155 0.5155648232968 0.78180291566155
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Zyx ENSMUSG00000029860 0.712057867818062 0.712057867818062 0.5155648232968 0.712057867818062 0.643359829732651 0.712057867818062
Parva ENSMUSG00000030770 0.711240436189781 0.711240436189781 0.452880492349546 0.679320738524319 0.0579478375430677 0.173843512629203
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Hepatitis B

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Stat6 ENSMUSG00000002147 0.575536202757516 0.711034989117171 0.711034989117171 0.711034989117171 0.710001140920767 0.711034989117171
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Tlr3 ENSMUSG00000031639 0.641867098978197 0.641867098978197 0.058823267388015 0.176469802164045 0.11810342389482 0.17715513584223
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Egr3 ENSMUSG00000033730 0.578113371816017 0.853480389728993 0.711240436189781 0.853480389728993 0.853480389728993 0.853480389728993
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

One carbon pool by folate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shmt1 ENSMUSG00000020534 0.711240436189781 0.711240436189781 0.00289311433957183 0.00867934301871548 0.578113371816017 0.711240436189781
Gart ENSMUSG00000022962 0.853694531487825 0.853694531487825 0.575824878403157 0.853694531487825 0.643853282854191 0.853694531487825
Atic ENSMUSG00000026192 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.252545530864481 0.757636592593443
Aldh1l1 ENSMUSG00000030088 0.0964252305385472 0.181275797044394 1 1 0.120850531362929 0.181275797044394
Amt ENSMUSG00000032607 0.399548817627028 0.78180291566155 0.78180291566155 0.78180291566155 0.711650020253571 0.78180291566155
Mthfd1l ENSMUSG00000040675 0.7802108304765 0.7802108304765 0.642366752097095 0.7802108304765 0.345037391052887 0.7802108304765
Mtfmt ENSMUSG00000059183 0.575536202757516 0.575536202757516 0.45596561163947 0.575536202757516 0.453225835454266 0.575536202757516

Glioma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Camk1g ENSMUSG00000016179 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593 0.255901190956604 0.677760882307593
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Tight junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Marveld3 ENSMUSG00000001672 0.45253450475104 0.45253450475104 0.000736000256933431 0.00220800077080029 0.397746436553874 0.45253450475104
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Tjap1 ENSMUSG00000012296 0.515564823296799 0.773347234945198 0.853801250889739 0.853801250889739 0.144820068500793 0.434460205502379
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Hcls1 ENSMUSG00000022831 0.0936419271039908 0.280925781311972 0.779888212132595 0.779888212132595 0.711650020253571 0.779888212132595
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Mpdz ENSMUSG00000028402 0.92589277149125 0.92589277149125 0.398108175780842 0.597162263671263 0.248769231421035 0.597162263671263
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Tjp1 ENSMUSG00000030516 0.853372965654504 0.853372965654504 0.0443599545252853 0.133079863575856 0.141500034183268 0.212250051274902
Was ENSMUSG00000031165 0.215127611919162 0.645382835757485 0.926604389137101 0.926604389137101 0.514617706526787 0.77192655979018
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Prkci ENSMUSG00000037643 0.0432318933800775 0.129695680140233 0.92622377157404 0.92622377157404 0.29252580908486 0.438788713627291
Myl6b ENSMUSG00000039824 1 1 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Synpo ENSMUSG00000043079 1 1 0.782117202022501 1 0.926658283600152 1
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Cldn23 ENSMUSG00000055976 0.78180291566155 1 1 1 0.574957087247654 1
Rapgef2 ENSMUSG00000062232 0.852832278580641 0.852832278580641 0.640355507848752 0.852832278580641 0.452880492349546 0.852832278580641
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

PD-L1 expression and PD-1 checkpoint pathway in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Bacterial invasion of epithelial cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sept8 ENSMUSG00000018398 0.711854160331342 1 1 1 0.853694531487825 1
Sept3 ENSMUSG00000022456 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.345410946355104 0.78180291566155
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Hcls1 ENSMUSG00000022831 0.0936419271039908 0.280925781311972 0.779888212132595 0.779888212132595 0.711650020253571 0.779888212132595
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Sept9 ENSMUSG00000059248 0.5155648232968 0.7733472349452 0.853694531487825 0.853694531487825 0.513026869856283 0.7733472349452
Cd2ap ENSMUSG00000061665 0.710208797518812 0.710208797518812 0.216214347033995 0.648643041101984 0.5155648232968 0.710208797518812
Ctnna2 ENSMUSG00000063063 0.400265374208515 0.400265374208515 0.120545895661628 0.361637686984883 0.397384062266614 0.400265374208515
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Lipid and atherosclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Cyp2j9 ENSMUSG00000015224 0.45596561163947 0.853907737111068 0.853801250889739 0.853907737111068 0.853907737111068 0.853907737111068
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vldlr ENSMUSG00000024924 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636 0.454600801949285 0.511742979522636
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Atf6 ENSMUSG00000026663 1 1 0.711650020253571 1 0.782117202022501 1
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Apoa4 ENSMUSG00000032080 0.829591614328625 1 1 1 0.616658752687485 1
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Cyp2j6 ENSMUSG00000052914 0.926550375688041 0.926550375688041 0.21549027811633 0.64647083434899 0.782117202022501 0.926550375688041
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt9a ENSMUSG00000000126 0.398829756175299 0.575536202757516 0.575536202757516 0.575536202757516 0.346527959006435 0.575536202757516
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Ulk2 ENSMUSG00000004798 0.21549027811633 0.576973746230334 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Sqstm1 ENSMUSG00000015837 1 1 0.852940894477647 1 0.216214347033995 0.648643041101984
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Mapt ENSMUSG00000018411 0.853801250889739 0.853801250889739 0.454600801949285 0.681901202923927 0.255530331334266 0.681901202923927
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Ndufa12 ENSMUSG00000020022 0.214764523938594 0.644293571815782 0.454942951775341 0.682414427663012 0.92622377157404 0.92622377157404
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Uqcrb ENSMUSG00000021520 0.853801250889739 1 1 1 0.348008842235184 1
Gpx8 ENSMUSG00000021760 0.297848640636702 0.447899954960299 0.298599969973533 0.447899954960299 0.643853282854191 0.643853282854191
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Nefm ENSMUSG00000022054 0.926658283600152 0.926658283600152 0.514300775319626 0.926658283600152 0.926658283600152 0.926658283600152
Dnah5 ENSMUSG00000022262 0.255901190956604 0.383851786434906 0.711650020253571 0.711650020253571 0.252920381501207 0.383851786434906
Wnt7b ENSMUSG00000022382 1 1 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026
Csnk1e ENSMUSG00000022433 0.180293335960318 0.540880007880955 0.400265374208515 0.600398061312773 0.640355507848752 0.640355507848752
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Cox7a2l ENSMUSG00000024248 0.711650020253571 0.711650020253571 0.509798138101151 0.711650020253571 0.576973746230334 0.711650020253571
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Wnt10a ENSMUSG00000026167 0.454942951775341 0.711034989117171 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Atf6 ENSMUSG00000026663 1 1 0.711650020253571 1 0.782117202022501 1
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Atg13 ENSMUSG00000027244 0.509144723230069 0.509144723230069 0.294820734456232 0.449023590082343 0.299349060054895 0.449023590082343
Ube2j1 ENSMUSG00000028277 0.179945789077372 0.216214347033995 0.214037080764326 0.216214347033995 0.216214347033995 0.216214347033995
Mfn2 ENSMUSG00000029020 0.346527959006434 0.679320738524319 0.926550375688041 0.926550375688041 0.452880492349546 0.679320738524319
Uchl1 ENSMUSG00000029223 0.643853282854191 0.643853282854191 0.0443599545252853 0.133079863575856 0.5155648232968 0.643853282854191
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Nox4 ENSMUSG00000030562 0.455625354715449 0.683438032073173 0.711034989117171 0.711034989117171 0.0969812105731563 0.290943631719469
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Chrm1 ENSMUSG00000032773 0.643359829732651 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Actr1b ENSMUSG00000037351 0.398829756175299 0.399548817627028 0.288654423610209 0.399548817627028 0.399548817627028 0.399548817627028
Map3k10 ENSMUSG00000040390 0.299349060054895 0.683948417459205 1 1 0.45596561163947 0.683948417459205
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Cdk5r1 ENSMUSG00000048895 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152 0.782117202022501 0.926658283600152
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
mt-Co3 ENSMUSG00000064358 0.256271555563966 0.384407333345949 0.642864324224729 0.642864324224729 0.216214347033995 0.384407333345949
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Sept5 ENSMUSG00000072214 0.299349060054895 0.898047180164686 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Prnp ENSMUSG00000079037 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.120850531362929 0.362551594088788

Glucagon signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Cpt1c ENSMUSG00000007783 0.0964252305385472 0.144637845807821 0.00561257135151671 0.0168377140545501 0.211110344399808 0.211110344399808
Pgam1 ENSMUSG00000011752 0.853372965654504 0.926333123228344 0.926333123228344 0.926333123228344 0.578113371816017 0.926333123228344
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Pfkfb1 ENSMUSG00000025271 0.711034989117171 0.711034989117171 0.299349060054895 0.599323226440542 0.399548817627028 0.599323226440542
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Ldhb ENSMUSG00000030246 0.782117202022501 0.782117202022501 0.0964252305385472 0.289275691615642 0.782117202022501 0.782117202022501
Phkg2 ENSMUSG00000030815 0.347639524025037 0.7733472349452 0.853801250889739 0.853801250889739 0.5155648232968 0.7733472349452
Pkm ENSMUSG00000032294 1 1 0.92589277149125 1 0.346527959006435 1
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424

SNARE interactions in vesicular transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Vti1a ENSMUSG00000024983 0.926003599371282 0.926003599371282 0.576112968612194 0.864169452918291 0.300095920620218 0.864169452918291
Stx6 ENSMUSG00000026470 0.0969812105731563 0.290943631719469 0.852065168704833 0.852065168704833 0.216214347033995 0.324321520550992
Vamp1 ENSMUSG00000030337 0.578113371816017 0.578113371816017 0.0953125666339397 0.285937699901819 0.298599969973533 0.447899954960299
Stx1b ENSMUSG00000030806 1 1 0.577259514257969 0.865889271386954 0.5155648232968 0.865889271386954
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842

Acute myeloid leukemia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppard ENSMUSG00000002250 1 1 0.0334587898203824 0.100376369461147 0.254414773803597 0.381622160705395
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Pim2 ENSMUSG00000031155 0.255901190956604 0.400265374208515 0.399548817627028 0.400265374208515 0.400265374208515 0.400265374208515
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Cebpa ENSMUSG00000034957 0.514934023620345 0.865889271386954 0.577259514257969 0.865889271386954 1 1
Rara ENSMUSG00000037992 0.297848640636702 0.576973746230334 0.399548817627028 0.576973746230334 0.576973746230334 0.576973746230334
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Zbtb16 ENSMUSG00000066687 0.299349060054895 0.771451162979439 0.514300775319626 0.771451162979439 0.853694531487825 0.853694531487825
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Tuberculosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.570836132666921 0.570836132666921 0.127987847862014 0.191981771793021 0.0579478375430677 0.173843512629203
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Lamp2 ENSMUSG00000016534 0.0168921052924601 0.0506763158773803 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Lsp1 ENSMUSG00000018819 0.711650020253571 0.853049270252403 0.853049270252403 0.853049270252403 0.211844580334808 0.635533741004424
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Nfyb ENSMUSG00000020248 0.78180291566155 0.92589277149125 0.577259514257969 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Il10rb ENSMUSG00000022969 0.399548817627028 0.926658283600152 0.92589277149125 0.926658283600152 0.926658283600152 0.926658283600152
Atp6v0c ENSMUSG00000024121 0.509144723230068 0.509144723230068 0.491192352323595 0.509144723230068 0.340887582990546 0.509144723230068
Fcgr2b ENSMUSG00000026656 0.643853282854191 0.643853282854191 0.178901132102685 0.536703396308054 0.578396848531894 0.643853282854191
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Cd209c ENSMUSG00000040165 0.712057867818062 0.712057867818062 0.643853282854191 0.712057867818062 0.45596561163947 0.712057867818062
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-Eb2 ENSMUSG00000067341 0.318952624781367 0.318952624781367 0.0620950549395545 0.186285164818663 0.318952624781367 0.318952624781367
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

Synaptic vesicle cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Atp6v1b2 ENSMUSG00000006273 0.514934023620345 0.711854160331342 0.348008842235184 0.711854160331342 0.711854160331342 0.711854160331342
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Atp6v0c ENSMUSG00000024121 0.509144723230068 0.509144723230068 0.491192352323595 0.509144723230068 0.340887582990546 0.509144723230068
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Stx1b ENSMUSG00000030806 1 1 0.577259514257969 0.865889271386954 0.5155648232968 0.865889271386954
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Rims1 ENSMUSG00000041670 0.781170242226513 1 1 1 0.853801250889739 1
Slc6a7 ENSMUSG00000052026 0.515564823296799 0.773347234945198 0.513026869856283 0.773347234945198 0.782117202022501 0.782117202022501
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1

HIF-1 signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mknk2 ENSMUSG00000020190 0.926333123228344 0.926333123228344 0.851061028660105 0.926333123228344 0.501782052576058 0.926333123228344
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Pfkfb3 ENSMUSG00000026773 0.044737329683373 0.134211989050119 0.852832278580641 0.852832278580641 0.300095920620218 0.450143880930327
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Ldhb ENSMUSG00000030246 0.782117202022501 0.782117202022501 0.0964252305385472 0.289275691615642 0.782117202022501 0.782117202022501
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Egln1 ENSMUSG00000031987 0.449391287230099 0.509798138101151 0.509798138101151 0.509798138101151 0.18064054691103 0.509798138101151
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Egln2 ENSMUSG00000058709 0.640861491578951 0.853049270252403 0.853049270252403 0.853049270252403 0.398829756175299 0.853049270252403

cAMP signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Acox1 ENSMUSG00000020777 1 1 0.505169133438821 0.757753700158231 0.256271555563966 0.757753700158231
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Acox3 ENSMUSG00000029098 0.633039971999413 0.633039971999413 0.25141795904251 0.377126938563765 0.0241933715424143 0.0725801146272428
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Grin2b ENSMUSG00000030209 0.711854160331342 0.853801250889739 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Chrm1 ENSMUSG00000032773 0.643359829732651 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Sstr1 ENSMUSG00000035431 0.514934023620345 0.514934023620345 0.513665062682276 0.514934023620345 0.21549027811633 0.514934023620345
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Adora1 ENSMUSG00000042429 0.711854160331342 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Sstr2 ENSMUSG00000047904 0.21549027811633 0.64647083434899 0.578113371816017 0.867170057724026 1 1
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1

PI3K-Akt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Col6a2 ENSMUSG00000020241 0.576112968612194 0.641867098978198 0.17924968721805 0.537749061654149 0.641867098978198 0.641867098978198
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Gh ENSMUSG00000020713 0.0329809855655598 0.0494714783483397 0.0112279066750831 0.0336837200252494 0.0944774830993426 0.0944774830993426
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Itgb8 ENSMUSG00000025321 0.454600801949285 0.578396848531894 0.578396848531894 0.578396848531894 0.454600801949285 0.578396848531894
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Sgk3 ENSMUSG00000025915 0.297848640636702 0.446772960955053 0.711034989117171 0.711034989117171 0.0156504332881449 0.0469512998644348
Lamc2 ENSMUSG00000026479 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155 0.5155648232968 0.78180291566155
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Il4ra ENSMUSG00000030748 0.146141353215796 0.219212029823693 0.643853282854191 0.643853282854191 0.0756145297453649 0.219212029823693
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Phlpp2 ENSMUSG00000031732 0.118714930081337 0.118714930081337 0.0741204440774082 0.118714930081337 0.117185073436597 0.118714930081337
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Chrm1 ENSMUSG00000032773 0.643359829732651 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Lpar4 ENSMUSG00000049929 0.578113371816017 0.643853282854191 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Nlk ENSMUSG00000017376 0.578396848531894 0.712057867818062 0.712057867818062 0.712057867818062 0.45596561163947 0.712057867818062
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Mapt ENSMUSG00000018411 0.853801250889739 0.853801250889739 0.454600801949285 0.681901202923927 0.255530331334266 0.681901202923927
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mknk2 ENSMUSG00000020190 0.926333123228344 0.926333123228344 0.851061028660105 0.926333123228344 0.501782052576058 0.926333123228344
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Rasgrf2 ENSMUSG00000021708 0.513026869856283 0.513026869856283 0.45596561163947 0.513026869856283 0.45596561163947 0.513026869856283
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Mapk8ip2 ENSMUSG00000022619 0.711854160331342 0.926550375688041 0.926550375688041 0.926550375688041 0.578113371816017 0.926550375688041
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Map4k3 ENSMUSG00000024242 0.249528554620971 0.599323226440542 0.781170242226513 0.781170242226513 0.399548817627028 0.599323226440542
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
Mapk8ip1 ENSMUSG00000027223 0.348008842235184 0.600398061312773 0.78180291566155 0.78180291566155 0.400265374208515 0.600398061312773
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Cacng8 ENSMUSG00000053395 0.852504981253341 0.92589277149125 0.456305241393103 0.92589277149125 0.92589277149125 0.92589277149125
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Rapgef2 ENSMUSG00000062232 0.852832278580641 0.852832278580641 0.640355507848752 0.852832278580641 0.452880492349546 0.852832278580641
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155

Non-small cell lung cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Rassf5 ENSMUSG00000026430 0.578113371816017 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Mitophagy - animal

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Sqstm1 ENSMUSG00000015837 1 1 0.852940894477647 1 0.216214347033995 0.648643041101984
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Bnip3l ENSMUSG00000022051 0.398108175780842 0.398108175780842 0.121155015244363 0.363465045733089 0.398108175780842 0.398108175780842
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Mfn2 ENSMUSG00000029020 0.346527959006434 0.679320738524319 0.926550375688041 0.926550375688041 0.452880492349546 0.679320738524319
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Gabarapl1 ENSMUSG00000030161 0.511742979522636 0.511742979522636 0.501782052576058 0.511742979522636 0.254414773803597 0.511742979522636
Atg9a ENSMUSG00000033124 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.34837756124189 0.781170242226513
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

AGE-RAGE signaling pathway in diabetic complications

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Nox4 ENSMUSG00000030562 0.455625354715449 0.683438032073173 0.711034989117171 0.711034989117171 0.0969812105731563 0.290943631719469
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Egr1 ENSMUSG00000038418 0.120545895661628 0.323235417174495 0.21549027811633 0.323235417174495 0.926658283600152 0.926658283600152
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Fc epsilon RI signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Aldosterone synthesis and secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Camk1g ENSMUSG00000016179 0.781170242226513 0.781170242226513 0.451840588205062 0.677760882307593 0.255901190956604 0.677760882307593
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Daglb ENSMUSG00000039206 0.120545895661628 0.361637686984883 0.706831781264721 0.706831781264721 0.642366752097095 0.706831781264721
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Kcnk3 ENSMUSG00000049265 0.578396848531894 0.578396848531894 0.513026869856283 0.578396848531894 0.514934023620345 0.578396848531894

Th1 and Th2 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stat6 ENSMUSG00000002147 0.575536202757516 0.711034989117171 0.711034989117171 0.711034989117171 0.710001140920767 0.711034989117171
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Zap70 ENSMUSG00000026117 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.0168921052924602 0.0506763158773805
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Il4ra ENSMUSG00000030748 0.146141353215796 0.219212029823693 0.643853282854191 0.643853282854191 0.0756145297453649 0.219212029823693
Rbpj ENSMUSG00000039191 0.000394209637342661 0.00118262891202798 0.781170242226513 0.781170242226513 0.348008842235184 0.522013263352776
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-Eb2 ENSMUSG00000067341 0.318952624781367 0.318952624781367 0.0620950549395545 0.186285164818663 0.318952624781367 0.318952624781367

Mannose type O-glycan biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Large ENSMUSG00000004383 0.5155648232968 0.711650020253571 0.711650020253571 0.711650020253571 0.643853282854191 0.711650020253571
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Mgat5b ENSMUSG00000043857 0.640861491578951 0.853372965654504 0.454600801949285 0.853372965654504 0.853372965654504 0.853372965654504
B3gnt1 ENSMUSG00000047379 0.7802108304765 0.7802108304765 0.707899741868332 0.7802108304765 0.299349060054895 0.7802108304765
Fkrp ENSMUSG00000048920 0.926550375688041 0.926658283600152 0.926658283600152 0.926658283600152 0.643853282854191 0.926658283600152
Pomgnt2 ENSMUSG00000066235 0.642117186565222 0.642117186565222 0.120545895661627 0.361637686984882 0.254041925545275 0.381062888317912

Toxoplasmosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Il10rb ENSMUSG00000022969 0.399548817627028 0.926658283600152 0.92589277149125 0.926658283600152 0.926658283600152 0.926658283600152
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Lamc2 ENSMUSG00000026479 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155 0.5155648232968 0.78180291566155
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
H2-Eb2 ENSMUSG00000067341 0.318952624781367 0.318952624781367 0.0620950549395545 0.186285164818663 0.318952624781367 0.318952624781367

Insulin resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Slc27a3 ENSMUSG00000027932 0.513026869856283 0.513026869856283 0.17924968721805 0.513026869856283 0.342026805366747 0.513026869856283
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tbc1d4 ENSMUSG00000033083 0.299349060054895 0.898047180164686 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Ppp1r3a ENSMUSG00000042717 0.850608132982798 0.850608132982798 0.380389698508559 0.579886054111789 0.386590702741193 0.579886054111789
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Ppp1r3d ENSMUSG00000049999 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.643359829732651 0.782117202022501
Slc27a4 ENSMUSG00000059316 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.642366752097095 0.711034989117171
Ppp1r3c ENSMUSG00000067279 0.642366752097095 0.852065168704833 0.852065168704833 0.852065168704833 0.392243127063687 0.852065168704833

Sphingolipid signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Sgpp2 ENSMUSG00000032908 0.450444934184774 0.456305241393103 0.0746183450292887 0.223855035087866 0.456305241393103 0.456305241393103
Smpd1 ENSMUSG00000037049 0.712057867818062 0.712057867818062 0.570836132666921 0.712057867818062 0.297848640636702 0.712057867818062
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Sgms1 ENSMUSG00000040451 0.926658283600152 0.926658283600152 0.300095920620218 0.450143880930327 0.0753654386865988 0.226096316059796
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Adora1 ENSMUSG00000042429 0.711854160331342 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Oprd1 ENSMUSG00000050511 0.779238691542963 0.779238691542963 0.399548817627028 0.599323226440542 0.395196379647461 0.599323226440542
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
S1pr3 ENSMUSG00000067586 0.297095062262362 0.445642593393544 0.573498913947369 0.573498913947369 0.119631084167592 0.358893252502775

Colorectal cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Msh3 ENSMUSG00000014850 0.641867098978197 0.711034989117171 0.711034989117171 0.711034989117171 0.254787123615605 0.711034989117171
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Pmaip1 ENSMUSG00000024521 0.400265374208515 0.514934023620345 0.0964252305385471 0.289275691615641 0.514934023620345 0.514934023620345
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Leukocyte transendothelial migration

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.570836132666921 0.570836132666921 0.127987847862014 0.191981771793021 0.0579478375430677 0.173843512629203
Esam ENSMUSG00000001946 0.255901190956604 0.383851786434906 0.926333123228344 0.926333123228344 0.0761127945805735 0.22833838374172
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Rassf5 ENSMUSG00000026430 0.578113371816017 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Ctnnd1 ENSMUSG00000034101 0.45596561163947 0.683948417459205 0.926003599371282 0.926003599371282 0.295581119060361 0.683948417459205
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Cldn23 ENSMUSG00000055976 0.78180291566155 1 1 1 0.574957087247654 1
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Ctnna2 ENSMUSG00000063063 0.400265374208515 0.400265374208515 0.120545895661628 0.361637686984883 0.397384062266614 0.400265374208515

Gastric acid secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Sstr2 ENSMUSG00000047904 0.21549027811633 0.64647083434899 0.578113371816017 0.867170057724026 1 1
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041

Regulation of actin cytoskeleton

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.570836132666921 0.570836132666921 0.127987847862014 0.191981771793021 0.0579478375430677 0.173843512629203
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Scin ENSMUSG00000002565 0.572616808177226 0.572616808177226 0.345410946355104 0.572616808177226 0.513665062682276 0.572616808177226
Git1 ENSMUSG00000011877 0.853480389728993 0.853480389728993 0.345037391052887 0.770497594023414 0.513665062682276 0.770497594023414
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Pip4k2b ENSMUSG00000018547 0.926441990075769 1 1 1 0.45596561163947 1
Ppp1r12c ENSMUSG00000019254 0.0432318933800775 0.129695680140232 0.509144723230069 0.509144723230069 0.105759219123976 0.158638828685963
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Itgb8 ENSMUSG00000025321 0.454600801949285 0.578396848531894 0.578396848531894 0.578396848531894 0.454600801949285 0.578396848531894
Pip4k2c ENSMUSG00000025417 0.5155648232968 0.642366752097095 0.642366752097095 0.642366752097095 0.577829325134931 0.642366752097095
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arpc5l ENSMUSG00000026755 0.578113371816017 0.782117202022501 0.0443599545252853 0.133079863575856 0.782117202022501 0.782117202022501
Fgf7 ENSMUSG00000027208 0.576112968612194 0.710208797518812 0.00477055016690543 0.0143116505007163 0.710208797518812 0.710208797518812
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Chrm1 ENSMUSG00000032773 0.643359829732651 0.853480389728993 0.34837756124189 0.853480389728993 0.853480389728993 0.853480389728993
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Chrm3 ENSMUSG00000046159 0.781170242226513 0.781170242226513 0.7802108304765 0.781170242226513 0.399548817627028 0.781170242226513
Lpar4 ENSMUSG00000049929 0.578113371816017 0.643853282854191 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Cfl1 ENSMUSG00000056201 0.711854160331342 0.853694531487825 0.853694531487825 0.853694531487825 0.781170242226513 0.853694531487825
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

GnRH signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Egr1 ENSMUSG00000038418 0.120545895661628 0.323235417174495 0.21549027811633 0.323235417174495 0.926658283600152 0.926658283600152
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Estrogen signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pgr ENSMUSG00000031870 0.454600801949285 0.454600801949285 0.295581119060361 0.447899954960299 0.298599969973533 0.447899954960299
Krt20 ENSMUSG00000035775 0.397746436553874 0.454258017332816 0.454258017332816 0.454258017332816 0.252545530864481 0.454258017332816
Rara ENSMUSG00000037992 0.297848640636702 0.576973746230334 0.399548817627028 0.576973746230334 0.576973746230334 0.576973746230334
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424

Morphine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.640355507848752 0.711650020253571 0.57466664340579 0.711650020253571 0.711650020253571 0.711650020253571
Grk5 ENSMUSG00000003228 0.299349060054895 0.299349060054895 0.118714930081337 0.178072395122005 0.0432318933800775 0.129695680140232
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Adora1 ENSMUSG00000042429 0.711854160331342 0.853907737111068 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Central carbon metabolism in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Pgam1 ENSMUSG00000011752 0.853372965654504 0.926333123228344 0.926333123228344 0.926333123228344 0.578113371816017 0.926333123228344
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Idh1 ENSMUSG00000025950 0.926441990075769 0.926441990075769 0.926333123228344 0.926441990075769 0.853694531487825 0.926441990075769
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Ldhb ENSMUSG00000030246 0.782117202022501 0.782117202022501 0.0964252305385472 0.289275691615642 0.782117202022501 0.782117202022501
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Pkm ENSMUSG00000032294 1 1 0.92589277149125 1 0.346527959006435 1
9630033F20Rik ENSMUSG00000038028 0.348008842235184 0.926550375688041 0.926550375688041 0.926550375688041 0.643853282854191 0.926550375688041
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Slc7a5 ENSMUSG00000040010 0.577829325134931 0.643359829732651 0.643359829732651 0.643359829732651 0.058823267388015 0.176469802164045
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Ntrk3 ENSMUSG00000059146 0.925444427431699 0.925444427431699 0.925331064166297 0.925444427431699 0.345037391052887 0.925444427431699

Thyroid hormone signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Med24 ENSMUSG00000017210 0.576112968612194 0.853372965654504 0.853372965654504 0.853372965654504 0.513665062682276 0.853372965654504
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Slc16a10 ENSMUSG00000019838 0.0964252305385472 0.289275691615642 0.778911768167544 0.778911768167544 0.638824656785692 0.778911768167544
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tbc1d4 ENSMUSG00000033083 0.299349060054895 0.898047180164686 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Thra ENSMUSG00000058756 0.514934023620344 0.772401035430517 0.926333123228344 0.926333123228344 0.300095920620218 0.772401035430517
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

B cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Nfkbie ENSMUSG00000023947 0.456305241393103 0.770497594023414 0.852940894477647 0.852940894477647 0.513665062682276 0.770497594023414
Fcgr2b ENSMUSG00000026656 0.643853282854191 0.643853282854191 0.178901132102685 0.536703396308054 0.578396848531894 0.643853282854191
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501

Human T-cell leukemia virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itgb2 ENSMUSG00000000290 0.570836132666921 0.570836132666921 0.127987847862014 0.191981771793021 0.0579478375430677 0.173843512629203
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Tbp ENSMUSG00000014767 0.45596561163947 0.643359829732651 0.096425230538547 0.289275691615641 0.643359829732651 0.643359829732651
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
E2f3 ENSMUSG00000016477 0.926658283600152 1 0.643853282854191 1 1 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Nfyb ENSMUSG00000020248 0.78180291566155 0.92589277149125 0.577259514257969 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Ets2 ENSMUSG00000022895 0.577259514257969 0.577259514257969 0.0964252305385473 0.289275691615642 0.454942951775342 0.577259514257969
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
E2f1 ENSMUSG00000027490 0.455625354715449 0.965039744598977 1 1 0.643359829732651 0.965039744598977
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Cdkn2c ENSMUSG00000028551 0.643359829732651 0.643359829732651 0.177153312234059 0.265729968351089 0.0588232673880151 0.176469802164045
Calr4 ENSMUSG00000028558 0.348008842235184 0.522013263352777 0.148115998140415 0.444347994421246 0.926658283600152 0.926658283600152
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Egr1 ENSMUSG00000038418 0.120545895661628 0.323235417174495 0.21549027811633 0.323235417174495 0.926658283600152 0.926658283600152
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Atf4 ENSMUSG00000042406 1 1 0.216214347033995 0.648643041101984 0.513026869856283 0.769540304784424
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
H2-T23 ENSMUSG00000067212 0.400265374208515 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345 0.514934023620345
H2-Eb2 ENSMUSG00000067341 0.318952624781367 0.318952624781367 0.0620950549395545 0.186285164818663 0.318952624781367 0.318952624781367
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Glycosaminoglycan biosynthesis - keratan sulfate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
Chst2 ENSMUSG00000033350 0.5155648232968 0.926003599371282 0.926003599371282 0.926003599371282 0.781170242226513 0.926003599371282
B3gnt7 ENSMUSG00000079445 0.398108175780842 0.963550128145642 1 1 0.642366752097095 0.963550128145642

Wnt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt9a ENSMUSG00000000126 0.398829756175299 0.575536202757516 0.575536202757516 0.575536202757516 0.346527959006435 0.575536202757516
Ppard ENSMUSG00000002250 1 1 0.0334587898203824 0.100376369461147 0.254414773803597 0.381622160705395
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Nlk ENSMUSG00000017376 0.578396848531894 0.712057867818062 0.712057867818062 0.712057867818062 0.45596561163947 0.712057867818062
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Ppp3cb ENSMUSG00000021816 0.782117202022501 0.926550375688041 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Ctnnd2 ENSMUSG00000022240 1 1 0.926550375688041 1 0.853480389728993 1
Wnt7b ENSMUSG00000022382 1 1 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026
Csnk1e ENSMUSG00000022433 0.180293335960318 0.540880007880955 0.400265374208515 0.600398061312773 0.640355507848752 0.640355507848752
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Wnt10a ENSMUSG00000026167 0.454942951775341 0.711034989117171 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171
Nfatc2 ENSMUSG00000027544 0.643853282854191 0.643853282854191 0.179945789077372 0.539837367232115 0.577829325134931 0.643853282854191
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Invs ENSMUSG00000028344 0.926658283600152 0.926658283600152 0.455625354715449 0.926658283600152 0.926441990075769 0.926658283600152
Prickle2 ENSMUSG00000030020 0.400265374208515 0.577829325134931 0.577829325134931 0.577829325134931 0.454600801949285 0.577829325134931
Ruvbl1 ENSMUSG00000030079 0.509144723230069 0.509144723230069 0.205174703261494 0.307762054892242 0.144157978128026 0.307762054892242
Gpc4 ENSMUSG00000031119 0.120850531362929 0.362551594088788 1 1 0.577259514257969 0.865889271386954
Nkd1 ENSMUSG00000031661 0.399548817627027 0.599323226440541 0.926658283600152 0.926658283600152 0.300095920620218 0.599323226440541
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Prickle1 ENSMUSG00000036158 0.782117202022501 0.782117202022501 0.711854160331342 0.782117202022501 0.78180291566155 0.782117202022501
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Measles

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Bcl2l1 ENSMUSG00000007659 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.299349060054895 0.575536202757516
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Tnfaip3 ENSMUSG00000019850 0.78180291566155 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Cblb ENSMUSG00000022637 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.148115998140416 0.444347994421247
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Fcgr2b ENSMUSG00000026656 0.643853282854191 0.643853282854191 0.178901132102685 0.536703396308054 0.578396848531894 0.643853282854191
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Jak1 ENSMUSG00000028530 0.5155648232968 0.640861491578951 0.640861491578951 0.640861491578951 0.255530331334266 0.640861491578951
Eif2ak1 ENSMUSG00000029613 0.706831781264721 0.779888212132595 0.779888212132595 0.779888212132595 0.638824656785692 0.779888212132595
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Tradd ENSMUSG00000031887 0.17924968721805 0.17924968721805 0.00468160475316412 0.00702240712974618 0.000157492167861667 0.000472476503585
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Cd209c ENSMUSG00000040165 0.712057867818062 0.712057867818062 0.643853282854191 0.712057867818062 0.45596561163947 0.712057867818062
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Adherens junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Pvrl4 ENSMUSG00000006411 0.710416009055326 0.710416009055326 0.346527959006435 0.683948417459205 0.45596561163947 0.683948417459205
Nlk ENSMUSG00000017376 0.578396848531894 0.712057867818062 0.712057867818062 0.712057867818062 0.45596561163947 0.712057867818062
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Ptprj ENSMUSG00000025314 0.711240436189781 0.711240436189781 0.643853282854191 0.711240436189781 0.577259514257969 0.711240436189781
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Tjp1 ENSMUSG00000030516 0.853372965654504 0.853372965654504 0.0443599545252853 0.133079863575856 0.141500034183268 0.212250051274902
Was ENSMUSG00000031165 0.215127611919162 0.645382835757485 0.926604389137101 0.926604389137101 0.514617706526787 0.77192655979018
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Ctnnd1 ENSMUSG00000034101 0.45596561163947 0.683948417459205 0.926003599371282 0.926003599371282 0.295581119060361 0.683948417459205
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Pvrl2 ENSMUSG00000062300 0.853694531487825 0.853694531487825 0.643359829732651 0.853694531487825 0.214037080764326 0.642111242292977
Ctnna2 ENSMUSG00000063063 0.400265374208515 0.400265374208515 0.120545895661628 0.361637686984883 0.397384062266614 0.400265374208515

Retrograde endocannabinoid signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabrg1 ENSMUSG00000001260 0.640355507848752 0.711650020253571 0.57466664340579 0.711650020253571 0.711650020253571 0.711650020253571
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Ndufa12 ENSMUSG00000020022 0.214764523938594 0.644293571815782 0.454942951775341 0.682414427663012 0.92622377157404 0.92622377157404
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Abhd6 ENSMUSG00000025277 0.642366752097095 0.711034989117171 0.575824878403157 0.711034989117171 0.711034989117171 0.711034989117171
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Mgll ENSMUSG00000033174 0.399548817627028 0.7733472349452 0.926333123228344 0.926333123228344 0.5155648232968 0.7733472349452
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Daglb ENSMUSG00000039206 0.120545895661628 0.361637686984883 0.706831781264721 0.706831781264721 0.642366752097095 0.706831781264721
Rims1 ENSMUSG00000041670 0.781170242226513 1 1 1 0.853801250889739 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Napepld ENSMUSG00000044968 0.177153312234059 0.531459936702177 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Fluid shear stress and atherosclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pdgfb ENSMUSG00000000489 0.852832278580641 0.852832278580641 0.57466664340579 0.852832278580641 0.513665062682276 0.852832278580641
Keap1 ENSMUSG00000003308 0.342405296020881 0.600398061312773 0.642366752097095 0.642366752097095 0.400265374208515 0.600398061312773
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Sqstm1 ENSMUSG00000015837 1 1 0.852940894477647 1 0.216214347033995 0.648643041101984
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Nppc ENSMUSG00000026241 0.17924968721805 0.516994836448954 0.926550375688041 0.926550375688041 0.344663224299303 0.516994836448954
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Acvr2a ENSMUSG00000052155 0.148115998140415 0.148115998140415 0.0741204440774082 0.148115998140415 0.113498953177704 0.148115998140415
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Klf2 ENSMUSG00000055148 0.214764523938594 0.644293571815781 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739

Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B4galt7 ENSMUSG00000021504 0.455625354715448 0.455625354715448 0.146800541856249 0.323235417174495 0.21549027811633 0.323235417174495
Xylt1 ENSMUSG00000030657 0.643853282854191 0.643853282854191 0.299349060054895 0.643853282854191 0.577259514257969 0.643853282854191
Chpf ENSMUSG00000032997 0.78148726569172 0.853694531487825 0.853694531487825 0.853694531487825 0.455625354715449 0.853694531487825
Chst12 ENSMUSG00000036599 0.643853282854191 0.965779924281287 1 1 0.514934023620345 0.965779924281287
Chst7 ENSMUSG00000037347 0.254414773803597 0.381622160705395 0.395928178642446 0.395928178642446 0.120545895661628 0.361637686984883
B3gat3 ENSMUSG00000071649 0.255901190956604 0.383851786434906 0.575536202757516 0.575536202757516 0.252920381501206 0.383851786434906

Endometrial cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Apc2 ENSMUSG00000020135 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948 0.348008842235184 0.598244634262948
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Gadd45a ENSMUSG00000036390 0.400265374208515 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Ctnna2 ENSMUSG00000063063 0.400265374208515 0.400265374208515 0.120545895661628 0.361637686984883 0.397384062266614 0.400265374208515
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Adcy2 ENSMUSG00000021536 0.926441990075769 0.926441990075769 0.782117202022501 0.926441990075769 0.300095920620218 0.900287761860654
Itgb8 ENSMUSG00000025321 0.454600801949285 0.578396848531894 0.578396848531894 0.578396848531894 0.454600801949285 0.578396848531894
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Tnnt2 ENSMUSG00000026414 0.643359829732651 0.643359829732651 0.347639524025037 0.643359829732651 0.576973746230334 0.643359829732651
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Sgcb ENSMUSG00000029156 0.926333123228344 0.926333123228344 0.711854160331342 0.926333123228344 0.454600801949285 0.926333123228344
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Cacng8 ENSMUSG00000053395 0.852504981253341 0.92589277149125 0.456305241393103 0.92589277149125 0.92589277149125 0.92589277149125
Myl3 ENSMUSG00000059741 0.00958959630219563 0.0287687889065869 0.146141353215796 0.219212029823694 0.296339225025931 0.296339225025931
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155

Proteoglycans in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt9a ENSMUSG00000000126 0.398829756175299 0.575536202757516 0.575536202757516 0.575536202757516 0.346527959006435 0.575536202757516
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Cd44 ENSMUSG00000005087 0.00442026986621115 0.0132608095986335 0.00892508641180901 0.0133876296177135 0.0953125666339398 0.0953125666339398
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Ppp1r12c ENSMUSG00000019254 0.0432318933800775 0.129695680140232 0.509144723230069 0.509144723230069 0.105759219123976 0.158638828685963
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Ddx5 ENSMUSG00000020719 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334 0.514934023620345 0.576973746230334
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Plau ENSMUSG00000021822 0.17504482474598 0.262567237118971 0.566593564630738 0.566593564630738 0.0969812105731562 0.262567237118971
Wnt7b ENSMUSG00000022382 1 1 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Hcls1 ENSMUSG00000022831 0.0936419271039908 0.280925781311972 0.779888212132595 0.779888212132595 0.711650020253571 0.779888212132595
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Wnt10a ENSMUSG00000026167 0.454942951775341 0.711034989117171 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pak1 ENSMUSG00000030774 0.926333123228344 0.926333123228344 0.852504981253341 0.926333123228344 0.853372965654504 0.926333123228344
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

mTOR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt9a ENSMUSG00000000126 0.398829756175299 0.575536202757516 0.575536202757516 0.575536202757516 0.346527959006435 0.575536202757516
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ulk2 ENSMUSG00000004798 0.21549027811633 0.576973746230334 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Igf1r ENSMUSG00000005533 0.255530331334266 0.348008842235184 0.348008842235184 0.348008842235184 0.21549027811633 0.348008842235184
Atp6v1b2 ENSMUSG00000006273 0.514934023620345 0.711854160331342 0.348008842235184 0.711854160331342 0.711854160331342 0.711854160331342
Slc3a2 ENSMUSG00000010095 0.643359829732651 0.643359829732651 0.454942951775341 0.643359829732651 0.643359829732651 0.643359829732651
Gatsl2 ENSMUSG00000015944 0.300095920620218 0.450143880930327 1 1 0.255901190956604 0.450143880930327
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Wnt7b ENSMUSG00000022382 1 1 0.578113371816017 0.867170057724026 0.577259514257969 0.867170057724026
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Rps6kb2 ENSMUSG00000024830 0.578113371816017 0.578113371816017 0.298599969973533 0.447899954960299 0.216214347033995 0.447899954960299
Wnt10a ENSMUSG00000026167 0.454942951775341 0.711034989117171 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171
Rragc ENSMUSG00000028646 0.453225835454266 0.453225835454266 0.0331400397096515 0.0994201191289544 0.346899083932133 0.453225835454266
Ulk1 ENSMUSG00000029512 0.298599969973533 0.895799909920599 0.926658283600152 0.926658283600152 0.643359829732651 0.926658283600152
Eif4ebp1 ENSMUSG00000031490 0.447621891168214 0.671432836752321 0.300095920620218 0.671432836752321 1 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Wnt4 ENSMUSG00000036856 1 1 0.578113371816017 0.867170057724026 0.255901190956604 0.767703572869812
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Slc7a5 ENSMUSG00000040010 0.577829325134931 0.643359829732651 0.643359829732651 0.643359829732651 0.058823267388015 0.176469802164045
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Rnf152 ENSMUSG00000047496 0.398108175780842 0.597162263671263 0.0334587898203823 0.100376369461147 0.9255572759333 0.9255572759333
Strada ENSMUSG00000069631 0.643853282854191 0.643853282854191 0.0753654386865988 0.226096316059796 0.5155648232968 0.643853282854191
Rraga ENSMUSG00000070934 0.566593564630738 0.566593564630738 0.291756209988535 0.521459286037555 0.347639524025037 0.521459286037555

Prolactin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Socs7 ENSMUSG00000038485 0.711854160331342 0.926333123228344 0.926333123228344 0.926333123228344 0.5155648232968 0.926333123228344
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Ccnd1 ENSMUSG00000070348 0.853480389728993 0.853480389728993 0.780851835278818 0.853480389728993 0.398108175780842 0.853480389728993

Chagas disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fasl ENSMUSG00000000817 0.455284468727762 0.964296486337094 1 1 0.642864324224729 0.964296486337094
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Ifngr2 ENSMUSG00000022965 0.398108175780842 0.577259514257969 0.0964252305385473 0.289275691615642 0.577259514257969 0.577259514257969
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Calr4 ENSMUSG00000028558 0.348008842235184 0.522013263352777 0.148115998140415 0.444347994421246 0.926658283600152 0.926658283600152
Ppp2r2c ENSMUSG00000029120 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk10 ENSMUSG00000046709 0.642366752097095 0.711854160331342 0.643853282854191 0.711854160331342 0.711854160331342 0.711854160331342
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127

Phosphatidylinositol signaling system

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Pip4k2b ENSMUSG00000018547 0.926441990075769 1 1 1 0.45596561163947 1
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Synj1 ENSMUSG00000022973 0.0733738589968007 0.220121576990402 0.399548817627028 0.399548817627028 0.254787123615605 0.382180685423408
Pip4k2c ENSMUSG00000025417 0.5155648232968 0.642366752097095 0.642366752097095 0.642366752097095 0.577829325134931 0.642366752097095
Inpp4a ENSMUSG00000026113 0.926550375688041 0.926550375688041 0.118714930081337 0.35614479024401 0.455625354715449 0.683438032073173
Pi4k2b ENSMUSG00000029186 0.120545895661627 0.270440003940477 0.180293335960318 0.270440003940477 0.853907737111068 0.853907737111068
Cds1 ENSMUSG00000029330 0.92622377157404 1 1 1 0.578113371816017 1
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Pi4kb ENSMUSG00000038861 0.575536202757516 0.863304304136274 1 1 0.291756209988535 0.863304304136274
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Ppip5k2 ENSMUSG00000040648 0.576973746230334 0.865460619345501 0.926003599371281 0.926003599371281 0.254414773803597 0.763244321410791
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Col5a3 ENSMUSG00000004098 0.853372965654504 0.853372965654504 0.782117202022501 0.853372965654504 0.178901132102685 0.536703396308054
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Git1 ENSMUSG00000011877 0.853480389728993 0.853480389728993 0.345037391052887 0.770497594023414 0.513665062682276 0.770497594023414
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Col6a2 ENSMUSG00000020241 0.576112968612194 0.641867098978198 0.17924968721805 0.537749061654149 0.641867098978198 0.641867098978198
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Sema4d ENSMUSG00000021451 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516 0.120545895661628 0.361637686984883
Pdlim7 ENSMUSG00000021493 0.254787123615605 0.254787123615605 0.178901132102685 0.254787123615605 0.118409250205154 0.254787123615605
Gfra2 ENSMUSG00000022103 0.926550375688041 0.926550375688041 0.781170242226513 0.926550375688041 0.346527959006435 0.926550375688041
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vldlr ENSMUSG00000024924 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636 0.454600801949285 0.511742979522636
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Unc5a ENSMUSG00000025876 0.578113371816017 0.643359829732651 0.577259514257969 0.643359829732651 0.643359829732651 0.643359829732651
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Epha4 ENSMUSG00000026235 0.577829325134931 0.866743987702397 0.348008842235184 0.866743987702397 0.926550375688041 0.926550375688041
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Nfasc ENSMUSG00000026442 0.853694531487825 0.853694531487825 0.577829325134931 0.853694531487825 0.45596561163947 0.853694531487825
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Ptpra ENSMUSG00000027303 0.513665062682276 0.770497594023414 1 1 0.453570536021945 0.770497594023414
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Ephb2 ENSMUSG00000028664 0.78180291566155 0.78180291566155 0.297095062262362 0.445642593393543 0.216214347033995 0.445642593393543
Lypla2 ENSMUSG00000028670 1 1 0.711650020253571 1 0.926333123228344 1
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Plxna4 ENSMUSG00000029765 0.216214347033995 0.449023590082343 0.78180291566155 0.78180291566155 0.299349060054895 0.449023590082343
Plxna1 ENSMUSG00000030084 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.294820734456232 0.642864324224729
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Siah2 ENSMUSG00000036432 0.926003599371281 1 0.77858338846904 1 1 1
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Sema7a ENSMUSG00000038264 0.400265374208515 0.867170057724026 0.926441990075769 0.926441990075769 0.578113371816017 0.867170057724026
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Cdk5r1 ENSMUSG00000048895 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152 0.782117202022501 0.926658283600152
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Dscam ENSMUSG00000050272 0.578113371816017 0.578113371816017 0.400265374208515 0.578113371816017 0.179945789077372 0.539837367232116
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Rnd1 ENSMUSG00000054855 0.643853282854191 0.710208797518812 0.710208797518812 0.710208797518812 0.0964252305385472 0.289275691615642
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Nck2 ENSMUSG00000066877 1 1 0.513665062682276 0.770497594023414 0.399548817627028 0.770497594023414
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Nervous system development

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Col5a3 ENSMUSG00000004098 0.853372965654504 0.853372965654504 0.782117202022501 0.853372965654504 0.178901132102685 0.536703396308054
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Git1 ENSMUSG00000011877 0.853480389728993 0.853480389728993 0.345037391052887 0.770497594023414 0.513665062682276 0.770497594023414
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Col6a2 ENSMUSG00000020241 0.576112968612194 0.641867098978198 0.17924968721805 0.537749061654149 0.641867098978198 0.641867098978198
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Sema4d ENSMUSG00000021451 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516 0.120545895661628 0.361637686984883
Pdlim7 ENSMUSG00000021493 0.254787123615605 0.254787123615605 0.178901132102685 0.254787123615605 0.118409250205154 0.254787123615605
Gfra2 ENSMUSG00000022103 0.926550375688041 0.926550375688041 0.781170242226513 0.926550375688041 0.346527959006435 0.926550375688041
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Mapk12 ENSMUSG00000022610 0.641867098978198 0.641867098978198 0.0756145297453647 0.226843589236094 0.514934023620345 0.641867098978198
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Vldlr ENSMUSG00000024924 0.254787123615605 0.511742979522636 0.511742979522636 0.511742979522636 0.454600801949285 0.511742979522636
Itgb1 ENSMUSG00000025809 0.254414773803597 0.381622160705395 0.253294730253594 0.381622160705395 0.926441990075769 0.926441990075769
Unc5a ENSMUSG00000025876 0.578113371816017 0.643359829732651 0.577259514257969 0.643359829732651 0.643359829732651 0.643359829732651
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Epha4 ENSMUSG00000026235 0.577829325134931 0.866743987702397 0.348008842235184 0.866743987702397 0.926550375688041 0.926550375688041
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Nfasc ENSMUSG00000026442 0.853694531487825 0.853694531487825 0.577829325134931 0.853694531487825 0.45596561163947 0.853694531487825
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Ptpra ENSMUSG00000027303 0.513665062682276 0.770497594023414 1 1 0.453570536021945 0.770497594023414
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Efna4 ENSMUSG00000028040 0.853801250889739 0.853801250889739 0.577829325134931 0.853801250889739 0.577544706586058 0.853801250889739
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Ephb2 ENSMUSG00000028664 0.78180291566155 0.78180291566155 0.297095062262362 0.445642593393543 0.216214347033995 0.445642593393543
Lypla2 ENSMUSG00000028670 1 1 0.711650020253571 1 0.926333123228344 1
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Plxna4 ENSMUSG00000029765 0.216214347033995 0.449023590082343 0.78180291566155 0.78180291566155 0.299349060054895 0.449023590082343
Plxna1 ENSMUSG00000030084 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.294820734456232 0.642864324224729
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Siah2 ENSMUSG00000036432 0.926003599371281 1 0.77858338846904 1 1 1
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Sema7a ENSMUSG00000038264 0.400265374208515 0.867170057724026 0.926441990075769 0.926441990075769 0.578113371816017 0.867170057724026
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Cdk5r1 ENSMUSG00000048895 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152 0.782117202022501 0.926658283600152
Efna5 ENSMUSG00000048915 0.179249687218049 0.269918683616058 0.643853282854191 0.643853282854191 0.179945789077372 0.269918683616058
Dscam ENSMUSG00000050272 0.578113371816017 0.578113371816017 0.400265374208515 0.578113371816017 0.179945789077372 0.539837367232116
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Rnd1 ENSMUSG00000054855 0.643853282854191 0.710208797518812 0.710208797518812 0.710208797518812 0.0964252305385472 0.289275691615642
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Nck2 ENSMUSG00000066877 1 1 0.513665062682276 0.770497594023414 0.399548817627028 0.770497594023414
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Neuronal System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Dlgap1 ENSMUSG00000003279 0.711240436189781 0.853694531487825 0.255901190956604 0.767703572869812 0.853694531487825 0.853694531487825
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Ptprs ENSMUSG00000013236 0.852940894477647 0.926003599371282 0.926003599371282 0.926003599371282 0.569937449249116 0.926003599371282
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Camkk1 ENSMUSG00000020785 0.576973746230334 0.710416009055326 0.710416009055326 0.710416009055326 0.513026869856283 0.710416009055326
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nrxn1 ENSMUSG00000024109 0.255530331334266 0.766590994002797 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Apba1 ENSMUSG00000024897 0.514934023620345 0.514934023620345 0.397384062266614 0.514934023620345 0.297848640636702 0.514934023620345
Maoa ENSMUSG00000025037 1 1 0.705968934865368 1 0.7802108304765 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Chrna4 ENSMUSG00000027577 0.781170242226513 0.852940894477647 0.852940894477647 0.852940894477647 0.513665062682276 0.852940894477647
Kcnq4 ENSMUSG00000028631 0.256271555563966 0.768814666691898 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Lrfn1 ENSMUSG00000030600 0.711240436189781 0.711240436189781 0.454600801949285 0.681901202923927 0.453225835454266 0.681901202923927
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Shank2 ENSMUSG00000037541 0.254414773803597 0.763244321410791 0.509798138101151 0.764697207151727 0.92589277149125 0.92589277149125
Kcnh3 ENSMUSG00000037579 0.177153312234059 0.436476423112208 0.290984282074805 0.436476423112208 0.782117202022501 0.782117202022501
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Kcna6 ENSMUSG00000038077 0.926333123228344 0.926333123228344 0.254787123615606 0.599323226440542 0.399548817627028 0.599323226440542
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Lrfn2 ENSMUSG00000040490 0.781170242226513 0.853480389728993 0.853480389728993 0.853480389728993 0.344663224299303 0.853480389728993
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcng4 ENSMUSG00000045246 0.398829756175298 0.398829756175298 0.295581119060361 0.398829756175298 0.395196379647461 0.398829756175298
Kcna3 ENSMUSG00000047959 0.120545895661628 0.361637686984883 0.398829756175299 0.398829756175299 0.347639524025037 0.398829756175299
Kcnk3 ENSMUSG00000049265 0.578396848531894 0.578396848531894 0.513026869856283 0.578396848531894 0.514934023620345 0.578396848531894
Kcnb1 ENSMUSG00000050556 0.398108175780842 0.578113371816017 0.346899083932133 0.578113371816017 0.578113371816017 0.578113371816017
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Nlgn2 ENSMUSG00000051790 0.781170242226513 0.852504981253341 0.852504981253341 0.852504981253341 0.300095920620218 0.852504981253341
Kcnmb4 ENSMUSG00000054934 1 1 0.398108175780842 0.866743987702397 0.577829325134931 0.866743987702397
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642
Tspan7 ENSMUSG00000058254 0.255530331334266 0.683438032073173 0.926003599371281 0.926003599371281 0.455625354715448 0.683438032073173
Panx2 ENSMUSG00000058441 1 1 0.712057867818062 1 0.399548817627028 1
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Ntrk3 ENSMUSG00000059146 0.925444427431699 0.925444427431699 0.925331064166297 0.925444427431699 0.345037391052887 0.925444427431699
Flot1 ENSMUSG00000059714 0.853907737111068 0.853907737111068 0.300095920620218 0.450143880930327 0.299349060054895 0.450143880930327
Kcng2 ENSMUSG00000059852 0.395928178642446 0.395928178642446 0.242620429494012 0.381622160705395 0.254414773803597 0.381622160705395
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Ion homeostasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sri ENSMUSG00000003161 0.707899741868332 0.707899741868332 0.178901132102685 0.536703396308054 0.578396848531894 0.707899741868332
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Fkbp1b ENSMUSG00000020635 0.926550375688041 0.926550375688041 0.926003599371281 0.926550375688041 0.514934023620345 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Ahcyl1 ENSMUSG00000027893 0.853801250889739 0.853801250889739 0.853372965654504 0.853801250889739 0.711240436189781 0.853801250889739
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Fxyd7 ENSMUSG00000036578 0.5155648232968 0.5155648232968 0.514300775319626 0.5155648232968 0.514934023620345 0.5155648232968
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Fxyd6 ENSMUSG00000066705 0.926550375688041 0.926550375688041 0.147458757705094 0.222173997210623 0.148115998140416 0.222173997210623
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Transmission across Chemical Synapses

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Camkk1 ENSMUSG00000020785 0.576973746230334 0.710416009055326 0.710416009055326 0.710416009055326 0.513026869856283 0.710416009055326
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Apba1 ENSMUSG00000024897 0.514934023620345 0.514934023620345 0.397384062266614 0.514934023620345 0.297848640636702 0.514934023620345
Maoa ENSMUSG00000025037 1 1 0.705968934865368 1 0.7802108304765 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Chrna4 ENSMUSG00000027577 0.781170242226513 0.852940894477647 0.852940894477647 0.852940894477647 0.513665062682276 0.852940894477647
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642
Tspan7 ENSMUSG00000058254 0.255530331334266 0.683438032073173 0.926003599371281 0.926003599371281 0.455625354715448 0.683438032073173
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Cardiac conduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sri ENSMUSG00000003161 0.707899741868332 0.707899741868332 0.178901132102685 0.536703396308054 0.578396848531894 0.707899741868332
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Scn1b ENSMUSG00000019194 0.45596561163947 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Fkbp1b ENSMUSG00000020635 0.926550375688041 0.926550375688041 0.926003599371281 0.926550375688041 0.514934023620345 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Nppc ENSMUSG00000026241 0.17924968721805 0.516994836448954 0.926550375688041 0.926550375688041 0.344663224299303 0.516994836448954
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Ahcyl1 ENSMUSG00000027893 0.853801250889739 0.853801250889739 0.853372965654504 0.853801250889739 0.711240436189781 0.853801250889739
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Fgf13 ENSMUSG00000031137 0.711034989117171 0.711034989117171 0.578396848531894 0.711034989117171 0.399548817627028 0.711034989117171
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Fxyd7 ENSMUSG00000036578 0.5155648232968 0.5155648232968 0.514300775319626 0.5155648232968 0.514934023620345 0.5155648232968
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Kcne4 ENSMUSG00000047330 0.578113371816017 1 0.92622377157404 1 1 1
Kcnk3 ENSMUSG00000049265 0.578396848531894 0.578396848531894 0.513026869856283 0.578396848531894 0.514934023620345 0.578396848531894
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Fxyd6 ENSMUSG00000066705 0.926550375688041 0.926550375688041 0.147458757705094 0.222173997210623 0.148115998140416 0.222173997210623
Scn2b ENSMUSG00000070304 0.642366752097095 0.926003599371282 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Inwardly rectifying K+ channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Muscle contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sri ENSMUSG00000003161 0.707899741868332 0.707899741868332 0.178901132102685 0.536703396308054 0.578396848531894 0.707899741868332
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Tcap ENSMUSG00000007877 1 1 0.853372965654504 1 0.78180291566155 1
Scn1b ENSMUSG00000019194 0.45596561163947 0.578396848531894 0.577259514257969 0.578396848531894 0.578396848531894 0.578396848531894
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Fkbp1b ENSMUSG00000020635 0.926550375688041 0.926550375688041 0.926003599371281 0.926550375688041 0.514934023620345 0.926550375688041
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Nppc ENSMUSG00000026241 0.17924968721805 0.516994836448954 0.926550375688041 0.926550375688041 0.344663224299303 0.516994836448954
Tnnt2 ENSMUSG00000026414 0.643359829732651 0.643359829732651 0.347639524025037 0.643359829732651 0.576973746230334 0.643359829732651
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Ahcyl1 ENSMUSG00000027893 0.853801250889739 0.853801250889739 0.853372965654504 0.853801250889739 0.711240436189781 0.853801250889739
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Ryr1 ENSMUSG00000030592 0.252545530864481 0.378818296296721 0.853801250889739 0.853801250889739 0.174692232033629 0.378818296296721
Fgf13 ENSMUSG00000031137 0.711034989117171 0.711034989117171 0.578396848531894 0.711034989117171 0.399548817627028 0.711034989117171
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Acta1 ENSMUSG00000031972 0.0447373296833729 0.134211989050119 0.505169133438821 0.706831781264721 0.706831781264721 0.706831781264721
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Dysf ENSMUSG00000033788 0.347639524025037 0.926550375688041 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Fxyd7 ENSMUSG00000036578 0.5155648232968 0.5155648232968 0.514300775319626 0.5155648232968 0.514934023620345 0.5155648232968
Myl6b ENSMUSG00000039824 1 1 0.299349060054895 0.449023590082343 0.178901132102685 0.449023590082343
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Kcne4 ENSMUSG00000047330 0.578113371816017 1 0.92622377157404 1 1 1
Kcnk3 ENSMUSG00000049265 0.578396848531894 0.578396848531894 0.513026869856283 0.578396848531894 0.514934023620345 0.578396848531894
Ryr3 ENSMUSG00000057378 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299 0.214037080764326 0.398829756175299
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Myl3 ENSMUSG00000059741 0.00958959630219563 0.0287687889065869 0.146141353215796 0.219212029823694 0.296339225025931 0.296339225025931
Tnnt1 ENSMUSG00000064179 0.578113371816017 0.578113371816017 0.513026869856283 0.578113371816017 0.0303111090728678 0.0909333272186035
Fxyd6 ENSMUSG00000066705 0.926550375688041 0.926550375688041 0.147458757705094 0.222173997210623 0.148115998140416 0.222173997210623
Scn2b ENSMUSG00000070304 0.642366752097095 0.926003599371282 0.256271555563966 0.768814666691898 0.926003599371282 0.926003599371282
Cacng6 ENSMUSG00000078815 0.451840588205061 0.677760882307592 0.147458757705094 0.442376273115283 0.78180291566155 0.78180291566155
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Membrane Trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Epn2 ENSMUSG00000001036 0.454600801949285 0.853694531487825 0.853694531487825 0.853694531487825 0.643359829732651 0.853694531487825
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Ap4e1 ENSMUSG00000001998 0.293293089483362 0.578113371816017 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Sh3gl1 ENSMUSG00000003200 0.926003599371282 0.926003599371282 0.643853282854191 0.926003599371282 0.345410946355104 0.926003599371282
Cyth2 ENSMUSG00000003269 0.853801250889739 1 0.45596561163947 1 1 1
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
D130043K22Rik ENSMUSG00000006711 0.578396848531894 0.867595272797842 0.179249687218049 0.537749061654148 1 1
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Ankrd28 ENSMUSG00000014496 0.781645261743309 0.781645261743309 0.297472133192261 0.76322556548407 0.508817043656047 0.76322556548407
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Vps53 ENSMUSG00000017288 0.640355507848752 0.85117361048289 0.85117361048289 0.85117361048289 0.346527959006435 0.85117361048289
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Cops3 ENSMUSG00000019373 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Vps54 ENSMUSG00000020128 0.120850531362929 0.29252580908486 0.29252580908486 0.29252580908486 0.255530331334266 0.29252580908486
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Kif3c ENSMUSG00000020668 0.781170242226513 0.781170242226513 0.708534948098331 0.781170242226513 0.345410946355104 0.781170242226513
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Amph ENSMUSG00000021314 0.853694531487825 0.853694531487825 0.779238691542963 0.853694531487825 0.575536202757516 0.853694531487825
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Racgap1 ENSMUSG00000023015 0.853801250889739 0.853801250889739 0.344663224299303 0.7733472349452 0.5155648232968 0.7733472349452
Fth1 ENSMUSG00000024661 0.642366752097095 1 1 1 0.851954599472143 1
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Cnih2 ENSMUSG00000024873 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739 0.643359829732651 0.853801250889739
Vti1a ENSMUSG00000024983 0.926003599371282 0.926003599371282 0.576112968612194 0.864169452918291 0.300095920620218 0.864169452918291
Rabgef1 ENSMUSG00000025340 0.92589277149125 0.92589277149125 0.576973746230334 0.92589277149125 0.7802108304765 0.92589277149125
Chmp6 ENSMUSG00000025371 0.178901132102685 0.514934023620344 0.514934023620344 0.514934023620344 0.348008842235184 0.514934023620344
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Stx6 ENSMUSG00000026470 0.0969812105731563 0.290943631719469 0.852065168704833 0.852065168704833 0.216214347033995 0.324321520550992
Cnih3 ENSMUSG00000026514 0.643359829732651 0.711854160331342 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342
Golga1 ENSMUSG00000026754 0.514934023620345 0.772401035430517 0.926658283600152 0.926658283600152 0.45596561163947 0.772401035430517
Kif3b ENSMUSG00000027475 0.400265374208515 0.853694531487825 0.853694531487825 0.853694531487825 0.578113371816017 0.853694531487825
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Dnajc6 ENSMUSG00000028528 0.577829325134931 0.866743987702397 1 1 0.299349060054895 0.866743987702397
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Gcc1 ENSMUSG00000029708 0.642366752097095 1 1 1 0.853801250889739 1
Tjp1 ENSMUSG00000030516 0.853372965654504 0.853372965654504 0.0443599545252853 0.133079863575856 0.141500034183268 0.212250051274902
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Rab6b ENSMUSG00000032549 0.853694531487825 1 1 1 0.5155648232968 1
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Epgn ENSMUSG00000035020 0.778088064569037 0.778088064569037 0.337049057953584 0.666591427564543 0.444394285043028 0.666591427564543
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Epn1 ENSMUSG00000035203 0.578113371816017 0.926441990075769 0.926441990075769 0.926441990075769 0.78148726569172 0.926441990075769
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Tbc1d24 ENSMUSG00000036473 0.643359829732651 0.643359829732651 0.578113371816017 0.643359829732651 0.642864324224729 0.643359829732651
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Bicd2 ENSMUSG00000037933 0.283930443883615 0.851791331650844 0.926333123228344 0.926333123228344 0.926333123228344 0.926333123228344
Chmp4b ENSMUSG00000038467 0.57466664340579 0.861999965108685 0.925217182211634 0.925217182211634 0.343537039781257 0.861999965108685
Tbc1d25 ENSMUSG00000039201 0.642864324224729 0.642864324224729 0.346899083932133 0.520348625898199 0.255901190956604 0.520348625898199
Dennd6a ENSMUSG00000040818 0.711650020253571 0.782117202022501 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Trappc9 ENSMUSG00000047921 0.514300775319626 0.771451162979439 0.852940894477647 0.852940894477647 0.342405296020881 0.771451162979439
Gja4 ENSMUSG00000050234 0.710001140920767 0.926604389137101 0.926604389137101 0.926604389137101 0.447265995733381 0.926604389137101
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Ppp6r1 ENSMUSG00000052296 0.254414773803597 0.682414427663012 1 1 0.454942951775341 0.682414427663012
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Kif1b ENSMUSG00000063077 0.514934023620345 0.7733472349452 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595
Sort1 ENSMUSG00000068747 0.853372965654504 0.853372965654504 0.577829325134931 0.853372965654504 0.642366752097095 0.853372965654504
Syt11 ENSMUSG00000068923 0.706831781264721 0.706831781264721 0.567818482366294 0.706831781264721 0.346899083932133 0.706831781264721
Rab18 ENSMUSG00000073639 0.115037265385284 0.345111796155853 0.45596561163947 0.45596561163947 0.451840588205062 0.45596561163947
Rab11b ENSMUSG00000077450 0.447265995733381 0.447265995733381 0.447265995733381 0.447265995733381 0.178901132102685 0.447265995733381
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344
Btc ENSMUSG00000082361 0.0964252305385472 0.144637845807821 0.21549027811633 0.21549027811633 0.00731348855817121 0.0219404656745136

Neurotransmitter receptors and postsynaptic signal transmission

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Camkk1 ENSMUSG00000020785 0.576973746230334 0.710416009055326 0.710416009055326 0.710416009055326 0.513026869856283 0.710416009055326
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Grin1 ENSMUSG00000026959 0.924872384323463 0.924872384323463 0.255530331334266 0.684457862089655 0.456305241393103 0.684457862089655
Chrna4 ENSMUSG00000027577 0.781170242226513 0.852940894477647 0.852940894477647 0.852940894477647 0.513665062682276 0.852940894477647
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642
Tspan7 ENSMUSG00000058254 0.255530331334266 0.683438032073173 0.926003599371281 0.926003599371281 0.455625354715448 0.683438032073173
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Signaling by Rho GTPases, Miro GTPases and RHOBTB3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Spc25 ENSMUSG00000005233 0.638051880670243 0.638051880670243 0.00555992428326542 0.0166797728497963 0.45149265530335 0.638051880670243
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Ndel1 ENSMUSG00000018736 0.146800541856249 0.440401625568746 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Gopc ENSMUSG00000019861 0.398108175780842 0.600398061312773 0.400265374208515 0.600398061312773 0.926658283600152 0.926658283600152
Rhobtb1 ENSMUSG00000019944 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.178901132102685 0.536703396308054
Ska2 ENSMUSG00000020492 0.782117202022501 0.926441990075769 0.926441990075769 0.926441990075769 0.344663224299303 0.926441990075769
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Aurkb ENSMUSG00000020897 0.92380865295296 0.92380865295296 0.00477055016690543 0.0143116505007163 0.255530331334266 0.383295497001398
Net1 ENSMUSG00000021215 0.711034989117171 0.711034989117171 0.573205482926791 0.711034989117171 0.21549027811633 0.646470834348989
Rasgrf2 ENSMUSG00000021708 0.513026869856283 0.513026869856283 0.45596561163947 0.513026869856283 0.45596561163947 0.513026869856283
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Rangap1 ENSMUSG00000022391 0.642366752097095 0.642366752097095 0.29252580908486 0.43878871362729 0.254414773803597 0.43878871362729
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Racgap1 ENSMUSG00000023015 0.853801250889739 0.853801250889739 0.344663224299303 0.7733472349452 0.5155648232968 0.7733472349452
Cenpq ENSMUSG00000023919 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Ralbp1 ENSMUSG00000024096 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.348008842235184 0.781170242226513
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Arhgdia ENSMUSG00000025132 0.641867098978198 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Ahctf1 ENSMUSG00000026491 0.0936419271039906 0.140462890655986 0.708534948098331 0.708534948098331 0.0331400397096514 0.0994201191289543
Arhgap1 ENSMUSG00000027247 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739 0.178901132102685 0.536703396308054
Mapre1 ENSMUSG00000027479 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.643853282854191 0.853694531487825
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Nudc ENSMUSG00000028851 0.343537039781257 0.442211413534162 0.442211413534162 0.442211413534162 0.299349060054895 0.442211413534162
Rhof ENSMUSG00000029449 0.926658283600152 0.926658283600152 0.252545530864481 0.521459286037555 0.347639524025037 0.521459286037555
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Cenpi ENSMUSG00000031262 0.853694531487825 0.853694531487825 0.0334587898203824 0.100376369461147 0.509144723230069 0.763717084845103
Arhgap4 ENSMUSG00000031389 0.0115535350288052 0.0346606050864155 0.0241933715424143 0.0362900573136214 0.118409250205154 0.118409250205154
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Nckipsd ENSMUSG00000032598 0.513026869856283 0.513026869856283 0.205174703261494 0.513026869856283 0.453570536021945 0.513026869856283
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Arhgap39 ENSMUSG00000033697 0.450794830295118 0.676192245442677 0.711034989117171 0.711034989117171 0.338592117141989 0.676192245442677
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Fam13a ENSMUSG00000037709 0.347269605097055 0.520904407645582 0.925948247631505 0.925948247631505 0.0109864933352154 0.0329594800056461
Arhgap18 ENSMUSG00000039031 0.399548817627028 0.770497594023414 0.926333123228344 0.926333123228344 0.513665062682276 0.770497594023414
Prex1 ENSMUSG00000039621 0.399548817627028 0.456305241393103 0.252920381501207 0.456305241393103 0.456305241393103 0.456305241393103
Rhou ENSMUSG00000039960 0.0741204440774082 0.222361332232225 0.711650020253571 0.853480389728993 0.853480389728993 0.853480389728993
Rcc2 ENSMUSG00000040945 0.641867098978198 0.78148726569172 0.78148726569172 0.78148726569172 0.578113371816017 0.78148726569172
Arhgef10l ENSMUSG00000040964 0.456305241393103 0.684457862089655 0.853372965654504 0.853372965654504 0.255901190956604 0.684457862089655
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Cenph ENSMUSG00000045273 0.643359829732651 0.782117202022501 0.642366752097095 0.782117202022501 0.782117202022501 0.782117202022501
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Arhgdig ENSMUSG00000073433 0.399548817627028 0.455625354715448 0.178901132102685 0.455625354715448 0.455625354715448 0.455625354715448
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Signaling by Rho GTPases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Spc25 ENSMUSG00000005233 0.638051880670243 0.638051880670243 0.00555992428326542 0.0166797728497963 0.45149265530335 0.638051880670243
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Rac3 ENSMUSG00000018012 0.395928178642446 0.395928178642446 0.0209878658739169 0.0629635976217506 0.246478961478169 0.369718442217254
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Ndel1 ENSMUSG00000018736 0.146800541856249 0.440401625568746 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Gopc ENSMUSG00000019861 0.398108175780842 0.600398061312773 0.400265374208515 0.600398061312773 0.926658283600152 0.926658283600152
Rhobtb1 ENSMUSG00000019944 0.57113445032749 0.575536202757516 0.575536202757516 0.575536202757516 0.178901132102685 0.536703396308054
Ska2 ENSMUSG00000020492 0.782117202022501 0.926441990075769 0.926441990075769 0.926441990075769 0.344663224299303 0.926441990075769
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Aurkb ENSMUSG00000020897 0.92380865295296 0.92380865295296 0.00477055016690543 0.0143116505007163 0.255530331334266 0.383295497001398
Net1 ENSMUSG00000021215 0.711034989117171 0.711034989117171 0.573205482926791 0.711034989117171 0.21549027811633 0.646470834348989
Rasgrf2 ENSMUSG00000021708 0.513026869856283 0.513026869856283 0.45596561163947 0.513026869856283 0.45596561163947 0.513026869856283
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Rangap1 ENSMUSG00000022391 0.642366752097095 0.642366752097095 0.29252580908486 0.43878871362729 0.254414773803597 0.43878871362729
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Racgap1 ENSMUSG00000023015 0.853801250889739 0.853801250889739 0.344663224299303 0.7733472349452 0.5155648232968 0.7733472349452
Cenpq ENSMUSG00000023919 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Ralbp1 ENSMUSG00000024096 0.642366752097095 0.781170242226513 0.781170242226513 0.781170242226513 0.348008842235184 0.781170242226513
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Arhgdia ENSMUSG00000025132 0.641867098978198 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Ahctf1 ENSMUSG00000026491 0.0936419271039906 0.140462890655986 0.708534948098331 0.708534948098331 0.0331400397096514 0.0994201191289543
Arhgap1 ENSMUSG00000027247 0.5155648232968 0.7733472349452 0.853801250889739 0.853801250889739 0.178901132102685 0.536703396308054
Mapre1 ENSMUSG00000027479 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.643853282854191 0.853694531487825
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Nudc ENSMUSG00000028851 0.343537039781257 0.442211413534162 0.442211413534162 0.442211413534162 0.299349060054895 0.442211413534162
Rhof ENSMUSG00000029449 0.926658283600152 0.926658283600152 0.252545530864481 0.521459286037555 0.347639524025037 0.521459286037555
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Cenpi ENSMUSG00000031262 0.853694531487825 0.853694531487825 0.0334587898203824 0.100376369461147 0.509144723230069 0.763717084845103
Arhgap4 ENSMUSG00000031389 0.0115535350288052 0.0346606050864155 0.0241933715424143 0.0362900573136214 0.118409250205154 0.118409250205154
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Nckipsd ENSMUSG00000032598 0.513026869856283 0.513026869856283 0.205174703261494 0.513026869856283 0.453570536021945 0.513026869856283
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Arhgap39 ENSMUSG00000033697 0.450794830295118 0.676192245442677 0.711034989117171 0.711034989117171 0.338592117141989 0.676192245442677
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Fam13a ENSMUSG00000037709 0.347269605097055 0.520904407645582 0.925948247631505 0.925948247631505 0.0109864933352154 0.0329594800056461
Arhgap18 ENSMUSG00000039031 0.399548817627028 0.770497594023414 0.926333123228344 0.926333123228344 0.513665062682276 0.770497594023414
Prex1 ENSMUSG00000039621 0.399548817627028 0.456305241393103 0.252920381501207 0.456305241393103 0.456305241393103 0.456305241393103
Rhou ENSMUSG00000039960 0.0741204440774082 0.222361332232225 0.711650020253571 0.853480389728993 0.853480389728993 0.853480389728993
Rcc2 ENSMUSG00000040945 0.641867098978198 0.78148726569172 0.78148726569172 0.78148726569172 0.578113371816017 0.78148726569172
Arhgef10l ENSMUSG00000040964 0.456305241393103 0.684457862089655 0.853372965654504 0.853372965654504 0.255901190956604 0.684457862089655
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Cenph ENSMUSG00000045273 0.643359829732651 0.782117202022501 0.642366752097095 0.782117202022501 0.782117202022501 0.782117202022501
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Arhgdig ENSMUSG00000073433 0.399548817627028 0.455625354715448 0.178901132102685 0.455625354715448 0.455625354715448 0.455625354715448
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Glycosaminoglycan metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Has1 ENSMUSG00000003665 0.711240436189781 0.711240436189781 0.299349060054895 0.599323226440542 0.399548817627028 0.599323226440542
Chp1 ENSMUSG00000014077 0.852504981253341 0.852504981253341 0.343537039781257 0.7733472349452 0.5155648232968 0.7733472349452
Ogn ENSMUSG00000021390 0.577259514257969 0.643359829732651 0.513026869856283 0.643359829732651 0.643359829732651 0.643359829732651
B4galt7 ENSMUSG00000021504 0.455625354715448 0.455625354715448 0.146800541856249 0.323235417174495 0.21549027811633 0.323235417174495
Abcc5 ENSMUSG00000022822 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041 0.78148726569172 0.926550375688041
Glb1l ENSMUSG00000026200 0.216214347033995 0.374861176998505 0.926550375688041 0.926550375688041 0.249907451332337 0.374861176998505
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Gpc4 ENSMUSG00000031119 0.120850531362929 0.362551594088788 1 1 0.577259514257969 0.865889271386954
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
Cspg5 ENSMUSG00000032482 0.297848640636702 0.521459286037555 0.78148726569172 0.78148726569172 0.347639524025037 0.521459286037555
Chpf ENSMUSG00000032997 0.78148726569172 0.853694531487825 0.853694531487825 0.853694531487825 0.455625354715449 0.853694531487825
Chst2 ENSMUSG00000033350 0.5155648232968 0.926003599371282 0.926003599371282 0.926003599371282 0.781170242226513 0.926003599371282
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Chst12 ENSMUSG00000036599 0.643853282854191 0.965779924281287 1 1 0.514934023620345 0.965779924281287
Hgsnat ENSMUSG00000037260 0.0766111619812295 0.229833485943689 0.450794830295118 0.450794830295118 0.333146020247509 0.450794830295118
Chst7 ENSMUSG00000037347 0.254414773803597 0.381622160705395 0.395928178642446 0.395928178642446 0.120545895661628 0.361637686984883
Hs3st6 ENSMUSG00000039628 0.78132892626786 0.78132892626786 0.296717426617605 0.78132892626786 0.780692109850228 0.78132892626786
Hs2st1 ENSMUSG00000040151 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155 0.180293335960318 0.540880007880955
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
Hs3st2 ENSMUSG00000046321 0.853801250889739 0.853801250889739 0.454600801949285 0.853801250889739 0.782117202022501 0.853801250889739
B3gnt1 ENSMUSG00000047379 0.7802108304765 0.7802108304765 0.707899741868332 0.7802108304765 0.299349060054895 0.7802108304765
Ndst1 ENSMUSG00000054008 0.709375484777034 0.853049270252403 0.853049270252403 0.853049270252403 0.454600801949285 0.853049270252403
B4galt6 ENSMUSG00000056124 0.058823267388015 0.176469802164045 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993
Gpc6 ENSMUSG00000058571 1 1 0.119936171404379 0.359808514213138 0.643853282854191 0.965779924281287
Ext1 ENSMUSG00000061731 0.347639524025037 0.521459286037555 0.148115998140416 0.444347994421247 0.926658283600152 0.926658283600152
B3gat3 ENSMUSG00000071649 0.255901190956604 0.383851786434906 0.575536202757516 0.575536202757516 0.252920381501206 0.383851786434906
B3gnt7 ENSMUSG00000079445 0.398108175780842 0.963550128145642 1 1 0.642366752097095 0.963550128145642

Norepinephrine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Maoa ENSMUSG00000025037 1 1 0.705968934865368 1 0.7802108304765 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041

Regulation of localization of FOXO transcription factors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Foxo6 ENSMUSG00000052135 0.246861959455465 0.740585878366394 0.514934023620345 0.772401035430517 1 1

Acetylcholine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041

Signaling by NTRKs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Plcg1 ENSMUSG00000016933 0.120545895661628 0.361637686984883 0.851061028660105 0.851061028660105 0.295581119060361 0.443371678590541
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ntrk3 ENSMUSG00000059146 0.925444427431699 0.925444427431699 0.925331064166297 0.925444427431699 0.345037391052887 0.925444427431699
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041

Platelet activation, signaling and aggregation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stxbp2 ENSMUSG00000004626 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636 0.346899083932133 0.511742979522636
Lamp2 ENSMUSG00000016534 0.0168921052924601 0.0506763158773803 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Clu ENSMUSG00000022037 0.578113371816017 0.853372965654504 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Ahsg ENSMUSG00000022868 0.397384062266614 0.397384062266614 0.347639524025037 0.397384062266614 0.299349060054895 0.397384062266614
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Pros1 ENSMUSG00000022912 0.926441990075769 0.926441990075769 0.45596561163947 0.683948417459205 0.0969812105731561 0.290943631719468
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Fermt3 ENSMUSG00000024965 0.0443599545252852 0.133079863575856 0.853372965654504 0.853372965654504 0.348008842235184 0.522013263352777
Abhd6 ENSMUSG00000025277 0.642366752097095 0.711034989117171 0.575824878403157 0.711034989117171 0.711034989117171 0.711034989117171
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cyb5r1 ENSMUSG00000026456 0.044737329683373 0.134211989050119 0.5155648232968 0.7733472349452 0.853049270252403 0.853049270252403
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Stxbp3a ENSMUSG00000027882 0.926550375688041 0.926550375688041 0.121155015244363 0.363465045733089 0.453570536021945 0.680355804032917
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Pcdh7 ENSMUSG00000029108 0.0441715176243983 0.132514552873195 0.216214347033995 0.324321520550992 0.346527959006435 0.346527959006435
Ppbp ENSMUSG00000029372 0.214037080764326 0.214037080764326 0.0449262652924809 0.134778795877443 0.0969812105731562 0.145471815859734
Pf4 ENSMUSG00000029373 0.399548817627028 0.454600801949285 0.454600801949285 0.454600801949285 0.0583853430099096 0.175156029029729
Cd9 ENSMUSG00000030342 0.0434194723707708 0.130258417112313 0.180293335960318 0.270440003940477 0.575824878403157 0.575824878403157
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Gas6 ENSMUSG00000031451 0.7802108304765 1 1 1 0.214037080764326 0.642111242292977
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Bcar1 ENSMUSG00000031955 0.346527959006435 0.643359829732651 0.511742979522636 0.643359829732651 0.643359829732651 0.643359829732651
Aplp2 ENSMUSG00000031996 0.851061028660105 0.851061028660105 0.707899741868332 0.851061028660105 0.293293089483362 0.851061028660105
Mgll ENSMUSG00000033174 0.399548817627028 0.7733472349452 0.926333123228344 0.926333123228344 0.5155648232968 0.7733472349452
Vav3 ENSMUSG00000033721 0.180293335960318 0.270440003940477 0.926550375688041 0.926550375688041 0.058823267388015 0.176469802164045
Fgb ENSMUSG00000033831 0.640861491578951 0.640861491578951 0.255901190956604 0.640861491578951 0.511742979522636 0.640861491578951
Endod1 ENSMUSG00000037419 0.513026869856283 0.513026869856283 0.511742979522636 0.513026869856283 0.148772260628989 0.446316781886968
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
F13a1 ENSMUSG00000039109 0.853801250889739 0.853801250889739 0.347639524025037 0.521459286037555 0.300095920620218 0.521459286037555
Daglb ENSMUSG00000039206 0.120545895661628 0.361637686984883 0.706831781264721 0.706831781264721 0.642366752097095 0.706831781264721
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

GABA B receptor activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Activation of GABAB receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Reduction of cytosolic Ca++ levels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sri ENSMUSG00000003161 0.707899741868332 0.707899741868332 0.178901132102685 0.536703396308054 0.578396848531894 0.707899741868332
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Slc8a2 ENSMUSG00000030376 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452 1 1
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542

Signaling by NTRK1 (TRKA)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041

Potassium Channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Kcnq4 ENSMUSG00000028631 0.256271555563966 0.768814666691898 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Abcc9 ENSMUSG00000030249 0.214764523938594 0.449023590082343 0.926550375688041 0.926550375688041 0.299349060054895 0.449023590082343
Kcnh3 ENSMUSG00000037579 0.177153312234059 0.436476423112208 0.290984282074805 0.436476423112208 0.782117202022501 0.782117202022501
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Kcna6 ENSMUSG00000038077 0.926333123228344 0.926333123228344 0.254787123615606 0.599323226440542 0.399548817627028 0.599323226440542
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcng4 ENSMUSG00000045246 0.398829756175298 0.398829756175298 0.295581119060361 0.398829756175298 0.395196379647461 0.398829756175298
Kcna3 ENSMUSG00000047959 0.120545895661628 0.361637686984883 0.398829756175299 0.398829756175299 0.347639524025037 0.398829756175299
Kcnk3 ENSMUSG00000049265 0.578396848531894 0.578396848531894 0.513026869856283 0.578396848531894 0.514934023620345 0.578396848531894
Kcnb1 ENSMUSG00000050556 0.398108175780842 0.578113371816017 0.346899083932133 0.578113371816017 0.578113371816017 0.578113371816017
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Kcnmb4 ENSMUSG00000054934 1 1 0.398108175780842 0.866743987702397 0.577829325134931 0.866743987702397
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058
Kcng2 ENSMUSG00000059852 0.395928178642446 0.395928178642446 0.242620429494012 0.381622160705395 0.254414773803597 0.381622160705395
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

Ion transport by P-type ATPases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sri ENSMUSG00000003161 0.707899741868332 0.707899741868332 0.178901132102685 0.536703396308054 0.578396848531894 0.707899741868332
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Camk2g ENSMUSG00000021820 0.853480389728993 0.853480389728993 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Atp8a2 ENSMUSG00000021983 0.398108175780842 0.597162263671263 0.926550375688041 0.926550375688041 0.346527959006435 0.597162263671263
Atp2b4 ENSMUSG00000026463 0.21549027811633 0.381622160705395 0.853480389728993 0.853480389728993 0.254414773803597 0.381622160705395
Atp2a2 ENSMUSG00000029467 0.711240436189782 1 1 1 0.255530331334266 0.766590994002797
Atp2b2 ENSMUSG00000030302 0.926441990075769 0.926441990075769 0.643359829732651 0.926441990075769 0.575824878403157 0.926441990075769
Atp2b3 ENSMUSG00000031376 0.399548817627028 0.599323226440542 0.711650020253571 0.711650020253571 0.254787123615605 0.599323226440542
Atp11a ENSMUSG00000031441 0.782117202022501 1 0.78148726569172 1 1 1
Atp1a1 ENSMUSG00000033161 0.577829325134931 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Fxyd7 ENSMUSG00000036578 0.5155648232968 0.5155648232968 0.514300775319626 0.5155648232968 0.514934023620345 0.5155648232968
Atp13a2 ENSMUSG00000036622 0.924286968561133 0.924286968561133 0.227880522358147 0.34182078353722 0.146141353215796 0.34182078353722
Atp11b ENSMUSG00000037400 0.853372965654504 0.853372965654504 0.57466664340579 0.853372965654504 0.348008842235184 0.853372965654504
Atp11c ENSMUSG00000062949 0.513665062682276 0.770497594023414 0.452880492349546 0.770497594023414 0.782117202022501 0.782117202022501
Fxyd6 ENSMUSG00000066705 0.926550375688041 0.926550375688041 0.147458757705094 0.222173997210623 0.148115998140416 0.222173997210623

COPI-mediated anterograde transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595

Activation of kainate receptors upon glutamate binding

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

G protein gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Metabolism of carbohydrates

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Has1 ENSMUSG00000003665 0.711240436189781 0.711240436189781 0.299349060054895 0.599323226440542 0.399548817627028 0.599323226440542
Tpr ENSMUSG00000006005 0.572911448356892 0.78132892626786 0.78132892626786 0.78132892626786 0.710208797518812 0.78132892626786
Pgam1 ENSMUSG00000011752 0.853372965654504 0.926333123228344 0.926333123228344 0.926333123228344 0.578113371816017 0.926333123228344
Chp1 ENSMUSG00000014077 0.852504981253341 0.852504981253341 0.343537039781257 0.7733472349452 0.5155648232968 0.7733472349452
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Gyg ENSMUSG00000019528 0.446194239410717 0.446194239410717 0.190629863394776 0.323235417174495 0.21549027811633 0.323235417174495
Pfkl ENSMUSG00000020277 0.454600801949285 0.454600801949285 0.392243127063687 0.454600801949285 0.177853449259986 0.454600801949285
Ogn ENSMUSG00000021390 0.577259514257969 0.643359829732651 0.513026869856283 0.643359829732651 0.643359829732651 0.643359829732651
B4galt7 ENSMUSG00000021504 0.455625354715448 0.455625354715448 0.146800541856249 0.323235417174495 0.21549027811633 0.323235417174495
Cryl1 ENSMUSG00000021947 0.782117202022501 1 0.78148726569172 1 1 1
Tkt ENSMUSG00000021957 0.640355507848752 0.960533261773128 1 1 0.148772260628989 0.446316781886967
Abcc5 ENSMUSG00000022822 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041 0.78148726569172 0.926550375688041
Pfkfb1 ENSMUSG00000025271 0.711034989117171 0.711034989117171 0.299349060054895 0.599323226440542 0.399548817627028 0.599323226440542
Glb1l ENSMUSG00000026200 0.216214347033995 0.374861176998505 0.926550375688041 0.926550375688041 0.249907451332337 0.374861176998505
Pfkfb3 ENSMUSG00000026773 0.044737329683373 0.134211989050119 0.852832278580641 0.852832278580641 0.300095920620218 0.450143880930327
St6galnac6 ENSMUSG00000026811 0.300095920620218 0.450143880930327 0.643853282854191 0.643853282854191 0.299349060054895 0.450143880930327
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Gnpda2 ENSMUSG00000029209 0.399548817627027 0.454942951775342 0.454942951775342 0.454942951775342 0.399548817627028 0.454942951775342
Phkg2 ENSMUSG00000030815 0.347639524025037 0.7733472349452 0.853801250889739 0.853801250889739 0.5155648232968 0.7733472349452
Gpc4 ENSMUSG00000031119 0.120850531362929 0.362551594088788 1 1 0.577259514257969 0.865889271386954
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
Pkm ENSMUSG00000032294 1 1 0.92589277149125 1 0.346527959006435 1
Cspg5 ENSMUSG00000032482 0.297848640636702 0.521459286037555 0.78148726569172 0.78148726569172 0.347639524025037 0.521459286037555
Chpf ENSMUSG00000032997 0.78148726569172 0.853694531487825 0.853694531487825 0.853694531487825 0.455625354715449 0.853694531487825
Chst2 ENSMUSG00000033350 0.5155648232968 0.926003599371282 0.926003599371282 0.926003599371282 0.781170242226513 0.926003599371282
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
G6pc3 ENSMUSG00000034793 0.779888212132595 0.779888212132595 0.636229315311352 0.779888212132595 0.0763619660358786 0.229085898107636
Chst12 ENSMUSG00000036599 0.643853282854191 0.965779924281287 1 1 0.514934023620345 0.965779924281287
Aaas ENSMUSG00000036678 0.384672302267076 0.834114530696274 0.556076353797516 0.834114530696274 0.848399006995053 0.848399006995053
Hgsnat ENSMUSG00000037260 0.0766111619812295 0.229833485943689 0.450794830295118 0.450794830295118 0.333146020247509 0.450794830295118
Chst7 ENSMUSG00000037347 0.254414773803597 0.381622160705395 0.395928178642446 0.395928178642446 0.120545895661628 0.361637686984883
Hs3st6 ENSMUSG00000039628 0.78132892626786 0.78132892626786 0.296717426617605 0.78132892626786 0.780692109850228 0.78132892626786
Hs2st1 ENSMUSG00000040151 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155 0.180293335960318 0.540880007880955
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
Hs3st2 ENSMUSG00000046321 0.853801250889739 0.853801250889739 0.454600801949285 0.853801250889739 0.782117202022501 0.853801250889739
B3gnt1 ENSMUSG00000047379 0.7802108304765 0.7802108304765 0.707899741868332 0.7802108304765 0.299349060054895 0.7802108304765
Gnpda1 ENSMUSG00000052102 0.853801250889739 0.853801250889739 0.853372965654504 0.853801250889739 0.21549027811633 0.64647083434899
Aldh1a1 ENSMUSG00000053279 0.140165358447409 0.307762054892242 0.205174703261494 0.307762054892242 0.451840588205062 0.451840588205062
Ndst1 ENSMUSG00000054008 0.709375484777034 0.853049270252403 0.853049270252403 0.853049270252403 0.454600801949285 0.853049270252403
B4galt6 ENSMUSG00000056124 0.058823267388015 0.176469802164045 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993
Gpc6 ENSMUSG00000058571 1 1 0.119936171404379 0.359808514213138 0.643853282854191 0.965779924281287
Ext1 ENSMUSG00000061731 0.347639524025037 0.521459286037555 0.148115998140416 0.444347994421247 0.926658283600152 0.926658283600152
Ppp1r3c ENSMUSG00000067279 0.642366752097095 0.852065168704833 0.852065168704833 0.852065168704833 0.392243127063687 0.852065168704833
B3gat3 ENSMUSG00000071649 0.255901190956604 0.383851786434906 0.575536202757516 0.575536202757516 0.252920381501206 0.383851786434906
B3gnt7 ENSMUSG00000079445 0.398108175780842 0.963550128145642 1 1 0.642366752097095 0.963550128145642

Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Activation of G protein gated Potassium channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabbr1 ENSMUSG00000024462 1 1 0.711034989117171 1 0.853694531487825 1
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Kcnj9 ENSMUSG00000038026 1 1 0.926658283600152 1 0.5155648232968 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Kcnj16 ENSMUSG00000051497 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.578396848531894 0.926550375688041
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Clathrin-mediated endocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Epn2 ENSMUSG00000001036 0.454600801949285 0.853694531487825 0.853694531487825 0.853694531487825 0.643359829732651 0.853694531487825
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Ap2a2 ENSMUSG00000002957 0.711034989117171 0.852065168704833 0.852065168704833 0.852065168704833 0.454942951775341 0.852065168704833
Sh3gl1 ENSMUSG00000003200 0.926003599371282 0.926003599371282 0.643853282854191 0.926003599371282 0.345410946355104 0.926003599371282
D130043K22Rik ENSMUSG00000006711 0.578396848531894 0.867595272797842 0.179249687218049 0.537749061654148 1 1
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Cops3 ENSMUSG00000019373 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Amph ENSMUSG00000021314 0.853694531487825 0.853694531487825 0.779238691542963 0.853694531487825 0.575536202757516 0.853694531487825
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Sh3gl2 ENSMUSG00000028488 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.5155648232968 0.853372965654504
Dnajc6 ENSMUSG00000028528 0.577829325134931 0.866743987702397 1 1 0.299349060054895 0.866743987702397
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Epgn ENSMUSG00000035020 0.778088064569037 0.778088064569037 0.337049057953584 0.666591427564543 0.444394285043028 0.666591427564543
Ap2b1 ENSMUSG00000035152 0.852175490580835 0.852175490580835 0.291756209988535 0.437634314982802 0.216214347033995 0.437634314982802
Epn1 ENSMUSG00000035203 0.578113371816017 0.926441990075769 0.926441990075769 0.926441990075769 0.78148726569172 0.926441990075769
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Ap2a1 ENSMUSG00000060279 0.926550375688041 0.926550375688041 0.853372965654504 0.926550375688041 0.711240436189781 0.926550375688041
Syt11 ENSMUSG00000068923 0.706831781264721 0.706831781264721 0.567818482366294 0.706831781264721 0.346899083932133 0.706831781264721
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517
Btc ENSMUSG00000082361 0.0964252305385472 0.144637845807821 0.21549027811633 0.21549027811633 0.00731348855817121 0.0219404656745136

Activation of Ca-permeable Kainate Receptor

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642

Ionotropic activity of kainate receptors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlg3 ENSMUSG00000000881 0.711240436189781 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grik5 ENSMUSG00000003378 0.146141353215796 0.438424059647387 0.343537039781257 0.515305559671886 0.711854160331342 0.711854160331342
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Grik4 ENSMUSG00000032017 0.782117202022501 0.782117202022501 0.514934023620344 0.7733472349452 0.5155648232968 0.7733472349452
Grik2 ENSMUSG00000056073 0.642366752097095 0.963550128145642 1 1 0.400265374208516 0.963550128145642

Serotonin Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041

Heparan sulfate/heparin (HS-GAG) metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
B4galt7 ENSMUSG00000021504 0.455625354715448 0.455625354715448 0.146800541856249 0.323235417174495 0.21549027811633 0.323235417174495
Glb1l ENSMUSG00000026200 0.216214347033995 0.374861176998505 0.926550375688041 0.926550375688041 0.249907451332337 0.374861176998505
Gpc4 ENSMUSG00000031119 0.120850531362929 0.362551594088788 1 1 0.577259514257969 0.865889271386954
Cspg5 ENSMUSG00000032482 0.297848640636702 0.521459286037555 0.78148726569172 0.78148726569172 0.347639524025037 0.521459286037555
Gpc1 ENSMUSG00000034220 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.297848640636702 0.853372965654504
Hgsnat ENSMUSG00000037260 0.0766111619812295 0.229833485943689 0.450794830295118 0.450794830295118 0.333146020247509 0.450794830295118
Hs3st6 ENSMUSG00000039628 0.78132892626786 0.78132892626786 0.296717426617605 0.78132892626786 0.780692109850228 0.78132892626786
Hs2st1 ENSMUSG00000040151 0.45596561163947 0.683948417459205 0.78180291566155 0.78180291566155 0.180293335960318 0.540880007880955
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
Hs3st2 ENSMUSG00000046321 0.853801250889739 0.853801250889739 0.454600801949285 0.853801250889739 0.782117202022501 0.853801250889739
Ndst1 ENSMUSG00000054008 0.709375484777034 0.853049270252403 0.853049270252403 0.853049270252403 0.454600801949285 0.853049270252403
Gpc6 ENSMUSG00000058571 1 1 0.119936171404379 0.359808514213138 0.643853282854191 0.965779924281287
Ext1 ENSMUSG00000061731 0.347639524025037 0.521459286037555 0.148115998140416 0.444347994421247 0.926658283600152 0.926658283600152
B3gat3 ENSMUSG00000071649 0.255901190956604 0.383851786434906 0.575536202757516 0.575536202757516 0.252920381501206 0.383851786434906

DAG and IP3 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Adcy9 ENSMUSG00000005580 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739 0.711854160331342 0.853801250889739
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Adcy1 ENSMUSG00000020431 1 1 0.641867098978198 0.962800648467296 0.45596561163947 0.962800648467296
Adcy3 ENSMUSG00000020654 0.850948190971883 0.850948190971883 0.0564200190955604 0.169260057286681 0.574375606171923 0.850948190971883
Camkk1 ENSMUSG00000020785 0.576973746230334 0.710416009055326 0.710416009055326 0.710416009055326 0.513026869856283 0.710416009055326
Adrbk1 ENSMUSG00000024858 0.400265374208515 0.600398061312773 0.926550375688041 0.926550375688041 0.299349060054895 0.600398061312773
Camkk2 ENSMUSG00000029471 0.397384062266614 0.926333123228344 0.926333123228344 0.926333123228344 0.853480389728993 0.926333123228344
Prkce ENSMUSG00000045038 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.7802108304765 0.78148726569172

TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor 2 (TLR2) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor 5 (TLR5) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

PI Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Pip4k2b ENSMUSG00000018547 0.926441990075769 1 1 1 0.45596561163947 1
Pip4k2c ENSMUSG00000025417 0.5155648232968 0.642366752097095 0.642366752097095 0.642366752097095 0.577829325134931 0.642366752097095
Pi4k2b ENSMUSG00000029186 0.120545895661627 0.270440003940477 0.180293335960318 0.270440003940477 0.853907737111068 0.853907737111068
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Gde1 ENSMUSG00000033917 0.853801250889739 1 0.926550375688041 1 1 1
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Mtmr9 ENSMUSG00000035078 0.454942951775342 0.682414427663012 0.711034989117171 0.711034989117171 0.148772260628989 0.446316781886967
Pi4kb ENSMUSG00000038861 0.575536202757516 0.863304304136274 1 1 0.291756209988535 0.863304304136274
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739
Pitpnb ENSMUSG00000050017 0.853372965654504 0.853801250889739 0.853801250889739 0.853801250889739 0.514934023620345 0.853801250889739
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205

Toll Like Receptor 9 (TLR9) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor TLR1:TLR2 Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

MyD88 cascade initiated on plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor TLR6:TLR2 Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor 10 (TLR10) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Asparagine N-linked glycosylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Neu1 ENSMUSG00000007038 0.514934023620344 0.711240436189781 0.711240436189781 0.711240436189781 0.453570536021945 0.711240436189781
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Dhdds ENSMUSG00000012117 0.572616808177226 0.778253541606068 0.778253541606068 0.778253541606068 0.255530331334266 0.766590994002797
Ankrd28 ENSMUSG00000014496 0.781645261743309 0.781645261743309 0.297472133192261 0.76322556548407 0.508817043656047 0.76322556548407
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Pmm2 ENSMUSG00000022711 0.781170242226513 0.926003599371281 0.926003599371281 0.926003599371281 0.0964252305385472 0.289275691615642
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Cnih2 ENSMUSG00000024873 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739 0.643359829732651 0.853801250889739
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
St8sia5 ENSMUSG00000025425 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.711034989117171 0.78148726569172
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cnih3 ENSMUSG00000026514 0.643359829732651 0.711854160331342 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342
St6galnac6 ENSMUSG00000026811 0.300095920620218 0.450143880930327 0.643853282854191 0.643853282854191 0.299349060054895 0.450143880930327
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Alg8 ENSMUSG00000035704 1 1 0.92616891281798 1 0.39335551479284 1
Mgat4b ENSMUSG00000036620 0.398108175780842 0.778911768167544 0.708534948098331 0.778911768167544 0.778911768167544 0.778911768167544
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Alg2 ENSMUSG00000039740 0.214037080764326 0.300095920620218 0.236337185850513 0.300095920620218 0.300095920620218 0.300095920620218
Npl ENSMUSG00000042684 0.295201212209107 0.442801818313661 0.576687400573867 0.576687400573867 0.146471068967595 0.439413206902786
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
Trappc9 ENSMUSG00000047921 0.514300775319626 0.771451162979439 0.852940894477647 0.852940894477647 0.342405296020881 0.771451162979439
Slc17a5 ENSMUSG00000049624 0.294820734456232 0.884462203368697 0.782117202022501 0.926550375688041 0.926550375688041 0.926550375688041
Slc35c1 ENSMUSG00000049922 0.255901190956604 0.345410946355104 0.255530331334266 0.345410946355104 0.345410946355104 0.345410946355104
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Ppp6r1 ENSMUSG00000052296 0.254414773803597 0.682414427663012 1 1 0.454942951775341 0.682414427663012
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
B4galt6 ENSMUSG00000056124 0.058823267388015 0.176469802164045 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993
Chst8 ENSMUSG00000060402 0.853801250889739 0.853801250889739 0.514934023620345 0.772401035430517 0.454942951775341 0.772401035430517
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595

Dopamine Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Apba1 ENSMUSG00000024897 0.514934023620345 0.514934023620345 0.397384062266614 0.514934023620345 0.297848640636702 0.514934023620345
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041

Intra-Golgi and retrograde Golgi-to-ER traffic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyth2 ENSMUSG00000003269 0.853801250889739 1 0.45596561163947 1 1 1
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Vps53 ENSMUSG00000017288 0.640355507848752 0.85117361048289 0.85117361048289 0.85117361048289 0.346527959006435 0.85117361048289
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Vps54 ENSMUSG00000020128 0.120850531362929 0.29252580908486 0.29252580908486 0.29252580908486 0.255530331334266 0.29252580908486
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Kif3c ENSMUSG00000020668 0.781170242226513 0.781170242226513 0.708534948098331 0.781170242226513 0.345410946355104 0.781170242226513
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Racgap1 ENSMUSG00000023015 0.853801250889739 0.853801250889739 0.344663224299303 0.7733472349452 0.5155648232968 0.7733472349452
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Vti1a ENSMUSG00000024983 0.926003599371282 0.926003599371282 0.576112968612194 0.864169452918291 0.300095920620218 0.864169452918291
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Stx6 ENSMUSG00000026470 0.0969812105731563 0.290943631719469 0.852065168704833 0.852065168704833 0.216214347033995 0.324321520550992
Golga1 ENSMUSG00000026754 0.514934023620345 0.772401035430517 0.926658283600152 0.926658283600152 0.45596561163947 0.772401035430517
Kif3b ENSMUSG00000027475 0.400265374208515 0.853694531487825 0.853694531487825 0.853694531487825 0.578113371816017 0.853694531487825
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Gcc1 ENSMUSG00000029708 0.642366752097095 1 1 1 0.853801250889739 1
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Rab6b ENSMUSG00000032549 0.853694531487825 1 1 1 0.5155648232968 1
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Bicd2 ENSMUSG00000037933 0.283930443883615 0.851791331650844 0.926333123228344 0.926333123228344 0.926333123228344 0.926333123228344
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Kif1b ENSMUSG00000063077 0.514934023620345 0.7733472349452 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Rab18 ENSMUSG00000073639 0.115037265385284 0.345111796155853 0.45596561163947 0.45596561163947 0.451840588205062 0.45596561163947

Golgi-to-ER retrograde transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Kif3c ENSMUSG00000020668 0.781170242226513 0.781170242226513 0.708534948098331 0.781170242226513 0.345410946355104 0.781170242226513
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Racgap1 ENSMUSG00000023015 0.853801250889739 0.853801250889739 0.344663224299303 0.7733472349452 0.5155648232968 0.7733472349452
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Kif3b ENSMUSG00000027475 0.400265374208515 0.853694531487825 0.853694531487825 0.853694531487825 0.578113371816017 0.853694531487825
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Rab6b ENSMUSG00000032549 0.853694531487825 1 1 1 0.5155648232968 1
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Bicd2 ENSMUSG00000037933 0.283930443883615 0.851791331650844 0.926333123228344 0.926333123228344 0.926333123228344 0.926333123228344
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Kif1b ENSMUSG00000063077 0.514934023620345 0.7733472349452 0.926658283600152 0.926658283600152 0.5155648232968 0.7733472349452
Rab18 ENSMUSG00000073639 0.115037265385284 0.345111796155853 0.45596561163947 0.45596561163947 0.451840588205062 0.45596561163947

Extra-nuclear estrogen signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Uhmk1 ENSMUSG00000026667 0.147458757705094 0.221188136557642 0.00283103937188884 0.00849311811566652 0.450444934184774 0.450444934184774
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Epgn ENSMUSG00000035020 0.778088064569037 0.778088064569037 0.337049057953584 0.666591427564543 0.444394285043028 0.666591427564543
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
S1pr3 ENSMUSG00000067586 0.297095062262362 0.445642593393544 0.573498913947369 0.573498913947369 0.119631084167592 0.358893252502775
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606
Btc ENSMUSG00000082361 0.0964252305385472 0.144637845807821 0.21549027811633 0.21549027811633 0.00731348855817121 0.0219404656745136

MyD88 dependent cascade initiated on endosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Classical Kir channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Kcnj2 ENSMUSG00000041695 0.177153312234059 0.515305559671886 0.781170242226513 0.781170242226513 0.343537039781257 0.515305559671886
Kcnj12 ENSMUSG00000042529 0.853801250889739 0.853801250889739 0.45596561163947 0.683948417459205 0.180293335960318 0.540880007880955
Kcnj14 ENSMUSG00000058743 0.400265374208515 0.400265374208515 0.0964252305385472 0.269918683616058 0.179945789077372 0.269918683616058

FOXO-mediated transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt2 ENSMUSG00000004056 0.179945789077372 0.539837367232115 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Akt3 ENSMUSG00000019699 0.348008842235184 0.926658283600152 0.853801250889739 0.926658283600152 0.926658283600152 0.926658283600152
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Foxo3 ENSMUSG00000048756 0.851732715229127 0.851732715229127 0.779888212132595 0.851732715229127 0.399548817627028 0.851732715229127
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Foxo6 ENSMUSG00000052135 0.246861959455465 0.740585878366394 0.514934023620345 0.772401035430517 1 1

Glutamate Neurotransmitter Release Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ppfia3 ENSMUSG00000003863 0.398108175780842 0.576973746230334 0.576973746230334 0.576973746230334 0.514934023620344 0.576973746230334
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Stxbp1 ENSMUSG00000026797 0.711650020253571 0.852504981253341 0.852504981253341 0.852504981253341 0.514934023620345 0.852504981253341
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Bzrap1 ENSMUSG00000034156 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.213307944885796 0.319961917328694
Syt1 ENSMUSG00000035864 0.120545895661627 0.361637686984882 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Slc17a7 ENSMUSG00000070570 0.514934023620345 1 0.712057867818062 1 1 1

Post-translational protein modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rab5b ENSMUSG00000000711 0.347639524025037 0.521459286037555 1 1 0.300095920620218 0.521459286037555
Cfp ENSMUSG00000001128 0.452880492349546 0.642366752097095 0.397384062266614 0.642366752097095 0.642366752097095 0.642366752097095
Ddb2 ENSMUSG00000002109 0.853801250889739 0.926658283600152 0.254414773803597 0.763244321410792 0.926658283600152 0.926658283600152
Hltf ENSMUSG00000002428 0.575536202757516 1 1 1 0.853372965654504 1
Keap1 ENSMUSG00000003308 0.342405296020881 0.600398061312773 0.642366752097095 0.642366752097095 0.400265374208515 0.600398061312773
Large ENSMUSG00000004383 0.5155648232968 0.711650020253571 0.711650020253571 0.711650020253571 0.643853282854191 0.711650020253571
Tpr ENSMUSG00000006005 0.572911448356892 0.78132892626786 0.78132892626786 0.78132892626786 0.710208797518812 0.78132892626786
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Stambp ENSMUSG00000006906 0.0566379395854604 0.119631084167592 0.119631084167592 0.119631084167592 0.0969812105731562 0.119631084167592
Neu1 ENSMUSG00000007038 0.514934023620344 0.711240436189781 0.711240436189781 0.711240436189781 0.453570536021945 0.711240436189781
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Dhdds ENSMUSG00000012117 0.572616808177226 0.778253541606068 0.778253541606068 0.778253541606068 0.255530331334266 0.766590994002797
Ttll5 ENSMUSG00000012609 0.17750354896016 0.26625532344024 0.343537039781257 0.343537039781257 0.17433930265919 0.26625532344024
Klhl3 ENSMUSG00000014164 0.78180291566155 0.78180291566155 0.643359829732651 0.78180291566155 0.399548817627028 0.78180291566155
Ube2z ENSMUSG00000014349 0.573205482926791 0.706831781264721 0.706831781264721 0.706831781264721 0.456305241393103 0.706831781264721
Ankrd28 ENSMUSG00000014496 0.781645261743309 0.781645261743309 0.297472133192261 0.76322556548407 0.508817043656047 0.76322556548407
Hspa8 ENSMUSG00000015656 0.0241933715424142 0.0725801146272427 0.399548817627028 0.599323226440542 1 1
Rxra ENSMUSG00000015846 0.853801250889739 0.853801250889739 0.345037391052887 0.51755608657933 0.179945789077372 0.51755608657933
Igfbp4 ENSMUSG00000017493 0.853694531487825 0.926550375688041 0.926550375688041 0.926550375688041 0.45596561163947 0.926550375688041
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab3d ENSMUSG00000019066 0.853372965654504 0.853372965654504 0.853049270252403 0.853372965654504 0.781170242226513 0.853372965654504
Rab5c ENSMUSG00000019173 0.853372965654504 0.853372965654504 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Cops3 ENSMUSG00000019373 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155
Tnfaip3 ENSMUSG00000019850 0.78180291566155 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Cdc34 ENSMUSG00000020307 0.254414773803596 0.348008842235184 0.348008842235184 0.348008842235184 0.255901190956604 0.348008842235184
Fstl3 ENSMUSG00000020325 0.576973746230334 0.711650020253571 0.345410946355104 0.711650020253571 0.711650020253571 0.711650020253571
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Fam20a ENSMUSG00000020614 0.0331400397096515 0.0994201191289545 0.300095920620218 0.300095920620218 0.146141353215796 0.219212029823694
Rnf144a ENSMUSG00000020642 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342 0.450094379653806 0.711854160331342
Aurkb ENSMUSG00000020897 0.92380865295296 0.92380865295296 0.00477055016690543 0.0143116505007163 0.255530331334266 0.383295497001398
Galnt16 ENSMUSG00000021130 0.213307944885796 0.319961917328694 0.711650020253571 0.711650020253571 0.148772260628989 0.319961917328694
Otub2 ENSMUSG00000021203 1 1 0.577829325134931 1 0.712057867818062 1
Traf3 ENSMUSG00000021277 0.643853282854191 0.643853282854191 0.454942951775341 0.643853282854191 0.0953125666339397 0.285937699901819
Arsk ENSMUSG00000021592 0.642864324224729 1 1 1 0.853480389728993 1
Kctd6 ENSMUSG00000021752 0.347639524025037 0.521459286037555 0.0761127945805735 0.228338383741721 0.926441990075769 0.926441990075769
Bap1 ENSMUSG00000021901 0.395196379647461 0.592794569471191 0.781170242226513 0.781170242226513 0.348008842235184 0.592794569471191
Fbxl3 ENSMUSG00000022124 0.711034989117171 0.711034989117171 0.180293335960318 0.522013263352777 0.348008842235184 0.522013263352777
Dcaf13 ENSMUSG00000022300 0.852940894477647 0.926550375688041 0.926550375688041 0.926550375688041 0.643853282854191 0.926550375688041
Rangap1 ENSMUSG00000022391 0.642366752097095 0.642366752097095 0.29252580908486 0.43878871362729 0.254414773803597 0.43878871362729
L3mbtl2 ENSMUSG00000022394 0.774176834800231 0.774176834800231 0.508488713161374 0.762733069742061 0.0930846407079412 0.279253922123824
Pmm2 ENSMUSG00000022711 0.781170242226513 0.926003599371281 0.926003599371281 0.926003599371281 0.0964252305385472 0.289275691615642
Klhl22 ENSMUSG00000022750 0.255530331334266 0.255530331334266 0.179249687218049 0.255530331334266 0.213307944885796 0.255530331334266
Tomm70a ENSMUSG00000022752 0.5155648232968 0.5155648232968 0.398108175780842 0.5155648232968 0.254787123615605 0.5155648232968
Mfi2 ENSMUSG00000022780 0.0964252305385472 0.289275691615642 0.295581119060361 0.443371678590541 0.711650020253571 0.711650020253571
Muc13 ENSMUSG00000022824 0.926604389137101 0.926604389137101 0.0209878658739169 0.0629635976217507 0.781960228679124 0.926604389137101
Ahsg ENSMUSG00000022868 0.397384062266614 0.397384062266614 0.347639524025037 0.397384062266614 0.299349060054895 0.397384062266614
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Pros1 ENSMUSG00000022912 0.926441990075769 0.926441990075769 0.45596561163947 0.683948417459205 0.0969812105731561 0.290943631719468
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Satb1 ENSMUSG00000023927 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.578113371816017 0.926550375688041
Galnt14 ENSMUSG00000024064 0.514300775319626 0.771451162979439 0.216214347033995 0.648643041101984 0.92622377157404 0.92622377157404
Prss41 ENSMUSG00000024114 0.147787500009832 0.443362500029497 0.450444934184774 0.675667401277161 0.925948247631505 0.925948247631505
Tmem132a ENSMUSG00000024736 0.400265374208515 0.600398061312773 0.252920381501207 0.600398061312773 0.782117202022501 0.782117202022501
Otub1 ENSMUSG00000024767 0.245326864841171 0.245326864841171 0.149930038858385 0.245326864841171 0.208897379073412 0.245326864841171
Stambpl1 ENSMUSG00000024776 0.010906560635693 0.0327196819070789 0.213307944885796 0.297848640636703 0.297848640636703 0.297848640636703
Il33 ENSMUSG00000024810 0.346899083932133 1 1 1 0.853801250889739 1
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Cnih2 ENSMUSG00000024873 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739 0.643359829732651 0.853801250889739
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
St8sia5 ENSMUSG00000025425 0.78148726569172 0.78148726569172 0.711034989117171 0.78148726569172 0.711034989117171 0.78148726569172
Usp16 ENSMUSG00000025616 0.78180291566155 0.926658283600152 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152
Pigq ENSMUSG00000025728 0.926550375688041 0.926550375688041 0.78180291566155 0.926550375688041 0.0583853430099098 0.175156029029729
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Lypd1 ENSMUSG00000026344 0.853372965654504 0.853372965654504 0.0434194723707708 0.130258417112312 0.578113371816017 0.853372965654504
Cnih3 ENSMUSG00000026514 0.643359829732651 0.711854160331342 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342
Dcaf8 ENSMUSG00000026554 1 1 0.453570536021945 0.680355804032917 0.298599969973533 0.680355804032917
Lypd6b ENSMUSG00000026765 0.642864324224729 0.642864324224729 0.120545895661628 0.361637686984883 0.346899083932133 0.520348625898199
St6galnac6 ENSMUSG00000026811 0.300095920620218 0.450143880930327 0.643853282854191 0.643853282854191 0.299349060054895 0.450143880930327
Rtf1 ENSMUSG00000027304 0.514934023620345 0.772401035430517 0.926333123228344 0.926333123228344 0.514934023620345 0.772401035430517
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Ccna2 ENSMUSG00000027715 0.853372965654504 0.853372965654504 0.0230207752632623 0.0690623257897868 0.178901132102685 0.268351698154027
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
St3gal3 ENSMUSG00000028538 0.342026805366747 0.683438032073173 0.708534948098331 0.708534948098331 0.455625354715449 0.683438032073173
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Pex14 ENSMUSG00000028975 0.451840588205062 0.677760882307593 0.709375484777034 0.709375484777034 0.347639524025037 0.677760882307593
Uchl1 ENSMUSG00000029223 0.643853282854191 0.643853282854191 0.0443599545252853 0.133079863575856 0.5155648232968 0.643853282854191
Wsb2 ENSMUSG00000029364 0.578396848531894 0.853049270252403 0.853049270252403 0.853049270252403 0.5155648232968 0.853049270252403
Kbtbd8 ENSMUSG00000030031 0.345037391052887 0.44690942336404 0.44690942336404 0.44690942336404 0.252545530864481 0.44690942336404
Ruvbl1 ENSMUSG00000030079 0.509144723230069 0.509144723230069 0.205174703261494 0.307762054892242 0.144157978128026 0.307762054892242
Fbxl19 ENSMUSG00000030811 0.78180291566155 0.78180291566155 0.400265374208515 0.683948417459205 0.45596561163947 0.683948417459205
Mettl10 ENSMUSG00000030960 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.639337105615665 0.926550375688041
F9 ENSMUSG00000031138 0.252545530864481 0.378818296296722 0.84816072370727 0.84816072370727 0.223767744186665 0.378818296296722
Gas6 ENSMUSG00000031451 0.7802108304765 1 1 1 0.214037080764326 0.642111242292977
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
St3gal2 ENSMUSG00000031749 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.399548817627028 0.926550375688041
Rab3a ENSMUSG00000031840 1 1 1 1 0.5155648232968 1
Pgr ENSMUSG00000031870 0.454600801949285 0.454600801949285 0.295581119060361 0.447899954960299 0.298599969973533 0.447899954960299
Aplp2 ENSMUSG00000031996 0.851061028660105 0.851061028660105 0.707899741868332 0.851061028660105 0.293293089483362 0.851061028660105
Usp28 ENSMUSG00000032267 0.851954599472143 1 1 1 0.1168786685029 0.350636005508699
Usp3 ENSMUSG00000032376 0.711034989117171 0.711034989117171 0.21549027811633 0.323235417174495 0.0761127945805735 0.228338383741721
Smad3 ENSMUSG00000032402 1 1 0.77858338846904 1 0.514934023620345 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Rab6b ENSMUSG00000032549 0.853694531487825 1 1 1 0.5155648232968 1
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Psmf1 ENSMUSG00000032869 0.505838378028518 0.758757567042777 1 1 0.295581119060361 0.758757567042777
Galnt9 ENSMUSG00000033316 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.578113371816017 0.78180291566155
Otud7a ENSMUSG00000033510 0.454600801949285 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Asb13 ENSMUSG00000033781 0.643359829732651 0.853694531487825 0.5155648232968 0.853694531487825 0.853694531487825 0.853694531487825
Wbscr17 ENSMUSG00000034040 0.643359829732651 0.643359829732651 0.576973746230334 0.643359829732651 0.45596561163947 0.643359829732651
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Alg8 ENSMUSG00000035704 1 1 0.92616891281798 1 0.39335551479284 1
Siah2 ENSMUSG00000036432 0.926003599371281 1 0.77858338846904 1 1 1
Adamts2 ENSMUSG00000036545 0.295581119060361 0.399548817627028 0.255901190956604 0.399548817627028 0.399548817627028 0.399548817627028
Mgat4b ENSMUSG00000036620 0.398108175780842 0.778911768167544 0.708534948098331 0.778911768167544 0.778911768167544 0.778911768167544
Aaas ENSMUSG00000036678 0.384672302267076 0.834114530696274 0.556076353797516 0.834114530696274 0.848399006995053 0.848399006995053
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Mbd5 ENSMUSG00000036792 0.393724994268831 0.643359829732651 0.643359829732651 0.643359829732651 0.575536202757516 0.643359829732651
Stag1 ENSMUSG00000037286 0.346899083932133 0.520348625898199 0.180293335960318 0.520348625898199 0.643853282854191 0.643853282854191
Vgf ENSMUSG00000037428 0.399548817627028 0.710001140920767 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Wdtc1 ENSMUSG00000037622 0.781170242226513 1 1 1 0.255901190956604 0.767703572869812
Rara ENSMUSG00000037992 0.297848640636702 0.576973746230334 0.399548817627028 0.576973746230334 0.576973746230334 0.576973746230334
Hrc ENSMUSG00000038239 0.84934104438081 0.84934104438081 0.454258017332816 0.681387025999225 0.344663224299303 0.681387025999225
Cntn5 ENSMUSG00000039488 0.180293335960318 0.270440003940477 0.5155648232968 0.5155648232968 0.118714930081337 0.270440003940477
Alg2 ENSMUSG00000039740 0.214037080764326 0.300095920620218 0.236337185850513 0.300095920620218 0.300095920620218 0.300095920620218
Spsb1 ENSMUSG00000039911 0.454600801949285 0.454600801949285 0.288654423610209 0.450143880930327 0.300095920620218 0.450143880930327
Fbxl4 ENSMUSG00000040410 0.7802108304765 0.7802108304765 0.334715083204387 0.7802108304765 0.643359829732651 0.7802108304765
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Pigs ENSMUSG00000041958 0.642366752097095 0.92622377157404 0.92622377157404 0.92622377157404 0.255530331334266 0.766590994002797
Dcaf17 ENSMUSG00000041966 0.78180291566155 0.78180291566155 0.144820068500793 0.21723010275119 0.0936419271039909 0.21723010275119
Npl ENSMUSG00000042684 0.295201212209107 0.442801818313661 0.576687400573867 0.576687400573867 0.146471068967595 0.439413206902786
Usp48 ENSMUSG00000043411 0.711854160331342 0.711854160331342 0.643359829732651 0.711854160331342 0.298599969973533 0.711854160331342
Fem1a ENSMUSG00000043683 0.642864324224729 0.926550375688041 0.578113371816017 0.926550375688041 0.926550375688041 0.926550375688041
Glb1 ENSMUSG00000045594 0.642864324224729 0.642864324224729 0.171859370212435 0.374861176998506 0.249907451332337 0.374861176998506
Pigz ENSMUSG00000045625 0.642366752097095 0.642366752097095 0.511742979522636 0.642366752097095 0.118409250205154 0.355227750615461
Sprn ENSMUSG00000045733 0.711034989117171 0.711034989117171 0.578113371816017 0.711034989117171 0.577829325134931 0.711034989117171
B3gnt1 ENSMUSG00000047379 0.7802108304765 0.7802108304765 0.707899741868332 0.7802108304765 0.299349060054895 0.7802108304765
Rnf152 ENSMUSG00000047496 0.398108175780842 0.597162263671263 0.0334587898203823 0.100376369461147 0.9255572759333 0.9255572759333
Trappc9 ENSMUSG00000047921 0.514300775319626 0.771451162979439 0.852940894477647 0.852940894477647 0.342405296020881 0.771451162979439
C1galt1c1 ENSMUSG00000048970 0.180293335960318 0.540880007880955 0.711854160331342 0.711854160331342 0.711650020253571 0.711854160331342
Dcaf5 ENSMUSG00000049106 0.78148726569172 0.78148726569172 0.642864324224729 0.78148726569172 0.297848640636702 0.78148726569172
Slc17a5 ENSMUSG00000049624 0.294820734456232 0.884462203368697 0.782117202022501 0.926550375688041 0.926550375688041 0.926550375688041
Slc35c1 ENSMUSG00000049922 0.255901190956604 0.345410946355104 0.255530331334266 0.345410946355104 0.345410946355104 0.345410946355104
Rtn4rl2 ENSMUSG00000050896 0.779238691542963 0.853694531487825 0.711650020253571 0.853694531487825 0.853694531487825 0.853694531487825
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Sema5b ENSMUSG00000052133 0.395196379647461 0.592794569471191 0.706831781264721 0.706831781264721 0.348008842235184 0.592794569471191
Bre ENSMUSG00000052139 0.392243127063687 0.766645874397711 0.776919261684345 0.776919261684345 0.511097249598474 0.766645874397711
Ppp6r1 ENSMUSG00000052296 0.254414773803597 0.682414427663012 1 1 0.454942951775341 0.682414427663012
Fbxo31 ENSMUSG00000052934 0.255901190956604 0.684457862089655 0.926003599371282 0.926003599371282 0.456305241393103 0.684457862089655
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
B4galt6 ENSMUSG00000056124 0.058823267388015 0.176469802164045 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993
Apol8 ENSMUSG00000056656 0.78180291566155 0.78180291566155 0.399548817627028 0.599323226440542 0.144820068500793 0.43446020550238
Thra ENSMUSG00000058756 0.514934023620344 0.772401035430517 0.926333123228344 0.926333123228344 0.300095920620218 0.772401035430517
B3gnt8 ENSMUSG00000059479 0.255530331334266 0.383295497001398 0.397746436553874 0.397746436553874 0.120545895661628 0.361637686984883
Ntm ENSMUSG00000059974 0.782117202022501 0.782117202022501 0.343537039781257 0.782117202022501 0.576973746230334 0.782117202022501
Chst8 ENSMUSG00000060402 0.853801250889739 0.853801250889739 0.514934023620345 0.772401035430517 0.454942951775341 0.772401035430517
Hist1h4c ENSMUSG00000060678 0.0165780605008444 0.0497341815025332 0.71082910328023 0.853801250889739 0.853801250889739 0.853801250889739
Lsamp ENSMUSG00000061080 0.300095920620218 0.300095920620218 0.253294730253594 0.300095920620218 0.0958690133561599 0.28760704006848
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Opcml ENSMUSG00000062257 0.120850531362929 0.362551594088788 0.711854160331342 0.782117202022501 0.782117202022501 0.782117202022501
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Msln ENSMUSG00000063011 0.5155648232968 1 0.711240436189781 1 1 1
Pomgnt2 ENSMUSG00000066235 0.642117186565222 0.642117186565222 0.120545895661627 0.361637686984882 0.254041925545275 0.381062888317912
Fbxl18 ENSMUSG00000066640 0.452880492349546 0.926003599371282 0.926003599371282 0.926003599371282 0.643359829732651 0.926003599371282
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595
Hist1h2bq ENSMUSG00000069307 0.775560609711725 0.778253541606068 0.338976281569376 0.778253541606068 0.778253541606068 0.778253541606068
Ndnl2 ENSMUSG00000070520 1 1 0.215127611919161 0.645382835757484 0.51398322803049 0.770974842045735
Rraga ENSMUSG00000070934 0.566593564630738 0.566593564630738 0.291756209988535 0.521459286037555 0.347639524025037 0.521459286037555
Apol7e ENSMUSG00000071716 0.505838378028518 0.505838378028518 0.44147815592779 0.505838378028518 0.495507824815002 0.505838378028518
Ccnf ENSMUSG00000072082 1 1 0.34837756124189 1 0.711854160331342 1
Rab18 ENSMUSG00000073639 0.115037265385284 0.345111796155853 0.45596561163947 0.45596561163947 0.451840588205062 0.45596561163947
Rab11b ENSMUSG00000077450 0.447265995733381 0.447265995733381 0.447265995733381 0.447265995733381 0.178901132102685 0.447265995733381
B3gnt7 ENSMUSG00000079445 0.398108175780842 0.963550128145642 1 1 0.642366752097095 0.963550128145642
Rab7 ENSMUSG00000079477 0.400265374208515 0.514934023620344 0.400265374208515 0.514934023620344 0.514934023620344 0.514934023620344

Toll Like Receptor 3 (TLR3) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Toll Like Receptor 7/8 (TLR7/8) Cascade

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Ly96 ENSMUSG00000025779 0.92622377157404 0.92622377157404 0.853801250889739 0.92622377157404 0.642366752097095 0.92622377157404
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

ER to Golgi Anterograde Transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Ankrd28 ENSMUSG00000014496 0.781645261743309 0.781645261743309 0.297472133192261 0.76322556548407 0.508817043656047 0.76322556548407
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Cnih2 ENSMUSG00000024873 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739 0.643359829732651 0.853801250889739
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cnih3 ENSMUSG00000026514 0.643359829732651 0.711854160331342 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Trappc9 ENSMUSG00000047921 0.514300775319626 0.771451162979439 0.852940894477647 0.852940894477647 0.342405296020881 0.771451162979439
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Ppp6r1 ENSMUSG00000052296 0.254414773803597 0.682414427663012 1 1 0.454942951775341 0.682414427663012
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595

RHO GTPase Effectors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Spc25 ENSMUSG00000005233 0.638051880670243 0.638051880670243 0.00555992428326542 0.0166797728497963 0.45149265530335 0.638051880670243
Kif5b ENSMUSG00000006740 0.39519637964746 0.59279456947119 0.252545530864481 0.59279456947119 0.643359829732651 0.643359829732651
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Cybb ENSMUSG00000015340 0.0969812105731564 0.145471815859735 0.926550375688041 0.926550375688041 0.024062085667391 0.072186257002173
Srf ENSMUSG00000015605 0.853372965654504 0.926003599371282 0.926003599371282 0.926003599371282 0.5155648232968 0.926003599371282
Ppp2r5c ENSMUSG00000017843 0.444394285043028 0.444394285043028 0.442211413534162 0.444394285043028 0.300095920620218 0.444394285043028
Ywhab ENSMUSG00000018326 0.400265374208515 0.578113371816017 0.0221230395928304 0.0663691187784912 0.578113371816017 0.578113371816017
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Ndel1 ENSMUSG00000018736 0.146800541856249 0.440401625568746 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Gopc ENSMUSG00000019861 0.398108175780842 0.600398061312773 0.400265374208515 0.600398061312773 0.926658283600152 0.926658283600152
Ska2 ENSMUSG00000020492 0.782117202022501 0.926441990075769 0.926441990075769 0.926441990075769 0.344663224299303 0.926441990075769
Dlg4 ENSMUSG00000020886 0.643359829732651 0.782117202022501 0.782117202022501 0.782117202022501 0.400265374208515 0.782117202022501
Dvl2 ENSMUSG00000020888 0.578396848531894 0.711240436189781 0.711240436189781 0.711240436189781 0.148772260628989 0.446316781886968
Aurkb ENSMUSG00000020897 0.92380865295296 0.92380865295296 0.00477055016690543 0.0143116505007163 0.255530331334266 0.383295497001398
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
Rangap1 ENSMUSG00000022391 0.642366752097095 0.642366752097095 0.29252580908486 0.43878871362729 0.254414773803597 0.43878871362729
Ptk2 ENSMUSG00000022607 0.514300775319626 0.865460619345501 0.926550375688041 0.926550375688041 0.576973746230334 0.865460619345501
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Cenpq ENSMUSG00000023919 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.398108175780842 0.926550375688041
Diap1 ENSMUSG00000024456 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155 0.179945789077372 0.324321520550992
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Actr3 ENSMUSG00000026341 0.146800541856249 0.378818296296722 0.252545530864481 0.378818296296722 0.643853282854191 0.643853282854191
Ahctf1 ENSMUSG00000026491 0.0936419271039906 0.140462890655986 0.708534948098331 0.708534948098331 0.0331400397096514 0.0994201191289543
Mapre1 ENSMUSG00000027479 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.643853282854191 0.853694531487825
Src ENSMUSG00000027646 0.709375484777034 0.926333123228344 0.926333123228344 0.926333123228344 0.300095920620218 0.900287761860654
Nudc ENSMUSG00000028851 0.343537039781257 0.442211413534162 0.442211413534162 0.442211413534162 0.299349060054895 0.442211413534162
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Cenpi ENSMUSG00000031262 0.853694531487825 0.853694531487825 0.0334587898203824 0.100376369461147 0.509144723230069 0.763717084845103
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Nckipsd ENSMUSG00000032598 0.513026869856283 0.513026869856283 0.205174703261494 0.513026869856283 0.453570536021945 0.513026869856283
Pik3c3 ENSMUSG00000033628 0.643853282854191 0.643853282854191 0.254414773803597 0.643853282854191 0.577829325134931 0.643853282854191
Myl12b ENSMUSG00000034868 0.643359829732651 0.643359829732651 0.255530331334266 0.447899954960299 0.298599969973533 0.447899954960299
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Rcc2 ENSMUSG00000040945 0.641867098978198 0.78148726569172 0.78148726569172 0.78148726569172 0.578113371816017 0.78148726569172
Cftr ENSMUSG00000041301 0.92616891281798 0.92616891281798 0.781960228679124 0.92616891281798 0.45149265530335 0.92616891281798
Cenph ENSMUSG00000045273 0.643359829732651 0.782117202022501 0.642366752097095 0.782117202022501 0.782117202022501 0.782117202022501
Ywhag ENSMUSG00000051391 1 1 0.711034989117171 1 0.347639524025037 1
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Arpc4 ENSMUSG00000079426 0.300095920620218 0.772401035430517 0.853372965654504 0.853372965654504 0.514934023620344 0.772401035430517

Semaphorin interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sema4d ENSMUSG00000021451 0.575536202757516 0.575536202757516 0.513665062682276 0.575536202757516 0.120545895661628 0.361637686984883
Gsk3b ENSMUSG00000022812 0.214037080764326 0.642111242292977 0.853801250889739 0.853801250889739 0.513665062682276 0.770497594023414
Hsp90ab1 ENSMUSG00000023944 0.852832278580641 0.92622377157404 0.92622377157404 0.92622377157404 0.455625354715449 0.92622377157404
Limk1 ENSMUSG00000029674 0.348008842235184 0.522013263352776 0.578113371816017 0.578113371816017 0.093084640707941 0.279253922123823
Plxna4 ENSMUSG00000029765 0.216214347033995 0.449023590082343 0.78180291566155 0.78180291566155 0.299349060054895 0.449023590082343
Plxna1 ENSMUSG00000030084 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.294820734456232 0.642864324224729
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Sema7a ENSMUSG00000038264 0.400265374208515 0.867170057724026 0.926441990075769 0.926441990075769 0.578113371816017 0.867170057724026
Arhgef11 ENSMUSG00000041977 0.455284468727762 0.455284468727762 0.399189600887034 0.455284468727762 0.298974794311434 0.455284468727762
Cdk5r1 ENSMUSG00000048895 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152 0.782117202022501 0.926658283600152
Rhob ENSMUSG00000054364 0.45596561163947 0.853372965654504 0.853372965654504 0.853372965654504 0.778911768167544 0.853372965654504
Rnd1 ENSMUSG00000054855 0.643853282854191 0.710208797518812 0.710208797518812 0.710208797518812 0.0964252305385472 0.289275691615642
Grlf1 ENSMUSG00000058230 0.300095920620218 0.450143880930327 1 1 0.254414773803597 0.450143880930327

Transport to the Golgi and subsequent modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Napa ENSMUSG00000006024 0.249528554620971 0.679838753181399 0.777922216623952 0.777922216623952 0.453225835454266 0.679838753181399
Stx5a ENSMUSG00000010110 0.853694531487825 0.853694531487825 0.295581119060361 0.599323226440542 0.399548817627028 0.599323226440542
Kdelr3 ENSMUSG00000010830 0.780851835278818 0.780851835278818 0.711854160331342 0.780851835278818 0.213307944885796 0.639923834657388
Ankrd28 ENSMUSG00000014496 0.781645261743309 0.781645261743309 0.297472133192261 0.76322556548407 0.508817043656047 0.76322556548407
Dync1h1 ENSMUSG00000018707 0.297848640636702 0.520348625898199 0.92622377157404 0.92622377157404 0.346899083932133 0.520348625898199
Rab1 ENSMUSG00000020149 0.514934023620345 0.772401035430517 0.0199974585097312 0.0599923755291937 0.925444427431699 0.925444427431699
Arf5 ENSMUSG00000020440 0.148772260628989 0.446316781886967 0.297848640636702 0.446772960955053 0.925444427431699 0.925444427431699
Tuba1b ENSMUSG00000023004 0.575824878403157 0.575824878403157 0.447621891168214 0.575824878403157 0.297095062262362 0.575824878403157
Rab1b ENSMUSG00000024870 1 1 0.711034989117171 1 0.254414773803597 0.763244321410791
Cnih2 ENSMUSG00000024873 0.853801250889739 0.853801250889739 0.782117202022501 0.853801250889739 0.643359829732651 0.853801250889739
Dctn2 ENSMUSG00000025410 0.345410946355104 0.597162263671263 1 1 0.398108175780842 0.597162263671263
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cnih3 ENSMUSG00000026514 0.643359829732651 0.711854160331342 0.578113371816017 0.711854160331342 0.711854160331342 0.711854160331342
Arfgap1 ENSMUSG00000027575 0.120850531362929 0.362551594088788 0.926003599371282 0.926003599371282 0.299349060054895 0.449023590082343
B4galt2 ENSMUSG00000028541 0.346899083932133 0.772401035430517 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517
Capzb ENSMUSG00000028745 0.640355507848752 0.851061028660105 0.851061028660105 0.851061028660105 0.255901190956604 0.767703572869812
Dctn6 ENSMUSG00000031516 0.643359829732651 0.965039744598977 0.298599969973533 0.895799909920599 1 1
Dync1li1 ENSMUSG00000032435 0.578113371816017 0.578113371816017 0.514934023620344 0.578113371816017 0.454600801949285 0.578113371816017
Bet1 ENSMUSG00000032757 0.853907737111068 0.853907737111068 0.643359829732651 0.853907737111068 0.45596561163947 0.853907737111068
Nsf ENSMUSG00000034187 0.926333123228344 0.926333123228344 0.575824878403157 0.863737317604735 0.453570536021945 0.863737317604735
Mgat4b ENSMUSG00000036620 0.398108175780842 0.778911768167544 0.708534948098331 0.778911768167544 0.778911768167544 0.778911768167544
Tubb4b ENSMUSG00000036752 0.640861491578951 0.640861491578951 0.446194239410717 0.640861491578951 0.297095062262362 0.640861491578951
Trappc9 ENSMUSG00000047921 0.514300775319626 0.771451162979439 0.852940894477647 0.852940894477647 0.342405296020881 0.771451162979439
Arf3 ENSMUSG00000051853 0.454942951775341 0.683948417459205 0.9255572759333 0.9255572759333 0.45596561163947 0.683948417459205
Ppp6r1 ENSMUSG00000052296 0.254414773803597 0.682414427663012 1 1 0.454942951775341 0.682414427663012
Arfgap3 ENSMUSG00000054277 0.338976281569376 0.338976281569376 0.299349060054895 0.338976281569376 0.0761127945805736 0.228338383741721
B4galt6 ENSMUSG00000056124 0.058823267388015 0.176469802164045 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993
Chst8 ENSMUSG00000060402 0.853801250889739 0.853801250889739 0.514934023620345 0.772401035430517 0.454942951775341 0.772401035430517
Stx17 ENSMUSG00000061455 0.398108175780842 0.398108175780842 0.395928178642446 0.398108175780842 0.253294730253594 0.398108175780842
Tubb4a ENSMUSG00000062591 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.514934023620345 0.852504981253341
Sptbn2 ENSMUSG00000067889 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.643853282854191 0.78180291566155
Cd59b ENSMUSG00000068686 0.577259514257969 0.779888212132595 0.779888212132595 0.779888212132595 0.57466664340579 0.779888212132595

Response to elevated platelet cytosolic Ca2+

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stxbp2 ENSMUSG00000004626 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636 0.346899083932133 0.511742979522636
Lamp2 ENSMUSG00000016534 0.0168921052924601 0.0506763158773803 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Clu ENSMUSG00000022037 0.578113371816017 0.853372965654504 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Ahsg ENSMUSG00000022868 0.397384062266614 0.397384062266614 0.347639524025037 0.397384062266614 0.299349060054895 0.397384062266614
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Pros1 ENSMUSG00000022912 0.926441990075769 0.926441990075769 0.45596561163947 0.683948417459205 0.0969812105731561 0.290943631719468
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Fermt3 ENSMUSG00000024965 0.0443599545252852 0.133079863575856 0.853372965654504 0.853372965654504 0.348008842235184 0.522013263352777
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cyb5r1 ENSMUSG00000026456 0.044737329683373 0.134211989050119 0.5155648232968 0.7733472349452 0.853049270252403 0.853049270252403
Stxbp3a ENSMUSG00000027882 0.926550375688041 0.926550375688041 0.121155015244363 0.363465045733089 0.453570536021945 0.680355804032917
Pcdh7 ENSMUSG00000029108 0.0441715176243983 0.132514552873195 0.216214347033995 0.324321520550992 0.346527959006435 0.346527959006435
Ppbp ENSMUSG00000029372 0.214037080764326 0.214037080764326 0.0449262652924809 0.134778795877443 0.0969812105731562 0.145471815859734
Pf4 ENSMUSG00000029373 0.399548817627028 0.454600801949285 0.454600801949285 0.454600801949285 0.0583853430099096 0.175156029029729
Cd9 ENSMUSG00000030342 0.0434194723707708 0.130258417112313 0.180293335960318 0.270440003940477 0.575824878403157 0.575824878403157
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Gas6 ENSMUSG00000031451 0.7802108304765 1 1 1 0.214037080764326 0.642111242292977
Aplp2 ENSMUSG00000031996 0.851061028660105 0.851061028660105 0.707899741868332 0.851061028660105 0.293293089483362 0.851061028660105
Fgb ENSMUSG00000033831 0.640861491578951 0.640861491578951 0.255901190956604 0.640861491578951 0.511742979522636 0.640861491578951
Endod1 ENSMUSG00000037419 0.513026869856283 0.513026869856283 0.511742979522636 0.513026869856283 0.148772260628989 0.446316781886968
F13a1 ENSMUSG00000039109 0.853801250889739 0.853801250889739 0.347639524025037 0.521459286037555 0.300095920620218 0.521459286037555
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831

Regulation of insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacnb3 ENSMUSG00000003352 0.452880492349546 0.577259514257969 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Gnaq ENSMUSG00000024639 0.643359829732651 0.853907737111068 0.853907737111068 0.853907737111068 0.179945789077372 0.539837367232115
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Slc2a1 ENSMUSG00000028645 0.852832278580641 0.852832278580641 0.711034989117171 0.852832278580641 0.0969812105731564 0.290943631719469
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Acsl3 ENSMUSG00000032883 0.299349060054895 0.898047180164685 1 1 0.78148726569172 1
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Kcnb1 ENSMUSG00000050556 0.398108175780842 0.578113371816017 0.346899083932133 0.578113371816017 0.578113371816017 0.578113371816017
Kcng2 ENSMUSG00000059852 0.395928178642446 0.395928178642446 0.242620429494012 0.381622160705395 0.254414773803597 0.381622160705395
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606
Kcnj11 ENSMUSG00000096146 0.395196379647461 0.5155648232968 0.5155648232968 0.5155648232968 0.348008842235184 0.5155648232968

MAPK targets/ Nuclear events mediated by MAP kinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Gnas ENSMUSG00000027523 0.779238691542963 0.779238691542963 0.450444934184774 0.675667401277161 0.17924968721805 0.537749061654149
Gnb1 ENSMUSG00000029064 1 1 0.514934023620345 0.772401035430517 0.255530331334266 0.766590994002797
Gng10 ENSMUSG00000038607 0.346899083932133 0.965039744598977 0.643359829732651 0.965039744598977 1 1
Gng2 ENSMUSG00000043004 0.393724994268831 0.400265374208515 0.400265374208515 0.400265374208515 0.208156293081417 0.400265374208515
Rapgef4 ENSMUSG00000049044 0.21549027811633 0.64647083434899 1 1 0.78148726569172 1
Kcnb1 ENSMUSG00000050556 0.398108175780842 0.578113371816017 0.346899083932133 0.578113371816017 0.578113371816017 0.578113371816017
Kcng2 ENSMUSG00000059852 0.395928178642446 0.395928178642446 0.242620429494012 0.381622160705395 0.254414773803597 0.381622160705395
Gng5 ENSMUSG00000068523 0.77858338846904 0.77858338846904 0.640355507848752 0.77858338846904 0.573498913947369 0.77858338846904
Gng3 ENSMUSG00000071658 0.926003599371282 0.926003599371282 0.776243028387552 0.926003599371282 0.291756209988535 0.875268629965606

Signaling by Interleukins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il16 ENSMUSG00000001741 0.5155648232968 0.5155648232968 0.180293335960318 0.270440003940477 0.179945789077372 0.270440003940477
Stat6 ENSMUSG00000002147 0.575536202757516 0.711034989117171 0.711034989117171 0.711034989117171 0.710001140920767 0.711034989117171
Ebi3 ENSMUSG00000003206 0.398829756175299 0.399548817627028 0.254787123615605 0.399548817627028 0.399548817627028 0.399548817627028
Hck ENSMUSG00000003283 5.62387620362729e-05 0.000168716286108819 0.216214347033995 0.216214347033995 0.0964252305385472 0.144637845807821
Dusp3 ENSMUSG00000003518 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Stxbp2 ENSMUSG00000004626 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636 0.346899083932133 0.511742979522636
Prkaca ENSMUSG00000005469 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797
Stx1a ENSMUSG00000007207 0.398108175780842 0.781170242226513 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Ppp2cb ENSMUSG00000009630 0.926441990075769 1 1 1 0.300095920620218 0.900287761860654
Sqstm1 ENSMUSG00000015837 1 1 0.852940894477647 1 0.216214347033995 0.648643041101984
Mapkapk2 ENSMUSG00000016528 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767 0.642366752097095 0.710001140920767
Map2k3 ENSMUSG00000018932 0.705752031336119 0.705752031336119 0.254414773803597 0.705752031336119 0.514617706526787 0.705752031336119
Dusp6 ENSMUSG00000019960 0.513026869856283 0.92589277149125 0.78180291566155 0.92589277149125 0.92589277149125 0.92589277149125
Mapk9 ENSMUSG00000020366 0.451840588205062 0.643359829732651 0.643359829732651 0.643359829732651 0.573498913947369 0.643359829732651
Vamp2 ENSMUSG00000020894 1 1 0.456305241393103 1 0.78180291566155 1
Syk ENSMUSG00000021457 0.0592616003460512 0.0888924005190769 0.400265374208515 0.400265374208515 0.0115535350288052 0.0346606050864156
Ywhaz ENSMUSG00000022285 0.452880492349546 0.679320738524319 0.179945789077372 0.539837367232115 0.926658283600152 0.926658283600152
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Rps6ka2 ENSMUSG00000023809 0.853372965654504 0.853372965654504 0.0588232673880149 0.176469802164045 0.204424977646738 0.306637466470107
Il33 ENSMUSG00000024810 0.346899083932133 1 1 1 0.853801250889739 1
Tollip ENSMUSG00000025139 0.779238691542963 0.779238691542963 0.337435786255283 0.506153679382925 0.180293335960318 0.506153679382925
Nfkb2 ENSMUSG00000025225 0.297095062262362 0.852940894477647 0.711034989117171 0.852940894477647 0.852940894477647 0.852940894477647
Il2ra ENSMUSG00000026770 0.447265995733381 0.853049270252403 0.853049270252403 0.853049270252403 0.780851835278818 0.853049270252403
Atf2 ENSMUSG00000027104 0.0166824765447319 0.034725083564525 0.0231500557096833 0.034725083564525 0.256271555563966 0.256271555563966
Il6ra ENSMUSG00000027947 0.254787123615605 0.382180685423408 0.455625354715449 0.455625354715449 0.0152452683068771 0.0457358049206312
Map3k7 ENSMUSG00000028284 0.853907737111068 0.853907737111068 0.514934023620345 0.772401035430517 0.514934023620344 0.772401035430517
Nfkbib ENSMUSG00000030595 0.509798138101151 0.764697207151727 0.926550375688041 0.926550375688041 0.179945789077372 0.539837367232115
Il21r ENSMUSG00000030745 0.0025036679180571 0.00751100375417131 0.299722768420014 0.44958415263002 0.78132892626786 0.78132892626786
Il4ra ENSMUSG00000030748 0.146141353215796 0.219212029823693 0.643853282854191 0.643853282854191 0.0756145297453649 0.219212029823693
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Myd88 ENSMUSG00000032508 0.92589277149125 0.926333123228344 0.926333123228344 0.926333123228344 0.398108175780842 0.926333123228344
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Psmf1 ENSMUSG00000032869 0.505838378028518 0.758757567042777 1 1 0.295581119060361 0.758757567042777
S100b ENSMUSG00000033208 0.0953125666339397 0.285937699901819 0.853049270252403 0.853049270252403 0.5155648232968 0.7733472349452
Irs2 ENSMUSG00000038894 0.0331400397096515 0.0994201191289544 0.711034989117171 0.711034989117171 0.297095062262362 0.445642593393544
Rapgef1 ENSMUSG00000039844 0.708534948098331 0.708534948098331 0.450444934184774 0.675667401277161 0.297848640636702 0.675667401277161
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Clcf1 ENSMUSG00000040663 0.454600801949285 0.454600801949285 0.299349060054895 0.449023590082343 0.0434194723707708 0.130258417112313
Ripk2 ENSMUSG00000041135 0.5155648232968 0.5155648232968 0.249907451332337 0.5155648232968 0.395928178642446 0.5155648232968
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Il20rb ENSMUSG00000044244 0.7802108304765 0.7802108304765 0.578113371816017 0.7802108304765 0.455625354715448 0.7802108304765
Mapk14 ENSMUSG00000053436 0.851732715229127 0.851732715229127 0.509798138101151 0.851732715229127 0.577259514257969 0.851732715229127
Dusp7 ENSMUSG00000053716 0.926550375688041 0.926550375688041 0.178901132102685 0.536703396308054 0.643359829732651 0.926550375688041
Ube2v1 ENSMUSG00000078923 0.711034989117171 0.781170242226513 0.781170242226513 0.781170242226513 0.45596561163947 0.781170242226513

Synthesis of PIPs at the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ocrl ENSMUSG00000001173 0.348008842235185 0.600398061312773 0.711650020253571 0.711650020253571 0.400265374208515 0.600398061312773
Rab5a ENSMUSG00000017831 0.0969812105731563 0.290943631719469 0.297848640636702 0.345037391052887 0.345037391052887 0.345037391052887
Pip4k2b ENSMUSG00000018547 0.926441990075769 1 1 1 0.45596561163947 1
Pip4k2c ENSMUSG00000025417 0.5155648232968 0.642366752097095 0.642366752097095 0.642366752097095 0.577829325134931 0.642366752097095
Pi4k2b ENSMUSG00000029186 0.120545895661627 0.270440003940477 0.180293335960318 0.270440003940477 0.853907737111068 0.853907737111068
Pik3r2 ENSMUSG00000031834 0.300095920620218 0.681901202923927 0.454600801949285 0.681901202923927 0.926550375688041 0.926550375688041
Inppl1 ENSMUSG00000032737 0.348008842235184 0.348008842235184 0.0592616003460511 0.177784801038153 0.346899083932133 0.348008842235184
Pip5k1c ENSMUSG00000034902 0.853801250889739 0.853801250889739 0.513026869856283 0.853801250889739 0.643853282854191 0.853801250889739
Mtmr9 ENSMUSG00000035078 0.454942951775342 0.682414427663012 0.711034989117171 0.711034989117171 0.148772260628989 0.446316781886967
Pik3cd ENSMUSG00000039936 0.578113371816017 0.578113371816017 0.179945789077372 0.521459286037555 0.347639524025037 0.521459286037555
Pik3r1 ENSMUSG00000041417 0.513026869856283 0.782117202022501 0.782117202022501 0.782117202022501 0.710416009055326 0.782117202022501
Pik3r6 ENSMUSG00000046207 0.853801250889739 0.853801250889739 0.5155648232968 0.853801250889739 0.711854160331342 0.853801250889739

Platelet degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Stxbp2 ENSMUSG00000004626 0.511742979522636 0.511742979522636 0.45596561163947 0.511742979522636 0.346899083932133 0.511742979522636
Lamp2 ENSMUSG00000016534 0.0168921052924601 0.0506763158773803 0.395928178642446 0.514934023620345 0.514934023620345 0.514934023620345
Calm3 ENSMUSG00000019370 1 1 0.853907737111068 1 0.578113371816017 1
Itgb3 ENSMUSG00000020689 0.78180291566155 0.78180291566155 0.710416009055326 0.78180291566155 0.5155648232968 0.78180291566155
Clu ENSMUSG00000022037 0.578113371816017 0.853372965654504 0.782117202022501 0.853372965654504 0.853372965654504 0.853372965654504
Ahsg ENSMUSG00000022868 0.397384062266614 0.397384062266614 0.347639524025037 0.397384062266614 0.299349060054895 0.397384062266614
App ENSMUSG00000022892 0.926003599371282 0.926003599371282 0.926003599371282 0.926003599371282 0.455625354715449 0.926003599371282
Pros1 ENSMUSG00000022912 0.926441990075769 0.926441990075769 0.45596561163947 0.683948417459205 0.0969812105731561 0.290943631719468
Vegfa ENSMUSG00000023951 0.0579478375430677 0.173843512629203 0.926550375688041 0.926550375688041 0.398829756175299 0.598244634262948
Fermt3 ENSMUSG00000024965 0.0443599545252852 0.133079863575856 0.853372965654504 0.853372965654504 0.348008842235184 0.522013263352777
Tuba4a ENSMUSG00000026202 0.5155648232968 0.712057867818062 0.346527959006434 0.712057867818062 0.712057867818062 0.712057867818062
Cyb5r1 ENSMUSG00000026456 0.044737329683373 0.134211989050119 0.5155648232968 0.7733472349452 0.853049270252403 0.853049270252403
Pcdh7 ENSMUSG00000029108 0.0441715176243983 0.132514552873195 0.216214347033995 0.324321520550992 0.346527959006435 0.346527959006435
Ppbp ENSMUSG00000029372 0.214037080764326 0.214037080764326 0.0449262652924809 0.134778795877443 0.0969812105731562 0.145471815859734
Pf4 ENSMUSG00000029373 0.399548817627028 0.454600801949285 0.454600801949285 0.454600801949285 0.0583853430099096 0.175156029029729
Cd9 ENSMUSG00000030342 0.0434194723707708 0.130258417112313 0.180293335960318 0.270440003940477 0.575824878403157 0.575824878403157
Figf ENSMUSG00000031380 0.781960228679124 0.781960228679124 0.577829325134931 0.781960228679124 0.643112334413352 0.781960228679124
Gas6 ENSMUSG00000031451 0.7802108304765 1 1 1 0.214037080764326 0.642111242292977
Aplp2 ENSMUSG00000031996 0.851061028660105 0.851061028660105 0.707899741868332 0.851061028660105 0.293293089483362 0.851061028660105
Fgb ENSMUSG00000033831 0.640861491578951 0.640861491578951 0.255901190956604 0.640861491578951 0.511742979522636 0.640861491578951
Endod1 ENSMUSG00000037419 0.513026869856283 0.513026869856283 0.511742979522636 0.513026869856283 0.148772260628989 0.446316781886968
F13a1 ENSMUSG00000039109 0.853801250889739 0.853801250889739 0.347639524025037 0.521459286037555 0.300095920620218 0.521459286037555
Actn4 ENSMUSG00000054808 0.393724994268831 0.393724994268831 0.11810342389482 0.354310271684459 0.344663224299303 0.393724994268831

cornsilk

Th1 and Th2 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd247 ENSMUSG00000005763 0.374407897879592 0.374407897879592 0.019509030853653 0.0562665861119851 0.0375110574079901 0.0562665861119851
Gata3 ENSMUSG00000015619 0.275387266314551 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314551 0.275387266314552
Runx3 ENSMUSG00000070691 0.506171993503726 0.57113445032749 0.57113445032749 0.57113445032749 0.0827499929192836 0.248249978757851

Th17 cell differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd247 ENSMUSG00000005763 0.374407897879592 0.374407897879592 0.019509030853653 0.0562665861119851 0.0375110574079901 0.0562665861119851
Gata3 ENSMUSG00000015619 0.275387266314551 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314551 0.275387266314552
Foxp3 ENSMUSG00000039521 0.178203013181634 0.267304519772452 0.17539708081081 0.267304519772452 0.852285566021005 0.852285566021005

cornsilk2

Spinocerebellar ataxia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Slc25a4 ENSMUSG00000031633 0.511742979522636 0.707899741868332 0.707899741868332 0.707899741868332 0.707899741868332 0.707899741868332
Opa1 ENSMUSG00000038084 0.000164597779190222 0.000493793337570666 0.256271555563966 0.384407333345949 1 1
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105
Slc25a31 ENSMUSG00000069041 0.177853449259986 0.51398322803049 0.51398322803049 0.51398322803049 0.399189600887034 0.51398322803049
Tbpl1 ENSMUSG00000071359 0.120850531362929 0.324321520550992 0.643853282854191 0.643853282854191 0.216214347033995 0.324321520550992

Proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Mitotic Metaphase and Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Downstream TCR signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd3g ENSMUSG00000002033 0.696424020390979 0.696424020390979 0.607108475097572 0.696424020390979 0.532150934397798 0.696424020390979
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Separation of Sister Chromatids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Mitotic Anaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

TCR signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd3g ENSMUSG00000002033 0.696424020390979 0.696424020390979 0.607108475097572 0.696424020390979 0.532150934397798 0.696424020390979
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Nck1 ENSMUSG00000032475 0.0168921052924601 0.0253381579386902 0.0168921052924602 0.0253381579386902 0.299349060054895 0.299349060054895
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

MAPK6/MAPK4 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Etv4 ENSMUSG00000017724 0.0969812105731562 0.290943631719469 0.573205482926791 0.705316781644051 0.705316781644051 0.705316781644051
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Cdc42ep5 ENSMUSG00000063838 0.0592616003460511 0.177784801038153 0.643359829732651 0.643359829732651 0.255530331334266 0.383295497001398
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Degradation of AXIN

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

PTEN Regulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Pml ENSMUSG00000036986 0.924286968561133 0.924286968561133 0.120545895661627 0.180818843492441 0.079673781762435 0.180818843492441
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

G2/M Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Mitotic G2-G2/M phases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Autodegradation of Cdh1 by Cdh1:APC/C

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

CLEC7A (Dectin-1) signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

APC/C:Cdc20 mediated degradation of Securin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cdc20:Phospho-APC/C mediated degradation of Cyclin A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

p53-Independent DNA Damage Response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

CDK-mediated phosphorylation and removal of Cdc6

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cross-presentation of soluble exogenous antigens (endosomes)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cellular response to hypoxia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

p53-Independent G1/S DNA damage checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of RUNX2 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Ubiquitin-dependent degradation of Cyclin D

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of PTEN stability and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

The role of GTSE1 in G2/M progression after G2 checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of ornithine decarboxylase (ODC)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Autodegradation of the E3 ubiquitin ligase COP1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Hedgehog ‘off’ state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rpgrip1l ENSMUSG00000033282 0.0583853430099097 0.0875780145148645 0.0566379395854604 0.0875780145148645 0.78180291566155 0.78180291566155
Wdr35 ENSMUSG00000066643 0.00276975149305652 0.00830925447916957 0.023800255149993 0.0357003827249895 0.255901190956604 0.255901190956604
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Degradation of beta-catenin by the destruction complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cell Cycle Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of RUNX3 expression and activity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Stabilization of p53

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Metabolism of polyamines

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of mRNA stability by proteins that bind AU-rich elements

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Exosc2 ENSMUSG00000039356 0.637274134311157 0.637274134311157 0.255901190956604 0.637274134311157 0.514934023620345 0.637274134311157
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Ub-specific processing proteases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Usp33 ENSMUSG00000025437 0.0449262652924809 0.134778795877443 0.400265374208515 0.600398061312773 0.926441990075769 0.926441990075769
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Usp14 ENSMUSG00000047879 0.180293335960318 0.323235417174495 0.21549027811633 0.323235417174495 0.642366752097095 0.642366752097095
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

FBXL7 down-regulates AURKA during mitotic entry and in early mitosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

NIK–>noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Degradation of DVL

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Degradation of GLI1 by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

GLI3 is processed to GLI3R by the proteasome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Dectin-1 mediated noncanonical NF-kB signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

C-type lectin receptors (CLRs)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

CDT1 association with the CDC6:ORC:origin complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

AUF1 (hnRNP D0) binds and destabilizes mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cellular responses to stress

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nprl2 ENSMUSG00000010057 0.642366752097095 0.853480389728993 0.513665062682276 0.853480389728993 0.853480389728993 0.853480389728993
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Actr10 ENSMUSG00000021076 0.346527959006435 0.514300775319626 0.348008842235184 0.514300775319626 0.514300775319626 0.514300775319626
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Dctn5 ENSMUSG00000030868 0.21549027811633 0.323235417174495 0.120545895661628 0.323235417174495 0.849457568495547 0.849457568495547
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Dnaja2 ENSMUSG00000031701 0.255530331334266 0.383295497001398 0.0761127945805735 0.228338383741721 0.398469281729516 0.398469281729516
Hsbp1 ENSMUSG00000031839 0.453225835454266 0.641867098978198 0.0969812105731564 0.290943631719469 0.641867098978198 0.641867098978198
Atp6v1h ENSMUSG00000033793 0.513665062682276 0.707899741868332 0.0953125666339397 0.285937699901819 0.707899741868332 0.707899741868332
B630005N14Rik ENSMUSG00000042742 0.148772260628989 0.446316781886968 0.399548817627028 0.599323226440542 0.926003599371282 0.926003599371282
Atp6v1a ENSMUSG00000052459 0.0168921052924601 0.0506763158773803 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of mitotic cell cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cellular responses to external stimuli

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nprl2 ENSMUSG00000010057 0.642366752097095 0.853480389728993 0.513665062682276 0.853480389728993 0.853480389728993 0.853480389728993
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Actr10 ENSMUSG00000021076 0.346527959006435 0.514300775319626 0.348008842235184 0.514300775319626 0.514300775319626 0.514300775319626
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Dctn5 ENSMUSG00000030868 0.21549027811633 0.323235417174495 0.120545895661628 0.323235417174495 0.849457568495547 0.849457568495547
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Dnaja2 ENSMUSG00000031701 0.255530331334266 0.383295497001398 0.0761127945805735 0.228338383741721 0.398469281729516 0.398469281729516
Hsbp1 ENSMUSG00000031839 0.453225835454266 0.641867098978198 0.0969812105731564 0.290943631719469 0.641867098978198 0.641867098978198
Atp6v1h ENSMUSG00000033793 0.513665062682276 0.707899741868332 0.0953125666339397 0.285937699901819 0.707899741868332 0.707899741868332
B630005N14Rik ENSMUSG00000042742 0.148772260628989 0.446316781886968 0.399548817627028 0.599323226440542 0.926003599371282 0.926003599371282
Atp6v1a ENSMUSG00000052459 0.0168921052924601 0.0506763158773803 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

APC/C-mediated degradation of cell cycle proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

SCF(Skp2)-mediated degradation of p27/p21

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

PIP3 activates AKT signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Pml ENSMUSG00000036986 0.924286968561133 0.924286968561133 0.120545895661627 0.180818843492441 0.079673781762435 0.180818843492441
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Activation of NF-kappaB in B cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Asymmetric localization of PCP proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Switching of origins to a post-replicative state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Transcriptional regulation by RUNX2

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Hedgehog ligand biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Association of TriC/CCT with target proteins during biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cct4 ENSMUSG00000007739 0.0331400397096515 0.0994201191289544 0.249907451332337 0.374861176998506 1 1
Cct5 ENSMUSG00000022234 0.294820734456232 0.852175490580835 0.573791743469336 0.852175490580835 0.852175490580835 0.852175490580835
Cct8 ENSMUSG00000025613 0.178901132102685 0.536703396308055 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767

M Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

p53-Dependent G1 DNA Damage Response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Antigen processing-Cross presentation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Sec22b ENSMUSG00000027879 0.295581119060361 0.711854160331342 0.513665062682276 0.711854160331342 0.711854160331342 0.711854160331342
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

p53-Dependent G1/S DNA damage checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Regulation of RAS by GAPs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

RUNX1 regulates transcription of genes involved in differentiation of HSCs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Assembly of the pre-replicative complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

G1/S DNA Damage Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Deubiquitination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Usp33 ENSMUSG00000025437 0.0449262652924809 0.134778795877443 0.400265374208515 0.600398061312773 0.926441990075769 0.926441990075769
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Usp14 ENSMUSG00000047879 0.180293335960318 0.323235417174495 0.21549027811633 0.323235417174495 0.642366752097095 0.642366752097095
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Orc1 removal from chromatin

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cyclin E associated events during G1/S transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Intracellular signaling by second messengers

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Pml ENSMUSG00000036986 0.924286968561133 0.924286968561133 0.120545895661627 0.180818843492441 0.079673781762435 0.180818843492441
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cyclin A:Cdk2-associated events at S phase entry

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Downstream signaling events of B Cell Receptor (BCR)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Signaling by Hedgehog

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rpgrip1l ENSMUSG00000033282 0.0583853430099097 0.0875780145148645 0.0566379395854604 0.0875780145148645 0.78180291566155 0.78180291566155
Wdr35 ENSMUSG00000066643 0.00276975149305652 0.00830925447916957 0.023800255149993 0.0357003827249895 0.255901190956604 0.255901190956604
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

G1/S Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

S Phase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Esco2 ENSMUSG00000022034 0.0583853430099098 0.144637845807821 0.711034989117171 0.711034989117171 0.0964252305385473 0.144637845807821
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Neddylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Ercc8 ENSMUSG00000021694 0.577829325134931 0.577829325134931 0.180293335960318 0.540880007880955 0.45596561163947 0.577829325134931
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Dcun1d5 ENSMUSG00000032002 0.576973746230333 0.576973746230333 0.300095920620218 0.576973746230333 0.511097249598474 0.576973746230333
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Transcriptional regulation by RUNX3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Cell Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Esco2 ENSMUSG00000022034 0.0583853430099098 0.144637845807821 0.711034989117171 0.711034989117171 0.0964252305385473 0.144637845807821
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Nop10 ENSMUSG00000027133 1 1 0.179945789077372 0.539837367232115 0.642366752097095 0.963550128145642
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

TCF dependent signaling in response to WNT

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Class I MHC mediated antigen processing & presentation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcap31 ENSMUSG00000002015 0.711240436189781 0.711240436189781 0.344663224299303 0.711240436189781 0.643853282854191 0.711240436189781
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Sec23a ENSMUSG00000020986 0.00463747559282087 0.0139124267784626 0.455625354715449 0.45596561163947 0.45596561163947 0.45596561163947
Pja2 ENSMUSG00000024083 0.0334587898203823 0.100376369461147 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Sec22b ENSMUSG00000027879 0.295581119060361 0.711854160331342 0.513665062682276 0.711854160331342 0.711854160331342 0.711854160331342
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Siah1a ENSMUSG00000036840 0.180293335960318 0.25141795904251 0.213307944885796 0.25141795904251 0.25141795904251 0.25141795904251
Rnf14 ENSMUSG00000060450 0.0761127945805735 0.180818843492441 0.120545895661628 0.180818843492441 0.643853282854191 0.643853282854191
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Synthesis of DNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

DNA Replication Pre-Initiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Hedgehog ‘on’ state

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Metabolism of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cct4 ENSMUSG00000007739 0.0331400397096515 0.0994201191289544 0.249907451332337 0.374861176998506 1 1
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Ppa1 ENSMUSG00000020089 0.21549027811633 0.323235417174495 0.0766111619812296 0.229833485943689 0.853801250889739 0.853801250889739
Sec23a ENSMUSG00000020986 0.00463747559282087 0.0139124267784626 0.455625354715449 0.45596561163947 0.45596561163947 0.45596561163947
Actr10 ENSMUSG00000021076 0.346527959006435 0.514300775319626 0.348008842235184 0.514300775319626 0.514300775319626 0.514300775319626
Ercc8 ENSMUSG00000021694 0.577829325134931 0.577829325134931 0.180293335960318 0.540880007880955 0.45596561163947 0.577829325134931
Cct5 ENSMUSG00000022234 0.294820734456232 0.852175490580835 0.573791743469336 0.852175490580835 0.852175490580835 0.852175490580835
Usp33 ENSMUSG00000025437 0.0449262652924809 0.134778795877443 0.400265374208515 0.600398061312773 0.926441990075769 0.926441990075769
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Cct8 ENSMUSG00000025613 0.178901132102685 0.536703396308055 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Mrrf ENSMUSG00000026887 0.782117202022501 0.782117202022501 0.21549027811633 0.64647083434899 0.78180291566155 0.782117202022501
Sec22b ENSMUSG00000027879 0.295581119060361 0.711854160331342 0.513665062682276 0.711854160331342 0.711854160331342 0.711854160331342
Reck ENSMUSG00000028476 0.0312459040565944 0.0937377121697832 1 1 1 1
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Pigg ENSMUSG00000029263 0.250285839267991 0.338976281569376 0.338976281569376 0.338976281569376 0.338592117141989 0.338976281569376
Dctn5 ENSMUSG00000030868 0.21549027811633 0.323235417174495 0.120545895661628 0.323235417174495 0.849457568495547 0.849457568495547
Atp6ap2 ENSMUSG00000031007 0.253294730253594 0.379942095380391 0.120850531362929 0.362551594088788 0.453570536021945 0.453570536021945
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Dcun1d5 ENSMUSG00000032002 0.576973746230333 0.576973746230333 0.300095920620218 0.576973746230333 0.511097249598474 0.576973746230333
Mrpl34 ENSMUSG00000034880 0.45596561163947 0.781170242226513 0.781170242226513 0.781170242226513 0.642864324224729 0.781170242226513
Pml ENSMUSG00000036986 0.924286968561133 0.924286968561133 0.120545895661627 0.180818843492441 0.079673781762435 0.180818843492441
Pigu ENSMUSG00000038383 0.0162664168407233 0.0487992505221699 1 1 0.578113371816017 0.867170057724026
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Asgr2 ENSMUSG00000040963 0.243783464125984 0.24724444175385 0.0038031455224948 0.0114094365674844 0.24724444175385 0.24724444175385
Usp14 ENSMUSG00000047879 0.180293335960318 0.323235417174495 0.21549027811633 0.323235417174495 0.642366752097095 0.642366752097095
Mrpl35 ENSMUSG00000052962 0.121155015244363 0.363465045733089 0.348008842235184 0.522013263352777 1 1
Ero1lb ENSMUSG00000057069 0.216214347033994 0.648643041101983 0.45596561163947 0.683948417459205 1 1
Nsmce2 ENSMUSG00000059586 0.392243127063687 0.590587491403246 0.708534948098331 0.708534948098331 0.393724994268831 0.590587491403246
Wdr61 ENSMUSG00000061559 0.641867098978197 0.924987846321933 0.924987846321933 0.924987846321933 0.509798138101151 0.924987846321933
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105
Trappc2 ENSMUSG00000079317 0.214764523938594 0.323235417174495 0.21549027811633 0.323235417174495 0.575824878403157 0.575824878403157

Cilium Assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cct4 ENSMUSG00000007739 0.0331400397096515 0.0994201191289544 0.249907451332337 0.374861176998506 1 1
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Cct5 ENSMUSG00000022234 0.294820734456232 0.852175490580835 0.573791743469336 0.852175490580835 0.852175490580835 0.852175490580835
Cct8 ENSMUSG00000025613 0.178901132102685 0.536703396308055 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Rpgrip1l ENSMUSG00000033282 0.0583853430099097 0.0875780145148645 0.0566379395854604 0.0875780145148645 0.78180291566155 0.78180291566155
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Wdr35 ENSMUSG00000066643 0.00276975149305652 0.00830925447916957 0.023800255149993 0.0357003827249895 0.255901190956604 0.255901190956604
Ttc30a2 ENSMUSG00000075272 0.45596561163947 0.576973746230334 0.254787123615605 0.576973746230334 0.576973746230334 0.576973746230334

Cell Cycle, Mitotic

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Esco2 ENSMUSG00000022034 0.0583853430099098 0.144637845807821 0.711034989117171 0.711034989117171 0.0964252305385473 0.144637845807821
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

DNA Replication

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

PCP/CE pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Interleukin-1 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Mitotic G1 phase and G1/S transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

UCH proteinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

TNFR2 non-canonical NF-kB pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

ABC-family proteins mediated transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

FCERI mediated NF-kB activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Organelle biogenesis and maintenance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cct4 ENSMUSG00000007739 0.0331400397096515 0.0994201191289544 0.249907451332337 0.374861176998506 1 1
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Cct5 ENSMUSG00000022234 0.294820734456232 0.852175490580835 0.573791743469336 0.852175490580835 0.852175490580835 0.852175490580835
Cct8 ENSMUSG00000025613 0.178901132102685 0.536703396308055 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Rpgrip1l ENSMUSG00000033282 0.0583853430099097 0.0875780145148645 0.0566379395854604 0.0875780145148645 0.78180291566155 0.78180291566155
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927
Wdr35 ENSMUSG00000066643 0.00276975149305652 0.00830925447916957 0.023800255149993 0.0357003827249895 0.255901190956604 0.255901190956604
Ttc30a2 ENSMUSG00000075272 0.45596561163947 0.576973746230334 0.254787123615605 0.576973746230334 0.576973746230334 0.576973746230334

Mitotic Spindle Checkpoint

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513

Interleukin-1 family signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Mitotic Prometaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Haus2 ENSMUSG00000027285 0.21549027811633 0.646470834348989 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Cdk5rap2 ENSMUSG00000039298 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.454600801949285 0.681901202923927

BBSome-mediated cargo-targeting to cilium

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cct4 ENSMUSG00000007739 0.0331400397096515 0.0994201191289544 0.249907451332337 0.374861176998506 1 1
Cct5 ENSMUSG00000022234 0.294820734456232 0.852175490580835 0.573791743469336 0.852175490580835 0.852175490580835 0.852175490580835
Cct8 ENSMUSG00000025613 0.178901132102685 0.536703396308055 0.643359829732651 0.710001140920767 0.710001140920767 0.710001140920767

Resolution of Sister Chromatid Cohesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739

Antigen processing: Ubiquitination & Proteasome degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pja2 ENSMUSG00000024083 0.0334587898203823 0.100376369461147 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Siah1a ENSMUSG00000036840 0.180293335960318 0.25141795904251 0.213307944885796 0.25141795904251 0.25141795904251 0.25141795904251
Rnf14 ENSMUSG00000060450 0.0761127945805735 0.180818843492441 0.120545895661628 0.180818843492441 0.643853282854191 0.643853282854191
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Amino acids regulate mTORC1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nprl2 ENSMUSG00000010057 0.642366752097095 0.853480389728993 0.513665062682276 0.853480389728993 0.853480389728993 0.853480389728993
Atp6v1h ENSMUSG00000033793 0.513665062682276 0.707899741868332 0.0953125666339397 0.285937699901819 0.707899741868332 0.707899741868332
B630005N14Rik ENSMUSG00000042742 0.148772260628989 0.446316781886968 0.399548817627028 0.599323226440542 0.926003599371282 0.926003599371282
Atp6v1a ENSMUSG00000052459 0.0168921052924601 0.0506763158773803 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969

Cellular response to starvation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nprl2 ENSMUSG00000010057 0.642366752097095 0.853480389728993 0.513665062682276 0.853480389728993 0.853480389728993 0.853480389728993
Atp6v1h ENSMUSG00000033793 0.513665062682276 0.707899741868332 0.0953125666339397 0.285937699901819 0.707899741868332 0.707899741868332
B630005N14Rik ENSMUSG00000042742 0.148772260628989 0.446316781886968 0.399548817627028 0.599323226440542 0.926003599371282 0.926003599371282
Atp6v1a ENSMUSG00000052459 0.0168921052924601 0.0506763158773803 0.576973746230334 0.577259514257969 0.577259514257969 0.577259514257969

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513

Amplification of signal from the kinetochores

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513

G2/M Checkpoints

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ccnb2 ENSMUSG00000032218 0.643359829732651 0.853801250889739 0.514934023620345 0.853801250889739 0.853801250889739 0.853801250889739
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Adaptive Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcap31 ENSMUSG00000002015 0.711240436189781 0.711240436189781 0.344663224299303 0.711240436189781 0.643853282854191 0.711240436189781
Cd3g ENSMUSG00000002033 0.696424020390979 0.696424020390979 0.607108475097572 0.696424020390979 0.532150934397798 0.696424020390979
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Sec23a ENSMUSG00000020986 0.00463747559282087 0.0139124267784626 0.455625354715449 0.45596561163947 0.45596561163947 0.45596561163947
Actr10 ENSMUSG00000021076 0.346527959006435 0.514300775319626 0.348008842235184 0.514300775319626 0.514300775319626 0.514300775319626
Pja2 ENSMUSG00000024083 0.0334587898203823 0.100376369461147 0.216214347033995 0.324321520550992 0.78180291566155 0.78180291566155
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Sec22b ENSMUSG00000027879 0.295581119060361 0.711854160331342 0.513665062682276 0.711854160331342 0.711854160331342 0.711854160331342
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Dctn5 ENSMUSG00000030868 0.21549027811633 0.323235417174495 0.120545895661628 0.323235417174495 0.849457568495547 0.849457568495547
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Nck1 ENSMUSG00000032475 0.0168921052924601 0.0253381579386902 0.0168921052924602 0.0253381579386902 0.299349060054895 0.299349060054895
Siah1a ENSMUSG00000036840 0.180293335960318 0.25141795904251 0.213307944885796 0.25141795904251 0.25141795904251 0.25141795904251
Rnf14 ENSMUSG00000060450 0.0761127945805735 0.180818843492441 0.120545895661628 0.180818843492441 0.643853282854191 0.643853282854191
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Signaling by Interleukins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Crk ENSMUSG00000017776 0.120850531362929 0.362551594088788 0.643853282854191 0.643853282854191 0.400265374208515 0.600398061312773
Brwd1 ENSMUSG00000022914 0.704220158648919 0.704220158648919 0.0969812105731561 0.290943631719468 0.397384062266614 0.596076093399921
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Beta-catenin independent WNT signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Fc epsilon receptor (FCERI) signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

Signaling by Rho GTPases, Miro GTPases and RHOBTB3

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Nck1 ENSMUSG00000032475 0.0168921052924601 0.0253381579386902 0.0168921052924602 0.0253381579386902 0.299349060054895 0.299349060054895
Arhgap33 ENSMUSG00000036882 0.252920381501206 0.37938057225181 0.853480389728993 0.853480389728993 0.213307944885796 0.37938057225181
Arhgef37 ENSMUSG00000045094 0.853694531487825 0.853694531487825 0.254414773803597 0.599323226440542 0.399548817627028 0.599323226440542
Wipf1 ENSMUSG00000075284 0.924872384323464 0.924872384323464 0.120545895661628 0.361637686984883 0.454942951775342 0.682414427663012

Signaling by Rho GTPases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Pdpk1 ENSMUSG00000024122 0.0162664168407233 0.0487992505221699 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Nck1 ENSMUSG00000032475 0.0168921052924601 0.0253381579386902 0.0168921052924602 0.0253381579386902 0.299349060054895 0.299349060054895
Arhgap33 ENSMUSG00000036882 0.252920381501206 0.37938057225181 0.853480389728993 0.853480389728993 0.213307944885796 0.37938057225181
Arhgef37 ENSMUSG00000045094 0.853694531487825 0.853694531487825 0.254414773803597 0.599323226440542 0.399548817627028 0.599323226440542
Wipf1 ENSMUSG00000075284 0.924872384323464 0.924872384323464 0.120545895661628 0.361637686984883 0.454942951775342 0.682414427663012

Post-translational protein modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Rhot1 ENSMUSG00000017686 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334 0.455625354715449 0.576973746230334
Ube2d1 ENSMUSG00000019927 0.642366752097095 0.642366752097095 0.398108175780842 0.642366752097095 0.452880492349546 0.642366752097095
Sec23a ENSMUSG00000020986 0.00463747559282087 0.0139124267784626 0.455625354715449 0.45596561163947 0.45596561163947 0.45596561163947
Actr10 ENSMUSG00000021076 0.346527959006435 0.514300775319626 0.348008842235184 0.514300775319626 0.514300775319626 0.514300775319626
Ercc8 ENSMUSG00000021694 0.577829325134931 0.577829325134931 0.180293335960318 0.540880007880955 0.45596561163947 0.577829325134931
Usp33 ENSMUSG00000025437 0.0449262652924809 0.134778795877443 0.400265374208515 0.600398061312773 0.926441990075769 0.926441990075769
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Sec22b ENSMUSG00000027879 0.295581119060361 0.711854160331342 0.513665062682276 0.711854160331342 0.711854160331342 0.711854160331342
Reck ENSMUSG00000028476 0.0312459040565944 0.0937377121697832 1 1 1 1
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Pigg ENSMUSG00000029263 0.250285839267991 0.338976281569376 0.338976281569376 0.338976281569376 0.338592117141989 0.338976281569376
Dctn5 ENSMUSG00000030868 0.21549027811633 0.323235417174495 0.120545895661628 0.323235417174495 0.849457568495547 0.849457568495547
Rbbp7 ENSMUSG00000031353 0.711240436189781 0.711240436189781 0.0964252305385472 0.289275691615642 0.348008842235184 0.522013263352776
Dcun1d5 ENSMUSG00000032002 0.576973746230333 0.576973746230333 0.300095920620218 0.576973746230333 0.511097249598474 0.576973746230333
Pml ENSMUSG00000036986 0.924286968561133 0.924286968561133 0.120545895661627 0.180818843492441 0.079673781762435 0.180818843492441
Pigu ENSMUSG00000038383 0.0162664168407233 0.0487992505221699 1 1 0.578113371816017 0.867170057724026
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Asgr2 ENSMUSG00000040963 0.243783464125984 0.24724444175385 0.0038031455224948 0.0114094365674844 0.24724444175385 0.24724444175385
Usp14 ENSMUSG00000047879 0.180293335960318 0.323235417174495 0.21549027811633 0.323235417174495 0.642366752097095 0.642366752097095
Nsmce2 ENSMUSG00000059586 0.392243127063687 0.590587491403246 0.708534948098331 0.708534948098331 0.393724994268831 0.590587491403246
Wdr61 ENSMUSG00000061559 0.641867098978197 0.924987846321933 0.924987846321933 0.924987846321933 0.509798138101151 0.924987846321933
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105
Trappc2 ENSMUSG00000079317 0.214764523938594 0.323235417174495 0.21549027811633 0.323235417174495 0.575824878403157 0.575824878403157

Signaling by WNT

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Rnf146 ENSMUSG00000038876 0.0969812105731561 0.290943631719468 0.853801250889739 0.926333123228344 0.926333123228344 0.926333123228344
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

MAPK family signaling cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psma2 ENSMUSG00000015671 0.925613508363027 0.92616891281798 0.255901190956604 0.767703572869812 0.92616891281798 0.92616891281798
Etv4 ENSMUSG00000017724 0.0969812105731562 0.290943631719469 0.573205482926791 0.705316781644051 0.705316781644051 0.705316781644051
Psmd13 ENSMUSG00000025487 0.780851835278817 0.780851835278817 0.640861491578951 0.780851835278817 0.642366752097095 0.780851835278817
Psmb7 ENSMUSG00000026750 0.453225835454266 0.681901202923927 0.708534948098331 0.708534948098331 0.454600801949285 0.681901202923927
Psmd5 ENSMUSG00000026869 0.0566379395854603 0.169913818756381 0.640861491578951 0.640861491578951 0.295581119060361 0.443371678590541
Psmc2 ENSMUSG00000028932 0.346527959006435 0.600398061312773 0.400265374208515 0.600398061312773 0.926333123228344 0.926333123228344
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513
Cdc42ep5 ENSMUSG00000063838 0.0592616003460511 0.177784801038153 0.643359829732651 0.643359829732651 0.255530331334266 0.383295497001398
Psma5 ENSMUSG00000068749 0.777255087907932 0.851061028660105 0.297848640636702 0.851061028660105 0.851061028660105 0.851061028660105

EML4 and NUDC in mitotic spindle formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zwint ENSMUSG00000019923 0.0756145297453648 0.179446626251387 0.119631084167592 0.179446626251387 0.92589277149125 0.92589277149125
Pafah1b1 ENSMUSG00000020745 0.0969812105731564 0.270440003940477 0.180293335960318 0.270440003940477 0.853049270252403 0.853049270252403
Dsn1 ENSMUSG00000027635 0.395928178642446 0.593892267963669 0.214037080764326 0.593892267963669 0.708745765211584 0.708745765211584
Itgb3bp ENSMUSG00000028549 0.78180291566155 0.78180291566155 0.144820068500793 0.264150874616835 0.17610058307789 0.264150874616835
Ppp2r1b ENSMUSG00000032058 0.0110666956860337 0.0332000870581011 0.17750354896016 0.26625532344024 0.781170242226513 0.781170242226513

darkolivegreen2

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Gmpr ENSMUSG00000000253 0.344663224299303 0.643853282854191 0.514300775319626 0.643853282854191 0.643853282854191 0.643853282854191
Comt ENSMUSG00000000326 0.249907451332337 0.508817043656047 0.43283647035887 0.508817043656047 0.508817043656047 0.508817043656047
Ckb ENSMUSG00000001270 0.113498953177704 0.340496859533111 0.57466664340579 0.57466664340579 0.445116333668945 0.57466664340579
Gstt3 ENSMUSG00000001665 0.334323804341915 0.501485706512872 0.847317797849051 0.847317797849051 0.110102998658251 0.330308995974752
Uck1 ENSMUSG00000002550 0.348008842235184 1 0.926003599371282 1 1 1
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Eno2 ENSMUSG00000004267 0.576973746230334 0.710208797518812 0.710208797518812 0.710208797518812 0.577259514257969 0.710208797518812
Atp6v1f ENSMUSG00000004285 0.573498913947369 0.573498913947369 0.451840588205062 0.573498913947369 0.511097249598474 0.573498913947369
Lbr ENSMUSG00000004880 0.852940894477647 0.852940894477647 0.347639524025037 0.852940894477647 0.710001140920767 0.852940894477647
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Shpk ENSMUSG00000005951 0.179945789077372 0.539837367232115 0.643359829732651 0.643359829732651 0.453225835454266 0.643359829732651
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Aprt ENSMUSG00000006589 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152 0.853694531487825 0.926658283600152
Cers4 ENSMUSG00000008206 0.710001140920767 0.710001140920767 0.0432318933800775 0.129695680140232 0.299349060054896 0.449023590082344
Fut1 ENSMUSG00000008461 0.232742460142726 0.232742460142726 0.232742460142726 0.232742460142726 0.00483879841783549 0.0145163952535065
Atp6v0d1 ENSMUSG00000013160 0.509144723230069 0.562539849036184 0.562539849036184 0.562539849036184 0.343537039781257 0.562539849036184
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Ehmt2 ENSMUSG00000013787 0.0756145297453649 0.226843589236095 0.711854160331342 0.711854160331342 0.454600801949285 0.681901202923927
Pigl ENSMUSG00000014245 0.449743164679353 0.710208797518812 0.710208797518812 0.710208797518812 0.63856761373451 0.710208797518812
Lta4h ENSMUSG00000015889 0.709375484777034 0.926333123228344 0.642864324224729 0.926333123228344 0.926333123228344 0.926333123228344
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Acadvl ENSMUSG00000018574 0.348008842235184 0.926003599371281 0.780851835278817 0.926003599371281 0.926003599371281 0.926003599371281
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Atp6ap1 ENSMUSG00000019087 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.120850531362929 0.362551594088788
Mdh2 ENSMUSG00000019179 0.708534948098331 0.708745765211584 0.447621891168214 0.708745765211584 0.708745765211584 0.708745765211584
Echdc1 ENSMUSG00000019883 0.0334587898203823 0.100376369461147 0.344663224299303 0.344663224299303 0.147458757705094 0.221188136557642
Gamt ENSMUSG00000020150 0.148115998140416 0.222173997210623 0.0230207752632622 0.0690623257897866 0.511742979522636 0.511742979522636
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Mgat1 ENSMUSG00000020346 0.0240620856673909 0.0721862570021728 0.711854160331342 1 1 1
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Galk1 ENSMUSG00000020766 0.254414773803597 0.450143880930326 0.578113371816017 0.578113371816017 0.300095920620217 0.450143880930326
Plcd3 ENSMUSG00000020937 0.119631084167592 0.179446626251388 0.710416009055326 0.710416009055326 0.0964252305385472 0.179446626251388
Coq6 ENSMUSG00000021235 0.782117202022501 0.782117202022501 0.297095062262363 0.767614469283954 0.511742979522636 0.767614469283954
Ptdss1 ENSMUSG00000021518 0.640861491578951 0.640861491578951 0.044926265292481 0.134778795877443 0.345037391052887 0.51755608657933
Ephx2 ENSMUSG00000022040 0.0958690133561599 0.28760704006848 0.853801250889739 0.853801250889739 0.575824878403157 0.853801250889739
Gm21685 ENSMUSG00000022066 0.511742979522636 0.767614469283954 0.178901132102685 0.536703396308054 0.7802108304765 0.7802108304765
Amacr ENSMUSG00000022244 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041 0.7802108304765 0.926550375688041
Aco2 ENSMUSG00000022477 0.33116978622016 0.49675467933024 0.578113371816017 0.578113371816017 0.168646652367079 0.49675467933024
Gpt ENSMUSG00000022546 0.214764523938594 0.644293571815782 0.641867098978198 0.78148726569172 0.78148726569172 0.78148726569172
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Gpaa1 ENSMUSG00000022561 0.146141353215796 0.438424059647387 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Oplah ENSMUSG00000022562 0.18064054691103 0.541921640733091 0.511742979522636 0.711240436189781 0.711240436189781 0.711240436189781
Naprt1 ENSMUSG00000022574 0.45596561163947 0.683948417459205 0.148772260628989 0.446316781886968 0.853907737111068 0.853907737111068
Csad ENSMUSG00000023044 0.0763619660358787 0.229085898107636 0.254414773803597 0.381622160705395 1 1
Hagh ENSMUSG00000024158 0.711034989117171 0.711034989117171 0.642864324224729 0.711034989117171 0.5155648232968 0.711034989117171
Cndp2 ENSMUSG00000024644 0.777255087907932 0.777255087907932 0.576973746230334 0.777255087907932 0.505169133438821 0.777255087907932
Pi4k2a ENSMUSG00000025178 0.297095062262362 0.445642593393544 0.707899741868332 0.707899741868332 0.0746183450292887 0.223855035087866
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Sirt3 ENSMUSG00000025486 0.639337105615665 0.779238691542963 0.779238691542963 0.779238691542963 0.453570536021945 0.779238691542963
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ptdss2 ENSMUSG00000025495 0.297848640636702 0.578113371816017 0.578113371816017 0.578113371816017 0.45596561163947 0.578113371816017
Taldo1 ENSMUSG00000025503 0.300095920620218 0.900287761860654 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Hadha ENSMUSG00000025745 0.299349060054895 0.898047180164686 1 1 0.78148726569172 1
Pde6d ENSMUSG00000026239 0.778911768167544 0.778911768167544 0.514300775319626 0.778911768167544 0.577259514257969 0.778911768167544
Pycr2 ENSMUSG00000026520 0.511097249598474 0.643853282854191 0.643853282854191 0.643853282854191 0.637274134311157 0.643853282854191
Prdx6 ENSMUSG00000026701 0.0443599545252853 0.133079863575856 0.78148726569172 0.78148726569172 0.707899741868332 0.78148726569172
Ptges2 ENSMUSG00000026820 0.710001140920767 0.710001140920767 0.710001140920767 0.710001140920767 0.573498913947369 0.710001140920767
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Uap1l1 ENSMUSG00000026956 0.342026805366747 0.51304020805012 0.514300775319626 0.514300775319626 0.253294730253595 0.51304020805012
Pla2g12a ENSMUSG00000027999 0.256271555563966 0.384407333345949 0.78180291566155 0.78180291566155 0.0964252305385474 0.289275691615642
Alad ENSMUSG00000028393 0.246861959455465 0.370292939183197 0.57113445032749 0.57113445032749 0.118409250205154 0.355227750615461
Gba2 ENSMUSG00000028467 0.0743693776059065 0.223108132817719 0.255530331334266 0.383295497001398 0.45596561163947 0.45596561163947
Gne ENSMUSG00000028479 0.777255087907932 0.777255087907932 0.569937449249116 0.777255087907932 0.0441715176243983 0.132514552873195
Ctps ENSMUSG00000028633 0.641867098978198 0.641867098978198 0.17610058307789 0.52830174923367 0.398829756175299 0.598244634262948
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Gale ENSMUSG00000028671 0.118409250205154 0.355227750615461 0.851732715229127 0.851732715229127 0.643359829732651 0.851732715229127
Hmgcl ENSMUSG00000028672 0.398108175780842 0.926550375688041 0.926550375688041 0.926550375688041 0.707899741868332 0.926550375688041
Akr1a1 ENSMUSG00000028692 0.576973746230334 0.576973746230334 0.344663224299303 0.51755608657933 0.345037391052887 0.51755608657933
Cmpk1 ENSMUSG00000028719 0.00768144932639892 0.0230443479791968 0.711650020253571 0.711650020253571 0.213307944885796 0.319961917328694
Aldh4a1 ENSMUSG00000028737 0.45596561163947 0.45596561163947 0.213307944885796 0.383851786434905 0.255901190956604 0.383851786434905
Ddost ENSMUSG00000028757 0.640861491578951 0.640861491578951 0.397384062266614 0.640861491578951 0.509144723230069 0.640861491578951
Ak2 ENSMUSG00000028792 0.576973746230334 1 1 1 0.781170242226513 1
Nadk ENSMUSG00000029063 0.453225835454266 0.573791743469336 0.509144723230069 0.573791743469336 0.573791743469336 0.573791743469336
Pgm1 ENSMUSG00000029171 0.0116356061791785 0.0349068185375355 0.0451153644990945 0.0676730467486417 0.255901190956604 0.255901190956604
Lias ENSMUSG00000029199 0.513665062682276 0.642864324224729 0.343537039781257 0.642864324224729 0.642864324224729 0.642864324224729
Enoph1 ENSMUSG00000029326 0.450444934184774 0.675667401277161 0.924872384323464 0.924872384323464 0.345037391052887 0.675667401277161
Acads ENSMUSG00000029545 0.0449262652924809 0.114916742971844 0.926658283600152 0.926658283600152 0.0766111619812296 0.114916742971844
Sdsl ENSMUSG00000029596 0.514934023620344 0.514934023620344 0.00719286546902976 0.0215785964070893 0.17750354896016 0.26625532344024
Cyp3a25 ENSMUSG00000029630 0.701989711806957 0.701989711806957 0.334323804341914 0.501485706512871 0.112574347985553 0.337723043956658
Aass ENSMUSG00000029695 1 1 0.0753654386865988 0.226096316059796 0.710001140920767 1
Mogs ENSMUSG00000030036 0.642366752097095 0.642366752097095 0.452880492349546 0.642366752097095 0.399548817627028 0.642366752097095
Mtmr14 ENSMUSG00000030269 1 1 0.21549027811633 0.64647083434899 0.926003599371282 1
Cdipt ENSMUSG00000030682 0.573498913947369 0.573498913947369 0.505838378028518 0.573498913947369 0.295581119060361 0.573498913947369
Aldoa ENSMUSG00000030695 0.513665062682276 0.513665062682276 0.505838378028518 0.513665062682276 0.148115998140415 0.444347994421246
Lipt2 ENSMUSG00000030725 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041 0.398829756175299 0.926550375688041
Dgat2 ENSMUSG00000030747 0.09586901335616 0.28760704006848 0.641867098978198 0.641867098978198 0.45596561163947 0.641867098978198
Bcat2 ENSMUSG00000030826 0.346527959006435 0.456305241393103 0.298599969973533 0.456305241393103 0.456305241393103 0.456305241393103
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Agpat6 ENSMUSG00000031545 0.7802108304765 0.7802108304765 0.7802108304765 0.7802108304765 0.392985378348026 0.7802108304765
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ntpcr ENSMUSG00000031851 0.119631084167591 0.147458757705094 0.091411676944639 0.147458757705094 0.147458757705094 0.147458757705094
Acad8 ENSMUSG00000031969 0.254787123615605 0.764361370846816 0.780851835278817 1 1 1
Hmbs ENSMUSG00000032126 0.511742979522636 0.852065168704833 0.576973746230334 0.852065168704833 0.852065168704833 0.852065168704833
Nt5m ENSMUSG00000032615 0.168646652367079 0.384672302267076 0.346899083932133 0.384672302267076 0.384672302267076 0.384672302267076
Gmppa ENSMUSG00000033021 0.709375484777034 0.776919261684345 0.776919261684345 0.776919261684345 0.299349060054895 0.776919261684345
Pfkm ENSMUSG00000033065 0.146141353215796 0.37938057225181 0.925444427431699 0.925444427431699 0.252920381501207 0.37938057225181
Mif ENSMUSG00000033307 0.560950328333967 0.637793186752488 0.024062085667391 0.0721862570021729 0.637793186752488 0.637793186752488
Gstt2 ENSMUSG00000033318 0.400265374208515 0.400265374208515 0.400265374208515 0.400265374208515 0.17924968721805 0.400265374208515
Atp6v0b ENSMUSG00000033379 0.710001140920767 1 0.244170096021948 0.732510288065843 1 1
Fuk ENSMUSG00000033703 0.513026869856283 0.853694531487825 0.711034989117171 0.853694531487825 0.853694531487825 0.853694531487825
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Pomt2 ENSMUSG00000034126 0.852832278580641 0.852832278580641 0.578113371816017 0.852832278580641 0.640355507848752 0.852832278580641
Mtmr3 ENSMUSG00000034354 0.705968934865368 0.705968934865368 0.511742979522636 0.705968934865368 0.25141795904251 0.705968934865368
Dak ENSMUSG00000034371 0.178901132102685 0.505838378028518 0.505838378028518 0.505838378028518 0.395928178642446 0.505838378028518
Sirt6 ENSMUSG00000034748 0.297848640636702 0.577259514257969 0.455625354715449 0.577259514257969 0.577259514257969 0.577259514257969
Colgalt1 ENSMUSG00000034807 0.513026869856283 0.769540304784424 0.779238691542963 0.779238691542963 0.171503747555202 0.514511242665607
Tk2 ENSMUSG00000035824 0.144157978128026 0.216236967192039 0.505838378028518 0.505838378028518 0.117185073436597 0.216236967192039
Alg12 ENSMUSG00000035845 0.453570536021945 0.453570536021945 0.0701431284016184 0.210429385204855 0.398829756175299 0.453570536021945
Acaa1a ENSMUSG00000036138 0.146141353215796 0.438424059647387 0.577829325134931 0.643853282854191 0.643853282854191 0.643853282854191
Acaa2 ENSMUSG00000036880 0.0953125666339398 0.285937699901819 0.926333123228344 0.926333123228344 0.709375484777034 0.926333123228344
Pafah2 ENSMUSG00000037366 0.252545530864481 0.450143880930327 0.300095920620218 0.450143880930327 0.576973746230334 0.576973746230334
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Chpf2 ENSMUSG00000038181 0.57466664340579 0.861999965108685 0.57113445032749 0.861999965108685 1 1
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Mboat1 ENSMUSG00000038732 0.454600801949285 0.576112968612194 0.576112968612194 0.576112968612194 0.344663224299303 0.576112968612194
Pomt1 ENSMUSG00000039254 0.347639524025037 0.598244634262948 0.398829756175299 0.598244634262948 0.852832278580641 0.852832278580641
Ndst2 ENSMUSG00000039308 0.454600801949285 0.681901202923927 0.398829756175299 0.681901202923927 0.853801250889739 0.853801250889739
Atp6v0e2 ENSMUSG00000039347 0.214037080764326 0.321055621146488 0.636229315311352 0.636229315311352 0.178901132102685 0.321055621146488
Alg1 ENSMUSG00000039427 0.641867098978197 0.781170242226513 0.148772260628989 0.446316781886968 0.781170242226513 0.781170242226513
Dcxr ENSMUSG00000039450 0.511742979522636 1 1 1 0.926550375688041 1
Maob ENSMUSG00000040147 0.84992097596507 0.84992097596507 0.573498913947369 0.84992097596507 0.447265995733381 0.84992097596507
Gyltl1b ENSMUSG00000040434 0.0969812105731563 0.290943631719469 0.216214347033995 0.324321520550992 0.577259514257969 0.577259514257969
Pck2 ENSMUSG00000040618 0.780851835278818 0.780851835278818 0.243396309647536 0.365094464471304 0.18064054691103 0.365094464471304
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Hsd3b7 ENSMUSG00000042289 0.640355507848752 0.926550375688041 0.926550375688041 0.926550375688041 0.926333123228344 0.926550375688041
Setd1a ENSMUSG00000042308 0.642366752097095 0.642366752097095 0.342026805366747 0.642366752097095 0.45596561163947 0.642366752097095
Flad1 ENSMUSG00000042642 0.0443599545252852 0.133079863575856 0.45596561163947 0.639337105615664 0.639337105615664 0.639337105615664
Pgp ENSMUSG00000043445 0.577829325134931 0.711854160331342 0.640355507848752 0.711854160331342 0.711854160331342 0.711854160331342
Tst ENSMUSG00000044986 0.0116356061791785 0.0349068185375355 0.711650020253571 0.711650020253571 0.451840588205062 0.677760882307593
Idnk ENSMUSG00000050002 0.514934023620345 0.642864324224729 0.344663224299303 0.642864324224729 0.642864324224729 0.642864324224729
B3gnt2 ENSMUSG00000051650 0.25141795904251 0.447621891168214 0.348008842235184 0.447621891168214 0.447621891168214 0.447621891168214
Gapdh ENSMUSG00000057666 0.568427079091759 0.573205482926791 0.249528554620971 0.573205482926791 0.573205482926791 0.573205482926791
Fdps ENSMUSG00000059743 0.297848640636702 0.297848640636702 0.0947558980989551 0.284267694296865 0.255901190956604 0.297848640636702
Bckdha ENSMUSG00000060376 0.0566379395854603 0.169913818756381 0.576973746230334 0.576973746230334 0.213307944885796 0.319961917328694
Fhit ENSMUSG00000060579 0.398829756175299 0.577829325134931 0.577829325134931 0.577829325134931 0.346899083932133 0.577829325134931
Gstp1 ENSMUSG00000060803 0.388491809581663 0.388491809581663 0.279118898313835 0.388491809581663 0.174692232033629 0.388491809581663
Impdh2 ENSMUSG00000062867 0.341647690705446 0.592794569471191 0.853049270252403 0.853049270252403 0.395196379647461 0.592794569471191
Eno1 ENSMUSG00000063524 0.513026869856283 0.640355507848752 0.575536202757516 0.640355507848752 0.640355507848752 0.640355507848752
Ppcdc ENSMUSG00000063849 0.00719286546902974 0.0215785964070892 0.0325051220296005 0.0487576830444007 0.92392908126717 0.92392908126717
Mocs1 ENSMUSG00000064120 0.120545895661628 0.361637686984883 0.779238691542963 0.851732715229127 0.851732715229127 0.851732715229127
Ethe1 ENSMUSG00000064254 0.926550375688041 1 1 1 1 1
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
B3galt4 ENSMUSG00000067370 0.148444251782951 0.323778784497071 0.852065168704833 0.852065168704833 0.215852522998048 0.323778784497071
Gmppb ENSMUSG00000070284 0.447621891168214 0.573205482926791 0.573205482926791 0.573205482926791 0.5155648232968 0.573205482926791
Dgkd ENSMUSG00000070738 0.925444427431699 0.925444427431699 0.395928178642446 0.682414427663012 0.454942951775342 0.682414427663012
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095
Ganab ENSMUSG00000071650 0.576973746230334 0.853907737111068 0.853907737111068 0.853907737111068 0.576112968612194 0.853907737111068
Acot1 ENSMUSG00000072949 0.0751163767602349 0.112674565140352 0.576687400573867 0.576687400573867 0.0167871584516597 0.0503614753549791
Nme3 ENSMUSG00000073435 0.511742979522636 0.767614469283954 0.179249687218049 0.537749061654148 0.926550375688041 0.926550375688041
Dolk ENSMUSG00000075419 0.384672302267076 0.577008453400614 0.762100360299702 0.762100360299702 0.116265430850263 0.34879629255079
Dpm1 ENSMUSG00000078919 0.142830916318171 0.214246374477256 0.113190884633071 0.214246374477256 0.514934023620345 0.514934023620345
Cml5 ENSMUSG00000079494 0.214037080764326 0.321055621146489 0.853907737111068 0.853907737111068 0.0953125666339397 0.285937699901819
Ak9 ENSMUSG00000091415 0.255901190956604 0.767703572869812 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041
Vkorc1 ENSMUSG00000096145 0.642366752097095 0.642366752097095 0.17610058307789 0.52830174923367 0.640861491578951 0.642366752097095

Oxidative phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Atp6v1f ENSMUSG00000004285 0.573498913947369 0.573498913947369 0.451840588205062 0.573498913947369 0.511097249598474 0.573498913947369
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Atp6v0d1 ENSMUSG00000013160 0.509144723230069 0.562539849036184 0.562539849036184 0.562539849036184 0.343537039781257 0.562539849036184
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Atp6ap1 ENSMUSG00000019087 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.120850531362929 0.362551594088788
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Lhpp ENSMUSG00000030946 0.0753654386865988 0.226096316059796 1 1 0.779888212132595 1
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Atp6v0b ENSMUSG00000033379 0.710001140920767 1 0.244170096021948 0.732510288065843 1 1
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Atp6v0e2 ENSMUSG00000039347 0.214037080764326 0.321055621146488 0.636229315311352 0.636229315311352 0.178901132102685 0.321055621146488
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Parkinson disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Txn2 ENSMUSG00000005354 0.132079352483269 0.396238057449806 0.509144723230069 0.569937449249116 0.569937449249116 0.569937449249116
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Txn1 ENSMUSG00000028367 0.7802108304765 0.7802108304765 0.575824878403157 0.7802108304765 0.454600801949285 0.7802108304765
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Maob ENSMUSG00000040147 0.84992097596507 0.84992097596507 0.573498913947369 0.84992097596507 0.447265995733381 0.84992097596507
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Htra2 ENSMUSG00000068329 0.254414773803597 0.586125987157192 0.390750658104795 0.586125987157192 0.706831781264721 0.706831781264721
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Huntington disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Cacna1b ENSMUSG00000004113 0.0321889748775514 0.0965669246326542 0.852065168704833 0.852065168704833 0.395928178642446 0.593892267963669
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ap2s1 ENSMUSG00000008036 0.281535759592779 0.33116978622016 0.0869438727002335 0.2608316181007 0.33116978622016 0.33116978622016
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Polr2c ENSMUSG00000031783 0.638824656785692 0.638824656785692 0.452880492349546 0.638824656785692 0.29252580908486 0.638824656785692
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Polr2f ENSMUSG00000033020 0.637274134311157 0.637274134311157 0.299349060054896 0.637274134311157 0.575536202757516 0.637274134311157
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Polr2l ENSMUSG00000038489 0.772410589885492 0.772410589885492 0.0701431284016185 0.210429385204856 0.50716883916608 0.760753258749121
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Amyotrophic lateral sclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Tomm40 ENSMUSG00000002984 0.148115998140416 0.444347994421247 0.775217051297351 0.775217051297351 0.503822527122732 0.755733790684098
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Tomm40l ENSMUSG00000005674 0.138156294413154 0.299835030563952 0.199890020375968 0.299835030563952 0.509144723230069 0.509144723230069
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Nup85 ENSMUSG00000020739 0.454600801949285 0.683438032073173 0.455625354715448 0.683438032073173 0.852832278580641 0.852832278580641
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Bad ENSMUSG00000024959 0.704220158648919 0.704220158648919 0.637274134311157 0.704220158648919 0.508488713161374 0.704220158648919
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Nup210l ENSMUSG00000027939 0.5155648232968 0.5155648232968 0.297848640636702 0.446772960955053 0.0331400397096515 0.0994201191289544
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Gabarapl2 ENSMUSG00000031950 0.852940894477647 0.853480389728993 0.451840588205062 0.853480389728993 0.853480389728993 0.853480389728993
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ccs ENSMUSG00000034108 0.211844580334808 0.323235417174495 0.21549027811633 0.323235417174495 0.388491809581663 0.388491809581663
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Nup188 ENSMUSG00000052533 0.214037080764326 0.252545530864481 0.179249687218049 0.252545530864481 0.252545530864481 0.252545530864481
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Actg1 ENSMUSG00000062825 0.214037080764326 0.321055621146488 0.327972855903273 0.327972855903273 0.211110344399808 0.321055621146488
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Map2k1 ENSMUSG00000004936 0.92622377157404 0.92622377157404 0.5155648232968 0.7733472349452 0.514934023620345 0.7733472349452
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Aph1a ENSMUSG00000015750 0.451840588205062 0.764697207151727 0.78148726569172 0.78148726569172 0.509798138101151 0.764697207151727
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Bad ENSMUSG00000024959 0.704220158648919 0.704220158648919 0.637274134311157 0.704220158648919 0.508488713161374 0.704220158648919
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Cdk5 ENSMUSG00000028969 0.399548817627028 0.455625354715449 0.0733738589968007 0.220121576990402 0.455625354715449 0.455625354715449
Dvl1 ENSMUSG00000029071 0.347639524025037 0.576973746230334 0.576973746230334 0.576973746230334 0.45596561163947 0.576973746230334
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Map2k2 ENSMUSG00000035027 0.381566259882379 0.572349389823568 0.0588232673880149 0.176469802164045 0.709375484777034 0.709375484777034
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Psenen ENSMUSG00000036835 0.21549027811633 0.51755608657933 0.575536202757516 0.575536202757516 0.345037391052887 0.51755608657933
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Frat2 ENSMUSG00000047604 0.514300775319626 0.771451162979439 1 1 0.454942951775341 0.771451162979439
Aph1c ENSMUSG00000053040 0.453570536021945 0.782117202022501 0.573205482926791 0.782117202022501 0.782117202022501 0.782117202022501
Gapdh ENSMUSG00000057666 0.568427079091759 0.573205482926791 0.249528554620971 0.573205482926791 0.573205482926791 0.573205482926791
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Mapk1 ENSMUSG00000063358 0.711650020253571 0.853049270252403 0.853049270252403 0.853049270252403 0.578113371816017 0.853049270252403
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Tomm40 ENSMUSG00000002984 0.148115998140416 0.444347994421247 0.775217051297351 0.775217051297351 0.503822527122732 0.755733790684098
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Cacna1b ENSMUSG00000004113 0.0321889748775514 0.0965669246326542 0.852065168704833 0.852065168704833 0.395928178642446 0.593892267963669
Map2k1 ENSMUSG00000004936 0.92622377157404 0.92622377157404 0.5155648232968 0.7733472349452 0.514934023620345 0.7733472349452
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Tomm40l ENSMUSG00000005674 0.138156294413154 0.299835030563952 0.199890020375968 0.299835030563952 0.509144723230069 0.509144723230069
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Bad ENSMUSG00000024959 0.704220158648919 0.704220158648919 0.637274134311157 0.704220158648919 0.508488713161374 0.704220158648919
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Cdk5 ENSMUSG00000028969 0.399548817627028 0.455625354715449 0.0733738589968007 0.220121576990402 0.455625354715449 0.455625354715449
Dvl1 ENSMUSG00000029071 0.347639524025037 0.576973746230334 0.576973746230334 0.576973746230334 0.45596561163947 0.576973746230334
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Gabarapl2 ENSMUSG00000031950 0.852940894477647 0.853480389728993 0.451840588205062 0.853480389728993 0.853480389728993 0.853480389728993
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ccs ENSMUSG00000034108 0.211844580334808 0.323235417174495 0.21549027811633 0.323235417174495 0.388491809581663 0.388491809581663
Map2k2 ENSMUSG00000035027 0.381566259882379 0.572349389823568 0.0588232673880149 0.176469802164045 0.709375484777034 0.709375484777034
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Frat2 ENSMUSG00000047604 0.514300775319626 0.771451162979439 1 1 0.454942951775341 0.771451162979439
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Mapk1 ENSMUSG00000063358 0.711650020253571 0.853049270252403 0.853049270252403 0.853049270252403 0.578113371816017 0.853049270252403
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Htra2 ENSMUSG00000068329 0.254414773803597 0.586125987157192 0.390750658104795 0.586125987157192 0.706831781264721 0.706831781264721
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Prion disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Tubb5 ENSMUSG00000001525 0.211844580334808 0.323235417174495 0.329176790045262 0.329176790045262 0.21549027811633 0.323235417174495
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Cacna1b ENSMUSG00000004113 0.0321889748775514 0.0965669246326542 0.852065168704833 0.852065168704833 0.395928178642446 0.593892267963669
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Bad ENSMUSG00000024959 0.704220158648919 0.704220158648919 0.637274134311157 0.704220158648919 0.508488713161374 0.704220158648919
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Mapk1 ENSMUSG00000063358 0.711650020253571 0.853049270252403 0.853049270252403 0.853049270252403 0.578113371816017 0.853049270252403
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Thermogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Coa3 ENSMUSG00000017188 0.0443599545252853 0.133079863575856 0.345410946355104 0.345410946355104 0.178901132102685 0.268351698154027
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Slc25a29 ENSMUSG00000021265 0.341647690705446 0.925669613555092 0.925669613555092 0.925669613555092 0.7802108304765 0.925669613555092
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Coa5 ENSMUSG00000026112 0.92622377157404 0.92622377157404 0.118409250205154 0.355227750615461 0.711650020253571 0.92622377157404
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Slc25a20 ENSMUSG00000032602 0.146141353215796 0.438424059647387 0.578396848531894 0.578396848531894 0.514300775319626 0.578396848531894
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Sirt6 ENSMUSG00000034748 0.297848640636702 0.577259514257969 0.455625354715449 0.577259514257969 0.577259514257969 0.577259514257969
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Actg1 ENSMUSG00000062825 0.214037080764326 0.321055621146488 0.327972855903273 0.327972855903273 0.211110344399808 0.321055621146488
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Prkag1 ENSMUSG00000067713 0.342026805366747 0.51304020805012 1 1 0.254414773803597 0.51304020805012
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Lysosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Psap ENSMUSG00000004207 0.178901132102684 0.268351698154027 0.638824656785692 0.638824656785692 0.11595859961889 0.268351698154027
Mcoln1 ENSMUSG00000004567 0.255901190956604 0.443371678590541 0.780851835278817 0.780851835278817 0.295581119060361 0.443371678590541
Ap1b1 ENSMUSG00000009090 0.213307944885796 0.319961917328694 0.499716455239609 0.499716455239609 0.0579478375430677 0.173843512629203
Atp6v0d1 ENSMUSG00000013160 0.509144723230069 0.562539849036184 0.562539849036184 0.562539849036184 0.343537039781257 0.562539849036184
Ctsa ENSMUSG00000017760 0.77169240001909 0.926333123228344 0.926333123228344 0.926333123228344 0.6978446011211 0.926333123228344
Atp6ap1 ENSMUSG00000019087 0.853372965654504 0.853372965654504 0.711854160331342 0.853372965654504 0.120850531362929 0.362551594088788
Laptm4a ENSMUSG00000020585 0.711034989117171 0.711034989117171 0.577829325134931 0.711034989117171 0.216214347033995 0.648643041101984
Npc2 ENSMUSG00000021242 0.254787123615605 0.449023590082343 0.642366752097095 0.642366752097095 0.299349060054895 0.449023590082343
Gm21685 ENSMUSG00000022066 0.511742979522636 0.767614469283954 0.178901132102685 0.536703396308054 0.7802108304765 0.7802108304765
Laptm4b ENSMUSG00000022257 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.300095920620218 0.853801250889739
Fuca1 ENSMUSG00000028673 0.643359829732651 0.643359829732651 0.397384062266614 0.643359829732651 0.514934023620345 0.643359829732651
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
Cln3 ENSMUSG00000030720 1 1 0.851061028660105 1 0.213307944885796 0.639923834657388
Gga2 ENSMUSG00000030872 0.709375484777034 0.709375484777034 0.0761127945805736 0.228338383741721 0.254414773803597 0.381622160705395
Pla2g15 ENSMUSG00000031903 0.513665062682276 0.514934023620345 0.452880492349546 0.514934023620345 0.514934023620345 0.514934023620345
Atp6v0b ENSMUSG00000033379 0.710001140920767 1 0.244170096021948 0.732510288065843 1 1
Gnptg ENSMUSG00000035521 0.29252580908486 0.640355507848752 0.573791743469336 0.640355507848752 0.640355507848752 0.640355507848752
Ap3b2 ENSMUSG00000062444 0.446194239410717 0.573205482926791 0.0947558980989551 0.284267694296865 0.573205482926791 0.573205482926791
Ctsf ENSMUSG00000083282 0.445116333668945 0.670898993600072 0.852504981253341 0.852504981253341 0.447265995733381 0.670898993600072

Biosynthesis of cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Coq6 ENSMUSG00000021235 0.782117202022501 0.782117202022501 0.297095062262363 0.767614469283954 0.511742979522636 0.767614469283954
Naprt1 ENSMUSG00000022574 0.45596561163947 0.683948417459205 0.148772260628989 0.446316781886968 0.853907737111068 0.853907737111068
Alad ENSMUSG00000028393 0.246861959455465 0.370292939183197 0.57113445032749 0.57113445032749 0.118409250205154 0.355227750615461
Ctps ENSMUSG00000028633 0.641867098978198 0.641867098978198 0.17610058307789 0.52830174923367 0.398829756175299 0.598244634262948
Akr1a1 ENSMUSG00000028692 0.576973746230334 0.576973746230334 0.344663224299303 0.51755608657933 0.345037391052887 0.51755608657933
Cmpk1 ENSMUSG00000028719 0.00768144932639892 0.0230443479791968 0.711650020253571 0.711650020253571 0.213307944885796 0.319961917328694
Ak2 ENSMUSG00000028792 0.576973746230334 1 1 1 0.781170242226513 1
Nadk ENSMUSG00000029063 0.453225835454266 0.573791743469336 0.509144723230069 0.573791743469336 0.573791743469336 0.573791743469336
Lias ENSMUSG00000029199 0.513665062682276 0.642864324224729 0.343537039781257 0.642864324224729 0.642864324224729 0.642864324224729
Lipt2 ENSMUSG00000030725 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041 0.398829756175299 0.926550375688041
Bcat2 ENSMUSG00000030826 0.346527959006435 0.456305241393103 0.298599969973533 0.456305241393103 0.456305241393103 0.456305241393103
Hmbs ENSMUSG00000032126 0.511742979522636 0.852065168704833 0.576973746230334 0.852065168704833 0.852065168704833 0.852065168704833
Gmppa ENSMUSG00000033021 0.709375484777034 0.776919261684345 0.776919261684345 0.776919261684345 0.299349060054895 0.776919261684345
Flad1 ENSMUSG00000042642 0.0443599545252852 0.133079863575856 0.45596561163947 0.639337105615664 0.639337105615664 0.639337105615664
Ppcdc ENSMUSG00000063849 0.00719286546902974 0.0215785964070892 0.0325051220296005 0.0487576830444007 0.92392908126717 0.92392908126717
Mocs1 ENSMUSG00000064120 0.120545895661628 0.361637686984883 0.779238691542963 0.851732715229127 0.851732715229127 0.851732715229127
Gmppb ENSMUSG00000070284 0.447621891168214 0.573205482926791 0.573205482926791 0.573205482926791 0.5155648232968 0.573205482926791
Nme3 ENSMUSG00000073435 0.511742979522636 0.767614469283954 0.179249687218049 0.537749061654148 0.926550375688041 0.926550375688041
Ak9 ENSMUSG00000091415 0.255901190956604 0.767703572869812 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041
Vkorc1 ENSMUSG00000096145 0.642366752097095 0.642366752097095 0.17610058307789 0.52830174923367 0.640861491578951 0.642366752097095

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Mpc2 ENSMUSG00000026568 0.5155648232968 0.5155648232968 0.249907451332337 0.374861176998506 0.216214347033995 0.374861176998506
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Ppp2r4 ENSMUSG00000039515 0.297848640636703 0.446772960955054 0.852065168704833 0.852065168704833 0.058823267388015 0.176469802164045
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Gapdh ENSMUSG00000057666 0.568427079091759 0.573205482926791 0.249528554620971 0.573205482926791 0.573205482926791 0.573205482926791
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Non-alcoholic fatty liver disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Bax ENSMUSG00000003873 0.706831781264721 0.706831781264721 0.578396848531894 0.706831781264721 0.576112968612194 0.706831781264721
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Cox8b ENSMUSG00000025488 0.506837221875456 0.63856761373451 0.63856761373451 0.63856761373451 0.506837221875456 0.63856761373451
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Cox6a1 ENSMUSG00000041697 0.120545895661628 0.361637686984883 0.849805525376199 0.924286968561133 0.924286968561133 0.924286968561133
Prkag1 ENSMUSG00000067713 0.342026805366747 0.51304020805012 1 1 0.254414773803597 0.51304020805012
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Mitochondrial translation elongation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl2 ENSMUSG00000002767 0.178901132102685 0.536703396308054 0.575536202757516 0.575536202757516 0.395196379647461 0.575536202757516
Mrpl4 ENSMUSG00000003299 0.287873078401389 0.78180291566155 0.78180291566155 0.78180291566155 0.637274134311157 0.78180291566155
Mrps25 ENSMUSG00000014551 0.780851835278818 0.780851835278818 0.0947558980989551 0.284267694296865 0.643359829732651 0.780851835278818
Mrpl45 ENSMUSG00000018882 0.346899083932133 0.520348625898199 0.298599969973533 0.520348625898199 0.926441990075769 0.926441990075769
Mrps24 ENSMUSG00000020477 0.399548817627028 0.599323226440542 0.213307944885796 0.599323226440542 0.642366752097095 0.642366752097095
Eral1 ENSMUSG00000020832 0.514300775319626 0.577259514257969 0.577259514257969 0.577259514257969 0.297095062262363 0.577259514257969
Mrpl36 ENSMUSG00000021607 0.852504981253341 0.852504981253341 0.348008842235184 0.852504981253341 0.711034989117171 0.852504981253341
Mrp63 ENSMUSG00000021967 0.300095920620218 0.520348625898199 0.346899083932133 0.520348625898199 0.853801250889739 0.853801250889739
Mrpl14 ENSMUSG00000023939 0.249907451332337 0.451840588205062 0.398108175780842 0.451840588205062 0.451840588205062 0.451840588205062
Mrpl28 ENSMUSG00000024181 0.242231702094921 0.388491809581663 0.319786844594194 0.388491809581663 0.388491809581663 0.388491809581663
Mrpl16 ENSMUSG00000024683 0.253294730253595 0.379942095380392 0.0432318933800775 0.129695680140233 0.447621891168214 0.447621891168214
Mrpl44 ENSMUSG00000026248 0.638824656785692 0.778911768167544 0.397384062266614 0.778911768167544 0.778911768167544 0.778911768167544
Mrpl53 ENSMUSG00000030037 0.706616781330066 0.706616781330066 0.638310022345193 0.706616781330066 0.513665062682276 0.706616781330066
Mrpl17 ENSMUSG00000030879 0.638310022345193 0.926658283600152 0.926658283600152 0.926658283600152 0.777922216623952 0.926658283600152
Mrpl54 ENSMUSG00000034932 0.255530331334266 0.599323226440542 0.709375484777034 0.709375484777034 0.399548817627028 0.599323226440542
Mrpl41 ENSMUSG00000036850 0.17924968721805 0.53774906165415 0.780851835278818 0.780851835278818 0.711034989117171 0.780851835278818
Mrpl55 ENSMUSG00000036860 0.853480389728993 0.853480389728993 0.253294730253594 0.759884190760783 0.514300775319626 0.771451162979439
Mrps26 ENSMUSG00000037740 0.252920381501207 0.75876114450362 0.636229315311352 0.7802108304765 0.7802108304765 0.7802108304765
Mrps34 ENSMUSG00000038880 0.342026805366747 0.852175490580835 0.706616781330066 0.852175490580835 0.852175490580835 0.852175490580835
Mrps27 ENSMUSG00000041632 0.096425230538547 0.289275691615641 0.254787123615605 0.343537039781257 0.343537039781257 0.343537039781257
Mrps12 ENSMUSG00000045948 0.567513221841557 0.567513221841557 0.0432318933800775 0.129695680140232 0.446194239410717 0.567513221841557
Mrps7 ENSMUSG00000046756 0.578113371816017 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Mrps36 ENSMUSG00000061474 0.456305241393103 0.456305241393103 0.180293335960318 0.270440003940477 0.0375110574079901 0.11253317222397

Metabolism of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo7 ENSMUSG00000001786 0.299349060054895 0.853372965654504 0.853372965654504 0.853372965654504 0.852940894477647 0.853372965654504
Ltbp1 ENSMUSG00000001870 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344 0.514934023620345 0.926333123228344
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Mrpl2 ENSMUSG00000002767 0.178901132102685 0.536703396308054 0.575536202757516 0.575536202757516 0.395196379647461 0.575536202757516
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Btbd6 ENSMUSG00000002803 0.0761127945805735 0.22833838374172 0.774871910813158 0.774871910813158 0.255530331334266 0.383295497001398
Eif2b5 ENSMUSG00000003235 0.0953125666339397 0.174398146275395 0.766080166042519 0.766080166042519 0.116265430850263 0.174398146275395
Mrpl4 ENSMUSG00000003299 0.287873078401389 0.78180291566155 0.78180291566155 0.78180291566155 0.637274134311157 0.78180291566155
Paf1 ENSMUSG00000003437 0.926441990075769 0.926441990075769 0.0969812105731562 0.290943631719469 0.576973746230334 0.865460619345501
Cul3 ENSMUSG00000004364 0.0321889748775514 0.0620489870967841 0.0413659913978561 0.0620489870967841 0.0753654386865988 0.0753654386865988
Pex5 ENSMUSG00000005069 0.924872384323463 1 1 1 0.77858338846904 1
Fbxo11 ENSMUSG00000005371 0.0113901882503033 0.0341705647509098 0.926333123228344 0.926333123228344 0.577259514257969 0.865889271386954
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Rps9 ENSMUSG00000006333 0.347639524025037 0.926550375688041 0.643853282854191 0.926550375688041 0.926550375688041 0.926550375688041
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Pigl ENSMUSG00000014245 0.449743164679353 0.710208797518812 0.710208797518812 0.710208797518812 0.63856761373451 0.710208797518812
Mrps25 ENSMUSG00000014551 0.780851835278818 0.780851835278818 0.0947558980989551 0.284267694296865 0.643359829732651 0.780851835278818
Fbxw5 ENSMUSG00000015095 0.119631084167591 0.358893252502774 0.57466664340579 0.705968934865368 0.705968934865368 0.705968934865368
Actr8 ENSMUSG00000015971 0.853372965654504 1 1 1 0.45596561163947 1
Ube2a ENSMUSG00000016308 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Eif3d ENSMUSG00000016554 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.119631084167592 0.317766870502212
Ctsa ENSMUSG00000017760 0.77169240001909 0.926333123228344 0.926333123228344 0.926333123228344 0.6978446011211 0.926333123228344
Hist1h2bc ENSMUSG00000018102 0.453225835454266 0.780851835278817 0.780851835278817 0.780851835278817 0.643359829732651 0.780851835278817
Pcgf2 ENSMUSG00000018537 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053 1 1
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Mrpl45 ENSMUSG00000018882 0.346899083932133 0.520348625898199 0.298599969973533 0.520348625898199 0.926441990075769 0.926441990075769
Arrb1 ENSMUSG00000018909 0.295581119060361 0.443371678590541 0.640861491578951 0.640861491578951 0.146800541856249 0.440401625568746
Fkbp8 ENSMUSG00000019428 0.0716332429957515 0.214899728987254 0.501782052576058 0.501782052576058 0.447621891168214 0.501782052576058
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Fbxw11 ENSMUSG00000020271 0.638824656785692 0.958236985178538 1 1 0.513665062682276 0.958236985178538
Mgat1 ENSMUSG00000020346 0.0240620856673909 0.0721862570021728 0.711854160331342 1 1 1
Mrps24 ENSMUSG00000020477 0.399548817627028 0.599323226440542 0.213307944885796 0.599323226440542 0.642366752097095 0.642366752097095
Apob ENSMUSG00000020609 0.853372965654504 0.853372965654504 0.0577292451600846 0.173187735480254 0.577829325134931 0.853372965654504
Nup85 ENSMUSG00000020739 0.454600801949285 0.683438032073173 0.455625354715448 0.683438032073173 0.852832278580641 0.852832278580641
Srp68 ENSMUSG00000020780 0.511742979522636 0.767614469283954 0.778911768167544 0.778911768167544 0.146800541856249 0.440401625568746
Eral1 ENSMUSG00000020832 0.514300775319626 0.577259514257969 0.577259514257969 0.577259514257969 0.297095062262363 0.577259514257969
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Dcaf4 ENSMUSG00000021222 0.0113089139751576 0.0339267419254727 0.255901190956604 0.348008842235184 0.348008842235184 0.348008842235184
Exoc2 ENSMUSG00000021357 0.513026869856283 0.513026869856283 0.348008842235184 0.513026869856283 0.299349060054895 0.513026869856283
Mrpl36 ENSMUSG00000021607 0.852504981253341 0.852504981253341 0.348008842235184 0.852504981253341 0.711034989117171 0.852504981253341
Mrp63 ENSMUSG00000021967 0.300095920620218 0.520348625898199 0.346899083932133 0.520348625898199 0.853801250889739 0.853801250889739
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Tab1 ENSMUSG00000022414 0.117185073436597 0.351555220309791 0.711650020253571 0.711650020253571 0.456305241393103 0.684457862089655
Josd1 ENSMUSG00000022426 0.299349060054895 0.85117361048289 0.85117361048289 0.85117361048289 0.640861491578951 0.85117361048289
Hdac7 ENSMUSG00000022475 0.453225835454266 0.679838753181399 0.708534948098331 0.708534948098331 0.398829756175299 0.679838753181399
Gpaa1 ENSMUSG00000022561 0.146141353215796 0.438424059647387 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Fstl1 ENSMUSG00000022816 0.343537039781257 0.683948417459205 1 1 0.45596561163947 0.683948417459205
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Mrpl14 ENSMUSG00000023939 0.249907451332337 0.451840588205062 0.398108175780842 0.451840588205062 0.451840588205062 0.451840588205062
Spsb3 ENSMUSG00000024160 0.0441715176243982 0.132514552873195 0.925444427431699 0.925444427431699 0.119631084167592 0.179446626251387
Mrpl28 ENSMUSG00000024181 0.242231702094921 0.388491809581663 0.319786844594194 0.388491809581663 0.388491809581663 0.388491809581663
Adamts10 ENSMUSG00000024299 0.398108175780842 0.770497594023414 0.853049270252403 0.853049270252403 0.513665062682276 0.770497594023414
Mrpl16 ENSMUSG00000024683 0.253294730253595 0.379942095380392 0.0432318933800775 0.129695680140233 0.447621891168214 0.447621891168214
Ddb1 ENSMUSG00000024740 0.509144723230069 0.763717084845103 0.92622377157404 0.92622377157404 0.295581119060361 0.763717084845103
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Fbxl15 ENSMUSG00000025226 0.57466664340579 0.853801250889739 0.0936419271039908 0.280925781311972 0.853801250889739 0.853801250889739
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Rplp2 ENSMUSG00000025508 0.146800541856249 0.440401625568746 0.297848640636702 0.446772960955053 0.709375484777034 0.709375484777034
Sumf2 ENSMUSG00000025538 0.21549027811633 0.400265374208515 0.297095062262362 0.400265374208515 0.400265374208515 0.400265374208515
Rab40c ENSMUSG00000025730 0.509798138101151 0.509798138101151 0.180293335960318 0.509798138101151 0.509798138101151 0.509798138101151
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Mrpl44 ENSMUSG00000026248 0.638824656785692 0.778911768167544 0.397384062266614 0.778911768167544 0.778911768167544 0.778911768167544
Asb1 ENSMUSG00000026311 0.708534948098331 0.708534948098331 0.0743693776059065 0.223108132817719 0.294820734456232 0.442231101684348
Rgs7 ENSMUSG00000026527 0.177853449259986 0.381622160705395 0.254414773803597 0.381622160705395 1 1
Wdr5 ENSMUSG00000026917 0.249907451332337 0.681901202923927 0.454600801949285 0.681901202923927 0.708534948098331 0.708534948098331
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Commd9 ENSMUSG00000027163 0.00143725611474427 0.0043117683442328 0.711650020253571 0.711650020253571 0.513665062682276 0.711650020253571
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dcun1d1 ENSMUSG00000027708 0.0969812105731562 0.290943631719469 0.780851835278818 0.780851835278818 0.638310022345193 0.780851835278818
Txn1 ENSMUSG00000028367 0.7802108304765 0.7802108304765 0.575824878403157 0.7802108304765 0.454600801949285 0.7802108304765
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Gne ENSMUSG00000028479 0.777255087907932 0.777255087907932 0.569937449249116 0.777255087907932 0.0441715176243983 0.132514552873195
Dph2 ENSMUSG00000028540 0.78180291566155 0.853049270252403 0.781170242226513 0.853049270252403 0.853049270252403 0.853049270252403
Fuca1 ENSMUSG00000028673 0.643359829732651 0.643359829732651 0.397384062266614 0.643359829732651 0.514934023620345 0.643359829732651
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Gnb2 ENSMUSG00000029713 0.024062085667391 0.0721862570021729 0.455625354715449 0.683438032073173 0.779238691542963 0.779238691542963
Cct7 ENSMUSG00000030007 0.926658283600152 0.926658283600152 0.146800541856249 0.440401625568747 0.643853282854191 0.926658283600152
Mrpl53 ENSMUSG00000030037 0.706616781330066 0.706616781330066 0.638310022345193 0.706616781330066 0.513665062682276 0.706616781330066
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Rpl28 ENSMUSG00000030432 0.398108175780842 0.78148726569172 0.57466664340579 0.78148726569172 0.78148726569172 0.78148726569172
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Mrpl17 ENSMUSG00000030879 0.638310022345193 0.926658283600152 0.926658283600152 0.926658283600152 0.777922216623952 0.926658283600152
Eif3f ENSMUSG00000031029 0.0947558980989551 0.284267694296865 0.9255572759333 0.9255572759333 0.395196379647461 0.592794569471191
Ccdc22 ENSMUSG00000031143 0.345037391052887 0.7802108304765 0.7802108304765 0.7802108304765 0.778911768167544 0.7802108304765
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Brcc3 ENSMUSG00000031201 0.17750354896016 0.26625532344024 1 1 0.144820068500793 0.26625532344024
Usp10 ENSMUSG00000031826 0.179945789077372 0.539837367232116 0.711240436189781 0.712057867818062 0.712057867818062 0.712057867818062
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Gnb5 ENSMUSG00000032192 0.179945789077372 0.539837367232115 0.712057867818062 0.926658283600152 0.926658283600152 0.926658283600152
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Eif3l ENSMUSG00000033047 0.7048795965722 0.711034989117171 0.711034989117171 0.711034989117171 0.236337185850513 0.70901155755154
Qsox1 ENSMUSG00000033684 0.57113445032749 0.853694531487825 0.853694531487825 0.853694531487825 0.0733738589968007 0.220121576990402
Fuk ENSMUSG00000033703 0.513026869856283 0.853694531487825 0.711034989117171 0.853694531487825 0.853694531487825 0.853694531487825
Vhl ENSMUSG00000033933 0.299349060054895 0.898047180164686 1 1 0.708323672944427 1
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Rab24 ENSMUSG00000034789 0.119631084167591 0.179446626251387 0.213307944885796 0.213307944885796 0.0535981760208403 0.160794528062521
Mrpl54 ENSMUSG00000034932 0.255530331334266 0.599323226440542 0.709375484777034 0.709375484777034 0.399548817627028 0.599323226440542
Eef2 ENSMUSG00000034994 0.249907451332337 0.374861176998506 0.77858338846904 0.77858338846904 0.0741204440774083 0.222361332232225
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Eva1a ENSMUSG00000035104 0.297848640636702 0.78180291566155 0.78180291566155 0.78180291566155 0.642864324224729 0.78180291566155
Fam175a ENSMUSG00000035234 0.509144723230069 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Alg12 ENSMUSG00000035845 0.453570536021945 0.453570536021945 0.0701431284016184 0.210429385204855 0.398829756175299 0.453570536021945
Mrpl41 ENSMUSG00000036850 0.17924968721805 0.53774906165415 0.780851835278818 0.780851835278818 0.711034989117171 0.780851835278818
Mrpl55 ENSMUSG00000036860 0.853480389728993 0.853480389728993 0.253294730253594 0.759884190760783 0.514300775319626 0.771451162979439
Kin ENSMUSG00000037262 0.453570536021945 0.7802108304765 0.703333998861023 0.7802108304765 0.7802108304765 0.7802108304765
Ctbp1 ENSMUSG00000037373 0.148115998140415 0.377126938563765 0.577259514257969 0.577259514257969 0.25141795904251 0.377126938563765
Mcrs1 ENSMUSG00000037570 0.162867964743396 0.488603894230187 0.711650020253571 0.711650020253571 0.706831781264721 0.711650020253571
Mrps26 ENSMUSG00000037740 0.252920381501207 0.75876114450362 0.636229315311352 0.7802108304765 0.7802108304765 0.7802108304765
Usp5 ENSMUSG00000038429 0.249907451332337 0.438889219142351 0.438889219142351 0.438889219142351 0.334715083204387 0.438889219142351
Trmt112 ENSMUSG00000038812 0.926496242814507 0.926496242814507 0.120241108790035 0.222666377674426 0.148444251782951 0.222666377674426
Mrps34 ENSMUSG00000038880 0.342026805366747 0.852175490580835 0.706616781330066 0.852175490580835 0.852175490580835 0.852175490580835
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Alg1 ENSMUSG00000039427 0.641867098978197 0.781170242226513 0.148772260628989 0.446316781886968 0.781170242226513 0.781170242226513
Mettl20 ENSMUSG00000039958 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041 0.926550375688041 0.926550375688041
Gyltl1b ENSMUSG00000040434 0.0969812105731563 0.290943631719469 0.216214347033995 0.324321520550992 0.577259514257969 0.577259514257969
Rabggta ENSMUSG00000040472 0.117185073436597 0.31000343112373 0.643359829732651 0.643359829732651 0.206668954082487 0.31000343112373
Eif4h ENSMUSG00000040731 0.119631084167592 0.221188136557642 0.778911768167544 0.778911768167544 0.147458757705094 0.221188136557642
Fbxw4 ENSMUSG00000040913 0.297848640636702 0.446772960955053 0.254414773803597 0.446772960955053 0.709375484777034 0.709375484777034
Fbxo2 ENSMUSG00000041556 0.0766111619812296 0.229833485943689 0.703556284613037 0.703556284613037 0.577829325134931 0.703556284613037
Mrps27 ENSMUSG00000041632 0.096425230538547 0.289275691615641 0.254787123615605 0.343537039781257 0.343537039781257 0.343537039781257
Commd10 ENSMUSG00000042705 0.252545530864481 0.757636592593443 1 1 0.513026869856283 0.769540304784424
Taf10 ENSMUSG00000043866 0.0113089139751576 0.0339267419254727 0.848280005680805 0.848280005680805 0.702439833942814 0.848280005680805
Rps2 ENSMUSG00000044533 0.140165358447409 0.220200812784373 0.146800541856249 0.220200812784373 0.779238691542963 0.779238691542963
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Mrps12 ENSMUSG00000045948 0.567513221841557 0.567513221841557 0.0432318933800775 0.129695680140232 0.446194239410717 0.567513221841557
Mrps7 ENSMUSG00000046756 0.578113371816017 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Tada3 ENSMUSG00000048930 0.572616808177226 0.925669613555092 0.782117202022501 0.925669613555092 0.925669613555092 0.925669613555092
B3gnt2 ENSMUSG00000051650 0.25141795904251 0.447621891168214 0.348008842235184 0.447621891168214 0.447621891168214 0.447621891168214
Nup188 ENSMUSG00000052533 0.214037080764326 0.252545530864481 0.179249687218049 0.252545530864481 0.252545530864481 0.252545530864481
Sae1 ENSMUSG00000052833 0.392985378348026 0.589478067522039 0.638824656785692 0.638824656785692 0.338592117141989 0.589478067522039
Fbxo6 ENSMUSG00000055401 0.254414773803597 0.711034989117171 0.643359829732651 0.711034989117171 0.711034989117171 0.711034989117171
Klhl25 ENSMUSG00000055652 0.254414773803597 0.683438032073173 0.92622377157404 0.92622377157404 0.455625354715449 0.683438032073173
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Commd7 ENSMUSG00000056941 1 1 0.398108175780842 1 0.853372965654504 1
St6galnac2 ENSMUSG00000057286 0.578113371816017 0.853694531487825 0.853694531487825 0.853694531487825 0.711854160331342 0.853694531487825
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
H2afj ENSMUSG00000060032 0.0953125666339397 0.285937699901819 0.250285839267991 0.375428758901986 0.576112968612194 0.576112968612194
Dhps ENSMUSG00000060038 0.144157978128026 0.266780173889979 0.177853449259986 0.266780173889979 0.643359829732651 0.643359829732651
Nr1h2 ENSMUSG00000060601 0.346527959006435 0.519791938509652 0.252545530864481 0.519791938509652 0.573498913947369 0.573498913947369
Hist1h4i ENSMUSG00000060639 0.29252580908486 0.776919261684345 0.776919261684345 0.776919261684345 0.711034989117171 0.776919261684345
Hist1h4h ENSMUSG00000060981 0.78148726569172 1 1 1 0.5155648232968 1
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Mrps36 ENSMUSG00000061474 0.456305241393103 0.456305241393103 0.180293335960318 0.270440003940477 0.0375110574079901 0.11253317222397
Gspt1 ENSMUSG00000062203 0.0325051220296005 0.0975153660888015 0.926658283600152 1 1 1
Suds3 ENSMUSG00000066900 0.25141795904251 0.377126938563765 0.772767153280156 0.772767153280156 0.178901132102685 0.377126938563765
Srp54a ENSMUSG00000073079 0.0562022152993845 0.168606645898153 0.577829325134931 0.866743987702397 0.92622377157404 0.92622377157404
Klhl21 ENSMUSG00000073700 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171 0.455625354715449 0.711034989117171
Hist1h2bb ENSMUSG00000075031 0.702215027772976 0.775560609711725 0.775560609711725 0.775560609711725 0.363631147570911 0.775560609711725
Dolk ENSMUSG00000075419 0.384672302267076 0.577008453400614 0.762100360299702 0.762100360299702 0.116265430850263 0.34879629255079
Dohh ENSMUSG00000078440 0.850721744111585 0.850721744111585 0.57113445032749 0.850721744111585 0.455625354715449 0.850721744111585
Eif5a ENSMUSG00000078812 0.514300775319626 0.771451162979439 0.778911768167544 0.778911768167544 0.298599969973533 0.771451162979439
Dpm1 ENSMUSG00000078919 0.142830916318171 0.214246374477256 0.113190884633071 0.214246374477256 0.514934023620345 0.514934023620345
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1
Rps13 ENSMUSG00000090862 0.577829325134931 0.577829325134931 0.514934023620345 0.577829325134931 0.120850531362929 0.362551594088788

Mitochondrial translation termination

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl2 ENSMUSG00000002767 0.178901132102685 0.536703396308054 0.575536202757516 0.575536202757516 0.395196379647461 0.575536202757516
Mrpl4 ENSMUSG00000003299 0.287873078401389 0.78180291566155 0.78180291566155 0.78180291566155 0.637274134311157 0.78180291566155
Mrps25 ENSMUSG00000014551 0.780851835278818 0.780851835278818 0.0947558980989551 0.284267694296865 0.643359829732651 0.780851835278818
Mrpl45 ENSMUSG00000018882 0.346899083932133 0.520348625898199 0.298599969973533 0.520348625898199 0.926441990075769 0.926441990075769
Mrps24 ENSMUSG00000020477 0.399548817627028 0.599323226440542 0.213307944885796 0.599323226440542 0.642366752097095 0.642366752097095
Eral1 ENSMUSG00000020832 0.514300775319626 0.577259514257969 0.577259514257969 0.577259514257969 0.297095062262363 0.577259514257969
Mrpl36 ENSMUSG00000021607 0.852504981253341 0.852504981253341 0.348008842235184 0.852504981253341 0.711034989117171 0.852504981253341
Mrp63 ENSMUSG00000021967 0.300095920620218 0.520348625898199 0.346899083932133 0.520348625898199 0.853801250889739 0.853801250889739
Mrpl14 ENSMUSG00000023939 0.249907451332337 0.451840588205062 0.398108175780842 0.451840588205062 0.451840588205062 0.451840588205062
Mrpl28 ENSMUSG00000024181 0.242231702094921 0.388491809581663 0.319786844594194 0.388491809581663 0.388491809581663 0.388491809581663
Mrpl16 ENSMUSG00000024683 0.253294730253595 0.379942095380392 0.0432318933800775 0.129695680140233 0.447621891168214 0.447621891168214
Mrpl44 ENSMUSG00000026248 0.638824656785692 0.778911768167544 0.397384062266614 0.778911768167544 0.778911768167544 0.778911768167544
Mrpl53 ENSMUSG00000030037 0.706616781330066 0.706616781330066 0.638310022345193 0.706616781330066 0.513665062682276 0.706616781330066
Mrpl17 ENSMUSG00000030879 0.638310022345193 0.926658283600152 0.926658283600152 0.926658283600152 0.777922216623952 0.926658283600152
Mrpl54 ENSMUSG00000034932 0.255530331334266 0.599323226440542 0.709375484777034 0.709375484777034 0.399548817627028 0.599323226440542
Mrpl41 ENSMUSG00000036850 0.17924968721805 0.53774906165415 0.780851835278818 0.780851835278818 0.711034989117171 0.780851835278818
Mrpl55 ENSMUSG00000036860 0.853480389728993 0.853480389728993 0.253294730253594 0.759884190760783 0.514300775319626 0.771451162979439
Mrps26 ENSMUSG00000037740 0.252920381501207 0.75876114450362 0.636229315311352 0.7802108304765 0.7802108304765 0.7802108304765
Mrps34 ENSMUSG00000038880 0.342026805366747 0.852175490580835 0.706616781330066 0.852175490580835 0.852175490580835 0.852175490580835
Mrps27 ENSMUSG00000041632 0.096425230538547 0.289275691615641 0.254787123615605 0.343537039781257 0.343537039781257 0.343537039781257
Mrps12 ENSMUSG00000045948 0.567513221841557 0.567513221841557 0.0432318933800775 0.129695680140232 0.446194239410717 0.567513221841557
Mrps7 ENSMUSG00000046756 0.578113371816017 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Mrps36 ENSMUSG00000061474 0.456305241393103 0.456305241393103 0.180293335960318 0.270440003940477 0.0375110574079901 0.11253317222397

Mitochondrial translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl2 ENSMUSG00000002767 0.178901132102685 0.536703396308054 0.575536202757516 0.575536202757516 0.395196379647461 0.575536202757516
Mrpl4 ENSMUSG00000003299 0.287873078401389 0.78180291566155 0.78180291566155 0.78180291566155 0.637274134311157 0.78180291566155
Mrps25 ENSMUSG00000014551 0.780851835278818 0.780851835278818 0.0947558980989551 0.284267694296865 0.643359829732651 0.780851835278818
Mrpl45 ENSMUSG00000018882 0.346899083932133 0.520348625898199 0.298599969973533 0.520348625898199 0.926441990075769 0.926441990075769
Mrps24 ENSMUSG00000020477 0.399548817627028 0.599323226440542 0.213307944885796 0.599323226440542 0.642366752097095 0.642366752097095
Eral1 ENSMUSG00000020832 0.514300775319626 0.577259514257969 0.577259514257969 0.577259514257969 0.297095062262363 0.577259514257969
Mrpl36 ENSMUSG00000021607 0.852504981253341 0.852504981253341 0.348008842235184 0.852504981253341 0.711034989117171 0.852504981253341
Mrp63 ENSMUSG00000021967 0.300095920620218 0.520348625898199 0.346899083932133 0.520348625898199 0.853801250889739 0.853801250889739
Mrpl14 ENSMUSG00000023939 0.249907451332337 0.451840588205062 0.398108175780842 0.451840588205062 0.451840588205062 0.451840588205062
Mrpl28 ENSMUSG00000024181 0.242231702094921 0.388491809581663 0.319786844594194 0.388491809581663 0.388491809581663 0.388491809581663
Mrpl16 ENSMUSG00000024683 0.253294730253595 0.379942095380392 0.0432318933800775 0.129695680140233 0.447621891168214 0.447621891168214
Mrpl44 ENSMUSG00000026248 0.638824656785692 0.778911768167544 0.397384062266614 0.778911768167544 0.778911768167544 0.778911768167544
Mrpl53 ENSMUSG00000030037 0.706616781330066 0.706616781330066 0.638310022345193 0.706616781330066 0.513665062682276 0.706616781330066
Mrpl17 ENSMUSG00000030879 0.638310022345193 0.926658283600152 0.926658283600152 0.926658283600152 0.777922216623952 0.926658283600152
Mrpl54 ENSMUSG00000034932 0.255530331334266 0.599323226440542 0.709375484777034 0.709375484777034 0.399548817627028 0.599323226440542
Mrpl41 ENSMUSG00000036850 0.17924968721805 0.53774906165415 0.780851835278818 0.780851835278818 0.711034989117171 0.780851835278818
Mrpl55 ENSMUSG00000036860 0.853480389728993 0.853480389728993 0.253294730253594 0.759884190760783 0.514300775319626 0.771451162979439
Mrps26 ENSMUSG00000037740 0.252920381501207 0.75876114450362 0.636229315311352 0.7802108304765 0.7802108304765 0.7802108304765
Mrps34 ENSMUSG00000038880 0.342026805366747 0.852175490580835 0.706616781330066 0.852175490580835 0.852175490580835 0.852175490580835
Mrps27 ENSMUSG00000041632 0.096425230538547 0.289275691615641 0.254787123615605 0.343537039781257 0.343537039781257 0.343537039781257
Mrps12 ENSMUSG00000045948 0.567513221841557 0.567513221841557 0.0432318933800775 0.129695680140232 0.446194239410717 0.567513221841557
Mrps7 ENSMUSG00000046756 0.578113371816017 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Mrps36 ENSMUSG00000061474 0.456305241393103 0.456305241393103 0.180293335960318 0.270440003940477 0.0375110574079901 0.11253317222397

ER to Golgi Anterograde Transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Translation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mrpl2 ENSMUSG00000002767 0.178901132102685 0.536703396308054 0.575536202757516 0.575536202757516 0.395196379647461 0.575536202757516
Eif2b5 ENSMUSG00000003235 0.0953125666339397 0.174398146275395 0.766080166042519 0.766080166042519 0.116265430850263 0.174398146275395
Mrpl4 ENSMUSG00000003299 0.287873078401389 0.78180291566155 0.78180291566155 0.78180291566155 0.637274134311157 0.78180291566155
Rps9 ENSMUSG00000006333 0.347639524025037 0.926550375688041 0.643853282854191 0.926550375688041 0.926550375688041 0.926550375688041
Mrps25 ENSMUSG00000014551 0.780851835278818 0.780851835278818 0.0947558980989551 0.284267694296865 0.643359829732651 0.780851835278818
Eif3d ENSMUSG00000016554 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.119631084167592 0.317766870502212
Mrpl45 ENSMUSG00000018882 0.346899083932133 0.520348625898199 0.298599969973533 0.520348625898199 0.926441990075769 0.926441990075769
Mrps24 ENSMUSG00000020477 0.399548817627028 0.599323226440542 0.213307944885796 0.599323226440542 0.642366752097095 0.642366752097095
Srp68 ENSMUSG00000020780 0.511742979522636 0.767614469283954 0.778911768167544 0.778911768167544 0.146800541856249 0.440401625568746
Eral1 ENSMUSG00000020832 0.514300775319626 0.577259514257969 0.577259514257969 0.577259514257969 0.297095062262363 0.577259514257969
Mrpl36 ENSMUSG00000021607 0.852504981253341 0.852504981253341 0.348008842235184 0.852504981253341 0.711034989117171 0.852504981253341
Mrp63 ENSMUSG00000021967 0.300095920620218 0.520348625898199 0.346899083932133 0.520348625898199 0.853801250889739 0.853801250889739
Mrpl14 ENSMUSG00000023939 0.249907451332337 0.451840588205062 0.398108175780842 0.451840588205062 0.451840588205062 0.451840588205062
Mrpl28 ENSMUSG00000024181 0.242231702094921 0.388491809581663 0.319786844594194 0.388491809581663 0.388491809581663 0.388491809581663
Mrpl16 ENSMUSG00000024683 0.253294730253595 0.379942095380392 0.0432318933800775 0.129695680140233 0.447621891168214 0.447621891168214
Rplp2 ENSMUSG00000025508 0.146800541856249 0.440401625568746 0.297848640636702 0.446772960955053 0.709375484777034 0.709375484777034
Mrpl44 ENSMUSG00000026248 0.638824656785692 0.778911768167544 0.397384062266614 0.778911768167544 0.778911768167544 0.778911768167544
Mrpl53 ENSMUSG00000030037 0.706616781330066 0.706616781330066 0.638310022345193 0.706616781330066 0.513665062682276 0.706616781330066
Rpl28 ENSMUSG00000030432 0.398108175780842 0.78148726569172 0.57466664340579 0.78148726569172 0.78148726569172 0.78148726569172
Mrpl17 ENSMUSG00000030879 0.638310022345193 0.926658283600152 0.926658283600152 0.926658283600152 0.777922216623952 0.926658283600152
Eif3f ENSMUSG00000031029 0.0947558980989551 0.284267694296865 0.9255572759333 0.9255572759333 0.395196379647461 0.592794569471191
Eif3l ENSMUSG00000033047 0.7048795965722 0.711034989117171 0.711034989117171 0.711034989117171 0.236337185850513 0.70901155755154
Mrpl54 ENSMUSG00000034932 0.255530331334266 0.599323226440542 0.709375484777034 0.709375484777034 0.399548817627028 0.599323226440542
Eef2 ENSMUSG00000034994 0.249907451332337 0.374861176998506 0.77858338846904 0.77858338846904 0.0741204440774083 0.222361332232225
Mrpl41 ENSMUSG00000036850 0.17924968721805 0.53774906165415 0.780851835278818 0.780851835278818 0.711034989117171 0.780851835278818
Mrpl55 ENSMUSG00000036860 0.853480389728993 0.853480389728993 0.253294730253594 0.759884190760783 0.514300775319626 0.771451162979439
Mrps26 ENSMUSG00000037740 0.252920381501207 0.75876114450362 0.636229315311352 0.7802108304765 0.7802108304765 0.7802108304765
Trmt112 ENSMUSG00000038812 0.926496242814507 0.926496242814507 0.120241108790035 0.222666377674426 0.148444251782951 0.222666377674426
Mrps34 ENSMUSG00000038880 0.342026805366747 0.852175490580835 0.706616781330066 0.852175490580835 0.852175490580835 0.852175490580835
Eif4h ENSMUSG00000040731 0.119631084167592 0.221188136557642 0.778911768167544 0.778911768167544 0.147458757705094 0.221188136557642
Mrps27 ENSMUSG00000041632 0.096425230538547 0.289275691615641 0.254787123615605 0.343537039781257 0.343537039781257 0.343537039781257
Rps2 ENSMUSG00000044533 0.140165358447409 0.220200812784373 0.146800541856249 0.220200812784373 0.779238691542963 0.779238691542963
Mrps12 ENSMUSG00000045948 0.567513221841557 0.567513221841557 0.0432318933800775 0.129695680140232 0.446194239410717 0.567513221841557
Mrps7 ENSMUSG00000046756 0.578113371816017 0.711854160331342 0.576973746230334 0.711854160331342 0.711854160331342 0.711854160331342
Mrps36 ENSMUSG00000061474 0.456305241393103 0.456305241393103 0.180293335960318 0.270440003940477 0.0375110574079901 0.11253317222397
Gspt1 ENSMUSG00000062203 0.0325051220296005 0.0975153660888015 0.926658283600152 1 1 1
Srp54a ENSMUSG00000073079 0.0562022152993845 0.168606645898153 0.577829325134931 0.866743987702397 0.92622377157404 0.92622377157404
Rps13 ENSMUSG00000090862 0.577829325134931 0.577829325134931 0.514934023620345 0.577829325134931 0.120850531362929 0.362551594088788

Transport to the Golgi and subsequent modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Mgat1 ENSMUSG00000020346 0.0240620856673909 0.0721862570021728 0.711854160331342 1 1 1
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Fuca1 ENSMUSG00000028673 0.643359829732651 0.643359829732651 0.397384062266614 0.643359829732651 0.514934023620345 0.643359829732651
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Asparagine N-linked glycosylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Ctsa ENSMUSG00000017760 0.77169240001909 0.926333123228344 0.926333123228344 0.926333123228344 0.6978446011211 0.926333123228344
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Mgat1 ENSMUSG00000020346 0.0240620856673909 0.0721862570021728 0.711854160331342 1 1 1
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Gne ENSMUSG00000028479 0.777255087907932 0.777255087907932 0.569937449249116 0.777255087907932 0.0441715176243983 0.132514552873195
Fuca1 ENSMUSG00000028673 0.643359829732651 0.643359829732651 0.397384062266614 0.643359829732651 0.514934023620345 0.643359829732651
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Fuk ENSMUSG00000033703 0.513026869856283 0.853694531487825 0.711034989117171 0.853694531487825 0.853694531487825 0.853694531487825
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Alg12 ENSMUSG00000035845 0.453570536021945 0.453570536021945 0.0701431284016184 0.210429385204855 0.398829756175299 0.453570536021945
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Alg1 ENSMUSG00000039427 0.641867098978197 0.781170242226513 0.148772260628989 0.446316781886968 0.781170242226513 0.781170242226513
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
St6galnac2 ENSMUSG00000057286 0.578113371816017 0.853694531487825 0.853694531487825 0.853694531487825 0.711854160331342 0.853694531487825
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Dolk ENSMUSG00000075419 0.384672302267076 0.577008453400614 0.762100360299702 0.762100360299702 0.116265430850263 0.34879629255079
Dpm1 ENSMUSG00000078919 0.142830916318171 0.214246374477256 0.113190884633071 0.214246374477256 0.514934023620345 0.514934023620345
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Gmpr ENSMUSG00000000253 0.344663224299303 0.643853282854191 0.514300775319626 0.643853282854191 0.643853282854191 0.643853282854191
Comt ENSMUSG00000000326 0.249907451332337 0.508817043656047 0.43283647035887 0.508817043656047 0.508817043656047 0.508817043656047
Ckb ENSMUSG00000001270 0.113498953177704 0.340496859533111 0.57466664340579 0.57466664340579 0.445116333668945 0.57466664340579
Prkd1 ENSMUSG00000002688 0.346527959006435 0.519791938509652 0.342405296020881 0.519791938509652 1 1
Stard3nl ENSMUSG00000003062 0.853801250889739 0.853801250889739 0.454600801949285 0.853801250889739 0.711034989117171 0.853801250889739
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Slc2a3 ENSMUSG00000003153 0.514934023620344 0.78148726569172 0.577259514257969 0.78148726569172 0.78148726569172 0.78148726569172
Nosip ENSMUSG00000003421 0.023800255149993 0.0714007654499789 0.711854160331342 0.711854160331342 0.642366752097095 0.711854160331342
Psap ENSMUSG00000004207 0.178901132102684 0.268351698154027 0.638824656785692 0.638824656785692 0.11595859961889 0.268351698154027
Eno2 ENSMUSG00000004267 0.576973746230334 0.710208797518812 0.710208797518812 0.710208797518812 0.577259514257969 0.710208797518812
Lbr ENSMUSG00000004880 0.852940894477647 0.852940894477647 0.347639524025037 0.852940894477647 0.710001140920767 0.852940894477647
Txn2 ENSMUSG00000005354 0.132079352483269 0.396238057449806 0.509144723230069 0.569937449249116 0.569937449249116 0.569937449249116
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Shpk ENSMUSG00000005951 0.179945789077372 0.539837367232115 0.643359829732651 0.643359829732651 0.453225835454266 0.643359829732651
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Aprt ENSMUSG00000006589 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152 0.853694531487825 0.926658283600152
Slc5a6 ENSMUSG00000006641 0.343537039781257 0.712057867818062 0.712057867818062 0.712057867818062 0.577829325134931 0.712057867818062
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Cers4 ENSMUSG00000008206 0.710001140920767 0.710001140920767 0.0432318933800775 0.129695680140232 0.299349060054896 0.449023590082344
Fut1 ENSMUSG00000008461 0.232742460142726 0.232742460142726 0.232742460142726 0.232742460142726 0.00483879841783549 0.0145163952535065
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Slc25a11 ENSMUSG00000014606 0.576112968612194 0.710001140920767 0.710001140920767 0.710001140920767 0.253294730253595 0.710001140920767
Lta4h ENSMUSG00000015889 0.709375484777034 0.926333123228344 0.642864324224729 0.926333123228344 0.926333123228344 0.926333123228344
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Ctsa ENSMUSG00000017760 0.77169240001909 0.926333123228344 0.926333123228344 0.926333123228344 0.6978446011211 0.926333123228344
Acadvl ENSMUSG00000018574 0.348008842235184 0.926003599371281 0.780851835278817 0.926003599371281 0.926003599371281 0.926003599371281
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Fdxr ENSMUSG00000018861 0.575536202757516 0.852504981253341 0.852504981253341 0.852504981253341 0.643853282854191 0.852504981253341
Mdh2 ENSMUSG00000019179 0.708534948098331 0.708745765211584 0.447621891168214 0.708745765211584 0.708745765211584 0.708745765211584
Slc6a8 ENSMUSG00000019558 0.575536202757516 0.853372965654504 0.256271555563966 0.768814666691898 0.853372965654504 0.853372965654504
Gamt ENSMUSG00000020150 0.148115998140416 0.222173997210623 0.0230207752632622 0.0690623257897866 0.511742979522636 0.511742979522636
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Hmmr ENSMUSG00000020330 0.643359829732651 0.643359829732651 0.00719286546902976 0.0215785964070893 0.514934023620345 0.643359829732651
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Apob ENSMUSG00000020609 0.853372965654504 0.853372965654504 0.0577292451600846 0.173187735480254 0.577829325134931 0.853372965654504
Nup85 ENSMUSG00000020739 0.454600801949285 0.683438032073173 0.455625354715448 0.683438032073173 0.852832278580641 0.852832278580641
Galk1 ENSMUSG00000020766 0.254414773803597 0.450143880930326 0.578113371816017 0.578113371816017 0.300095920620217 0.450143880930326
Plcd3 ENSMUSG00000020937 0.119631084167592 0.179446626251388 0.710416009055326 0.710416009055326 0.0964252305385472 0.179446626251388
Glrx5 ENSMUSG00000021102 0.451840588205062 0.767614469283954 0.78180291566155 0.78180291566155 0.511742979522636 0.767614469283954
Abcd4 ENSMUSG00000021240 0.399548817627028 0.599323226440542 0.397384062266614 0.599323226440542 0.707899741868332 0.707899741868332
Ptdss1 ENSMUSG00000021518 0.640861491578951 0.640861491578951 0.044926265292481 0.134778795877443 0.345037391052887 0.51755608657933
Ephx2 ENSMUSG00000022040 0.0958690133561599 0.28760704006848 0.853801250889739 0.853801250889739 0.575824878403157 0.853801250889739
Gm21685 ENSMUSG00000022066 0.511742979522636 0.767614469283954 0.178901132102685 0.536703396308054 0.7802108304765 0.7802108304765
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Amacr ENSMUSG00000022244 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041 0.7802108304765 0.926550375688041
Aco2 ENSMUSG00000022477 0.33116978622016 0.49675467933024 0.578113371816017 0.578113371816017 0.168646652367079 0.49675467933024
Gpt ENSMUSG00000022546 0.214764523938594 0.644293571815782 0.641867098978198 0.78148726569172 0.78148726569172 0.78148726569172
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Oplah ENSMUSG00000022562 0.18064054691103 0.541921640733091 0.511742979522636 0.711240436189781 0.711240436189781 0.711240436189781
Naprt1 ENSMUSG00000022574 0.45596561163947 0.683948417459205 0.148772260628989 0.446316781886968 0.853907737111068 0.853907737111068
Bsg ENSMUSG00000023175 0.450794830295118 0.676192245442677 0.711650020253571 0.711650020253571 0.11993617140438 0.359808514213139
Eci1 ENSMUSG00000024132 0.058823267388015 0.176469802164045 0.710001140920767 0.710001140920767 0.640861491578951 0.710001140920767
Cyp4f14 ENSMUSG00000024292 0.300095920620218 0.34837756124189 0.254414773803597 0.34837756124189 0.34837756124189 0.34837756124189
Cndp2 ENSMUSG00000024644 0.777255087907932 0.777255087907932 0.576973746230334 0.777255087907932 0.505169133438821 0.777255087907932
Pitpnm1 ENSMUSG00000024851 0.926550375688041 0.926550375688041 0.640355507848752 0.926550375688041 0.179945789077372 0.539837367232115
Pi4k2a ENSMUSG00000025178 0.297095062262362 0.445642593393544 0.707899741868332 0.707899741868332 0.0746183450292887 0.223855035087866
Abcc2 ENSMUSG00000025194 0.0748673451455297 0.0748673451455297 0.023800255149993 0.0357003827249895 0.0162664168407234 0.0357003827249895
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Ptdss2 ENSMUSG00000025495 0.297848640636702 0.578113371816017 0.578113371816017 0.578113371816017 0.45596561163947 0.578113371816017
Taldo1 ENSMUSG00000025503 0.300095920620218 0.900287761860654 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Sumf2 ENSMUSG00000025538 0.21549027811633 0.400265374208515 0.297095062262362 0.400265374208515 0.400265374208515 0.400265374208515
Pfkfb4 ENSMUSG00000025648 0.642864324224729 0.642864324224729 0.0231500557096833 0.0694501671290498 0.454600801949285 0.642864324224729
Hadha ENSMUSG00000025745 0.299349060054895 0.898047180164686 1 1 0.78148726569172 1
Pycr2 ENSMUSG00000026520 0.511097249598474 0.643853282854191 0.643853282854191 0.643853282854191 0.637274134311157 0.643853282854191
Mmadhc ENSMUSG00000026766 0.573791743469336 0.637793186752488 0.290984282074805 0.637793186752488 0.637793186752488 0.637793186752488
Ptges2 ENSMUSG00000026820 0.710001140920767 0.710001140920767 0.710001140920767 0.710001140920767 0.573498913947369 0.710001140920767
Fam73b ENSMUSG00000026858 0.708323672944427 0.926658283600152 0.926658283600152 0.926658283600152 0.341647690705446 0.926658283600152
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Stard7 ENSMUSG00000027367 0.634645058916812 0.636229315311352 0.108554321668226 0.325662965004679 0.636229315311352 0.636229315311352
Pla2g12a ENSMUSG00000027999 0.256271555563966 0.384407333345949 0.78180291566155 0.78180291566155 0.0964252305385474 0.289275691615642
Txn1 ENSMUSG00000028367 0.7802108304765 0.7802108304765 0.575824878403157 0.7802108304765 0.454600801949285 0.7802108304765
Alad ENSMUSG00000028393 0.246861959455465 0.370292939183197 0.57113445032749 0.57113445032749 0.118409250205154 0.355227750615461
Gba2 ENSMUSG00000028467 0.0743693776059065 0.223108132817719 0.255530331334266 0.383295497001398 0.45596561163947 0.45596561163947
Ctps ENSMUSG00000028633 0.641867098978198 0.641867098978198 0.17610058307789 0.52830174923367 0.398829756175299 0.598244634262948
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Gale ENSMUSG00000028671 0.118409250205154 0.355227750615461 0.851732715229127 0.851732715229127 0.643359829732651 0.851732715229127
Hmgcl ENSMUSG00000028672 0.398108175780842 0.926550375688041 0.926550375688041 0.926550375688041 0.707899741868332 0.926550375688041
Akr1a1 ENSMUSG00000028692 0.576973746230334 0.576973746230334 0.344663224299303 0.51755608657933 0.345037391052887 0.51755608657933
Aldh4a1 ENSMUSG00000028737 0.45596561163947 0.45596561163947 0.213307944885796 0.383851786434905 0.255901190956604 0.383851786434905
Ak2 ENSMUSG00000028792 0.576973746230334 1 1 1 0.781170242226513 1
Nadk ENSMUSG00000029063 0.453225835454266 0.573791743469336 0.509144723230069 0.573791743469336 0.573791743469336 0.573791743469336
Gltpd1 ENSMUSG00000029073 0.392985378348026 0.589478067522039 0.631413595275176 0.631413595275176 0.291756209988535 0.589478067522039
Pgm1 ENSMUSG00000029171 0.0116356061791785 0.0349068185375355 0.0451153644990945 0.0676730467486417 0.255901190956604 0.255901190956604
Lias ENSMUSG00000029199 0.513665062682276 0.642864324224729 0.343537039781257 0.642864324224729 0.642864324224729 0.642864324224729
Enoph1 ENSMUSG00000029326 0.450444934184774 0.675667401277161 0.924872384323464 0.924872384323464 0.345037391052887 0.675667401277161
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Acads ENSMUSG00000029545 0.0449262652924809 0.114916742971844 0.926658283600152 0.926658283600152 0.0766111619812296 0.114916742971844
Sdsl ENSMUSG00000029596 0.514934023620344 0.514934023620344 0.00719286546902976 0.0215785964070893 0.17750354896016 0.26625532344024
Cyp3a25 ENSMUSG00000029630 0.701989711806957 0.701989711806957 0.334323804341914 0.501485706512871 0.112574347985553 0.337723043956658
Aass ENSMUSG00000029695 1 1 0.0753654386865988 0.226096316059796 0.710001140920767 1
Gnb2 ENSMUSG00000029713 0.024062085667391 0.0721862570021729 0.455625354715449 0.683438032073173 0.779238691542963 0.779238691542963
Mtmr14 ENSMUSG00000030269 1 1 0.21549027811633 0.64647083434899 0.926003599371282 1
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Cdipt ENSMUSG00000030682 0.573498913947369 0.573498913947369 0.505838378028518 0.573498913947369 0.295581119060361 0.573498913947369
Aldoa ENSMUSG00000030695 0.513665062682276 0.513665062682276 0.505838378028518 0.513665062682276 0.148115998140415 0.444347994421246
Lipt2 ENSMUSG00000030725 0.711650020253571 0.926550375688041 0.926550375688041 0.926550375688041 0.398829756175299 0.926550375688041
Dgat2 ENSMUSG00000030747 0.09586901335616 0.28760704006848 0.641867098978198 0.641867098978198 0.45596561163947 0.641867098978198
Bcat2 ENSMUSG00000030826 0.346527959006435 0.456305241393103 0.298599969973533 0.456305241393103 0.456305241393103 0.456305241393103
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Lhpp ENSMUSG00000030946 0.0753654386865988 0.226096316059796 1 1 0.779888212132595 1
Slc25a15 ENSMUSG00000031482 0.853907737111068 1 0.5155648232968 1 1 1
Agpat6 ENSMUSG00000031545 0.7802108304765 0.7802108304765 0.7802108304765 0.7802108304765 0.392985378348026 0.7802108304765
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Pla2g15 ENSMUSG00000031903 0.513665062682276 0.514934023620345 0.452880492349546 0.514934023620345 0.514934023620345 0.514934023620345
Cyb5b ENSMUSG00000031924 0.92589277149125 0.92589277149125 0.179945789077372 0.429454856264095 0.286303237509397 0.429454856264095
Slc37a4 ENSMUSG00000032114 0.211844580334808 0.317766870502212 0.173632433887832 0.317766870502212 0.449391287230099 0.449391287230099
Hmbs ENSMUSG00000032126 0.511742979522636 0.852065168704833 0.576973746230334 0.852065168704833 0.852065168704833 0.852065168704833
Gnb5 ENSMUSG00000032192 0.179945789077372 0.539837367232115 0.712057867818062 0.926658283600152 0.926658283600152 0.926658283600152
Ip6k1 ENSMUSG00000032594 0.926658283600152 0.926658283600152 0.853372965654504 0.926658283600152 0.511742979522636 0.926658283600152
Slc25a20 ENSMUSG00000032602 0.146141353215796 0.438424059647387 0.578396848531894 0.578396848531894 0.514300775319626 0.578396848531894
Nt5m ENSMUSG00000032615 0.168646652367079 0.384672302267076 0.346899083932133 0.384672302267076 0.384672302267076 0.384672302267076
Slc16a1 ENSMUSG00000032902 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501 0.216214347033995 0.648643041101984
Pfkm ENSMUSG00000033065 0.146141353215796 0.37938057225181 0.925444427431699 0.925444427431699 0.252920381501207 0.37938057225181
Gstt2 ENSMUSG00000033318 0.400265374208515 0.400265374208515 0.400265374208515 0.400265374208515 0.17924968721805 0.400265374208515
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Dak ENSMUSG00000034371 0.178901132102685 0.505838378028518 0.505838378028518 0.505838378028518 0.395928178642446 0.505838378028518
Gna11 ENSMUSG00000034781 0.346899083932133 0.5203486258982 0.926003599371281 0.926003599371281 0.17924968721805 0.5203486258982
Oaz1 ENSMUSG00000035242 0.384672302267076 0.573791743469336 0.573791743469336 0.573791743469336 0.449391287230099 0.573791743469336
Tmem55b ENSMUSG00000035953 0.711650020253571 0.711650020253571 0.576973746230334 0.711650020253571 0.578113371816017 0.711650020253571
Sbf1 ENSMUSG00000036529 0.21549027811633 0.438788713627291 0.452880492349546 0.452880492349546 0.29252580908486 0.438788713627291
Acaa2 ENSMUSG00000036880 0.0953125666339398 0.285937699901819 0.926333123228344 0.926333123228344 0.709375484777034 0.926333123228344
Osbpl5 ENSMUSG00000037606 0.706616781330066 0.706616781330066 0.7048795965722 0.706616781330066 0.17610058307789 0.528301749233671
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Chpf2 ENSMUSG00000038181 0.57466664340579 0.861999965108685 0.57113445032749 0.861999965108685 1 1
Pdss2 ENSMUSG00000038240 0.77858338846904 0.926333123228344 0.926333123228344 0.926333123228344 0.435508086002014 0.926333123228344
Bphl ENSMUSG00000038286 0.171859370212435 0.515578110637305 1 1 0.642366752097095 0.963550128145642
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Mboat1 ENSMUSG00000038732 0.454600801949285 0.576112968612194 0.576112968612194 0.576112968612194 0.344663224299303 0.576112968612194
Trmt112 ENSMUSG00000038812 0.926496242814507 0.926496242814507 0.120241108790035 0.222666377674426 0.148444251782951 0.222666377674426
Ndst2 ENSMUSG00000039308 0.454600801949285 0.681901202923927 0.398829756175299 0.681901202923927 0.853801250889739 0.853801250889739
Dcxr ENSMUSG00000039450 0.511742979522636 1 1 1 0.926550375688041 1
Coq10a ENSMUSG00000039914 0.0443599545252852 0.133079863575856 0.711854160331342 0.711854160331342 0.711240436189781 0.711854160331342
Maob ENSMUSG00000040147 0.84992097596507 0.84992097596507 0.573498913947369 0.84992097596507 0.447265995733381 0.84992097596507
Pck2 ENSMUSG00000040618 0.780851835278818 0.780851835278818 0.243396309647536 0.365094464471304 0.18064054691103 0.365094464471304
Oaz2 ENSMUSG00000040652 0.572616808177226 0.706616781330066 0.706616781330066 0.706616781330066 0.398829756175299 0.706616781330066
Hsd3b7 ENSMUSG00000042289 0.640355507848752 0.926550375688041 0.926550375688041 0.926550375688041 0.926333123228344 0.926550375688041
Flad1 ENSMUSG00000042642 0.0443599545252852 0.133079863575856 0.45596561163947 0.639337105615664 0.639337105615664 0.639337105615664
Tst ENSMUSG00000044986 0.0116356061791785 0.0349068185375355 0.711650020253571 0.711650020253571 0.451840588205062 0.677760882307593
Nudt18 ENSMUSG00000045211 0.120850531362929 0.307762054892242 0.205174703261494 0.307762054892242 0.576973746230334 0.576973746230334
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Fitm2 ENSMUSG00000048486 0.926550375688041 0.926550375688041 0.452880492349546 0.679320738524319 0.252545530864481 0.679320738524319
B3gnt2 ENSMUSG00000051650 0.25141795904251 0.447621891168214 0.348008842235184 0.447621891168214 0.447621891168214 0.447621891168214
Nup188 ENSMUSG00000052533 0.214037080764326 0.252545530864481 0.179249687218049 0.252545530864481 0.252545530864481 0.252545530864481
Acbd4 ENSMUSG00000056938 0.044926265292481 0.134778795877443 0.455625354715449 0.683438032073173 0.853480389728993 0.853480389728993
Slc44a2 ENSMUSG00000057193 0.294820734456232 0.711854160331342 0.711854160331342 0.711854160331342 0.643853282854191 0.711854160331342
Gapdh ENSMUSG00000057666 0.568427079091759 0.573205482926791 0.249528554620971 0.573205482926791 0.573205482926791 0.573205482926791
Cacnb2 ENSMUSG00000057914 0.294820734456232 0.521459286037555 0.56903312490074 0.56903312490074 0.347639524025037 0.521459286037555
Fdps ENSMUSG00000059743 0.297848640636702 0.297848640636702 0.0947558980989551 0.284267694296865 0.255901190956604 0.297848640636702
Gstp1 ENSMUSG00000060803 0.388491809581663 0.388491809581663 0.279118898313835 0.388491809581663 0.174692232033629 0.388491809581663
Impdh2 ENSMUSG00000062867 0.341647690705446 0.592794569471191 0.853049270252403 0.853049270252403 0.395196379647461 0.592794569471191
Eno1 ENSMUSG00000063524 0.513026869856283 0.640355507848752 0.575536202757516 0.640355507848752 0.640355507848752 0.640355507848752
Ppcdc ENSMUSG00000063849 0.00719286546902974 0.0215785964070892 0.0325051220296005 0.0487576830444007 0.92392908126717 0.92392908126717
Mocs1 ENSMUSG00000064120 0.120545895661628 0.361637686984883 0.779238691542963 0.851732715229127 0.851732715229127 0.851732715229127
Ethe1 ENSMUSG00000064254 0.926550375688041 1 1 1 1 1
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
B3galt4 ENSMUSG00000067370 0.148444251782951 0.323778784497071 0.852065168704833 0.852065168704833 0.215852522998048 0.323778784497071
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095
Acot1 ENSMUSG00000072949 0.0751163767602349 0.112674565140352 0.576687400573867 0.576687400573867 0.0167871584516597 0.0503614753549791
Cyp4f15 ENSMUSG00000073424 0.926441990075769 0.926441990075769 0.0763619660358786 0.229085898107636 0.578396848531894 0.867595272797842
Nme3 ENSMUSG00000073435 0.511742979522636 0.767614469283954 0.179249687218049 0.537749061654148 0.926550375688041 0.926550375688041
Fdx1l ENSMUSG00000079677 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.5155648232968 0.7733472349452
Ak9 ENSMUSG00000091415 0.255901190956604 0.767703572869812 0.926550375688041 0.926550375688041 0.642864324224729 0.926550375688041
Vkorc1 ENSMUSG00000096145 0.642366752097095 0.642366752097095 0.17610058307789 0.52830174923367 0.640861491578951 0.642366752097095

COPI-mediated anterograde transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Coq10a ENSMUSG00000039914 0.0443599545252852 0.133079863575856 0.711854160331342 0.711854160331342 0.711240436189781 0.711854160331342
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Post-translational protein modification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo7 ENSMUSG00000001786 0.299349060054895 0.853372965654504 0.853372965654504 0.853372965654504 0.852940894477647 0.853372965654504
Ltbp1 ENSMUSG00000001870 0.78180291566155 0.926333123228344 0.926333123228344 0.926333123228344 0.514934023620345 0.926333123228344
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Btbd6 ENSMUSG00000002803 0.0761127945805735 0.22833838374172 0.774871910813158 0.774871910813158 0.255530331334266 0.383295497001398
Paf1 ENSMUSG00000003437 0.926441990075769 0.926441990075769 0.0969812105731562 0.290943631719469 0.576973746230334 0.865460619345501
Cul3 ENSMUSG00000004364 0.0321889748775514 0.0620489870967841 0.0413659913978561 0.0620489870967841 0.0753654386865988 0.0753654386865988
Pex5 ENSMUSG00000005069 0.924872384323463 1 1 1 0.77858338846904 1
Fbxo11 ENSMUSG00000005371 0.0113901882503033 0.0341705647509098 0.926333123228344 0.926333123228344 0.577259514257969 0.865889271386954
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Pigl ENSMUSG00000014245 0.449743164679353 0.710208797518812 0.710208797518812 0.710208797518812 0.63856761373451 0.710208797518812
Fbxw5 ENSMUSG00000015095 0.119631084167591 0.358893252502774 0.57466664340579 0.705968934865368 0.705968934865368 0.705968934865368
Actr8 ENSMUSG00000015971 0.853372965654504 1 1 1 0.45596561163947 1
Ube2a ENSMUSG00000016308 0.711854160331342 0.853801250889739 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Ctsa ENSMUSG00000017760 0.77169240001909 0.926333123228344 0.926333123228344 0.926333123228344 0.6978446011211 0.926333123228344
Hist1h2bc ENSMUSG00000018102 0.453225835454266 0.780851835278817 0.780851835278817 0.780851835278817 0.643359829732651 0.780851835278817
Pcgf2 ENSMUSG00000018537 0.297848640636702 0.446772960955053 0.216214347033995 0.446772960955053 1 1
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Arrb1 ENSMUSG00000018909 0.295581119060361 0.443371678590541 0.640861491578951 0.640861491578951 0.146800541856249 0.440401625568746
Fkbp8 ENSMUSG00000019428 0.0716332429957515 0.214899728987254 0.501782052576058 0.501782052576058 0.447621891168214 0.501782052576058
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Fbxw11 ENSMUSG00000020271 0.638824656785692 0.958236985178538 1 1 0.513665062682276 0.958236985178538
Mgat1 ENSMUSG00000020346 0.0240620856673909 0.0721862570021728 0.711854160331342 1 1 1
Apob ENSMUSG00000020609 0.853372965654504 0.853372965654504 0.0577292451600846 0.173187735480254 0.577829325134931 0.853372965654504
Nup85 ENSMUSG00000020739 0.454600801949285 0.683438032073173 0.455625354715448 0.683438032073173 0.852832278580641 0.852832278580641
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Dcaf4 ENSMUSG00000021222 0.0113089139751576 0.0339267419254727 0.255901190956604 0.348008842235184 0.348008842235184 0.348008842235184
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Tab1 ENSMUSG00000022414 0.117185073436597 0.351555220309791 0.711650020253571 0.711650020253571 0.456305241393103 0.684457862089655
Josd1 ENSMUSG00000022426 0.299349060054895 0.85117361048289 0.85117361048289 0.85117361048289 0.640861491578951 0.85117361048289
Hdac7 ENSMUSG00000022475 0.453225835454266 0.679838753181399 0.708534948098331 0.708534948098331 0.398829756175299 0.679838753181399
Gpaa1 ENSMUSG00000022561 0.146141353215796 0.438424059647387 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Fstl1 ENSMUSG00000022816 0.343537039781257 0.683948417459205 1 1 0.45596561163947 0.683948417459205
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Spsb3 ENSMUSG00000024160 0.0441715176243982 0.132514552873195 0.925444427431699 0.925444427431699 0.119631084167592 0.179446626251387
Adamts10 ENSMUSG00000024299 0.398108175780842 0.770497594023414 0.853049270252403 0.853049270252403 0.513665062682276 0.770497594023414
Ddb1 ENSMUSG00000024740 0.509144723230069 0.763717084845103 0.92622377157404 0.92622377157404 0.295581119060361 0.763717084845103
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Fbxl15 ENSMUSG00000025226 0.57466664340579 0.853801250889739 0.0936419271039908 0.280925781311972 0.853801250889739 0.853801250889739
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Sumf2 ENSMUSG00000025538 0.21549027811633 0.400265374208515 0.297095062262362 0.400265374208515 0.400265374208515 0.400265374208515
Rab40c ENSMUSG00000025730 0.509798138101151 0.509798138101151 0.180293335960318 0.509798138101151 0.509798138101151 0.509798138101151
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Asb1 ENSMUSG00000026311 0.708534948098331 0.708534948098331 0.0743693776059065 0.223108132817719 0.294820734456232 0.442231101684348
Wdr5 ENSMUSG00000026917 0.249907451332337 0.681901202923927 0.454600801949285 0.681901202923927 0.708534948098331 0.708534948098331
Traf2 ENSMUSG00000026942 0.508488713161374 0.508488713161374 0.453225835454266 0.508488713161374 0.293293089483362 0.508488713161374
Commd9 ENSMUSG00000027163 0.00143725611474427 0.0043117683442328 0.711650020253571 0.711650020253571 0.513665062682276 0.711650020253571
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dcun1d1 ENSMUSG00000027708 0.0969812105731562 0.290943631719469 0.780851835278818 0.780851835278818 0.638310022345193 0.780851835278818
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Gne ENSMUSG00000028479 0.777255087907932 0.777255087907932 0.569937449249116 0.777255087907932 0.0441715176243983 0.132514552873195
Dph2 ENSMUSG00000028540 0.78180291566155 0.853049270252403 0.781170242226513 0.853049270252403 0.853049270252403 0.853049270252403
Fuca1 ENSMUSG00000028673 0.643359829732651 0.643359829732651 0.397384062266614 0.643359829732651 0.514934023620345 0.643359829732651
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ccdc22 ENSMUSG00000031143 0.345037391052887 0.7802108304765 0.7802108304765 0.7802108304765 0.778911768167544 0.7802108304765
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Brcc3 ENSMUSG00000031201 0.17750354896016 0.26625532344024 1 1 0.144820068500793 0.26625532344024
Usp10 ENSMUSG00000031826 0.179945789077372 0.539837367232116 0.711240436189781 0.712057867818062 0.712057867818062 0.712057867818062
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Qsox1 ENSMUSG00000033684 0.57113445032749 0.853694531487825 0.853694531487825 0.853694531487825 0.0733738589968007 0.220121576990402
Fuk ENSMUSG00000033703 0.513026869856283 0.853694531487825 0.711034989117171 0.853694531487825 0.853694531487825 0.853694531487825
Vhl ENSMUSG00000033933 0.299349060054895 0.898047180164686 1 1 0.708323672944427 1
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Rab24 ENSMUSG00000034789 0.119631084167591 0.179446626251387 0.213307944885796 0.213307944885796 0.0535981760208403 0.160794528062521
Eef2 ENSMUSG00000034994 0.249907451332337 0.374861176998506 0.77858338846904 0.77858338846904 0.0741204440774083 0.222361332232225
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Eva1a ENSMUSG00000035104 0.297848640636702 0.78180291566155 0.78180291566155 0.78180291566155 0.642864324224729 0.78180291566155
Fam175a ENSMUSG00000035234 0.509144723230069 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Alg12 ENSMUSG00000035845 0.453570536021945 0.453570536021945 0.0701431284016184 0.210429385204855 0.398829756175299 0.453570536021945
Kin ENSMUSG00000037262 0.453570536021945 0.7802108304765 0.703333998861023 0.7802108304765 0.7802108304765 0.7802108304765
Ctbp1 ENSMUSG00000037373 0.148115998140415 0.377126938563765 0.577259514257969 0.577259514257969 0.25141795904251 0.377126938563765
Mcrs1 ENSMUSG00000037570 0.162867964743396 0.488603894230187 0.711650020253571 0.711650020253571 0.706831781264721 0.711650020253571
Usp5 ENSMUSG00000038429 0.249907451332337 0.438889219142351 0.438889219142351 0.438889219142351 0.334715083204387 0.438889219142351
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Alg1 ENSMUSG00000039427 0.641867098978197 0.781170242226513 0.148772260628989 0.446316781886968 0.781170242226513 0.781170242226513
Mettl20 ENSMUSG00000039958 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041 0.926550375688041 0.926550375688041
Gyltl1b ENSMUSG00000040434 0.0969812105731563 0.290943631719469 0.216214347033995 0.324321520550992 0.577259514257969 0.577259514257969
Rabggta ENSMUSG00000040472 0.117185073436597 0.31000343112373 0.643359829732651 0.643359829732651 0.206668954082487 0.31000343112373
Fbxw4 ENSMUSG00000040913 0.297848640636702 0.446772960955053 0.254414773803597 0.446772960955053 0.709375484777034 0.709375484777034
Fbxo2 ENSMUSG00000041556 0.0766111619812296 0.229833485943689 0.703556284613037 0.703556284613037 0.577829325134931 0.703556284613037
Commd10 ENSMUSG00000042705 0.252545530864481 0.757636592593443 1 1 0.513026869856283 0.769540304784424
Taf10 ENSMUSG00000043866 0.0113089139751576 0.0339267419254727 0.848280005680805 0.848280005680805 0.702439833942814 0.848280005680805
Rps2 ENSMUSG00000044533 0.140165358447409 0.220200812784373 0.146800541856249 0.220200812784373 0.779238691542963 0.779238691542963
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Tada3 ENSMUSG00000048930 0.572616808177226 0.925669613555092 0.782117202022501 0.925669613555092 0.925669613555092 0.925669613555092
B3gnt2 ENSMUSG00000051650 0.25141795904251 0.447621891168214 0.348008842235184 0.447621891168214 0.447621891168214 0.447621891168214
Nup188 ENSMUSG00000052533 0.214037080764326 0.252545530864481 0.179249687218049 0.252545530864481 0.252545530864481 0.252545530864481
Sae1 ENSMUSG00000052833 0.392985378348026 0.589478067522039 0.638824656785692 0.638824656785692 0.338592117141989 0.589478067522039
Fbxo6 ENSMUSG00000055401 0.254414773803597 0.711034989117171 0.643359829732651 0.711034989117171 0.711034989117171 0.711034989117171
Klhl25 ENSMUSG00000055652 0.254414773803597 0.683438032073173 0.92622377157404 0.92622377157404 0.455625354715449 0.683438032073173
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Commd7 ENSMUSG00000056941 1 1 0.398108175780842 1 0.853372965654504 1
St6galnac2 ENSMUSG00000057286 0.578113371816017 0.853694531487825 0.853694531487825 0.853694531487825 0.711854160331342 0.853694531487825
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
H2afj ENSMUSG00000060032 0.0953125666339397 0.285937699901819 0.250285839267991 0.375428758901986 0.576112968612194 0.576112968612194
Dhps ENSMUSG00000060038 0.144157978128026 0.266780173889979 0.177853449259986 0.266780173889979 0.643359829732651 0.643359829732651
Nr1h2 ENSMUSG00000060601 0.346527959006435 0.519791938509652 0.252545530864481 0.519791938509652 0.573498913947369 0.573498913947369
Hist1h4i ENSMUSG00000060639 0.29252580908486 0.776919261684345 0.776919261684345 0.776919261684345 0.711034989117171 0.776919261684345
Hist1h4h ENSMUSG00000060981 0.78148726569172 1 1 1 0.5155648232968 1
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Suds3 ENSMUSG00000066900 0.25141795904251 0.377126938563765 0.772767153280156 0.772767153280156 0.178901132102685 0.377126938563765
Klhl21 ENSMUSG00000073700 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171 0.455625354715449 0.711034989117171
Hist1h2bb ENSMUSG00000075031 0.702215027772976 0.775560609711725 0.775560609711725 0.775560609711725 0.363631147570911 0.775560609711725
Dolk ENSMUSG00000075419 0.384672302267076 0.577008453400614 0.762100360299702 0.762100360299702 0.116265430850263 0.34879629255079
Dohh ENSMUSG00000078440 0.850721744111585 0.850721744111585 0.57113445032749 0.850721744111585 0.455625354715449 0.850721744111585
Eif5a ENSMUSG00000078812 0.514300775319626 0.771451162979439 0.778911768167544 0.778911768167544 0.298599969973533 0.771451162979439
Dpm1 ENSMUSG00000078919 0.142830916318171 0.214246374477256 0.113190884633071 0.214246374477256 0.514934023620345 0.514934023620345
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Neddylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo7 ENSMUSG00000001786 0.299349060054895 0.853372965654504 0.853372965654504 0.853372965654504 0.852940894477647 0.853372965654504
Btbd6 ENSMUSG00000002803 0.0761127945805735 0.22833838374172 0.774871910813158 0.774871910813158 0.255530331334266 0.383295497001398
Cul3 ENSMUSG00000004364 0.0321889748775514 0.0620489870967841 0.0413659913978561 0.0620489870967841 0.0753654386865988 0.0753654386865988
Fbxo11 ENSMUSG00000005371 0.0113901882503033 0.0341705647509098 0.926333123228344 0.926333123228344 0.577259514257969 0.865889271386954
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Fbxw5 ENSMUSG00000015095 0.119631084167591 0.358893252502774 0.57466664340579 0.705968934865368 0.705968934865368 0.705968934865368
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Fbxw11 ENSMUSG00000020271 0.638824656785692 0.958236985178538 1 1 0.513665062682276 0.958236985178538
Dcaf4 ENSMUSG00000021222 0.0113089139751576 0.0339267419254727 0.255901190956604 0.348008842235184 0.348008842235184 0.348008842235184
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Spsb3 ENSMUSG00000024160 0.0441715176243982 0.132514552873195 0.925444427431699 0.925444427431699 0.119631084167592 0.179446626251387
Ddb1 ENSMUSG00000024740 0.509144723230069 0.763717084845103 0.92622377157404 0.92622377157404 0.295581119060361 0.763717084845103
Fbxl15 ENSMUSG00000025226 0.57466664340579 0.853801250889739 0.0936419271039908 0.280925781311972 0.853801250889739 0.853801250889739
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Asb1 ENSMUSG00000026311 0.708534948098331 0.708534948098331 0.0743693776059065 0.223108132817719 0.294820734456232 0.442231101684348
Wdr5 ENSMUSG00000026917 0.249907451332337 0.681901202923927 0.454600801949285 0.681901202923927 0.708534948098331 0.708534948098331
Commd9 ENSMUSG00000027163 0.00143725611474427 0.0043117683442328 0.711650020253571 0.711650020253571 0.513665062682276 0.711650020253571
Dcun1d1 ENSMUSG00000027708 0.0969812105731562 0.290943631719469 0.780851835278818 0.780851835278818 0.638310022345193 0.780851835278818
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Ccdc22 ENSMUSG00000031143 0.345037391052887 0.7802108304765 0.7802108304765 0.7802108304765 0.778911768167544 0.7802108304765
Vhl ENSMUSG00000033933 0.299349060054895 0.898047180164686 1 1 0.708323672944427 1
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Fbxw4 ENSMUSG00000040913 0.297848640636702 0.446772960955053 0.254414773803597 0.446772960955053 0.709375484777034 0.709375484777034
Fbxo2 ENSMUSG00000041556 0.0766111619812296 0.229833485943689 0.703556284613037 0.703556284613037 0.577829325134931 0.703556284613037
Commd10 ENSMUSG00000042705 0.252545530864481 0.757636592593443 1 1 0.513026869856283 0.769540304784424
Fbxo6 ENSMUSG00000055401 0.254414773803597 0.711034989117171 0.643359829732651 0.711034989117171 0.711034989117171 0.711034989117171
Klhl25 ENSMUSG00000055652 0.254414773803597 0.683438032073173 0.92622377157404 0.92622377157404 0.455625354715449 0.683438032073173
Commd7 ENSMUSG00000056941 1 1 0.398108175780842 1 0.853372965654504 1
Klhl21 ENSMUSG00000073700 0.642864324224729 0.711034989117171 0.711034989117171 0.711034989117171 0.455625354715449 0.711034989117171

Respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Coq10a ENSMUSG00000039914 0.0443599545252852 0.133079863575856 0.711854160331342 0.711854160331342 0.711240436189781 0.711854160331342
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wdr77 ENSMUSG00000000561 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.712057867818062 0.782117202022501
Chtop ENSMUSG00000001017 0.852940894477647 1 1 1 0.853694531487825 1
Snrnp27 ENSMUSG00000001158 0.144820068500793 0.43446020550238 0.573205482926791 0.573205482926791 0.514300775319626 0.573205482926791
Smg5 ENSMUSG00000001415 0.0958690133561599 0.28760704006848 0.643853282854191 0.709375484777034 0.709375484777034 0.709375484777034
Gtf2h4 ENSMUSG00000001524 0.254787123615605 0.764361370846816 0.7802108304765 0.782117202022501 0.782117202022501 0.782117202022501
Puf60 ENSMUSG00000002524 0.338976281569376 0.508464422354065 0.781170242226513 0.781170242226513 0.141500034183268 0.424500102549803
Gtf2f1 ENSMUSG00000002658 0.395196379647461 0.592794569471191 0.0231500557096833 0.06945016712905 0.7802108304765 0.7802108304765
Psmd4 ENSMUSG00000005625 0.450094379653806 0.45596561163947 0.45596561163947 0.45596561163947 0.177153312234059 0.45596561163947
Psmb4 ENSMUSG00000005779 0.853049270252403 0.853049270252403 0.338976281569376 0.853049270252403 0.852940894477647 0.853049270252403
Rps9 ENSMUSG00000006333 0.347639524025037 0.926550375688041 0.643853282854191 0.926550375688041 0.926550375688041 0.926550375688041
Psmd2 ENSMUSG00000006998 0.852832278580641 0.852832278580641 0.643359829732651 0.852832278580641 0.711034989117171 0.852832278580641
Ppp2r1a ENSMUSG00000007564 0.345037391052887 0.51755608657933 0.778911768167544 0.778911768167544 0.252545530864481 0.51755608657933
Snrpb2 ENSMUSG00000008333 0.0171027900598199 0.0513083701794597 0.505838378028518 0.505838378028518 0.058823267388015 0.0882349010820225
Zmat5 ENSMUSG00000009076 0.572616808177226 0.576973746230334 0.576973746230334 0.576973746230334 0.400265374208515 0.576973746230334
Apobec3 ENSMUSG00000009585 0.249907451332337 0.399548817627028 0.399548817627028 0.399548817627028 0.297848640636702 0.399548817627028
Exosc10 ENSMUSG00000017264 0.640355507848752 0.777255087907932 0.777255087907932 0.777255087907932 0.638310022345193 0.777255087907932
Xab2 ENSMUSG00000019470 0.290984282074805 0.576973746230334 0.576973746230334 0.576973746230334 0.572616808177226 0.576973746230334
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Slu7 ENSMUSG00000020409 0.297848640636702 0.397384062266614 0.397384062266614 0.397384062266614 0.299349060054896 0.397384062266614
Cnot8 ENSMUSG00000020515 0.850151080737202 0.850151080737202 0.446194239410717 0.669291359116075 0.211110344399808 0.633331033199424
Nup85 ENSMUSG00000020739 0.454600801949285 0.683438032073173 0.455625354715448 0.683438032073173 0.852832278580641 0.852832278580641
Psmb5 ENSMUSG00000022193 0.702439833942814 0.702439833942814 0.343537039781257 0.67143283675232 0.447621891168214 0.67143283675232
Zcrb1 ENSMUSG00000022635 0.179945789077372 0.211844580334808 0.211844580334808 0.211844580334808 0.146800541856249 0.211844580334808
Ppil1 ENSMUSG00000024007 0.514934023620345 0.514934023620345 0.453570536021945 0.514934023620345 0.398108175780842 0.514934023620345
Wdr46 ENSMUSG00000024312 0.0953125666339395 0.285937699901819 0.846213121849299 0.846213121849299 0.699013321542257 0.846213121849299
Dhx16 ENSMUSG00000024422 0.146800541856249 0.440401625568746 0.850721744111585 0.924872384323463 0.924872384323463 0.924872384323463
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Rplp2 ENSMUSG00000025508 0.146800541856249 0.440401625568746 0.297848640636702 0.446772960955053 0.709375484777034 0.709375484777034
Eif4a3 ENSMUSG00000025580 0.454600801949285 0.681901202923927 0.710208797518812 0.710208797518812 0.449391287230099 0.681901202923927
Rqcd1 ENSMUSG00000026174 1 1 0.853907737111068 1 0.454942951775341 1
Snrpb ENSMUSG00000027404 0.643853282854191 0.643853282854191 0.5155648232968 0.643853282854191 0.180293335960318 0.540880007880955
Cstf1 ENSMUSG00000027498 0.850835096447629 0.850835096447629 0.572911448356892 0.850835096447629 0.511097249598474 0.850835096447629
Nol9 ENSMUSG00000028948 0.0101222094973346 0.0303666284920038 0.25141795904251 0.25141795904251 0.171859370212435 0.25141795904251
Snrnp35 ENSMUSG00000029402 0.058823267388015 0.176469802164045 0.200650219614881 0.300975329422321 0.77858338846904 0.77858338846904
Psmd9 ENSMUSG00000029440 0.78148726569172 0.926333123228344 0.643359829732651 0.926333123228344 0.926333123228344 0.926333123228344
Isy1 ENSMUSG00000030056 0.853801250889739 0.926658283600152 0.34837756124189 0.926658283600152 0.926658283600152 0.926658283600152
Rpl28 ENSMUSG00000030432 0.398108175780842 0.78148726569172 0.57466664340579 0.78148726569172 0.78148726569172 0.78148726569172
Psmc4 ENSMUSG00000030603 0.252920381501207 0.676192245442677 1 1 0.450794830295118 0.676192245442677
Polr2c ENSMUSG00000031783 0.638824656785692 0.638824656785692 0.452880492349546 0.638824656785692 0.29252580908486 0.638824656785692
Mphosph6 ENSMUSG00000031843 0.399548817627028 0.853480389728993 0.782117202022501 0.853480389728993 0.853480389728993 0.853480389728993
Pwp2 ENSMUSG00000032834 0.171503747555202 0.451840588205062 0.451840588205062 0.451840588205062 0.386972299618399 0.451840588205062
Polr2f ENSMUSG00000033020 0.637274134311157 0.637274134311157 0.299349060054896 0.637274134311157 0.575536202757516 0.637274134311157
Noc4l ENSMUSG00000033294 0.0331400397096515 0.0823468800653331 0.0548979200435554 0.0823468800653331 0.147458757705094 0.147458757705094
Cpsf1 ENSMUSG00000034022 0.213307944885796 0.639923834657388 1 1 1 1
Wdr18 ENSMUSG00000035754 0.505169133438821 0.505169133438821 0.254787123615605 0.382180685423408 0.211844580334808 0.382180685423408
Polr2l ENSMUSG00000038489 0.772410589885492 0.772410589885492 0.0701431284016185 0.210429385204856 0.50716883916608 0.760753258749121
Edc3 ENSMUSG00000038957 0.711034989117171 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Skiv2l ENSMUSG00000040356 0.641867098978198 0.711034989117171 0.711034989117171 0.711034989117171 0.513026869856283 0.711034989117171
Tbl3 ENSMUSG00000040688 0.508488713161374 0.852504981253341 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341
Cpsf2 ENSMUSG00000041781 0.00463747559282087 0.0139124267784626 0.0116356061791785 0.0174534092687678 1 1
Poldip3 ENSMUSG00000041815 0.575536202757516 0.863304304136274 0.926333123228344 0.926333123228344 0.452880492349546 0.863304304136274
Rps2 ENSMUSG00000044533 0.140165358447409 0.220200812784373 0.146800541856249 0.220200812784373 0.779238691542963 0.779238691542963
Gemin7 ENSMUSG00000044709 0.342405296020881 0.513607944031322 0.925217182211634 0.925217182211634 0.119631084167592 0.358893252502775
Zfp473 ENSMUSG00000048012 0.179945789077372 0.539837367232116 0.514934023620345 0.772401035430517 0.926658283600152 0.926658283600152
Lsm10 ENSMUSG00000050188 0.297848640636702 0.338592117141989 0.214764523938594 0.338592117141989 0.338592117141989 0.338592117141989
Nup188 ENSMUSG00000052533 0.214037080764326 0.252545530864481 0.179249687218049 0.252545530864481 0.252545530864481 0.252545530864481
Dnajc8 ENSMUSG00000054405 0.0897372356882884 0.269211707064865 0.335495677308116 0.449391287230099 0.449391287230099 0.449391287230099
Exosc5 ENSMUSG00000061286 0.0579478375430679 0.173843512629204 0.9255572759333 0.9255572759333 0.705968934865368 0.9255572759333
Phf5a ENSMUSG00000061360 0.852940894477647 0.852940894477647 0.706616781330066 0.852940894477647 0.57466664340579 0.852940894477647
U2af1 ENSMUSG00000061613 0.513665062682276 0.770497594023414 0.92622377157404 0.92622377157404 0.395928178642446 0.770497594023414
Gspt1 ENSMUSG00000062203 0.0325051220296005 0.0975153660888015 0.926658283600152 1 1 1
Sf3b5 ENSMUSG00000078348 0.925669613555092 0.925669613555092 0.0761127945805735 0.228338383741721 0.7802108304765 0.925669613555092
Rps13 ENSMUSG00000090862 0.577829325134931 0.577829325134931 0.514934023620345 0.577829325134931 0.120850531362929 0.362551594088788

The citric acid (TCA) cycle and respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cox5a ENSMUSG00000000088 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Atp5d ENSMUSG00000003072 0.0964252305385472 0.289275691615642 0.926003599371282 0.926003599371282 0.852504981253341 0.926003599371282
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Atp5g1 ENSMUSG00000006057 0.776919261684345 0.776919261684345 0.497625221907634 0.763717084845103 0.509144723230069 0.763717084845103
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Atp5e ENSMUSG00000016252 0.200650219614881 0.569937449249116 0.441845139428191 0.569937449249116 0.569937449249116 0.569937449249116
Atp5g3 ENSMUSG00000018770 0.441845139428191 0.779888212132595 0.779888212132595 0.779888212132595 0.635703516568382 0.779888212132595
Mdh2 ENSMUSG00000019179 0.708534948098331 0.708745765211584 0.447621891168214 0.708745765211584 0.708745765211584 0.708745765211584
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Cox11 ENSMUSG00000020544 0.57466664340579 0.78180291566155 0.78180291566155 0.78180291566155 0.300095920620218 0.78180291566155
Aco2 ENSMUSG00000022477 0.33116978622016 0.49675467933024 0.578113371816017 0.578113371816017 0.168646652367079 0.49675467933024
Cyc1 ENSMUSG00000022551 0.344663224299303 0.711240436189781 0.711240436189781 0.711240436189781 0.511097249598474 0.711240436189781
Bsg ENSMUSG00000023175 0.450794830295118 0.676192245442677 0.711650020253571 0.711650020253571 0.11993617140438 0.359808514213139
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Cox4i1 ENSMUSG00000031818 0.113498953177704 0.340496859533111 0.294820734456233 0.442231101684349 0.778253541606068 0.778253541606068
Slc16a1 ENSMUSG00000032902 0.514300775319626 0.771451162979439 0.782117202022501 0.782117202022501 0.216214347033995 0.648643041101984
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
Uqcrfs1 ENSMUSG00000038462 0.577829325134931 0.867170057724026 0.578113371816017 0.867170057724026 1 1
Coq10a ENSMUSG00000039914 0.0443599545252852 0.133079863575856 0.711854160331342 0.711854160331342 0.711240436189781 0.711854160331342
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

Complex I biogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ndufs3 ENSMUSG00000005510 0.438516479093275 0.955911201466735 1 1 0.637274134311157 0.955911201466735
Ndufs2 ENSMUSG00000013593 0.851954599472143 0.852504981253341 0.852504981253341 0.852504981253341 0.639337105615664 0.852504981253341
Ndufs7 ENSMUSG00000020153 0.286303237509397 0.575536202757516 0.575536202757516 0.575536202757516 0.395928178642446 0.575536202757516
Ndufb8 ENSMUSG00000025204 0.17924968721805 0.522013263352776 0.9255572759333 0.9255572759333 0.348008842235184 0.522013263352776
Ndufa8 ENSMUSG00000026895 0.709375484777034 0.709375484777034 0.17750354896016 0.53251064688048 0.397384062266614 0.596076093399921
Ndufs5 ENSMUSG00000028648 0.300095920620218 0.684457862089655 0.456305241393103 0.684457862089655 0.710416009055326 0.710416009055326
Ndufab1 ENSMUSG00000030869 0.180293335960318 0.270440003940477 0.0953125666339397 0.270440003940477 0.348008842235184 0.348008842235184
Ndufb7 ENSMUSG00000033938 0.641867098978198 0.779888212132595 0.211110344399808 0.633331033199424 0.779888212132595 0.779888212132595
Ndufv1 ENSMUSG00000037916 0.777922216623952 0.777922216623952 0.287873078401389 0.777922216623952 0.640861491578951 0.777922216623952
mt-Nd5 ENSMUSG00000064367 0.638310022345193 0.852065168704833 0.852065168704833 0.852065168704833 0.179945789077372 0.539837367232115
Ndufaf3 ENSMUSG00000070283 0.501782052576058 0.752673078864087 0.0741204440774082 0.222361332232225 1 1
Ndufb6 ENSMUSG00000071014 0.642366752097095 0.642366752097095 0.503822527122732 0.642366752097095 0.640355507848752 0.642366752097095

DNA Repair

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.254787123615605 0.764361370846816 0.7802108304765 0.782117202022501 0.782117202022501 0.782117202022501
Top3a ENSMUSG00000002814 0.398469281729516 0.926604389137101 0.926604389137101 0.926604389137101 0.643112334413352 0.926604389137101
Actr8 ENSMUSG00000015971 0.853372965654504 1 1 1 0.45596561163947 1
Hist1h2bc ENSMUSG00000018102 0.453225835454266 0.780851835278817 0.780851835278817 0.780851835278817 0.643359829732651 0.780851835278817
Xab2 ENSMUSG00000019470 0.290984282074805 0.576973746230334 0.576973746230334 0.576973746230334 0.572616808177226 0.576973746230334
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Kdm4b ENSMUSG00000024201 0.0241933715424143 0.0725801146272428 1 1 1 1
Ddb1 ENSMUSG00000024740 0.509144723230069 0.763717084845103 0.92622377157404 0.92622377157404 0.295581119060361 0.763717084845103
Poll ENSMUSG00000025218 0.178901132102685 0.383851786434905 0.511742979522636 0.511742979522636 0.255901190956604 0.383851786434905
Atrip ENSMUSG00000025646 1 1 0.78180291566155 1 0.643853282854191 1
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Dclre1c ENSMUSG00000026648 0.249907451332337 0.255901190956604 0.255901190956604 0.255901190956604 0.178901132102685 0.255901190956604
Chd1l ENSMUSG00000028089 0.781170242226513 0.853372965654504 0.852065168704833 0.853372965654504 0.853372965654504 0.853372965654504
Usp1 ENSMUSG00000028560 0.569937449249116 0.569937449249116 0.00037335518005407 0.00112006554016221 0.0753654386865988 0.113048158029898
Pole4 ENSMUSG00000030042 0.711650020253571 0.926333123228344 0.641867098978198 0.926333123228344 0.926333123228344 0.926333123228344
Isy1 ENSMUSG00000030056 0.853801250889739 0.926658283600152 0.34837756124189 0.926658283600152 0.926658283600152 0.926658283600152
Ppp4c ENSMUSG00000030697 0.345410946355104 0.926441990075769 0.853801250889739 0.926441990075769 0.926441990075769 0.926441990075769
Brcc3 ENSMUSG00000031201 0.17750354896016 0.26625532344024 1 1 0.144820068500793 0.26625532344024
Polr2c ENSMUSG00000031783 0.638824656785692 0.638824656785692 0.452880492349546 0.638824656785692 0.29252580908486 0.638824656785692
Usp10 ENSMUSG00000031826 0.179945789077372 0.539837367232116 0.711240436189781 0.712057867818062 0.712057867818062 0.712057867818062
Neil1 ENSMUSG00000032298 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.119631084167592 0.358893252502775
Polr2f ENSMUSG00000033020 0.637274134311157 0.637274134311157 0.299349060054896 0.637274134311157 0.575536202757516 0.637274134311157
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Sirt6 ENSMUSG00000034748 0.297848640636702 0.577259514257969 0.455625354715449 0.577259514257969 0.577259514257969 0.577259514257969
Fam175a ENSMUSG00000035234 0.509144723230069 0.926658283600152 0.711854160331342 0.926658283600152 0.926658283600152 0.926658283600152
Mcrs1 ENSMUSG00000037570 0.162867964743396 0.488603894230187 0.711650020253571 0.711650020253571 0.706831781264721 0.711650020253571
Acd ENSMUSG00000038000 0.513665062682276 1 0.78148726569172 1 1 1
Polr2l ENSMUSG00000038489 0.772410589885492 0.772410589885492 0.0701431284016185 0.210429385204856 0.50716883916608 0.760753258749121
2810417H13Rik ENSMUSG00000040204 0.148772260628989 0.223158390943484 0.0441715176243983 0.132514552873195 0.513665062682276 0.513665062682276
H2afv ENSMUSG00000041126 0.348377561241889 0.852175490580835 0.706831781264722 0.852175490580835 0.852175490580835 0.852175490580835
Adprhl2 ENSMUSG00000042558 0.179249687218049 0.537749061654148 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Hist3h2ba ENSMUSG00000056895 0.926333123228344 0.926333123228344 0.643359829732651 0.926333123228344 0.710001140920767 0.926333123228344
H2afj ENSMUSG00000060032 0.0953125666339397 0.285937699901819 0.250285839267991 0.375428758901986 0.576112968612194 0.576112968612194
Hist1h4i ENSMUSG00000060639 0.29252580908486 0.776919261684345 0.776919261684345 0.776919261684345 0.711034989117171 0.776919261684345
Hist1h4h ENSMUSG00000060981 0.78148726569172 1 1 1 0.5155648232968 1
2610002J02Rik ENSMUSG00000073684 0.142165951159432 0.395196379647461 0.29252580908486 0.395196379647461 0.395196379647461 0.395196379647461
Hist1h2bb ENSMUSG00000075031 0.702215027772976 0.775560609711725 0.775560609711725 0.775560609711725 0.363631147570911 0.775560609711725
RNF8 ENSMUSG00000098374 0.345410946355104 0.518116419532656 0.0583853430099098 0.175156029029729 0.639337105615664 0.639337105615664

Macroautophagy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atg4d ENSMUSG00000002820 0.171859370212435 0.515578110637305 0.576973746230334 0.639337105615664 0.639337105615664 0.639337105615664
Tomm40 ENSMUSG00000002984 0.148115998140416 0.444347994421247 0.775217051297351 0.775217051297351 0.503822527122732 0.755733790684098
Pex5 ENSMUSG00000005069 0.924872384323463 1 1 1 0.77858338846904 1
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Wdr45b ENSMUSG00000025173 0.853480389728993 0.853480389728993 0.643853282854191 0.853480389728993 0.711034989117171 0.853480389728993
Map1lc3a ENSMUSG00000027602 0.148115998140416 0.398108175780842 0.398108175780842 0.398108175780842 0.299349060054895 0.398108175780842
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Pgam5 ENSMUSG00000029500 0.710001140920767 0.780851835278818 0.454600801949285 0.780851835278818 0.780851835278818 0.780851835278818
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Mtmr14 ENSMUSG00000030269 1 1 0.21549027811633 0.64647083434899 0.926003599371282 1
Lamtor1 ENSMUSG00000030842 0.179249687218049 0.537749061654148 0.924987846321933 0.924987846321933 0.77858338846904 0.924987846321933
Map1lc3b ENSMUSG00000031812 0.242231702094921 0.432981635415313 0.636229315311352 0.636229315311352 0.288654423610209 0.432981635415313
Gabarapl2 ENSMUSG00000031950 0.852940894477647 0.853480389728993 0.451840588205062 0.853480389728993 0.853480389728993 0.853480389728993
Chmp7 ENSMUSG00000034190 0.399548817627028 0.577259514257969 0.577259514257969 0.577259514257969 0.180293335960318 0.540880007880955
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Prkag1 ENSMUSG00000067713 0.342026805366747 0.51304020805012 1 1 0.254414773803597 0.51304020805012

Autophagy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Atg4d ENSMUSG00000002820 0.171859370212435 0.515578110637305 0.576973746230334 0.639337105615664 0.639337105615664 0.639337105615664
Tomm40 ENSMUSG00000002984 0.148115998140416 0.444347994421247 0.775217051297351 0.775217051297351 0.503822527122732 0.755733790684098
Pex5 ENSMUSG00000005069 0.924872384323463 1 1 1 0.77858338846904 1
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Park2 ENSMUSG00000023826 0.252920381501207 0.75876114450362 0.710001140920767 0.926550375688041 0.926550375688041 0.926550375688041
Wdr45b ENSMUSG00000025173 0.853480389728993 0.853480389728993 0.643853282854191 0.853480389728993 0.711034989117171 0.853480389728993
Map1lc3a ENSMUSG00000027602 0.148115998140416 0.398108175780842 0.398108175780842 0.398108175780842 0.299349060054895 0.398108175780842
Park7 ENSMUSG00000028964 0.299349060054895 0.770497594023414 0.513665062682276 0.770497594023414 1 1
Pgam5 ENSMUSG00000029500 0.710001140920767 0.780851835278818 0.454600801949285 0.780851835278818 0.780851835278818 0.780851835278818
Wipi2 ENSMUSG00000029578 0.572616808177226 0.572616808177226 0.295581119060361 0.443371678590541 0.118409250205154 0.355227750615461
Mtmr14 ENSMUSG00000030269 1 1 0.21549027811633 0.64647083434899 0.926003599371282 1
Lamtor1 ENSMUSG00000030842 0.179249687218049 0.537749061654148 0.924987846321933 0.924987846321933 0.77858338846904 0.924987846321933
Map1lc3b ENSMUSG00000031812 0.242231702094921 0.432981635415313 0.636229315311352 0.636229315311352 0.288654423610209 0.432981635415313
Gabarapl2 ENSMUSG00000031950 0.852940894477647 0.853480389728993 0.451840588205062 0.853480389728993 0.853480389728993 0.853480389728993
Chmp7 ENSMUSG00000034190 0.399548817627028 0.577259514257969 0.577259514257969 0.577259514257969 0.180293335960318 0.540880007880955
Becn1 ENSMUSG00000035086 0.505838378028518 0.573205482926791 0.141500034183268 0.424500102549803 0.573205482926791 0.573205482926791
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Prkag1 ENSMUSG00000067713 0.342026805366747 0.51304020805012 1 1 0.254414773803597 0.51304020805012

Membrane Trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Snapin ENSMUSG00000001018 0.577259514257969 0.643359829732651 0.389247465657472 0.643359829732651 0.643359829732651 0.643359829732651
Trappc6a ENSMUSG00000002043 0.18064054691103 0.522013263352776 0.711854160331342 0.711854160331342 0.348008842235184 0.522013263352776
Ykt6 ENSMUSG00000002741 0.453225835454266 0.679838753181399 0.781170242226513 0.781170242226513 0.400265374208515 0.679838753181399
Kdelr1 ENSMUSG00000002778 0.252545530864481 0.378818296296722 0.705968934865368 0.705968934865368 0.177853449259986 0.378818296296722
Ap2s1 ENSMUSG00000008036 0.281535759592779 0.33116978622016 0.0869438727002335 0.2608316181007 0.33116978622016 0.33116978622016
Ap1b1 ENSMUSG00000009090 0.213307944885796 0.319961917328694 0.499716455239609 0.499716455239609 0.0579478375430677 0.173843512629203
Tmem115 ENSMUSG00000010045 0.397384062266614 0.596076093399921 0.708745765211584 0.708745765211584 0.283134662157423 0.596076093399921
Surf4 ENSMUSG00000014867 0.851061028660105 1 1 1 0.250285839267991 0.750857517803972
Cyth1 ENSMUSG00000017132 0.345410946355104 0.573498913947369 0.573498913947369 0.573498913947369 0.447265995733381 0.573498913947369
Copz2 ENSMUSG00000018672 0.146800541856249 0.220200812784373 0.0763619660358786 0.220200812784373 0.643359829732651 0.643359829732651
Arrb1 ENSMUSG00000018909 0.295581119060361 0.443371678590541 0.640861491578951 0.640861491578951 0.146800541856249 0.440401625568746
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Apob ENSMUSG00000020609 0.853372965654504 0.853372965654504 0.0577292451600846 0.173187735480254 0.577829325134931 0.853372965654504
Gosr2 ENSMUSG00000020946 1 1 0.450444934184774 0.675667401277161 0.180293335960318 0.540880007880955
Tbc1d7 ENSMUSG00000021368 0.211844580334808 0.317766870502212 0.0441715176243983 0.132514552873195 0.395928178642446 0.395928178642446
Bnip1 ENSMUSG00000024191 0.0766111619812296 0.229833485943689 0.397384062266614 0.596076093399921 0.852504981253341 0.852504981253341
Vps51 ENSMUSG00000024797 0.25141795904251 0.443371678590541 0.782117202022501 0.782117202022501 0.295581119060361 0.443371678590541
Csnk1d ENSMUSG00000025162 0.453225835454266 0.679838753181399 0.77858338846904 0.77858338846904 0.346527959006435 0.679838753181399
Actr1a ENSMUSG00000025228 0.342026805366747 0.51304020805012 0.84992097596507 0.84992097596507 0.213307944885796 0.51304020805012
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Arfgap2 ENSMUSG00000027255 0.454600801949285 0.863304304136274 0.925444427431699 0.925444427431699 0.575536202757516 0.863304304136274
Tbc1d20 ENSMUSG00000027465 0.0936419271039908 0.280925781311972 0.450444934184774 0.675667401277161 0.852065168704833 0.852065168704833
Dctn3 ENSMUSG00000028447 0.926550375688041 0.926550375688041 0.392243127063687 0.926550375688041 0.640355507848752 0.926550375688041
Trappc3 ENSMUSG00000028847 0.117185073436597 0.351555220309791 0.446194239410717 0.669291359116075 1 1
Necap2 ENSMUSG00000028923 0.34837756124189 0.641867098978198 0.641867098978198 0.641867098978198 0.5155648232968 0.641867098978198
Arpc1a ENSMUSG00000029621 0.214037080764326 0.450143880930327 0.300095920620218 0.450143880930327 0.853372965654504 0.853372965654504
Copg1 ENSMUSG00000030058 0.395928178642446 0.395928178642446 0.395928178642446 0.395928178642446 0.118714930081337 0.35614479024401
Ctsc ENSMUSG00000030560 0.0334587898203823 0.100376369461147 0.643853282854191 0.643853282854191 0.346899083932133 0.520348625898199
F8 ENSMUSG00000031196 0.397384062266614 0.596076093399921 0.853801250889739 0.853801250889739 0.0733738589968007 0.220121576990402
Map1lc3b ENSMUSG00000031812 0.242231702094921 0.432981635415313 0.636229315311352 0.636229315311352 0.288654423610209 0.432981635415313
Mvb12a ENSMUSG00000031813 0.514934023620345 0.643359829732651 0.643359829732651 0.643359829732651 0.578396848531894 0.643359829732651
Vps4a ENSMUSG00000031913 0.573498913947369 0.573498913947369 0.505169133438821 0.573498913947369 0.17924968721805 0.537749061654149
Gabarapl2 ENSMUSG00000031950 0.852940894477647 0.853480389728993 0.451840588205062 0.853480389728993 0.853480389728993 0.853480389728993
Trappc4 ENSMUSG00000032112 0.853801250889739 0.853801250889739 0.300095920620218 0.450143880930327 0.256271555563966 0.450143880930327
Tmed3 ENSMUSG00000032353 0.454600801949285 0.454600801949285 0.000701972248021392 0.00210591674406418 0.0947558980989551 0.142133847148433
Gorasp1 ENSMUSG00000032513 0.345037391052887 0.50716883916608 0.50716883916608 0.50716883916608 0.177153312234059 0.50716883916608
Chmp7 ENSMUSG00000034190 0.399548817627028 0.577259514257969 0.577259514257969 0.577259514257969 0.180293335960318 0.540880007880955
Golgb1 ENSMUSG00000034243 0.297848640636702 0.710416009055326 0.710416009055326 0.710416009055326 0.576973746230334 0.710416009055326
Tbc1d10a ENSMUSG00000034412 0.853372965654504 0.853372965654504 0.78148726569172 0.853372965654504 0.781170242226513 0.853372965654504
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Sbf1 ENSMUSG00000036529 0.21549027811633 0.438788713627291 0.452880492349546 0.452880492349546 0.29252580908486 0.438788713627291
Trappc11 ENSMUSG00000038102 0.643853282854191 0.853801250889739 0.398829756175299 0.853801250889739 0.853801250889739 0.853801250889739
Sec24c ENSMUSG00000039367 0.575536202757516 0.863304304136274 0.924639851733043 0.924639851733043 0.246861959455465 0.740585878366394
Tubb2b ENSMUSG00000045136 0.0964252305385472 0.289275691615642 0.513665062682276 0.513665062682276 0.453225835454266 0.513665062682276
Preb ENSMUSG00000045302 0.148115998140416 0.444347994421247 0.926550375688041 1 1 1
Sys1 ENSMUSG00000045503 0.348008842235184 0.772401035430517 0.926550375688041 0.926550375688041 0.514934023620345 0.772401035430517
Arf1 ENSMUSG00000048076 0.777255087907932 0.77858338846904 0.77858338846904 0.77858338846904 0.297848640636702 0.77858338846904
Cope ENSMUSG00000055681 0.925444427431699 0.925444427431699 0.453570536021945 0.864169452918291 0.576112968612194 0.864169452918291
Bloc1s3 ENSMUSG00000057667 0.92589277149125 0.92589277149125 0.852175490580835 0.92589277149125 0.577259514257969 0.92589277149125
Sptan1 ENSMUSG00000057738 0.508488713161374 0.78180291566155 0.779238691542963 0.78180291566155 0.78180291566155 0.78180291566155
Tmed9 ENSMUSG00000058569 0.454600801949285 0.681901202923927 0.392243127063687 0.681901202923927 0.711034989117171 0.711034989117171
Tubb2a ENSMUSG00000058672 0.852504981253341 0.852504981253341 0.513665062682276 0.770497594023414 0.346899083932133 0.770497594023414
Copz1 ENSMUSG00000060992 0.294820734456232 0.7802108304765 0.643853282854191 0.7802108304765 0.7802108304765 0.7802108304765
Actg1 ENSMUSG00000062825 0.214037080764326 0.321055621146488 0.327972855903273 0.327972855903273 0.211110344399808 0.321055621146488
Rabepk ENSMUSG00000070953 0.180293335960318 0.270440003940477 0.348008842235184 0.348008842235184 0.0964252305385472 0.270440003940477
Kdelr2 ENSMUSG00000079111 0.514300775319626 0.771451162979439 0.0575107614292586 0.172532284287776 1 1

Formation of TC-NER Pre-Incision Complex

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gtf2h4 ENSMUSG00000001524 0.254787123615605 0.764361370846816 0.7802108304765 0.782117202022501 0.782117202022501 0.782117202022501
Xab2 ENSMUSG00000019470 0.290984282074805 0.576973746230334 0.576973746230334 0.576973746230334 0.572616808177226 0.576973746230334
Cops6 ENSMUSG00000019494 0.638051880670243 0.638051880670243 0.0323469380768478 0.0970408142305435 0.341267950445512 0.511901925668268
Ubb ENSMUSG00000019505 0.925444427431699 0.925444427431699 0.11810342389482 0.354310271684459 0.393724994268831 0.590587491403246
Ddb1 ENSMUSG00000024740 0.509144723230069 0.763717084845103 0.92622377157404 0.92622377157404 0.295581119060361 0.763717084845103
Cops7b ENSMUSG00000026240 0.701310685803632 0.701310685803632 0.566593564630738 0.701310685803632 0.447265995733381 0.701310685803632
Isy1 ENSMUSG00000030056 0.853801250889739 0.926658283600152 0.34837756124189 0.926658283600152 0.926658283600152 0.926658283600152
Polr2c ENSMUSG00000031783 0.638824656785692 0.638824656785692 0.452880492349546 0.638824656785692 0.29252580908486 0.638824656785692
Polr2f ENSMUSG00000033020 0.637274134311157 0.637274134311157 0.299349060054896 0.637274134311157 0.575536202757516 0.637274134311157
Cops8 ENSMUSG00000034432 0.924872384323463 0.924872384323463 0.288654423610209 0.443371678590541 0.295581119060361 0.443371678590541
Polr2l ENSMUSG00000038489 0.772410589885492 0.772410589885492 0.0701431284016185 0.210429385204856 0.50716883916608 0.760753258749121

darkolivegreen4

Herpes simplex virus 1 infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Zfp81 ENSMUSG00000003929 0.299349060054895 0.449023590082343 0.453225835454266 0.453225835454266 0.148115998140416 0.444347994421247
Zfp715 ENSMUSG00000012640 0.0231500557096833 0.0694501671290499 0.852940894477647 0.852940894477647 0.711034989117171 0.852940894477647
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
2810021J22Rik ENSMUSG00000020491 0.578113371816017 0.867170057724026 0.299349060054895 0.867170057724026 0.926658283600152 0.926658283600152
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Jak2 ENSMUSG00000024789 0.214764523938594 0.322146785907891 0.0334587898203823 0.100376369461147 0.514300775319626 0.514300775319626
Zfp12 ENSMUSG00000029587 0.00442026986621115 0.0132608095986334 0.711034989117171 0.711034989117171 0.297848640636702 0.446772960955053
Zik1 ENSMUSG00000030393 0.300095920620218 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Zfp273 ENSMUSG00000030446 0.710001140920767 0.926333123228344 0.514934023620344 0.926333123228344 0.926333123228344 0.926333123228344
Zfp944 ENSMUSG00000033972 0.147458757705094 0.442376273115283 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Zfp57 ENSMUSG00000036036 0.21549027811633 0.323235417174495 0.576112968612194 0.576112968612194 0.0113089139751576 0.0339267419254727
Zfp157 ENSMUSG00000036898 0.255901190956604 0.511331374485819 0.340887582990546 0.511331374485819 0.643853282854191 0.643853282854191
Zfp60 ENSMUSG00000037640 0.346527959006435 1 1 1 0.853801250889739 1
Zfp286 ENSMUSG00000047342 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Zfp952 ENSMUSG00000053390 0.253294730253594 0.683948417459205 0.45596561163947 0.683948417459205 0.926550375688041 0.926550375688041
Zfp182 ENSMUSG00000054737 0.578113371816017 0.578113371816017 0.297848640636702 0.446772960955053 0.255530331334266 0.446772960955053
Zfp811 ENSMUSG00000055202 0.0741204440774081 0.222361332232224 0.575536202757516 0.575536202757516 0.514934023620345 0.575536202757516
Zfp1 ENSMUSG00000055835 0.514934023620344 0.578113371816017 0.0753654386865988 0.226096316059796 0.578113371816017 0.578113371816017
AI987944 ENSMUSG00000056383 0.92622377157404 0.92622377157404 0.346899083932133 0.522566341862834 0.348377561241889 0.522566341862834
Zfp658 ENSMUSG00000056592 0.11993617140438 0.214246374477256 0.142830916318171 0.214246374477256 0.643359829732651 0.643359829732651
Zfp317 ENSMUSG00000057551 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Zfp68 ENSMUSG00000058291 0.0753654386865987 0.226096316059796 0.399548817627028 0.599323226440542 0.643359829732651 0.643359829732651
Zfp420 ENSMUSG00000058402 0.297848640636702 0.772401035430517 0.514934023620345 0.772401035430517 0.853801250889739 0.853801250889739
Zfp933 ENSMUSG00000059423 0.180293335960318 0.449023590082343 0.779888212132595 0.779888212132595 0.299349060054895 0.449023590082343
2610008E11Rik ENSMUSG00000060301 0.711854160331342 0.711854160331342 0.180293335960318 0.540880007880955 0.578396848531894 0.711854160331342
Zfp266 ENSMUSG00000060510 0.180293335960318 0.443669460449296 0.443669460449296 0.443669460449296 0.297095062262363 0.443669460449296
Rbak ENSMUSG00000061898 0.148115998140416 0.379942095380391 0.253294730253594 0.379942095380391 0.576112968612194 0.576112968612194
Zfp26 ENSMUSG00000063108 0.642366752097095 0.642366752097095 0.254414773803597 0.642366752097095 0.514300775319626 0.642366752097095
Zfp810 ENSMUSG00000066829 0.455625354715449 0.577829325134931 0.577829325134931 0.577829325134931 0.399907408151082 0.577829325134931
Zfp617 ENSMUSG00000066880 0.0947558980989551 0.284267694296865 0.926550375688041 0.926550375688041 0.578396848531894 0.867595272797842
Zfp760 ENSMUSG00000067928 0.147458757705094 0.442376273115283 0.85117361048289 0.85117361048289 0.397384062266614 0.596076093399921
Zfp120 ENSMUSG00000068134 0.348377561241889 0.711034989117171 0.576973746230334 0.711034989117171 0.711034989117171 0.711034989117171
Zfp619 ENSMUSG00000068959 0.92622377157404 0.92622377157404 0.782117202022501 0.92622377157404 0.455625354715448 0.92622377157404
Gm5595 ENSMUSG00000069727 0.119936171404379 0.359808514213138 0.397384062266614 0.453570536021945 0.453570536021945 0.453570536021945
Zfp788 ENSMUSG00000074165 0.0763619660358789 0.229085898107637 0.926333123228344 0.926333123228344 0.642366752097095 0.926333123228344
Zfp808 ENSMUSG00000074867 1 1 0.51077343128446 1 0.853694531487825 1
E430018J23Rik ENSMUSG00000078580 0.11810342389482 0.354310271684459 0.852175490580835 0.852175490580835 0.514300775319626 0.771451162979439
Zfp141 ENSMUSG00000092416 0.513026869856283 0.769540304784424 0.399548817627028 0.769540304784424 0.78180291566155 0.78180291566155
Zfp799 ENSMUSG00000095253 0.348377561241889 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968
Zfp748 ENSMUSG00000095432 0.0441715176243982 0.132514552873195 0.578113371816017 0.578113371816017 0.343537039781257 0.515305559671886
Zfp97 ENSMUSG00000095990 0.643853282854191 0.926658283600152 0.926658283600152 0.926658283600152 0.853801250889739 0.926658283600152

RNA transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Xpo1 ENSMUSG00000020290 0.119631084167591 0.358893252502774 0.853372965654504 1 1 1
Cyfip2 ENSMUSG00000020340 0.853372965654504 0.853372965654504 0.711650020253571 0.853372965654504 0.642864324224729 0.853372965654504
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Rpp30 ENSMUSG00000024800 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739
Ddx20 ENSMUSG00000027905 0.0763619660358785 0.229085898107636 0.853694531487825 0.853694531487825 0.397384062266614 0.596076093399921
Tgs1 ENSMUSG00000028233 0.0241933715424143 0.0725801146272428 1 1 0.643853282854191 0.965779924281287
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nxt2 ENSMUSG00000042271 0.144820068500793 0.434460205502379 0.638310022345193 0.638310022345193 0.578396848531894 0.638310022345193
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Gene expression (Transcription)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tead3 ENSMUSG00000002249 0.926387617028817 0.926387617028817 0.781011212316137 0.926387617028817 0.577544706586058 0.926387617028817
Zfp81 ENSMUSG00000003929 0.299349060054895 0.449023590082343 0.453225835454266 0.453225835454266 0.148115998140416 0.444347994421247
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ywhah ENSMUSG00000018965 0.711650020253571 0.853694531487825 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Twistnb ENSMUSG00000020561 0.0969812105731562 0.290943631719469 0.400265374208515 0.600398061312773 0.643359829732651 0.643359829732651
Kat2a ENSMUSG00000020918 0.345037391052887 0.520348625898199 0.778911768167544 0.778911768167544 0.346899083932133 0.520348625898199
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Esrrb ENSMUSG00000021255 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nr1d2 ENSMUSG00000021775 0.0579478375430677 0.173843512629203 0.179945789077372 0.179945789077372 0.178901132102685 0.179945789077372
Med4 ENSMUSG00000022109 0.781170242226513 0.781170242226513 0.5155648232968 0.7733472349452 0.178901132102685 0.536703396308054
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Zfp263 ENSMUSG00000022529 0.642366752097095 0.642366752097095 0.298599969973533 0.522013263352776 0.348008842235184 0.522013263352776
Gtf2e1 ENSMUSG00000022828 0.146141353215796 0.438424059647387 0.926658283600152 1 1 1
Dpy30 ENSMUSG00000024067 0.10607024422363 0.31821073267089 0.334323804341914 0.334323804341914 0.283134662157423 0.334323804341914
Csnk2b ENSMUSG00000024387 0.514300775319626 0.925669613555092 0.7802108304765 0.925669613555092 0.925669613555092 0.925669613555092
Ccnt2 ENSMUSG00000026349 0.343537039781257 0.515305559671885 0.179249687218049 0.515305559671885 0.643359829732651 0.643359829732651
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
Polr3f ENSMUSG00000027427 0.0763619660358786 0.229085898107636 0.171859370212435 0.257789055318653 0.781170242226513 0.781170242226513
Trp53inp1 ENSMUSG00000028211 0.024062085667391 0.0721862570021729 0.577259514257969 0.853480389728993 0.853480389728993 0.853480389728993
Gtf2h3 ENSMUSG00000029387 0.926658283600152 0.926658283600152 0.147458757705094 0.442376273115283 0.578113371816017 0.867170057724026
Mapkapk5 ENSMUSG00000029454 0.853801250889739 0.853801250889739 0.148115998140415 0.444347994421246 0.399548817627028 0.599323226440542
Zfp12 ENSMUSG00000029587 0.00442026986621115 0.0132608095986334 0.711034989117171 0.711034989117171 0.297848640636702 0.446772960955053
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Zfp606 ENSMUSG00000030386 1 1 0.300095920620218 0.900287761860654 0.643853282854191 0.965779924281287
Zik1 ENSMUSG00000030393 0.300095920620218 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Gtf2e2 ENSMUSG00000031585 0.244170096021948 0.522013263352776 0.348008842235184 0.522013263352776 1 1
Cnot7 ENSMUSG00000031601 0.179945789077372 0.539837367232116 0.643359829732651 0.926550375688041 0.926550375688041 0.926550375688041
Mre11a ENSMUSG00000031928 0.926333123228344 0.926333123228344 0.642864324224729 0.926333123228344 0.216214347033995 0.648643041101984
Med17 ENSMUSG00000031935 0.18064054691103 0.54192164073309 0.643853282854191 0.643853282854191 0.57466664340579 0.643853282854191
Narg2 ENSMUSG00000032235 0.851732715229127 1 0.144820068500793 0.43446020550238 1 1
Zfp944 ENSMUSG00000033972 0.147458757705094 0.442376273115283 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Dna2 ENSMUSG00000036875 0.768937368234818 0.768937368234818 0.391871008462512 0.768937368234818 0.631140429608896 0.768937368234818
Zfp157 ENSMUSG00000036898 0.255901190956604 0.511331374485819 0.340887582990546 0.511331374485819 0.643853282854191 0.643853282854191
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Psme4 ENSMUSG00000040850 0.513665062682276 0.5155648232968 0.21549027811633 0.5155648232968 0.5155648232968 0.5155648232968
Zfp445 ENSMUSG00000047036 0.216214347033995 0.255901190956604 0.179249687218049 0.255901190956604 0.255901190956604 0.255901190956604
Zfp286 ENSMUSG00000047342 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Slc38a9 ENSMUSG00000047789 0.0969812105731562 0.290943631719469 1 1 0.399548817627028 0.599323226440542
Rictor ENSMUSG00000050310 0.120545895661628 0.361637686984883 0.642864324224729 0.711854160331342 0.711854160331342 0.711854160331342
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Zfp952 ENSMUSG00000053390 0.253294730253594 0.683948417459205 0.45596561163947 0.683948417459205 0.926550375688041 0.926550375688041
Skp2 ENSMUSG00000054115 0.0733738589968007 0.220121576990402 0.146800541856249 0.220200812784373 0.346899083932133 0.346899083932133
Zfp811 ENSMUSG00000055202 0.0741204440774081 0.222361332232224 0.575536202757516 0.575536202757516 0.514934023620345 0.575536202757516
AI987944 ENSMUSG00000056383 0.92622377157404 0.92622377157404 0.346899083932133 0.522566341862834 0.348377561241889 0.522566341862834
Zfp658 ENSMUSG00000056592 0.11993617140438 0.214246374477256 0.142830916318171 0.214246374477256 0.643359829732651 0.643359829732651
Zfp317 ENSMUSG00000057551 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Zfp420 ENSMUSG00000058402 0.297848640636702 0.772401035430517 0.514934023620345 0.772401035430517 0.853801250889739 0.853801250889739
Taf1b ENSMUSG00000059669 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501 0.643853282854191 0.782117202022501
Zkscan8 ENSMUSG00000063894 0.348008842235184 0.683948417459205 0.45596561163947 0.683948417459205 1 1
Zfp810 ENSMUSG00000066829 0.455625354715449 0.577829325134931 0.577829325134931 0.577829325134931 0.399907408151082 0.577829325134931
Zfp617 ENSMUSG00000066880 0.0947558980989551 0.284267694296865 0.926550375688041 0.926550375688041 0.578396848531894 0.867595272797842
Zfp760 ENSMUSG00000067928 0.147458757705094 0.442376273115283 0.85117361048289 0.85117361048289 0.397384062266614 0.596076093399921
Zfp120 ENSMUSG00000068134 0.348377561241889 0.711034989117171 0.576973746230334 0.711034989117171 0.711034989117171 0.711034989117171
Gm5595 ENSMUSG00000069727 0.119936171404379 0.359808514213138 0.397384062266614 0.453570536021945 0.453570536021945 0.453570536021945
Cited4 ENSMUSG00000070803 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.577829325134931 0.577829325134931
Gm4924 ENSMUSG00000073427 1 1 1 1 0.5155648232968 1
9830147E19Rik ENSMUSG00000074158 0.514934023620345 0.514934023620345 0.455625354715448 0.514934023620345 0.117185073436597 0.351555220309791
Etohi1 ENSMUSG00000074519 0.0241933715424143 0.0725801146272428 0.399189600887034 0.399189600887034 0.254414773803597 0.381622160705395
E430018J23Rik ENSMUSG00000078580 0.11810342389482 0.354310271684459 0.852175490580835 0.852175490580835 0.514300775319626 0.771451162979439
Smarcd2 ENSMUSG00000078619 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803 0.211844580334808 0.437634314982803
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651
Lamtor3 ENSMUSG00000091512 0.0441715176243983 0.132514552873195 0.451840588205062 0.451840588205062 0.0969812105731563 0.145471815859735
Zfp955a ENSMUSG00000094441 0.254414773803597 0.763244321410791 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Zfp799 ENSMUSG00000095253 0.348377561241889 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968
Zfp748 ENSMUSG00000095432 0.0441715176243982 0.132514552873195 0.578113371816017 0.578113371816017 0.343537039781257 0.515305559671886
Zfp97 ENSMUSG00000095990 0.643853282854191 0.926658283600152 0.926658283600152 0.926658283600152 0.853801250889739 0.926658283600152

RNA Polymerase II Transcription

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tead3 ENSMUSG00000002249 0.926387617028817 0.926387617028817 0.781011212316137 0.926387617028817 0.577544706586058 0.926387617028817
Zfp81 ENSMUSG00000003929 0.299349060054895 0.449023590082343 0.453225835454266 0.453225835454266 0.148115998140416 0.444347994421247
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ywhah ENSMUSG00000018965 0.711650020253571 0.853694531487825 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Kat2a ENSMUSG00000020918 0.345037391052887 0.520348625898199 0.778911768167544 0.778911768167544 0.346899083932133 0.520348625898199
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Esrrb ENSMUSG00000021255 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Nr1d2 ENSMUSG00000021775 0.0579478375430677 0.173843512629203 0.179945789077372 0.179945789077372 0.178901132102685 0.179945789077372
Med4 ENSMUSG00000022109 0.781170242226513 0.781170242226513 0.5155648232968 0.7733472349452 0.178901132102685 0.536703396308054
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Zfp263 ENSMUSG00000022529 0.642366752097095 0.642366752097095 0.298599969973533 0.522013263352776 0.348008842235184 0.522013263352776
Gtf2e1 ENSMUSG00000022828 0.146141353215796 0.438424059647387 0.926658283600152 1 1 1
Dpy30 ENSMUSG00000024067 0.10607024422363 0.31821073267089 0.334323804341914 0.334323804341914 0.283134662157423 0.334323804341914
Csnk2b ENSMUSG00000024387 0.514300775319626 0.925669613555092 0.7802108304765 0.925669613555092 0.925669613555092 0.925669613555092
Ccnt2 ENSMUSG00000026349 0.343537039781257 0.515305559671885 0.179249687218049 0.515305559671885 0.643359829732651 0.643359829732651
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
Trp53inp1 ENSMUSG00000028211 0.024062085667391 0.0721862570021729 0.577259514257969 0.853480389728993 0.853480389728993 0.853480389728993
Gtf2h3 ENSMUSG00000029387 0.926658283600152 0.926658283600152 0.147458757705094 0.442376273115283 0.578113371816017 0.867170057724026
Mapkapk5 ENSMUSG00000029454 0.853801250889739 0.853801250889739 0.148115998140415 0.444347994421246 0.399548817627028 0.599323226440542
Zfp12 ENSMUSG00000029587 0.00442026986621115 0.0132608095986334 0.711034989117171 0.711034989117171 0.297848640636702 0.446772960955053
Zfp606 ENSMUSG00000030386 1 1 0.300095920620218 0.900287761860654 0.643853282854191 0.965779924281287
Zik1 ENSMUSG00000030393 0.300095920620218 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Gtf2e2 ENSMUSG00000031585 0.244170096021948 0.522013263352776 0.348008842235184 0.522013263352776 1 1
Cnot7 ENSMUSG00000031601 0.179945789077372 0.539837367232116 0.643359829732651 0.926550375688041 0.926550375688041 0.926550375688041
Mre11a ENSMUSG00000031928 0.926333123228344 0.926333123228344 0.642864324224729 0.926333123228344 0.216214347033995 0.648643041101984
Med17 ENSMUSG00000031935 0.18064054691103 0.54192164073309 0.643853282854191 0.643853282854191 0.57466664340579 0.643853282854191
Narg2 ENSMUSG00000032235 0.851732715229127 1 0.144820068500793 0.43446020550238 1 1
Zfp944 ENSMUSG00000033972 0.147458757705094 0.442376273115283 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Dna2 ENSMUSG00000036875 0.768937368234818 0.768937368234818 0.391871008462512 0.768937368234818 0.631140429608896 0.768937368234818
Zfp157 ENSMUSG00000036898 0.255901190956604 0.511331374485819 0.340887582990546 0.511331374485819 0.643853282854191 0.643853282854191
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Psme4 ENSMUSG00000040850 0.513665062682276 0.5155648232968 0.21549027811633 0.5155648232968 0.5155648232968 0.5155648232968
Zfp445 ENSMUSG00000047036 0.216214347033995 0.255901190956604 0.179249687218049 0.255901190956604 0.255901190956604 0.255901190956604
Zfp286 ENSMUSG00000047342 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Slc38a9 ENSMUSG00000047789 0.0969812105731562 0.290943631719469 1 1 0.399548817627028 0.599323226440542
Rictor ENSMUSG00000050310 0.120545895661628 0.361637686984883 0.642864324224729 0.711854160331342 0.711854160331342 0.711854160331342
Zfp952 ENSMUSG00000053390 0.253294730253594 0.683948417459205 0.45596561163947 0.683948417459205 0.926550375688041 0.926550375688041
Skp2 ENSMUSG00000054115 0.0733738589968007 0.220121576990402 0.146800541856249 0.220200812784373 0.346899083932133 0.346899083932133
Zfp811 ENSMUSG00000055202 0.0741204440774081 0.222361332232224 0.575536202757516 0.575536202757516 0.514934023620345 0.575536202757516
AI987944 ENSMUSG00000056383 0.92622377157404 0.92622377157404 0.346899083932133 0.522566341862834 0.348377561241889 0.522566341862834
Zfp658 ENSMUSG00000056592 0.11993617140438 0.214246374477256 0.142830916318171 0.214246374477256 0.643359829732651 0.643359829732651
Zfp317 ENSMUSG00000057551 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Zfp420 ENSMUSG00000058402 0.297848640636702 0.772401035430517 0.514934023620345 0.772401035430517 0.853801250889739 0.853801250889739
Zkscan8 ENSMUSG00000063894 0.348008842235184 0.683948417459205 0.45596561163947 0.683948417459205 1 1
Zfp810 ENSMUSG00000066829 0.455625354715449 0.577829325134931 0.577829325134931 0.577829325134931 0.399907408151082 0.577829325134931
Zfp617 ENSMUSG00000066880 0.0947558980989551 0.284267694296865 0.926550375688041 0.926550375688041 0.578396848531894 0.867595272797842
Zfp760 ENSMUSG00000067928 0.147458757705094 0.442376273115283 0.85117361048289 0.85117361048289 0.397384062266614 0.596076093399921
Zfp120 ENSMUSG00000068134 0.348377561241889 0.711034989117171 0.576973746230334 0.711034989117171 0.711034989117171 0.711034989117171
Gm5595 ENSMUSG00000069727 0.119936171404379 0.359808514213138 0.397384062266614 0.453570536021945 0.453570536021945 0.453570536021945
Cited4 ENSMUSG00000070803 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.577829325134931 0.577829325134931
Gm4924 ENSMUSG00000073427 1 1 1 1 0.5155648232968 1
9830147E19Rik ENSMUSG00000074158 0.514934023620345 0.514934023620345 0.455625354715448 0.514934023620345 0.117185073436597 0.351555220309791
Etohi1 ENSMUSG00000074519 0.0241933715424143 0.0725801146272428 0.399189600887034 0.399189600887034 0.254414773803597 0.381622160705395
E430018J23Rik ENSMUSG00000078580 0.11810342389482 0.354310271684459 0.852175490580835 0.852175490580835 0.514300775319626 0.771451162979439
Smarcd2 ENSMUSG00000078619 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803 0.211844580334808 0.437634314982803
Lamtor3 ENSMUSG00000091512 0.0441715176243983 0.132514552873195 0.451840588205062 0.451840588205062 0.0969812105731563 0.145471815859735
Zfp955a ENSMUSG00000094441 0.254414773803597 0.763244321410791 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Zfp799 ENSMUSG00000095253 0.348377561241889 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968
Zfp748 ENSMUSG00000095432 0.0441715176243982 0.132514552873195 0.578113371816017 0.578113371816017 0.343537039781257 0.515305559671886
Zfp97 ENSMUSG00000095990 0.643853282854191 0.926658283600152 0.926658283600152 0.926658283600152 0.853801250889739 0.926658283600152

Generic Transcription Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tead3 ENSMUSG00000002249 0.926387617028817 0.926387617028817 0.781011212316137 0.926387617028817 0.577544706586058 0.926387617028817
Zfp81 ENSMUSG00000003929 0.299349060054895 0.449023590082343 0.453225835454266 0.453225835454266 0.148115998140416 0.444347994421247
Ywhah ENSMUSG00000018965 0.711650020253571 0.853694531487825 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Kat2a ENSMUSG00000020918 0.345037391052887 0.520348625898199 0.778911768167544 0.778911768167544 0.346899083932133 0.520348625898199
Esrrb ENSMUSG00000021255 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041 0.926550375688041 0.926550375688041
Nr1d2 ENSMUSG00000021775 0.0579478375430677 0.173843512629203 0.179945789077372 0.179945789077372 0.178901132102685 0.179945789077372
Med4 ENSMUSG00000022109 0.781170242226513 0.781170242226513 0.5155648232968 0.7733472349452 0.178901132102685 0.536703396308054
Zfp263 ENSMUSG00000022529 0.642366752097095 0.642366752097095 0.298599969973533 0.522013263352776 0.348008842235184 0.522013263352776
Dpy30 ENSMUSG00000024067 0.10607024422363 0.31821073267089 0.334323804341914 0.334323804341914 0.283134662157423 0.334323804341914
Csnk2b ENSMUSG00000024387 0.514300775319626 0.925669613555092 0.7802108304765 0.925669613555092 0.925669613555092 0.925669613555092
Ccnt2 ENSMUSG00000026349 0.343537039781257 0.515305559671885 0.179249687218049 0.515305559671885 0.643359829732651 0.643359829732651
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Trp53inp1 ENSMUSG00000028211 0.024062085667391 0.0721862570021729 0.577259514257969 0.853480389728993 0.853480389728993 0.853480389728993
Gtf2h3 ENSMUSG00000029387 0.926658283600152 0.926658283600152 0.147458757705094 0.442376273115283 0.578113371816017 0.867170057724026
Mapkapk5 ENSMUSG00000029454 0.853801250889739 0.853801250889739 0.148115998140415 0.444347994421246 0.399548817627028 0.599323226440542
Zfp12 ENSMUSG00000029587 0.00442026986621115 0.0132608095986334 0.711034989117171 0.711034989117171 0.297848640636702 0.446772960955053
Zfp606 ENSMUSG00000030386 1 1 0.300095920620218 0.900287761860654 0.643853282854191 0.965779924281287
Zik1 ENSMUSG00000030393 0.300095920620218 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Cnot7 ENSMUSG00000031601 0.179945789077372 0.539837367232116 0.643359829732651 0.926550375688041 0.926550375688041 0.926550375688041
Mre11a ENSMUSG00000031928 0.926333123228344 0.926333123228344 0.642864324224729 0.926333123228344 0.216214347033995 0.648643041101984
Med17 ENSMUSG00000031935 0.18064054691103 0.54192164073309 0.643853282854191 0.643853282854191 0.57466664340579 0.643853282854191
Zfp944 ENSMUSG00000033972 0.147458757705094 0.442376273115283 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Dna2 ENSMUSG00000036875 0.768937368234818 0.768937368234818 0.391871008462512 0.768937368234818 0.631140429608896 0.768937368234818
Zfp157 ENSMUSG00000036898 0.255901190956604 0.511331374485819 0.340887582990546 0.511331374485819 0.643853282854191 0.643853282854191
Psme4 ENSMUSG00000040850 0.513665062682276 0.5155648232968 0.21549027811633 0.5155648232968 0.5155648232968 0.5155648232968
Zfp445 ENSMUSG00000047036 0.216214347033995 0.255901190956604 0.179249687218049 0.255901190956604 0.255901190956604 0.255901190956604
Zfp286 ENSMUSG00000047342 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.216214347033995 0.648643041101984
Slc38a9 ENSMUSG00000047789 0.0969812105731562 0.290943631719469 1 1 0.399548817627028 0.599323226440542
Rictor ENSMUSG00000050310 0.120545895661628 0.361637686984883 0.642864324224729 0.711854160331342 0.711854160331342 0.711854160331342
Zfp952 ENSMUSG00000053390 0.253294730253594 0.683948417459205 0.45596561163947 0.683948417459205 0.926550375688041 0.926550375688041
Skp2 ENSMUSG00000054115 0.0733738589968007 0.220121576990402 0.146800541856249 0.220200812784373 0.346899083932133 0.346899083932133
Zfp811 ENSMUSG00000055202 0.0741204440774081 0.222361332232224 0.575536202757516 0.575536202757516 0.514934023620345 0.575536202757516
AI987944 ENSMUSG00000056383 0.92622377157404 0.92622377157404 0.346899083932133 0.522566341862834 0.348377561241889 0.522566341862834
Zfp658 ENSMUSG00000056592 0.11993617140438 0.214246374477256 0.142830916318171 0.214246374477256 0.643359829732651 0.643359829732651
Zfp317 ENSMUSG00000057551 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Zfp420 ENSMUSG00000058402 0.297848640636702 0.772401035430517 0.514934023620345 0.772401035430517 0.853801250889739 0.853801250889739
Zkscan8 ENSMUSG00000063894 0.348008842235184 0.683948417459205 0.45596561163947 0.683948417459205 1 1
Zfp810 ENSMUSG00000066829 0.455625354715449 0.577829325134931 0.577829325134931 0.577829325134931 0.399907408151082 0.577829325134931
Zfp617 ENSMUSG00000066880 0.0947558980989551 0.284267694296865 0.926550375688041 0.926550375688041 0.578396848531894 0.867595272797842
Zfp760 ENSMUSG00000067928 0.147458757705094 0.442376273115283 0.85117361048289 0.85117361048289 0.397384062266614 0.596076093399921
Zfp120 ENSMUSG00000068134 0.348377561241889 0.711034989117171 0.576973746230334 0.711034989117171 0.711034989117171 0.711034989117171
Gm5595 ENSMUSG00000069727 0.119936171404379 0.359808514213138 0.397384062266614 0.453570536021945 0.453570536021945 0.453570536021945
Cited4 ENSMUSG00000070803 0.255530331334266 0.449023590082343 0.299349060054895 0.449023590082343 0.577829325134931 0.577829325134931
Gm4924 ENSMUSG00000073427 1 1 1 1 0.5155648232968 1
9830147E19Rik ENSMUSG00000074158 0.514934023620345 0.514934023620345 0.455625354715448 0.514934023620345 0.117185073436597 0.351555220309791
Etohi1 ENSMUSG00000074519 0.0241933715424143 0.0725801146272428 0.399189600887034 0.399189600887034 0.254414773803597 0.381622160705395
E430018J23Rik ENSMUSG00000078580 0.11810342389482 0.354310271684459 0.852175490580835 0.852175490580835 0.514300775319626 0.771451162979439
Smarcd2 ENSMUSG00000078619 0.57466664340579 0.57466664340579 0.291756209988535 0.437634314982803 0.211844580334808 0.437634314982803
Lamtor3 ENSMUSG00000091512 0.0441715176243983 0.132514552873195 0.451840588205062 0.451840588205062 0.0969812105731563 0.145471815859735
Zfp955a ENSMUSG00000094441 0.254414773803597 0.763244321410791 0.926658283600152 0.926658283600152 0.782117202022501 0.926658283600152
Zfp799 ENSMUSG00000095253 0.348377561241889 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968 0.5155648232968
Zfp748 ENSMUSG00000095432 0.0441715176243982 0.132514552873195 0.578113371816017 0.578113371816017 0.343537039781257 0.515305559671886
Zfp97 ENSMUSG00000095990 0.643853282854191 0.926658283600152 0.926658283600152 0.926658283600152 0.853801250889739 0.926658283600152

Metabolism of RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0439832496172286 0.131949748851686 0.924814453025535 0.924814453025535 0.575824878403157 0.863737317604735
Hnrnph1 ENSMUSG00000007850 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Tnpo1 ENSMUSG00000009470 0.345410946355104 0.520348625898199 0.346899083932133 0.520348625898199 0.642366752097095 0.642366752097095
Prpf3 ENSMUSG00000015748 0.92589277149125 0.926003599371282 0.926003599371282 0.926003599371282 0.344663224299303 0.926003599371282
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ccar1 ENSMUSG00000020074 0.0733738589968006 0.220121576990402 0.177153312234059 0.265729968351088 0.300095920620218 0.300095920620218
Xpo1 ENSMUSG00000020290 0.119631084167591 0.358893252502774 0.853372965654504 1 1 1
Ddx52 ENSMUSG00000020677 0.398108175780842 1 1 1 0.78148726569172 1
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Tra2b ENSMUSG00000022858 0.023800255149993 0.0714007654499789 0.0756145297453647 0.113421794618047 0.926658283600152 0.926658283600152
Rpp30 ENSMUSG00000024800 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739 0.853801250889739
Wdr75 ENSMUSG00000025995 0.0238002551499929 0.0714007654499788 0.92622377157404 0.92622377157404 0.514934023620345 0.772401035430517
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
Nop56 ENSMUSG00000027405 0.577259514257969 0.865889271386954 0.926658283600152 0.926658283600152 0.348008842235184 0.865889271386954
Xrn2 ENSMUSG00000027433 0.853801250889739 0.853801250889739 0.214764523938594 0.644293571815781 0.450794830295118 0.676192245442677
Ddx20 ENSMUSG00000027905 0.0763619660358785 0.229085898107636 0.853694531487825 0.853694531487825 0.397384062266614 0.596076093399921
Tgs1 ENSMUSG00000028233 0.0241933715424143 0.0725801146272428 1 1 0.643853282854191 0.965779924281287
Tex10 ENSMUSG00000028345 0.00731348855817121 0.0219404656745136 0.782117202022501 0.853801250889739 0.853801250889739 0.853801250889739
Gtf2h3 ENSMUSG00000029387 0.926658283600152 0.926658283600152 0.147458757705094 0.442376273115283 0.578113371816017 0.867170057724026
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Cnot7 ENSMUSG00000031601 0.179945789077372 0.539837367232116 0.643359829732651 0.926550375688041 0.926550375688041 0.926550375688041
U2surp ENSMUSG00000032407 0.0964252305385472 0.289275691615642 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Rbm5 ENSMUSG00000032580 0.711854160331342 0.711854160331342 0.450794830295118 0.676192245442677 0.300095920620218 0.676192245442677
Ttc37 ENSMUSG00000033991 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Psme4 ENSMUSG00000040850 0.513665062682276 0.5155648232968 0.21549027811633 0.5155648232968 0.5155648232968 0.5155648232968
Wdr43 ENSMUSG00000041057 0.0953125666339396 0.285937699901819 0.252545530864481 0.378818296296722 0.400265374208515 0.400265374208515
Utp15 ENSMUSG00000041747 0.00159435459956481 0.00478306379869442 0.853480389728993 0.926003599371282 0.926003599371282 0.926003599371282
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Las1l ENSMUSG00000057421 0.454942951775342 0.78180291566155 0.78180291566155 0.78180291566155 0.711240436189782 0.78180291566155
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Processing of Capped Intron-Containing Pre-mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0439832496172286 0.131949748851686 0.924814453025535 0.924814453025535 0.575824878403157 0.863737317604735
Hnrnph1 ENSMUSG00000007850 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Prpf3 ENSMUSG00000015748 0.92589277149125 0.926003599371282 0.926003599371282 0.926003599371282 0.344663224299303 0.926003599371282
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ccar1 ENSMUSG00000020074 0.0733738589968006 0.220121576990402 0.177153312234059 0.265729968351088 0.300095920620218 0.300095920620218
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Tra2b ENSMUSG00000022858 0.023800255149993 0.0714007654499789 0.0756145297453647 0.113421794618047 0.926658283600152 0.926658283600152
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
U2surp ENSMUSG00000032407 0.0964252305385472 0.289275691615642 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Rbm5 ENSMUSG00000032580 0.711854160331342 0.711854160331342 0.450794830295118 0.676192245442677 0.300095920620218 0.676192245442677
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of RNA binding proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

snRNP Assembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Ddx20 ENSMUSG00000027905 0.0763619660358785 0.229085898107636 0.853694531487825 0.853694531487825 0.397384062266614 0.596076093399921
Tgs1 ENSMUSG00000028233 0.0241933715424143 0.0725801146272428 1 1 0.643853282854191 0.965779924281287
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of Mature mRNA derived from an Intron-Containing Transcript

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Metabolism of non-coding RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Ddx20 ENSMUSG00000027905 0.0763619660358785 0.229085898107636 0.853694531487825 0.853694531487825 0.397384062266614 0.596076093399921
Tgs1 ENSMUSG00000028233 0.0241933715424143 0.0725801146272428 1 1 0.643853282854191 0.965779924281287
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of ubiquitinylation proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Regulation of Glucokinase by Glucokinase Regulatory Protein

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Nuclear Pore Complex (NPC) Disassembly

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of Mature Transcript to Cytoplasm

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transcriptional regulation by small RNAs

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of DNA replication proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top2b ENSMUSG00000017485 0.252545530864481 0.378818296296722 0.167929015438906 0.378818296296722 0.513665062682276 0.513665062682276
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of the SLBP independent Mature mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of SUMOylation proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of the SLBP Dependant Mature mRNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of Mature mRNA Derived from an Intronless Transcript

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Gene Silencing by RNA

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Transport of Mature mRNAs Derived from Intronless Transcripts

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of DNA damage response and repair proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Smc5 ENSMUSG00000024943 0.180293335960318 0.540880007880955 0.643359829732651 0.643359829732651 0.399548817627028 0.599323226440542
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Nuclear Envelope Breakdown

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation of chromatin organization proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMO E3 ligases SUMOylate target proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top2b ENSMUSG00000017485 0.252545530864481 0.378818296296722 0.167929015438906 0.378818296296722 0.513665062682276 0.513665062682276
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Smc5 ENSMUSG00000024943 0.180293335960318 0.540880007880955 0.643359829732651 0.643359829732651 0.399548817627028 0.599323226440542
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Sp3 ENSMUSG00000027109 0.01710279005982 0.0513083701794599 0.0562022152993845 0.0843033229490767 0.643359829732651 0.643359829732651
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

SUMOylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Top2b ENSMUSG00000017485 0.252545530864481 0.378818296296722 0.167929015438906 0.378818296296722 0.513665062682276 0.513665062682276
Mdm2 ENSMUSG00000020184 0.0451153644990944 0.135346093497283 0.566593564630738 0.566593564630738 0.298599969973533 0.4478999549603
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Smc5 ENSMUSG00000024943 0.180293335960318 0.540880007880955 0.643359829732651 0.643359829732651 0.399548817627028 0.599323226440542
Rnf2 ENSMUSG00000026484 0.0592616003460512 0.177784801038154 0.299349060054895 0.449023590082343 0.853372965654504 0.853372965654504
Sp3 ENSMUSG00000027109 0.01710279005982 0.0513083701794599 0.0562022152993845 0.0843033229490767 0.643359829732651 0.643359829732651
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Glycolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

mRNA Splicing - Major Pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0439832496172286 0.131949748851686 0.924814453025535 0.924814453025535 0.575824878403157 0.863737317604735
Hnrnph1 ENSMUSG00000007850 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Prpf3 ENSMUSG00000015748 0.92589277149125 0.926003599371282 0.926003599371282 0.926003599371282 0.344663224299303 0.926003599371282
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ccar1 ENSMUSG00000020074 0.0733738589968006 0.220121576990402 0.177153312234059 0.265729968351088 0.300095920620218 0.300095920620218
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Tra2b ENSMUSG00000022858 0.023800255149993 0.0714007654499789 0.0756145297453647 0.113421794618047 0.926658283600152 0.926658283600152
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
U2surp ENSMUSG00000032407 0.0964252305385472 0.289275691615642 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Rbm5 ENSMUSG00000032580 0.711854160331342 0.711854160331342 0.450794830295118 0.676192245442677 0.300095920620218 0.676192245442677
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041

Regulation of HSF1-mediated heat shock response

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

mRNA Splicing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Crnkl1 ENSMUSG00000001767 0.0439832496172286 0.131949748851686 0.924814453025535 0.924814453025535 0.575824878403157 0.863737317604735
Hnrnph1 ENSMUSG00000007850 0.578113371816017 0.782117202022501 0.782117202022501 0.782117202022501 0.578113371816017 0.782117202022501
Prpf3 ENSMUSG00000015748 0.92589277149125 0.926003599371282 0.926003599371282 0.926003599371282 0.344663224299303 0.926003599371282
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Ccar1 ENSMUSG00000020074 0.0733738589968006 0.220121576990402 0.177153312234059 0.265729968351088 0.300095920620218 0.300095920620218
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Tra2b ENSMUSG00000022858 0.023800255149993 0.0714007654499789 0.0756145297453647 0.113421794618047 0.926658283600152 0.926658283600152
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
U2surp ENSMUSG00000032407 0.0964252305385472 0.289275691615642 0.254787123615605 0.382180685423408 0.643359829732651 0.643359829732651
Rbm5 ENSMUSG00000032580 0.711854160331342 0.711854160331342 0.450794830295118 0.676192245442677 0.300095920620218 0.676192245442677
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Hnrnpc ENSMUSG00000060373 0.346527959006435 0.926550375688041 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041

mRNA 3’-end processing

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Srsf6 ENSMUSG00000016921 0.926658283600152 1 1 1 0.299349060054896 0.898047180164687
Papola ENSMUSG00000021111 0.255901190956604 0.767703572869811 0.781170242226513 0.781170242226513 0.643359829732651 0.781170242226513
Srsf5 ENSMUSG00000021134 0.853694531487825 0.853694531487825 0.17924968721805 0.521459286037555 0.347639524025037 0.521459286037555
Pabpn1 ENSMUSG00000022194 0.853694531487825 0.853694531487825 0.297848640636702 0.853694531487825 0.711034989117171 0.853694531487825
Cstf3 ENSMUSG00000027176 0.400265374208515 0.600398061312773 0.853801250889739 0.853801250889739 0.34837756124189 0.600398061312773
Upf3b ENSMUSG00000036572 0.148115998140416 0.444347994421247 0.576973746230334 0.576973746230334 0.5155648232968 0.576973746230334
Thoc2 ENSMUSG00000037475 0.453570536021945 0.453570536021945 0.395928178642446 0.453570536021945 0.254414773803597 0.453570536021945

Mitotic Prometaphase

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Xpo1 ENSMUSG00000020290 0.119631084167591 0.358893252502774 0.853372965654504 1 1 1
Cenpp ENSMUSG00000021391 0.578396848531894 0.578396848531894 0.299349060054895 0.521459286037555 0.347639524025037 0.521459286037555
Csnk2b ENSMUSG00000024387 0.514300775319626 0.925669613555092 0.7802108304765 0.925669613555092 0.925669613555092 0.925669613555092
Tubgcp4 ENSMUSG00000027263 0.643359829732651 0.709375484777034 0.00283103937188883 0.00849311811566649 0.709375484777034 0.709375484777034
Cenpc1 ENSMUSG00000029253 0.0230207752632623 0.0690623257897868 0.778253541606068 0.778253541606068 0.569937449249116 0.778253541606068
Cep57 ENSMUSG00000031922 0.782117202022501 0.782117202022501 0.400265374208515 0.684457862089655 0.456305241393103 0.684457862089655
Tubgcp5 ENSMUSG00000033790 0.45596561163947 0.853694531487825 0.853694531487825 0.853694531487825 0.577829325134931 0.853694531487825
Pds5b ENSMUSG00000034021 0.0447373296833729 0.134211989050119 0.641867098978197 0.641867098978197 0.348008842235184 0.522013263352776
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Wapal ENSMUSG00000041408 0.0075577836449293 0.0226733509347879 0.18064054691103 0.270960820366545 0.853801250889739 0.853801250889739
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Cep110 ENSMUSG00000057110 0.342405296020881 0.78148726569172 0.643359829732651 0.78148726569172 0.78148726569172 0.78148726569172
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

Glucose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Nup153 ENSMUSG00000021374 0.120545895661628 0.361637686984883 0.254414773803597 0.381622160705395 1 1
Nup210 ENSMUSG00000030091 0.853694531487825 0.853694531487825 0.711034989117171 0.853694531487825 0.136475677384271 0.409427032152812
Nup54 ENSMUSG00000034826 0.0449262652924809 0.134778795877443 0.576973746230334 0.853694531487825 0.853694531487825 0.853694531487825
Nup43 ENSMUSG00000040034 0.576973746230334 0.867595272797842 1 1 0.578396848531894 0.867595272797842
Nup88 ENSMUSG00000040667 1 1 0.578396848531894 1 0.710416009055326 1
Nup160 ENSMUSG00000051329 1 1 0.78180291566155 1 0.578113371816017 1
Nup107 ENSMUSG00000052798 0.852065168704833 0.852065168704833 0.178901132102685 0.447899954960299 0.298599969973533 0.447899954960299
Seh1l ENSMUSG00000079614 0.255530331334266 0.597162263671263 0.398108175780842 0.597162263671263 0.643359829732651 0.643359829732651

darkseagreen4

Sphingolipid signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cers2 ENSMUSG00000015714 0.454600801949285 0.577829325134931 0.399548817627028 0.577829325134931 0.577829325134931 0.577829325134931
Ppp2ca ENSMUSG00000020349 0.348008842235184 0.682414427663012 0.454942951775341 0.682414427663012 0.710416009055326 0.710416009055326
Rock2 ENSMUSG00000020580 0.300095920620218 0.853907737111068 0.853907737111068 0.853907737111068 0.78180291566155 0.853907737111068
Pld2 ENSMUSG00000020828 0.514300775319626 0.711854160331342 0.711854160331342 0.711854160331342 0.578396848531894 0.711854160331342
Mapk8 ENSMUSG00000021936 0.252545530864481 0.757636592593443 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041
Plcb3 ENSMUSG00000024960 0.5155648232968 0.963550128145642 0.642366752097095 0.963550128145642 1 1
S1pr2 ENSMUSG00000043895 1 1 0.511097249598474 0.865460619345501 0.576973746230334 0.865460619345501
Trp53 ENSMUSG00000059552 0.577829325134931 0.711034989117171 0.711034989117171 0.711034989117171 0.643359829732651 0.711034989117171

darkturquoise

Morphine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pde7b ENSMUSG00000019990 0.456305241393103 0.926441990075769 0.926441990075769 0.926441990075769 0.642864324224729 0.926441990075769
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Gabra3 ENSMUSG00000031343 0.0562022152993845 0.168606645898153 0.926658283600152 0.926658283600152 0.392243127063687 0.588364690595531
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517

Adrenergic signaling in cardiomyocytes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Cacng1 ENSMUSG00000020722 0.852065168704833 0.852065168704833 0.0911326996700308 0.273398099010092 0.637013771824329 0.852065168704833
Rps6ka5 ENSMUSG00000021180 0.643853282854191 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Cacna2d3 ENSMUSG00000021991 0.78180291566155 0.78180291566155 0.113498953177704 0.340496859533111 0.395196379647461 0.592794569471191
Ppp2r2a ENSMUSG00000022052 0.57113445032749 0.57113445032749 0.346899083932133 0.520348625898199 0.17610058307789 0.520348625898199
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Scn4b ENSMUSG00000046480 0.299349060054895 0.449023590082343 0.643853282854191 0.643853282854191 0.216214347033995 0.449023590082343
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765

Purine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pde7b ENSMUSG00000019990 0.456305241393103 0.926441990075769 0.926441990075769 0.926441990075769 0.642864324224729 0.926441990075769
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Entpd8 ENSMUSG00000036813 0.179097106824913 0.404465350400709 0.269643566933806 0.404465350400709 0.562539849036184 0.562539849036184
Entpd3 ENSMUSG00000041608 0.21549027811633 0.297095062262362 0.148115998140416 0.297095062262362 0.297095062262362 0.297095062262362
Pnp2 ENSMUSG00000068417 0.78148726569172 1 1 1 0.5155648232968 1

Cortisol synthesis and secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1g ENSMUSG00000020866 0.148772260628989 0.148772260628989 0.0441715176243983 0.132514552873195 0.148772260628989 0.148772260628989
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Kcnk2 ENSMUSG00000037624 0.255901190956604 0.577259514257969 0.454942951775341 0.577259514257969 0.577259514257969 0.577259514257969
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765

Renin secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765

Neuroactive ligand-receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Gabra3 ENSMUSG00000031343 0.0562022152993845 0.168606645898153 0.926658283600152 0.926658283600152 0.392243127063687 0.588364690595531
Gpr83 ENSMUSG00000031932 0.643359829732651 0.643359829732651 0.397384062266614 0.596076093399921 0.346899083932133 0.596076093399921
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Adra2b ENSMUSG00000058620 0.853480389728993 0.853480389728993 0.640355507848752 0.853480389728993 0.78180291566155 0.853480389728993
Tac1 ENSMUSG00000061762 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825 0.513665062682276 0.853694531487825
Insl3 ENSMUSG00000079019 0.13849172243875 0.207737583658126 0.116572120727418 0.207737583658126 0.57202570269775 0.57202570269775

Circadian entrainment

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1g ENSMUSG00000020866 0.148772260628989 0.148772260628989 0.0441715176243983 0.132514552873195 0.148772260628989 0.148772260628989
Rps6ka5 ENSMUSG00000021180 0.643853282854191 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517

Dopaminergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Ppp2r2a ENSMUSG00000022052 0.57113445032749 0.57113445032749 0.346899083932133 0.520348625898199 0.17610058307789 0.520348625898199
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Gnal ENSMUSG00000024524 0.926658283600152 0.926658283600152 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652

Glutamatergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc17a8 ENSMUSG00000019935 0.578113371816017 0.578113371816017 0.148772260628989 0.446316781886967 0.454942951775341 0.578113371816017
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
PLA2G4B ENSMUSG00000098488 0.216214347033995 0.398829756175299 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299

cAMP signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652
Hhip ENSMUSG00000064325 0.45596561163947 0.5155648232968 0.5155648232968 0.5155648232968 0.514934023620345 0.5155648232968

MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pgf ENSMUSG00000004791 0.78148726569172 0.78148726569172 0.0243249029874197 0.0729747089622591 0.711034989117171 0.78148726569172
Cacng1 ENSMUSG00000020722 0.852065168704833 0.852065168704833 0.0911326996700308 0.273398099010092 0.637013771824329 0.852065168704833
Cacna1g ENSMUSG00000020866 0.148772260628989 0.148772260628989 0.0441715176243983 0.132514552873195 0.148772260628989 0.148772260628989
Rps6ka5 ENSMUSG00000021180 0.643853282854191 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Cacna2d3 ENSMUSG00000021991 0.78180291566155 0.78180291566155 0.113498953177704 0.340496859533111 0.395196379647461 0.592794569471191
Map3k8 ENSMUSG00000024235 0.578396848531894 0.926441990075769 0.926441990075769 0.926441990075769 0.711240436189781 0.926441990075769
Flnb ENSMUSG00000025278 0.393724994268831 0.393724994268831 0.252545530864481 0.383851786434906 0.255901190956604 0.383851786434906
Hgf ENSMUSG00000028864 0.346156228791382 0.866743987702397 0.577829325134931 0.866743987702397 0.926604389137101 0.926604389137101
Ptpn5 ENSMUSG00000030854 0.398108175780842 0.514934023620345 0.214037080764326 0.514934023620345 0.514934023620345 0.514934023620345
Dusp9 ENSMUSG00000031383 0.255901190956604 0.599323226440542 0.399548817627028 0.599323226440542 0.853801250889739 0.853801250889739
Ptpn7 ENSMUSG00000031506 0.13445135714101 0.250815051500687 0.51077343128446 0.51077343128446 0.167210034333791 0.250815051500687
Rasgrp2 ENSMUSG00000032946 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
PLA2G4B ENSMUSG00000098488 0.216214347033995 0.398829756175299 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299

Oxytocin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Cacng1 ENSMUSG00000020722 0.852065168704833 0.852065168704833 0.0911326996700308 0.273398099010092 0.637013771824329 0.852065168704833
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Cacna2d3 ENSMUSG00000021991 0.78180291566155 0.78180291566155 0.113498953177704 0.340496859533111 0.395196379647461 0.592794569471191
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
PLA2G4B ENSMUSG00000098488 0.216214347033995 0.398829756175299 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pparg ENSMUSG00000000440 0.852832278580641 0.852832278580641 0.0964252305385471 0.289275691615641 0.577259514257969 0.852832278580641
Lamb1 ENSMUSG00000002900 0.578396848531894 0.867595272797842 0.25141795904251 0.754253877127531 1 1
Pgf ENSMUSG00000004791 0.78148726569172 0.78148726569172 0.0243249029874197 0.0729747089622591 0.711034989117171 0.78148726569172
Wnt2 ENSMUSG00000010797 0.399548817627028 0.679838753181399 0.453225835454266 0.679838753181399 0.78180291566155 0.78180291566155
Rxrg ENSMUSG00000015843 0.454600801949285 0.681901202923927 0.711650020253571 0.711650020253571 0.399548817627028 0.681901202923927
Rarb ENSMUSG00000017491 0.514934023620344 0.772401035430517 0.853801250889739 0.853801250889739 0.454942951775341 0.772401035430517
Wnt9b ENSMUSG00000018486 0.448685536739372 0.678281806040828 0.452187870693885 0.678281806040828 0.926441990075769 0.926441990075769
Rps6ka5 ENSMUSG00000021180 0.643853282854191 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Il23a ENSMUSG00000025383 0.642615797383338 0.963923696075008 0.295201212209107 0.885603636627322 1 1
Lamb3 ENSMUSG00000026639 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068 0.710001140920767 0.853907737111068
Rad51 ENSMUSG00000027323 0.775217051297351 0.775217051297351 0.179249687218049 0.537749061654148 0.570836132666921 0.775217051297351
Hgf ENSMUSG00000028864 0.346156228791382 0.866743987702397 0.577829325134931 0.866743987702397 0.926604389137101 0.926604389137101
Rasgrp2 ENSMUSG00000032946 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Hhip ENSMUSG00000064325 0.45596561163947 0.5155648232968 0.5155648232968 0.5155648232968 0.514934023620345 0.5155648232968

Cocaine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rgs9 ENSMUSG00000020599 0.5155648232968 0.7733472349452 0.926550375688041 0.926550375688041 0.400265374208515 0.7733472349452
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652

Cushing syndrome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Wnt2 ENSMUSG00000010797 0.399548817627028 0.679838753181399 0.453225835454266 0.679838753181399 0.78180291566155 0.78180291566155
Wnt9b ENSMUSG00000018486 0.448685536739372 0.678281806040828 0.452187870693885 0.678281806040828 0.926441990075769 0.926441990075769
Cacna1g ENSMUSG00000020866 0.148772260628989 0.148772260628989 0.0441715176243983 0.132514552873195 0.148772260628989 0.148772260628989
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Kcnk2 ENSMUSG00000037624 0.255901190956604 0.577259514257969 0.454942951775341 0.577259514257969 0.577259514257969 0.577259514257969
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765

cGMP-PKG signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Creb3l3 ENSMUSG00000035041 0.853694531487825 0.853694531487825 0.300095920620218 0.450143880930327 0.11993617140438 0.359808514213139
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Adra2b ENSMUSG00000058620 0.853480389728993 0.853480389728993 0.640355507848752 0.853480389728993 0.78180291566155 0.853480389728993

Apelin signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gabarap ENSMUSG00000018567 0.119631084167592 0.358893252502775 0.709375484777034 0.709375484777034 0.577829325134931 0.709375484777034
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Pde3b ENSMUSG00000030671 0.710001140920767 0.782117202022501 0.119631084167591 0.358893252502774 0.782117202022501 0.782117202022501
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765

Chemokine signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Rasgrp2 ENSMUSG00000032946 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Shc4 ENSMUSG00000035109 0.782117202022501 0.782117202022501 0.577829325134931 0.782117202022501 0.578113371816017 0.782117202022501
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517

Platelet activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Gp9 ENSMUSG00000030054 0.00571865766267792 0.0152991142752319 0.0101994095168213 0.0152991142752319 0.376019399708591 0.376019399708591
Rasgrp2 ENSMUSG00000032946 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Gucy1a3 ENSMUSG00000033910 0.345410946355104 0.518116419532656 0.144157978128026 0.432473934384077 0.641867098978198 0.641867098978198
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
PLA2G4B ENSMUSG00000098488 0.216214347033995 0.398829756175299 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299

Hematopoietic cell lineage

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.0548979200435556 0.164693760130667 0.780851835278818 0.780851835278818 0.576112968612194 0.780851835278818
Cd4 ENSMUSG00000023274 0.115651627788147 0.346954883364442 0.577829325134931 0.577829325134931 0.348008842235184 0.522013263352777
Cd55 ENSMUSG00000026399 0.0741204440774082 0.222361332232225 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Mme ENSMUSG00000027820 0.5155648232968 0.78180291566155 0.78180291566155 0.78180291566155 0.574666643405791 0.78180291566155
Gp9 ENSMUSG00000030054 0.00571865766267792 0.0152991142752319 0.0101994095168213 0.0152991142752319 0.376019399708591 0.376019399708591
H2-DMb1 ENSMUSG00000079547 0.710416009055326 0.853801250889739 0.400265374208515 0.853801250889739 0.853801250889739 0.853801250889739

Dilated cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Itga5 ENSMUSG00000000555 0.0548979200435556 0.164693760130667 0.780851835278818 0.780851835278818 0.576112968612194 0.780851835278818
Cacng1 ENSMUSG00000020722 0.852065168704833 0.852065168704833 0.0911326996700308 0.273398099010092 0.637013771824329 0.852065168704833
Ryr2 ENSMUSG00000021313 0.297095062262363 0.782117202022501 0.782117202022501 0.782117202022501 0.576973746230334 0.782117202022501
Cacna2d3 ENSMUSG00000021991 0.78180291566155 0.78180291566155 0.113498953177704 0.340496859533111 0.395196379647461 0.592794569471191
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Lmna ENSMUSG00000028063 1 1 0.515249728559994 0.772874592839992 0.299722768420014 0.772874592839992

Serotonergic synapse

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Kcnj3 ENSMUSG00000026824 0.216214347033995 0.324321520550992 0.0441715176243983 0.132514552873195 0.926658283600152 0.926658283600152
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Kcnn2 ENSMUSG00000054477 0.514300775319626 0.514300775319626 0.0592616003460512 0.114542949053818 0.0763619660358788 0.114542949053818
PLA2G4B ENSMUSG00000098488 0.216214347033995 0.398829756175299 0.295581119060361 0.398829756175299 0.398829756175299 0.398829756175299

G alpha (i) signalling events

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lpl ENSMUSG00000015568 0.710208797518812 0.711445446052875 0.711445446052875 0.711445446052875 0.167210034333791 0.501630103001374
Rgs9 ENSMUSG00000020599 0.5155648232968 0.7733472349452 0.926550375688041 0.926550375688041 0.400265374208515 0.7733472349452
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Gnal ENSMUSG00000024524 0.926658283600152 0.926658283600152 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Rgs8 ENSMUSG00000042671 0.78180291566155 0.853907737111068 0.216214347033995 0.648643041101984 0.853907737111068 0.853907737111068
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652

Signaling by GPCR

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lpl ENSMUSG00000015568 0.710208797518812 0.711445446052875 0.711445446052875 0.711445446052875 0.167210034333791 0.501630103001374
Pde7b ENSMUSG00000019990 0.456305241393103 0.926441990075769 0.926441990075769 0.926441990075769 0.642864324224729 0.926441990075769
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Rgs9 ENSMUSG00000020599 0.5155648232968 0.7733472349452 0.926550375688041 0.926550375688041 0.400265374208515 0.7733472349452
Prkch ENSMUSG00000021108 0.711650020253571 0.853587578053106 0.853587578053106 0.853587578053106 0.642615797383338 0.853587578053106
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Gnal ENSMUSG00000024524 0.926658283600152 0.926658283600152 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517
Cd55 ENSMUSG00000026399 0.0741204440774082 0.222361332232225 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Gpr83 ENSMUSG00000031932 0.643359829732651 0.643359829732651 0.397384062266614 0.596076093399921 0.346899083932133 0.596076093399921
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Rgs8 ENSMUSG00000042671 0.78180291566155 0.853907737111068 0.216214347033995 0.648643041101984 0.853907737111068 0.853907737111068
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Arhgef39 ENSMUSG00000051517 0.853587578053106 1 1 1 0.0382382535564793 0.114714760669438
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652
Tac1 ENSMUSG00000061762 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825 0.513665062682276 0.853694531487825
Akap13 ENSMUSG00000066406 0.575824878403157 0.710416009055326 0.0162664168407234 0.0487992505221701 0.710416009055326 0.710416009055326

Signal Transduction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lamb1 ENSMUSG00000002900 0.578396848531894 0.867595272797842 0.25141795904251 0.754253877127531 1 1
Pgf ENSMUSG00000004791 0.78148726569172 0.78148726569172 0.0243249029874197 0.0729747089622591 0.711034989117171 0.78148726569172
Wnt2 ENSMUSG00000010797 0.399548817627028 0.679838753181399 0.453225835454266 0.679838753181399 0.78180291566155 0.78180291566155
Sptbn4 ENSMUSG00000011751 0.455625354715449 0.455625354715449 0.454942951775342 0.455625354715449 0.000143939694472871 0.000431819083418612
Aldh1a3 ENSMUSG00000015134 0.643853282854191 0.643853282854191 0.577259514257969 0.643853282854191 0.299349060054895 0.643853282854191
Lpl ENSMUSG00000015568 0.710208797518812 0.711445446052875 0.711445446052875 0.711445446052875 0.167210034333791 0.501630103001374
Rxrg ENSMUSG00000015843 0.454600801949285 0.681901202923927 0.711650020253571 0.711650020253571 0.399548817627028 0.681901202923927
Rarb ENSMUSG00000017491 0.514934023620344 0.772401035430517 0.853801250889739 0.853801250889739 0.454942951775341 0.772401035430517
Wnt9b ENSMUSG00000018486 0.448685536739372 0.678281806040828 0.452187870693885 0.678281806040828 0.926441990075769 0.926441990075769
Grb7 ENSMUSG00000019312 0.577829325134931 0.782117202022501 0.782117202022501 0.782117202022501 0.643853282854191 0.782117202022501
Ptprk ENSMUSG00000019889 0.578113371816017 0.578113371816017 0.454600801949285 0.578113371816017 0.577259514257969 0.578113371816017
Pde7b ENSMUSG00000019990 0.456305241393103 0.926441990075769 0.926441990075769 0.926441990075769 0.642864324224729 0.926441990075769
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Rgs9 ENSMUSG00000020599 0.5155648232968 0.7733472349452 0.926550375688041 0.926550375688041 0.400265374208515 0.7733472349452
Prkch ENSMUSG00000021108 0.711650020253571 0.853587578053106 0.853587578053106 0.853587578053106 0.642615797383338 0.853587578053106
Rps6ka5 ENSMUSG00000021180 0.643853282854191 0.852940894477647 0.852940894477647 0.852940894477647 0.578396848531894 0.852940894477647
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Strn ENSMUSG00000024077 0.711650020253571 0.78180291566155 0.78180291566155 0.78180291566155 0.348008842235184 0.78180291566155
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Gnal ENSMUSG00000024524 0.926658283600152 0.926658283600152 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517
Cd55 ENSMUSG00000026399 0.0741204440774082 0.222361332232225 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Lamb3 ENSMUSG00000026639 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068 0.710001140920767 0.853907737111068
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Hgf ENSMUSG00000028864 0.346156228791382 0.866743987702397 0.577829325134931 0.866743987702397 0.926604389137101 0.926604389137101
Evc ENSMUSG00000029122 0.514934023620345 0.772401035430517 0.926550375688041 0.926550375688041 0.255901190956604 0.767703572869812
Dusp9 ENSMUSG00000031383 0.255901190956604 0.599323226440542 0.399548817627028 0.599323226440542 0.853801250889739 0.853801250889739
Ptpn7 ENSMUSG00000031506 0.13445135714101 0.250815051500687 0.51077343128446 0.51077343128446 0.167210034333791 0.250815051500687
Cbfb ENSMUSG00000031885 0.254787123615605 0.454600801949285 0.454600801949285 0.454600801949285 0.399548817627028 0.454600801949285
Gpr83 ENSMUSG00000031932 0.643359829732651 0.643359829732651 0.397384062266614 0.596076093399921 0.346899083932133 0.596076093399921
Rasgrp2 ENSMUSG00000032946 0.78148726569172 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Diap2 ENSMUSG00000034480 0.298599969973533 0.516994836448954 0.78148726569172 0.78148726569172 0.344663224299303 0.516994836448954
Ror1 ENSMUSG00000035305 0.711034989117171 0.853372965654504 0.853372965654504 0.853372965654504 0.453225835454266 0.853372965654504
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Cyld ENSMUSG00000036712 0.853694531487825 0.853694531487825 0.0236697127745139 0.0710091383235417 0.45596561163947 0.683948417459205
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Dtx4 ENSMUSG00000039982 0.78180291566155 0.78180291566155 0.577829325134931 0.78180291566155 0.347639524025037 0.78180291566155
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Rgs8 ENSMUSG00000042671 0.78180291566155 0.853907737111068 0.216214347033995 0.648643041101984 0.853907737111068 0.853907737111068
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Prex2 ENSMUSG00000048960 0.853694531487825 0.853694531487825 0.294820734456232 0.853694531487825 0.576973746230334 0.853694531487825
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Flrt3 ENSMUSG00000051379 0.780851835278817 0.853801250889739 0.395928178642446 0.853801250889739 0.853801250889739 0.853801250889739
Arhgef39 ENSMUSG00000051517 0.853587578053106 1 1 1 0.0382382535564793 0.114714760669438
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652
Tac1 ENSMUSG00000061762 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825 0.513665062682276 0.853694531487825
Hhip ENSMUSG00000064325 0.45596561163947 0.5155648232968 0.5155648232968 0.5155648232968 0.514934023620345 0.5155648232968
Akap13 ENSMUSG00000066406 0.575824878403157 0.710416009055326 0.0162664168407234 0.0487992505221701 0.710416009055326 0.710416009055326

GPCR downstream signalling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lpl ENSMUSG00000015568 0.710208797518812 0.711445446052875 0.711445446052875 0.711445446052875 0.167210034333791 0.501630103001374
Pde7b ENSMUSG00000019990 0.456305241393103 0.926441990075769 0.926441990075769 0.926441990075769 0.642864324224729 0.926441990075769
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Pik3cg ENSMUSG00000020573 0.573791743469336 0.860687615204003 0.456305241393103 0.860687615204003 1 1
Rgs9 ENSMUSG00000020599 0.5155648232968 0.7733472349452 0.926550375688041 0.926550375688041 0.400265374208515 0.7733472349452
Prkch ENSMUSG00000021108 0.711650020253571 0.853587578053106 0.853587578053106 0.853587578053106 0.642615797383338 0.853587578053106
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Pde8b ENSMUSG00000021684 0.78180291566155 0.78180291566155 0.132758188856148 0.398274566568443 0.711034989117171 0.78180291566155
Pde1b ENSMUSG00000022489 0.297095062262363 0.867170057724026 0.926550375688041 0.926550375688041 0.578113371816017 0.867170057724026
Adcy5 ENSMUSG00000022840 0.514934023620345 0.772401035430517 0.782117202022501 0.782117202022501 0.45596561163947 0.772401035430517
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Pde10a ENSMUSG00000023868 0.514934023620345 0.772401035430517 0.92622377157404 0.92622377157404 0.300095920620218 0.772401035430517
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Gnal ENSMUSG00000024524 0.926658283600152 0.926658283600152 0.514934023620345 0.772401035430517 0.456305241393103 0.772401035430517
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Gpr83 ENSMUSG00000031932 0.643359829732651 0.643359829732651 0.397384062266614 0.596076093399921 0.346899083932133 0.596076093399921
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Plcb4 ENSMUSG00000039943 0.0382382535564793 0.0791015416550734 0.338592117141989 0.338592117141989 0.0527343611033823 0.0791015416550734
Adrbk2 ENSMUSG00000042249 0.199890020375968 0.242620429494012 0.242620429494012 0.242620429494012 0.0852666932085726 0.242620429494012
Rgs8 ENSMUSG00000042671 0.78180291566155 0.853907737111068 0.216214347033995 0.648643041101984 0.853907737111068 0.853907737111068
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Arhgef39 ENSMUSG00000051517 0.853587578053106 1 1 1 0.0382382535564793 0.114714760669438
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Ppp1r1b ENSMUSG00000061718 0.254787123615605 0.519791938509652 0.780851835278818 0.780851835278818 0.346527959006435 0.519791938509652
Tac1 ENSMUSG00000061762 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825 0.513665062682276 0.853694531487825
Akap13 ENSMUSG00000066406 0.575824878403157 0.710416009055326 0.0162664168407234 0.0487992505221701 0.710416009055326 0.710416009055326

GPCR ligand binding

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Adora2a ENSMUSG00000020178 0.299349060054895 0.599323226440542 0.926441990075769 0.926441990075769 0.399548817627028 0.599323226440542
Drd1a ENSMUSG00000021478 0.642864324224729 0.926658283600152 0.926658283600152 0.926658283600152 0.400265374208515 0.926658283600152
Cxcl13 ENSMUSG00000023078 0.51398322803049 0.926496242814507 0.711034989117171 0.926496242814507 0.926496242814507 0.926496242814507
Grm8 ENSMUSG00000024211 0.21549027811633 0.64647083434899 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041
Cd55 ENSMUSG00000026399 0.0741204440774082 0.222361332232225 0.643853282854191 0.643853282854191 0.514934023620345 0.643853282854191
Hc ENSMUSG00000026874 0.454600801949285 0.454600801949285 0.12085053136293 0.362551594088789 0.346527959006435 0.454600801949285
Ccr3 ENSMUSG00000035448 0.262418074002151 0.774525176083263 0.702215027772976 0.774525176083263 0.774525176083263 0.774525176083263
Ptger2 ENSMUSG00000037759 1 1 0.455625354715449 1 0.852940894477647 1
Adra2c ENSMUSG00000045318 0.255901190956604 0.256271555563966 0.256271555563966 0.256271555563966 0.21549027811633 0.256271555563966
Penk ENSMUSG00000045573 0.642864324224729 0.853372965654504 0.853372965654504 0.853372965654504 0.576973746230334 0.853372965654504
Gng7 ENSMUSG00000048240 0.514934023620345 0.772401035430517 0.852504981253341 0.852504981253341 0.45596561163947 0.772401035430517
Agtr1a ENSMUSG00000049115 0.7802108304765 0.7802108304765 0.577829325134931 0.7802108304765 0.711650020253571 0.7802108304765
Htr1b ENSMUSG00000049511 0.578396848531894 0.853372965654504 0.0217422311863571 0.0652266935590713 0.853372965654504 0.853372965654504
Mchr1 ENSMUSG00000050164 0.513665062682276 0.770497594023414 0.851061028660105 0.851061028660105 0.346899083932133 0.770497594023414
Fpr2 ENSMUSG00000052270 0.853480389728993 1 0.642864324224729 1 1 1
Tac1 ENSMUSG00000061762 0.78180291566155 0.853694531487825 0.853694531487825 0.853694531487825 0.513665062682276 0.853694531487825

dodgerblue4

Amyotrophic lateral sclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chmp2b ENSMUSG00000004843 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152
Nup50 ENSMUSG00000016619 0.0743693776059064 0.223108132817719 1 1 0.254414773803597 0.381622160705395
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Als2 ENSMUSG00000026024 0.148115998140415 0.268874530827074 0.853049270252403 0.853049270252403 0.17924968721805 0.268874530827074
Vcp ENSMUSG00000028452 0.573791743469336 0.638310022345193 0.638310022345193 0.638310022345193 0.255901190956604 0.638310022345193
Nup133 ENSMUSG00000039509 1 1 0.711034989117171 1 0.179945789077372 0.539837367232115
Atg2b ENSMUSG00000041341 0.300095920620218 0.450143880930327 0.853801250889739 0.853801250889739 0.18064054691103 0.450143880930327
Smcr8 ENSMUSG00000049323 0.174692232033629 0.524076696100888 0.578113371816017 0.578113371816017 0.456305241393103 0.578113371816017
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Diabetic cardiomyopathy

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Smad2 ENSMUSG00000024563 0.0592616003460512 0.177784801038154 0.577829325134931 0.577829325134931 0.453225835454266 0.577829325134931
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Oxidative phosphorylation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Parkinson disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Gnai1 ENSMUSG00000057614 0.348008842235184 0.522013263352776 0.78180291566155 0.78180291566155 0.254414773803597 0.522013263352776
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Pathways of neurodegeneration - multiple diseases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chmp2b ENSMUSG00000004843 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Als2 ENSMUSG00000026024 0.148115998140415 0.268874530827074 0.853049270252403 0.853049270252403 0.17924968721805 0.268874530827074
Vcp ENSMUSG00000028452 0.573791743469336 0.638310022345193 0.638310022345193 0.638310022345193 0.255901190956604 0.638310022345193
Atg2b ENSMUSG00000041341 0.300095920620218 0.450143880930327 0.853801250889739 0.853801250889739 0.18064054691103 0.450143880930327
Zfyve1 ENSMUSG00000042628 0.852504981253341 0.926441990075769 0.926441990075769 0.926441990075769 0.455625354715449 0.926441990075769
Smcr8 ENSMUSG00000049323 0.174692232033629 0.524076696100888 0.578113371816017 0.578113371816017 0.456305241393103 0.578113371816017
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Huntington disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Atg2b ENSMUSG00000041341 0.300095920620218 0.450143880930327 0.853801250889739 0.853801250889739 0.18064054691103 0.450143880930327
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Prion disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Alzheimer disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Vdac2 ENSMUSG00000021771 0.213307944885796 0.639923834657388 0.712057867818062 0.712057867818062 0.642366752097095 0.712057867818062
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Bace1 ENSMUSG00000032086 0.452880492349546 0.679320738524319 0.711034989117171 0.711034989117171 0.348008842235184 0.679320738524319
Atg2b ENSMUSG00000041341 0.300095920620218 0.450143880930327 0.853801250889739 0.853801250889739 0.18064054691103 0.450143880930327
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

Thermogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Adcy6 ENSMUSG00000022994 0.926550375688041 0.926550375688041 0.507168839166081 0.760753258749121 0.167569692867573 0.50270907860272
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791

RNA transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Eif4g2 ENSMUSG00000005610 0.0753654386865988 0.226096316059796 0.255901190956604 0.383851786434906 0.710416009055326 0.710416009055326
Eif1b ENSMUSG00000006941 0.252920381501207 0.37938057225181 0.85117361048289 0.85117361048289 0.0958690133561599 0.28760704006848
Nup50 ENSMUSG00000016619 0.0743693776059064 0.223108132817719 1 1 0.254414773803597 0.381622160705395
Thoc3 ENSMUSG00000025872 0.255901190956604 0.383851786434906 0.853801250889739 0.853801250889739 0.21549027811633 0.383851786434906
Eif3c ENSMUSG00000030738 0.0947558980989551 0.284267694296865 0.576973746230334 0.576973746230334 0.297848640636702 0.446772960955053
Xpot ENSMUSG00000034667 0.148115998140416 0.383295497001398 0.511097249598474 0.511097249598474 0.255530331334266 0.383295497001398
Gemin5 ENSMUSG00000037275 0.852065168704833 0.926333123228344 0.926333123228344 0.926333123228344 0.578396848531894 0.926333123228344
Rbm8a ENSMUSG00000038374 0.0592616003460512 0.177784801038154 0.710208797518812 0.710208797518812 0.12085053136293 0.181275797044394
Nup133 ENSMUSG00000039509 1 1 0.711034989117171 1 0.179945789077372 0.539837367232115
Xpo5 ENSMUSG00000067150 0.397384062266614 0.596076093399921 0.853694531487825 0.853694531487825 0.21549027811633 0.596076093399921

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlat ENSMUSG00000000168 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.255901190956604 0.767703572869812
Mthfd2 ENSMUSG00000005667 0.175044824745981 0.262567237118971 0.45596561163947 0.45596561163947 0.148115998140416 0.262567237118971
Aldh3a2 ENSMUSG00000010025 0.575824878403157 0.863737317604735 1 1 0.11993617140438 0.359808514213139
Prune ENSMUSG00000015711 0.7048795965722 0.7048795965722 0.300095920620218 0.450143880930327 0.146800541856249 0.440401625568747
Mtmr4 ENSMUSG00000018401 0.577829325134931 0.853694531487825 0.643853282854191 0.853694531487825 0.853694531487825 0.853694531487825
Acaca ENSMUSG00000020532 0.295581119060361 0.443371678590541 0.851954599472143 0.851954599472143 0.0969812105731564 0.290943631719469
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Adcy6 ENSMUSG00000022994 0.926550375688041 0.926550375688041 0.507168839166081 0.760753258749121 0.167569692867573 0.50270907860272
Aldh18a1 ENSMUSG00000025007 0.57466664340579 0.57466664340579 0.453570536021945 0.57466664340579 0.119631084167592 0.358893252502775
Gsto1 ENSMUSG00000025068 0.119631084167592 0.269918683616058 0.511097249598474 0.511097249598474 0.179945789077372 0.269918683616058
Got1 ENSMUSG00000025190 0.710416009055326 0.710416009055326 0.573498913947369 0.710416009055326 0.297848640636702 0.710416009055326
Cyp2c44 ENSMUSG00000025197 0.119020462826154 0.357061388478463 0.710622777116399 0.850835096447629 0.850835096447629 0.850835096447629
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
Prps2 ENSMUSG00000025742 0.514934023620345 0.853372965654504 0.711034989117171 0.853372965654504 0.853372965654504 0.853372965654504
Bpnt1 ENSMUSG00000026617 0.78180291566155 0.78180291566155 0.78148726569172 0.78180291566155 0.175044824745981 0.525134474237942
Slc33a1 ENSMUSG00000027822 0.348008842235184 0.643853282854191 0.643853282854191 0.643853282854191 0.643853282854191 0.643853282854191
Ears2 ENSMUSG00000030871 0.400265374208515 0.867595272797842 0.926003599371282 0.926003599371282 0.578396848531894 0.867595272797842
Alas1 ENSMUSG00000032786 0.711240436189781 0.781170242226513 0.781170242226513 0.781170242226513 0.0761127945805736 0.228338383741721
Gns ENSMUSG00000034707 0.708534948098331 0.711240436189781 0.711240436189781 0.711240436189781 0.21549027811633 0.64647083434899
Man1b1 ENSMUSG00000036646 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155 0.451840588205062 0.78180291566155
Gch1 ENSMUSG00000037580 0.146800541856249 0.440401625568746 0.710416009055326 0.710416009055326 0.514934023620345 0.710416009055326
Suv39h1 ENSMUSG00000039231 0.92589277149125 0.92589277149125 0.706616781330066 0.92589277149125 0.120850531362929 0.362551594088788
Elovl6 ENSMUSG00000041220 0.0321889748775513 0.0965669246326538 0.708323672944427 0.708323672944427 0.213307944885796 0.319961917328694
Cds2 ENSMUSG00000058793 0.853372965654504 0.853372965654504 0.852832278580641 0.853372965654504 0.180293335960318 0.540880007880955
Ipmk ENSMUSG00000060733 0.00481536616919077 0.0144460985075723 0.92589277149125 0.92589277149125 0.254787123615605 0.382180685423408
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091
mt-Nd4l ENSMUSG00000065947 0.711240436189781 0.7802108304765 0.7802108304765 0.7802108304765 0.254414773803597 0.763244321410791
Vkorc1l1 ENSMUSG00000066735 0.399548817627028 0.514934023620345 0.514934023620345 0.514934023620345 0.399548817627028 0.514934023620345

The citric acid (TCA) cycle and respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dlat ENSMUSG00000000168 0.926550375688041 0.926550375688041 0.926550375688041 0.926550375688041 0.255901190956604 0.767703572869812
Taco1 ENSMUSG00000001983 0.0579478375430677 0.173843512629203 0.633039971999413 0.633039971999413 0.17924968721805 0.268874530827074
Vdac1 ENSMUSG00000020402 0.293293089483362 0.712057867818062 0.712057867818062 0.712057867818062 0.575536202757516 0.712057867818062
Sdha ENSMUSG00000021577 0.178901132102685 0.268351698154027 0.575536202757516 0.575536202757516 0.120850531362929 0.268351698154027
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Taco1 ENSMUSG00000001983 0.0579478375430677 0.173843512629203 0.633039971999413 0.633039971999413 0.17924968721805 0.268874530827074
Atp5a1 ENSMUSG00000025428 1 1 0.926333123228344 1 0.347639524025037 1
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Atp8 ENSMUSG00000064356 1 1 0.710001140920767 1 0.255901190956604 0.767703572869812
mt-Atp6 ENSMUSG00000064357 0.710208797518812 0.781170242226513 0.781170242226513 0.781170242226513 0.216214347033995 0.648643041101984
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091

Respiratory electron transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Taco1 ENSMUSG00000001983 0.0579478375430677 0.173843512629203 0.633039971999413 0.633039971999413 0.17924968721805 0.268874530827074
mt-Nd1 ENSMUSG00000064341 0.926003599371282 0.926003599371282 0.85117361048289 0.926003599371282 0.216214347033995 0.648643041101984
mt-Nd2 ENSMUSG00000064345 0.779888212132595 0.926003599371282 0.926003599371282 0.926003599371282 0.180293335960318 0.540880007880955
mt-Co1 ENSMUSG00000064351 0.575536202757516 0.863304304136274 0.926003599371282 0.926003599371282 0.256271555563966 0.768814666691899
mt-Co2 ENSMUSG00000064354 0.399548817627028 0.599323226440542 0.782117202022501 0.782117202022501 0.348008842235184 0.599323226440542
mt-Nd4 ENSMUSG00000064363 0.852065168704833 0.92589277149125 0.92589277149125 0.92589277149125 0.18064054691103 0.541921640733091
mt-Nd6 ENSMUSG00000064368 0.010906560635693 0.032719681907079 0.455625354715449 0.455625354715449 0.178901132102685 0.268351698154027
mt-Cytb ENSMUSG00000064370 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.18064054691103 0.541921640733091

Membrane Trafficking

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chmp2b ENSMUSG00000004843 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152
Gdi1 ENSMUSG00000015291 0.447621891168214 0.447621891168214 0.399548817627028 0.447621891168214 0.0753654386865988 0.226096316059796
Nbas ENSMUSG00000020576 0.640861491578951 0.961292237368426 1 1 0.178901132102685 0.536703396308054
Tmed10 ENSMUSG00000021248 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172 0.255530331334266 0.597162263671263
Lman2 ENSMUSG00000021484 0.77858338846904 0.85117361048289 0.85117361048289 0.85117361048289 0.216214347033995 0.648643041101984
Als2 ENSMUSG00000026024 0.148115998140415 0.268874530827074 0.853049270252403 0.853049270252403 0.17924968721805 0.268874530827074
Kif26b ENSMUSG00000026494 0.576973746230334 0.78180291566155 0.78180291566155 0.78180291566155 0.148772260628989 0.446316781886968
Copa ENSMUSG00000026553 0.711034989117171 0.711034989117171 0.643853282854191 0.711034989117171 0.214764523938594 0.644293571815781
Gapvd1 ENSMUSG00000026867 0.300095920620218 0.450143880930327 0.78180291566155 0.78180291566155 0.21549027811633 0.450143880930327
Uso1 ENSMUSG00000029407 0.00768144932639895 0.0230443479791968 0.853480389728993 0.853480389728993 0.399548817627028 0.599323226440542
Scarb2 ENSMUSG00000029426 0.298599969973533 0.447899954960299 0.642366752097095 0.642366752097095 0.297848640636702 0.447899954960299
Cops7a ENSMUSG00000030127 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341 0.21549027811633 0.64647083434899
Necap1 ENSMUSG00000030327 0.120850531362929 0.120850531362929 0.111339700035808 0.120850531362929 0.0592616003460512 0.120850531362929
Cog8 ENSMUSG00000031916 0.513665062682276 0.770497594023414 0.778911768167544 0.778911768167544 0.344663224299303 0.770497594023414
Gns ENSMUSG00000034707 0.708534948098331 0.711240436189781 0.711240436189781 0.711240436189781 0.21549027811633 0.64647083434899
Sec24d ENSMUSG00000039234 0.0321889748775514 0.0888924005190768 0.511097249598474 0.511097249598474 0.0592616003460512 0.0888924005190768
Tbc1d13 ENSMUSG00000039678 0.77858338846904 0.77858338846904 0.643359829732651 0.77858338846904 0.395928178642446 0.77858338846904
Trappc5 ENSMUSG00000040236 0.572616808177226 0.710416009055326 0.513665062682276 0.710416009055326 0.710416009055326 0.710416009055326
Sec22c ENSMUSG00000061536 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.178901132102685 0.317766870502212
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501

ER to Golgi Anterograde Transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tmed10 ENSMUSG00000021248 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172 0.255530331334266 0.597162263671263
Lman2 ENSMUSG00000021484 0.77858338846904 0.85117361048289 0.85117361048289 0.85117361048289 0.216214347033995 0.648643041101984
Copa ENSMUSG00000026553 0.711034989117171 0.711034989117171 0.643853282854191 0.711034989117171 0.214764523938594 0.644293571815781
Uso1 ENSMUSG00000029407 0.00768144932639895 0.0230443479791968 0.853480389728993 0.853480389728993 0.399548817627028 0.599323226440542
Cog8 ENSMUSG00000031916 0.513665062682276 0.770497594023414 0.778911768167544 0.778911768167544 0.344663224299303 0.770497594023414
Sec24d ENSMUSG00000039234 0.0321889748775514 0.0888924005190768 0.511097249598474 0.511097249598474 0.0592616003460512 0.0888924005190768
Trappc5 ENSMUSG00000040236 0.572616808177226 0.710416009055326 0.513665062682276 0.710416009055326 0.710416009055326 0.710416009055326
Sec22c ENSMUSG00000061536 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.178901132102685 0.317766870502212
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501

COPII-mediated vesicle transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tmed10 ENSMUSG00000021248 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172 0.255530331334266 0.597162263671263
Lman2 ENSMUSG00000021484 0.77858338846904 0.85117361048289 0.85117361048289 0.85117361048289 0.216214347033995 0.648643041101984
Uso1 ENSMUSG00000029407 0.00768144932639895 0.0230443479791968 0.853480389728993 0.853480389728993 0.399548817627028 0.599323226440542
Sec24d ENSMUSG00000039234 0.0321889748775514 0.0888924005190768 0.511097249598474 0.511097249598474 0.0592616003460512 0.0888924005190768
Trappc5 ENSMUSG00000040236 0.572616808177226 0.710416009055326 0.513665062682276 0.710416009055326 0.710416009055326 0.710416009055326
Sec22c ENSMUSG00000061536 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.178901132102685 0.317766870502212

Vesicle-mediated transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chmp2b ENSMUSG00000004843 0.78180291566155 0.926658283600152 0.926658283600152 0.926658283600152 0.347639524025037 0.926658283600152
Gdi1 ENSMUSG00000015291 0.447621891168214 0.447621891168214 0.399548817627028 0.447621891168214 0.0753654386865988 0.226096316059796
Nbas ENSMUSG00000020576 0.640861491578951 0.961292237368426 1 1 0.178901132102685 0.536703396308054
Tmed10 ENSMUSG00000021248 0.398108175780842 0.597162263671263 0.78148726569172 0.78148726569172 0.255530331334266 0.597162263671263
Lman2 ENSMUSG00000021484 0.77858338846904 0.85117361048289 0.85117361048289 0.85117361048289 0.216214347033995 0.648643041101984
Als2 ENSMUSG00000026024 0.148115998140415 0.268874530827074 0.853049270252403 0.853049270252403 0.17924968721805 0.268874530827074
Kif26b ENSMUSG00000026494 0.576973746230334 0.78180291566155 0.78180291566155 0.78180291566155 0.148772260628989 0.446316781886968
Copa ENSMUSG00000026553 0.711034989117171 0.711034989117171 0.643853282854191 0.711034989117171 0.214764523938594 0.644293571815781
Gapvd1 ENSMUSG00000026867 0.300095920620218 0.450143880930327 0.78180291566155 0.78180291566155 0.21549027811633 0.450143880930327
Uso1 ENSMUSG00000029407 0.00768144932639895 0.0230443479791968 0.853480389728993 0.853480389728993 0.399548817627028 0.599323226440542
Scarb2 ENSMUSG00000029426 0.298599969973533 0.447899954960299 0.642366752097095 0.642366752097095 0.297848640636702 0.447899954960299
Cops7a ENSMUSG00000030127 0.78180291566155 0.852504981253341 0.852504981253341 0.852504981253341 0.21549027811633 0.64647083434899
Necap1 ENSMUSG00000030327 0.120850531362929 0.120850531362929 0.111339700035808 0.120850531362929 0.0592616003460512 0.120850531362929
Cog8 ENSMUSG00000031916 0.513665062682276 0.770497594023414 0.778911768167544 0.778911768167544 0.344663224299303 0.770497594023414
Gns ENSMUSG00000034707 0.708534948098331 0.711240436189781 0.711240436189781 0.711240436189781 0.21549027811633 0.64647083434899
Sec24d ENSMUSG00000039234 0.0321889748775514 0.0888924005190768 0.511097249598474 0.511097249598474 0.0592616003460512 0.0888924005190768
Tbc1d13 ENSMUSG00000039678 0.77858338846904 0.77858338846904 0.643359829732651 0.77858338846904 0.395928178642446 0.77858338846904
Trappc5 ENSMUSG00000040236 0.572616808177226 0.710416009055326 0.513665062682276 0.710416009055326 0.710416009055326 0.710416009055326
Apol9a ENSMUSG00000057346 0.643112334413352 0.643112334413352 0.454258017332816 0.643112334413352 0.174692232033629 0.524076696100888
Sec22c ENSMUSG00000061536 0.211844580334808 0.317766870502212 0.92589277149125 0.92589277149125 0.178901132102685 0.317766870502212
Tubb3 ENSMUSG00000062380 0.78180291566155 0.782117202022501 0.782117202022501 0.782117202022501 0.345037391052887 0.782117202022501

goldenrod3

[1] “No significantly overrepresented pathways reported”

grey

Gamma-carboxylation of protein precursors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.574375606171923 0.861563409257884 0.289822001432629 0.861563409257884 0.926496242814507 0.926496242814507
F7 ENSMUSG00000031443 0.575246939700399 0.575246939700399 0.451144069999285 0.575246939700399 0.0958690133561601 0.28760704006848
F10 ENSMUSG00000031444 0.850835096447629 0.850835096447629 0.776581912359068 0.850835096447629 0.220855242838515 0.662565728515546
Proz ENSMUSG00000031445 0.699013321542257 0.699013321542257 0.488993143767491 0.699013321542257 0.633577343537212 0.699013321542257

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.574375606171923 0.861563409257884 0.289822001432629 0.861563409257884 0.926496242814507 0.926496242814507
F7 ENSMUSG00000031443 0.575246939700399 0.575246939700399 0.451144069999285 0.575246939700399 0.0958690133561601 0.28760704006848
F10 ENSMUSG00000031444 0.850835096447629 0.850835096447629 0.776581912359068 0.850835096447629 0.220855242838515 0.662565728515546
Proz ENSMUSG00000031445 0.699013321542257 0.699013321542257 0.488993143767491 0.699013321542257 0.633577343537212 0.699013321542257

Removal of aminoterminal propeptides from gamma-carboxylated proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.574375606171923 0.861563409257884 0.289822001432629 0.861563409257884 0.926496242814507 0.926496242814507
F7 ENSMUSG00000031443 0.575246939700399 0.575246939700399 0.451144069999285 0.575246939700399 0.0958690133561601 0.28760704006848
F10 ENSMUSG00000031444 0.850835096447629 0.850835096447629 0.776581912359068 0.850835096447629 0.220855242838515 0.662565728515546
Proz ENSMUSG00000031445 0.699013321542257 0.699013321542257 0.488993143767491 0.699013321542257 0.633577343537212 0.699013321542257

Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
F2 ENSMUSG00000027249 0.574375606171923 0.861563409257884 0.289822001432629 0.861563409257884 0.926496242814507 0.926496242814507
F7 ENSMUSG00000031443 0.575246939700399 0.575246939700399 0.451144069999285 0.575246939700399 0.0958690133561601 0.28760704006848
F10 ENSMUSG00000031444 0.850835096447629 0.850835096447629 0.776581912359068 0.850835096447629 0.220855242838515 0.662565728515546
Proz ENSMUSG00000031445 0.699013321542257 0.699013321542257 0.488993143767491 0.699013321542257 0.633577343537212 0.699013321542257

Cell Cycle

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ube2c ENSMUSG00000001403 0.455625354715448 0.514300775319626 0.179945789077372 0.514300775319626 0.514300775319626 0.514300775319626
Dbf4 ENSMUSG00000002297 0.21549027811633 0.395196379647461 0.395196379647461 0.395196379647461 0.297848640636702 0.395196379647461
Pole ENSMUSG00000007080 0.513026869856283 0.513026869856283 0.0219958379984644 0.0329937569976966 0.0103546374915853 0.0310639124747559
Tubb1 ENSMUSG00000016255 0.185506790457697 0.278260185686546 0.498674075711114 0.498674075711114 0.185506790457697 0.278260185686546
E2f2 ENSMUSG00000018983 1 1 0.926604389137101 1 0.711854160331342 1
Dscc1 ENSMUSG00000022422 0.215852522998047 0.323778784497071 0.781645261743309 0.781645261743309 0.000690864813634747 0.00207259444090424
Stra13 ENSMUSG00000025144 0.5155648232968 0.576112968612194 0.576112968612194 0.576112968612194 0.399548817627028 0.576112968612194
Terf1 ENSMUSG00000025925 0.78180291566155 0.78180291566155 0.711034989117171 0.78180291566155 0.643853282854191 0.78180291566155
Nek2 ENSMUSG00000026622 0.25104109226111 0.67461474701903 0.449743164679353 0.67461474701903 0.711854160331342 0.711854160331342
Gins1 ENSMUSG00000027454 0.577829325134931 0.577829325134931 0.0164739112492867 0.0494217337478601 0.287873078401389 0.431809617602084
Tpx2 ENSMUSG00000027469 0.926550375688041 0.926550375688041 0.300095920620218 0.450143880930327 0.255901190956604 0.450143880930327
Aurka ENSMUSG00000027496 0.575824878403157 0.575824878403157 0.0426702157436794 0.128010647231038 0.254414773803597 0.381622160705395
Cdca8 ENSMUSG00000028873 0.853372965654504 0.853372965654504 0.058823267388015 0.176469802164045 0.452880492349546 0.679320738524319
Rfc5 ENSMUSG00000029363 0.0315593554855452 0.0473390332283179 0.11993617140438 0.11993617140438 0.00755778364492933 0.022673350934788
Ran ENSMUSG00000029430 0.295581119060361 0.450143880930327 0.452880492349546 0.452880492349546 0.300095920620218 0.450143880930327
Kif23 ENSMUSG00000032254 0.926550375688041 0.926550375688041 0.78180291566155 0.926550375688041 0.642864324224729 0.926550375688041
Fkbpl ENSMUSG00000033739 0.300095920620218 0.450143880930327 0.78148726569172 0.78148726569172 0.299349060054895 0.450143880930327
Atm ENSMUSG00000034218 0.92416823462528 1 1 1 0.323095030571162 0.969285091713486
Dync1li2 ENSMUSG00000035770 0.255901190956604 0.513665062682276 0.513665062682276 0.513665062682276 0.509144723230069 0.513665062682276
Azi1 ENSMUSG00000039781 0.513026869856283 1 0.853372965654504 1 1 1
Bub1b ENSMUSG00000040084 0.78148726569172 1 0.711650020253571 1 1 1
Mcm3 ENSMUSG00000041859 0.926604389137101 0.926604389137101 0.004593575623324 0.013780726869972 0.926604389137101 0.926604389137101
Clspn ENSMUSG00000042489 0.447621891168214 0.67143283675232 0.852504981253341 0.852504981253341 0.255901190956604 0.67143283675232
Hist1h2bg ENSMUSG00000058385 0.78180291566155 0.78180291566155 0.5155648232968 0.78180291566155 0.578113371816017 0.78180291566155
Vrk2 ENSMUSG00000064090 0.782117202022501 0.782117202022501 0.400265374208515 0.770497594023414 0.513665062682276 0.770497594023414
Hist2h2aa2 ENSMUSG00000064220 0.515249728559994 0.515249728559994 0.455284468727762 0.515249728559994 0.0967032506702096 0.290109752010629
Hist1h4m ENSMUSG00000069306 0.454600801949285 0.681901202923927 1 1 0.395928178642446 0.681901202923927
Oip5 ENSMUSG00000072980 0.782117202022501 0.926658283600152 0.926658283600152 0.926658283600152 0.17750354896016 0.532510646880481
Psme2b ENSMUSG00000078153 0.0292313579578281 0.0485204071152718 0.45149265530335 0.45149265530335 0.0323469380768478 0.0485204071152718

hotpink3

Glycolysis / Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

Biosynthesis of amino acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

D-Glutamine and D-glutamate metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gls2 ENSMUSG00000044005 0.642366752097095 0.852940894477647 0.852940894477647 0.852940894477647 0.781170242226513 0.852940894477647

Carbon metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

Glycolysis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

Glucose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tpi1 ENSMUSG00000023456 0.711034989117171 0.711034989117171 0.513665062682276 0.711034989117171 0.572616808177226 0.711034989117171
Eno3 ENSMUSG00000060600 1 1 0.926550375688041 1 0.926658283600152 1

khaki3

ECM-receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Vwf ENSMUSG00000001930 0.926333123228344 0.926333123228344 0.781170242226513 0.926333123228344 0.255901190956604 0.767703572869812
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Hspg2 ENSMUSG00000028763 0.710208797518812 0.852832278580641 0.51398322803049 0.852832278580641 0.852832278580641 0.852832278580641
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Tnxb ENSMUSG00000033327 0.575536202757515 0.863304304136272 0.926658283600152 0.926658283600152 0.454600801949285 0.863304304136272
Thbs1 ENSMUSG00000040152 0.208156293081417 0.516994836448954 0.851954599472143 0.851954599472143 0.344663224299303 0.516994836448954

Human papillomavirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Vwf ENSMUSG00000001930 0.926333123228344 0.926333123228344 0.781170242226513 0.926333123228344 0.255901190956604 0.767703572869812
Wnt11 ENSMUSG00000015957 0.249907451332337 0.249907451332337 0.21549027811633 0.249907451332337 0.147458757705094 0.249907451332337
Ppp2r3c ENSMUSG00000021022 0.297095062262362 0.597162263671263 0.398108175780842 0.597162263671263 0.78180291566155 0.78180291566155
Tcf7l2 ENSMUSG00000024985 0.146141353215796 0.260448650831748 0.346527959006435 0.346527959006435 0.173632433887832 0.260448650831748
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Wnt2b ENSMUSG00000027840 0.118409250205153 0.17761387530773 0.179597906187076 0.179597906187076 0.0572923876732157 0.171877163019647
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Tnfrsf1a ENSMUSG00000030341 0.642117186565222 0.852723421673413 0.852723421673413 0.852723421673413 0.0933633081328488 0.280089924398546
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Tnxb ENSMUSG00000033327 0.575536202757515 0.863304304136272 0.926658283600152 0.926658283600152 0.454600801949285 0.863304304136272
Ptger4 ENSMUSG00000039942 0.926333123228344 0.926333123228344 0.171859370212435 0.513040208050121 0.342026805366747 0.513040208050121
Thbs1 ENSMUSG00000040152 0.208156293081417 0.516994836448954 0.851954599472143 0.851954599472143 0.344663224299303 0.516994836448954
Fzd7 ENSMUSG00000041075 1 1 0.256271555563966 0.768814666691897 0.578113371816017 0.867170057724026
H2-Q7 ENSMUSG00000060550 0.643853282854191 0.643853282854191 0.300095920620218 0.450143880930327 0.254414773803597 0.450143880930327
H2-Q1 ENSMUSG00000079507 0.295201212209107 0.442801818313661 0.254414773803597 0.442801818313661 0.447265995733381 0.447265995733381

Proteoglycans in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Shh ENSMUSG00000002633 0.294820734456232 0.442231101684348 0.250663719290221 0.442231101684348 0.44690942336404 0.44690942336404
Wnt11 ENSMUSG00000015957 0.249907451332337 0.249907451332337 0.21549027811633 0.249907451332337 0.147458757705094 0.249907451332337
Timp3 ENSMUSG00000020044 0.78180291566155 0.78180291566155 0.300095920620217 0.593892267963669 0.395928178642446 0.593892267963669
Wnt2b ENSMUSG00000027840 0.118409250205153 0.17761387530773 0.179597906187076 0.179597906187076 0.0572923876732157 0.171877163019647
Hspg2 ENSMUSG00000028763 0.710208797518812 0.852832278580641 0.51398322803049 0.852832278580641 0.852832278580641 0.852832278580641
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Lum ENSMUSG00000036446 0.399548817627028 0.926658283600152 0.643359829732651 0.926658283600152 0.926658283600152 0.926658283600152
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Thbs1 ENSMUSG00000040152 0.208156293081417 0.516994836448954 0.851954599472143 0.851954599472143 0.344663224299303 0.516994836448954
Fzd7 ENSMUSG00000041075 1 1 0.256271555563966 0.768814666691897 0.578113371816017 0.867170057724026
Igf2 ENSMUSG00000048583 0.640861491578951 0.852832278580641 0.852832278580641 0.852832278580641 0.400265374208515 0.852832278580641
Flnc ENSMUSG00000068699 0.701310685803632 0.710208797518812 0.335495677308116 0.710208797518812 0.710208797518812 0.710208797518812

Focal adhesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Vwf ENSMUSG00000001930 0.926333123228344 0.926333123228344 0.781170242226513 0.926333123228344 0.255901190956604 0.767703572869812
Mylk ENSMUSG00000022836 0.708745765211584 0.925444427431699 0.21549027811633 0.64647083434899 0.925444427431699 0.925444427431699
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Tnxb ENSMUSG00000033327 0.575536202757515 0.863304304136272 0.926658283600152 0.926658283600152 0.454600801949285 0.863304304136272
Thbs1 ENSMUSG00000040152 0.208156293081417 0.516994836448954 0.851954599472143 0.851954599472143 0.344663224299303 0.516994836448954
Shc1 ENSMUSG00000042626 0.778911768167544 0.778911768167544 0.0334587898203823 0.0501881847305735 0.0321889748775514 0.0501881847305735
Myl9 ENSMUSG00000067818 0.144157978128026 0.432473934384077 0.710001140920767 0.710001140920767 0.389247465657472 0.583871198486208
Flnc ENSMUSG00000068699 0.701310685803632 0.710208797518812 0.335495677308116 0.710208797518812 0.710208797518812 0.710208797518812

Amoebiasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Cd14 ENSMUSG00000051439 0.514934023620345 0.578113371816017 0.216214347033995 0.578113371816017 0.578113371816017 0.578113371816017

TGF-beta signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp7 ENSMUSG00000008999 0.573791743469336 0.639337105615665 0.146800541856249 0.440401625568746 0.639337105615665 0.639337105615665
Acvr1c ENSMUSG00000026834 0.639337105615664 0.639337105615664 0.450444934184774 0.639337105615664 0.246478961478169 0.639337105615664
Thsd4 ENSMUSG00000032289 0.246478961478169 0.513026869856283 0.389247465657472 0.513026869856283 0.513026869856283 0.513026869856283
Bmp6 ENSMUSG00000039004 0.643359829732651 0.852504981253341 0.347639524025037 0.852504981253341 0.852504981253341 0.852504981253341
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Thbs1 ENSMUSG00000040152 0.208156293081417 0.516994836448954 0.851954599472143 0.851954599472143 0.344663224299303 0.516994836448954
Fmod ENSMUSG00000041559 0.781170242226513 0.781170242226513 0.287873078401389 0.676192245442677 0.450794830295118 0.676192245442677

Protein digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Eln ENSMUSG00000029675 0.572616808177226 0.575536202757516 0.575536202757516 0.575536202757516 0.399548817627028 0.575536202757516
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Kcnj13 ENSMUSG00000079436 0.569937449249116 0.569937449249116 0.392243127063687 0.569937449249116 0.453225835454266 0.569937449249116

Gastric cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shh ENSMUSG00000002633 0.294820734456232 0.442231101684348 0.250663719290221 0.442231101684348 0.44690942336404 0.44690942336404
Wnt11 ENSMUSG00000015957 0.249907451332337 0.249907451332337 0.21549027811633 0.249907451332337 0.147458757705094 0.249907451332337
Tcf7l2 ENSMUSG00000024985 0.146141353215796 0.260448650831748 0.346527959006435 0.346527959006435 0.173632433887832 0.260448650831748
Wnt2b ENSMUSG00000027840 0.118409250205153 0.17761387530773 0.179597906187076 0.179597906187076 0.0572923876732157 0.171877163019647
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Fzd7 ENSMUSG00000041075 1 1 0.256271555563966 0.768814666691897 0.578113371816017 0.867170057724026
Shc1 ENSMUSG00000042626 0.778911768167544 0.778911768167544 0.0334587898203823 0.0501881847305735 0.0321889748775514 0.0501881847305735
Fgf18 ENSMUSG00000057967 0.573498913947369 0.925444427431699 0.779888212132595 0.925444427431699 0.925444427431699 0.925444427431699

Epstein-Barr virus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tap2 ENSMUSG00000024339 0.347639524025037 0.347639524025037 0.148115998140416 0.222173997210623 0.11810342389482 0.222173997210623
Itgal ENSMUSG00000030830 0.853587578053106 0.853587578053106 0.642864324224729 0.853587578053106 0.176802739037618 0.530408217112855
Psmd7 ENSMUSG00000039067 0.575824878403157 0.77858338846904 0.77858338846904 0.77858338846904 0.395928178642446 0.77858338846904
Sin3a ENSMUSG00000042557 0.562539849036184 0.77169240001909 0.77169240001909 0.77169240001909 0.578113371816017 0.77169240001909
Oas1a ENSMUSG00000052776 0.0436072256433733 0.13082167693012 1 1 0.5155648232968 0.7733472349452
Irak4 ENSMUSG00000059883 0.509144723230069 0.852832278580641 0.852832278580641 0.852832278580641 0.852175490580835 0.852832278580641
H2-Q7 ENSMUSG00000060550 0.643853282854191 0.643853282854191 0.300095920620218 0.450143880930327 0.254414773803597 0.450143880930327
Oas1g ENSMUSG00000066861 0.640608766263372 0.925274188272099 0.640101714462795 0.925274188272099 0.925274188272099 0.925274188272099
H2-Ab1 ENSMUSG00000073421 0.78180291566155 0.78180291566155 0.781170242226513 0.78180291566155 0.295581119060361 0.78180291566155
H2-Q1 ENSMUSG00000079507 0.295201212209107 0.442801818313661 0.254414773803597 0.442801818313661 0.447265995733381 0.447265995733381

Basal cell carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Shh ENSMUSG00000002633 0.294820734456232 0.442231101684348 0.250663719290221 0.442231101684348 0.44690942336404 0.44690942336404
Wnt11 ENSMUSG00000015957 0.249907451332337 0.249907451332337 0.21549027811633 0.249907451332337 0.147458757705094 0.249907451332337
Tcf7l2 ENSMUSG00000024985 0.146141353215796 0.260448650831748 0.346527959006435 0.346527959006435 0.173632433887832 0.260448650831748
Wnt2b ENSMUSG00000027840 0.118409250205153 0.17761387530773 0.179597906187076 0.179597906187076 0.0572923876732157 0.171877163019647
Fzd7 ENSMUSG00000041075 1 1 0.256271555563966 0.768814666691897 0.578113371816017 0.867170057724026

Extracellular matrix organization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Nid1 ENSMUSG00000005397 0.777922216623952 0.777922216623952 0.146141353215796 0.438424059647387 0.642864324224729 0.777922216623952
Bmp7 ENSMUSG00000008999 0.573791743469336 0.639337105615665 0.146800541856249 0.440401625568746 0.639337105615665 0.639337105615665
Sparc ENSMUSG00000018593 1 1 0.711650020253571 1 0.175044824745981 0.525134474237942
Fbln5 ENSMUSG00000021186 0.780049698709835 0.781645261743309 0.781645261743309 0.781645261743309 0.254041925545275 0.762125776635824
Lox ENSMUSG00000024529 0.333931868690871 1 1 1 0.778747761033626 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Eln ENSMUSG00000029675 0.572616808177226 0.575536202757516 0.575536202757516 0.575536202757516 0.399548817627028 0.575536202757516
Pcolce ENSMUSG00000029718 0.216214347033995 0.576973746230334 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Mfap5 ENSMUSG00000030116 0.11810342389482 0.354310271684459 0.293293089483362 0.398829756175299 0.398829756175299 0.398829756175299
Itgal ENSMUSG00000030830 0.853587578053106 0.853587578053106 0.642864324224729 0.853587578053106 0.176802739037618 0.530408217112855
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Bgn ENSMUSG00000031375 1 1 0.21549027811633 0.64647083434899 0.852065168704833 1
Mmp15 ENSMUSG00000031790 0.447621891168214 0.851269832762335 0.926333123228344 0.926333123228344 0.567513221841557 0.851269832762335
Crtap ENSMUSG00000032431 0.57113445032749 0.640861491578951 0.573205482926791 0.640861491578951 0.640861491578951 0.640861491578951
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Tnxb ENSMUSG00000033327 0.575536202757515 0.863304304136272 0.926658283600152 0.926658283600152 0.454600801949285 0.863304304136272
Lum ENSMUSG00000036446 0.399548817627028 0.926658283600152 0.643359829732651 0.926658283600152 0.926658283600152 0.926658283600152
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Mfap4 ENSMUSG00000042436 0.926550375688041 1 1 1 0.853694531487825 1

Elastic fibre formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp7 ENSMUSG00000008999 0.573791743469336 0.639337105615665 0.146800541856249 0.440401625568746 0.639337105615665 0.639337105615665
Fbln5 ENSMUSG00000021186 0.780049698709835 0.781645261743309 0.781645261743309 0.781645261743309 0.254041925545275 0.762125776635824
Lox ENSMUSG00000024529 0.333931868690871 1 1 1 0.778747761033626 1
Eln ENSMUSG00000029675 0.572616808177226 0.575536202757516 0.575536202757516 0.575536202757516 0.399548817627028 0.575536202757516
Mfap5 ENSMUSG00000030116 0.11810342389482 0.354310271684459 0.293293089483362 0.398829756175299 0.398829756175299 0.398829756175299
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Mfap4 ENSMUSG00000042436 0.926550375688041 1 1 1 0.853694531487825 1

Laminin interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Nid1 ENSMUSG00000005397 0.777922216623952 0.777922216623952 0.146141353215796 0.438424059647387 0.642864324224729 0.777922216623952
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092

MET activates PTK2 signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092

Crosslinking of collagen fibrils

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Lox ENSMUSG00000024529 0.333931868690871 1 1 1 0.778747761033626 1
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Pcolce ENSMUSG00000029718 0.216214347033995 0.576973746230334 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381

Molecules associated with elastic fibres

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bmp7 ENSMUSG00000008999 0.573791743469336 0.639337105615665 0.146800541856249 0.440401625568746 0.639337105615665 0.639337105615665
Fbln5 ENSMUSG00000021186 0.780049698709835 0.781645261743309 0.781645261743309 0.781645261743309 0.254041925545275 0.762125776635824
Eln ENSMUSG00000029675 0.572616808177226 0.575536202757516 0.575536202757516 0.575536202757516 0.399548817627028 0.575536202757516
Mfap5 ENSMUSG00000030116 0.11810342389482 0.354310271684459 0.293293089483362 0.398829756175299 0.398829756175299 0.398829756175299
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Mfap4 ENSMUSG00000042436 0.926550375688041 1 1 1 0.853694531487825 1

Integrin cell surface interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Itgal ENSMUSG00000030830 0.853587578053106 0.853587578053106 0.642864324224729 0.853587578053106 0.176802739037618 0.530408217112855
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lum ENSMUSG00000036446 0.399548817627028 0.926658283600152 0.643359829732651 0.926658283600152 0.926658283600152 0.926658283600152

MET promotes cell motility

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092

ECM proteoglycans

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Sparc ENSMUSG00000018593 1 1 0.711650020253571 1 0.175044824745981 0.525134474237942
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Bgn ENSMUSG00000031375 1 1 0.21549027811633 0.64647083434899 0.852065168704833 1
Tnxb ENSMUSG00000033327 0.575536202757515 0.863304304136272 0.926658283600152 0.926658283600152 0.454600801949285 0.863304304136272

Collagen biosynthesis and modifying enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Pcolce ENSMUSG00000029718 0.216214347033995 0.576973746230334 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Crtap ENSMUSG00000032431 0.57113445032749 0.640861491578951 0.573205482926791 0.640861491578951 0.640861491578951 0.640861491578951

Assembly of collagen fibrils and other multimeric structures

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Lox ENSMUSG00000024529 0.333931868690871 1 1 1 0.778747761033626 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Pcolce ENSMUSG00000029718 0.216214347033995 0.576973746230334 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381

Collagen formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Lox ENSMUSG00000024529 0.333931868690871 1 1 1 0.778747761033626 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Pcolce ENSMUSG00000029718 0.216214347033995 0.576973746230334 0.576973746230334 0.576973746230334 0.513026869856283 0.576973746230334
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Crtap ENSMUSG00000032431 0.57113445032749 0.640861491578951 0.573205482926791 0.640861491578951 0.640861491578951 0.640861491578951

Smooth Muscle Contraction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Mylk ENSMUSG00000022836 0.708745765211584 0.925444427431699 0.21549027811633 0.64647083434899 0.925444427431699 0.925444427431699
Tpm2 ENSMUSG00000028464 0.294820734456232 0.596076093399921 0.397384062266614 0.596076093399921 0.850151080737202 0.850151080737202
Cald1 ENSMUSG00000029761 0.573205482926791 0.573205482926791 0.299349060054895 0.449023590082343 0.093084640707941 0.279253922123823
Acta2 ENSMUSG00000035783 0.393724994268831 0.590587491403246 1 1 0.295581119060361 0.590587491403246
Myl9 ENSMUSG00000067818 0.144157978128026 0.432473934384077 0.710001140920767 0.710001140920767 0.389247465657472 0.583871198486208

Collagen degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Mmp15 ENSMUSG00000031790 0.447621891168214 0.851269832762335 0.926333123228344 0.926333123228344 0.567513221841557 0.851269832762335

Organic anion transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc22a6 ENSMUSG00000024650 0.57466664340579 0.576973746230334 0.576973746230334 0.576973746230334 0.455625354715448 0.576973746230334
Slc22a8 ENSMUSG00000063796 0.141833111438997 0.425499334316992 0.711034989117171 0.853372965654504 0.853372965654504 0.853372965654504

Transfer of LPS from LBP carrier to CD14

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lbp ENSMUSG00000016024 0.926333123228344 0.926333123228344 0.148772260628989 0.442231101684348 0.294820734456232 0.442231101684348
Cd14 ENSMUSG00000051439 0.514934023620345 0.578113371816017 0.216214347033995 0.578113371816017 0.578113371816017 0.578113371816017

Collagen chain trimerization

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381

Signaling by MET

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092

Signaling by Receptor Tyrosine Kinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Itga3 ENSMUSG00000001507 0.297095062262363 0.347639524025037 0.347639524025037 0.347639524025037 0.298599969973533 0.347639524025037
Ncf1 ENSMUSG00000015950 0.852940894477647 0.852940894477647 0.0113901882503033 0.0341705647509099 0.0703913497478892 0.105587024621834
Frs3 ENSMUSG00000023266 0.710416009055326 0.711854160331342 0.711854160331342 0.711854160331342 0.11993617140438 0.359808514213139
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Lamc3 ENSMUSG00000026840 0.576973746230334 0.576973746230334 0.576973746230334 0.576973746230334 0.509144723230069 0.576973746230334
Sh2d2a ENSMUSG00000028071 0.44004840871096 0.696185305392667 0.68402078027356 0.696185305392667 0.696185305392667 0.696185305392667
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Lama1 ENSMUSG00000032796 0.85117361048289 0.925669613555092 0.925217182211634 0.925669613555092 0.925669613555092 0.925669613555092
Prr5 ENSMUSG00000036106 0.508488713161374 0.513665062682276 0.509144723230069 0.513665062682276 0.513665062682276 0.513665062682276
Igf2 ENSMUSG00000048583 0.640861491578951 0.852832278580641 0.852832278580641 0.852832278580641 0.400265374208515 0.852832278580641
Fes ENSMUSG00000053158 0.455625354715449 0.643359829732651 0.643359829732651 0.643359829732651 0.214037080764325 0.642111242292976
Fgf18 ENSMUSG00000057967 0.573498913947369 0.925444427431699 0.779888212132595 0.925444427431699 0.925444427431699 0.925444427431699
Kl ENSMUSG00000058488 0.450444934184774 0.508817043656046 0.384286524841344 0.508817043656046 0.508817043656046 0.508817043656046

Anchoring fibril formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381

Degradation of the extracellular matrix

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col18a1 ENSMUSG00000001435 0.453225835454266 0.453225835454266 0.399189600887034 0.453225835454266 0.0314025154922879 0.0942075464768637
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Nid1 ENSMUSG00000005397 0.777922216623952 0.777922216623952 0.146141353215796 0.438424059647387 0.642864324224729 0.777922216623952
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Eln ENSMUSG00000029675 0.572616808177226 0.575536202757516 0.575536202757516 0.575536202757516 0.399548817627028 0.575536202757516
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381
Mmp15 ENSMUSG00000031790 0.447621891168214 0.851269832762335 0.926333123228344 0.926333123228344 0.567513221841557 0.851269832762335

Platelet degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sparc ENSMUSG00000018593 1 1 0.711650020253571 1 0.175044824745981 0.525134474237942
Timp3 ENSMUSG00000020044 0.78180291566155 0.78180291566155 0.300095920620217 0.593892267963669 0.395928178642446 0.593892267963669
Serping1 ENSMUSG00000023224 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739 0.711854160331342 0.853801250889739
Maged2 ENSMUSG00000025268 0.115037265385284 0.269918683616058 0.454600801949285 0.454600801949285 0.179945789077372 0.269918683616058
Selp ENSMUSG00000026580 1 1 0.825207865239073 1 0.913630013845377 1
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Igf2 ENSMUSG00000048583 0.640861491578951 0.852832278580641 0.852832278580641 0.852832278580641 0.400265374208515 0.852832278580641

Non-integrin membrane-ECM interactions

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Col1a1 ENSMUSG00000001506 1 1 0.397746436553874 1 0.710208797518812 1
Col3a1 ENSMUSG00000026043 0.706831781264721 0.706831781264721 0.639337105615665 0.706831781264721 0.706616781330066 0.706831781264721
Col1a2 ENSMUSG00000029661 0.499022251664193 0.499022251664193 0.297095062262362 0.445642593393544 0.240671523582595 0.445642593393544
Col4a5 ENSMUSG00000031274 0.853480389728993 0.853480389728993 0.78148726569172 0.853480389728993 0.0566379395854602 0.169913818756381

Response to elevated platelet cytosolic Ca2+

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sparc ENSMUSG00000018593 1 1 0.711650020253571 1 0.175044824745981 0.525134474237942
Timp3 ENSMUSG00000020044 0.78180291566155 0.78180291566155 0.300095920620217 0.593892267963669 0.395928178642446 0.593892267963669
Serping1 ENSMUSG00000023224 0.853801250889739 0.853801250889739 0.711650020253571 0.853801250889739 0.711854160331342 0.853801250889739
Maged2 ENSMUSG00000025268 0.115037265385284 0.269918683616058 0.454600801949285 0.454600801949285 0.179945789077372 0.269918683616058
Selp ENSMUSG00000026580 1 1 0.825207865239073 1 0.913630013845377 1
Tgfb2 ENSMUSG00000039239 0.701537542765341 0.701537542765341 0.144820068500793 0.416242791166537 0.277495194111025 0.416242791166537
Igf2 ENSMUSG00000048583 0.640861491578951 0.852832278580641 0.852832278580641 0.852832278580641 0.400265374208515 0.852832278580641

lavenderblush2

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Sirt2 ENSMUSG00000015149 0.148115998140416 0.270440003940477 0.514300775319626 0.514300775319626 0.180293335960318 0.270440003940477
Qdpr ENSMUSG00000015806 0.148115998140416 0.444347994421247 0.92622377157404 0.92622377157404 0.508488713161374 0.762733069742061
Chdh ENSMUSG00000015970 0.343537039781257 0.600398061312773 0.400265374208515 0.600398061312773 1 1
Adi1 ENSMUSG00000020629 0.29252580908486 0.677760882307593 0.451840588205062 0.677760882307593 0.711034989117171 0.711034989117171
Pde8a ENSMUSG00000025584 0.343537039781257 0.5155648232968 0.454600801949285 0.5155648232968 0.5155648232968 0.5155648232968
Acadl ENSMUSG00000026003 0.121155015244363 0.208897379073412 0.148115998140416 0.208897379073412 0.208897379073412 0.208897379073412
Gatm ENSMUSG00000027199 0.253294730253594 0.759884190760783 0.577829325134931 0.866743987702397 0.926658283600152 0.926658283600152
Crls1 ENSMUSG00000027357 0.21549027811633 0.323235417174494 0.120850531362929 0.323235417174494 0.779238691542963 0.779238691542963
Lpin3 ENSMUSG00000027412 0.451840588205062 0.677760882307593 0.780851835278818 0.780851835278818 0.397384062266614 0.677760882307593
Car2 ENSMUSG00000027562 0.0116356061791785 0.0349068185375355 0.0741204440774082 0.111180666116112 0.178901132102685 0.178901132102685
Hadh ENSMUSG00000027984 0.00755778364492931 0.0226733509347879 0.711240436189781 0.711240436189781 0.348008842235184 0.522013263352777
Ugt8a ENSMUSG00000032854 0.294820734456232 0.638824656785692 0.638824656785692 0.638824656785692 0.513665062682276 0.638824656785692
Galnt6 ENSMUSG00000037280 0.214764523938594 0.644293571815781 0.926550375688041 0.926550375688041 0.711854160331342 0.926550375688041
Gal3st1 ENSMUSG00000049721 0.0964252305385472 0.289275691615642 0.29252580908486 0.438788713627291 0.569937449249116 0.569937449249116
Phgdh ENSMUSG00000053398 0.17924968721805 0.383851786434905 0.255901190956604 0.383851786434905 0.454942951775342 0.454942951775342
Gstm1 ENSMUSG00000058135 0.211844580334808 0.635533741004424 0.711650020253571 0.711650020253571 0.511742979522636 0.711650020253571
Selenbp1 ENSMUSG00000068874 0.17924968721805 0.268874530827074 0.578113371816017 0.578113371816017 0.117185073436597 0.268874530827074

Glycine, serine and threonine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Chdh ENSMUSG00000015970 0.343537039781257 0.600398061312773 0.400265374208515 0.600398061312773 1 1
Gatm ENSMUSG00000027199 0.253294730253594 0.759884190760783 0.577829325134931 0.866743987702397 0.926658283600152 0.926658283600152
Phgdh ENSMUSG00000053398 0.17924968721805 0.383851786434905 0.255901190956604 0.383851786434905 0.454942951775342 0.454942951775342

lightblue

Metabolism of Angiotensinogen to Angiotensins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cpb1 ENSMUSG00000011463 0.781645261743309 0.853694531487825 0.711445446052875 0.853694531487825 0.853694531487825 0.853694531487825
Cma1 ENSMUSG00000022225 0.650262661949838 0.650262661949838 0.650262661949838 0.650262661949838 0.280002632651122 0.650262661949838

Peptide hormone metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cpb1 ENSMUSG00000011463 0.781645261743309 0.853694531487825 0.711445446052875 0.853694531487825 0.853694531487825 0.853694531487825
Cma1 ENSMUSG00000022225 0.650262661949838 0.650262661949838 0.650262661949838 0.650262661949838 0.280002632651122 0.650262661949838

lightgoldenrod3

Proteoglycans in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Stat3 ENSMUSG00000004040 0.342026805366747 0.51304020805012 0.0953125666339397 0.285937699901819 0.853801250889739 0.853801250889739
Tfap4 ENSMUSG00000005718 0.852065168704833 0.852065168704833 0.0763619660358786 0.229085898107636 0.447621891168214 0.67143283675232
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Sdc4 ENSMUSG00000017009 0.400265374208515 0.600398061312773 0.710208797518812 0.710208797518812 0.299349060054895 0.600398061312773
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Frs2 ENSMUSG00000020170 0.513026869856283 0.513026869856283 0.178901132102685 0.370292939183197 0.246861959455465 0.370292939183197
Sdc1 ENSMUSG00000020592 1 1 0.345037391052888 1 0.853372965654504 1
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Itgb5 ENSMUSG00000022817 0.0236697127745139 0.0648478400701163 0.514934023620344 0.514934023620344 0.0432318933800775 0.0648478400701163
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Itpr2 ENSMUSG00000030287 0.708534948098331 0.708534948098331 0.640861491578951 0.708534948098331 0.0566379395854604 0.169913818756381
Iqgap1 ENSMUSG00000030536 0.575824878403157 0.863737317604735 0.0969812105731562 0.290943631719469 1 1
Cttn ENSMUSG00000031078 0.254787123615605 0.764361370846816 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Msn ENSMUSG00000031207 0.511742979522636 0.767614469283954 0.148772260628989 0.446316781886967 0.926333123228344 0.926333123228344
Ank1 ENSMUSG00000031543 0.294820734456232 0.442231101684348 0.0588232673880148 0.176469802164045 0.711034989117171 0.711034989117171
Mmp2 ENSMUSG00000031740 0.248769231421035 0.373153847131552 0.853480389728993 0.853480389728993 0.0318737159052625 0.0956211477157874
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Ppp1ca ENSMUSG00000040385 0.180293335960318 0.540880007880954 0.852175490580835 1 1 1
Itpr3 ENSMUSG00000042644 0.338592117141989 0.507888175712984 0.180293335960318 0.507888175712984 0.710416009055326 0.710416009055326
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Eif4b ENSMUSG00000058655 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.451840588205062 0.640355507848752 0.640355507848752 0.640355507848752 0.254787123615605 0.640355507848752
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Daxx ENSMUSG00000002307 0.5155648232968 0.5155648232968 0.454600801949285 0.5155648232968 0.148115998140416 0.444347994421247
Efna2 ENSMUSG00000003070 0.852940894477647 0.852940894477647 0.0158546704257246 0.0475640112771739 0.173632433887832 0.260448650831748
Map3k11 ENSMUSG00000004054 0.926658283600152 0.926658283600152 0.25141795904251 0.754253877127531 0.5155648232968 0.7733472349452
Hspb1 ENSMUSG00000004951 0.853694531487825 0.853694531487825 0.782117202022501 0.853694531487825 0.514934023620345 0.853694531487825
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Tek ENSMUSG00000006386 0.0241933715424143 0.0725801146272428 1 1 0.120850531362929 0.181275797044394
Epha2 ENSMUSG00000006445 1 1 0.17750354896016 0.53251064688048 0.78148726569172 1
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Map3k4 ENSMUSG00000014426 0.213307944885796 0.323235417174495 0.443669460449296 0.443669460449296 0.21549027811633 0.323235417174495
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Map2k6 ENSMUSG00000020623 1 1 0.712057867818062 1 1 1
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Ddit3 ENSMUSG00000025408 0.179945789077372 0.269918683616058 0.395196379647461 0.395196379647461 0.0953125666339398 0.269918683616058
Map4k4 ENSMUSG00000026074 0.643853282854191 0.643853282854191 0.17610058307789 0.528301749233671 0.398829756175299 0.598244634262948
Mecom ENSMUSG00000027684 0.179597906187076 0.538793718561228 0.71082910328023 0.71082910328023 0.643112334413352 0.71082910328023
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Efna1 ENSMUSG00000027954 0.148115998140416 0.222173997210623 1 1 0.09586901335616 0.222173997210623
Flt1 ENSMUSG00000029648 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.148772260628989 0.446316781886968
Dusp16 ENSMUSG00000030203 0.576973746230334 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781 0.711240436189781
Dusp4 ENSMUSG00000031530 0.148772260628989 0.446316781886968 0.343537039781257 0.515305559671886 0.578113371816017 0.578113371816017
Rasgrf1 ENSMUSG00000032356 0.144820068500793 0.43446020550238 0.706616781330066 0.706616781330066 0.346527959006435 0.519791938509653
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Map3k13 ENSMUSG00000033618 0.167569692867573 0.50270907860272 0.513665062682276 0.640861491578951 0.640861491578951 0.640861491578951
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Dusp8 ENSMUSG00000037887 0.853801250889739 0.853801250889739 0.853694531487825 0.853801250889739 0.711854160331342 0.853801250889739
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Dusp10 ENSMUSG00000039384 0.456305241393103 0.456305241393103 0.179945789077372 0.456305241393103 0.399548817627028 0.456305241393103
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Ntrk2 ENSMUSG00000055254 0.576112968612194 0.643853282854191 0.643853282854191 0.643853282854191 0.252920381501207 0.643853282854191
Max ENSMUSG00000059436 0.0741204440774082 0.222361332232225 0.254787123615605 0.346899083932133 0.346899083932133 0.346899083932133
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Hspa2 ENSMUSG00000059970 0.78148726569172 0.78148726569172 0.5155648232968 0.7733472349452 0.514934023620344 0.7733472349452
Taok2 ENSMUSG00000059981 0.255530331334266 0.711034989117171 0.711034989117171 0.711034989117171 0.710416009055326 0.711034989117171
Ppm1b ENSMUSG00000061130 0.578113371816017 0.926441990075769 0.926441990075769 0.926441990075769 0.852832278580641 0.926441990075769
Taok3 ENSMUSG00000061288 0.57466664340579 0.57466664340579 0.514934023620345 0.57466664340579 0.5155648232968 0.57466664340579
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Ecsit ENSMUSG00000066839 0.577259514257969 0.711650020253571 0.179945789077372 0.539837367232116 0.711650020253571 0.711650020253571
Cacng7 ENSMUSG00000069806 0.926441990075769 0.926441990075769 0.0241933715424143 0.0725801146272428 0.926441990075769 0.926441990075769
Jund ENSMUSG00000071076 0.782117202022501 0.853907737111068 0.853907737111068 0.853907737111068 0.853801250889739 0.853907737111068
Hspa1a ENSMUSG00000091971 0.255530331334266 0.711650020253571 0.711650020253571 0.711650020253571 0.643359829732651 0.711650020253571

Adherens junction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Ptprb ENSMUSG00000020154 0.300095920620218 0.450143880930327 0.926550375688041 0.926550375688041 0.21549027811633 0.450143880930327
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Iqgap1 ENSMUSG00000030536 0.575824878403157 0.863737317604735 0.0969812105731562 0.290943631719469 1 1
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Ptprm ENSMUSG00000033278 0.340887582990546 0.340887582990546 0.113498953177704 0.340496859533111 0.300095920620218 0.340887582990546
Ptprf ENSMUSG00000033295 0.398829756175299 0.598244634262948 0.926550375688041 0.926550375688041 0.214037080764326 0.598244634262948
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Acp1 ENSMUSG00000044573 0.454600801949285 0.681901202923927 0.0964252305385473 0.289275691615642 0.711854160331342 0.711854160331342
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Ras signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Efna2 ENSMUSG00000003070 0.852940894477647 0.852940894477647 0.0158546704257246 0.0475640112771739 0.173632433887832 0.260448650831748
Gab2 ENSMUSG00000004508 0.570836132666921 0.570836132666921 0.253294730253594 0.438788713627291 0.29252580908486 0.438788713627291
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Tek ENSMUSG00000006386 0.0241933715424143 0.0725801146272428 1 1 0.120850531362929 0.181275797044394
Epha2 ENSMUSG00000006445 1 1 0.17750354896016 0.53251064688048 0.78148726569172 1
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Abl1 ENSMUSG00000026842 0.643359829732651 0.853801250889739 0.300095920620218 0.853801250889739 0.853801250889739 0.853801250889739
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Efna1 ENSMUSG00000027954 0.148115998140416 0.222173997210623 1 1 0.09586901335616 0.222173997210623
Pla2g2c ENSMUSG00000028750 0.926496242814507 0.926496242814507 0.147787500009832 0.221681250014749 0.120241108790035 0.221681250014749
Flt1 ENSMUSG00000029648 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.148772260628989 0.446316781886968
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Ets1 ENSMUSG00000032035 0.0449262652924809 0.134778795877443 1 1 0.180293335960318 0.270440003940477
Rasgrf1 ENSMUSG00000032356 0.144820068500793 0.43446020550238 0.706616781330066 0.706616781330066 0.346527959006435 0.519791938509653
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Pla2g3 ENSMUSG00000034579 0.926550375688041 0.926550375688041 0.0964252305385472 0.289275691615642 0.578113371816017 0.867170057724026
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Pla2g6 ENSMUSG00000042632 0.254787123615605 0.254787123615605 0.254414773803597 0.254787123615605 0.254414773803597 0.254787123615605
Foxo4 ENSMUSG00000042903 0.120241108790035 0.295201212209107 0.295201212209107 0.295201212209107 0.255158975839805 0.295201212209107
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Ntrk2 ENSMUSG00000055254 0.576112968612194 0.643853282854191 0.643853282854191 0.643853282854191 0.252920381501207 0.643853282854191
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Focal adhesion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Lama5 ENSMUSG00000015647 0.643853282854191 0.643853282854191 0.576973746230334 0.643853282854191 0.297095062262362 0.643853282854191
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Lama2 ENSMUSG00000019899 0.297095062262362 0.297095062262362 0.170434860179341 0.255652290269012 0.0741204440774082 0.222361332232225
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Parvb ENSMUSG00000022438 0.926550375688041 0.926550375688041 0.45596561163947 0.683948417459205 0.179945789077372 0.539837367232115
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Itgb5 ENSMUSG00000022817 0.0236697127745139 0.0648478400701163 0.514934023620344 0.514934023620344 0.0432318933800775 0.0648478400701163
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Capn2 ENSMUSG00000026509 0.85117361048289 0.85117361048289 0.0763619660358786 0.229085898107636 0.513665062682276 0.770497594023414
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Flt1 ENSMUSG00000029648 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.148772260628989 0.446316781886968
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Rasgrf1 ENSMUSG00000032356 0.144820068500793 0.43446020550238 0.706616781330066 0.706616781330066 0.346527959006435 0.519791938509653
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Chad ENSMUSG00000039084 0.850265736951714 0.850265736951714 0.705098431925329 0.850265736951714 0.705098431925329 0.850265736951714
Itga9 ENSMUSG00000039115 0.397384062266614 0.682414427663012 0.926550375688041 0.926550375688041 0.454942951775342 0.682414427663012
Ppp1ca ENSMUSG00000040385 0.180293335960318 0.540880007880954 0.852175490580835 1 1 1
Itga1 ENSMUSG00000042284 0.926550375688041 0.926550375688041 0.395928178642446 0.593892267963669 0.299349060054895 0.593892267963669
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Tln2 ENSMUSG00000052698 0.577259514257968 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Lamb2 ENSMUSG00000052911 0.399548817627028 0.599323226440542 1 1 0.180293335960318 0.540880007880955
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Hippo signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Bbc3 ENSMUSG00000002083 0.21549027811633 0.21549027811633 0.146141353215796 0.21549027811633 0.177153312234059 0.21549027811633
Nf2 ENSMUSG00000009073 0.78148726569172 0.78148726569172 0.400265374208515 0.682414427663012 0.454942951775341 0.682414427663012
Birc5 ENSMUSG00000017716 0.852504981253341 0.852504981253341 0.456305241393103 0.684457862089655 0.254414773803597 0.684457862089655
Ywhae ENSMUSG00000020849 0.576973746230334 0.643359829732651 0.45596561163947 0.643359829732651 0.643359829732651 0.643359829732651
Sav1 ENSMUSG00000021067 0.0761127945805736 0.11416919187086 0.0586042534833404 0.11416919187086 0.926387617028817 0.926387617028817
Lats2 ENSMUSG00000021959 0.205174703261494 0.307762054892242 0.180293335960318 0.307762054892242 0.572616808177226 0.572616808177226
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Dlg1 ENSMUSG00000022770 0.781170242226513 1 1 1 0.148115998140415 0.444347994421246
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Smad7 ENSMUSG00000025880 1 1 0.148772260628989 0.446316781886967 0.300095920620218 0.450143880930327
Wwtr1 ENSMUSG00000027803 0.453225835454266 0.679838753181399 0.453225835454266 0.679838753181399 0.711854160331342 0.711854160331342
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Tead4 ENSMUSG00000030353 0.150680196006792 0.452040588020376 0.442941842468822 0.547581719820537 0.547581719820537 0.547581719820537
Smad1 ENSMUSG00000031681 0.0171027900598199 0.0513083701794598 0.57113445032749 0.578113371816017 0.578113371816017 0.578113371816017
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Ppp1ca ENSMUSG00000040385 0.180293335960318 0.540880007880954 0.852175490580835 1 1 1
Pard6b ENSMUSG00000044641 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Dlg2 ENSMUSG00000052572 0.926550375688041 0.926550375688041 0.853907737111068 0.926550375688041 0.577829325134931 0.926550375688041
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993

Pathways in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.451840588205062 0.640355507848752 0.640355507848752 0.640355507848752 0.254787123615605 0.640355507848752
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Jup ENSMUSG00000001552 0.853372965654504 1 0.300095920620218 0.900287761860653 1 1
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Bbc3 ENSMUSG00000002083 0.21549027811633 0.21549027811633 0.146141353215796 0.21549027811633 0.177153312234059 0.21549027811633
Jag2 ENSMUSG00000002799 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.0756145297453649 0.226843589236095
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Stat3 ENSMUSG00000004040 0.342026805366747 0.51304020805012 0.0953125666339397 0.285937699901819 0.853801250889739 0.853801250889739
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Lama5 ENSMUSG00000015647 0.643853282854191 0.643853282854191 0.576973746230334 0.643853282854191 0.297095062262362 0.643853282854191
Birc5 ENSMUSG00000017716 0.852504981253341 0.852504981253341 0.456305241393103 0.684457862089655 0.254414773803597 0.684457862089655
Lama2 ENSMUSG00000019899 0.297095062262362 0.297095062262362 0.170434860179341 0.255652290269012 0.0741204440774082 0.222361332232225
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Txnrd1 ENSMUSG00000020250 0.399548817627028 0.683948417459205 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Ncoa1 ENSMUSG00000020647 0.78180291566155 0.78180291566155 0.399548817627028 0.599323226440542 0.398829756175299 0.599323226440542
Nos2 ENSMUSG00000020826 0.0417377002086289 0.125213100625887 0.781645261743309 0.781645261743309 0.711650020253571 0.781645261743309
Bdkrb2 ENSMUSG00000021070 0.450794830295117 0.708745765211584 0.708745765211584 0.708745765211584 0.639337105615665 0.708745765211584
Edn1 ENSMUSG00000021367 0.577259514257969 0.577259514257969 0.57466664340579 0.577259514257969 0.346527959006435 0.577259514257969
Dapk1 ENSMUSG00000021559 0.5155648232968 0.7733472349452 0.450794830295118 0.7733472349452 0.926550375688041 0.926550375688041
Il6st ENSMUSG00000021756 0.576973746230334 0.865460619345501 0.926658283600152 0.926658283600152 0.300095920620218 0.865460619345501
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Ifnar1 ENSMUSG00000022967 0.298974794311434 0.448462191467151 0.096147151118103 0.288441453354309 0.576973746230334 0.576973746230334
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Epas1 ENSMUSG00000024140 0.514934023620345 0.514934023620345 0.299349060054895 0.51304020805012 0.342026805366747 0.51304020805012
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Casp7 ENSMUSG00000025076 0.395196379647461 0.395196379647461 0.213307944885796 0.395196379647461 0.395196379647461 0.395196379647461
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Abl1 ENSMUSG00000026842 0.643359829732651 0.853801250889739 0.300095920620218 0.853801250889739 0.853801250889739 0.853801250889739
Notch1 ENSMUSG00000026923 0.782117202022501 0.782117202022501 0.346527959006435 0.521459286037555 0.347639524025037 0.521459286037555
Dll4 ENSMUSG00000027314 0.640861491578951 0.961292237368426 0.640861491578951 0.961292237368426 1 1
Mecom ENSMUSG00000027684 0.179597906187076 0.538793718561228 0.71082910328023 0.71082910328023 0.643112334413352 0.71082910328023
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Fadd ENSMUSG00000031077 0.710208797518812 0.926333123228344 0.0588232673880149 0.176469802164045 0.926333123228344 0.926333123228344
Ednra ENSMUSG00000031616 0.5155648232968 0.7733472349452 0.853480389728993 0.853480389728993 0.256271555563966 0.768814666691898
Mmp2 ENSMUSG00000031740 0.248769231421035 0.373153847131552 0.853480389728993 0.853480389728993 0.0318737159052625 0.0956211477157874
Ets1 ENSMUSG00000032035 0.0449262652924809 0.134778795877443 1 1 0.180293335960318 0.270440003940477
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Gnai2 ENSMUSG00000032562 0.852940894477647 0.852940894477647 0.643359829732651 0.852940894477647 0.180293335960318 0.540880007880955
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Notch3 ENSMUSG00000038146 0.643853282854191 0.643853282854191 0.148115998140416 0.382180685423408 0.254787123615605 0.382180685423408
Gstp2 ENSMUSG00000038155 0.344663224299303 0.8650311008608 1 1 0.576687400573867 0.8650311008608
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Ccdc6 ENSMUSG00000048701 0.00695468356472021 0.0208640506941606 0.575824878403157 0.863737317604735 0.924872384323463 0.924872384323463
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Lamb2 ENSMUSG00000052911 0.399548817627028 0.599323226440542 1 1 0.180293335960318 0.540880007880955
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Max ENSMUSG00000059436 0.0741204440774082 0.222361332232225 0.254787123615605 0.346899083932133 0.346899083932133 0.346899083932133
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626

Lysosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gm2a ENSMUSG00000000594 0.853801250889739 0.853801250889739 0.711034989117171 0.853801250889739 0.711854160331342 0.853801250889739
Man2b1 ENSMUSG00000005142 0.0447373296833728 0.134211989050119 0.212808218863155 0.319212328294733 0.392985378348026 0.392985378348026
Hyal2 ENSMUSG00000010047 0.926658283600152 0.926658283600152 0.853694531487825 0.926658283600152 0.399548817627028 0.926658283600152
Galns ENSMUSG00000015027 0.781960228679124 1 0.096147151118103 0.288441453354309 1 1
Ctsz ENSMUSG00000016256 0.329176790045262 0.493765185067894 0.774176834800231 0.774176834800231 0.288654423610209 0.493765185067894
Ap3d1 ENSMUSG00000020198 0.781170242226513 0.852832278580641 0.852832278580641 0.852832278580641 0.300095920620218 0.852832278580641
Ap3b1 ENSMUSG00000021686 0.297095062262363 0.445642593393544 0.17610058307789 0.445642593393544 0.578396848531894 0.578396848531894
Litaf ENSMUSG00000022500 0.45596561163947 0.683948417459205 0.0741204440774083 0.222361332232225 0.711650020253571 0.711650020253571
Arsa ENSMUSG00000022620 0.711034989117171 1 1 1 0.577259514257969 1
Npc1 ENSMUSG00000024413 0.853372965654504 0.853372965654504 0.180293335960318 0.519791938509652 0.346527959006435 0.519791938509652
Ap3s1 ENSMUSG00000024480 1 1 0.347639524025037 0.770497594023414 0.513665062682276 0.770497594023414
Hexa ENSMUSG00000025232 0.926441990075769 0.926441990075769 0.213307944885796 0.321055621146488 0.214037080764326 0.321055621146488
Abca2 ENSMUSG00000026944 0.146141353215795 0.269918683616058 0.179945789077372 0.269918683616058 0.853694531487825 0.853694531487825
Clta ENSMUSG00000028478 1 1 0.853372965654504 1 0.782117202022501 1
Laptm5 ENSMUSG00000028581 0.78180291566155 0.853907737111068 0.853907737111068 0.853907737111068 0.640861491578951 0.853907737111068
Lamp1 ENSMUSG00000031447 0.851954599472143 0.851954599472143 0.451840588205062 0.677760882307593 0.179945789077372 0.539837367232115
Aga ENSMUSG00000031521 0.454600801949285 0.681901202923927 0.711854160331342 0.711854160331342 0.0441715176243983 0.132514552873195
Asah1 ENSMUSG00000031591 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513 0.398108175780842 0.597162263671263
Ap1g1 ENSMUSG00000031731 0.0150443553124284 0.0451330659372852 0.577259514257969 0.710208797518812 0.710208797518812 0.710208797518812
Gga1 ENSMUSG00000033128 0.778911768167544 0.780851835278818 0.780851835278818 0.780851835278818 0.148115998140416 0.444347994421247
Atp6v0a2 ENSMUSG00000038023 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041 0.78180291566155 0.926550375688041
Atp6v0a4 ENSMUSG00000038600 0.45596561163947 0.683948417459205 0.710001140920767 0.710001140920767 0.252920381501207 0.683948417459205
Arsb ENSMUSG00000042082 0.514934023620344 0.711240436189781 0.348008842235184 0.711240436189781 0.711240436189781 0.711240436189781
Cltb ENSMUSG00000047547 0.852832278580641 0.92589277149125 0.92589277149125 0.92589277149125 0.397384062266614 0.92589277149125
Ap3s2 ENSMUSG00000063801 0.92622377157404 0.92622377157404 0.711854160331342 0.92622377157404 0.297848640636702 0.893545921910107
Entpd4 ENSMUSG00000095463 0.0947558980989551 0.284267694296865 0.573498913947369 0.573498913947369 0.347639524025037 0.521459286037555

Breast cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Jag2 ENSMUSG00000002799 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.0756145297453649 0.226843589236095
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Ncoa1 ENSMUSG00000020647 0.78180291566155 0.78180291566155 0.399548817627028 0.599323226440542 0.398829756175299 0.599323226440542
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Notch1 ENSMUSG00000026923 0.782117202022501 0.782117202022501 0.346527959006435 0.521459286037555 0.347639524025037 0.521459286037555
Dll4 ENSMUSG00000027314 0.640861491578951 0.961292237368426 0.640861491578951 0.961292237368426 1 1
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Notch3 ENSMUSG00000038146 0.643853282854191 0.643853282854191 0.148115998140416 0.382180685423408 0.254787123615605 0.382180685423408
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

T cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.710416009055326 0.710416009055326 0.180293335960318 0.270440003940477 0.177153312234059 0.270440003940477
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Dlg1 ENSMUSG00000022770 0.781170242226513 1 1 1 0.148115998140415 0.444347994421246
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Icos ENSMUSG00000026009 0.643112334413352 0.643112334413352 0.17855224077719 0.535656722331571 0.575824878403157 0.643112334413352
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Bcl10 ENSMUSG00000028191 0.925444427431699 0.925444427431699 0.25141795904251 0.754253877127531 0.5155648232968 0.7733472349452
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Card11 ENSMUSG00000036526 0.707899741868332 1 0.0955908182073974 0.286772454622192 1 1
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Cd8a ENSMUSG00000053977 0.708111938090394 0.853157406788312 0.50716883916608 0.853157406788312 0.853157406788312 0.853157406788312
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Colorectal cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Bbc3 ENSMUSG00000002083 0.21549027811633 0.21549027811633 0.146141353215796 0.21549027811633 0.177153312234059 0.21549027811633
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Birc5 ENSMUSG00000017716 0.852504981253341 0.852504981253341 0.456305241393103 0.684457862089655 0.254414773803597 0.684457862089655
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Renal cell carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tfe3 ENSMUSG00000000134 0.711650020253571 0.78180291566155 0.781170242226513 0.78180291566155 0.78180291566155 0.78180291566155
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Prcc ENSMUSG00000004895 0.853480389728993 0.853480389728993 0.514934023620345 0.853480389728993 0.711034989117171 0.853480389728993
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Epas1 ENSMUSG00000024140 0.514934023620345 0.514934023620345 0.299349060054895 0.51304020805012 0.342026805366747 0.51304020805012
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Ets1 ENSMUSG00000032035 0.0449262652924809 0.134778795877443 1 1 0.180293335960318 0.270440003940477
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Sphingolipid signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.451840588205062 0.640355507848752 0.640355507848752 0.640355507848752 0.254787123615605 0.640355507848752
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Gab2 ENSMUSG00000004508 0.570836132666921 0.570836132666921 0.253294730253594 0.438788713627291 0.29252580908486 0.438788713627291
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Bdkrb2 ENSMUSG00000021070 0.450794830295117 0.708745765211584 0.708745765211584 0.708745765211584 0.639337105615665 0.708745765211584
Degs2 ENSMUSG00000021263 0.0592616003460511 0.177784801038153 0.578113371816017 0.578113371816017 0.21549027811633 0.323235417174495
Ppp2r5b ENSMUSG00000024777 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Asah1 ENSMUSG00000031591 0.0436072256433733 0.13082167693012 0.781170242226513 0.781170242226513 0.398108175780842 0.597162263671263
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Gnai2 ENSMUSG00000032562 0.852940894477647 0.852940894477647 0.643359829732651 0.852940894477647 0.180293335960318 0.540880007880955
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Acer2 ENSMUSG00000038007 0.782117202022501 0.782117202022501 0.711650020253571 0.782117202022501 0.347639524025037 0.782117202022501
S1pr4 ENSMUSG00000044199 0.398829756175299 0.598244634262948 0.853157406788312 0.853157406788312 0.146141353215796 0.438424059647387
S1pr5 ENSMUSG00000045087 0.148772260628989 0.446316781886968 0.710001140920767 0.710001140920767 0.643359829732651 0.710001140920767
S1pr1 ENSMUSG00000045092 0.514934023620345 0.514934023620345 0.209636747299872 0.314455120949809 0.180293335960318 0.314455120949809
Sgms2 ENSMUSG00000050931 0.329576740674783 0.329576740674783 0.119631084167591 0.251893523158358 0.167929015438905 0.251893523158358
Sphk2 ENSMUSG00000057342 1 1 0.344663224299303 0.520348625898199 0.346899083932133 0.520348625898199
Ppp2r5d ENSMUSG00000059409 0.300095920620218 0.849890346946107 0.566593564630738 0.849890346946107 0.851732715229127 0.851732715229127
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Rap1 signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Sipa1l2 ENSMUSG00000001995 0.779888212132595 0.779888212132595 0.255901190956604 0.767703572869811 0.575824878403157 0.779888212132595
Efna2 ENSMUSG00000003070 0.852940894477647 0.852940894477647 0.0158546704257246 0.0475640112771739 0.173632433887832 0.260448650831748
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Tek ENSMUSG00000006386 0.0241933715424143 0.0725801146272428 1 1 0.120850531362929 0.181275797044394
Epha2 ENSMUSG00000006445 1 1 0.17750354896016 0.53251064688048 0.78148726569172 1
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Pfn1 ENSMUSG00000018293 0.926333123228344 0.926441990075769 0.926441990075769 0.926441990075769 0.781170242226513 0.926441990075769
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Map2k6 ENSMUSG00000020623 1 1 0.712057867818062 1 1 1
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Arap3 ENSMUSG00000024451 0.0958690133561598 0.144637845807821 0.711854160331342 0.711854160331342 0.0964252305385472 0.144637845807821
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Efna1 ENSMUSG00000027954 0.148115998140416 0.222173997210623 1 1 0.09586901335616 0.222173997210623
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Flt1 ENSMUSG00000029648 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.148772260628989 0.446316781886968
Sipa1l3 ENSMUSG00000030583 0.640355507848752 0.711240436189781 0.148115998140416 0.444347994421247 0.711240436189781 0.711240436189781
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Gnai2 ENSMUSG00000032562 0.852940894477647 0.852940894477647 0.643359829732651 0.852940894477647 0.180293335960318 0.540880007880955
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Pard6b ENSMUSG00000044641 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Tln2 ENSMUSG00000052698 0.577259514257968 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Sipa1 ENSMUSG00000056917 0.454942951775342 0.578396848531894 0.454600801949285 0.578396848531894 0.578396848531894 0.578396848531894
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

B cell receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Pik3ap1 ENSMUSG00000025017 0.77858338846904 0.77858338846904 0.711240436189781 0.77858338846904 0.342026805366747 0.77858338846904
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Bcl10 ENSMUSG00000028191 0.925444427431699 0.925444427431699 0.25141795904251 0.754253877127531 0.5155648232968 0.7733472349452
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Card11 ENSMUSG00000036526 0.707899741868332 1 0.0955908182073974 0.286772454622192 1 1
Cd81 ENSMUSG00000037706 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152 0.297848640636702 0.893545921910107
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Fc gamma R-mediated phagocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Gab2 ENSMUSG00000004508 0.570836132666921 0.570836132666921 0.253294730253594 0.438788713627291 0.29252580908486 0.438788713627291
Myo10 ENSMUSG00000022272 0.780851835278817 0.780851835278817 0.0575107614292585 0.172532284287776 0.454600801949285 0.681901202923927
Bin1 ENSMUSG00000024381 0.578113371816017 0.578113371816017 0.144820068500793 0.265729968351089 0.177153312234059 0.265729968351089
Ppap2b ENSMUSG00000028517 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155 0.345037391052887 0.78180291566155
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Pla2g6 ENSMUSG00000042632 0.254787123615605 0.254787123615605 0.254414773803597 0.254787123615605 0.254414773803597 0.254787123615605
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Marcksl1 ENSMUSG00000047945 0.344663224299303 0.516994836448954 0.295581119060361 0.516994836448954 0.709375484777034 0.709375484777034
Sphk2 ENSMUSG00000057342 1 1 0.344663224299303 0.520348625898199 0.346899083932133 0.520348625898199
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Protein processing in endoplasmic reticulum

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ssr4 ENSMUSG00000002014 0.576973746230334 0.643853282854191 0.5155648232968 0.643853282854191 0.643853282854191 0.643853282854191
Prkcsh ENSMUSG00000003402 0.635703516568382 0.850151080737202 0.850151080737202 0.850151080737202 0.297848640636702 0.850151080737202
Rad23a ENSMUSG00000003813 0.926441990075769 0.926441990075769 0.34837756124189 0.772401035430517 0.514934023620345 0.772401035430517
Calr ENSMUSG00000003814 0.710416009055326 0.781170242226513 0.643853282854191 0.781170242226513 0.781170242226513 0.781170242226513
Ubqln1 ENSMUSG00000005312 0.513026869856283 0.769540304784424 0.926003599371282 0.926003599371282 0.342405296020881 0.769540304784424
Atf6b ENSMUSG00000015461 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.347639524025037 0.642864324224729
Dnajb12 ENSMUSG00000020109 0.578113371816017 0.578113371816017 0.179945789077372 0.539837367232115 0.513026869856283 0.578113371816017
Rnf185 ENSMUSG00000020448 0.398108175780842 0.771451162979439 0.853801250889739 0.853801250889739 0.514300775319626 0.771451162979439
Ube2j2 ENSMUSG00000023286 0.399548817627028 0.853801250889739 0.853801250889739 0.853801250889739 0.78180291566155 0.853801250889739
Syvn1 ENSMUSG00000024807 0.058823267388015 0.176469802164045 0.216214347033995 0.324321520550992 0.712057867818062 0.712057867818062
P4hb ENSMUSG00000025130 0.78148726569172 0.78148726569172 0.575824878403157 0.78148726569172 0.346527959006435 0.78148726569172
Ddit3 ENSMUSG00000025408 0.179945789077372 0.269918683616058 0.395196379647461 0.395196379647461 0.0953125666339398 0.269918683616058
Sec61a2 ENSMUSG00000025816 0.711034989117171 0.853480389728993 0.45596561163947 0.853480389728993 0.853480389728993 0.853480389728993
Dnajb2 ENSMUSG00000026203 0.641867098978198 0.92589277149125 0.92589277149125 0.92589277149125 0.180293335960318 0.540880007880955
Capn2 ENSMUSG00000026509 0.85117361048289 0.85117361048289 0.0763619660358786 0.229085898107636 0.513665062682276 0.770497594023414
Rpn2 ENSMUSG00000027642 0.78180291566155 0.78180291566155 0.513665062682276 0.770497594023414 0.453225835454266 0.770497594023414
Eif2ak3 ENSMUSG00000031668 0.299349060054895 0.683438032073173 0.455625354715449 0.683438032073173 0.926550375688041 0.926550375688041
Amfr ENSMUSG00000031751 0.17750354896016 0.447899954960299 0.45596561163947 0.45596561163947 0.298599969973533 0.447899954960299
Uggt1 ENSMUSG00000037470 0.0936419271039906 0.280925781311972 0.92622377157404 0.92622377157404 0.514934023620345 0.772401035430517
Ppp1r15a ENSMUSG00000040435 0.573498913947369 0.860248370921054 0.348008842235184 0.860248370921054 0.926441990075769 0.926441990075769
Os9 ENSMUSG00000040462 0.926333123228344 0.926333123228344 0.576973746230334 0.865460619345501 0.299349060054895 0.865460619345501
Uggt2 ENSMUSG00000042104 0.643853282854191 0.78180291566155 0.78180291566155 0.78180291566155 0.711854160331342 0.78180291566155
Ckap4 ENSMUSG00000046841 0.779888212132595 0.779888212132595 0.454942951775342 0.682414427663012 0.211110344399808 0.633331033199424
Ubqln2 ENSMUSG00000050148 0.78180291566155 0.92622377157404 0.92622377157404 0.92622377157404 0.577259514257969 0.92622377157404
Ubxn8 ENSMUSG00000052906 0.454600801949285 0.681901202923927 1 1 0.348008842235184 0.681901202923927
Hspa2 ENSMUSG00000059970 0.78148726569172 0.78148726569172 0.5155648232968 0.7733472349452 0.514934023620344 0.7733472349452
Ubxn1 ENSMUSG00000071655 0.576112968612194 0.576112968612194 0.117185073436597 0.351555220309791 0.454600801949285 0.576112968612194
Ube2d2a ENSMUSG00000091896 0.926003599371282 0.926003599371282 0.295581119060361 0.886743357181082 0.712057867818062 0.926003599371282
Hspa1a ENSMUSG00000091971 0.255530331334266 0.711650020253571 0.711650020253571 0.711650020253571 0.643359829732651 0.711650020253571

Regulation of actin cytoskeleton

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.451840588205062 0.640355507848752 0.640355507848752 0.640355507848752 0.254787123615605 0.640355507848752
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Pfn1 ENSMUSG00000018293 0.926333123228344 0.926441990075769 0.926441990075769 0.926441990075769 0.781170242226513 0.926441990075769
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Bdkrb2 ENSMUSG00000021070 0.450794830295117 0.708745765211584 0.708745765211584 0.708745765211584 0.639337105615665 0.708745765211584
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Itgb5 ENSMUSG00000022817 0.0236697127745139 0.0648478400701163 0.514934023620344 0.514934023620344 0.0432318933800775 0.0648478400701163
Fgd1 ENSMUSG00000025265 0.298599969973533 0.895799909920599 0.926333123228344 0.926333123228344 0.852940894477647 0.926333123228344
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Pip4k2a ENSMUSG00000026737 0.852175490580835 1 0.398108175780842 1 1 1
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Iqgap3 ENSMUSG00000028068 0.639847384224008 0.639847384224008 0.342783164254397 0.592794569471191 0.395196379647461 0.592794569471191
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Iqgap1 ENSMUSG00000030536 0.575824878403157 0.863737317604735 0.0969812105731562 0.290943631719469 1 1
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Itgax ENSMUSG00000030789 0.120545895661628 0.180818843492441 0.926496242814507 0.926496242814507 0.0447373296833729 0.134211989050119
Msn ENSMUSG00000031207 0.511742979522636 0.767614469283954 0.148772260628989 0.446316781886967 0.926333123228344 0.926333123228344
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Itga9 ENSMUSG00000039115 0.397384062266614 0.682414427663012 0.926550375688041 0.926550375688041 0.454942951775342 0.682414427663012
Ppp1ca ENSMUSG00000040385 0.180293335960318 0.540880007880954 0.852175490580835 1 1 1
Ssh1 ENSMUSG00000042121 0.295581119060361 0.443371678590541 0.211844580334808 0.443371678590541 0.576973746230334 0.576973746230334
Itga1 ENSMUSG00000042284 0.926550375688041 0.926550375688041 0.395928178642446 0.593892267963669 0.299349060054895 0.593892267963669
Tmsb4x ENSMUSG00000049775 0.575824878403157 0.852065168704833 0.347639524025037 0.852065168704833 0.852065168704833 0.852065168704833
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Phospholipase D signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gna12 ENSMUSG00000000149 0.451840588205062 0.640355507848752 0.640355507848752 0.640355507848752 0.254787123615605 0.640355507848752
Agpat3 ENSMUSG00000001211 0.711854160331342 0.712057867818062 0.712057867818062 0.712057867818062 0.254414773803597 0.712057867818062
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Gab2 ENSMUSG00000004508 0.570836132666921 0.570836132666921 0.253294730253594 0.438788713627291 0.29252580908486 0.438788713627291
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Cyth3 ENSMUSG00000018001 0.147458757705094 0.223158390943484 0.148772260628989 0.223158390943484 0.254787123615605 0.254787123615605
Cyth4 ENSMUSG00000018008 0.853372965654504 0.853372965654504 0.252545530864481 0.378818296296722 0.0753654386865988 0.226096316059796
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Agpat2 ENSMUSG00000026922 0.853801250889739 0.853801250889739 0.711034989117171 0.853801250889739 0.640861491578951 0.853801250889739
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Ppap2b ENSMUSG00000028517 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155 0.345037391052887 0.78180291566155
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Sphk2 ENSMUSG00000057342 1 1 0.344663224299303 0.520348625898199 0.346899083932133 0.520348625898199
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Vitamin digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc19a1 ENSMUSG00000001436 0.852504981253341 0.852504981253341 0.643359829732651 0.852504981253341 0.0964252305385472 0.289275691615642
Tcn2 ENSMUSG00000020432 0.576973746230334 0.782117202022501 0.782117202022501 0.782117202022501 0.575824878403157 0.782117202022501
Slc46a1 ENSMUSG00000020829 0.710416009055326 0.926550375688041 0.926550375688041 0.926550375688041 0.514934023620344 0.926550375688041
Btd ENSMUSG00000021900 0.180293335960318 0.270440003940477 0.146800541856249 0.270440003940477 0.577259514257969 0.577259514257969
Cubn ENSMUSG00000026726 0.643853282854191 0.643853282854191 0.119631084167592 0.358893252502775 0.57466664340579 0.643853282854191
Slc52a3 ENSMUSG00000027463 0.0169973161381212 0.0509919484143637 0.781645261743309 0.781645261743309 0.14844425178295 0.222666377674426
Mmachc ENSMUSG00000028690 0.853372965654504 1 1 1 0.926003599371282 1
Scarb1 ENSMUSG00000037936 0.853694531487825 0.853694531487825 0.711854160331342 0.853694531487825 0.45596561163947 0.853694531487825

Hepatocellular carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Smarcb1 ENSMUSG00000000902 0.298599969973533 0.681901202923927 1 1 0.454600801949285 0.681901202923927
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Txnrd1 ENSMUSG00000020250 0.399548817627028 0.683948417459205 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Smarcc2 ENSMUSG00000025369 0.78180291566155 0.78180291566155 0.148772260628989 0.446316781886968 0.573791743469336 0.78180291566155
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Smarca4 ENSMUSG00000032187 0.708534948098331 0.708534948098331 0.347639524025037 0.708534948098331 0.576112968612194 0.708534948098331
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Gstp2 ENSMUSG00000038155 0.344663224299303 0.8650311008608 1 1 0.576687400573867 0.8650311008608
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Arid1b ENSMUSG00000069729 0.853372965654504 0.926550375688041 0.346899083932133 0.926550375688041 0.926550375688041 0.926550375688041

Gastric cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Jup ENSMUSG00000001552 0.853372965654504 1 0.300095920620218 0.900287761860653 1 1
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Abcb1a ENSMUSG00000040584 0.216214347033995 0.324321520550992 0.781170242226513 0.781170242226513 0.148115998140416 0.324321520550992
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Choline metabolism in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Pcyt1a ENSMUSG00000005615 0.576973746230334 0.865460619345501 0.92622377157404 0.92622377157404 0.514300775319626 0.865460619345501
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Chkb ENSMUSG00000022617 0.452880492349546 0.769540304784424 0.78180291566155 0.78180291566155 0.513026869856283 0.769540304784424
Chka ENSMUSG00000024843 0.711240436189781 0.781170242226513 0.399548817627028 0.781170242226513 0.781170242226513 0.781170242226513
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Ppap2b ENSMUSG00000028517 0.78180291566155 0.78180291566155 0.577259514257969 0.78180291566155 0.345037391052887 0.78180291566155
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Pcyt1b ENSMUSG00000035246 0.926658283600152 0.926658283600152 0.255901190956604 0.599323226440542 0.399548817627028 0.599323226440542
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Wnt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Tle1 ENSMUSG00000008305 0.643359829732651 0.78148726569172 0.780851835278817 0.78148726569172 0.78148726569172 0.78148726569172
Psen1 ENSMUSG00000019969 0.50716883916608 0.707899741868332 0.707899741868332 0.707899741868332 0.453570536021945 0.707899741868332
Ror2 ENSMUSG00000021464 0.392243127063687 0.588364690595531 0.0947558980989551 0.284267694296865 0.710208797518812 0.710208797518812
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Nfatc4 ENSMUSG00000023411 1 1 0.00376384688812124 0.0112915406643637 0.216214347033995 0.324321520550992
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Tle4 ENSMUSG00000024642 0.926658283600152 0.926658283600152 0.299349060054895 0.898047180164686 0.643853282854191 0.926658283600152
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Sox17 ENSMUSG00000025902 0.576687400573867 0.576973746230334 0.576973746230334 0.576973746230334 0.145811394942709 0.437434184828128
Vangl2 ENSMUSG00000026556 0.62976545519988 0.62976545519988 0.447621891168214 0.62976545519988 0.0306217702495172 0.0918653107485517
Ctnnbip1 ENSMUSG00000028988 0.926658283600152 0.926658283600152 0.514934023620344 0.772401035430517 0.299349060054895 0.772401035430517
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Sfrp1 ENSMUSG00000031548 0.926658283600152 0.926658283600152 0.0756145297453649 0.220200812784373 0.146800541856249 0.220200812784373
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Siah1b ENSMUSG00000040749 0.121155015244363 0.363465045733089 0.709375484777034 0.780851835278818 0.780851835278818 0.780851835278818
Znrf3 ENSMUSG00000041961 0.926003599371281 0.926003599371281 0.173632433887832 0.520897301663497 0.853480389728993 0.926003599371281
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993

Chronic myeloid leukemia

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Gab2 ENSMUSG00000004508 0.570836132666921 0.570836132666921 0.253294730253594 0.438788713627291 0.29252580908486 0.438788713627291
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Abl1 ENSMUSG00000026842 0.643359829732651 0.853801250889739 0.300095920620218 0.853801250889739 0.853801250889739 0.853801250889739
Mecom ENSMUSG00000027684 0.179597906187076 0.538793718561228 0.71082910328023 0.71082910328023 0.643112334413352 0.71082910328023
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

ErbB signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Abl1 ENSMUSG00000026842 0.643359829732651 0.853801250889739 0.300095920620218 0.853801250889739 0.853801250889739 0.853801250889739
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Endocrine resistance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Jag2 ENSMUSG00000002799 0.853694531487825 0.853694531487825 0.78180291566155 0.853694531487825 0.0756145297453649 0.226843589236095
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Med1 ENSMUSG00000018160 0.575536202757516 0.863304304136274 0.299349060054896 0.863304304136274 0.926550375688041 0.926550375688041
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Notch1 ENSMUSG00000026923 0.782117202022501 0.782117202022501 0.346527959006435 0.521459286037555 0.347639524025037 0.521459286037555
Dll4 ENSMUSG00000027314 0.640861491578951 0.961292237368426 0.640861491578951 0.961292237368426 1 1
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Mmp2 ENSMUSG00000031740 0.248769231421035 0.373153847131552 0.853480389728993 0.853480389728993 0.0318737159052625 0.0956211477157874
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Notch3 ENSMUSG00000038146 0.643853282854191 0.643853282854191 0.148115998140416 0.382180685423408 0.254787123615605 0.382180685423408
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

AGE-RAGE signaling pathway in diabetic complications

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Stat3 ENSMUSG00000004040 0.342026805366747 0.51304020805012 0.0953125666339397 0.285937699901819 0.853801250889739 0.853801250889739
Edn1 ENSMUSG00000021367 0.577259514257969 0.577259514257969 0.57466664340579 0.577259514257969 0.346527959006435 0.577259514257969
Smad4 ENSMUSG00000024515 0.450444934184774 0.675667401277161 0.926003599371282 0.926003599371282 0.295581119060361 0.675667401277161
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Mmp2 ENSMUSG00000031740 0.248769231421035 0.373153847131552 0.853480389728993 0.853480389728993 0.0318737159052625 0.0956211477157874
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626

mTOR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Stk11 ENSMUSG00000003068 0.147458757705094 0.148115998140416 0.0969812105731562 0.148115998140416 0.148115998140416 0.148115998140416
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Akt1s1 ENSMUSG00000011096 0.177853449259986 0.533560347779958 0.926003599371282 0.926003599371282 0.578396848531894 0.867595272797842
Gatsl3 ENSMUSG00000020424 0.5155648232968 0.5155648232968 0.398108175780842 0.5155648232968 0.399548817627028 0.5155648232968
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Mlst8 ENSMUSG00000024142 0.148115998140415 0.444347994421246 0.642864324224729 0.642864324224729 0.399548817627028 0.599323226440542
Lrp5 ENSMUSG00000024913 0.643853282854191 0.643853282854191 0.45596561163947 0.643853282854191 0.454600801949285 0.643853282854191
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Rptor ENSMUSG00000025583 0.926333123228344 0.926333123228344 0.514934023620344 0.772401035430517 0.346527959006435 0.772401035430517
Tti1 ENSMUSG00000027650 0.300095920620218 0.393724994268831 0.393724994268831 0.393724994268831 0.044926265292481 0.134778795877443
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Sesn2 ENSMUSG00000028893 0.5155648232968 0.5155648232968 0.179945789077372 0.269918683616058 0.147458757705094 0.269918683616058
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Depdc5 ENSMUSG00000037426 0.455625354715449 0.683438032073174 0.926003599371282 0.926003599371282 0.115037265385284 0.345111796155853
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Eif4b ENSMUSG00000058655 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Human papillomavirus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Lama5 ENSMUSG00000015647 0.643853282854191 0.643853282854191 0.576973746230334 0.643853282854191 0.297095062262362 0.643853282854191
Lama2 ENSMUSG00000019899 0.297095062262362 0.297095062262362 0.170434860179341 0.255652290269012 0.0741204440774082 0.222361332232225
Psen1 ENSMUSG00000019969 0.50716883916608 0.707899741868332 0.707899741868332 0.707899741868332 0.453570536021945 0.707899741868332
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Slc9a3r1 ENSMUSG00000020733 0.400265374208515 0.600398061312773 0.0763619660358786 0.229085898107636 0.926333123228344 0.926333123228344
Fzd6 ENSMUSG00000022297 0.044737329683373 0.134211989050119 0.642366752097095 0.710001140920767 0.710001140920767 0.710001140920767
Dlg1 ENSMUSG00000022770 0.781170242226513 1 1 1 0.148115998140415 0.444347994421246
Itgb5 ENSMUSG00000022817 0.0236697127745139 0.0648478400701163 0.514934023620344 0.514934023620344 0.0432318933800775 0.0648478400701163
Ifnar1 ENSMUSG00000022967 0.298974794311434 0.448462191467151 0.096147151118103 0.288441453354309 0.576973746230334 0.576973746230334
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Ppp2r5b ENSMUSG00000024777 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Notch1 ENSMUSG00000026923 0.782117202022501 0.782117202022501 0.346527959006435 0.521459286037555 0.347639524025037 0.521459286037555
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Lfng ENSMUSG00000029570 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.92622377157404 0.92622377157404
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Fadd ENSMUSG00000031077 0.710208797518812 0.926333123228344 0.0588232673880149 0.176469802164045 0.926333123228344 0.926333123228344
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Tubg1 ENSMUSG00000035198 0.576973746230334 0.709375484777034 0.709375484777034 0.709375484777034 0.348008842235184 0.709375484777034
Fzd8 ENSMUSG00000036904 0.449038745266226 0.449038745266226 0.298974794311434 0.448462191467151 0.0967032506702098 0.290109752010629
Atp6v0a2 ENSMUSG00000038023 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041 0.78180291566155 0.926550375688041
Notch3 ENSMUSG00000038146 0.643853282854191 0.643853282854191 0.148115998140416 0.382180685423408 0.254787123615605 0.382180685423408
Atp6v0a4 ENSMUSG00000038600 0.45596561163947 0.683948417459205 0.710001140920767 0.710001140920767 0.252920381501207 0.683948417459205
Creb3l2 ENSMUSG00000038648 0.513665062682276 0.770497594023414 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501
Chad ENSMUSG00000039084 0.850265736951714 0.850265736951714 0.705098431925329 0.850265736951714 0.705098431925329 0.850265736951714
Itga9 ENSMUSG00000039115 0.397384062266614 0.682414427663012 0.926550375688041 0.926550375688041 0.454942951775342 0.682414427663012
Itga1 ENSMUSG00000042284 0.926550375688041 0.926550375688041 0.395928178642446 0.593892267963669 0.299349060054895 0.593892267963669
Pard6b ENSMUSG00000044641 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Fzd1 ENSMUSG00000044674 0.511097249598474 0.766645874397711 0.926441990075769 0.926441990075769 0.255530331334266 0.766590994002797
Fzd9 ENSMUSG00000049551 0.455625354715448 0.683438032073173 0.781960228679124 0.781960228679124 0.397021051130447 0.683438032073173
Fzd4 ENSMUSG00000049791 0.255530331334266 0.766590994002797 0.5155648232968 0.7733472349452 0.926658283600152 0.926658283600152
Fzd2 ENSMUSG00000050288 0.782117202022501 1 0.347639524025037 1 1 1
Dlg2 ENSMUSG00000052572 0.926550375688041 0.926550375688041 0.853907737111068 0.926550375688041 0.577829325134931 0.926550375688041
Lamb2 ENSMUSG00000052911 0.399548817627028 0.599323226440542 1 1 0.180293335960318 0.540880007880955
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Ppp2r5d ENSMUSG00000059409 0.300095920620218 0.849890346946107 0.566593564630738 0.849890346946107 0.851732715229127 0.851732715229127
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Maml3 ENSMUSG00000061143 0.343537039781257 0.515305559671886 0.0315593554855452 0.0946780664566357 0.643359829732651 0.643359829732651
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626
H2-D1 ENSMUSG00000073411 0.453225835454266 0.453225835454266 0.400265374208515 0.453225835454266 0.21549027811633 0.453225835454266

Salmonella infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Snx9 ENSMUSG00000002365 0.171147788308685 0.171147788308685 0.0758636487647836 0.113795473147175 0.0564200190955604 0.113795473147175
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Dynll1 ENSMUSG00000009013 0.926550375688041 0.926550375688041 0.453570536021945 0.680355804032917 0.173632433887832 0.520897301663497
Cyth3 ENSMUSG00000018001 0.147458757705094 0.223158390943484 0.148772260628989 0.223158390943484 0.254787123615605 0.254787123615605
Cyth4 ENSMUSG00000018008 0.853372965654504 0.853372965654504 0.252545530864481 0.378818296296722 0.0753654386865988 0.226096316059796
Pfn1 ENSMUSG00000018293 0.926333123228344 0.926441990075769 0.926441990075769 0.926441990075769 0.781170242226513 0.926441990075769
Map2k6 ENSMUSG00000020623 1 1 0.712057867818062 1 1 1
Exoc7 ENSMUSG00000020792 0.640861491578951 0.640861491578951 0.57466664340579 0.640861491578951 0.345037391052887 0.640861491578951
Klc1 ENSMUSG00000021288 0.781170242226513 0.781170242226513 0.711650020253571 0.781170242226513 0.454942951775341 0.781170242226513
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Casp7 ENSMUSG00000025076 0.395196379647461 0.395196379647461 0.213307944885796 0.395196379647461 0.395196379647461 0.395196379647461
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Podxl ENSMUSG00000025608 0.214764523938594 0.322146785907891 0.643853282854191 0.643853282854191 0.120850531362929 0.322146785907891
Arl8a ENSMUSG00000026426 0.711854160331342 0.711854160331342 0.455625354715449 0.683438032073173 0.400265374208515 0.683438032073173
Acbd3 ENSMUSG00000026499 0.0761127945805735 0.228338383741721 0.847801182751652 0.847801182751652 0.176802739037618 0.265204108556428
Dync1i2 ENSMUSG00000027012 0.710208797518812 0.710208797518812 0.216214347033995 0.324321520550992 0.21549027811633 0.324321520550992
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Dync1i1 ENSMUSG00000029757 0.297848640636702 0.446772960955053 0.288654423610209 0.446772960955053 0.851954599472143 0.851954599472143
Fadd ENSMUSG00000031077 0.710208797518812 0.926333123228344 0.0588232673880149 0.176469802164045 0.926333123228344 0.926333123228344
Dctn1 ENSMUSG00000031865 0.852504981253341 0.852504981253341 0.578396848531894 0.852504981253341 0.641867098978198 0.852504981253341
Fbxo22 ENSMUSG00000032309 0.0936419271039908 0.21723010275119 0.144820068500793 0.21723010275119 0.578113371816017 0.578113371816017
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Plekhm1 ENSMUSG00000034247 0.144820068500793 0.43446020550238 0.298599969973533 0.447899954960299 0.852940894477647 0.852940894477647
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Elmo1 ENSMUSG00000041112 0.779888212132595 1 0.852065168704833 1 1 1
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Tlr9 ENSMUSG00000045322 0.511742979522635 0.767614469283952 0.853801250889739 0.853801250889739 0.11810342389482 0.354310271684459
Dynlrb1 ENSMUSG00000047459 0.177153312234059 0.531459936702178 0.711240436189781 0.853801250889739 0.853801250889739 0.853801250889739
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Tuba1a ENSMUSG00000072235 0.255901190956604 0.514934023620345 0.514934023620345 0.514934023620345 0.513665062682276 0.514934023620345
Rab9 ENSMUSG00000079316 0.179945789077372 0.539837367232115 0.513665062682276 0.57466664340579 0.57466664340579 0.57466664340579

PI3K-Akt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Cdkn1b ENSMUSG00000003031 0.711854160331342 0.711854160331342 0.0756145297453646 0.226843589236094 0.454942951775341 0.682414427663012
Stk11 ENSMUSG00000003068 0.147458757705094 0.148115998140416 0.0969812105731562 0.148115998140416 0.148115998140416 0.148115998140416
Efna2 ENSMUSG00000003070 0.852940894477647 0.852940894477647 0.0158546704257246 0.0475640112771739 0.173632433887832 0.260448650831748
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Tek ENSMUSG00000006386 0.0241933715424143 0.0725801146272428 1 1 0.120850531362929 0.181275797044394
Epha2 ENSMUSG00000006445 1 1 0.17750354896016 0.53251064688048 0.78148726569172 1
Atf6b ENSMUSG00000015461 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.347639524025037 0.642864324224729
Lama5 ENSMUSG00000015647 0.643853282854191 0.643853282854191 0.576973746230334 0.643853282854191 0.297095062262362 0.643853282854191
Lama2 ENSMUSG00000019899 0.297095062262362 0.297095062262362 0.170434860179341 0.255652290269012 0.0741204440774082 0.222361332232225
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Ywhae ENSMUSG00000020849 0.576973746230334 0.643359829732651 0.45596561163947 0.643359829732651 0.643359829732651 0.643359829732651
Itgb5 ENSMUSG00000022817 0.0236697127745139 0.0648478400701163 0.514934023620344 0.514934023620344 0.0432318933800775 0.0648478400701163
Ifnar1 ENSMUSG00000022967 0.298974794311434 0.448462191467151 0.096147151118103 0.288441453354309 0.576973746230334 0.576973746230334
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Mlst8 ENSMUSG00000024142 0.148115998140415 0.444347994421246 0.642864324224729 0.642864324224729 0.399548817627028 0.599323226440542
Ppp2r5b ENSMUSG00000024777 0.926550375688041 0.926550375688041 0.643359829732651 0.926550375688041 0.853801250889739 0.926550375688041
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Pik3ap1 ENSMUSG00000025017 0.77858338846904 0.77858338846904 0.711240436189781 0.77858338846904 0.342026805366747 0.77858338846904
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Rptor ENSMUSG00000025583 0.926333123228344 0.926333123228344 0.514934023620344 0.772401035430517 0.346527959006435 0.772401035430517
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Pkn3 ENSMUSG00000026785 0.853372965654504 0.853372965654504 0.642366752097095 0.853372965654504 0.643853282854191 0.853372965654504
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Efna1 ENSMUSG00000027954 0.148115998140416 0.222173997210623 1 1 0.09586901335616 0.222173997210623
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Flt1 ENSMUSG00000029648 0.5155648232968 0.7733472349452 0.781170242226513 0.781170242226513 0.148772260628989 0.446316781886968
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Ccnd3 ENSMUSG00000034165 0.0579478375430677 0.0869217563146015 0.577259514257969 0.577259514257969 0.0441715176243983 0.0869217563146015
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Creb3l2 ENSMUSG00000038648 0.513665062682276 0.770497594023414 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501
Chad ENSMUSG00000039084 0.850265736951714 0.850265736951714 0.705098431925329 0.850265736951714 0.705098431925329 0.850265736951714
Itga9 ENSMUSG00000039115 0.397384062266614 0.682414427663012 0.926550375688041 0.926550375688041 0.454942951775342 0.682414427663012
Itga1 ENSMUSG00000042284 0.926550375688041 0.926550375688041 0.395928178642446 0.593892267963669 0.299349060054895 0.593892267963669
Phlpp1 ENSMUSG00000044340 0.643359829732651 0.780851835278817 0.780851835278817 0.780851835278817 0.297095062262362 0.780851835278817
Lamb2 ENSMUSG00000052911 0.399548817627028 0.599323226440542 1 1 0.180293335960318 0.540880007880955
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Ntrk2 ENSMUSG00000055254 0.576112968612194 0.643853282854191 0.643853282854191 0.643853282854191 0.252920381501207 0.643853282854191
Eif4b ENSMUSG00000058655 0.7802108304765 0.92622377157404 0.92622377157404 0.92622377157404 0.348008842235184 0.92622377157404
Ppp2r5d ENSMUSG00000059409 0.300095920620218 0.849890346946107 0.566593564630738 0.849890346946107 0.851732715229127 0.851732715229127
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Kdr ENSMUSG00000062960 0.044737329683373 0.0671059945250596 0.926333123228344 0.926333123228344 0.0168921052924602 0.0506763158773805
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626

Longevity regulating pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Tsc2 ENSMUSG00000002496 0.7802108304765 0.7802108304765 0.091411676944639 0.274235030833917 0.514300775319626 0.771451162979439
Stk11 ENSMUSG00000003068 0.147458757705094 0.148115998140416 0.0969812105731562 0.148115998140416 0.148115998140416 0.148115998140416
Akt1s1 ENSMUSG00000011096 0.177853449259986 0.533560347779958 0.926003599371282 0.926003599371282 0.578396848531894 0.867595272797842
Atf6b ENSMUSG00000015461 0.454600801949285 0.642864324224729 0.642864324224729 0.642864324224729 0.347639524025037 0.642864324224729
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Rptor ENSMUSG00000025583 0.926333123228344 0.926333123228344 0.514934023620344 0.772401035430517 0.346527959006435 0.772401035430517
Adipor1 ENSMUSG00000026457 0.852940894477647 0.852940894477647 0.643853282854191 0.852940894477647 0.575536202757516 0.852940894477647
Cat ENSMUSG00000027187 0.346899083932133 0.520348625898199 0.576973746230334 0.576973746230334 0.299349060054895 0.520348625898199
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Sesn2 ENSMUSG00000028893 0.5155648232968 0.5155648232968 0.179945789077372 0.269918683616058 0.147458757705094 0.269918683616058
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Sesn3 ENSMUSG00000032009 0.398108175780842 0.597162263671263 0.853694531487825 0.853694531487825 0.398108175780842 0.597162263671263
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Creb3l2 ENSMUSG00000038648 0.513665062682276 0.770497594023414 0.0449262652924809 0.134778795877443 0.782117202022501 0.782117202022501

Bacterial invasion of epithelial cells

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Clta ENSMUSG00000028478 1 1 0.853372965654504 1 0.782117202022501 1
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Cttn ENSMUSG00000031078 0.254787123615605 0.764361370846816 0.926550375688041 0.926550375688041 0.782117202022501 0.926550375688041
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Elmo1 ENSMUSG00000041112 0.779888212132595 1 0.852065168704833 1 1 1
Cltb ENSMUSG00000047547 0.852832278580641 0.92589277149125 0.92589277149125 0.92589277149125 0.397384062266614 0.92589277149125
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833

Selenocompound metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Txnrd1 ENSMUSG00000020250 0.399548817627028 0.683948417459205 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Mtr ENSMUSG00000021311 0.0443599545252853 0.133079863575856 0.255901190956604 0.383851786434906 0.782117202022501 0.782117202022501
Scly ENSMUSG00000026307 0.300095920620218 0.348008842235184 0.180293335960318 0.348008842235184 0.348008842235184 0.348008842235184
Papss1 ENSMUSG00000028032 0.392985378348026 0.589478067522039 0.781170242226513 0.781170242226513 0.213307944885796 0.589478067522039
Mars2 ENSMUSG00000046994 0.300095920620218 0.450143880930327 0.853372965654504 0.853372965654504 0.297848640636702 0.450143880930327
Sephs2 ENSMUSG00000049091 0.50716883916608 0.706616781330066 0.706616781330066 0.706616781330066 0.398829756175299 0.706616781330066

Platelet activation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Adcy4 ENSMUSG00000022220 0.0761127945805736 0.228338383741721 0.782117202022501 0.782117202022501 0.45596561163947 0.683948417459205
Adcy8 ENSMUSG00000022376 0.642366752097095 0.642366752097095 0.638824656785692 0.642366752097095 0.638310022345193 0.642366752097095
Gucy1b3 ENSMUSG00000028005 0.216214347033995 0.449023590082343 0.455625354715449 0.455625354715449 0.299349060054895 0.449023590082343
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Itpr2 ENSMUSG00000030287 0.708534948098331 0.708534948098331 0.640861491578951 0.708534948098331 0.0566379395854604 0.169913818756381
Stim1 ENSMUSG00000030987 0.782117202022501 0.782117202022501 0.711854160331342 0.782117202022501 0.455625354715449 0.782117202022501
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Gnai2 ENSMUSG00000032562 0.852940894477647 0.852940894477647 0.643359829732651 0.852940894477647 0.180293335960318 0.540880007880955
Fgg ENSMUSG00000033860 0.576973746230334 0.852832278580641 0.454942951775341 0.852832278580641 0.852832278580641 0.852832278580641
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Tbxa2r ENSMUSG00000034881 0.453225835454266 0.926496242814507 0.926496242814507 0.926496242814507 0.926496242814507 0.926496242814507
Ppp1ca ENSMUSG00000040385 0.180293335960318 0.540880007880954 0.852175490580835 1 1 1
Itpr3 ENSMUSG00000042644 0.338592117141989 0.507888175712984 0.180293335960318 0.507888175712984 0.710416009055326 0.710416009055326
Orai1 ENSMUSG00000049686 0.211844580334808 0.635533741004424 0.450094379653806 0.641867098978198 0.641867098978198 0.641867098978198
Tln2 ENSMUSG00000052698 0.577259514257968 0.642366752097095 0.642366752097095 0.642366752097095 0.45596561163947 0.642366752097095
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Endocytosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Capza2 ENSMUSG00000015733 0.112265881554681 0.336797644664043 0.853372965654504 0.853372965654504 0.347639524025037 0.521459286037555
Cyth3 ENSMUSG00000018001 0.147458757705094 0.223158390943484 0.148772260628989 0.223158390943484 0.254787123615605 0.254787123615605
Cyth4 ENSMUSG00000018008 0.853372965654504 0.853372965654504 0.252545530864481 0.378818296296722 0.0753654386865988 0.226096316059796
Rab4a ENSMUSG00000019478 0.637274134311157 0.637274134311157 0.505169133438821 0.637274134311157 0.450444934184774 0.637274134311157
Ccdc53 ENSMUSG00000020056 0.853801250889739 0.926658283600152 0.641867098978197 0.926658283600152 0.926658283600152 0.926658283600152
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Rab10 ENSMUSG00000020671 0.454942951775341 0.682414427663012 0.926550375688041 0.926550375688041 0.398108175780842 0.682414427663012
Bin1 ENSMUSG00000024381 0.578113371816017 0.578113371816017 0.144820068500793 0.265729968351089 0.177153312234059 0.265729968351089
Arap3 ENSMUSG00000024451 0.0958690133561598 0.144637845807821 0.711854160331342 0.711854160331342 0.0964252305385472 0.144637845807821
Ehd1 ENSMUSG00000024772 0.7802108304765 0.7802108304765 0.710001140920767 0.7802108304765 0.399548817627028 0.7802108304765
Hgs ENSMUSG00000025793 0.399548817627028 0.514934023620344 0.514934023620344 0.514934023620344 0.346899083932133 0.514934023620344
Snx5 ENSMUSG00000027423 0.926658283600152 0.926658283600152 0.346899083932133 0.867170057724026 0.578113371816017 0.867170057724026
Rab22a ENSMUSG00000027519 0.711854160331342 0.78180291566155 0.78180291566155 0.78180291566155 0.255901190956604 0.767703572869812
Chmp5 ENSMUSG00000028419 0.711034989117171 0.711034989117171 0.450444934184774 0.683438032073173 0.455625354715449 0.683438032073173
Clta ENSMUSG00000028478 1 1 0.853372965654504 1 0.782117202022501 1
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Vps36 ENSMUSG00000031479 0.643853282854191 0.643853282854191 0.216214347033995 0.643853282854191 0.455625354715449 0.643853282854191
Rab11fip1 ENSMUSG00000031488 0.450794830295118 0.676192245442677 0.78180291566155 0.78180291566155 0.0756145297453648 0.226843589236094
Ldlr ENSMUSG00000032193 0.853907737111068 0.926550375688041 0.926550375688041 0.926550375688041 0.256271555563966 0.768814666691898
Tgfbr2 ENSMUSG00000032440 0.781170242226513 0.781170242226513 0.711854160331342 0.781170242226513 0.513026869856283 0.781170242226513
Smap2 ENSMUSG00000032870 0.711854160331342 0.926441990075769 0.926441990075769 0.926441990075769 0.578113371816017 0.926441990075769
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Spg20 ENSMUSG00000036580 0.782117202022501 0.782117202022501 0.711034989117171 0.782117202022501 0.342405296020881 0.782117202022501
Ldlrap1 ENSMUSG00000037295 0.926658283600152 0.926658283600152 0.926658283600152 0.926658283600152 0.0382382535564792 0.114714760669438
Mvb12b ENSMUSG00000038740 0.712057867818062 0.712057867818062 0.5155648232968 0.712057867818062 0.34837756124189 0.712057867818062
Iqsec3 ENSMUSG00000040797 0.18064054691103 0.270960820366546 0.0753654386865988 0.226096316059796 0.395196379647461 0.395196379647461
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Pard6b ENSMUSG00000044641 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Cltb ENSMUSG00000047547 0.852832278580641 0.92589277149125 0.92589277149125 0.92589277149125 0.397384062266614 0.92589277149125
Chmp3 ENSMUSG00000053119 0.853694531487825 0.853694531487825 0.853694531487825 0.853694531487825 0.148115998140416 0.444347994421247
Fgfr3 ENSMUSG00000054252 0.058823267388015 0.176469802164045 0.299349060054895 0.449023590082343 0.576973746230334 0.576973746230334
Agap1 ENSMUSG00000055013 0.853801250889739 0.853801250889739 0.255901190956603 0.76770357286981 0.853372965654504 0.853801250889739
Hspa2 ENSMUSG00000059970 0.78148726569172 0.78148726569172 0.5155648232968 0.7733472349452 0.514934023620344 0.7733472349452
H2-D1 ENSMUSG00000073411 0.453225835454266 0.453225835454266 0.400265374208515 0.453225835454266 0.21549027811633 0.453225835454266
Ehd2 ENSMUSG00000074364 0.92622377157404 0.92622377157404 0.78180291566155 0.92622377157404 0.174692232033629 0.524076696100888
Vps25 ENSMUSG00000078656 0.11810342389482 0.354310271684459 0.577829325134931 0.711034989117171 0.711034989117171 0.711034989117171
Hspa1a ENSMUSG00000091971 0.255530331334266 0.711650020253571 0.711650020253571 0.711650020253571 0.643359829732651 0.711650020253571

Axon guidance

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Efna2 ENSMUSG00000003070 0.852940894477647 0.852940894477647 0.0158546704257246 0.0475640112771739 0.173632433887832 0.260448650831748
Epha2 ENSMUSG00000006445 1 1 0.17750354896016 0.53251064688048 0.78148726569172 1
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Unc5b ENSMUSG00000020099 0.254414773803597 0.521459286037555 0.926550375688041 0.926550375688041 0.347639524025037 0.521459286037555
Sema3g ENSMUSG00000021904 0.576973746230334 0.711650020253571 0.711650020253571 0.711650020253571 0.148444251782951 0.445332755348853
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Nfatc4 ENSMUSG00000023411 1 1 0.00376384688812124 0.0112915406643637 0.216214347033995 0.324321520550992
Abl1 ENSMUSG00000026842 0.643359829732651 0.853801250889739 0.300095920620218 0.853801250889739 0.853801250889739 0.853801250889739
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Efna1 ENSMUSG00000027954 0.148115998140416 0.222173997210623 1 1 0.09586901335616 0.222173997210623
Ephb4 ENSMUSG00000029710 0.397384062266614 0.643853282854191 0.450094379653806 0.643853282854191 0.643853282854191 0.643853282854191
Wnt5b ENSMUSG00000030170 0.643359829732651 0.643359829732651 0.253294730253594 0.379942095380391 0.0969812105731562 0.290943631719469
Pak4 ENSMUSG00000030602 0.170434860179341 0.249907451332337 0.249907451332337 0.249907451332337 0.146800541856249 0.249907451332337
Efnb1 ENSMUSG00000031217 0.455625354715448 0.708534948098331 0.708534948098331 0.708534948098331 0.638824656785692 0.708534948098331
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Gnai2 ENSMUSG00000032562 0.852940894477647 0.852940894477647 0.643359829732651 0.852940894477647 0.180293335960318 0.540880007880955
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Plcg2 ENSMUSG00000034330 0.514934023620344 0.772401035430517 0.852504981253341 0.852504981253341 0.250285839267991 0.750857517803972
Rras ENSMUSG00000038387 0.058823267388015 0.176469802164045 0.850721744111585 0.850721744111585 0.514934023620344 0.772401035430517
Rhod ENSMUSG00000041845 0.577259514257969 0.865889271386954 0.926550375688041 0.926550375688041 0.180293335960318 0.540880007880954
Ssh1 ENSMUSG00000042121 0.295581119060361 0.443371678590541 0.211844580334808 0.443371678590541 0.576973746230334 0.576973746230334
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Pard6b ENSMUSG00000044641 0.78180291566155 0.78180291566155 0.78180291566155 0.78180291566155 0.514934023620345 0.78180291566155
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Pak6 ENSMUSG00000074923 0.346527959006435 0.522013263352776 0.348008842235184 0.522013263352776 0.853801250889739 0.853801250889739

Other types of O-glycan biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Plod3 ENSMUSG00000004846 1 1 0.78180291566155 1 0.21549027811633 0.64647083434899
Pofut2 ENSMUSG00000020260 0.576973746230334 0.576973746230334 0.297095062262363 0.445642593393544 0.146800541856249 0.440401625568746
Galnt15 ENSMUSG00000021903 0.17610058307789 0.178901132102685 0.178901132102685 0.178901132102685 0.0303111090728679 0.0909333272186038
St6gal1 ENSMUSG00000022885 0.853372965654504 0.853372965654504 0.255530331334266 0.766590994002797 0.511097249598474 0.766645874397711
Lfng ENSMUSG00000029570 0.344663224299303 0.516994836448954 0.216214347033995 0.516994836448954 0.92622377157404 0.92622377157404
Galnt18 ENSMUSG00000038296 0.511742979522636 0.853372965654504 0.710416009055326 0.853372965654504 0.853372965654504 0.853372965654504
Galnt12 ENSMUSG00000039774 0.578113371816017 0.578113371816017 0.347639524025037 0.578113371816017 0.5155648232968 0.578113371816017
Xxylt1 ENSMUSG00000047434 0.853694531487825 0.853694531487825 0.343537039781257 0.599323226440542 0.399548817627028 0.599323226440542
B4galt3 ENSMUSG00000052423 0.853372965654504 0.853372965654504 0.299349060054895 0.450143880930327 0.300095920620218 0.450143880930327
Galnt2 ENSMUSG00000089704 0.781170242226513 0.781170242226513 0.514300775319626 0.781170242226513 0.575536202757516 0.781170242226513

Yersinia infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.710416009055326 0.710416009055326 0.180293335960318 0.270440003940477 0.177153312234059 0.270440003940477
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Map2k6 ENSMUSG00000020623 1 1 0.712057867818062 1 1 1
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Arpc1b ENSMUSG00000029622 0.044926265292481 0.134778795877443 0.178901132102685 0.268351698154027 0.297848640636702 0.297848640636702
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Nfatc1 ENSMUSG00000033016 0.57113445032749 0.711034989117171 0.0325051220296005 0.0975153660888015 0.711034989117171 0.711034989117171
Rac2 ENSMUSG00000033220 0.058823267388015 0.176469802164045 0.711854160331342 0.711854160331342 0.642864324224729 0.711854160331342
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Elmo1 ENSMUSG00000041112 0.779888212132595 1 0.852065168704833 1 1 1
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Cd8a ENSMUSG00000053977 0.708111938090394 0.853157406788312 0.50716883916608 0.853157406788312 0.853157406788312 0.853157406788312
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833
Arhgef12 ENSMUSG00000059495 0.453225835454266 0.578113371816017 0.255901190956604 0.578113371816017 0.578113371816017 0.578113371816017
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Endometrial cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cdh1 ENSMUSG00000000303 0.7802108304765 0.7802108304765 0.710416009055326 0.7802108304765 0.255530331334266 0.766590994002797
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Elk1 ENSMUSG00000009406 0.454600801949285 0.681901202923927 0.300095920620218 0.681901202923927 0.711240436189781 0.711240436189781
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Cdkn1a ENSMUSG00000023067 0.254414773803597 0.576973746230334 0.400265374208515 0.576973746230334 0.576973746230334 0.576973746230334
Axin1 ENSMUSG00000024182 0.706616781330066 0.706616781330066 0.211477675547592 0.634433026642775 0.450094379653806 0.675141569480709
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Tcf7l1 ENSMUSG00000055799 0.776919261684345 0.853480389728993 0.0953125666339398 0.285937699901819 0.853480389728993 0.853480389728993
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595

Apoptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Bbc3 ENSMUSG00000002083 0.21549027811633 0.21549027811633 0.146141353215796 0.21549027811633 0.177153312234059 0.21549027811633
Daxx ENSMUSG00000002307 0.5155648232968 0.5155648232968 0.454600801949285 0.5155648232968 0.148115998140416 0.444347994421247
Ctsz ENSMUSG00000016256 0.329176790045262 0.493765185067894 0.774176834800231 0.774176834800231 0.288654423610209 0.493765185067894
Birc5 ENSMUSG00000017716 0.852504981253341 0.852504981253341 0.456305241393103 0.684457862089655 0.254414773803597 0.684457862089655
Lmnb1 ENSMUSG00000024590 0.780851835278817 0.780851835278817 0.11810342389482 0.354310271684459 0.398108175780842 0.597162263671263
Rela ENSMUSG00000024927 0.85117361048289 0.85117361048289 0.204424977646738 0.613274932940214 0.455625354715449 0.683438032073173
Casp7 ENSMUSG00000025076 0.395196379647461 0.395196379647461 0.213307944885796 0.395196379647461 0.395196379647461 0.395196379647461
Chuk ENSMUSG00000025199 0.708534948098331 0.708534948098331 0.399548817627028 0.663317120301243 0.442211413534162 0.663317120301243
Ddit3 ENSMUSG00000025408 0.179945789077372 0.269918683616058 0.395196379647461 0.395196379647461 0.0953125666339398 0.269918683616058
Capn2 ENSMUSG00000026509 0.85117361048289 0.85117361048289 0.0763619660358786 0.229085898107636 0.513665062682276 0.770497594023414
Nras ENSMUSG00000027852 0.453570536021945 0.863304304136274 1 1 0.575536202757516 0.863304304136274
Diablo ENSMUSG00000029433 0.642864324224729 0.926333123228344 0.926333123228344 0.926333123228344 0.92622377157404 0.926333123228344
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Itpr2 ENSMUSG00000030287 0.708534948098331 0.708534948098331 0.640861491578951 0.708534948098331 0.0566379395854604 0.169913818756381
Fadd ENSMUSG00000031077 0.710208797518812 0.926333123228344 0.0588232673880149 0.176469802164045 0.926333123228344 0.926333123228344
Eif2ak3 ENSMUSG00000031668 0.299349060054895 0.683438032073173 0.455625354715449 0.683438032073173 0.926550375688041 0.926550375688041
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Itpr3 ENSMUSG00000042644 0.338592117141989 0.507888175712984 0.180293335960318 0.507888175712984 0.710416009055326 0.710416009055326
Jun ENSMUSG00000052684 0.643853282854191 0.926658283600152 0.578113371816017 0.926658283600152 0.926658283600152 0.926658283600152
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Tuba1a ENSMUSG00000072235 0.255901190956604 0.514934023620345 0.514934023620345 0.514934023620345 0.513665062682276 0.514934023620345

Signaling by Receptor Tyrosine Kinases

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Lck ENSMUSG00000000409 0.710416009055326 0.710416009055326 0.180293335960318 0.270440003940477 0.177153312234059 0.270440003940477
Hpn ENSMUSG00000001249 0.851954599472143 0.851954599472143 0.711854160331342 0.851954599472143 0.091411676944639 0.274235030833917
Jup ENSMUSG00000001552 0.853372965654504 1 0.300095920620218 0.900287761860653 1 1
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Axl ENSMUSG00000002602 0.120850531362929 0.362551594088787 0.346527959006435 0.514934023620344 0.514934023620344 0.514934023620344
Ncstn ENSMUSG00000003458 0.213307944885796 0.639923834657388 0.642864324224729 0.642864324224729 0.514300775319626 0.642864324224729
Stat3 ENSMUSG00000004040 0.342026805366747 0.51304020805012 0.0953125666339397 0.285937699901819 0.853801250889739 0.853801250889739
Grap ENSMUSG00000004837 0.0334587898203823 0.100376369461147 0.346899083932133 0.346899083932133 0.346527959006435 0.346899083932133
Hspb1 ENSMUSG00000004951 0.853694531487825 0.853694531487825 0.782117202022501 0.853694531487825 0.514934023620345 0.853694531487825
Polr2a ENSMUSG00000005198 0.852504981253341 0.852504981253341 0.21549027811633 0.64647083434899 0.78148726569172 0.852504981253341
Kit ENSMUSG00000005672 0.78180291566155 0.926333123228344 0.711034989117171 0.926333123228344 0.926333123228344 0.926333123228344
Aamp ENSMUSG00000006299 0.393724994268831 0.590587491403246 0.779888212132595 0.779888212132595 0.178901132102685 0.536703396308054
Cyba ENSMUSG00000006519 0.853694531487825 0.853694531487825 0.455625354715449 0.853694531487825 0.712057867818062 0.853694531487825
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fgfrl1 ENSMUSG00000008090 0.578113371816017 0.867170057724026 0.455625354715449 0.867170057724026 0.926550375688041 0.926550375688041
Ubc ENSMUSG00000008348 0.297848640636702 0.446772960955053 0.624685493301961 0.624685493301961 0.254414773803597 0.446772960955053
Lama5 ENSMUSG00000015647 0.643853282854191 0.643853282854191 0.576973746230334 0.643853282854191 0.297095062262362 0.643853282854191
Rab4a ENSMUSG00000019478 0.637274134311157 0.637274134311157 0.505169133438821 0.637274134311157 0.450444934184774 0.637274134311157
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Lama2 ENSMUSG00000019899 0.297095062262362 0.297095062262362 0.170434860179341 0.255652290269012 0.0741204440774082 0.222361332232225
Psen1 ENSMUSG00000019969 0.50716883916608 0.707899741868332 0.707899741868332 0.707899741868332 0.453570536021945 0.707899741868332
Egfr ENSMUSG00000020122 0.853372965654504 0.853372965654504 0.146800541856249 0.377126938563765 0.25141795904251 0.377126938563765
Frs2 ENSMUSG00000020170 0.513026869856283 0.513026869856283 0.178901132102685 0.370292939183197 0.246861959455465 0.370292939183197
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Tns3 ENSMUSG00000020422 0.577829325134931 0.577829325134931 0.148772260628989 0.446316781886968 0.384672302267076 0.577008453400614
Dnal4 ENSMUSG00000022420 0.177153312234059 0.531459936702177 0.642366752097095 0.711854160331342 0.711854160331342 0.711854160331342
Ncbp2 ENSMUSG00000022774 0.456305241393103 0.684457862089654 0.926550375688041 0.926550375688041 0.45596561163947 0.684457862089654
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Mlst8 ENSMUSG00000024142 0.148115998140415 0.444347994421246 0.642864324224729 0.642864324224729 0.399548817627028 0.599323226440542
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Hgs ENSMUSG00000025793 0.399548817627028 0.514934023620344 0.514934023620344 0.514934023620344 0.346899083932133 0.514934023620344
Fn1 ENSMUSG00000026193 0.925444427431699 0.925444427431699 0.0930846407079409 0.279253922123823 0.443669460449296 0.665504190673944
Ralgds ENSMUSG00000026821 0.342405296020881 0.513607944031322 0.775217051297351 0.775217051297351 0.024062085667391 0.0721862570021729
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Pcsk6 ENSMUSG00000030513 0.205174703261494 0.252920381501206 0.252920381501206 0.252920381501206 0.177853449259986 0.252920381501206
Dusp4 ENSMUSG00000031530 0.148772260628989 0.446316781886968 0.343537039781257 0.515305559671886 0.578113371816017 0.578113371816017
Plat ENSMUSG00000031538 0.400265374208515 0.454600801949285 0.454600801949285 0.454600801949285 0.297095062262362 0.454600801949285
Cdh5 ENSMUSG00000031871 0.643359829732651 0.643359829732651 0.454600801949285 0.643359829732651 0.338592117141989 0.643359829732651
Chek1 ENSMUSG00000032113 0.514934023620345 0.578113371816017 0.578113371816017 0.578113371816017 0.5155648232968 0.578113371816017
Csk ENSMUSG00000032312 0.639337105615664 0.780851835278818 0.573791743469336 0.780851835278818 0.780851835278818 0.780851835278818
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Pik3r4 ENSMUSG00000032571 0.578113371816017 0.78180291566155 0.78180291566155 0.78180291566155 0.5155648232968 0.78180291566155
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Cbl ENSMUSG00000034342 0.0763619660358786 0.229085898107636 0.577829325134931 0.642366752097095 0.642366752097095 0.642366752097095
Fgf1 ENSMUSG00000036585 0.926550375688041 0.926550375688041 0.853801250889739 0.926550375688041 0.452880492349546 0.926550375688041
Spry1 ENSMUSG00000037211 0.254787123615605 0.764361370846815 0.576973746230334 0.782117202022501 0.782117202022501 0.782117202022501
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Atp6v0a2 ENSMUSG00000038023 0.926550375688041 0.926550375688041 0.853694531487825 0.926550375688041 0.78180291566155 0.926550375688041
Atp6v0a4 ENSMUSG00000038600 0.45596561163947 0.683948417459205 0.710001140920767 0.710001140920767 0.252920381501207 0.683948417459205
Esrp1 ENSMUSG00000040728 0.49372294985924 1 1 1 0.850265736951714 1
Elmo1 ENSMUSG00000041112 0.779888212132595 1 0.852065168704833 1 1 1
Hnrnpf ENSMUSG00000042079 0.180293335960318 0.270440003940477 0.0116356061791785 0.0349068185375355 0.342405296020881 0.342405296020881
Ptpn11 ENSMUSG00000043733 0.710208797518812 0.711650020253571 0.711650020253571 0.711650020253571 0.252920381501207 0.711650020253571
Arf6 ENSMUSG00000044147 0.454600801949285 0.514934023620345 0.299349060054895 0.514934023620345 0.514934023620345 0.514934023620345
Tlr9 ENSMUSG00000045322 0.511742979522635 0.767614469283952 0.853801250889739 0.853801250889739 0.11810342389482 0.354310271684459
Lamb2 ENSMUSG00000052911 0.399548817627028 0.599323226440542 1 1 0.180293335960318 0.540880007880955
Ntrk2 ENSMUSG00000055254 0.576112968612194 0.643853282854191 0.643853282854191 0.643853282854191 0.252920381501207 0.643853282854191
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833
Ppp2r5d ENSMUSG00000059409 0.300095920620218 0.849890346946107 0.566593564630738 0.849890346946107 0.851732715229127 0.851732715229127
Grb2 ENSMUSG00000059923 0.509798138101151 0.764697207151727 0.0325051220296005 0.0975153660888015 1 1
Mapk3 ENSMUSG00000063065 0.455625354715449 0.779888212132595 0.779888212132595 0.779888212132595 0.577259514257969 0.779888212132595
Col4a4 ENSMUSG00000067158 0.453225835454266 0.453225835454266 0.180293335960318 0.270440003940477 0.00463747559282087 0.0139124267784626

Signaling by VEGF

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Jup ENSMUSG00000001552 0.853372965654504 1 0.300095920620218 0.900287761860653 1 1
Akt1 ENSMUSG00000001729 0.781170242226513 0.781170242226513 0.711240436189781 0.781170242226513 0.255530331334266 0.766590994002798
Rac1 ENSMUSG00000001847 0.851732715229127 0.851732715229127 0.779238691542963 0.851732715229127 0.455625354715449 0.851732715229127
Axl ENSMUSG00000002602 0.120850531362929 0.362551594088787 0.346527959006435 0.514934023620344 0.514934023620344 0.514934023620344
Hspb1 ENSMUSG00000004951 0.853694531487825 0.853694531487825 0.782117202022501 0.853694531487825 0.514934023620345 0.853694531487825
Cyba ENSMUSG00000006519 0.853694531487825 0.853694531487825 0.455625354715449 0.853694531487825 0.712057867818062 0.853694531487825
Rhoa ENSMUSG00000007815 0.345037391052887 0.578113371816017 0.578113371816017 0.578113371816017 0.393724994268831 0.578113371816017
Fyn ENSMUSG00000019843 0.641867098978197 0.782117202022501 0.0432318933800775 0.129695680140232 0.782117202022501 0.782117202022501
Flt4 ENSMUSG00000020357 0.450444934184773 0.67566740127716 0.852832278580641 0.852832278580641 0.297848640636702 0.67566740127716
Pak2 ENSMUSG00000022781 0.643853282854191 0.853801250889739 0.853801250889739 0.853801250889739 0.255530331334266 0.766590994002797
Mlst8 ENSMUSG00000024142 0.148115998140415 0.444347994421246 0.642864324224729 0.642864324224729 0.399548817627028 0.599323226440542
Vegfb ENSMUSG00000024962 0.926658283600152 0.926658283600152 0.514934023620345 0.926658283600152 0.853694531487825 0.926658283600152
Wasf2 ENSMUSG00000028868 0.852940894477647 0.852940894477647 0.148772260628989 0.446316781886967 0.640861491578951 0.852940894477647
Nos3 ENSMUSG00000028978 0.300095920620218 0.853480389728993 0.853480389728993 0.853480389728993 0.577259514257969 0.853480389728993
Mtor ENSMUSG00000028991 0.290210015182478 0.870630045547434 0.851061028660105 1 1 1
Actb ENSMUSG00000029580 0.347639524025037 0.521459286037555 0.7802108304765 0.7802108304765 0.299349060054895 0.521459286037555
Wasf3 ENSMUSG00000029636 0.513665062682276 0.711034989117171 0.711034989117171 0.711034989117171 0.454942951775342 0.711034989117171
Cdh5 ENSMUSG00000031871 0.643359829732651 0.643359829732651 0.454600801949285 0.643359829732651 0.338592117141989 0.643359829732651
Pik3cb ENSMUSG00000032462 1 1 0.78180291566155 1 0.711854160331342 1
Vav1 ENSMUSG00000034116 0.392243127063687 0.683438032073173 0.926441990075769 0.926441990075769 0.455625354715449 0.683438032073173
Ctnna1 ENSMUSG00000037815 0.347639524025037 0.521459286037555 0.710208797518812 0.710208797518812 0.250285839267991 0.521459286037555
Elmo1 ENSMUSG00000041112 0.779888212132595 1 0.852065168704833 1 1 1
Dock1 ENSMUSG00000058325 0.852065168704833 0.852065168704833 0.179945789077371 0.539837367232114 0.578113371816017 0.852065168704833

lightpink1

Hepatocellular carcinoma

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Txnrd3 ENSMUSG00000000811 0.452880492349546 0.452880492349546 0.000807274199958701 0.0024218225998761 0.028315485753685 0.0424732286305275
Dvl3 ENSMUSG00000003233 0.146800541856249 0.270440003940478 0.180293335960318 0.270440003940478 0.782117202022501 0.782117202022501
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Fzd3 ENSMUSG00000007989 0.0761127945805735 0.114542949053818 0.0763619660358786 0.114542949053818 0.514934023620345 0.514934023620345
Gadd45b ENSMUSG00000015312 0.177153312234059 0.449023590082343 0.299349060054895 0.449023590082343 0.513665062682276 0.513665062682276
Tgfb3 ENSMUSG00000021253 0.299349060054895 0.449023590082343 0.027258620557079 0.0817758616712369 0.513665062682276 0.513665062682276
Csnk1a1 ENSMUSG00000024576 0.00481536616919078 0.0144460985075723 0.216214347033995 0.324321520550992 0.926658283600152 0.926658283600152
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Dpf1 ENSMUSG00000030584 0.343537039781257 0.456305241393103 0.456305241393103 0.456305241393103 0.454600801949285 0.456305241393103
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993

Colorectal cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Gadd45b ENSMUSG00000015312 0.177153312234059 0.449023590082343 0.299349060054895 0.449023590082343 0.513665062682276 0.513665062682276
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Tgfb3 ENSMUSG00000021253 0.299349060054895 0.449023590082343 0.027258620557079 0.0817758616712369 0.513665062682276 0.513665062682276
Bcl2l11 ENSMUSG00000027381 0.0944774830993426 0.141716224649014 0.00878055595853348 0.0263416678756005 0.397021051130447 0.397021051130447
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Bcl2 ENSMUSG00000057329 0.148772260628989 0.223158390943484 0.146800541856249 0.223158390943484 0.346527959006435 0.346527959006435

Wnt signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dvl3 ENSMUSG00000003233 0.146800541856249 0.270440003940478 0.180293335960318 0.270440003940478 0.782117202022501 0.782117202022501
Wisp1 ENSMUSG00000005124 0.347639524025037 0.521459286037555 0.0391520668616184 0.117456200584855 1 1
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Fzd3 ENSMUSG00000007989 0.0761127945805735 0.114542949053818 0.0763619660358786 0.114542949053818 0.514934023620345 0.514934023620345
Ppp3cc ENSMUSG00000022092 0.214037080764326 0.321055621146488 5.17062302895137e-05 0.000155118690868541 0.851954599472143 0.851954599472143
Csnk1a1 ENSMUSG00000024576 0.00481536616919078 0.0144460985075723 0.216214347033995 0.324321520550992 0.926658283600152 0.926658283600152
Tle3 ENSMUSG00000032280 0.0947558980989551 0.142133847148433 0.0328221470541517 0.0984664411624552 0.853801250889739 0.853801250889739
Tle2 ENSMUSG00000034771 1 1 0.0231500557096833 0.0694501671290499 0.711854160331342 1
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993

MicroRNAs in cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Fzd3 ENSMUSG00000007989 0.0761127945805735 0.114542949053818 0.0763619660358786 0.114542949053818 0.514934023620345 0.514934023620345
Hdac4 ENSMUSG00000026313 0.576973746230334 0.578396848531894 0.346527959006435 0.578396848531894 0.578396848531894 0.578396848531894
Zeb2 ENSMUSG00000026872 0.119631084167592 0.179446626251387 0.0726276229843141 0.179446626251387 0.711854160331342 0.711854160331342
Bcl2l11 ENSMUSG00000027381 0.0944774830993426 0.141716224649014 0.00878055595853348 0.0263416678756005 0.397021051130447 0.397021051130447
Tnc ENSMUSG00000028364 0.926441990075769 0.926441990075769 0.177153312234059 0.531459936702178 0.514934023620345 0.772401035430517
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Mcl1 ENSMUSG00000038612 0.0763619660358786 0.229085898107636 0.253294730253594 0.379942095380391 0.853694531487825 0.853694531487825
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993
Irs1 ENSMUSG00000055980 0.096425230538547 0.144637845807821 0.0166824765447319 0.0500474296341957 0.774871910813158 0.774871910813158
Bcl2 ENSMUSG00000057329 0.148772260628989 0.223158390943484 0.146800541856249 0.223158390943484 0.346527959006435 0.346527959006435
Bmpr2 ENSMUSG00000067336 0.024062085667391 0.0721862570021729 0.119631084167592 0.179446626251387 0.45596561163947 0.45596561163947

Growth hormone synthesis, secretion and action

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Igfbp3 ENSMUSG00000020427 0.454942951775341 0.682414427663012 0.395928178642446 0.682414427663012 0.782117202022501 0.782117202022501
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993
Junb ENSMUSG00000052837 0.0449262652924809 0.134778795877443 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Socs3 ENSMUSG00000053113 0.45596561163947 0.683948417459205 0.120850531362929 0.362551594088788 0.926658283600152 0.926658283600152
Irs1 ENSMUSG00000055980 0.096425230538547 0.144637845807821 0.0166824765447319 0.0500474296341957 0.774871910813158 0.774871910813158

Gastric cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dvl3 ENSMUSG00000003233 0.146800541856249 0.270440003940478 0.180293335960318 0.270440003940478 0.782117202022501 0.782117202022501
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Fzd3 ENSMUSG00000007989 0.0761127945805735 0.114542949053818 0.0763619660358786 0.114542949053818 0.514934023620345 0.514934023620345
Gadd45b ENSMUSG00000015312 0.177153312234059 0.449023590082343 0.299349060054895 0.449023590082343 0.513665062682276 0.513665062682276
Tgfb3 ENSMUSG00000021253 0.299349060054895 0.449023590082343 0.027258620557079 0.0817758616712369 0.513665062682276 0.513665062682276
Csnk1a1 ENSMUSG00000024576 0.00481536616919078 0.0144460985075723 0.216214347033995 0.324321520550992 0.926658283600152 0.926658283600152
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Bcl2 ENSMUSG00000057329 0.148772260628989 0.223158390943484 0.146800541856249 0.223158390943484 0.346527959006435 0.346527959006435

Osteoclast differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fosb ENSMUSG00000003545 0.0449262652924809 0.134778795877443 0.454942951775341 0.682414427663012 0.853801250889739 0.853801250889739
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Ppp3cc ENSMUSG00000022092 0.214037080764326 0.321055621146488 5.17062302895137e-05 0.000155118690868541 0.851954599472143 0.851954599472143
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Fosl2 ENSMUSG00000029135 0.0222505050945549 0.0667515152836646 0.0743693776059062 0.111554066408859 1 1
Junb ENSMUSG00000052837 0.0449262652924809 0.134778795877443 0.711854160331342 0.853801250889739 0.853801250889739 0.853801250889739
Socs3 ENSMUSG00000053113 0.45596561163947 0.683948417459205 0.120850531362929 0.362551594088788 0.926658283600152 0.926658283600152

Amphetamine addiction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fosb ENSMUSG00000003545 0.0449262652924809 0.134778795877443 0.454942951775341 0.682414427663012 0.853801250889739 0.853801250889739
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Ppp3cc ENSMUSG00000022092 0.214037080764326 0.321055621146488 5.17062302895137e-05 0.000155118690868541 0.851954599472143 0.851954599472143
Arc ENSMUSG00000022602 0.214764523938594 0.644293571815781 0.782117202022501 1 1 1
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993

Breast cancer

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dvl3 ENSMUSG00000003233 0.146800541856249 0.270440003940478 0.180293335960318 0.270440003940478 0.782117202022501 0.782117202022501
Apc ENSMUSG00000005871 0.513026869856283 0.769540304784424 0.0230207752632623 0.0690623257897869 1 1
Fzd3 ENSMUSG00000007989 0.0761127945805735 0.114542949053818 0.0763619660358786 0.114542949053818 0.514934023620345 0.514934023620345
Gadd45b ENSMUSG00000015312 0.177153312234059 0.449023590082343 0.299349060054895 0.449023590082343 0.513665062682276 0.513665062682276
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Csnk1a1 ENSMUSG00000024576 0.00481536616919078 0.0144460985075723 0.216214347033995 0.324321520550992 0.926658283600152 0.926658283600152
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133

MAPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1e ENSMUSG00000004110 0.0936419271039908 0.280925781311972 0.252545530864481 0.378818296296721 0.711854160331342 0.711854160331342
Gadd45b ENSMUSG00000015312 0.177153312234059 0.449023590082343 0.299349060054895 0.449023590082343 0.513665062682276 0.513665062682276
Kitl ENSMUSG00000019966 0.148115998140416 0.222173997210623 0.0575107614292586 0.172532284287776 0.57466664340579 0.57466664340579
Fos ENSMUSG00000021250 0.0113089139751576 0.0339267419254727 0.287873078401389 0.431809617602084 0.642366752097095 0.642366752097095
Tgfb3 ENSMUSG00000021253 0.299349060054895 0.449023590082343 0.027258620557079 0.0817758616712369 0.513665062682276 0.513665062682276
Ppp3cc ENSMUSG00000022092 0.214037080764326 0.321055621146488 5.17062302895137e-05 0.000155118690868541 0.851954599472143 0.851954599472143
Nr4a1 ENSMUSG00000023034 0.180293335960318 0.270440003940477 0.175044824745981 0.270440003940477 0.711034989117171 0.711034989117171
Dusp1 ENSMUSG00000024190 0.146141353215796 0.399548817627028 0.399548817627028 0.399548817627028 0.398108175780842 0.399548817627028
Dusp5 ENSMUSG00000034765 0.0447373296833729 0.0671059945250594 0.0129100470219436 0.0387301410658307 0.846584006881321 0.846584006881321
Prkca ENSMUSG00000050965 0.348008842235184 0.522013263352776 0.00236268169165983 0.00708804507497948 0.853480389728993 0.853480389728993

Type II diabetes mellitus

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cacna1e ENSMUSG00000004110 0.0936419271039908 0.280925781311972 0.252545530864481 0.378818296296721 0.711854160331342 0.711854160331342
Pik3r3 ENSMUSG00000028698 0.0243249029874197 0.0729747089622591 0.120850531362929 0.181275797044394 0.346899083932133 0.346899083932133
Socs3 ENSMUSG00000053113 0.45596561163947 0.683948417459205 0.120850531362929 0.362551594088788 0.926658283600152 0.926658283600152
Irs1 ENSMUSG00000055980 0.096425230538547 0.144637845807821 0.0166824765447319 0.0500474296341957 0.774871910813158 0.774871910813158

lightskyblue

Estrogen biosynthesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr1b7 ENSMUSG00000052131 0.650262661949838 0.650262661949838 0.280002632651122 0.650262661949838 0.650262661949838 0.650262661949838

Extrinsic Pathway of Fibrin Clot Formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tfpi ENSMUSG00000027082 0.511742979522636 0.767614469283954 0.782117202022501 0.782117202022501 0.50716883916608 0.767614469283954

Metabolism of steroids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp27b1 ENSMUSG00000006724 0.438889219142351 0.658333828713526 0.704220158648919 0.704220158648919 0.295581119060361 0.658333828713526
Akr1b7 ENSMUSG00000052131 0.650262661949838 0.650262661949838 0.280002632651122 0.650262661949838 0.650262661949838 0.650262661949838

Mitotic Metaphase/Anaphase Transition

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo5 ENSMUSG00000019773 1 1 0.171859370212435 0.515578110637305 0.775217051297351 1

Phosphorylation of Emi1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fbxo5 ENSMUSG00000019773 1 1 0.171859370212435 0.515578110637305 0.775217051297351 1

Vitamin D (calciferol) metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp27b1 ENSMUSG00000006724 0.438889219142351 0.658333828713526 0.704220158648919 0.704220158648919 0.295581119060361 0.658333828713526

Vitamins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp27b1 ENSMUSG00000006724 0.438889219142351 0.658333828713526 0.704220158648919 0.704220158648919 0.295581119060361 0.658333828713526

lightskyblue2

[1] “No significantly overrepresented pathways reported”

limegreen

[1] “No significantly overrepresented pathways reported”

mediumorchid1

Starch and sucrose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Carbohydrate digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Salivary secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Pancreatic secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Bcmo1 ENSMUSG00000031845 0.236337185850513 0.35450577877577 0.0277488516119482 0.0832465548358446 0.567207316884046 0.567207316884046
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Digestion of dietary carbohydrate

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Digestion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

Digestion and absorption

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Amy2a5 ENSMUSG00000074268 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a3 ENSMUSG00000093931 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a2 ENSMUSG00000096569 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278
Amy2a4 ENSMUSG00000096770 0.275861418394615 0.413792127591923 0.178901132102685 0.413792127591923 0.558695769640278 0.558695769640278

betaKlotho-mediated ligand binding

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Klb ENSMUSG00000029195 0.0163700297194363 0.0245550445791544 0.0155487269883892 0.0245550445791544 0.0961471511181031 0.0961471511181031

mistyrose

[1] “No significantly overrepresented pathways reported”

oldlace

[1] “No significantly overrepresented pathways reported”

pink

Cytokine-cytokine receptor interaction

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il7r ENSMUSG00000003882 5.46967066778587e-05 0.000164090120033576 0.852614322863384 0.852614322863384 0.448685536739372 0.673028305109058
Il27ra ENSMUSG00000005465 0.255530331334266 0.450143880930327 0.710001140920767 0.710001140920767 0.300095920620218 0.450143880930327
Tgfbr1 ENSMUSG00000007613 5.46967066778586e-05 0.000164090120033576 0.146471068967595 0.219706603451393 0.85326530496423 0.85326530496423
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Il15ra ENSMUSG00000023206 0.120850531362929 0.181275797044394 0.298599969973533 0.298599969973533 0.0753654386865988 0.181275797044394
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Il1rl1 ENSMUSG00000026069 0.00477055016690543 0.0143116505007163 0.926604389137101 0.926604389137101 0.044737329683373 0.0671059945250595
Csf3r ENSMUSG00000028859 0.174692232033629 0.17610058307789 0.17610058307789 0.17610058307789 0.144820068500793 0.17610058307789
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Lifr ENSMUSG00000054263 5.17062302895139e-05 0.000155118690868542 0.0566379395854604 0.0849569093781906 0.709375484777034 0.709375484777034
Ccr5 ENSMUSG00000079227 0.00264953297731415 0.00424655905783326 0.00283103937188884 0.00424655905783326 0.00481536616919077 0.00481536616919077

Toll-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Tuberculosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Mrc1 ENSMUSG00000026712 5.62387620362728e-05 0.000168716286108818 0.342026805366747 0.342405296020882 0.342405296020882 0.342405296020882
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Cebpg ENSMUSG00000056216 0.0015541259555958 0.00466237786678739 0.643359829732651 0.643359829732651 0.0566379395854603 0.0849569093781905
Fcer1g ENSMUSG00000058715 5.78125466309114e-05 0.000173437639892734 0.0766111619812296 0.0766111619812296 0.058823267388015 0.0766111619812296
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641

Staphylococcus aureus infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Krt19 ENSMUSG00000020911 0.0756145297453646 0.226843589236094 0.853372965654504 0.853372965654504 0.853372965654504 0.853372965654504
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
C3ar1 ENSMUSG00000040552 5.46967066778586e-05 5.62387620362729e-05 5.46967066778587e-05 5.62387620362729e-05 5.62387620362729e-05 5.62387620362729e-05
Selplg ENSMUSG00000048163 5.17062302895137e-05 0.000155118690868541 0.249528554620971 0.249528554620971 0.01710279005982 0.0256541850897299
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554
Ptafr ENSMUSG00000056529 5.31859920215278e-05 0.000159557976064583 0.78132892626786 0.78132892626786 0.178901132102685 0.268351698154027
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641
Gm14851 ENSMUSG00000061958 0.113190884633071 0.339572653899212 0.926333123228344 0.926333123228344 0.450794830295119 0.676192245442679

Chagas disease

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfbr1 ENSMUSG00000007613 5.46967066778586e-05 0.000164090120033576 0.146471068967595 0.219706603451393 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Gna15 ENSMUSG00000034792 0.000819575681707138 0.00245872704512142 0.397384062266614 0.397384062266614 0.00743512899358789 0.0111526934903818
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074

NOD-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Nlrx1 ENSMUSG00000032109 0.0449262652924809 0.134778795877443 0.643606811957488 0.643606811957488 0.096147151118103 0.144220726677154
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Txnip ENSMUSG00000038393 5.02570344982353e-05 0.000150771103494706 0.637793186752488 0.637793186752488 0.0969812105731563 0.145471815859735
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Gm14851 ENSMUSG00000061958 0.113190884633071 0.339572653899212 0.926333123228344 0.926333123228344 0.450794830295119 0.676192245442679
Ifi204 ENSMUSG00000073489 2.05510033519727e-05 6.1653010055918e-05 0.00113663395596434 0.0017049509339465 0.120545895661627 0.120545895661627
AI607873 ENSMUSG00000073490 5.02570344982356e-05 0.000150771103494707 0.00161470887631957 0.00161470887631957 0.000771096743445033 0.00115664511516755
Nlrp12 ENSMUSG00000078817 0.00392242458502081 0.0117672737550624 0.637274134311157 0.637274134311157 0.163231646296655 0.244847469444983

Viral protein interaction with cytokine and cytokine receptor

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Ccr5 ENSMUSG00000079227 0.00264953297731415 0.00424655905783326 0.00283103937188884 0.00424655905783326 0.00481536616919077 0.00481536616919077

Coronavirus disease - COVID-19

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Mb21d1 ENSMUSG00000032344 0.17750354896016 0.26625532344024 0.853372965654504 0.853372965654504 0.0426702157436794 0.128010647231038
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
C3ar1 ENSMUSG00000040552 5.46967066778586e-05 5.62387620362729e-05 5.46967066778587e-05 5.62387620362729e-05 5.62387620362729e-05 5.62387620362729e-05
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554

Natural killer cell mediated cytotoxicity

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd48 ENSMUSG00000015355 0.000387171985540247 0.00116151595662074 0.345037391052887 0.345037391052887 0.0436072256433733 0.0654108384650599
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Sh3bp2 ENSMUSG00000054520 0.00481536616919077 0.0144460985075723 0.926658283600152 0.926658283600152 0.926550375688041 0.926658283600152
Fcer1g ENSMUSG00000058715 5.78125466309114e-05 0.000173437639892734 0.0766111619812296 0.0766111619812296 0.058823267388015 0.0766111619812296
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641

Phagosome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Msr1 ENSMUSG00000025044 5.62387620362728e-05 5.78125466309116e-05 5.62387620362728e-05 5.78125466309116e-05 5.78125466309116e-05 5.78125466309116e-05
Mrc1 ENSMUSG00000026712 5.62387620362728e-05 0.000168716286108818 0.342026805366747 0.342405296020882 0.342405296020882 0.342405296020882
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641

Influenza A

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Nlrx1 ENSMUSG00000032109 0.0449262652924809 0.134778795877443 0.643606811957488 0.643606811957488 0.096147151118103 0.144220726677154
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263

Leishmaniasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641

Pertussis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Lipid and atherosclerosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Malaria

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566

Hematopoietic cell lineage

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il7r ENSMUSG00000003882 5.46967066778587e-05 0.000164090120033576 0.852614322863384 0.852614322863384 0.448685536739372 0.673028305109058
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Csf3r ENSMUSG00000028859 0.174692232033629 0.17610058307789 0.17610058307789 0.17610058307789 0.144820068500793 0.17610058307789
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Siglech ENSMUSG00000051504 5.46967066778586e-05 8.20450600167879e-05 5.02570344982356e-05 8.20450600167879e-05 0.000157492167861666 0.000157492167861666

Legionellosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566

Salmonella infection

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Ptprc ENSMUSG00000026395 0.00289311433957183 0.00867934301871548 0.18064054691103 0.270960820366546 0.299349060054895 0.299349060054895
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074

Cytosolic DNA-sensing pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Mb21d1 ENSMUSG00000032344 0.17750354896016 0.26625532344024 0.853372965654504 0.853372965654504 0.0426702157436794 0.128010647231038
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983

Neutrophil extracellular trap formation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
Selplg ENSMUSG00000048163 5.17062302895137e-05 0.000155118690868541 0.249528554620971 0.249528554620971 0.01710279005982 0.0256541850897299
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641

NF-kappa B signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935
Bcl2a1b ENSMUSG00000089929 5.78125466309114e-05 0.000173437639892734 0.0164739112492867 0.023800255149993 0.023800255149993 0.023800255149993

Amoebiasis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr2 ENSMUSG00000027995 5.46967066778586e-05 0.000164090120033576 0.00481536616919077 0.00481536616919077 0.00157416039719768 0.00236124059579652
Itgam ENSMUSG00000030786 0.000394209637342663 0.000591314456013994 0.0197526720827851 0.0197526720827851 3.62234658965409e-05 0.000108670397689623
Gna15 ENSMUSG00000034792 0.000819575681707138 0.00245872704512142 0.397384062266614 0.397384062266614 0.00743512899358789 0.0111526934903818
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566

RIG-I-like receptor signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Dhx58 ENSMUSG00000017830 0.0964252305385472 0.171859370212435 0.140833168780851 0.171859370212435 0.171859370212435 0.171859370212435
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Nlrx1 ENSMUSG00000032109 0.0449262652924809 0.134778795877443 0.643606811957488 0.643606811957488 0.096147151118103 0.144220726677154
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983

Osteoclast differentiation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tgfbr1 ENSMUSG00000007613 5.46967066778586e-05 0.000164090120033576 0.146471068967595 0.219706603451393 0.85326530496423 0.85326530496423
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Pirb ENSMUSG00000058818 0.00477055016690543 0.0143116505007163 0.119631084167592 0.179446626251387 0.295581119060361 0.295581119060361
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641
Gm14548 ENSMUSG00000074417 0.00437574110570137 0.00437574110570139 0.00437574110570136 0.00437574110570139 0.00437574110570139 0.00437574110570139

Necroptosis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Il7r ENSMUSG00000003882 5.46967066778587e-05 0.000164090120033576 0.852614322863384 0.852614322863384 0.448685536739372 0.673028305109058
Il27ra ENSMUSG00000005465 0.255530331334266 0.450143880930327 0.710001140920767 0.710001140920767 0.300095920620218 0.450143880930327
Slamf6 ENSMUSG00000015314 0.000164597779190222 0.000493793337570665 0.024062085667391 0.0360931285010865 0.0766111619812295 0.0766111619812295
Cd68 ENSMUSG00000018774 0.000844544805216501 0.0025336344156495 0.0331400397096515 0.0497100595644772 0.0566379395854602 0.0566379395854602
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Rnf19a ENSMUSG00000022280 0.00477055016690543 0.0143116505007163 0.711034989117171 0.711034989117171 0.395928178642446 0.593892267963669
Il15ra ENSMUSG00000023206 0.120850531362929 0.181275797044394 0.298599969973533 0.298599969973533 0.0753654386865988 0.181275797044394
Tnf ENSMUSG00000024401 0.0040437778332623 0.0065662762036561 0.00437751746910406 0.0065662762036561 0.0110666956860337 0.0110666956860337
Hk3 ENSMUSG00000025877 4.34560606330504e-05 0.000130368181899151 0.852940894477647 0.852940894477647 0.00446325197783099 0.00669487796674649
Il1rl1 ENSMUSG00000026069 0.00477055016690543 0.0143116505007163 0.926604389137101 0.926604389137101 0.044737329683373 0.0671059945250595
Ptprc ENSMUSG00000026395 0.00289311433957183 0.00867934301871548 0.18064054691103 0.270960820366546 0.299349060054895 0.299349060054895
Mrc1 ENSMUSG00000026712 5.62387620362728e-05 0.000168716286108818 0.342026805366747 0.342405296020882 0.342405296020882 0.342405296020882
Csf3r ENSMUSG00000028859 0.174692232033629 0.17610058307789 0.17610058307789 0.17610058307789 0.144820068500793 0.17610058307789
Ifi30 ENSMUSG00000031838 0.00283103937188883 0.0084931181156665 0.346899083932133 0.520348625898199 0.853694531487825 0.853694531487825
Nlrx1 ENSMUSG00000032109 0.0449262652924809 0.134778795877443 0.643606811957488 0.643606811957488 0.096147151118103 0.144220726677154
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
Asb10 ENSMUSG00000038204 0.00768144932639892 0.0230443479791968 0.455625354715449 0.578113371816017 0.578113371816017 0.578113371816017
Txnip ENSMUSG00000038393 5.02570344982353e-05 0.000150771103494706 0.637793186752488 0.637793186752488 0.0969812105731563 0.145471815859735
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Siglec5 ENSMUSG00000039013 0.094755898098955 0.0964252305385472 0.0964252305385472 0.0964252305385472 0.0241933715424143 0.0725801146272428
C3ar1 ENSMUSG00000040552 5.46967066778586e-05 5.62387620362729e-05 5.46967066778587e-05 5.62387620362729e-05 5.62387620362729e-05 5.62387620362729e-05
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Siglech ENSMUSG00000051504 5.46967066778586e-05 8.20450600167879e-05 5.02570344982356e-05 8.20450600167879e-05 0.000157492167861666 0.000157492167861666
Lifr ENSMUSG00000054263 5.17062302895139e-05 0.000155118690868542 0.0566379395854604 0.0849569093781906 0.709375484777034 0.709375484777034
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935
Ptafr ENSMUSG00000056529 5.31859920215278e-05 0.000159557976064583 0.78132892626786 0.78132892626786 0.178901132102685 0.268351698154027
Fcer1g ENSMUSG00000058715 5.78125466309114e-05 0.000173437639892734 0.0766111619812296 0.0766111619812296 0.058823267388015 0.0766111619812296
Pirb ENSMUSG00000058818 0.00477055016690543 0.0143116505007163 0.119631084167592 0.179446626251387 0.295581119060361 0.295581119060361
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641
Gm14851 ENSMUSG00000061958 0.113190884633071 0.339572653899212 0.926333123228344 0.926333123228344 0.450794830295119 0.676192245442679
Cd300lb ENSMUSG00000063193 0.000131240359395912 0.000393721078187735 0.0445485589872462 0.0445485589872462 0.0445485589872461 0.0445485589872462
Ear2 ENSMUSG00000072596 0.290984282074805 0.340887582990546 0.0129100470219435 0.0387301410658306 0.340887582990546 0.340887582990546
Ifi204 ENSMUSG00000073489 2.05510033519727e-05 6.1653010055918e-05 0.00113663395596434 0.0017049509339465 0.120545895661627 0.120545895661627
Gm14548 ENSMUSG00000074417 0.00437574110570137 0.00437574110570139 0.00437574110570136 0.00437574110570139 0.00437574110570139 0.00437574110570139
Clec4g ENSMUSG00000074491 0.00230764810793429 0.00692294432380285 0.111339700035808 0.111339700035808 0.0421101560083838 0.0631652340125757

Innate Immune System

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd68 ENSMUSG00000018774 0.000844544805216501 0.0025336344156495 0.0331400397096515 0.0497100595644772 0.0566379395854602 0.0566379395854602
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Hk3 ENSMUSG00000025877 4.34560606330504e-05 0.000130368181899151 0.852940894477647 0.852940894477647 0.00446325197783099 0.00669487796674649
Ptprc ENSMUSG00000026395 0.00289311433957183 0.00867934301871548 0.18064054691103 0.270960820366546 0.299349060054895 0.299349060054895
Nlrx1 ENSMUSG00000032109 0.0449262652924809 0.134778795877443 0.643606811957488 0.643606811957488 0.096147151118103 0.144220726677154
C1qa ENSMUSG00000036887 0.0231500557096833 0.0694501671290499 0.578113371816017 0.578113371816017 0.511742979522636 0.578113371816017
Txnip ENSMUSG00000038393 5.02570344982353e-05 0.000150771103494706 0.637793186752488 0.637793186752488 0.0969812105731563 0.145471815859735
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Siglec5 ENSMUSG00000039013 0.094755898098955 0.0964252305385472 0.0964252305385472 0.0964252305385472 0.0241933715424143 0.0725801146272428
C3ar1 ENSMUSG00000040552 5.46967066778586e-05 5.62387620362729e-05 5.46967066778587e-05 5.62387620362729e-05 5.62387620362729e-05 5.62387620362729e-05
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935
Ptafr ENSMUSG00000056529 5.31859920215278e-05 0.000159557976064583 0.78132892626786 0.78132892626786 0.178901132102685 0.268351698154027
Fcer1g ENSMUSG00000058715 5.78125466309114e-05 0.000173437639892734 0.0766111619812296 0.0766111619812296 0.058823267388015 0.0766111619812296
Pirb ENSMUSG00000058818 0.00477055016690543 0.0143116505007163 0.119631084167592 0.179446626251387 0.295581119060361 0.295581119060361
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641
Gm14851 ENSMUSG00000061958 0.113190884633071 0.339572653899212 0.926333123228344 0.926333123228344 0.450794830295119 0.676192245442679
Cd300lb ENSMUSG00000063193 0.000131240359395912 0.000393721078187735 0.0445485589872462 0.0445485589872462 0.0445485589872461 0.0445485589872462
Ear2 ENSMUSG00000072596 0.290984282074805 0.340887582990546 0.0129100470219435 0.0387301410658306 0.340887582990546 0.340887582990546
Ifi204 ENSMUSG00000073489 2.05510033519727e-05 6.1653010055918e-05 0.00113663395596434 0.0017049509339465 0.120545895661627 0.120545895661627
Gm14548 ENSMUSG00000074417 0.00437574110570137 0.00437574110570139 0.00437574110570136 0.00437574110570139 0.00437574110570139 0.00437574110570139

Caspase activation via Death Receptors in the presence of ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Caspase activation via extrinsic apoptotic signalling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Neutrophil degranulation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cd68 ENSMUSG00000018774 0.000844544805216501 0.0025336344156495 0.0331400397096515 0.0497100595644772 0.0566379395854602 0.0566379395854602
Hk3 ENSMUSG00000025877 4.34560606330504e-05 0.000130368181899151 0.852940894477647 0.852940894477647 0.00446325197783099 0.00669487796674649
Ptprc ENSMUSG00000026395 0.00289311433957183 0.00867934301871548 0.18064054691103 0.270960820366546 0.299349060054895 0.299349060054895
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Siglec5 ENSMUSG00000039013 0.094755898098955 0.0964252305385472 0.0964252305385472 0.0964252305385472 0.0241933715424143 0.0725801146272428
C3ar1 ENSMUSG00000040552 5.46967066778586e-05 5.62387620362729e-05 5.46967066778587e-05 5.62387620362729e-05 5.62387620362729e-05 5.62387620362729e-05
C5ar1 ENSMUSG00000049130 5.17062302895135e-05 7.75593454342704e-05 5.17062302895136e-05 7.75593454342704e-05 0.00153425095635554 0.00153425095635554
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935
Ptafr ENSMUSG00000056529 5.31859920215278e-05 0.000159557976064583 0.78132892626786 0.78132892626786 0.178901132102685 0.268351698154027
Fcer1g ENSMUSG00000058715 5.78125466309114e-05 0.000173437639892734 0.0766111619812296 0.0766111619812296 0.058823267388015 0.0766111619812296
Pirb ENSMUSG00000058818 0.00477055016690543 0.0143116505007163 0.119631084167592 0.179446626251387 0.295581119060361 0.295581119060361
Fcgr4 ENSMUSG00000059089 0.00159435459956481 0.00239153189934721 0.0231500557096833 0.0231500557096833 0.000154022412522137 0.00046206723756641
Gm14851 ENSMUSG00000061958 0.113190884633071 0.339572653899212 0.926333123228344 0.926333123228344 0.450794830295119 0.676192245442679
Ear2 ENSMUSG00000072596 0.290984282074805 0.340887582990546 0.0129100470219435 0.0387301410658306 0.340887582990546 0.340887582990546
Ifi204 ENSMUSG00000073489 2.05510033519727e-05 6.1653010055918e-05 0.00113663395596434 0.0017049509339465 0.120545895661627 0.120545895661627
Gm14548 ENSMUSG00000074417 0.00437574110570137 0.00437574110570139 0.00437574110570136 0.00437574110570139 0.00437574110570139 0.00437574110570139

TRIF-mediated programmed cell death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Regulation of TLR by endogenous ligand

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074

Toll-like Receptor Cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Ctss ENSMUSG00000038642 5.17062302895137e-05 0.000155118690868541 0.00649065913668484 0.00973598870502726 0.148772260628989 0.148772260628989
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tlr7 ENSMUSG00000044583 5.46967066778586e-05 0.000164090120033576 0.643853282854191 0.643853282854191 0.398108175780842 0.597162263671263
Tlr1 ENSMUSG00000044827 0.000140686063028723 0.00042205818908617 0.781645261743309 0.781645261743309 0.575246939700399 0.781645261743309
Tlr6 ENSMUSG00000051498 0.00159435459956481 0.00478306379869443 0.781170242226513 0.781170242226513 0.17924968721805 0.268874530827074
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Programmed Cell Death

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024
Bmf ENSMUSG00000040093 0.000807274199958707 0.00242182259987612 0.853694531487825 0.853694531487825 0.509471754007076 0.764207631010614
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

TRAIL signaling

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tnfrsf10b ENSMUSG00000022074 0.0203667645486189 0.0611002936458567 0.707899741868332 0.85326530496423 0.85326530496423 0.85326530496423
Tnfsf10 ENSMUSG00000039304 0.000150607396432639 0.000451822189297917 0.295581119060361 0.295581119060361 0.17750354896016 0.26625532344024

IKK complex recruitment mediated by RIP1

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ripk3 ENSMUSG00000022221 0.0105895396009763 0.0317686188029288 0.853694531487825 0.853694531487825 0.642117186565222 0.853694531487825
Tlr4 ENSMUSG00000039005 4.88380184963456e-05 7.97789880322924e-05 5.31859920215282e-05 7.97789880322924e-05 0.00761949030813566 0.00761949030813566
Ticam2 ENSMUSG00000056130 5.46967066778587e-05 0.000164090120033576 0.00267929328757356 0.00267929328757356 0.00161470887631957 0.00242206331447935

Chemokine receptors bind chemokines

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ccl4 ENSMUSG00000018930 0.000795094181770697 0.00218450827004161 0.254787123615605 0.254787123615605 0.00145633884669441 0.00218450827004161
Cxcl10 ENSMUSG00000034855 0.00463747559282089 0.0139124267784627 0.0232795908282424 0.0349193862423635 0.0441715176243983 0.0441715176243983
Ccl12 ENSMUSG00000035352 0.00755778364492931 0.0166000435290506 0.0743693776059063 0.0743693776059063 0.0110666956860337 0.0166000435290506
Ccr5 ENSMUSG00000079227 0.00264953297731415 0.00424655905783326 0.00283103937188884 0.00424655905783326 0.00481536616919077 0.00481536616919077

plum

[1] “No significantly overrepresented pathways reported”

rosybrown2

Heme degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slco2b1 ENSMUSG00000030737 0.0240620856673909 0.0721862570021728 0.286303237509397 0.286303237509397 0.0583853430099097 0.0875780145148645
Ugt1a1 ENSMUSG00000089960 0.00981618413649362 0.00981618413649362 0.00981618413649362 0.00981618413649362 1.36782244731604e-06 4.10346734194812e-06

Metabolism of porphyrins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slco2b1 ENSMUSG00000030737 0.0240620856673909 0.0721862570021728 0.286303237509397 0.286303237509397 0.0583853430099097 0.0875780145148645
Ugt1a1 ENSMUSG00000089960 0.00981618413649362 0.00981618413649362 0.00981618413649362 0.00981618413649362 1.36782244731604e-06 4.10346734194812e-06

salmon

Metabolic pathways

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Inmt ENSMUSG00000003477 0.000164597779190222 0.000493793337570667 0.297848640636702 0.446772960955053 0.454942951775341 0.454942951775341
Gcdh ENSMUSG00000003809 0.710001140920767 0.710001140920767 0.344663224299303 0.683948417459205 0.45596561163947 0.683948417459205
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Cox4i2 ENSMUSG00000009876 0.0226344734406829 0.0679034203220486 0.346527959006435 0.346527959006435 0.178901132102685 0.268351698154027
Tha1 ENSMUSG00000017713 0.148772260628989 0.446316781886968 0.642864324224729 0.642864324224729 0.577829325134931 0.642864324224729
Pah ENSMUSG00000020051 0.33666168456718 0.448685536739372 0.448685536739372 0.448685536739372 0.140833168780851 0.422499506342554
Entpd5 ENSMUSG00000021236 0.214037080764325 0.321055621146488 0.501096336601183 0.501096336601183 0.142165951159432 0.321055621146488
Miox ENSMUSG00000022613 0.100142809440036 0.128671938873094 0.128671938873094 0.128671938873094 0.128671938873094 0.128671938873094
Hgd ENSMUSG00000022821 0.338207314205573 0.449743164679353 0.449743164679353 0.449743164679353 0.241452668344063 0.449743164679353
Keg1 ENSMUSG00000024694 0.266691704299975 0.484508824042708 0.484508824042708 0.484508824042708 0.360205830796318 0.484508824042708
Hoga1 ENSMUSG00000025176 0.710208797518812 0.7802108304765 0.7802108304765 0.7802108304765 0.209636747299872 0.628910241899617
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Acmsd ENSMUSG00000026348 0.563170866775883 0.844756300163824 0.55137861489632 0.844756300163824 0.921273194899708 0.921273194899708
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Cyp2j13 ENSMUSG00000028571 0.762100360299702 0.762100360299702 0.762100360299702 0.762100360299702 0.283035017896867 0.762100360299702
Acsm2 ENSMUSG00000030945 0.208156293081417 0.312234439622125 0.138826917499775 0.312234439622125 0.342405296020881 0.342405296020881
Aldh8a1 ENSMUSG00000037542 0.925387810388836 0.925387810388836 0.847921313356738 0.925387810388836 0.0905746262847312 0.271723878854194
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Kmo ENSMUSG00000039783 0.398829756175299 0.578113371816017 0.578113371816017 0.578113371816017 0.513665062682276 0.578113371816017
Pklr ENSMUSG00000041237 0.00309588067649958 0.00928764202949875 0.533305492606139 0.533305492606139 0.473977134394392 0.533305492606139
Dao ENSMUSG00000042096 0.0349943506198951 0.104983051859685 0.780851835278818 0.781170242226513 0.781170242226513 0.781170242226513
Cyp2j5 ENSMUSG00000052520 0.188668414543647 0.28300262181547 0.0954397432376676 0.28300262181547 0.443306001726868 0.443306001726868
Gsta2 ENSMUSG00000057933 0.223767744186666 0.335651616279998 0.565358226870967 0.565358226870967 0.115184763044727 0.335651616279998
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
Acnat1 ENSMUSG00000070985 1 1 1 1 0.615734841980377 1
Gm10639 ENSMUSG00000074179 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843
Agxt2 ENSMUSG00000089678 0.826290760660065 1 1 1 0.826290760660065 1

Fatty acid degradation

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gcdh ENSMUSG00000003809 0.710001140920767 0.710001140920767 0.344663224299303 0.683948417459205 0.45596561163947 0.683948417459205
Eci3 ENSMUSG00000021416 0.638051880670243 0.638051880670243 0.114729876360359 0.344189629081078 0.248007862766528 0.372011794149792
Cpt2 ENSMUSG00000028607 0.513665062682276 0.643359829732651 0.643359829732651 0.643359829732651 0.300095920620218 0.643359829732651
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Drug metabolism - other enzymes

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Ces1f ENSMUSG00000031725 0.633039971999413 0.845463210524231 0.845463210524231 0.845463210524231 0.433220407661116 0.845463210524231
Gsta2 ENSMUSG00000057933 0.223767744186666 0.335651616279998 0.565358226870967 0.565358226870967 0.115184763044727 0.335651616279998
Ces2c ENSMUSG00000061825 0.70108331127338 0.70108331127338 0.175749000247038 0.357473031653191 0.238315354435461 0.357473031653191
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Ces1e ENSMUSG00000061959 0.650262661949838 0.650262661949838 0.650262661949838 0.650262661949838 0.280002632651122 0.650262661949838
Gm10639 ENSMUSG00000074179 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552

Glycolysis / Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Pklr ENSMUSG00000041237 0.00309588067649958 0.00928764202949875 0.533305492606139 0.533305492606139 0.473977134394392 0.533305492606139
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843

Tryptophan metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Inmt ENSMUSG00000003477 0.000164597779190222 0.000493793337570667 0.297848640636702 0.446772960955053 0.454942951775341 0.454942951775341
Gcdh ENSMUSG00000003809 0.710001140920767 0.710001140920767 0.344663224299303 0.683948417459205 0.45596561163947 0.683948417459205
Acmsd ENSMUSG00000026348 0.563170866775883 0.844756300163824 0.55137861489632 0.844756300163824 0.921273194899708 0.921273194899708
Aldh8a1 ENSMUSG00000037542 0.925387810388836 0.925387810388836 0.847921313356738 0.925387810388836 0.0905746262847312 0.271723878854194
Kmo ENSMUSG00000039783 0.398829756175299 0.578113371816017 0.578113371816017 0.578113371816017 0.513665062682276 0.578113371816017

Arachidonic acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Cyp2j13 ENSMUSG00000028571 0.762100360299702 0.762100360299702 0.762100360299702 0.762100360299702 0.283035017896867 0.762100360299702
Cyp2j5 ENSMUSG00000052520 0.188668414543647 0.28300262181547 0.0954397432376676 0.28300262181547 0.443306001726868 0.443306001726868
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Bile secretion

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Slc51a ENSMUSG00000035699 1 1 0.69970808415212 1 1 1
Slco1a1 ENSMUSG00000041698 0.202543053799149 0.303814580698723 0.444394285043028 0.444394285043028 0.198746427756693 0.303814580698723
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Slc22a7 ENSMUSG00000067144 0.392985378348026 0.392985378348026 0.0439832496172286 0.131949748851686 0.212577112625022 0.318865668937533
Acnat1 ENSMUSG00000070985 1 1 1 1 0.615734841980377 1

Drug metabolism - cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Gsta2 ENSMUSG00000057933 0.223767744186666 0.335651616279998 0.565358226870967 0.565358226870967 0.115184763044727 0.335651616279998
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Gm10639 ENSMUSG00000074179 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Metabolism of xenobiotics by cytochrome P450

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Gsta2 ENSMUSG00000057933 0.223767744186666 0.335651616279998 0.565358226870967 0.565358226870967 0.115184763044727 0.335651616279998
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Gm10639 ENSMUSG00000074179 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Peroxisome

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Eci3 ENSMUSG00000021416 0.638051880670243 0.638051880670243 0.114729876360359 0.344189629081078 0.248007862766528 0.372011794149792
Pecr ENSMUSG00000026189 0.778911768167544 0.778911768167544 0.00561257135151671 0.0168377140545501 0.633039971999413 0.778911768167544
Abcd1 ENSMUSG00000031378 0.0566379395854603 0.137954260826001 0.643359829732651 0.643359829732651 0.091969507217334 0.137954260826001
Dao ENSMUSG00000042096 0.0349943506198951 0.104983051859685 0.780851835278818 0.781170242226513 0.781170242226513 0.781170242226513
Acnat1 ENSMUSG00000070985 1 1 1 1 0.615734841980377 1

PPAR signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Fabp6 ENSMUSG00000020405 0.926604389137101 0.926604389137101 0.780692109850228 0.926604389137101 0.925948247631505 0.926604389137101
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Cpt2 ENSMUSG00000028607 0.513665062682276 0.643359829732651 0.643359829732651 0.643359829732651 0.300095920620218 0.643359829732651
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Complement and coagulation cascades

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Proc ENSMUSG00000024386 1 1 0.361067143249407 1 0.777255087907932 1
F5 ENSMUSG00000026579 0.347269605097055 0.347269605097055 0.346156228791382 0.347269605097055 0.347269605097055 0.347269605097055
Serpinf2 ENSMUSG00000038224 0.110625408309089 0.110625408309089 0.0207385937591113 0.0622157812773338 0.0477461412148283 0.0716192118222424
Vsig4 ENSMUSG00000044206 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552
Kng2 ENSMUSG00000060459 0.347269605097055 0.399548817627028 0.144157978128026 0.399548817627028 0.399548817627028 0.399548817627028

Chemical carcinogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Gsta2 ENSMUSG00000057933 0.223767744186666 0.335651616279998 0.565358226870967 0.565358226870967 0.115184763044727 0.335651616279998
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Gm10639 ENSMUSG00000074179 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552 0.275387266314552
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Inflammatory mediator regulation of TRP channels

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2j13 ENSMUSG00000028571 0.762100360299702 0.762100360299702 0.762100360299702 0.762100360299702 0.283035017896867 0.762100360299702
Cyp2j5 ENSMUSG00000052520 0.188668414543647 0.28300262181547 0.0954397432376676 0.28300262181547 0.443306001726868 0.443306001726868
Kng2 ENSMUSG00000060459 0.347269605097055 0.399548817627028 0.144157978128026 0.399548817627028 0.399548817627028 0.399548817627028
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Glycine, serine and threonine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tha1 ENSMUSG00000017713 0.148772260628989 0.446316781886968 0.642864324224729 0.642864324224729 0.577829325134931 0.642864324224729
Dao ENSMUSG00000042096 0.0349943506198951 0.104983051859685 0.780851835278818 0.781170242226513 0.781170242226513 0.781170242226513
Agxt2 ENSMUSG00000089678 0.826290760660065 1 1 1 0.826290760660065 1

Biosynthesis of amino acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Tha1 ENSMUSG00000017713 0.148772260628989 0.446316781886968 0.642864324224729 0.642864324224729 0.577829325134931 0.642864324224729
Pah ENSMUSG00000020051 0.33666168456718 0.448685536739372 0.448685536739372 0.448685536739372 0.140833168780851 0.422499506342554
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Pklr ENSMUSG00000041237 0.00309588067649958 0.00928764202949875 0.533305492606139 0.533305492606139 0.473977134394392 0.533305492606139

AMPK signaling pathway

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Hnf4a ENSMUSG00000017950 0.27952326084055 0.27952326084055 0.0522707201909891 0.128319402462014 0.0855462683080096 0.128319402462014
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Rheb ENSMUSG00000028945 0.57113445032749 0.643359829732651 0.643359829732651 0.643359829732651 0.337435786255283 0.643359829732651
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843

Taurine and hypotaurine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Acnat1 ENSMUSG00000070985 1 1 1 1 0.615734841980377 1

Metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Gcdh ENSMUSG00000003809 0.710001140920767 0.710001140920767 0.344663224299303 0.683948417459205 0.45596561163947 0.683948417459205
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Pah ENSMUSG00000020051 0.33666168456718 0.448685536739372 0.448685536739372 0.448685536739372 0.140833168780851 0.422499506342554
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Fabp6 ENSMUSG00000020405 0.926604389137101 0.926604389137101 0.780692109850228 0.926604389137101 0.925948247631505 0.926604389137101
Akr1c21 ENSMUSG00000021207 0.780049698709835 0.780049698709835 0.283532857713707 0.42529928657056 0.162867964743396 0.42529928657056
Entpd5 ENSMUSG00000021236 0.214037080764325 0.321055621146488 0.501096336601183 0.501096336601183 0.142165951159432 0.321055621146488
Gpihbp1 ENSMUSG00000022579 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759063 0.0714818202759065
Miox ENSMUSG00000022613 0.100142809440036 0.128671938873094 0.128671938873094 0.128671938873094 0.128671938873094 0.128671938873094
Hgd ENSMUSG00000022821 0.338207314205573 0.449743164679353 0.449743164679353 0.449743164679353 0.241452668344063 0.449743164679353
Sult1c2 ENSMUSG00000023122 0.272977814061365 0.272977814061365 0.272977814061365 0.272977814061365 0.0680278868695481 0.204083660608644
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Slc23a1 ENSMUSG00000024354 0.691540081432959 0.691540081432959 0.555414221630051 0.691540081432959 0.165511506369963 0.49653451910989
Acy3 ENSMUSG00000024866 0.450444934184774 0.575536202757516 0.575536202757516 0.575536202757516 0.33116978622016 0.575536202757516
Hoga1 ENSMUSG00000025176 0.710208797518812 0.7802108304765 0.7802108304765 0.7802108304765 0.209636747299872 0.628910241899617
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Pecr ENSMUSG00000026189 0.778911768167544 0.778911768167544 0.00561257135151671 0.0168377140545501 0.633039971999413 0.778911768167544
Lrp2 ENSMUSG00000027070 0.162139598711651 0.162139598711651 0.0807923312542955 0.121188496881443 0.000795094181770697 0.00238528254531209
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Cpt2 ENSMUSG00000028607 0.513665062682276 0.643359829732651 0.643359829732651 0.643359829732651 0.300095920620218 0.643359829732651
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Hsd17b14 ENSMUSG00000030825 0.623236974567196 0.623236974567196 0.0754817925472773 0.226445377641832 0.177476619618252 0.266214929427378
Acsm2 ENSMUSG00000030945 0.208156293081417 0.312234439622125 0.138826917499775 0.312234439622125 0.342405296020881 0.342405296020881
Abcd1 ENSMUSG00000031378 0.0566379395854603 0.137954260826001 0.643359829732651 0.643359829732651 0.091969507217334 0.137954260826001
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Kmo ENSMUSG00000039783 0.398829756175299 0.578113371816017 0.578113371816017 0.578113371816017 0.513665062682276 0.578113371816017
Ugt3a2 ENSMUSG00000049152 0.308275243702282 0.308275243702282 0.111328716096743 0.260706069733079 0.173804046488719 0.260706069733079
Ttr ENSMUSG00000061808 0.577259514257969 0.641867098978197 0.641867098978197 0.641867098978197 0.453570536021945 0.641867098978197
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843
Agxt2 ENSMUSG00000089678 0.826290760660065 1 1 1 0.826290760660065 1

Biological oxidations

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Sult1c2 ENSMUSG00000023122 0.272977814061365 0.272977814061365 0.272977814061365 0.272977814061365 0.0680278868695481 0.204083660608644
Acy3 ENSMUSG00000024866 0.450444934184774 0.575536202757516 0.575536202757516 0.575536202757516 0.33116978622016 0.575536202757516
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Acsm2 ENSMUSG00000030945 0.208156293081417 0.312234439622125 0.138826917499775 0.312234439622125 0.342405296020881 0.342405296020881
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Ugt3a2 ENSMUSG00000049152 0.308275243702282 0.308275243702282 0.111328716096743 0.260706069733079 0.173804046488719 0.260706069733079
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

SLC-mediated transmembrane transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Slc13a5 ENSMUSG00000020805 0.853694531487825 0.853694531487825 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Slc17a1 ENSMUSG00000021335 0.160678859790995 0.197981832648792 0.197981832648792 0.197981832648792 0.0979503281169397 0.197981832648792
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Slc3a1 ENSMUSG00000024131 0.513665062682276 0.513665062682276 0.252545530864481 0.513665062682276 0.344663224299303 0.513665062682276
Slc13a1 ENSMUSG00000029700 0.642117186565222 0.642117186565222 0.573498913947369 0.642117186565222 0.450094379653806 0.642117186565222
Slc5a2 ENSMUSG00000030781 0.093553775622539 0.280330119094232 0.280330119094232 0.280330119094232 0.280330119094232 0.280330119094232
Slc12a3 ENSMUSG00000031766 0.11595859961889 0.262038348050444 0.291756209988535 0.291756209988535 0.174692232033629 0.262038348050444
Slc5a12 ENSMUSG00000041644 0.626117476225324 0.939176214337986 0.626117476225324 0.939176214337986 1 1

Synthesis of Leukotrienes (LT) and Eoxins (EX)

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Transport of inorganic cations/anions and amino acids/oligopeptides

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Slc17a1 ENSMUSG00000021335 0.160678859790995 0.197981832648792 0.197981832648792 0.197981832648792 0.0979503281169397 0.197981832648792
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Slc3a1 ENSMUSG00000024131 0.513665062682276 0.513665062682276 0.252545530864481 0.513665062682276 0.344663224299303 0.513665062682276
Slc12a3 ENSMUSG00000031766 0.11595859961889 0.262038348050444 0.291756209988535 0.291756209988535 0.174692232033629 0.262038348050444
Slc5a12 ENSMUSG00000041644 0.626117476225324 0.939176214337986 0.626117476225324 0.939176214337986 1 1

Fatty acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Pecr ENSMUSG00000026189 0.778911768167544 0.778911768167544 0.00561257135151671 0.0168377140545501 0.633039971999413 0.778911768167544
Cpt2 ENSMUSG00000028607 0.513665062682276 0.643359829732651 0.643359829732651 0.643359829732651 0.300095920620218 0.643359829732651
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Abcd1 ENSMUSG00000031378 0.0566379395854603 0.137954260826001 0.643359829732651 0.643359829732651 0.091969507217334 0.137954260826001
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Gluconeogenesis

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843

Arachidonic acid metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Transport of bile salts and organic acids, metal ions and amine compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc13a5 ENSMUSG00000020805 0.853694531487825 0.853694531487825 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Slc13a1 ENSMUSG00000029700 0.642117186565222 0.642117186565222 0.573498913947369 0.642117186565222 0.450094379653806 0.642117186565222

Phase I - Functionalization of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Na+/Cl- dependent neurotransmitter transporters

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712

Cytochrome P450 - arranged by substrate type

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Transport of small molecules

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Slc13a5 ENSMUSG00000020805 0.853694531487825 0.853694531487825 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Slc17a1 ENSMUSG00000021335 0.160678859790995 0.197981832648792 0.197981832648792 0.197981832648792 0.0979503281169397 0.197981832648792
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Gpihbp1 ENSMUSG00000022579 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759063 0.0714818202759065
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Slc3a1 ENSMUSG00000024131 0.513665062682276 0.513665062682276 0.252545530864481 0.513665062682276 0.344663224299303 0.513665062682276
Slc13a1 ENSMUSG00000029700 0.642117186565222 0.642117186565222 0.573498913947369 0.642117186565222 0.450094379653806 0.642117186565222
Slc5a2 ENSMUSG00000030781 0.093553775622539 0.280330119094232 0.280330119094232 0.280330119094232 0.280330119094232 0.280330119094232
Abcd1 ENSMUSG00000031378 0.0566379395854603 0.137954260826001 0.643359829732651 0.643359829732651 0.091969507217334 0.137954260826001
Slc12a3 ENSMUSG00000031766 0.11595859961889 0.262038348050444 0.291756209988535 0.291756209988535 0.174692232033629 0.262038348050444
Slc17a3 ENSMUSG00000036083 0.215371954237013 0.323057931355519 0.920735042422376 0.920735042422376 0.206306404952926 0.323057931355519
Azgp1 ENSMUSG00000037053 0.511420431658568 0.708534948098331 0.0286197688015878 0.0858593064047634 0.708534948098331 0.708534948098331
Slc5a12 ENSMUSG00000041644 0.626117476225324 0.939176214337986 0.626117476225324 0.939176214337986 1 1

Retinoid metabolism and transport

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr1c21 ENSMUSG00000021207 0.780049698709835 0.780049698709835 0.283532857713707 0.42529928657056 0.162867964743396 0.42529928657056
Gpihbp1 ENSMUSG00000022579 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759063 0.0714818202759065
Lrp2 ENSMUSG00000027070 0.162139598711651 0.162139598711651 0.0807923312542955 0.121188496881443 0.000795094181770697 0.00238528254531209
Ttr ENSMUSG00000061808 0.577259514257969 0.641867098978197 0.641867098978197 0.641867098978197 0.453570536021945 0.641867098978197

Eicosanoids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Sodium-coupled sulphate, di- and tri-carboxylate transporters

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc13a5 ENSMUSG00000020805 0.853694531487825 0.853694531487825 0.255530331334266 0.683948417459205 0.45596561163947 0.683948417459205
Slc13a1 ENSMUSG00000029700 0.642117186565222 0.642117186565222 0.573498913947369 0.642117186565222 0.450094379653806 0.642117186565222

Metabolism of fat-soluble vitamins

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Akr1c21 ENSMUSG00000021207 0.780049698709835 0.780049698709835 0.283532857713707 0.42529928657056 0.162867964743396 0.42529928657056
Gpihbp1 ENSMUSG00000022579 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759063 0.0714818202759065
Lrp2 ENSMUSG00000027070 0.162139598711651 0.162139598711651 0.0807923312542955 0.121188496881443 0.000795094181770697 0.00238528254531209
Ttr ENSMUSG00000061808 0.577259514257969 0.641867098978197 0.641867098978197 0.641867098978197 0.453570536021945 0.641867098978197

Aflatoxin activation and detoxification

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Acy3 ENSMUSG00000024866 0.450444934184774 0.575536202757516 0.575536202757516 0.575536202757516 0.33116978622016 0.575536202757516

Abacavir transport and metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc22a1 ENSMUSG00000023829 0.455284468727762 0.455284468727762 0.179597906187076 0.316665516599712 0.211110344399808 0.316665516599712
Adh1 ENSMUSG00000074207 0.0113089139751575 0.0339267419254726 0.215852522998047 0.215852522998047 0.17750354896016 0.215852522998047

Fatty acids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Phase II - Conjugation of compounds

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Sult1c2 ENSMUSG00000023122 0.272977814061365 0.272977814061365 0.272977814061365 0.272977814061365 0.0680278868695481 0.204083660608644
Acsm2 ENSMUSG00000030945 0.208156293081417 0.312234439622125 0.138826917499775 0.312234439622125 0.342405296020881 0.342405296020881
Ugt3a2 ENSMUSG00000049152 0.308275243702282 0.308275243702282 0.111328716096743 0.260706069733079 0.173804046488719 0.260706069733079
Ugt2b38 ENSMUSG00000061906 0.332357524271191 0.332357524271191 0.233545092161713 0.332357524271191 0.155153716405811 0.332357524271191

Metabolism of lipids

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Ggt1 ENSMUSG00000006345 0.0165780605008444 0.0497341815025331 0.254041925545275 0.381062888317912 0.51398322803049 0.51398322803049
Dpep1 ENSMUSG00000019278 0.287873078401389 0.291756209988535 0.108244222162358 0.291756209988535 0.291756209988535 0.291756209988535
Fabp6 ENSMUSG00000020405 0.926604389137101 0.926604389137101 0.780692109850228 0.926604389137101 0.925948247631505 0.926604389137101
Akr1c21 ENSMUSG00000021207 0.780049698709835 0.780049698709835 0.283532857713707 0.42529928657056 0.162867964743396 0.42529928657056
Cyp2e1 ENSMUSG00000025479 0.0813516514405566 0.167569692867573 0.163231646296655 0.167569692867573 0.167569692867573 0.167569692867573
Pecr ENSMUSG00000026189 0.778911768167544 0.778911768167544 0.00561257135151671 0.0168377140545501 0.633039971999413 0.778911768167544
Cpt2 ENSMUSG00000028607 0.513665062682276 0.643359829732651 0.643359829732651 0.643359829732651 0.300095920620218 0.643359829732651
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Hsd17b14 ENSMUSG00000030825 0.623236974567196 0.623236974567196 0.0754817925472773 0.226445377641832 0.177476619618252 0.266214929427378
Abcd1 ENSMUSG00000031378 0.0566379395854603 0.137954260826001 0.643359829732651 0.643359829732651 0.091969507217334 0.137954260826001
Cyp24a1 ENSMUSG00000038567 0.454600801949285 0.681901202923927 0.782117202022501 0.782117202022501 0.397384062266614 0.681901202923927
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Miscellaneous substrates

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Cyp4b1 ENSMUSG00000028713 0.0676641944946708 0.202992583484012 0.449391287230099 0.449391287230099 0.392985378348026 0.449391287230099
Cyp4a12a ENSMUSG00000066071 0.574957087247654 0.777422433431083 0.340887582990546 0.777422433431083 0.777422433431083 0.777422433431083
Cyp4a10 ENSMUSG00000066072 0.513346277289108 0.513346277289108 0.0432318933800775 0.0648478400701163 0.00689577866107723 0.0206873359832317

Organic anion transporters

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Slc17a1 ENSMUSG00000021335 0.160678859790995 0.197981832648792 0.197981832648792 0.197981832648792 0.0979503281169397 0.197981832648792

Amino acid transport across the plasma membrane

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc6a19 ENSMUSG00000021565 0.113498953177704 0.113498953177704 0.10607024422363 0.113498953177704 0.0211129141819613 0.063338742545884
Slc6a18 ENSMUSG00000021612 0.339455591684983 0.339455591684983 0.339455591684982 0.339455591684983 0.334005406732082 0.339455591684983
Slc3a1 ENSMUSG00000024131 0.513665062682276 0.513665062682276 0.252545530864481 0.513665062682276 0.344663224299303 0.513665062682276

Phenylalanine and tyrosine metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pah ENSMUSG00000020051 0.33666168456718 0.448685536739372 0.448685536739372 0.448685536739372 0.140833168780851 0.422499506342554
Hgd ENSMUSG00000022821 0.338207314205573 0.449743164679353 0.449743164679353 0.449743164679353 0.241452668344063 0.449743164679353

Metabolism of vitamins and cofactors

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Slc5a8 ENSMUSG00000020062 0.0716332429957515 0.107449864493627 0.0111471670220256 0.0334415010660767 0.201787232060998 0.201787232060998
Akr1c21 ENSMUSG00000021207 0.780049698709835 0.780049698709835 0.283532857713707 0.42529928657056 0.162867964743396 0.42529928657056
Gpihbp1 ENSMUSG00000022579 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759065 0.0714818202759063 0.0714818202759065
Slc23a1 ENSMUSG00000024354 0.691540081432959 0.691540081432959 0.555414221630051 0.691540081432959 0.165511506369963 0.49653451910989
Lrp2 ENSMUSG00000027070 0.162139598711651 0.162139598711651 0.0807923312542955 0.121188496881443 0.000795094181770697 0.00238528254531209
Ttr ENSMUSG00000061808 0.577259514257969 0.641867098978197 0.641867098978197 0.641867098978197 0.453570536021945 0.641867098978197

Glucose metabolism

External Gene Name Gene ID Treatment BH Treatment Time BH Time Treatment by time BH Treatment by time
Pck1 ENSMUSG00000027513 0.0596790692127121 0.179037207638136 0.224181550151583 0.224181550151583 0.135822459651308 0.203733689476963
Aldob ENSMUSG00000028307 0.442211413534162 0.443669460449296 0.443669460449296 0.443669460449296 0.171503747555202 0.443669460449296
Fbp1 ENSMUSG00000069805 0.230726300740048 0.415631546667314 0.27708769777821 0.415631546667314 0.443306001726868 0.443306001726868
G6pc ENSMUSG00000078650 0.369144336710984 0.369144336710984 0.109921446533464 0.209345880207843 0.139563920138562 0.209345880207843

Analysis performed by Ann Wells

The Carter Lab The Jackson Laboratory 2023

ann.wells@jax.org